US20220000056A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2578 0.7666 0.0 0
M  V30 3 C -1.3297 0.7666 0.0 0
M  V30 4 C 1.2219 2.3 0.0 0
M  V30 5 C 2.5157 0.0359 0.0 0
M  V30 6 C -1.3656 2.3 0.0 0 CFG=2
M  V30 7 C -2.1084 -0.4911 0.0 0
M  V30 8 C -2.8631 0.8026 0.0 0
M  V30 9 C 2.4797 3.0667 0.0 0
M  V30 10 C -0.1078 3.0667 0.0 0
M  V30 11 C 3.7735 0.8146 0.0 0
M  V30 12 C -2.6954 3.0667 0.0 0
M  V30 13 O 2.4438 4.6001 0.0 0
M  V30 14 C 3.7376 2.348 0.0 0
M  V30 15 C -0.1437 4.6001 0.0 0
M  V30 16 C 5.0314 0.0838 0.0 0
M  V30 17 C -2.7313 4.6001 0.0 0
M  V30 18 C -1.4734 5.3788 0.0 0
M  V30 19 C 6.2892 0.8625 0.0 0
M  V30 20 C -1.5094 6.9122 0.0 0
M  V30 21 C 7.5471 0.1317 0.0 0
M  V30 22 C 8.805 0.9104 0.0 0
M  V30 23 C 10.0628 0.1796 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 3 8
M  V30 8 1 4 9
M  V30 9 1 4 10
M  V30 10 2 5 11
M  V30 11 1 6 12 CFG=1
M  V30 12 1 9 13
M  V30 13 2 9 14
M  V30 14 1 10 15
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 2 15 18
M  V30 18 1 16 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 6 10
M  V30 24 1 11 14
M  V30 25 1 17 18
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 6)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000056A1-20220106-C00001

>  <Row No>
1

$$$$
US20220000056A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0358 -1.4578 0.0 0
M  V30 3 O 1.2188 -2.1748 0.0 0
M  V30 4 C -1.3622 -2.1748 0.0 0
M  V30 5 C -2.6886 -1.398 0.0 0
M  V30 6 C -1.398 -3.6326 0.0 0
M  V30 7 O -2.7244 0.1314 0.0 0
M  V30 8 C -4.015 -2.115 0.0 0
M  V30 9 C -2.7244 -4.3615 0.0 0
M  V30 10 C -0.1433 -4.3615 0.0 0
M  V30 11 C -4.0508 -3.5728 0.0 0
M  V30 12 C -5.3414 -1.3383 0.0 0 CFG=2
M  V30 13 C 1.1112 -3.5967 0.0 0
M  V30 14 O -5.3772 -4.3018 0.0 0
M  V30 15 C -5.3772 0.1911 0.0 0
M  V30 16 C -6.6677 -2.0553 0.0 0 CFG=2
M  V30 17 C 2.3659 -4.3257 0.0 0
M  V30 18 C -6.7036 -3.537 0.0 0
M  V30 19 C -6.7036 0.9679 0.0 0
M  V30 20 C -7.9941 -1.2785 0.0 0
M  V30 21 C 3.6206 -3.5609 0.0 0
M  V30 22 C -7.4803 -4.7917 0.0 0
M  V30 23 C -8.2331 -3.5011 0.0 0
M  V30 24 C -8.03 0.2509 0.0 0
M  V30 25 C -6.7394 2.4974 0.0 0
M  V30 26 C 4.8753 -4.2898 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15 CFG=1
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 2 15 19
M  V30 19 1 16 20 CFG=3
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 1 18 23
M  V30 23 1 19 24
M  V30 24 1 19 25
M  V30 25 1 21 26
M  V30 26 1 9 11
M  V30 27 1 16 18
M  V30 28 1 20 24
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 12 16)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000056A1-20220106-C00002

>  <Row No>
2

$$$$
US20220000056A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2558 0.7774 0.0 0
M  V30 3 C 1.2199 2.3084 0.0 0
M  V30 4 C 2.5117 0.0478 0.0 0
M  V30 5 C 2.4758 3.0858 0.0 0
M  V30 6 C -0.1076 3.0858 0.0 0
M  V30 7 C 3.7676 0.8252 0.0 0
M  V30 8 O 2.4399 4.6168 0.0 0
M  V30 9 C 3.7317 2.3562 0.0 0
M  V30 10 C -0.1435 4.6168 0.0 0
M  V30 11 C -1.4352 2.3562 0.0 0
M  V30 12 C 5.0234 0.0956 0.0 0
M  V30 13 C -1.4711 5.3942 0.0 0
M  V30 14 C -1.4711 0.897 0.0 0
M  V30 15 C -2.7629 3.1217 0.0 0
M  V30 16 C 6.2793 0.8731 0.0 0
M  V30 17 C -2.7988 4.6646 0.0 0
M  V30 18 C -1.507 6.9252 0.0 0
M  V30 19 C -2.7988 1.6744 0.0 0
M  V30 20 C -2.7988 0.1674 0.0 0
M  V30 21 C 7.5352 0.1435 0.0 0
M  V30 22 C 8.7911 0.9209 0.0 0
M  V30 23 C 10.0469 0.1913 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 5 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 2 10 13
M  V30 13 1 11 14
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 2 14 19
M  V30 19 1 14 20
M  V30 20 1 16 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 7 9
M  V30 24 1 15 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000056A1-20220106-C00003

>  <Row No>
3

$$$$
US20220000056A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0358 -1.4569 0.0 0
M  V30 3 O 1.218 -2.1853 0.0 0
M  V30 4 C -1.3613 -2.1853 0.0 0
M  V30 5 C -2.6869 -1.4091 0.0 0
M  V30 6 C -1.3972 -3.6423 0.0 0
M  V30 7 O -2.7227 0.1194 0.0 0
M  V30 8 C -4.0125 -2.1376 0.0 0
M  V30 9 C -2.7227 -4.3707 0.0 0
M  V30 10 C -0.1433 -4.3707 0.0 0
M  V30 11 C -4.0483 -3.5945 0.0 0
M  V30 12 C -5.338 -1.3613 0.0 0 CFG=2
M  V30 13 C 1.1106 -3.5945 0.0 0
M  V30 14 O -5.3739 -4.323 0.0 0
M  V30 15 C -5.3739 0.1671 0.0 0
M  V30 16 C -6.6636 -2.0898 0.0 0 CFG=2
M  V30 17 C 2.3645 -4.323 0.0 0
M  V30 18 C -6.6994 0.9434 0.0 0
M  V30 19 C -6.6994 -3.5467 0.0 0
M  V30 20 C -7.9892 -1.3255 0.0 0
M  V30 21 C 3.6184 -3.5467 0.0 0
M  V30 22 C -8.025 0.2149 0.0 0
M  V30 23 C -6.7353 2.4719 0.0 0
M  V30 24 C -8.025 -2.7824 0.0 0
M  V30 25 C -8.025 -4.2752 0.0 0
M  V30 26 C 4.8723 -4.2752 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 2 8 11
M  V30 11 1 12 8 CFG=1
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 2 15 18
M  V30 18 1 16 19 CFG=3
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 1 18 23
M  V30 23 2 19 24
M  V30 24 1 19 25
M  V30 25 1 21 26
M  V30 26 1 9 11
M  V30 27 1 20 22
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 12 16)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000056A1-20220106-C00004

>  <Row No>
4

$$$$
US20220000056A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2586 0.7672 0.0 0
M  V30 3 C 1.2227 2.3016 0.0 0
M  V30 4 C 2.5173 0.0479 0.0 0
M  V30 5 C 2.4814 3.0688 0.0 0
M  V30 6 C -0.1078 3.0688 0.0 0
M  V30 7 C 3.776 0.8271 0.0 0
M  V30 8 O 2.4454 4.6032 0.0 0
M  V30 9 C 3.7401 2.3495 0.0 0
M  V30 10 C -1.4385 2.3495 0.0 0
M  V30 11 C 5.0347 0.1078 0.0 0
M  V30 12 C -2.7691 3.1167 0.0 0
M  V30 13 C 6.2934 0.887 0.0 0
M  V30 14 C -4.0997 2.3975 0.0 0
M  V30 15 C -2.805 4.6511 0.0 0
M  V30 16 C 7.5521 0.1678 0.0 0
M  V30 17 C -5.4303 3.1767 0.0 0
M  V30 18 C 8.8108 0.947 0.0 0
M  V30 19 C -6.7609 2.4574 0.0 0
M  V30 20 C 10.0695 0.2277 0.0 0
M  V30 21 C -8.0916 3.2246 0.0 0
M  V30 22 C -9.4222 2.5053 0.0 0
M  V30 23 C -8.1275 4.759 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 10 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 2 19 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 7 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000056A1-20220106-C00005

>  <Row No>
5

$$$$
US20220000056A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0358 -1.4587 0.0 0
M  V30 3 O 1.2196 -2.1762 0.0 0
M  V30 4 C -1.3631 -2.1762 0.0 0
M  V30 5 C -2.6903 -1.3989 0.0 0
M  V30 6 C -1.3989 -3.6349 0.0 0
M  V30 7 O -2.7262 0.1315 0.0 0
M  V30 8 C -4.0176 -2.1164 0.0 0
M  V30 9 C -2.7262 -4.3524 0.0 0
M  V30 10 C -0.1434 -4.3524 0.0 0
M  V30 11 C -4.0534 -3.5751 0.0 0
M  V30 12 C -5.3448 -1.3392 0.0 0
M  V30 13 C 1.112 -3.5751 0.0 0
M  V30 14 O -5.3807 -4.2926 0.0 0
M  V30 15 C -6.672 -2.0566 0.0 0
M  V30 16 C 2.3675 -4.2926 0.0 0
M  V30 17 C -7.9993 -1.2794 0.0 0
M  V30 18 C 3.623 -3.5154 0.0 0
M  V30 19 C -9.3265 -1.9968 0.0 0
M  V30 20 C -8.0352 0.2511 0.0 0
M  V30 21 C 4.8785 -4.2328 0.0 0
M  V30 22 C -10.6538 -1.2196 0.0 0
M  V30 23 C -11.981 -1.937 0.0 0
M  V30 24 C -13.3083 -1.1718 0.0 0
M  V30 25 C -14.6355 -1.8892 0.0 0
M  V30 26 C -13.3441 0.3587 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 22 23
M  V30 23 2 23 24
M  V30 24 1 24 25
M  V30 25 1 24 26
M  V30 26 1 9 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000056A1-20220106-C00006

>  <Row No>
6

$$$$
US20220000056A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4655 0.0 0
M  V30 3 C -1.3334 0.7688 0.0 0 CFG=2
M  V30 4 C -1.3694 -2.1983 0.0 0
M  V30 5 C 1.2253 -2.1983 0.0 0
M  V30 6 C -2.6668 0.048 0.0 0
M  V30 7 C -2.1022 2.1022 0.0 0
M  V30 8 C -0.6006 2.1022 0.0 0
M  V30 9 C -1.4054 -3.6638 0.0 0
M  V30 10 C -2.7028 -1.4175 0.0 0
M  V30 11 C 1.1892 -3.6638 0.0 0
M  V30 12 C -3.6398 2.1382 0.0 0
M  V30 13 O -2.7389 -4.3966 0.0 0
M  V30 14 C -0.1441 -4.3966 0.0 0
M  V30 15 C 2.4506 -4.3966 0.0 0
M  V30 16 C -4.4206 3.4716 0.0 0
M  V30 17 C 3.7119 -3.6158 0.0 0
M  V30 18 C -5.9583 3.5077 0.0 0
M  V30 19 C 4.9732 -4.3486 0.0 0
M  V30 20 C -6.7391 4.8411 0.0 0
M  V30 21 C -6.7391 2.2463 0.0 0
M  V30 22 C 6.2346 -3.5677 0.0 0
M  V30 23 C 7.4959 -4.3005 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 3 8 CFG=1
M  V30 8 1 4 9
M  V30 9 1 4 10
M  V30 10 2 5 11
M  V30 11 1 7 12
M  V30 12 1 9 13
M  V30 13 2 9 14
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 22 23
M  V30 23 2 6 10
M  V30 24 1 11 14
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 3)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000056A1-20220106-C00007

>  <Row No>
7

$$$$
US20220000056A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2514 0.7746 0.0 0
M  V30 3 O 2.5028 0.0476 0.0 0
M  V30 4 C 1.2156 2.3002 0.0 0
M  V30 5 C -0.1072 3.0629 0.0 0
M  V30 6 C 2.467 3.0629 0.0 0
M  V30 7 O -1.4301 2.3359 0.0 0
M  V30 8 C -0.143 4.5885 0.0 0
M  V30 9 C 2.4313 4.5885 0.0 0
M  V30 10 C 3.7185 2.3359 0.0 0
M  V30 11 C 1.1084 5.3632 0.0 0
M  V30 12 C -1.4659 5.3632 0.0 0
M  V30 13 C 4.9699 3.1106 0.0 0
M  V30 14 O 1.0726 6.8887 0.0 0
M  V30 15 C -1.5017 6.8887 0.0 0
M  V30 16 C 6.2213 2.3836 0.0 0
M  V30 17 C -0.2502 7.6634 0.0 0 CFG=2
M  V30 18 C 7.4727 3.1583 0.0 0
M  V30 19 C -1.0249 8.9863 0.0 0
M  V30 20 C 0.4648 8.9863 0.0 0
M  V30 21 C 8.7241 2.4313 0.0 0
M  V30 22 C -2.5505 9.0221 0.0 0
M  V30 23 C -3.3132 10.345 0.0 0
M  V30 24 C -4.8388 10.3808 0.0 0
M  V30 25 C -5.6135 11.7037 0.0 0
M  V30 26 C -5.6135 9.1294 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 17 20 CFG=1
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 22 23
M  V30 23 2 23 24
M  V30 24 1 24 25
M  V30 25 1 24 26
M  V30 26 1 9 11
M  V30 27 1 15 17
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 17)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000056A1-20220106-C00008

>  <Row No>
8

$$$$
US20220000056A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0361 -1.47 0.0 0
M  V30 3 C -1.3375 0.7711 0.0 0 CFG=2
M  V30 4 C -1.3736 -2.193 0.0 0
M  V30 5 C 1.229 -2.193 0.0 0
M  V30 6 C -2.675 0.0361 0.0 0 CFG=2
M  V30 7 C -1.6869 2.2773 0.0 0
M  V30 8 C -0.0722 1.5423 0.0 0
M  V30 9 C -1.4098 -3.663 0.0 0
M  V30 10 C -2.7111 -1.4218 0.0 0 CFG=1
M  V30 11 C 1.1929 -3.663 0.0 0
M  V30 12 C -3.8197 1.0724 0.0 0 CFG=1
M  V30 13 C -3.2172 2.4701 0.0 0
M  V30 14 O -2.7473 -4.3981 0.0 0
M  V30 15 C -0.1445 -4.3981 0.0 0
M  V30 16 C -3.8558 -0.3855 0.0 0
M  V30 17 C 2.4581 -4.3981 0.0 0
M  V30 18 C -5.3982 -0.3494 0.0 0
M  V30 19 C -4.6391 -1.6507 0.0 0
M  V30 20 C 3.7233 -3.6269 0.0 0
M  V30 21 C 4.9885 -4.3619 0.0 0
M  V30 22 C 6.2537 -3.5907 0.0 0
M  V30 23 C 7.5189 -4.3258 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 6 3 CFG=3
M  V30 6 1 3 7
M  V30 7 1 3 8 CFG=1
M  V30 8 1 4 9
M  V30 9 1 10 4 CFG=3
M  V30 10 2 5 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 1 9 14
M  V30 14 2 9 15
M  V30 15 1 10 16
M  V30 16 1 11 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 1 17 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 6 10
M  V30 24 1 11 15
M  V30 25 1 12 13 CFG=3
M  V30 26 1 12 16
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(4 3 6 10 12)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000056A1-20220106-C00009

>  <Row No>
9

$$$$
US20220000056A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2563 0.7777 0.0 0
M  V30 3 C -1.3281 0.7777 0.0 0
M  V30 4 C 1.2204 2.3092 0.0 0
M  V30 5 C 2.5126 0.0478 0.0 0
M  V30 6 C -1.364 2.3092 0.0 0
M  V30 7 C -2.6562 0.0478 0.0 0
M  V30 8 C -2.6562 1.5435 0.0 0
M  V30 9 C 2.4767 3.075 0.0 0
M  V30 10 C -0.1076 3.075 0.0 0
M  V30 11 C 3.769 0.8255 0.0 0
M  V30 12 C -2.6921 3.075 0.0 0
M  V30 13 O 2.4408 4.6065 0.0 0
M  V30 14 C 3.7331 2.3451 0.0 0
M  V30 15 C -0.1435 4.6065 0.0 0
M  V30 16 C 5.0253 0.0957 0.0 0
M  V30 17 C -2.728 4.6065 0.0 0
M  V30 18 C -1.4717 5.3843 0.0 0
M  V30 19 C 6.2816 0.8734 0.0 0
M  V30 20 C -1.5076 6.9158 0.0 0
M  V30 21 C 7.538 0.1435 0.0 0
M  V30 22 C 8.7943 0.9213 0.0 0
M  V30 23 C 10.0507 0.1914 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 3 8
M  V30 8 1 4 9
M  V30 9 1 4 10
M  V30 10 2 5 11
M  V30 11 1 6 12
M  V30 12 1 9 13
M  V30 13 2 9 14
M  V30 14 1 10 15
M  V30 15 1 11 16
M  V30 16 2 12 17
M  V30 17 2 15 18
M  V30 18 1 16 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 2 6 10
M  V30 24 1 11 14
M  V30 25 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000056A1-20220106-C00010

>  <Row No>
10

$$$$
US20220000056A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0357 -1.4556 0.0 0
M  V30 3 O 1.217 -2.1835 0.0 0
M  V30 4 C -1.3602 -2.1835 0.0 0
M  V30 5 C -2.6846 -1.4079 0.0 0
M  V30 6 C -1.396 -3.6391 0.0 0
M  V30 7 O -2.7204 0.1193 0.0 0
M  V30 8 C -4.009 -2.1357 0.0 0
M  V30 9 C -2.7204 -4.367 0.0 0
M  V30 10 C -0.1431 -4.367 0.0 0
M  V30 11 C -4.0448 -3.5914 0.0 0
M  V30 12 C -5.3334 -1.3602 0.0 0
M  V30 13 C 1.1096 -3.5914 0.0 0
M  V30 14 O -5.3692 -4.3192 0.0 0
M  V30 15 C -6.6579 -2.088 0.0 0
M  V30 16 C -5.3692 0.167 0.0 0
M  V30 17 C 2.3624 -4.3192 0.0 0
M  V30 18 C -6.6937 -3.5437 0.0 0
M  V30 19 C -7.9823 -1.3124 0.0 0
M  V30 20 C -6.6937 0.9426 0.0 0
M  V30 21 C 3.6153 -3.5437 0.0 0
M  V30 22 C -8.0181 -4.2715 0.0 0
M  V30 23 C -8.0181 -2.7681 0.0 0
M  V30 24 C -8.0181 0.2147 0.0 0
M  V30 25 C -6.7295 2.4698 0.0 0
M  V30 26 C 4.8681 -4.2715 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 1 18 23
M  V30 23 2 19 24
M  V30 24 1 20 25
M  V30 25 1 21 26
M  V30 26 1 9 11
M  V30 27 1 15 18
M  V30 28 1 20 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000056A1-20220106-C00011

>  <Row No>
11

$$$$
US20220000056A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2522 0.7752 0.0 0
M  V30 3 C -1.3238 0.7752 0.0 0
M  V30 4 C 1.2164 2.3017 0.0 0
M  V30 5 C 2.5045 0.0477 0.0 0
M  V30 6 C -1.3596 2.3017 0.0 0 CFG=2
M  V30 7 C -2.6476 0.0477 0.0 0
M  V30 8 C -2.6476 1.5504 0.0 0
M  V30 9 C 2.4687 3.077 0.0 0
M  V30 10 C -0.1073 3.077 0.0 0
M  V30 11 C 3.7568 0.8229 0.0 0
M  V30 12 C -2.6834 3.077 0.0 0
M  V30 13 O 2.4329 4.6035 0.0 0
M  V30 14 C 3.721 2.3495 0.0 0
M  V30 15 C -0.1431 4.6035 0.0 0
M  V30 16 C 5.009 0.0954 0.0 0
M  V30 17 C -2.7192 4.6035 0.0 0
M  V30 18 C -1.4669 5.3788 0.0 0
M  V30 19 C 6.2613 0.8706 0.0 0
M  V30 20 C -1.5027 6.9053 0.0 0
M  V30 21 C 7.5136 0.1431 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 3 8
M  V30 8 1 4 9
M  V30 9 1 4 10
M  V30 10 2 5 11
M  V30 11 1 6 12 CFG=1
M  V30 12 1 9 13
M  V30 13 2 9 14
M  V30 14 1 10 15
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 2 15 18
M  V30 18 1 16 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 6 10
M  V30 22 1 11 14
M  V30 23 1 17 18
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 6)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00035001.cdx

>  <name>
US20220000056A1-20220106-C00012

>  <Row No>
12

$$$$
US20220000056A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0357 -1.453 0.0 0
M  V30 3 O 1.2148 -2.1795 0.0 0
M  V30 4 C -1.3577 -2.1795 0.0 0
M  V30 5 C -2.6797 -1.4053 0.0 0
M  V30 6 C -1.3934 -3.6325 0.0 0
M  V30 7 O -2.7154 0.119 0.0 0
M  V30 8 C -4.0017 -2.1318 0.0 0
M  V30 9 C -2.7154 -4.359 0.0 0
M  V30 10 C -0.1429 -4.359 0.0 0
M  V30 11 C -4.0374 -3.5848 0.0 0
M  V30 12 C -5.3237 -1.3577 0.0 0
M  V30 13 C 1.1076 -3.5848 0.0 0
M  V30 14 O -5.3594 -4.3113 0.0 0
M  V30 15 C -5.3594 0.1667 0.0 0
M  V30 16 C -6.6457 -2.0842 0.0 0 CFG=1
M  V30 17 C 2.3581 -4.3113 0.0 0
M  V30 18 C -6.6814 -3.5372 0.0 0
M  V30 19 C -6.6814 0.9408 0.0 0
M  V30 20 C -7.9677 -1.31 0.0 0
M  V30 21 C -8.0034 -4.2637 0.0 0
M  V30 22 C -8.0034 -2.775 0.0 0
M  V30 23 C -8.0034 0.2143 0.0 0
M  V30 24 C -6.7171 2.4653 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 2 15 19
M  V30 19 1 16 20 CFG=1
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 19 24
M  V30 24 1 9 11
M  V30 25 1 16 18
M  V30 26 1 20 23
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 16)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000056A1-20220106-C00013

>  <Row No>
13

$$$$
US20220000056A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2536 0.776 0.0 0
M  V30 3 C 1.2178 2.3043 0.0 0
M  V30 4 C 2.5072 0.0477 0.0 0
M  V30 5 C 2.4714 3.0803 0.0 0
M  V30 6 C -0.1074 3.0803 0.0 0
M  V30 7 C 3.7609 0.8238 0.0 0
M  V30 8 O 2.4356 4.6086 0.0 0
M  V30 9 C 3.7251 2.352 0.0 0
M  V30 10 C -0.1432 4.6086 0.0 0
M  V30 11 C -1.4327 2.352 0.0 0 CFG=1
M  V30 12 C 5.0145 0.0955 0.0 0
M  V30 13 C -1.4685 5.3847 0.0 0
M  V30 14 C -1.4685 0.8954 0.0 0
M  V30 15 C -2.758 3.1281 0.0 0
M  V30 16 C 6.2682 0.8715 0.0 0
M  V30 17 C -2.7938 4.6564 0.0 0
M  V30 18 C -1.5043 6.9129 0.0 0
M  V30 19 C -2.7938 1.6595 0.0 0
M  V30 20 C -2.7938 0.1671 0.0 0
M  V30 21 C 7.5218 0.1432 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 5 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 2 10 13
M  V30 13 1 11 14 CFG=1
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 2 14 19
M  V30 19 1 14 20
M  V30 20 1 16 21
M  V30 21 1 7 9
M  V30 22 1 15 17
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 11)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000056A1-20220106-C00014

>  <Row No>
14

$$$$
US20220000056A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0357 -1.4537 0.0 0
M  V30 3 O 1.2154 -2.1806 0.0 0
M  V30 4 C -1.3584 -2.1806 0.0 0
M  V30 5 C -2.6811 -1.4061 0.0 0
M  V30 6 C -1.3942 -3.6344 0.0 0
M  V30 7 O -2.7169 0.1191 0.0 0
M  V30 8 C -4.0038 -2.133 0.0 0
M  V30 9 C -2.7169 -4.3613 0.0 0
M  V30 10 C -0.1429 -4.3613 0.0 0
M  V30 11 C -4.0396 -3.5867 0.0 0
M  V30 12 C -5.3265 -1.3584 0.0 0
M  V30 13 C 1.1082 -3.5867 0.0 0
M  V30 14 O -5.3623 -4.3136 0.0 0
M  V30 15 C -5.3623 0.1668 0.0 0
M  V30 16 C -6.6492 -2.0853 0.0 0 CFG=1
M  V30 17 C 2.3594 -4.3136 0.0 0
M  V30 18 C -6.685 0.9413 0.0 0
M  V30 19 C -6.685 -3.5391 0.0 0
M  V30 20 C -7.9719 -1.3227 0.0 0
M  V30 21 C -8.0077 0.2144 0.0 0
M  V30 22 C -6.7207 2.4666 0.0 0
M  V30 23 C -8.0077 -2.7645 0.0 0
M  V30 24 C -8.0077 -4.266 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 2 15 18
M  V30 18 1 16 19 CFG=1
M  V30 19 1 16 20
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 2 19 23
M  V30 23 1 19 24
M  V30 24 1 9 11
M  V30 25 1 20 21
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 16)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00038001.cdx

>  <name>
US20220000056A1-20220106-C00015

>  <Row No>
15

$$$$
US20220000056A1-20220106-C00016
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2578 0.7666 0.0 0
M  V30 3 C -1.3297 0.7666 0.0 0
M  V30 4 C 1.2219 2.3 0.0 0
M  V30 5 C 2.5157 0.0359 0.0 0
M  V30 6 C -1.3656 2.3 0.0 0 CFG=2
M  V30 7 C -2.1084 -0.4911 0.0 0
M  V30 8 C -2.8631 0.8026 0.0 0
M  V30 9 C 2.4797 3.0667 0.0 0
M  V30 10 C -0.1078 3.0667 0.0 0 CFG=2
M  V30 11 C 3.7735 0.8146 0.0 0
M  V30 12 C -2.6954 3.0667 0.0 0
M  V30 13 O 2.4438 4.6001 0.0 0
M  V30 14 C 3.7376 2.348 0.0 0
M  V30 15 C -0.1437 4.6001 0.0 0
M  V30 16 C 5.0314 0.0838 0.0 0
M  V30 17 C -2.7313 4.6001 0.0 0
M  V30 18 C -1.4734 5.3788 0.0 0
M  V30 19 C 6.2892 0.8625 0.0 0
M  V30 20 C -1.5094 6.9122 0.0 0
M  V30 21 C 7.5471 0.1317 0.0 0
M  V30 22 C 8.805 0.9104 0.0 0
M  V30 23 C 10.0628 0.1796 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 3 8
M  V30 8 1 4 9
M  V30 9 1 4 10
M  V30 10 2 5 11
M  V30 11 1 6 12 CFG=1
M  V30 12 1 9 13
M  V30 13 2 9 14
M  V30 14 1 10 15 CFG=3
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 6 10
M  V30 24 1 11 14
M  V30 25 2 17 18
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 6 10)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00039001.cdx

>  <name>
US20220000056A1-20220106-C00016

>  <Row No>
16

$$$$
US20220000056A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -1.3444 -0.7388 0.0 0
M  V30 3 C 1.2717 -0.7388 0.0 0
M  V30 4 C -0.0363 1.5503 0.0 0
M  V30 5 C -1.3807 -2.2165 0.0 0
M  V30 6 C 1.2354 -2.2165 0.0 0
M  V30 7 C -0.109 -2.9553 0.0 0 CFG=1
M  V30 8 C -0.1453 -4.433 0.0 0
M  V30 9 C 1.1264 -5.1719 0.0 0
M  V30 10 C -1.4898 -5.1719 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 2 2 5
M  V30 5 1 3 6
M  V30 6 1 5 7
M  V30 7 1 7 8 CFG=1
M  V30 8 1 8 9
M  V30 9 1 8 10
M  V30 10 1 6 7
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 7)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00043001.cdx

>  <name>
US20220000056A1-20220106-C00017

>  <Row No>
17

$$$$
US20220000056A1-20220106-C00018
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -1.3482 -0.7287 0.0 0
M  V30 3 C 1.2753 -0.7287 0.0 0
M  V30 4 C -0.0364 1.5547 0.0 0
M  V30 5 C -1.3846 -2.2106 0.0 0
M  V30 6 C 1.2389 -2.2106 0.0 0
M  V30 7 C -0.0728 -1.4575 0.0 0
M  V30 8 C -0.1093 -2.9393 0.0 0
M  V30 9 C 2.5142 -2.9393 0.0 0
M  V30 10 C 2.5142 -1.4332 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 8
M  V30 11 1 7 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00044001.cdx

>  <name>
US20220000056A1-20220106-C00018

>  <Row No>
18

$$$$
US20220000056A1-20220106-C00019
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C 1.2455 0.777 0.0 0
M  V30 3 C -1.3141 0.777 0.0 0
M  V30 4 C -0.0342 -1.4398 0.0 0
M  V30 5 C -2.6283 0.0914 0.0 0
M  V30 6 C -2.0912 2.0912 0.0 0
M  V30 7 C -0.5942 2.0912 0.0 0
M  V30 8 C -1.1198 -0.3542 0.0 0
M  V30 9 C -1.3484 -2.1255 0.0 0
M  V30 10 C -2.6626 -1.3484 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 4 9
M  V30 9 1 5 10
M  V30 10 1 5 8
M  V30 11 1 9 10
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00045001.cdx

>  <name>
US20220000056A1-20220106-C00019

>  <Row No>
19

$$$$
US20220000056A1-20220106-C00020
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -0.0364 1.5547 0.0 0
M  V30 3 C 1.2753 -0.7287 0.0 0
M  V30 4 C -1.3482 -0.7287 0.0 0
M  V30 5 C 1.2389 -2.2106 0.0 0
M  V30 6 C -0.0728 -1.4575 0.0 0
M  V30 7 C -1.3846 -2.2106 0.0 0
M  V30 8 C -0.1093 -2.9393 0.0 0
M  V30 9 C 2.5142 -2.9393 0.0 0
M  V30 10 C 2.5142 -1.4332 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 1 6 8
M  V30 11 1 7 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00046001.cdx

>  <name>
US20220000056A1-20220106-C00020

>  <Row No>
20

$$$$
US20220000056A1-20220106-C00021
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 9 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C 1.2464 -0.7241 0.0 0
M  V30 3 C -0.0356 1.5194 0.0 0
M  V30 4 C -1.3176 -0.7241 0.0 0
M  V30 5 C 2.4928 0.0474 0.0 0
M  V30 6 C -2.6352 0.0474 0.0 0
M  V30 7 C -3.9528 -0.6647 0.0 0
M  V30 8 C -5.2705 0.1068 0.0 0
M  V30 9 C -6.5881 -0.6053 0.0 0
M  V30 10 C -5.3061 1.6262 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 2 2 5
M  V30 5 1 4 6
M  V30 6 1 6 7
M  V30 7 2 7 8
M  V30 8 1 8 9
M  V30 9 1 8 10
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00047001.cdx

>  <name>
US20220000056A1-20220106-C00021

>  <Row No>
21

$$$$
US20220000056A1-20220106-C00022
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C 1.2717 -0.7388 0.0 0
M  V30 3 C -1.3444 -0.7388 0.0 0
M  V30 4 C -0.0363 1.5503 0.0 0
M  V30 5 C 1.2354 -2.2165 0.0 0
M  V30 6 C -1.3807 -2.2165 0.0 0
M  V30 7 C -0.109 -2.9553 0.0 0 CFG=2
M  V30 8 C -0.1453 -4.433 0.0 0
M  V30 9 C 1.1264 -5.1719 0.0 0
M  V30 10 C -1.4898 -5.1719 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 5 7
M  V30 7 1 7 8 CFG=1
M  V30 8 2 8 9
M  V30 9 1 8 10
M  V30 10 1 6 7
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 7)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00048001.cdx

>  <name>
US20220000056A1-20220106-C00022

>  <Row No>
22

$$$$
US20220000056A1-20220106-C00023
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -0.0353 -1.4844 0.0 0
M  V30 3 C 1.2841 0.7893 0.0 0
M  V30 4 C -1.3548 0.7893 0.0 0
M  V30 5 C 1.2488 -2.1913 0.0 0
M  V30 6 C 2.5683 0.0824 0.0 0
M  V30 7 C 2.5329 -1.4019 0.0 0
M  V30 8 C 3.8524 -0.6244 0.0 0
M  V30 9 C 5.3368 -0.589 0.0 0
M  V30 10 C 4.5711 0.7304 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 8 10
M  V30 10 1 6 7
M  V30 11 1 7 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00049001.cdx

>  <name>
US20220000056A1-20220106-C00023

>  <Row No>
23

$$$$
US20220000056A1-20220106-C00024
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 2.392 -1.5377 0.0 0
M  V30 3 C 0.3986 0.6644 0.0 0
M  V30 4 C 3.7968 -1.9364 0.0 0
M  V30 5 C 1.101 -2.0123 0.0 0
M  V30 6 C 1.6326 -2.6768 0.0 0
M  V30 7 C 1.5187 -0.1328 0.0 0
M  V30 8 C -0.3607 1.9553 0.0 0
M  V30 9 C 1.0441 1.9553 0.0 0
M  V30 10 C 3.0185 -0.7783 0.0 0
M  V30 11 C 0.3227 -0.7403 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 3 8
M  V30 8 1 3 9
M  V30 9 1 4 10
M  V30 10 1 5 11
M  V30 11 1 7 10
M  V30 12 1 7 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00050001.cdx

>  <name>
US20220000056A1-20220106-C00024

>  <Row No>
24

$$$$
US20220000056A1-20220106-C00025
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -1.3241 0.7634 0.0 0
M  V30 3 C -0.0357 -1.4553 0.0 0
M  V30 4 C 1.2525 0.7634 0.0 0
M  V30 5 C -1.3598 2.2903 0.0 0
M  V30 6 C 1.2167 -2.1829 0.0 0
M  V30 7 C -1.3598 -2.1829 0.0 0
M  V30 8 C 1.2167 2.2903 0.0 0
M  V30 9 C -0.1073 3.0657 0.0 0
M  V30 10 C -0.1431 4.5926 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 2 8 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00051001.cdx

>  <name>
US20220000056A1-20220106-C00025

>  <Row No>
25

$$$$
US20220000056A1-20220106-C00026
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2773 0.8086 0.0 0 CFG=2
M  V30 3 C 0.4687 2.1563 0.0 0
M  V30 4 C 2.5547 1.6055 0.0 0
M  V30 5 C 2.0156 -0.4687 0.0 0
M  V30 6 C 1.1953 3.504 0.0 0
M  V30 7 C 3.8321 0.9023 0.0 0
M  V30 8 C 5.1095 1.6992 0.0 0
M  V30 9 C 6.3869 0.9961 0.0 0
M  V30 10 C 7.6643 1.793 0.0 0
M  V30 11 C 6.3517 -0.4804 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=3
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 3 6
M  V30 6 1 4 7
M  V30 7 1 7 8
M  V30 8 2 8 9
M  V30 9 1 9 10
M  V30 10 1 9 11
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00052001.cdx

>  <name>
US20220000056A1-20220106-C00026

>  <Row No>
26

$$$$
US20220000056A1-20220106-C00027
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 15 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -0.0357 -1.453 0.0 0
M  V30 3 C -1.322 0.7622 0.0 0
M  V30 4 C 1.2506 0.7622 0.0 0
M  V30 5 C 1.2148 -2.1796 0.0 0
M  V30 6 C -1.3578 -2.1796 0.0 0
M  V30 7 C -1.3578 2.2868 0.0 0 CFG=2
M  V30 8 C 1.2148 2.2868 0.0 0
M  V30 9 C -2.6798 3.061 0.0 0
M  V30 10 C -0.1071 3.061 0.0 0 CFG=2
M  V30 11 C -2.7156 4.5855 0.0 0
M  V30 12 C -4.0019 2.3344 0.0 0
M  V30 13 C 0.6074 4.383 0.0 0
M  V30 14 C -0.8694 4.383 0.0 0
M  V30 15 C 2.0605 4.4188 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 7 9 CFG=3
M  V30 9 1 7 10
M  V30 10 2 9 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 10 14 CFG=3
M  V30 14 2 13 15
M  V30 15 1 8 10
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 7 10)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00053001.cdx

>  <name>
US20220000056A1-20220106-C00027

>  <Row No>
27

$$$$
US20220000056A1-20220106-C00028
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 15 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -0.7645 -1.2543 0.0 0
M  V30 3 C -0.7645 1.326 0.0 0
M  V30 4 C 1.4574 0.0358 0.0 0
M  V30 5 C 0.4061 -2.0906 0.0 0
M  V30 6 C -2.2937 1.3618 0.0 0
M  V30 7 C -0.0955 -3.4764 0.0 0
M  V30 8 C -3.0582 0.1075 0.0 0
M  V30 9 C -1.6247 -3.4405 0.0 0
M  V30 10 C -4.0617 -0.2986 0.0 0
M  V30 11 C -2.1264 -1.9831 0.0 0
M  V30 12 C -2.4012 -4.6949 0.0 0
M  V30 13 C -4.0976 -1.7561 0.0 0
M  V30 14 C -4.0976 1.2304 0.0 0
M  V30 15 C -5.3878 0.4659 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 2 9 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 1 10 15
M  V30 15 1 11 13
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00054001.cdx

>  <name>
US20220000056A1-20220106-C00028

>  <Row No>
28

$$$$
US20220000056A1-20220106-C00029
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 15 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2835 0.8124 0.0 0 CFG=2
M  V30 3 C 0.471 2.1666 0.0 0
M  V30 4 C 2.567 1.6132 0.0 0
M  V30 5 C 1.99 -0.471 0.0 0
M  V30 6 C 1.2128 3.5208 0.0 0
M  V30 7 C 3.8505 0.9066 0.0 0
M  V30 8 C 5.134 1.7074 0.0 0
M  V30 9 C 6.4175 1.0008 0.0 0
M  V30 10 C 7.701 1.8016 0.0 0
M  V30 11 C 6.3821 -0.4827 0.0 0
M  V30 12 C 8.9845 1.095 0.0 0
M  V30 13 C 10.268 1.8958 0.0 0
M  V30 14 C 11.5515 1.1893 0.0 0
M  V30 15 C 12.835 1.99 0.0 0
M  V30 16 C 11.5162 -0.2943 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=3
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 3 6
M  V30 6 1 4 7
M  V30 7 1 7 8
M  V30 8 2 8 9
M  V30 9 1 9 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00055001.cdx

>  <name>
US20220000056A1-20220106-C00029

>  <Row No>
29

$$$$
US20220000056A1-20220106-C00030
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 16 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C 0.9122 1.2162 0.0 0
M  V30 3 C 0.2923 -1.4384 0.0 0
M  V30 4 C -1.4969 0.421 0.0 0
M  V30 5 C 2.3857 1.2513 0.0 0
M  V30 6 C 0.421 2.6898 0.0 0
M  V30 7 C 1.6139 -2.0466 0.0 0
M  V30 8 C 2.8067 2.7249 0.0 0
M  V30 9 C 3.2979 0.1052 0.0 0
M  V30 10 C 1.6139 3.6254 0.0 0
M  V30 11 C 2.9354 -1.3683 0.0 0 CFG=1
M  V30 12 C 4.0815 3.5318 0.0 0
M  V30 13 C 4.2101 -2.105 0.0 0
M  V30 14 C 5.4849 -1.2981 0.0 0
M  V30 15 C 4.1751 -3.5786 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 11 13 CFG=1
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 15 1 8 10
M  V30 16 1 9 11
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 11)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00056001.cdx

>  <name>
US20220000056A1-20220106-C00030

>  <Row No>
30

$$$$
US20220000056A1-20220106-C00031
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 16 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -1.3372 -0.6589 0.0 0
M  V30 3 C 1.1822 -0.6589 0.0 0 CFG=1
M  V30 4 C -0.0581 1.5116 0.0 0
M  V30 5 C 3.6241 -0.6007 0.0 0 CFG=1
M  V30 6 C 1.4923 -2.0155 0.0 0
M  V30 7 C 1.124 2.2869 0.0 0
M  V30 8 C 3.1978 -1.9574 0.0 0
M  V30 9 C 4.8451 0.1744 0.0 0
M  V30 10 C 2.2869 1.6279 0.0 0
M  V30 11 C 4.3218 -1.531 0.0 0
M  V30 12 C 4.1474 -2.907 0.0 0
M  V30 13 C 4.787 1.6861 0.0 0
M  V30 14 C 3.5078 2.4031 0.0 0
M  V30 15 C 3.4497 3.9148 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 3 1 CFG=1
M  V30 3 1 1 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9 CFG=3
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 14 15
M  V30 15 1 6 8
M  V30 16 1 13 14
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 3 5)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00057001.cdx

>  <name>
US20220000056A1-20220106-C00031

>  <Row No>
31

$$$$
US20220000102A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 4 3 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2932 -0.7389 0.0 0
M  V30 3 C 2.5864 0.0615 0.0 0
M  V30 4 O 3.8797 -0.6774 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000102A1-20220106-C00001

>  <Row No>
32

$$$$
US20220000103A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 235 235 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.6665 0.1666 0.0 0
M  V30 3 O -2.7221 -0.8888 0.0 0
M  V30 4 C -2.7221 1.5554 0.0 0
M  V30 5 C -4.2775 -0.2777 0.0 0 CFG=2
M  V30 6 C -4.2775 1.2777 0.0 0
M  V30 7 C -5.7219 -0.8332 0.0 0
M  V30 8 C -4.2775 -1.611 0.0 0
M  V30 9 C -5.7219 2.1665 0.0 0
M  V30 10 C -7.1663 0.0555 0.0 0
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M  V30 17 C -5.1664 -51.2199 0.0 0
M  V30 18 C -5.333 -52.5532 0.0 0
M  V30 19 C -6.6108 -50.3311 0.0 0
M  V30 20 C -6.7774 -53.1087 0.0 0
M  V30 21 C -4.222 -53.1087 0.0 0
M  V30 22 C -8.0551 -50.8866 0.0 0
M  V30 23 C -7.4996 -48.8867 0.0 0
M  V30 24 C -6.3886 -48.72 0.0 0
M  V30 25 C -8.2218 -52.2199 0.0 0
M  V30 26 O -3.5553 -42.2203 0.0 0
M  V30 27 C -3.722 -43.5536 0.0 0
M  V30 28 O -2.6109 -44.1091 0.0 0
M  V30 29 C -5.1664 -44.1091 0.0 0
M  V30 30 C -5.333 -45.4424 0.0 0
M  V30 31 C -6.6108 -43.2203 0.0 0
M  V30 32 C -6.7774 -45.9979 0.0 0
M  V30 33 C -4.222 -45.9979 0.0 0
M  V30 34 C -8.0551 -43.7758 0.0 0
M  V30 35 C -7.4996 -41.7759 0.0 0
M  V30 36 C -6.3886 -41.6092 0.0 0
M  V30 37 C -8.2218 -45.1091 0.0 0
M  V30 38 O -3.5553 -55.9975 0.0 0
M  V30 39 C -3.722 -57.3307 0.0 0
M  V30 40 O -2.6109 -57.8863 0.0 0
M  V30 41 C -5.1664 -57.8863 0.0 0
M  V30 42 C -5.333 -59.2195 0.0 0
M  V30 43 C -6.6108 -56.9974 0.0 0
M  V30 44 C -6.7774 -59.7751 0.0 0
M  V30 45 C -4.222 -59.7751 0.0 0
M  V30 46 C -8.0551 -57.553 0.0 0
M  V30 47 C -6.7774 -55.3308 0.0 0
M  V30 48 C -8.2218 -58.8862 0.0 0
M  V30 49 O -1.7776 35.9984 0.0 0
M  V30 50 C -1.9443 34.6651 0.0 0
M  V30 51 C -3.3887 34.1095 0.0 0
M  V30 52 C -0.8332 34.1095 0.0 0
M  V30 53 C -4.8331 34.9984 0.0 0
M  V30 54 C -6.2774 34.4429 0.0 0
M  V30 55 C -6.4441 33.1096 0.0 0
M  V30 56 C -7.7218 35.3317 0.0 0
M  V30 57 C -7.8885 32.5541 0.0 0
M  V30 58 C -5.333 32.5541 0.0 0
M  V30 59 C -9.1662 34.7762 0.0 0
M  V30 60 C -8.6107 36.7761 0.0 0
M  V30 61 C -7.1663 36.7761 0.0 0
M  V30 62 C -9.3329 33.4429 0.0 0
M  V30 63 O 2.6665 -11.1106 0.0 0
M  V30 64 C 1.2221 -10.2217 0.0 0
M  V30 65 C -0.2222 -10.7772 0.0 0
M  V30 66 C 1.0555 -8.5551 0.0 0
M  V30 67 C -1.6665 -9.8884 0.0 0
M  V30 68 C -3.1109 -10.4439 0.0 0
M  V30 69 C -4.5553 -9.5551 0.0 0
M  V30 70 C -5.9997 -10.1106 0.0 0
M  V30 71 C -4.722 -7.8885 0.0 0
M  V30 72 C -7.4441 -9.2218 0.0 0
M  V30 73 C -8.8884 -9.7773 0.0 0
M  V30 74 C -10.3328 -8.8884 0.0 0
M  V30 75 C -11.7772 -9.444 0.0 0
M  V30 76 C -10.4995 -7.2219 0.0 0
M  V30 77 C -13.2216 -8.5551 0.0 0
M  V30 78 O -1.7776 -2.2221 0.0 0
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M  V30 81 C -0.8332 -4.1109 0.0 0
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M  V30 87 C -5.333 -5.6664 0.0 0
M  V30 88 C -9.1662 -3.4442 0.0 0
M  V30 89 C -8.6107 -1.4443 0.0 0
M  V30 90 C -7.1663 -1.4443 0.0 0
M  V30 91 C -9.3329 -4.7775 0.0 0
M  V30 92 O -1.7776 17.3325 0.0 0
M  V30 93 C -1.9443 15.9992 0.0 0
M  V30 94 C -3.3887 15.4437 0.0 0
M  V30 95 C -0.8332 15.4437 0.0 0
M  V30 96 C -4.8331 16.3326 0.0 0
M  V30 97 C -6.2774 15.777 0.0 0
M  V30 98 C -6.4441 14.4438 0.0 0
M  V30 99 C -7.7218 16.6659 0.0 0
M  V30 100 C -7.8885 13.8882 0.0 0
M  V30 101 C -5.333 13.8882 0.0 0
M  V30 102 C -9.1662 16.1103 0.0 0
M  V30 103 C -8.6107 18.1103 0.0 0
M  V30 104 C -7.1663 18.1103 0.0 0
M  V30 105 C -9.3329 14.7771 0.0 0
M  V30 106 O -3.1109 23.11 0.0 0
M  V30 107 C -3.2776 21.7768 0.0 0
M  V30 108 C -4.722 21.2212 0.0 0
M  V30 109 C -4.8886 19.888 0.0 0
M  V30 110 C -6.1663 22.1101 0.0 0
M  V30 111 C -6.333 19.3324 0.0 0
M  V30 112 C -3.7776 19.3324 0.0 0
M  V30 113 C -7.6107 21.5545 0.0 0
M  V30 114 C -7.0552 23.5545 0.0 0
M  V30 115 C -5.6108 23.5545 0.0 0
M  V30 116 C -7.7774 20.2213 0.0 0
M  V30 117 O -3.1109 30.2208 0.0 0
M  V30 118 C -3.2776 28.8876 0.0 0
M  V30 119 C -4.722 28.332 0.0 0
M  V30 120 C -4.8886 26.9988 0.0 0
M  V30 121 C -6.1663 29.2209 0.0 0
M  V30 122 C -6.333 26.4432 0.0 0
M  V30 123 C -3.7776 26.4432 0.0 0
M  V30 124 C -7.6107 28.6653 0.0 0
M  V30 125 C -7.0552 30.6653 0.0 0
M  V30 126 C -5.6108 30.6653 0.0 0
M  V30 127 C -7.7774 27.3321 0.0 0
M  V30 128 O -3.1109 10.6661 0.0 0
M  V30 129 C -3.2776 9.3329 0.0 0
M  V30 130 C -4.722 8.7773 0.0 0
M  V30 131 C -4.8886 7.4441 0.0 0
M  V30 132 C -6.1663 9.6662 0.0 0
M  V30 133 C -6.333 6.8885 0.0 0
M  V30 134 C -3.7776 6.8885 0.0 0
M  V30 135 C -7.6107 9.1107 0.0 0
M  V30 136 C -6.333 11.3328 0.0 0
M  V30 137 C -7.7774 7.7774 0.0 0
M  V30 138 O 3.9998 -21.3323 0.0 0
M  V30 139 C 3.8331 -22.5545 0.0 0
M  V30 140 C 2.4998 -23.0545 0.0 0
M  V30 141 C 1.1666 -22.2212 0.0 0
M  V30 142 C 2.3332 -24.2767 0.0 0
M  V30 143 C -0.1666 -22.7212 0.0 0
M  V30 144 C -1.4999 -21.8879 0.0 0
M  V30 145 C -2.8332 -22.3878 0.0 0
M  V30 146 C -4.1664 -21.5545 0.0 0
M  V30 147 C -5.4997 -22.0545 0.0 0
M  V30 148 C -4.3331 -19.9991 0.0 0
M  V30 149 C -6.833 -21.2212 0.0 0
M  V30 150 C -8.1663 -21.7212 0.0 0
M  V30 151 C -9.4995 -20.8879 0.0 0
M  V30 152 C -10.8328 -21.3879 0.0 0
M  V30 153 C -9.6662 -19.3324 0.0 0
M  V30 154 C -12.1661 -20.5546 0.0 0
M  V30 155 C -13.4994 -21.0546 0.0 0
M  V30 156 C -13.666 -22.2767 0.0 0
M  V30 157 C -14.8326 -20.2213 0.0 0
M  V30 158 C -14.9993 -22.7767 0.0 0
M  V30 159 C -12.6661 -22.7767 0.0 0
M  V30 160 C -16.1659 -20.7213 0.0 0
M  V30 161 C -15.6659 -18.888 0.0 0
M  V30 162 C -14.666 -18.7213 0.0 0
M  V30 163 C -16.3326 -21.9434 0.0 0
M  V30 164 O 3.1109 -37.7761 0.0 0
M  V30 165 C 1.6665 -36.8872 0.0 0
M  V30 166 C 0.2222 -37.4427 0.0 0
M  V30 167 C -1.2221 -36.5539 0.0 0
M  V30 168 C -2.6665 -37.1094 0.0 0
M  V30 169 C -1.3888 -34.8873 0.0 0
M  V30 170 C -4.1109 -36.2206 0.0 0
M  V30 171 C -5.5553 -36.7761 0.0 0
M  V30 172 C -6.9996 -35.8872 0.0 0
M  V30 173 C -8.444 -36.4428 0.0 0
M  V30 174 C -7.1663 -34.2207 0.0 0
M  V30 175 C -9.8884 -35.5539 0.0 0
M  V30 176 C -11.3328 -36.1095 0.0 0
M  V30 177 C -11.4994 -37.4427 0.0 0
M  V30 178 C -12.7772 -35.2206 0.0 0
M  V30 179 C -12.9438 -37.9983 0.0 0
M  V30 180 C -10.3884 -37.9983 0.0 0
M  V30 181 C -14.2215 -35.7761 0.0 0
M  V30 182 C -13.666 -33.7762 0.0 0
M  V30 183 C -12.5549 -33.6096 0.0 0
M  V30 184 C -14.3882 -37.1094 0.0 0
M  V30 185 O 3.9998 -14.666 0.0 0
M  V30 186 C 3.8331 -15.7215 0.0 0
M  V30 187 C 2.6109 -16.1659 0.0 0
M  V30 188 C 1.3888 -15.3882 0.0 0
M  V30 189 C 0.1666 -15.8326 0.0 0
M  V30 190 C -1.0555 -15.0548 0.0 0
M  V30 191 C 0.0 -16.8881 0.0 0
M  V30 192 C -2.2776 -15.4993 0.0 0
M  V30 193 C -3.4998 -14.7215 0.0 0
M  V30 194 C -4.722 -15.1659 0.0 0
M  V30 195 C -5.9441 -14.3882 0.0 0
M  V30 196 C -7.1663 -14.8326 0.0 0
M  V30 197 C -6.1108 -12.9994 0.0 0
M  V30 198 C -8.3885 -14.0549 0.0 0
M  V30 199 C -9.6106 -14.4993 0.0 0
M  V30 200 C -10.8328 -13.7216 0.0 0
M  V30 201 C -12.055 -14.166 0.0 0
M  V30 202 C -10.9995 -12.3327 0.0 0
M  V30 203 C -13.2771 -13.3882 0.0 0
M  V30 204 C -14.4993 -13.8327 0.0 0
M  V30 205 C -14.666 -14.8882 0.0 0
M  V30 206 C -15.7215 -13.0549 0.0 0
M  V30 207 C -15.8881 -15.3326 0.0 0
M  V30 208 C -13.7771 -15.3326 0.0 0
M  V30 209 C -16.9436 -13.4994 0.0 0
M  V30 210 C -16.4992 -11.8328 0.0 0
M  V30 211 C -15.5548 -11.7217 0.0 0
M  V30 212 C -17.1103 -14.5549 0.0 0
M  V30 213 O 3.1109 -28.8876 0.0 0
M  V30 214 C 2.9443 -30.2208 0.0 0
M  V30 215 C 1.4999 -30.7764 0.0 0
M  V30 216 C 0.0555 -29.8875 0.0 0
M  V30 217 C -1.3888 -30.443 0.0 0
M  V30 218 C -2.8332 -29.5542 0.0 0
M  V30 219 C -4.2775 -30.1097 0.0 0
M  V30 220 C -2.9998 -27.8876 0.0 0
M  V30 221 C -5.7219 -29.2209 0.0 0
M  V30 222 C -7.1663 -29.7764 0.0 0
M  V30 223 C -8.6107 -28.8876 0.0 0
M  V30 224 C -10.0551 -29.4431 0.0 0
M  V30 225 C -8.7773 -27.221 0.0 0
M  V30 226 C -11.4994 -28.5542 0.0 0
M  V30 227 C -12.9438 -29.1098 0.0 0
M  V30 228 C -13.1105 -30.443 0.0 0
M  V30 229 C -14.3882 -28.2209 0.0 0
M  V30 230 C -14.5549 -30.9986 0.0 0
M  V30 231 C -11.9994 -30.9986 0.0 0
M  V30 232 C -15.8326 -28.7765 0.0 0
M  V30 233 C -15.2771 -26.7765 0.0 0
M  V30 234 C -14.166 -26.6099 0.0 0
M  V30 235 C -15.9992 -30.1097 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8 CFG=3
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 9 13
M  V30 13 2 14 15
M  V30 14 1 15 16
M  V30 15 1 15 17
M  V30 16 2 17 18
M  V30 17 1 17 19
M  V30 18 1 18 20
M  V30 19 1 18 21
M  V30 20 1 19 22
M  V30 21 1 19 23
M  V30 22 1 19 24
M  V30 23 2 20 25
M  V30 24 2 26 27
M  V30 25 1 27 28
M  V30 26 1 27 29
M  V30 27 2 29 30
M  V30 28 1 29 31
M  V30 29 1 30 32
M  V30 30 1 30 33
M  V30 31 1 31 34
M  V30 32 1 31 35
M  V30 33 1 31 36
M  V30 34 1 32 37
M  V30 35 2 38 39
M  V30 36 1 39 40
M  V30 37 1 39 41
M  V30 38 2 41 42
M  V30 39 1 41 43
M  V30 40 1 42 44
M  V30 41 1 42 45
M  V30 42 1 43 46
M  V30 43 1 43 47
M  V30 44 2 44 48
M  V30 45 2 49 50
M  V30 46 1 50 51
M  V30 47 1 50 52
M  V30 48 2 51 53
M  V30 49 1 53 54
M  V30 50 2 54 55
M  V30 51 1 54 56
M  V30 52 1 55 57
M  V30 53 1 55 58
M  V30 54 1 56 59
M  V30 55 1 56 60
M  V30 56 1 56 61
M  V30 57 1 57 62
M  V30 58 2 63 64
M  V30 59 1 64 65
M  V30 60 1 64 66
M  V30 61 2 65 67
M  V30 62 1 67 68
M  V30 63 2 68 69
M  V30 64 1 69 70
M  V30 65 1 69 71
M  V30 66 1 70 72
M  V30 67 1 72 73
M  V30 68 2 73 74
M  V30 69 1 74 75
M  V30 70 1 74 76
M  V30 71 1 75 77
M  V30 72 2 78 79
M  V30 73 1 79 80
M  V30 74 1 79 81
M  V30 75 2 80 82
M  V30 76 1 82 83
M  V30 77 1 83 84
M  V30 78 1 83 85
M  V30 79 2 84 86
M  V30 80 1 84 87
M  V30 81 1 85 88
M  V30 82 1 85 89
M  V30 83 1 85 90
M  V30 84 1 86 91
M  V30 85 2 92 93
M  V30 86 1 93 94
M  V30 87 1 93 95
M  V30 88 1 94 96
M  V30 89 1 96 97
M  V30 90 2 97 98
M  V30 91 1 97 99
M  V30 92 1 98 100
M  V30 93 1 98 101
M  V30 94 1 99 102
M  V30 95 1 99 103
M  V30 96 1 99 104
M  V30 97 1 100 105
M  V30 98 2 106 107
M  V30 99 1 107 108
M  V30 100 2 108 109
M  V30 101 1 108 110
M  V30 102 1 109 111
M  V30 103 1 109 112
M  V30 104 1 110 113
M  V30 105 1 110 114
M  V30 106 1 110 115
M  V30 107 2 111 116
M  V30 108 2 117 118
M  V30 109 1 118 119
M  V30 110 2 119 120
M  V30 111 1 119 121
M  V30 112 1 120 122
M  V30 113 1 120 123
M  V30 114 1 121 124
M  V30 115 1 121 125
M  V30 116 1 121 126
M  V30 117 1 122 127
M  V30 118 2 128 129
M  V30 119 1 129 130
M  V30 120 2 130 131
M  V30 121 1 130 132
M  V30 122 1 131 133
M  V30 123 1 131 134
M  V30 124 1 132 135
M  V30 125 1 132 136
M  V30 126 1 133 137
M  V30 127 2 138 139
M  V30 128 1 139 140
M  V30 129 2 140 141
M  V30 130 1 140 142
M  V30 131 1 141 143
M  V30 132 2 143 144
M  V30 133 1 144 145
M  V30 134 2 145 146
M  V30 135 1 146 147
M  V30 136 1 146 148
M  V30 137 2 147 149
M  V30 138 1 149 150
M  V30 139 2 150 151
M  V30 140 1 151 152
M  V30 141 1 151 153
M  V30 142 2 152 154
M  V30 143 1 154 155
M  V30 144 2 155 156
M  V30 145 1 155 157
M  V30 146 1 156 158
M  V30 147 1 156 159
M  V30 148 1 157 160
M  V30 149 1 157 161
M  V30 150 1 157 162
M  V30 151 1 158 163
M  V30 152 2 164 165
M  V30 153 1 165 166
M  V30 154 2 166 167
M  V30 155 1 167 168
M  V30 156 1 167 169
M  V30 157 2 168 170
M  V30 158 1 170 171
M  V30 159 2 171 172
M  V30 160 1 172 173
M  V30 161 1 172 174
M  V30 162 2 173 175
M  V30 163 1 175 176
M  V30 164 2 176 177
M  V30 165 1 176 178
M  V30 166 1 177 179
M  V30 167 1 177 180
M  V30 168 1 178 181
M  V30 169 1 178 182
M  V30 170 1 178 183
M  V30 171 1 179 184
M  V30 172 2 185 186
M  V30 173 1 186 187
M  V30 174 2 187 188
M  V30 175 1 188 189
M  V30 176 2 189 190
M  V30 177 1 189 191
M  V30 178 1 190 192
M  V30 179 2 192 193
M  V30 180 1 193 194
M  V30 181 2 194 195
M  V30 182 1 195 196
M  V30 183 1 195 197
M  V30 184 2 196 198
M  V30 185 1 198 199
M  V30 186 2 199 200
M  V30 187 1 200 201
M  V30 188 1 200 202
M  V30 189 2 201 203
M  V30 190 1 203 204
M  V30 191 2 204 205
M  V30 192 1 204 206
M  V30 193 1 205 207
M  V30 194 1 205 208
M  V30 195 1 206 209
M  V30 196 1 206 210
M  V30 197 1 206 211
M  V30 198 1 207 212
M  V30 199 2 213 214
M  V30 200 1 214 215
M  V30 201 2 215 216
M  V30 202 1 216 217
M  V30 203 2 217 218
M  V30 204 1 218 219
M  V30 205 1 218 220
M  V30 206 2 219 221
M  V30 207 1 221 222
M  V30 208 2 222 223
M  V30 209 1 223 224
M  V30 210 1 223 225
M  V30 211 2 224 226
M  V30 212 1 226 227
M  V30 213 2 227 228
M  V30 214 1 227 229
M  V30 215 1 228 230
M  V30 216 1 228 231
M  V30 217 1 229 232
M  V30 218 1 229 233
M  V30 219 1 229 234
M  V30 220 1 230 235
M  V30 221 1 5 6
M  V30 222 1 10 11
M  V30 223 1 22 25
M  V30 224 1 34 37
M  V30 225 1 46 48
M  V30 226 1 59 62
M  V30 227 1 88 91
M  V30 228 1 102 105
M  V30 229 1 113 116
M  V30 230 1 124 127
M  V30 231 1 135 137
M  V30 232 1 160 163
M  V30 233 1 181 184
M  V30 234 1 209 212
M  V30 235 1 232 235
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 5)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000103A1-20220106-C00001

>  <Row No>
33

$$$$
US20220000106A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 33 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.045 -1.427 0.0 0
M  V30 3 O 1.1867 -2.1331 0.0 0
M  V30 4 C -1.3669 -2.1331 0.0 0
M  V30 5 C -2.6889 -1.3369 0.0 0
M  V30 6 C -4.0108 -2.0429 0.0 0
M  V30 7 C -5.3327 -1.2468 0.0 0
M  V30 8 C -6.6546 -1.9528 0.0 0
M  V30 9 C -7.9766 -1.1566 0.0 0
M  V30 10 C -9.2985 -1.8627 0.0 0
M  V30 11 C -10.6204 -1.0665 0.0 0
M  V30 12 C -11.9423 -1.7725 0.0 0
M  V30 13 O -1.6824 8.292 0.0 0
M  V30 14 C -1.7275 6.8649 0.0 0
M  V30 15 O -0.4957 6.1589 0.0 0
M  V30 16 C -3.0494 6.1589 0.0 0
M  V30 17 C -4.3713 6.9551 0.0 0
M  V30 18 C -5.6932 6.249 0.0 0
M  V30 19 C -7.0152 7.0452 0.0 0
M  V30 20 C -8.3371 6.3392 0.0 0
M  V30 21 C -9.659 7.1353 0.0 0
M  V30 22 C -10.9809 6.4293 0.0 0
M  V30 23 C -12.3029 7.2255 0.0 0
M  V30 24 O -3.0043 15.3823 0.0 0
M  V30 25 C -3.0494 13.9553 0.0 0
M  V30 26 O -1.8176 13.2492 0.0 0
M  V30 27 C -4.3713 13.2492 0.0 0
M  V30 28 C -5.6932 14.0454 0.0 0
M  V30 29 C -7.0152 13.3394 0.0 0
M  V30 30 C -8.3371 14.1355 0.0 0
M  V30 31 C -9.659 13.4295 0.0 0
M  V30 32 C -10.9809 14.2257 0.0 0
M  V30 33 C -12.3029 13.5196 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 4 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 2 13 14
M  V30 13 1 14 15
M  V30 14 1 14 16
M  V30 15 1 16 17
M  V30 16 1 17 18
M  V30 17 1 18 19
M  V30 18 1 19 20
M  V30 19 1 20 21
M  V30 20 1 21 22
M  V30 21 1 22 23
M  V30 22 2 24 25
M  V30 23 1 25 26
M  V30 24 1 25 27
M  V30 25 1 27 28
M  V30 26 1 28 29
M  V30 27 1 29 30
M  V30 28 1 30 31
M  V30 29 1 31 32
M  V30 30 1 32 33
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000106A1-20220106-C00001

>  <Row No>
34

$$$$
US20220000106A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 P 0.0 0.0 0.0 0
M  V30 2 O -0.0364 1.5545 0.0 0
M  V30 3 O -0.0364 -1.4817 0.0 0
M  V30 4 C 1.2752 -0.7287 0.0 0
M  V30 5 C -1.3481 -0.7287 0.0 0
M  V30 6 C 2.5504 0.0485 0.0 0
M  V30 7 C 3.8257 -0.6801 0.0 0
M  V30 8 N 3.7892 -2.1618 0.0 0
M  V30 9 C 5.1009 0.0971 0.0 0
M  V30 10 O 5.0645 1.6517 0.0 0
M  V30 11 O 6.3762 -0.6315 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000106A1-20220106-C00002

>  <Row No>
35

$$$$
US20220000108A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 2 1 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C 1.4995 0.0357 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000108A1-20220106-C00001

>  <Row No>
36

$$$$
US20220000108A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000108A1-20220106-C00002

>  <Row No>
37

$$$$
US20220000108A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 3 2 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 O 0.718 -1.2805 0.0 0
M  V30 3 ? -1.5318 0.0119 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000108A1-20220106-C00003

>  <Row No>
38

$$$$
US20220000108A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000108A1-20220106-C00004

>  <Row No>
39

$$$$
US20220000109A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 N 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000109A1-20220106-C00002

>  <Row No>
40

$$$$
US20220000109A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 C 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000109A1-20220106-C00003

>  <Row No>
41

$$$$
US20220000109A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 N 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000109A1-20220106-C00005

>  <Row No>
42

$$$$
US20220000109A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 C 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000109A1-20220106-C00006

>  <Row No>
43

$$$$
US20220000109A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.5781 1.3805 0.0 0
M  V30 3 O 2.0059 1.5693 0.0 0
M  V30 4 C -0.3185 2.6077 0.0 0
M  V30 5 N 0.1061 4.0472 0.0 0
M  V30 6 C -1.8289 2.6431 0.0 0
M  V30 7 O -1.1209 4.944 0.0 0
M  V30 8 C -2.3245 4.0826 0.0 0
M  V30 9 C -3.7876 3.7286 0.0 0
M  V30 10 C -2.5959 5.593 0.0 0
M  V30 11 C -4.8614 4.8024 0.0 0
M  V30 12 C -4.2124 2.3363 0.0 0
M  V30 13 C -1.4867 6.5488 0.0 0
M  V30 14 C -4.0118 6.1712 0.0 0
M  V30 15 C -6.3246 4.4484 0.0 0
M  V30 16 C -5.6756 1.9823 0.0 0
M  V30 17 C -1.7581 8.0355 0.0 0
M  V30 18 C -4.2832 7.6579 0.0 0
M  V30 19 C -6.7494 3.0561 0.0 0
M  V30 20 C -3.1741 8.6137 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 8 10
M  V30 10 2 9 11
M  V30 11 1 9 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 2 12 16
M  V30 16 1 13 17
M  V30 17 2 14 18
M  V30 18 2 15 19
M  V30 19 2 17 20
M  V30 20 1 7 8
M  V30 21 1 16 19
M  V30 22 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000109A1-20220106-C00007

>  <Row No>
44

$$$$
US20220000109A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.5804 1.3859 0.0 0
M  V30 3 O 2.0137 1.5754 0.0 0
M  V30 4 C -0.3198 2.6178 0.0 0
M  V30 5 C 2.8784 0.4501 0.0 0
M  V30 6 N 0.1066 4.0629 0.0 0
M  V30 7 C -1.836 2.6533 0.0 0
M  V30 8 C 4.3117 0.687 0.0 0
M  V30 9 O -1.1253 4.9632 0.0 0
M  V30 10 C -2.3335 4.0985 0.0 0
M  V30 11 C -3.8023 3.7431 0.0 0
M  V30 12 C -2.6059 5.6147 0.0 0
M  V30 13 C -4.8803 4.821 0.0 0
M  V30 14 C -4.2288 2.3453 0.0 0
M  V30 15 C -1.4925 6.5742 0.0 0
M  V30 16 C -4.0274 6.1951 0.0 0
M  V30 17 C -6.3491 4.4657 0.0 0
M  V30 18 C -5.6976 1.99 0.0 0
M  V30 19 C -1.7649 8.0667 0.0 0
M  V30 20 C -4.2998 7.6876 0.0 0
M  V30 21 C -6.7755 3.0679 0.0 0
M  V30 22 C -3.1864 8.6471 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 10 11
M  V30 11 1 10 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 2 14 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 2 17 21
M  V30 21 2 19 22
M  V30 22 1 9 10
M  V30 23 1 18 21
M  V30 24 1 20 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000109A1-20220106-C00008

>  <Row No>
45

$$$$
US20220000109A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 C 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000109A1-20220106-C00010

>  <Row No>
46

$$$$
US20220000109A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 C 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00038001.cdx

>  <name>
US20220000109A1-20220106-C00011

>  <Row No>
47

$$$$
US20220000109A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 C 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00040001.cdx

>  <name>
US20220000109A1-20220106-C00013

>  <Row No>
48

$$$$
US20220000109A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 C 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00041001.cdx

>  <name>
US20220000109A1-20220106-C00014

>  <Row No>
49

$$$$
US20220000110A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3695 -0.6607 0.0 0
M  V30 3 C -2.7031 0.1201 0.0 0
M  V30 4 C -1.4056 -2.1264 0.0 0
M  V30 5 N -2.7151 1.6579 0.0 0
M  V30 6 C -4.0366 -0.5886 0.0 0
M  V30 7 N -2.7391 -2.8473 0.0 0
M  V30 8 C -0.1201 -2.8232 0.0 0
M  V30 9 F -5.3942 0.1561 0.0 0
M  V30 10 C -4.0727 -2.0543 0.0 0
M  V30 11 O -0.1201 -4.2889 0.0 0
M  V30 12 O 1.1413 -2.0423 0.0 0
M  V30 13 C -5.3942 -2.7872 0.0 0
M  V30 14 C 2.4027 -2.7632 0.0 0
M  V30 15 C -5.4303 -4.2529 0.0 0
M  V30 16 C -6.7278 -2.0063 0.0 0
M  V30 17 C 3.6642 -1.9823 0.0 0
M  V30 18 F -4.1928 -5.0098 0.0 0
M  V30 19 C -6.7638 -4.9737 0.0 0
M  V30 20 C -8.0613 -2.7271 0.0 0
M  V30 21 N 4.9257 -1.2013 0.0 0
M  V30 22 N -7.1122 -6.4034 0.0 0
M  V30 23 C -8.0973 -4.1928 0.0 0
M  V30 24 C -8.638 -6.5235 0.0 0
M  V30 25 C -9.2387 -5.1539 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000110A1-20220106-C00002

>  <Row No>
50

$$$$
US20220000110A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3695 -0.6607 0.0 0
M  V30 3 C -2.7031 0.1201 0.0 0
M  V30 4 C -1.4056 -2.1264 0.0 0
M  V30 5 N -2.7151 1.6579 0.0 0
M  V30 6 C -4.0366 -0.5886 0.0 0
M  V30 7 N -2.7391 -2.8473 0.0 0
M  V30 8 C -0.1201 -2.8232 0.0 0
M  V30 9 F -5.3942 0.1561 0.0 0
M  V30 10 C -4.0727 -2.0543 0.0 0
M  V30 11 O -0.1201 -4.2889 0.0 0
M  V30 12 O 1.1413 -2.0423 0.0 0
M  V30 13 C -5.3942 -2.7872 0.0 0
M  V30 14 C 2.4027 -2.7632 0.0 0
M  V30 15 C -5.4303 -4.2529 0.0 0
M  V30 16 C -6.7278 -2.0063 0.0 0
M  V30 17 C 3.6642 -1.9823 0.0 0
M  V30 18 F -4.1928 -5.0098 0.0 0
M  V30 19 C -6.7638 -4.9737 0.0 0
M  V30 20 C -8.0613 -2.7271 0.0 0
M  V30 21 C 4.9257 -1.2013 0.0 0
M  V30 22 N -7.1122 -6.4034 0.0 0
M  V30 23 C -8.0973 -4.1928 0.0 0
M  V30 24 C -8.638 -6.5235 0.0 0
M  V30 25 C -9.2387 -5.1539 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000110A1-20220106-C00003

>  <Row No>
51

$$$$
US20220000110A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 N 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000110A1-20220106-C00005

>  <Row No>
52

$$$$
US20220000110A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 C 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000110A1-20220106-C00006

>  <Row No>
53

$$$$
US20220000110A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0365 -1.487 0.0 0
M  V30 3 C 1.2432 -2.2183 0.0 0
M  V30 4 C -1.3894 -2.2183 0.0 0
M  V30 5 C 1.2066 -3.7053 0.0 0
M  V30 6 C 2.523 -1.426 0.0 0
M  V30 7 C -1.426 -3.7053 0.0 0
M  V30 8 Cl 2.4864 -4.4366 0.0 0
M  V30 9 C -0.1462 -4.4366 0.0 0
M  V30 10 S 2.4864 0.134 0.0 0
M  V30 11 N 3.8028 -2.1573 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 5 9
M  V30 9 2 6 10
M  V30 10 1 6 11
M  V30 11 1 7 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000110A1-20220106-C00007

>  <Row No>
54

$$$$
US20220000110A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3171 -0.7119 0.0 0
M  V30 3 C -2.6343 0.0474 0.0 0
M  V30 4 C -1.3527 -2.1597 0.0 0
M  V30 5 C -2.6699 1.5663 0.0 0
M  V30 6 C -3.9515 -0.6645 0.0 0
M  V30 7 C -2.6699 -2.8835 0.0 0
M  V30 8 N -2.7055 3.0853 0.0 0
M  V30 9 Cl -5.2687 0.0949 0.0 0
M  V30 10 C -3.9871 -2.1122 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 3 5 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 1 7 10
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000110A1-20220106-C00008

>  <Row No>
55

$$$$
US20220000110A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.8453 -1.1835 0.0 0
M  V30 3 C 0.1811 -2.524 0.0 0
M  V30 4 C 2.3066 -0.9902 0.0 0
M  V30 5 C 1.0265 -3.7075 0.0 0
M  V30 6 C -1.3525 -2.6447 0.0 0
M  V30 7 C 3.152 -2.1737 0.0 0
M  V30 8 C 2.4877 -3.5143 0.0 0
M  V30 9 O -2.2704 -1.3888 0.0 0
M  V30 10 N 3.3331 -4.6978 0.0 0
M  V30 11 C -3.8041 -1.5095 0.0 0
M  V30 12 N 4.8065 -4.6615 0.0 0
M  V30 13 C 2.8259 -6.0987 0.0 0
M  V30 14 C -4.7582 -0.2898 0.0 0
M  V30 15 C 5.2412 -6.0624 0.0 0
M  V30 16 N 4.0094 -6.944 0.0 0
M  V30 17 C 1.3525 -6.5334 0.0 0
M  V30 18 F -4.7944 1.2559 0.0 0
M  V30 19 F -3.4901 0.483 0.0 0
M  V30 20 C -6.2919 -0.4589 0.0 0
M  V30 21 C 6.6421 -6.4972 0.0 0
M  V30 22 C 0.2053 -5.4948 0.0 0
M  V30 23 C 1.0023 -7.9705 0.0 0
M  V30 24 O 7.7169 -5.4586 0.0 0
M  V30 25 N 6.9199 -7.9343 0.0 0
M  V30 26 C -1.268 -5.9296 0.0 0
M  V30 27 C -0.4709 -8.4053 0.0 0
M  V30 28 C -1.6182 -7.3667 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 2 13 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 1 14 19
M  V30 19 1 14 20
M  V30 20 1 15 21
M  V30 21 2 17 22
M  V30 22 1 17 23
M  V30 23 2 21 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 2 23 27
M  V30 27 2 26 28
M  V30 28 1 7 8
M  V30 29 1 15 16
M  V30 30 1 27 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000110A1-20220106-C00009

>  <Row No>
56

$$$$
US20220000110A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 44 48 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 0.9777 -1.0793 0.0 0 CFG=2
M  V30 3 C 0.4698 -2.4761 0.0 0
M  V30 4 C 2.4126 -0.7238 0.0 0
M  V30 5 N -1.0412 -2.7555 0.0 0
M  V30 6 N 1.4476 -3.5555 0.0 0
M  V30 7 C -1.5491 -4.1523 0.0 0
M  V30 8 C 0.9396 -4.9523 0.0 0
M  V30 9 N -0.5714 -5.2316 0.0 0
M  V30 10 N -3.0602 -4.4317 0.0 0
M  V30 11 N 1.9174 -6.0316 0.0 0
M  V30 12 C -3.5682 -5.8285 0.0 0 CFG=2
M  V30 13 C -5.0412 -6.2602 0.0 0
M  V30 14 C -2.7174 -7.0094 0.0 0 CFG=1
M  V30 15 C -5.0793 -7.7332 0.0 0
M  V30 16 C -6.3872 -5.4729 0.0 0
M  V30 17 C -3.6444 -8.1903 0.0 0
M  V30 18 C -1.2444 -6.9713 0.0 0
M  V30 19 C -6.4253 -8.4443 0.0 0
M  V30 20 C -7.7332 -6.184 0.0 0
M  V30 21 C -7.7713 -7.657 0.0 0
M  V30 22 C -9.0792 -5.3967 0.0 0
M  V30 23 F -0.1015 -12.7998 0.0 0
M  V30 24 C 0.8761 -13.8792 0.0 0 CFG=1
M  V30 25 C 0.3682 -15.276 0.0 0
M  V30 26 C 2.311 -13.5236 0.0 0
M  V30 27 N -1.1428 -15.5553 0.0 0
M  V30 28 N 1.346 -16.3553 0.0 0
M  V30 29 C -1.6507 -16.9522 0.0 0
M  V30 30 C 0.838 -17.7521 0.0 0
M  V30 31 N -0.673 -18.0315 0.0 0
M  V30 32 N -3.1618 -17.2315 0.0 0
M  V30 33 N 1.8158 -18.8315 0.0 0
M  V30 34 C -3.6698 -18.6283 0.0 0 CFG=2
M  V30 35 C -5.1428 -19.0601 0.0 0
M  V30 36 C -2.819 -19.8093 0.0 0 CFG=1
M  V30 37 C -5.1808 -20.5331 0.0 0
M  V30 38 C -6.4888 -18.2728 0.0 0
M  V30 39 C -3.7459 -20.9902 0.0 0
M  V30 40 C -1.346 -19.7712 0.0 0
M  V30 41 C -6.5269 -21.2442 0.0 0
M  V30 42 C -7.8348 -18.9839 0.0 0
M  V30 43 C -7.8729 -20.4569 0.0 0
M  V30 44 C -9.1808 -18.1966 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=1
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 2 7 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 12 10 CFG=1
M  V30 12 1 12 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 14 18 CFG=3
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 2 19 21
M  V30 21 1 20 22
M  V30 22 1 24 23 CFG=3
M  V30 23 1 24 25
M  V30 24 1 24 26
M  V30 25 2 25 27
M  V30 26 1 25 28
M  V30 27 1 27 29
M  V30 28 2 28 30
M  V30 29 2 29 31
M  V30 30 1 29 32
M  V30 31 1 30 33
M  V30 32 1 34 32 CFG=1
M  V30 33 1 34 35
M  V30 34 1 34 36
M  V30 35 2 35 37
M  V30 36 1 35 38
M  V30 37 1 36 39
M  V30 38 1 36 40 CFG=3
M  V30 39 1 37 41
M  V30 40 2 38 42
M  V30 41 2 41 43
M  V30 42 1 42 44
M  V30 43 1 8 9
M  V30 44 1 15 17
M  V30 45 1 20 21
M  V30 46 1 30 31
M  V30 47 1 37 39
M  V30 48 1 42 43
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(6 2 12 14 24 34 36)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000110A1-20220106-C00010

>  <Row No>
57

$$$$
US20220000110A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4653 0.0 0
M  V30 3 N 1.2251 -2.186 0.0 0
M  V30 4 C -1.3693 -2.186 0.0 0
M  V30 5 C 2.4863 -1.4053 0.0 0
M  V30 6 C -2.7025 -1.4053 0.0 0
M  V30 7 C -1.4053 -3.6514 0.0 0
M  V30 8 O 3.8196 -1.9938 0.0 0
M  V30 9 C 2.6064 0.1201 0.0 0
M  V30 10 O -2.7386 0.1321 0.0 0
M  V30 11 C -4.0358 -2.126 0.0 0
M  V30 12 O -0.1441 -4.3841 0.0 0
M  V30 13 C -2.7386 -4.3841 0.0 0
M  V30 14 N 4.7805 -0.8528 0.0 0
M  V30 15 C 4.0358 0.4684 0.0 0
M  V30 16 C -4.0718 0.9248 0.0 0
M  V30 17 C -4.0718 -3.5914 0.0 0
M  V30 18 C -0.1801 -5.8495 0.0 0
M  V30 19 C 4.6244 1.8737 0.0 0
M  V30 20 C 6.0777 2.0659 0.0 0
M  V30 21 C 3.7115 3.1229 0.0 0
M  V30 22 C 5.2129 3.2791 0.0 0
M  V30 23 C 6.9185 0.8888 0.0 0
M  V30 24 C 2.186 3.0028 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 2 5 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 2 7 13
M  V30 13 1 8 14
M  V30 14 1 9 15
M  V30 15 1 10 16
M  V30 16 2 11 17
M  V30 17 1 12 18
M  V30 18 1 15 19
M  V30 19 1 19 20
M  V30 20 1 19 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 13 17
M  V30 25 2 14 15
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000110A1-20220106-C00011

>  <Row No>
58

$$$$
US20220000110A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 1.277 0.7784 0.0 0
M  V30 3 C 2.5541 1.5568 0.0 0
M  V30 4 C -0.0729 1.5568 0.0 0
M  V30 5 C 1.2405 -0.7054 0.0 0
M  V30 6 N 3.8312 0.827 0.0 0
M  V30 7 N 2.5176 3.1136 0.0 0
M  V30 8 C 5.1082 1.6176 0.0 0
M  V30 9 C 3.7947 3.9041 0.0 0
M  V30 10 N 5.0717 3.1744 0.0 0
M  V30 11 N 6.3853 0.8878 0.0 0
M  V30 12 N 3.7582 5.4609 0.0 0
M  V30 13 C 7.6624 1.6662 0.0 0 CFG=2
M  V30 14 C 8.9394 0.9365 0.0 0
M  V30 15 C 7.6259 3.223 0.0 0
M  V30 16 O 10.2165 1.727 0.0 0
M  V30 17 C 11.4936 0.9973 0.0 0
M  V30 18 C 12.7706 1.7757 0.0 0
M  V30 19 C 11.4571 -0.4865 0.0 0
M  V30 20 C 14.0477 1.0459 0.0 0
M  V30 21 C 12.7342 -1.2162 0.0 0
M  V30 22 C 14.0112 -0.4378 0.0 0
M  V30 23 C 15.3248 1.8243 0.0 0
M  V30 24 C 12.6977 -2.7 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 3 6
M  V30 6 1 3 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 1 11 13
M  V30 13 1 13 14
M  V30 14 1 13 15 CFG=1
M  V30 15 1 14 16
M  V30 16 1 16 17
M  V30 17 2 17 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 2 19 21
M  V30 21 2 20 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 9 10
M  V30 25 1 21 22
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 13)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000110A1-20220106-C00012

>  <Row No>
59

$$$$
US20220000110A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 C 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00049001.cdx

>  <name>
US20220000110A1-20220106-C00014

>  <Row No>
60

$$$$
US20220000110A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 C 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00050001.cdx

>  <name>
US20220000110A1-20220106-C00015

>  <Row No>
61

$$$$
US20220000110A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 C 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00052001.cdx

>  <name>
US20220000110A1-20220106-C00017

>  <Row No>
62

$$$$
US20220000110A1-20220106-C00018
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3334 -0.7328 0.0 0
M  V30 3 C -2.6669 0.036 0.0 0
M  V30 4 C -1.3695 -2.1984 0.0 0
M  V30 5 N -2.703 1.5737 0.0 0
M  V30 6 C -4.0004 -0.6967 0.0 0
M  V30 7 N -2.703 -2.9192 0.0 0
M  V30 8 C -0.1081 -2.9192 0.0 0
M  V30 9 F -5.3339 0.072 0.0 0
M  V30 10 C -4.0365 -2.1624 0.0 0
M  V30 11 O -0.1441 -4.3849 0.0 0
M  V30 12 O 1.1532 -2.1384 0.0 0
M  V30 13 C -5.37 -2.8832 0.0 0
M  V30 14 C 2.4147 -2.8592 0.0 0
M  V30 15 C -5.406 -4.3488 0.0 0
M  V30 16 C -6.7035 -2.1023 0.0 0
M  V30 17 C 3.6761 -2.0783 0.0 0
M  V30 18 F -4.1446 -5.0817 0.0 0
M  V30 19 C -6.7395 -5.0817 0.0 0
M  V30 20 C -8.037 -2.8231 0.0 0
M  V30 21 C 4.9375 -1.2974 0.0 0
M  V30 22 N -7.0879 -6.5113 0.0 0
M  V30 23 C -8.073 -4.3008 0.0 0
M  V30 24 C -8.6136 -6.6314 0.0 0
M  V30 25 C -9.2143 -5.2619 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 3 17 21
M  V30 21 1 19 22
M  V30 22 2 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 1 20 23
M  V30 27 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00053001.cdx

>  <name>
US20220000110A1-20220106-C00018

>  <Row No>
63

$$$$
US20220000112A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 33 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C 1.0302 1.103 0.0 0
M  V30 3 C 0.5939 2.606 0.0 0
M  V30 4 C 2.4605 0.7393 0.0 0
M  V30 5 C 1.6242 3.709 0.0 0
M  V30 6 C 3.4908 1.8424 0.0 0
M  V30 7 C 3.0545 3.3454 0.0 0
M  V30 8 C 4.3272 4.1333 0.0 0
M  V30 9 N 5.6726 3.5393 0.0 0
M  V30 10 C 4.4484 5.6726 0.0 0
M  V30 11 C 6.6423 4.6908 0.0 0
M  V30 12 C 5.9514 2.0969 0.0 0
M  V30 13 N 5.8908 6.0242 0.0 0
M  V30 14 C 8.1211 4.7272 0.0 0
M  V30 15 C 8.8605 3.4545 0.0 0
M  V30 16 C 8.8605 6.0726 0.0 0
M  V30 17 O 8.0848 2.1818 0.0 0
M  V30 18 C 10.3393 3.4908 0.0 0
M  V30 19 C 10.3393 6.109 0.0 0
M  V30 20 C 8.8241 0.909 0.0 0
M  V30 21 N 11.0666 2.2181 0.0 0 CHG=1
M  V30 22 C 11.0666 4.8363 0.0 0
M  V30 23 C 8.0363 -0.3636 0.0 0
M  V30 24 O 10.2787 0.9454 0.0 0
M  V30 25 O 12.5453 2.2545 0.0 0 CHG=-1
M  V30 26 C 6.4848 -0.3272 0.0 0
M  V30 27 C 8.7757 -1.6363 0.0 0
M  V30 28 C 5.6969 -1.5999 0.0 0
M  V30 29 C 7.9878 -2.909 0.0 0
M  V30 30 C 6.4242 -2.8727 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 2 8 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 2 18 22
M  V30 22 1 20 23
M  V30 23 2 21 24
M  V30 24 1 21 25
M  V30 25 2 23 26
M  V30 26 1 23 27
M  V30 27 1 26 28
M  V30 28 2 27 29
M  V30 29 2 28 30
M  V30 30 1 6 7
M  V30 31 2 11 13
M  V30 32 1 19 22
M  V30 33 1 29 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000112A1-20220106-C00002

>  <Row No>
64

$$$$
US20220000112A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0348 -1.4651 0.0 0
M  V30 3 C -1.372 -2.1744 0.0 0
M  V30 4 C 1.2325 -2.1744 0.0 0
M  V30 5 C -2.7093 -1.372 0.0 0
M  V30 6 C -1.4069 -3.6395 0.0 0
M  V30 7 N 2.5 -1.372 0.0 0
M  V30 8 C -4.0465 -2.0813 0.0 0
M  V30 9 C -2.7441 -4.3372 0.0 0
M  V30 10 O 3.7674 -0.5813 0.0 0
M  V30 11 C -4.0814 -3.5465 0.0 0
M  V30 12 C -5.4186 -4.2441 0.0 0
M  V30 13 O -9.8604 10.6046 0.0 0
M  V30 14 C -9.8953 9.1395 0.0 0
M  V30 15 C -11.2325 8.4418 0.0 0
M  V30 16 C -8.6279 8.4418 0.0 0
M  V30 17 C -12.5697 9.2325 0.0 0
M  V30 18 C -11.2674 6.9767 0.0 0
M  V30 19 C -13.9069 8.5348 0.0 0
M  V30 20 C -12.6046 6.2674 0.0 0
M  V30 21 C -13.9418 7.0697 0.0 0
M  V30 22 C -15.279 6.3604 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7 CFG=2
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 11 12
M  V30 12 2 13 14
M  V30 13 1 14 15
M  V30 14 1 14 16
M  V30 15 2 15 17
M  V30 16 1 15 18
M  V30 17 1 17 19
M  V30 18 2 18 20
M  V30 19 2 19 21
M  V30 20 1 21 22
M  V30 21 1 9 11
M  V30 22 1 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000112A1-20220106-C00009

>  <Row No>
65

$$$$
US20220000112A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 39 39 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0571 -1.4466 0.0 0
M  V30 3 C -1.4276 -2.1318 0.0 0
M  V30 4 C 1.1991 -2.1318 0.0 0
M  V30 5 C -2.7981 -1.3324 0.0 0
M  V30 6 C -1.4847 -3.5785 0.0 0
M  V30 7 N 2.4554 -1.3324 0.0 0
M  V30 8 C -4.1686 -2.0176 0.0 0
M  V30 9 C -2.8552 -4.2637 0.0 0
M  V30 10 O 3.7117 -0.5329 0.0 0
M  V30 11 C -4.2257 -3.4643 0.0 0
M  V30 12 C -5.5962 -4.1495 0.0 0
M  V30 13 O -4.8729 2.2841 0.0 0
M  V30 14 C -4.93 0.8375 0.0 0
M  V30 15 O -3.6737 0.1522 0.0 0
M  V30 16 C -6.3005 0.1522 0.0 0
M  V30 17 O 12.9436 -19.187 0.0 0 CHG=-1
M  V30 18 N 11.9919 -20.6717 0.0 0 CHG=1
M  V30 19 C 12.7913 -21.7948 0.0 0
M  V30 20 C 10.5072 -21.0715 0.0 0
M  V30 21 N 11.8777 -22.9178 0.0 0
M  V30 22 C 10.45 -22.5181 0.0 0
M  V30 23 C 12.5629 -24.1741 0.0 0
M  V30 24 C 9.0795 -23.2034 0.0 0
M  V30 25 C 7.709 -22.4039 0.0 0
M  V30 26 C 9.0224 -24.65 0.0 0
M  V30 27 C 6.3385 -23.0891 0.0 0
M  V30 28 C 7.6519 -25.3353 0.0 0
M  V30 29 C 6.2814 -24.5358 0.0 0
M  V30 30 C 4.9109 -25.221 0.0 0
M  V30 31 N 1.9796 -12.0299 0.0 0
M  V30 32 C 3.2359 -12.7152 0.0 0
M  V30 33 C 0.6091 -12.7152 0.0 0
M  V30 34 C 1.9225 -10.4691 0.0 0
M  V30 35 N 3.1788 -14.1618 0.0 0
M  V30 36 N 0.552 -14.1618 0.0 0
M  V30 37 C 1.8083 -14.8471 0.0 0
M  V30 38 C 4.4351 -14.8471 0.0 0
M  V30 39 C -0.8184 -14.8471 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7 CFG=2
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 11 12
M  V30 12 2 13 14
M  V30 13 1 14 15
M  V30 14 1 14 16
M  V30 15 1 17 18
M  V30 16 2 18 19
M  V30 17 1 18 20
M  V30 18 1 19 21
M  V30 19 2 20 22
M  V30 20 1 21 23
M  V30 21 1 22 24
M  V30 22 2 24 25
M  V30 23 1 24 26
M  V30 24 1 25 27
M  V30 25 2 26 28
M  V30 26 2 27 29
M  V30 27 1 29 30
M  V30 28 1 31 32
M  V30 29 1 31 33
M  V30 30 1 31 34
M  V30 31 1 32 35
M  V30 32 1 33 36
M  V30 33 1 35 37
M  V30 34 1 35 38
M  V30 35 1 36 39
M  V30 36 1 9 11
M  V30 37 1 21 22
M  V30 38 1 28 29
M  V30 39 1 36 37
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000112A1-20220106-C00010

>  <Row No>
66

$$$$
US20220000112A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 51 54 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C 1.224 0.8043 0.0 0
M  V30 3 C 2.4481 0.1049 0.0 0
M  V30 4 C 1.1716 2.3257 0.0 0
M  V30 5 F 2.3957 -1.3115 0.0 0
M  V30 6 C 3.6722 0.9093 0.0 0
M  V30 7 C 2.3957 3.1301 0.0 0
M  V30 8 C 3.6197 2.4306 0.0 0
M  V30 9 C 4.8438 3.235 0.0 0
M  V30 10 F 5.5433 2.0109 0.0 0
M  V30 11 F 6.0679 4.0394 0.0 0
M  V30 12 F 4.0394 4.564 0.0 0
M  V30 13 F 9.9325 -10.632 0.0 0
M  V30 14 C 10.9468 -9.5128 0.0 0
M  V30 15 C 10.5096 -8.0439 0.0 0
M  V30 16 C 12.3107 -9.8451 0.0 0
M  V30 17 C 8.2713 -7.257 0.0 0
M  V30 18 C 11.5238 -6.9248 0.0 0
M  V30 19 C 13.325 -8.7259 0.0 0
M  V30 20 N 7.327 -6.0154 0.0 0 CHG=1
M  V30 21 N 7.327 -8.3937 0.0 0
M  V30 22 C 12.8878 -7.257 0.0 0
M  V30 23 C 14.689 -9.0582 0.0 0
M  V30 24 O 8.1663 -4.5291 0.0 0 CHG=-1
M  V30 25 C 5.8756 -6.4351 0.0 0
M  V30 26 C 5.8756 -7.8691 0.0 0
M  V30 27 C 8.0264 -9.6178 0.0 0
M  V30 28 F 14.2518 -10.4222 0.0 0
M  V30 29 F 16.0529 -9.3904 0.0 0
M  V30 30 F 15.0212 -7.5893 0.0 0
M  V30 31 C 4.5465 -8.5685 0.0 0
M  V30 32 C 3.2175 -7.7641 0.0 0
M  V30 33 C 4.4941 -9.985 0.0 0
M  V30 34 C 1.8885 -8.4636 0.0 0
M  V30 35 C 3.1651 -10.6845 0.0 0
M  V30 36 C 1.8361 -9.8801 0.0 0
M  V30 37 C 0.5071 -10.5795 0.0 0
M  V30 38 O 4.1968 17.7667 0.0 0 CHG=-1
M  V30 39 N 3.2525 16.3852 0.0 0 CHG=1
M  V30 40 C 4.0919 15.2485 0.0 0
M  V30 41 C 1.8011 15.9655 0.0 0
M  V30 42 N 3.1476 14.1119 0.0 0
M  V30 43 C 1.7486 14.5491 0.0 0
M  V30 44 C 3.8471 12.8878 0.0 0
M  V30 45 C 0.4196 13.8496 0.0 0
M  V30 46 C -0.9093 14.654 0.0 0
M  V30 47 C 0.3672 12.4331 0.0 0
M  V30 48 C -2.2383 13.9545 0.0 0
M  V30 49 C -0.9617 11.7337 0.0 0
M  V30 50 C -2.2907 12.5381 0.0 0
M  V30 51 C -3.6197 11.8386 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 13 14
M  V30 13 2 14 15
M  V30 14 1 14 16
M  V30 15 1 15 17
M  V30 16 1 15 18
M  V30 17 2 16 19
M  V30 18 2 17 20
M  V30 19 1 17 21
M  V30 20 2 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 20 25
M  V30 24 1 21 26
M  V30 25 1 21 27
M  V30 26 1 23 28
M  V30 27 1 23 29
M  V30 28 1 23 30
M  V30 29 1 26 31
M  V30 30 2 31 32
M  V30 31 1 31 33
M  V30 32 1 32 34
M  V30 33 2 33 35
M  V30 34 2 34 36
M  V30 35 1 36 37
M  V30 36 1 38 39
M  V30 37 2 39 40
M  V30 38 1 39 41
M  V30 39 1 40 42
M  V30 40 2 41 43
M  V30 41 1 42 44
M  V30 42 1 43 45
M  V30 43 2 45 46
M  V30 44 1 45 47
M  V30 45 1 46 48
M  V30 46 2 47 49
M  V30 47 2 48 50
M  V30 48 1 50 51
M  V30 49 1 7 8
M  V30 50 1 19 22
M  V30 51 2 25 26
M  V30 52 1 35 36
M  V30 53 1 42 43
M  V30 54 1 49 50
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000112A1-20220106-C00011

>  <Row No>
67

$$$$
US20220000112A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 50 53 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Fe 0.0 0.0 0.0 0 VAL=-1
M  V30 2 F -7.7156 -1.3615 0.0 0
M  V30 3 C -6.7228 -0.2836 0.0 0
M  V30 4 C -7.1483 1.1772 0.0 0
M  V30 5 C -5.347 -0.624 0.0 0
M  V30 6 C -8.9638 1.6027 0.0 0
M  V30 7 C -6.1555 2.2551 0.0 0
M  V30 8 C -4.3542 0.4538 0.0 0
M  V30 9 N -9.758 2.9217 0.0 0 CHG=1
M  V30 10 N -9.985 0.5531 0.0 0
M  V30 11 C -4.7797 1.9147 0.0 0
M  V30 12 C -2.9784 0.1134 0.0 0
M  V30 13 O -8.7226 4.5811 0.0 0 CHG=-1
M  V30 14 C -11.2473 2.6522 0.0 0
M  V30 15 C -11.3749 1.2055 0.0 0
M  V30 16 C -9.6446 -0.8226 0.0 0
M  V30 17 F -3.4039 -1.2623 0.0 0
M  V30 18 F -1.6027 -0.2269 0.0 0
M  V30 19 F -2.638 1.5743 0.0 0
M  V30 20 C -12.694 0.4964 0.0 0
M  V30 21 C -14.013 1.2906 0.0 0
M  V30 22 C -12.7365 -0.936 0.0 0
M  V30 23 C -15.332 0.5815 0.0 0
M  V30 24 C -14.0556 -1.6452 0.0 0
M  V30 25 C -15.3746 -0.8509 0.0 0
M  V30 26 C -16.6936 -1.5601 0.0 0
M  V30 27 F -3.177 -7.8291 0.0 0
M  V30 28 C -2.1842 -6.7512 0.0 0
M  V30 29 C -2.6097 -5.2903 0.0 0
M  V30 30 C -0.8084 -7.0916 0.0 0
M  V30 31 C -4.4251 -4.8648 0.0 0
M  V30 32 C -1.6168 -4.2124 0.0 0
M  V30 33 C 0.1843 -6.0136 0.0 0
M  V30 34 N -5.2194 -3.5458 0.0 0
M  V30 35 N -5.4463 -5.9144 0.0 0
M  V30 36 C -0.2411 -4.5528 0.0 0
M  V30 37 C 1.5601 -6.354 0.0 0
M  V30 38 C -6.7086 -3.8152 0.0 0
M  V30 39 C -6.8363 -5.2619 0.0 0
M  V30 40 C -5.1059 -7.2901 0.0 0
M  V30 41 F 1.1346 -7.7298 0.0 0
M  V30 42 F 2.9359 -6.6944 0.0 0
M  V30 43 F 1.9005 -4.8932 0.0 0
M  V30 44 C -8.1553 -5.9711 0.0 0
M  V30 45 C -9.4744 -5.1768 0.0 0
M  V30 46 C -8.1979 -7.4036 0.0 0
M  V30 47 C -10.7934 -5.886 0.0 0
M  V30 48 C -9.5169 -8.1128 0.0 0
M  V30 49 C -10.836 -7.3185 0.0 0
M  V30 50 C -12.155 -8.0277 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 3
M  V30 2 2 3 4
M  V30 3 1 3 5
M  V30 4 1 4 6
M  V30 5 1 4 7
M  V30 6 2 5 8
M  V30 7 2 6 9
M  V30 8 1 6 10
M  V30 9 2 7 11
M  V30 10 1 8 12
M  V30 11 1 9 13
M  V30 12 1 9 14
M  V30 13 1 10 15
M  V30 14 1 10 16
M  V30 15 1 12 17
M  V30 16 1 12 18
M  V30 17 1 12 19
M  V30 18 1 15 20
M  V30 19 2 20 21
M  V30 20 1 20 22
M  V30 21 1 21 23
M  V30 22 2 22 24
M  V30 23 2 23 25
M  V30 24 1 25 26
M  V30 25 1 27 28
M  V30 26 2 28 29
M  V30 27 1 28 30
M  V30 28 1 29 31
M  V30 29 1 29 32
M  V30 30 2 30 33
M  V30 31 2 31 34
M  V30 32 1 31 35
M  V30 33 2 32 36
M  V30 34 1 33 37
M  V30 35 1 34 38
M  V30 36 1 35 39
M  V30 37 1 35 40
M  V30 38 1 37 41
M  V30 39 1 37 42
M  V30 40 1 37 43
M  V30 41 1 39 44
M  V30 42 2 44 45
M  V30 43 1 44 46
M  V30 44 1 45 47
M  V30 45 2 46 48
M  V30 46 2 47 49
M  V30 47 1 49 50
M  V30 48 1 8 11
M  V30 49 2 14 15
M  V30 50 1 24 25
M  V30 51 1 33 36
M  V30 52 2 38 39
M  V30 53 1 48 49
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000112A1-20220106-C00012

>  <Row No>
68

$$$$
US20220000112A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 54 56 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 C 1.001 1.0868 0.0 0
M  V30 3 C 0.4004 -1.3729 0.0 0
M  V30 4 C 0.572 2.5599 0.0 0
M  V30 5 C 2.3882 0.7436 0.0 0
M  V30 6 C -0.6435 -2.4025 0.0 0
M  V30 7 C -1.2585 2.9889 0.0 0
M  V30 8 C 1.5731 3.6468 0.0 0
M  V30 9 C 3.3893 1.8305 0.0 0
M  V30 10 N -2.0593 4.3189 0.0 0
M  V30 11 N -2.2881 1.9306 0.0 0
M  V30 12 C 2.9603 3.3035 0.0 0
M  V30 13 C 4.7765 1.4873 0.0 0
M  V30 14 C -3.5609 4.0472 0.0 0
M  V30 15 C -3.6897 2.5885 0.0 0
M  V30 16 C -1.9449 0.5434 0.0 0
M  V30 17 F 4.3475 0.1001 0.0 0
M  V30 18 F 6.1638 1.144 0.0 0
M  V30 19 F 5.1198 2.9603 0.0 0
M  V30 20 C -5.0197 1.8734 0.0 0
M  V30 21 C -6.3497 2.6743 0.0 0
M  V30 22 C -5.0626 0.429 0.0 0
M  V30 23 C -7.6797 1.9592 0.0 0
M  V30 24 C -6.3926 -0.286 0.0 0
M  V30 25 C -7.7226 0.5148 0.0 0
M  V30 26 C -9.0526 -0.2002 0.0 0
M  V30 27 S 13.9579 -9.2671 0.0 0 CHG=-1
M  V30 28 C 15.2021 -8.4663 0.0 0
M  V30 29 C 16.4463 -9.1813 0.0 0
M  V30 30 Na 12.585 -8.4663 0.0 0 CHG=1
M  V30 31 F -5.1484 7.0933 0.0 0
M  V30 32 C -4.1473 8.1802 0.0 0
M  V30 33 C -4.5763 9.6532 0.0 0
M  V30 34 C -2.7601 7.837 0.0 0
M  V30 35 C -6.4069 10.0823 0.0 0
M  V30 36 C -3.5752 10.7401 0.0 0
M  V30 37 C -1.759 8.9239 0.0 0
M  V30 38 N -7.2077 11.4123 0.0 0
M  V30 39 N -7.4366 9.024 0.0 0
M  V30 40 C -2.188 10.3969 0.0 0
M  V30 41 C -0.3718 8.5807 0.0 0
M  V30 42 C -8.7094 11.1406 0.0 0
M  V30 43 C -8.8381 9.6819 0.0 0
M  V30 44 C -7.0933 7.6368 0.0 0
M  V30 45 F -0.8008 7.1934 0.0 0
M  V30 46 F 1.0153 8.2374 0.0 0
M  V30 47 F -0.0286 10.0537 0.0 0
M  V30 48 C -10.1681 8.9668 0.0 0
M  V30 49 C -11.4981 9.7677 0.0 0
M  V30 50 C -10.211 7.5224 0.0 0
M  V30 51 C -12.8281 9.0526 0.0 0
M  V30 52 C -11.541 6.8073 0.0 0
M  V30 53 C -12.871 7.6082 0.0 0
M  V30 54 C -14.201 6.8931 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 4 8
M  V30 8 2 5 9
M  V30 9 2 7 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 11 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 1 13 19
M  V30 19 1 15 20
M  V30 20 2 20 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 2 22 24
M  V30 24 2 23 25
M  V30 25 1 25 26
M  V30 26 1 27 28
M  V30 27 1 28 29
M  V30 28 1 31 32
M  V30 29 2 32 33
M  V30 30 1 32 34
M  V30 31 1 33 35
M  V30 32 1 33 36
M  V30 33 2 34 37
M  V30 34 2 35 38
M  V30 35 1 35 39
M  V30 36 2 36 40
M  V30 37 1 37 41
M  V30 38 1 38 42
M  V30 39 1 39 43
M  V30 40 1 39 44
M  V30 41 1 41 45
M  V30 42 1 41 46
M  V30 43 1 41 47
M  V30 44 1 43 48
M  V30 45 2 48 49
M  V30 46 1 48 50
M  V30 47 1 49 51
M  V30 48 2 50 52
M  V30 49 2 51 53
M  V30 50 1 53 54
M  V30 51 1 9 12
M  V30 52 2 14 15
M  V30 53 1 24 25
M  V30 54 1 37 40
M  V30 55 2 42 43
M  V30 56 1 52 53
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000112A1-20220106-C00013

>  <Row No>
69

$$$$
US20220000112A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 54 58 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -1.086 1.086 0.0 0
M  V30 3 O 1.0002 -1.0002 0.0 0
M  V30 4 C 1.0002 1.086 0.0 0
M  V30 5 C -1.086 -1.0002 0.0 0
M  V30 6 C 0.5715 2.5578 0.0 0
M  V30 7 C 2.3863 0.743 0.0 0
M  V30 8 C -2.615 -0.9574 0.0 0
M  V30 9 C -1.2574 2.9865 0.0 0
M  V30 10 C 1.5718 3.6438 0.0 0
M  V30 11 C 3.3866 1.829 0.0 0
M  V30 12 N -2.0577 4.3155 0.0 0
M  V30 13 N -2.2863 1.9291 0.0 0
M  V30 14 C 2.9579 3.3009 0.0 0
M  V30 15 C 4.7727 1.4861 0.0 0
M  V30 16 C -3.5581 4.0439 0.0 0
M  V30 17 C -3.6867 2.5864 0.0 0
M  V30 18 C -2.715 0.543 0.0 0
M  V30 19 F 4.344 0.1 0.0 0
M  V30 20 F 6.1588 1.1431 0.0 0
M  V30 21 F 5.1157 2.9579 0.0 0
M  V30 22 C -5.0157 1.8719 0.0 0
M  V30 23 C -6.3446 2.6721 0.0 0
M  V30 24 C -5.0585 0.4286 0.0 0
M  V30 25 C -7.6735 1.9576 0.0 0
M  V30 26 C -6.3875 -0.2857 0.0 0
M  V30 27 C -7.7164 0.5144 0.0 0
M  V30 28 C -9.0454 -0.2 0.0 0
M  V30 29 S -5.1443 8.4595 0.0 0
M  V30 30 C -4.144 9.5455 0.0 0
M  V30 31 C -4.7441 7.0877 0.0 0
M  V30 32 C -4.5727 11.0173 0.0 0
M  V30 33 C -2.7579 9.2025 0.0 0
M  V30 34 C -5.7873 6.0588 0.0 0
M  V30 35 C -6.4018 11.446 0.0 0
M  V30 36 C -3.5724 12.1034 0.0 0
M  V30 37 C -1.7576 10.2886 0.0 0
M  V30 38 N -7.202 12.775 0.0 0
M  V30 39 N -7.4306 10.3886 0.0 0
M  V30 40 C -2.1863 11.7604 0.0 0
M  V30 41 C -0.3715 9.9456 0.0 0
M  V30 42 C -8.7024 12.5035 0.0 0
M  V30 43 C -8.831 11.0459 0.0 0
M  V30 44 C -7.0877 9.0025 0.0 0
M  V30 45 F -0.8002 8.5595 0.0 0
M  V30 46 F 1.0145 9.6027 0.0 0
M  V30 47 F -0.0285 11.4175 0.0 0
M  V30 48 C -10.16 10.3314 0.0 0
M  V30 49 C -11.4889 11.1317 0.0 0
M  V30 50 C -10.2028 8.8882 0.0 0
M  V30 51 C -12.8179 10.4172 0.0 0
M  V30 52 C -11.5318 8.1737 0.0 0
M  V30 53 C -12.8607 8.9739 0.0 0
M  V30 54 C -14.1897 8.2594 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 2 7 11
M  V30 11 2 9 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 1 15 19
M  V30 19 1 15 20
M  V30 20 1 15 21
M  V30 21 1 17 22
M  V30 22 2 22 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 2 24 26
M  V30 26 2 25 27
M  V30 27 1 27 28
M  V30 28 1 29 30
M  V30 29 1 29 31
M  V30 30 2 30 32
M  V30 31 1 30 33
M  V30 32 1 31 34
M  V30 33 1 32 35
M  V30 34 1 32 36
M  V30 35 2 33 37
M  V30 36 2 35 38
M  V30 37 1 35 39
M  V30 38 2 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 39 44
M  V30 43 1 41 45
M  V30 44 1 41 46
M  V30 45 1 41 47
M  V30 46 1 43 48
M  V30 47 2 48 49
M  V30 48 1 48 50
M  V30 49 1 49 51
M  V30 50 2 50 52
M  V30 51 2 51 53
M  V30 52 1 53 54
M  V30 53 1 11 14
M  V30 54 2 16 17
M  V30 55 1 26 27
M  V30 56 1 37 40
M  V30 57 2 42 43
M  V30 58 1 52 53
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000112A1-20220106-C00014

>  <Row No>
70

$$$$
US20220000113A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.7706 1.3365 0.0 0
M  V30 3 O 0.7224 -1.2642 0.0 0
M  V30 4 N -1.3365 -0.7224 0.0 0
M  V30 5 C 1.2642 0.7706 0.0 0
M  V30 6 C -1.3726 -2.1914 0.0 0
M  V30 7 C -2.673 0.0481 0.0 0
M  V30 8 C 2.5285 0.0481 0.0 0
M  V30 9 C 1.2281 2.3118 0.0 0
M  V30 10 O -0.1083 -2.9138 0.0 0
M  V30 11 N -2.7091 -2.9138 0.0 0
M  V30 12 C -4.0096 -0.6742 0.0 0
M  V30 13 C 3.7928 0.8308 0.0 0
M  V30 14 C 2.4924 3.0945 0.0 0
M  V30 15 C -4.0457 -2.1312 0.0 0
M  V30 16 C -2.7453 -4.3828 0.0 0
M  V30 17 F -5.3461 0.0963 0.0 0
M  V30 18 C 3.7567 2.372 0.0 0
M  V30 19 N -5.3822 -2.8536 0.0 0
M  V30 20 C 5.021 3.1547 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 6 11
M  V30 11 2 7 12
M  V30 12 1 8 13
M  V30 13 2 9 14
M  V30 14 1 11 15
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 18 20
M  V30 20 1 12 15
M  V30 21 1 14 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000113A1-20220106-C00001

>  <Row No>
71

$$$$
US20220000113A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.7706 1.3365 0.0 0
M  V30 3 O 0.7224 -1.2642 0.0 0
M  V30 4 N -1.3365 -0.7224 0.0 0
M  V30 5 C 1.2642 0.7706 0.0 0
M  V30 6 C -1.3726 -2.1914 0.0 0
M  V30 7 C -2.673 0.0481 0.0 0
M  V30 8 C 2.5285 0.0481 0.0 0
M  V30 9 C 1.2281 2.3118 0.0 0
M  V30 10 O -0.1083 -2.9138 0.0 0
M  V30 11 N -2.7091 -2.9138 0.0 0
M  V30 12 C -4.0096 -0.6742 0.0 0
M  V30 13 C 3.7928 0.8308 0.0 0
M  V30 14 C 2.4924 3.0945 0.0 0
M  V30 15 C -4.0457 -2.1312 0.0 0
M  V30 16 C -2.7453 -4.3828 0.0 0
M  V30 17 F -5.3461 0.0963 0.0 0
M  V30 18 C 3.7567 2.372 0.0 0
M  V30 19 N -5.3822 -2.8536 0.0 0
M  V30 20 C 5.021 3.1547 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 6 11
M  V30 11 2 7 12
M  V30 12 1 8 13
M  V30 13 2 9 14
M  V30 14 1 11 15
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 18 20
M  V30 20 1 12 15
M  V30 21 1 14 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000113A1-20220106-C00002

>  <Row No>
72

$$$$
US20220000113A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0358 -1.459 0.0 0
M  V30 3 C -1.3633 -2.1885 0.0 0
M  V30 4 C 1.2198 -2.1885 0.0 0
M  V30 5 C -1.3992 -3.6476 0.0 0
M  V30 6 C -2.6908 -1.4112 0.0 0 CFG=1
M  V30 7 C 1.1839 -3.6476 0.0 0
M  V30 8 C -0.1435 -4.3771 0.0 0
M  V30 9 O -3.4562 -0.0837 0.0 0
M  V30 10 C -4.2216 -1.3753 0.0 0 CFG=2
M  V30 11 C -5.3099 -0.287 0.0 0
M  V30 12 C -5.5491 -2.1048 0.0 0
M  V30 13 C -4.9512 1.1959 0.0 0
M  V30 14 C -6.7929 -0.6458 0.0 0
M  V30 15 N -5.585 -3.5639 0.0 0
M  V30 16 C -6.0395 2.2842 0.0 0
M  V30 17 C -7.8812 0.4424 0.0 0
M  V30 18 N -6.8288 -4.401 0.0 0
M  V30 19 C -4.413 -4.401 0.0 0
M  V30 20 C -7.5224 1.9254 0.0 0
M  V30 21 C -6.3982 -5.7883 0.0 0
M  V30 22 N -4.9153 -5.7883 0.0 0
M  V30 23 F -8.6107 3.0137 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 6 3 CFG=3
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 10 11
M  V30 11 1 10 12 CFG=3
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 2 18 21
M  V30 21 2 19 22
M  V30 22 1 20 23
M  V30 23 1 7 8
M  V30 24 1 9 10
M  V30 25 1 17 20
M  V30 26 1 21 22
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 6 10)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000113A1-20220106-C00003

>  <Row No>
73

$$$$
US20220000113A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0352 -1.4801 0.0 0
M  V30 3 C 1.2451 -2.2084 0.0 0
M  V30 4 C -1.3861 -2.2084 0.0 0
M  V30 5 C 1.2099 -3.6885 0.0 0
M  V30 6 C -1.4213 -3.6885 0.0 0
M  V30 7 C -0.1409 -4.4051 0.0 0
M  V30 8 C -0.1762 -5.8852 0.0 0
M  V30 9 O -1.5271 -5.0864 0.0 0
M  V30 10 C 1.1042 -6.6136 0.0 0
M  V30 11 C -1.5271 -6.6136 0.0 0
M  V30 12 C 1.0689 -8.0937 0.0 0
M  V30 13 C 2.3846 -5.8148 0.0 0
M  V30 14 N -1.5623 -8.0937 0.0 0
M  V30 15 C 0.2701 -9.3741 0.0 0
M  V30 16 C 1.7855 -9.3741 0.0 0
M  V30 17 N -2.831 -8.963 0.0 0
M  V30 18 C -0.3641 -8.963 0.0 0
M  V30 19 C -2.4081 -10.3726 0.0 0
M  V30 20 N -0.8575 -10.3726 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 8 10
M  V30 10 1 8 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 1 14 17
M  V30 17 1 14 18
M  V30 18 2 17 19
M  V30 19 2 18 20
M  V30 20 1 6 7
M  V30 21 1 15 16
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000113A1-20220106-C00004

>  <Row No>
74

$$$$
US20220000113A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.2853 -0.7396 0.0 0
M  V30 3 C 1.2489 -2.2311 0.0 0
M  V30 4 C 2.5706 0.0485 0.0 0
M  V30 5 C 2.5342 -2.9586 0.0 0
M  V30 6 C 3.8559 -0.6911 0.0 0
M  V30 7 C 3.8195 -2.1704 0.0 0
M  V30 8 C 5.1049 -2.898 0.0 0
M  V30 9 C 6.3902 -2.1098 0.0 0
M  V30 10 C 7.7483 -2.704 0.0 0
M  V30 11 C 6.5114 -0.5577 0.0 0
M  V30 12 O 9.1912 -3.0677 0.0 0
M  V30 13 C 8.7304 -1.5399 0.0 0
M  V30 14 C 8.0271 -4.1591 0.0 0
M  V30 15 C 7.9665 -0.2061 0.0 0
M  V30 16 C 10.2098 -1.6612 0.0 0
M  V30 17 C 9.4701 -0.1818 0.0 0
M  V30 18 N 9.4458 -4.5956 0.0 0
M  V30 19 N 9.8824 -6.0143 0.0 0
M  V30 20 C 10.6463 -3.6619 0.0 0
M  V30 21 C 11.3738 -5.9779 0.0 0
M  V30 22 C 11.8467 -4.5228 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 13 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 2 19 21
M  V30 21 2 20 22
M  V30 22 1 6 7
M  V30 23 1 13 15
M  V30 24 1 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000113A1-20220106-C00005

>  <Row No>
75

$$$$
US20220000113A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7044 -1.2797 0.0 0
M  V30 3 C -0.0821 -2.5594 0.0 0
M  V30 4 C 2.1837 -1.2445 0.0 0
M  V30 5 C 0.6222 -3.8391 0.0 0
M  V30 6 C 2.8881 -2.5242 0.0 0
M  V30 7 C 2.1015 -3.8039 0.0 0
M  V30 8 C 2.806 -5.0836 0.0 0 CFG=1
M  V30 9 C 4.0857 -4.2853 0.0 0
M  V30 10 C 3.5104 -6.3634 0.0 0
M  V30 11 C 1.4558 -5.7998 0.0 0
M  V30 12 N 5.3654 -3.4869 0.0 0
M  V30 13 N 4.9897 -6.3282 0.0 0
M  V30 14 C 0.1056 -4.9897 0.0 0
M  V30 15 N 5.8585 -5.0602 0.0 0
M  V30 16 C 5.8585 -7.5257 0.0 0
M  V30 17 C -1.2445 -5.7059 0.0 0
M  V30 18 C 7.2674 -5.4828 0.0 0
M  V30 19 C 7.2674 -7.0326 0.0 0
M  V30 20 C -2.5946 -4.8958 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 8 7 CFG=1
M  V30 8 1 8 9
M  V30 9 1 8 10
M  V30 10 1 8 11
M  V30 11 3 9 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 2 16 19
M  V30 19 1 17 20
M  V30 20 1 6 7
M  V30 21 1 18 19
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 8)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000113A1-20220106-C00006

>  <Row No>
76

$$$$
US20220000113A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.375 -0.6576 0.0 0
M  V30 3 C -1.4946 -2.1283 0.0 0
M  V30 4 C -2.6784 0.1913 0.0 0
M  V30 5 C -2.8697 -2.786 0.0 0
M  V30 6 C -0.263 -2.9056 0.0 0
M  V30 7 C -4.0535 -0.4663 0.0 0
M  V30 8 C -4.173 -1.937 0.0 0
M  V30 9 O 1.0761 -3.4915 0.0 0
M  V30 10 O -0.1434 -1.375 0.0 0
M  V30 11 C -1.6022 -3.623 0.0 0
M  V30 12 Cl -5.3568 0.3826 0.0 0
M  V30 13 C 2.0446 -2.3436 0.0 0
M  V30 14 C 1.2913 -1.0283 0.0 0
M  V30 15 N -1.6381 -5.0937 0.0 0
M  V30 16 C 3.5034 -2.4631 0.0 0
M  V30 17 N -2.8936 -5.9427 0.0 0
M  V30 18 C -0.4543 -5.9427 0.0 0
M  V30 19 C 4.3524 -1.2076 0.0 0
M  V30 20 C -2.4631 -7.3417 0.0 0
M  V30 21 N -0.9565 -7.3417 0.0 0
M  V30 22 C 5.8112 -1.3272 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 13 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 2 17 20
M  V30 20 2 18 21
M  V30 21 1 19 22
M  V30 22 1 7 8
M  V30 23 1 13 14
M  V30 24 1 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000113A1-20220106-C00007

>  <Row No>
77

$$$$
US20220000113A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0353 -1.4836 0.0 0
M  V30 3 C 1.2481 -2.1901 0.0 0
M  V30 4 C -1.3894 -2.1901 0.0 0
M  V30 5 C 1.2128 -3.6737 0.0 0
M  V30 6 C 2.5315 -1.4012 0.0 0
M  V30 7 C -1.4247 -3.6737 0.0 0
M  V30 8 C -0.1412 -4.3802 0.0 0
M  V30 9 C 3.815 -2.1076 0.0 0 CFG=1
M  V30 10 O 4.5215 -0.7535 0.0 0
M  V30 11 C 5.0985 -2.8259 0.0 0
M  V30 12 C 2.4609 -2.8259 0.0 0
M  V30 13 Cl 5.4517 -1.3187 0.0 0
M  V30 14 C 6.5821 -2.7906 0.0 0
M  V30 15 C 5.8167 -4.1094 0.0 0
M  V30 16 N 2.4256 -4.3095 0.0 0
M  V30 17 N 1.1539 -5.1809 0.0 0
M  V30 18 C 3.6266 -5.1809 0.0 0
M  V30 19 C 1.5778 -6.5939 0.0 0
M  V30 20 S 5.0396 -4.6863 0.0 0
M  V30 21 N 3.1321 -6.5939 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 9 6 CFG=1
M  V30 9 1 9 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 16 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 7 8
M  V30 22 1 14 15
M  V30 23 1 19 21
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 9)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000113A1-20220106-C00008

>  <Row No>
78

$$$$
US20220000113A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -0.0363 -1.4797 0.0 0
M  V30 3 F -1.3826 -2.2074 0.0 0
M  V30 4 F -1.3826 -0.6792 0.0 0
M  V30 5 C 1.2371 -2.2074 0.0 0
M  V30 6 N 2.5106 -1.4069 0.0 0
M  V30 7 C 1.2007 -3.6871 0.0 0
M  V30 8 C 3.7841 -2.1346 0.0 0
M  V30 9 C 2.4742 -4.4148 0.0 0
M  V30 10 O 5.0576 -1.3341 0.0 0
M  V30 11 C 3.7477 -3.6143 0.0 0
M  V30 12 C 6.3311 -2.0618 0.0 0
M  V30 13 C 7.6047 -1.2613 0.0 0
M  V30 14 C 8.8782 -1.9891 0.0 0
M  V30 15 C 7.5683 0.291 0.0 0
M  V30 16 C 8.8418 -3.4688 0.0 0
M  V30 17 C 10.1517 -1.1886 0.0 0
M  V30 18 C 8.8418 1.0915 0.0 0
M  V30 19 C 10.1153 -4.1965 0.0 0
M  V30 20 C 7.4955 -4.1965 0.0 0
M  V30 21 C 10.1153 0.3638 0.0 0
M  V30 22 O 11.3888 -3.396 0.0 0
M  V30 23 O 10.0789 -5.6762 0.0 0
M  V30 24 O 6.1492 -3.396 0.0 0
M  V30 25 C 11.3524 -6.416 0.0 0
M  V30 26 C 4.8029 -4.1237 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 8 10
M  V30 10 2 8 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 1 16 19
M  V30 19 2 16 20
M  V30 20 2 17 21
M  V30 21 2 19 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 9 11
M  V30 27 1 18 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000113A1-20220106-C00009

>  <Row No>
79

$$$$
US20220000113A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -0.0356 1.5211 0.0 0
M  V30 3 F 1.2121 0.7962 0.0 0
M  V30 4 C -1.3548 2.2817 0.0 0
M  V30 5 C 1.2121 2.2817 0.0 0
M  V30 6 C -2.6739 1.5568 0.0 0
M  V30 7 C -1.3904 3.8029 0.0 0
M  V30 8 C -3.993 2.3174 0.0 0
M  V30 9 C -2.7096 4.5754 0.0 0
M  V30 10 C -5.3122 1.5924 0.0 0
M  V30 11 C -4.0287 3.8386 0.0 0
M  V30 12 N -6.6313 2.353 0.0 0
M  V30 13 C -5.3478 0.1426 0.0 0
M  V30 14 O -7.9505 1.6281 0.0 0
M  V30 15 C -9.2696 2.3887 0.0 0
M  V30 16 C -10.5888 1.6637 0.0 0
M  V30 17 C -11.9079 2.4243 0.0 0
M  V30 18 C -10.6244 0.2139 0.0 0
M  V30 19 C -11.9436 3.9455 0.0 0
M  V30 20 C -13.2271 1.6994 0.0 0
M  V30 21 C -11.9436 -0.4991 0.0 0
M  V30 22 N -13.2627 4.718 0.0 0
M  V30 23 C -10.6957 4.718 0.0 0
M  V30 24 C -13.2627 0.2495 0.0 0
M  V30 25 O -14.5819 3.993 0.0 0
M  V30 26 O -10.7314 6.2392 0.0 0
M  V30 27 O -9.4479 3.993 0.0 0
M  V30 28 C -15.901 4.7655 0.0 0
M  V30 29 C -8.2001 4.7655 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 8 10
M  V30 10 2 8 11
M  V30 11 2 10 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 17 20
M  V30 20 2 18 21
M  V30 21 2 19 22
M  V30 22 1 19 23
M  V30 23 2 20 24
M  V30 24 1 22 25
M  V30 25 2 23 26
M  V30 26 1 23 27
M  V30 27 1 25 28
M  V30 28 1 27 29
M  V30 29 1 9 11
M  V30 30 1 21 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000113A1-20220106-C00010

>  <Row No>
80

$$$$
US20220000113A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 32 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0354 1.5137 0.0 0
M  V30 3 O 1.2062 2.2824 0.0 0
M  V30 4 C -1.3481 2.2824 0.0 0
M  V30 5 C 2.448 1.561 0.0 0
M  V30 6 C -1.3836 3.7962 0.0 0
M  V30 7 C -2.6608 1.561 0.0 0
M  V30 8 C -2.6963 4.553 0.0 0
M  V30 9 C -0.1419 4.553 0.0 0
M  V30 10 O -3.9736 2.3297 0.0 0
M  V30 11 O -4.009 3.8316 0.0 0
M  V30 12 C -2.7318 6.0668 0.0 0
M  V30 13 C -0.1773 6.0668 0.0 0
M  V30 14 C -5.2863 1.6083 0.0 0
M  V30 15 C -5.3217 4.6003 0.0 0
M  V30 16 C -1.4901 6.8355 0.0 0
M  V30 17 N -5.3572 6.1141 0.0 0
M  V30 18 C -6.6345 3.8789 0.0 0
M  V30 19 C -6.6699 6.8828 0.0 0
M  V30 20 C -7.9472 4.6358 0.0 0
M  V30 21 N -7.9826 6.1614 0.0 0
M  V30 22 O -9.2599 3.9144 0.0 0
M  V30 23 C -10.5726 4.6713 0.0 0
M  V30 24 C -11.8853 3.9499 0.0 0
M  V30 25 C -10.6081 6.1851 0.0 0
M  V30 26 C -11.9208 2.5071 0.0 0
M  V30 27 C -13.198 4.7068 0.0 0
M  V30 28 C -11.9208 6.9538 0.0 0
M  V30 29 N -11.9562 1.0643 0.0 0
M  V30 30 C -13.2335 6.2205 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 8 12
M  V30 12 2 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 2 12 16
M  V30 16 2 15 17
M  V30 17 1 15 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 2 19 21
M  V30 21 1 20 22
M  V30 22 1 22 23
M  V30 23 2 23 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 24 27
M  V30 27 2 25 28
M  V30 28 3 26 29
M  V30 29 2 27 30
M  V30 30 1 13 16
M  V30 31 1 20 21
M  V30 32 1 28 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000113A1-20220106-C00011

>  <Row No>
81

$$$$
US20220000113A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 32 35 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7229 -1.2651 0.0 0
M  V30 3 C -0.0481 -2.5302 0.0 0
M  V30 4 C 2.1928 -1.2289 0.0 0
M  V30 5 O -1.5904 -2.4941 0.0 0
M  V30 6 C 0.6747 -3.7953 0.0 0
M  V30 7 C 2.9158 -2.4941 0.0 0
M  V30 8 C -2.3615 -3.7592 0.0 0
M  V30 9 C 2.1447 -3.7592 0.0 0
M  V30 10 N -1.6386 -5.0243 0.0 0
M  V30 11 C -3.9038 -3.7231 0.0 0
M  V30 12 C -2.4097 -6.2895 0.0 0
M  V30 13 F -4.6749 -2.3856 0.0 0
M  V30 14 C -4.6749 -4.9882 0.0 0
M  V30 15 N -3.952 -6.2533 0.0 0
M  V30 16 O -6.2172 -4.952 0.0 0
M  V30 17 C -6.9883 -6.2172 0.0 0
M  V30 18 C -8.5306 -6.181 0.0 0
M  V30 19 C -6.2654 -7.4823 0.0 0
M  V30 20 C -9.3017 -4.8436 0.0 0
M  V30 21 C -9.3017 -7.4462 0.0 0
M  V30 22 C -7.0485 -8.7474 0.0 0
M  V30 23 N -10.8439 -4.8075 0.0 0
M  V30 24 C -8.5788 -3.5062 0.0 0
M  V30 25 C -8.5788 -8.7113 0.0 0
M  V30 26 O -11.6151 -6.0726 0.0 0
M  V30 27 O -9.3619 -2.1687 0.0 0
M  V30 28 N -7.1088 -3.47 0.0 0
M  V30 29 C -13.1573 -6.0364 0.0 0
M  V30 30 C -8.639 -0.8313 0.0 0
M  V30 31 O -6.3859 -2.1326 0.0 0
M  V30 32 C -7.169 -0.7952 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 2 11 14
M  V30 14 2 12 15
M  V30 15 1 14 16
M  V30 16 1 16 17
M  V30 17 2 17 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 2 19 22
M  V30 22 2 20 23
M  V30 23 1 20 24
M  V30 24 2 21 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 2 24 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 28 31
M  V30 31 1 30 32
M  V30 32 1 7 9
M  V30 33 1 14 15
M  V30 34 1 22 25
M  V30 35 1 31 32
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000113A1-20220106-C00012

>  <Row No>
82

$$$$
US20220000113A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.2574 0.7664 0.0 0
M  V30 3 N 2.5148 0.0479 0.0 0
M  V30 4 C 1.2215 2.2993 0.0 0
M  V30 5 C 3.7722 0.8263 0.0 0
M  V30 6 C -0.1077 3.0657 0.0 0
M  V30 7 C 2.4789 3.0657 0.0 0
M  V30 8 C 3.7363 2.3591 0.0 0
M  V30 9 O -1.437 2.3472 0.0 0
M  V30 10 N -0.1437 4.5986 0.0 0
M  V30 11 C -1.4729 5.365 0.0 0
M  V30 12 C -1.5089 6.8979 0.0 0
M  V30 13 C -2.8022 4.6465 0.0 0
M  V30 14 C -0.2514 7.6643 0.0 0
M  V30 15 C -2.8382 7.6643 0.0 0
M  V30 16 C -4.1315 5.4249 0.0 0
M  V30 17 C -0.2874 9.1972 0.0 0
M  V30 18 C 1.0059 6.9458 0.0 0
M  V30 19 C -4.1674 6.9458 0.0 0
M  V30 20 C 0.97 9.9636 0.0 0
M  V30 21 C 2.2633 7.7242 0.0 0
M  V30 22 C 2.2274 9.2451 0.0 0
M  V30 23 C 3.4848 10.0235 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 10 11
M  V30 11 2 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 12 15
M  V30 15 2 13 16
M  V30 16 2 14 17
M  V30 17 1 14 18
M  V30 18 2 15 19
M  V30 19 1 17 20
M  V30 20 2 18 21
M  V30 21 2 20 22
M  V30 22 1 22 23
M  V30 23 1 7 8
M  V30 24 1 16 19
M  V30 25 1 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000113A1-20220106-C00013

>  <Row No>
83

$$$$
US20220000113A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 52 58 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 1.388 0.3674 0.0 0
M  V30 3 F 1.7962 1.837 0.0 0
M  V30 4 C 2.3473 -0.694 0.0 0
M  V30 5 N 1.9799 -2.082 0.0 0
M  V30 6 C 3.7558 -0.4694 0.0 0
M  V30 7 N 3.225 -2.776 0.0 0
M  V30 8 C 4.4498 0.8573 0.0 0
M  V30 9 C 4.3069 -1.7554 0.0 0
M  V30 10 C 3.3271 -4.1844 0.0 0
M  V30 11 O 3.6333 2.184 0.0 0
M  V30 12 N 5.8582 0.9185 0.0 0
M  V30 13 C 6.5522 2.2453 0.0 0
M  V30 14 C 7.9606 2.3065 0.0 0
M  V30 15 C 5.7357 3.572 0.0 0
M  V30 16 C 8.6546 3.6333 0.0 0
M  V30 17 C 9.2058 1.6125 0.0 0
M  V30 18 C 6.4297 4.8988 0.0 0
M  V30 19 C 7.8381 4.9601 0.0 0
M  V30 20 C 9.8998 2.9393 0.0 0
M  V30 21 C 11.3694 2.9393 0.0 0
M  V30 22 C 9.8998 0.3674 0.0 0
M  V30 23 C 10.5938 1.6941 0.0 0
M  V30 24 C 12.3696 1.9391 0.0 0
M  V30 25 C 11.9205 0.5715 0.0 0
M  V30 26 C 13.7372 2.3882 0.0 0
M  V30 27 F -0.4898 20.9018 0.0 0
M  V30 28 C 0.8981 21.2692 0.0 0
M  V30 29 F 1.3063 22.7389 0.0 0
M  V30 30 C 1.8574 20.2078 0.0 0
M  V30 31 N 1.49 18.8198 0.0 0
M  V30 32 C 3.2659 20.4323 0.0 0
M  V30 33 N 2.7352 18.1258 0.0 0
M  V30 34 C 3.9599 21.7591 0.0 0
M  V30 35 C 3.817 19.1464 0.0 0
M  V30 36 C 2.8372 16.7174 0.0 0
M  V30 37 O 3.1434 23.0859 0.0 0
M  V30 38 N 5.3683 21.8204 0.0 0
M  V30 39 C 6.0623 23.1471 0.0 0
M  V30 40 C 7.4707 23.2084 0.0 0
M  V30 41 C 5.2458 24.4739 0.0 0
M  V30 42 C 8.1647 24.5351 0.0 0
M  V30 43 C 8.7159 22.5144 0.0 0
M  V30 44 C 5.9398 25.8007 0.0 0
M  V30 45 C 7.3483 25.8619 0.0 0
M  V30 46 C 9.4099 23.8411 0.0 0
M  V30 47 C 10.8795 23.8411 0.0 0
M  V30 48 C 9.4099 21.2692 0.0 0
M  V30 49 C 10.1039 22.596 0.0 0
M  V30 50 C 11.2061 25.3312 0.0 0
M  V30 51 C 10.0835 26.4539 0.0 0
M  V30 52 C 12.5737 25.7803 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 2 16 19
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 1 17 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 24 25
M  V30 25 1 24 26
M  V30 26 1 27 28
M  V30 27 1 28 29
M  V30 28 1 28 30
M  V30 29 2 30 31
M  V30 30 1 30 32
M  V30 31 1 31 33
M  V30 32 1 32 34
M  V30 33 2 32 35
M  V30 34 1 33 36
M  V30 35 2 34 37
M  V30 36 1 34 38
M  V30 37 1 38 39
M  V30 38 2 39 40
M  V30 39 1 39 41
M  V30 40 1 40 42
M  V30 41 1 40 43
M  V30 42 2 41 44
M  V30 43 2 42 45
M  V30 44 1 42 46
M  V30 45 1 43 47
M  V30 46 1 43 48
M  V30 47 1 46 49
M  V30 48 1 47 50
M  V30 49 1 50 51
M  V30 50 1 50 52
M  V30 51 1 7 9
M  V30 52 1 18 19
M  V30 53 1 20 21
M  V30 54 1 22 23
M  V30 55 1 33 35
M  V30 56 1 44 45
M  V30 57 1 46 47
M  V30 58 1 48 49
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000113A1-20220106-C00014

>  <Row No>
84

$$$$
US20220000113A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -0.0356 1.5193 0.0 0
M  V30 3 C -1.3531 2.279 0.0 0
M  V30 4 C 1.2107 2.279 0.0 0
M  V30 5 F -2.6707 1.5549 0.0 0
M  V30 6 C -1.3887 3.7983 0.0 0
M  V30 7 C 1.1751 3.7983 0.0 0
M  V30 8 C 2.457 1.5549 0.0 0
M  V30 9 C -0.1424 4.5699 0.0 0
M  V30 10 C -0.178 6.0892 0.0 0
M  V30 11 C -1.4956 6.8489 0.0 0
M  V30 12 C 1.0682 6.8489 0.0 0
M  V30 13 N -2.8131 6.1367 0.0 0
M  V30 14 C -1.5312 8.3683 0.0 0
M  V30 15 C 1.0326 8.3683 0.0 0
M  V30 16 C -4.1307 6.8964 0.0 0
M  V30 17 C -0.2848 9.1398 0.0 0
M  V30 18 O -4.1663 8.4158 0.0 0
M  V30 19 C -5.4483 6.1842 0.0 0
M  V30 20 C -6.837 6.837 0.0 0
M  V30 21 C -5.6382 4.7479 0.0 0
M  V30 22 N -7.8579 5.7806 0.0 0
M  V30 23 C -7.1813 8.3208 0.0 0
M  V30 24 N -7.1219 4.4749 0.0 0
M  V30 25 F -8.6294 8.8193 0.0 0
M  V30 26 F -6.1249 9.3416 0.0 0
M  V30 27 C -7.7748 3.1574 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 2 6 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 16 19
M  V30 19 1 19 20
M  V30 20 2 19 21
M  V30 21 2 20 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 7 9
M  V30 28 1 15 17
M  V30 29 1 22 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00035001.cdx

>  <name>
US20220000113A1-20220106-C00015

>  <Row No>
85

$$$$
US20220000113A1-20220106-C00016
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 C -1.3895 0.6476 0.0 0
M  V30 3 C 0.9538 1.1305 0.0 0
M  V30 4 C -1.2718 2.155 0.0 0
M  V30 5 C -2.7084 -0.0588 0.0 0 CFG=2
M  V30 6 C 0.1884 2.4494 0.0 0
M  V30 7 N -2.4023 3.1795 0.0 0
M  V30 8 C -4.0274 0.7065 0.0 0
M  V30 9 C -2.7438 -1.5073 0.0 0
M  V30 10 C -2.1314 4.6633 0.0 0
M  V30 11 C -5.3463 0.0 0.0 0
M  V30 12 O -0.7536 5.1579 0.0 0
M  V30 13 C -3.2148 5.7467 0.0 0
M  V30 14 C -5.3816 -1.4484 0.0 0
M  V30 15 C -6.6652 0.7654 0.0 0
M  V30 16 C -4.7104 5.5465 0.0 0
M  V30 17 C -3.0146 7.2422 0.0 0
M  V30 18 N -5.4287 6.9007 0.0 0
M  V30 19 C -5.4758 4.2982 0.0 0
M  V30 20 N -4.3689 7.9606 0.0 0
M  V30 21 F -6.9478 3.9449 0.0 0
M  V30 22 F -4.7692 3.0499 0.0 0
M  V30 23 F -6.2413 3.0499 0.0 0
M  V30 24 C -4.7928 9.4326 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 2 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9 CFG=1
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 2 10 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 11 15
M  V30 15 1 13 16
M  V30 16 2 13 17
M  V30 17 2 16 18
M  V30 18 1 16 19
M  V30 19 1 17 20
M  V30 20 1 19 21
M  V30 21 1 19 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 4 6
M  V30 25 1 18 20
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 5)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000113A1-20220106-C00016

>  <Row No>
86

$$$$
US20220000113A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.4249 -0.3273 0.0 0
M  V30 3 Cl 2.4262 0.7895 0.0 0
M  V30 4 C 1.7523 -1.7523 0.0 0
M  V30 5 C 2.3877 -2.8691 0.0 0
M  V30 6 C 1.6367 -4.1786 0.0 0
M  V30 7 C 3.7549 -3.1965 0.0 0
M  V30 8 C 0.905 -3.235 0.0 0
M  V30 9 C 3.0617 -4.4867 0.0 0
M  V30 10 C 0.1925 -4.4674 0.0 0
M  V30 11 C 5.2184 -3.1387 0.0 0
M  V30 12 C 3.7357 -5.7383 0.0 0
M  V30 13 N 6.316 -2.0796 0.0 0
M  V30 14 C 5.8731 -4.4096 0.0 0
M  V30 15 C 5.1606 -5.6805 0.0 0
M  V30 16 C 7.7025 -2.5033 0.0 0
M  V30 17 O 7.9335 -3.9475 0.0 0
M  V30 18 C 8.7615 -1.4634 0.0 0
M  V30 19 C 10.1865 -1.7138 0.0 0
M  V30 20 C 8.6075 0.077 0.0 0
M  V30 21 N 10.9182 -0.3466 0.0 0
M  V30 22 C 10.7257 -3.0617 0.0 0
M  V30 23 N 9.9554 0.7509 0.0 0
M  V30 24 F 9.7821 -4.1978 0.0 0
M  V30 25 C 12.1892 -3.1772 0.0 0
M  V30 26 C 10.2058 2.3107 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 2 2 4
M  V30 4 1 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 9 12
M  V30 12 1 11 13
M  V30 13 2 11 14
M  V30 14 2 12 15
M  V30 15 1 13 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 18 19
M  V30 19 2 18 20
M  V30 20 2 19 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 2 7 9
M  V30 27 1 8 10
M  V30 28 1 14 15
M  V30 29 1 21 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000113A1-20220106-C00017

>  <Row No>
87

$$$$
US20220000113A1-20220106-C00018
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.461 0.0 0
M  V30 3 C -1.3652 -2.1915 0.0 0
M  V30 4 C 1.2215 -2.1915 0.0 0
M  V30 5 N -2.6945 -1.425 0.0 0
M  V30 6 C -1.4011 -3.6525 0.0 0
M  V30 7 C 1.1855 -3.6525 0.0 0
M  V30 8 C -4.0237 -2.1556 0.0 0
M  V30 9 C -2.7304 0.1077 0.0 0
M  V30 10 C -0.1437 -4.383 0.0 0
M  V30 11 C 2.443 -4.383 0.0 0
M  V30 12 N -5.353 -1.3891 0.0 0
M  V30 13 N -4.0597 -3.6166 0.0 0
M  V30 14 O -1.4729 0.8861 0.0 0
M  V30 15 C -4.0597 0.8861 0.0 0
M  V30 16 C -5.389 0.1437 0.0 0
M  V30 17 N -5.3051 -4.4549 0.0 0
M  V30 18 C -2.8861 -4.4549 0.0 0
M  V30 19 C -4.0956 2.419 0.0 0
M  V30 20 C -6.7182 0.9221 0.0 0
M  V30 21 C -4.874 -5.844 0.0 0
M  V30 22 N -3.389 -5.844 0.0 0
M  V30 23 C -5.4249 3.1974 0.0 0
M  V30 24 C -6.7542 2.4549 0.0 0
M  V30 25 F -5.4608 4.7303 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 8 13
M  V30 13 2 9 14
M  V30 14 1 9 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 1 15 19
M  V30 19 1 16 20
M  V30 20 2 17 21
M  V30 21 2 18 22
M  V30 22 2 19 23
M  V30 23 2 20 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 2 15 16
M  V30 27 1 21 22
M  V30 28 1 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00038001.cdx

>  <name>
US20220000113A1-20220106-C00018

>  <Row No>
88

$$$$
US20220000113A1-20220106-C00019
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3365 -0.7089 0.0 0
M  V30 3 C -1.3714 -2.1734 0.0 0
M  V30 4 C -2.6731 0.0813 0.0 0
M  V30 5 C -2.708 -2.8823 0.0 0
M  V30 6 C -0.1046 -2.8823 0.0 0
M  V30 7 C -4.0097 -0.6276 0.0 0
M  V30 8 C -4.0446 -2.0804 0.0 0
M  V30 9 O 0.7554 -4.0678 0.0 0
M  V30 10 O 0.7554 -1.6271 0.0 0
M  V30 11 C -1.4411 -3.5797 0.0 0
M  V30 12 O -5.3463 0.1627 0.0 0
M  V30 13 C 2.1501 -3.5797 0.0 0
M  V30 14 C 2.1501 -2.0455 0.0 0
M  V30 15 N -1.476 -5.0441 0.0 0
M  V30 16 C -6.6829 -0.5462 0.0 0
M  V30 17 C 3.3356 -4.4398 0.0 0
M  V30 18 N -2.7312 -5.9042 0.0 0
M  V30 19 C -0.2905 -5.9042 0.0 0
M  V30 20 C -6.7178 -2.0106 0.0 0
M  V30 21 C -8.0195 0.244 0.0 0
M  V30 22 C -2.3128 -7.2989 0.0 0
M  V30 23 N -0.7787 -7.2989 0.0 0
M  V30 24 C -8.0544 -2.7196 0.0 0
M  V30 25 C -9.3561 -0.4649 0.0 0
M  V30 26 C -9.391 -1.9177 0.0 0
M  V30 27 Cl -10.7275 -2.6266 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 1 16 21
M  V30 21 2 18 22
M  V30 22 2 19 23
M  V30 23 1 20 24
M  V30 24 2 21 25
M  V30 25 2 24 26
M  V30 26 1 26 27
M  V30 27 1 7 8
M  V30 28 1 13 14
M  V30 29 1 22 23
M  V30 30 1 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00039001.cdx

>  <name>
US20220000113A1-20220106-C00019

>  <Row No>
89

$$$$
US20220000113A1-20220106-C00020
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.5973 -1.3532 0.0 0
M  V30 3 C -0.3291 -2.5479 0.0 0
M  V30 4 C 2.0725 -1.4751 0.0 0
M  V30 5 C 0.2682 -3.9011 0.0 0
M  V30 6 C 2.6698 -2.8283 0.0 0
M  V30 7 C 1.7433 -4.023 0.0 0
M  V30 8 N 2.3407 -5.3763 0.0 0
M  V30 9 N 3.7914 -5.6567 0.0 0
M  V30 10 C 1.5482 -6.6563 0.0 0
M  V30 11 C 3.9133 -7.1318 0.0 0
M  V30 12 C 2.5235 -7.7414 0.0 0
M  V30 13 O 5.1934 -7.8633 0.0 0
M  V30 14 C 6.4735 -7.083 0.0 0
M  V30 15 C 7.7536 -7.8145 0.0 0
M  V30 16 C 9.0336 -7.0221 0.0 0
M  V30 17 C 7.717 -9.3018 0.0 0
M  V30 18 N 8.9971 -5.4616 0.0 0
M  V30 19 C 10.3137 -7.7536 0.0 0
M  V30 20 C 8.9971 -10.0333 0.0 0
M  V30 21 O 10.2771 -4.6692 0.0 0
M  V30 22 C 7.6438 -4.6692 0.0 0
M  V30 23 C 10.2771 -9.2409 0.0 0
M  V30 24 C 11.5572 -5.4007 0.0 0
M  V30 25 O 6.2906 -5.4007 0.0 0
M  V30 26 O 7.6073 -3.1087 0.0 0
M  V30 27 C 6.254 -2.3163 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 8 10
M  V30 10 2 9 11
M  V30 11 2 10 12
M  V30 12 1 11 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 2 17 20
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 2 19 23
M  V30 23 1 21 24
M  V30 24 2 22 25
M  V30 25 1 22 26
M  V30 26 1 26 27
M  V30 27 1 6 7
M  V30 28 1 11 12
M  V30 29 1 20 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00040001.cdx

>  <name>
US20220000113A1-20220106-C00020

>  <Row No>
90

$$$$
US20220000113A1-20220106-C00021
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3339 -0.721 0.0 0
M  V30 3 C -1.3699 -2.1871 0.0 0
M  V30 4 C -2.6678 0.048 0.0 0
M  V30 5 N -2.7038 -2.9201 0.0 0
M  V30 6 C -0.1081 -2.9201 0.0 0
M  V30 7 C -4.0017 -0.6729 0.0 0
M  V30 8 C -4.0377 -2.139 0.0 0
M  V30 9 C 1.1536 -2.139 0.0 0
M  V30 10 C -5.3356 0.0961 0.0 0
M  V30 11 N 2.4154 -2.8721 0.0 0
M  V30 12 F -6.6695 -0.6248 0.0 0
M  V30 13 F -6.6695 0.8772 0.0 0
M  V30 14 F -5.3716 1.6343 0.0 0
M  V30 15 C 3.6772 -2.0909 0.0 0
M  V30 16 O 3.6412 -0.5527 0.0 0
M  V30 17 C 4.939 -2.824 0.0 0
M  V30 18 C 6.2008 -2.0549 0.0 0
M  V30 19 C 4.903 -4.2901 0.0 0
M  V30 20 C 7.4626 -2.7879 0.0 0
M  V30 21 C 6.1648 -0.5167 0.0 0
M  V30 22 C 6.1648 -5.0231 0.0 0
M  V30 23 C 7.4266 -4.254 0.0 0
M  V30 24 F 4.8309 0.2523 0.0 0
M  V30 25 F 6.1287 1.0214 0.0 0
M  V30 26 C 7.4266 0.2523 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 2 17 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 2 19 22
M  V30 22 2 20 23
M  V30 23 1 21 24
M  V30 24 1 21 25
M  V30 25 1 21 26
M  V30 26 1 7 8
M  V30 27 1 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00041001.cdx

>  <name>
US20220000113A1-20220106-C00021

>  <Row No>
91

$$$$
US20220000113A1-20220106-C00022
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -0.0361 -1.4681 0.0 0
M  V30 3 C -1.3718 -2.2021 0.0 0
M  V30 4 C 1.2274 -2.2021 0.0 0
M  V30 5 C -1.4079 -3.6703 0.0 0
M  V30 6 C -2.7076 -1.432 0.0 0 CFG=1
M  V30 7 C 1.1913 -3.6703 0.0 0
M  V30 8 C -0.1444 -4.4043 0.0 0
M  V30 9 O -1.444 -0.6498 0.0 0
M  V30 10 C -2.7437 0.1083 0.0 0
M  V30 11 C -4.0433 -2.166 0.0 0
M  V30 12 C -4.0794 0.8784 0.0 0
M  V30 13 C -1.4801 0.8784 0.0 0
M  V30 14 N -4.0794 -3.6342 0.0 0
M  V30 15 C -4.1155 2.4188 0.0 0
M  V30 16 C -1.5162 2.4188 0.0 0
M  V30 17 N -5.3309 -4.4765 0.0 0
M  V30 18 C -2.9001 -4.4765 0.0 0
M  V30 19 C -2.852 3.1889 0.0 0
M  V30 20 C -4.8977 -5.8725 0.0 0
M  V30 21 N -3.4055 -5.8725 0.0 0
M  V30 22 F -2.8881 4.7293 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9 CFG=1
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 2 10 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 2 13 16
M  V30 16 1 14 17
M  V30 17 1 14 18
M  V30 18 2 15 19
M  V30 19 2 17 20
M  V30 20 2 18 21
M  V30 21 1 19 22
M  V30 22 1 7 8
M  V30 23 1 16 19
M  V30 24 1 20 21
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 6)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00042001.cdx

>  <name>
US20220000113A1-20220106-C00022

>  <Row No>
92

$$$$
US20220000113A1-20220106-C00023
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0357 1.5244 0.0 0
M  V30 3 O -1.3577 2.2985 0.0 0
M  V30 4 C 1.2147 2.2985 0.0 0
M  V30 5 C -2.6797 1.584 0.0 0
M  V30 6 N 2.4653 1.584 0.0 0
M  V30 7 C 1.179 3.823 0.0 0
M  V30 8 O 3.7158 2.3581 0.0 0
M  V30 9 C -0.1429 4.5971 0.0 0
M  V30 10 C 2.4295 4.5971 0.0 0
M  V30 11 C 4.9663 1.6435 0.0 0
M  V30 12 C -0.1786 6.1216 0.0 0
M  V30 13 C -1.4649 3.8825 0.0 0
M  V30 14 C 2.3938 6.1216 0.0 0
M  V30 15 C 1.0718 6.8838 0.0 0
M  V30 16 O -2.7868 4.6567 0.0 0
M  V30 17 C -4.1088 3.9421 0.0 0
M  V30 18 C -5.4308 4.7162 0.0 0
M  V30 19 C -4.1446 2.4891 0.0 0
M  V30 20 C -6.7528 4.0016 0.0 0
M  V30 21 C -5.4665 6.2407 0.0 0
M  V30 22 C -5.4665 1.7626 0.0 0
M  V30 23 C -6.7885 2.5486 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 12 15
M  V30 15 1 13 16
M  V30 16 1 16 17
M  V30 17 2 17 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 2 19 22
M  V30 22 2 20 23
M  V30 23 1 14 15
M  V30 24 1 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00043001.cdx

>  <name>
US20220000113A1-20220106-C00023

>  <Row No>
93

$$$$
US20220000113A1-20220106-C00024
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 14 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.2672 0.7724 0.0 0
M  V30 3 C 1.231 2.3172 0.0 0
M  V30 4 C 2.5345 0.0482 0.0 0
M  V30 5 Cl -0.1086 3.1017 0.0 0
M  V30 6 C 2.4982 3.1017 0.0 0
M  V30 7 Cl 2.4982 -1.4241 0.0 0
M  V30 8 C 3.8017 0.8327 0.0 0
M  V30 9 C 2.462 4.6465 0.0 0
M  V30 10 C 3.7655 2.3776 0.0 0
M  V30 11 C 5.069 0.1086 0.0 0
M  V30 12 N 2.4258 6.1914 0.0 0
M  V30 13 Cl 5.0328 3.162 0.0 0
M  V30 14 C 6.3362 -0.6155 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 1 8 11
M  V30 11 3 9 12
M  V30 12 1 10 13
M  V30 13 3 11 14
M  V30 14 1 8 10
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00044001.cdx

>  <name>
US20220000113A1-20220106-C00024

>  <Row No>
94

$$$$
US20220000113A1-20220106-C00025
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 9 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Mn 0.0 0.0 0.0 0 CHG=2
M  V30 2 S -1.6049 -3.493 0.0 0
M  V30 3 C -1.6403 -1.9825 0.0 0
M  V30 4 S -0.4012 -1.2154 0.0 0 CHG=-1
M  V30 5 C -2.9501 -1.2154 0.0 0
M  V30 6 C -4.26 -1.9235 0.0 0
M  V30 7 C -5.5699 -1.1564 0.0 0
M  V30 8 N -6.8798 -1.8645 0.0 0
M  V30 9 C -8.1897 -1.0974 0.0 0
M  V30 10 S -8.2251 0.413 0.0 0
M  V30 11 NOT[S] -9.4996 -1.8055 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 2 3
M  V30 2 1 3 4
M  V30 3 1 3 5
M  V30 4 1 5 6
M  V30 5 1 6 7
M  V30 6 1 7 8
M  V30 7 1 8 9
M  V30 8 2 9 10
M  V30 9 1 9 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00045001.cdx

>  <name>
US20220000113A1-20220106-C00025

>  <Row No>
95

$$$$
US20220000113A1-20220106-C00026
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.7225 -1.2645 0.0 0
M  V30 3 O -0.7707 1.3367 0.0 0
M  V30 4 N -1.3367 -0.7225 0.0 0
M  V30 5 C 1.2645 0.7707 0.0 0
M  V30 6 C -1.3729 -2.1918 0.0 0
M  V30 7 C -2.6735 0.0481 0.0 0
M  V30 8 C 1.2284 2.3122 0.0 0
M  V30 9 C 2.529 0.0481 0.0 0
M  V30 10 O -0.1083 -2.9144 0.0 0
M  V30 11 N -2.7097 -2.9144 0.0 0
M  V30 12 C -4.0103 -0.6744 0.0 0
M  V30 13 C 2.4929 3.095 0.0 0
M  V30 14 C 3.7936 0.8309 0.0 0
M  V30 15 C -4.0465 -2.1316 0.0 0
M  V30 16 C -2.7458 -4.3837 0.0 0
M  V30 17 F -5.3471 0.0963 0.0 0
M  V30 18 C 3.7574 2.3604 0.0 0
M  V30 19 N -5.3833 -2.8542 0.0 0
M  V30 20 C 5.022 3.1432 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 6 11
M  V30 11 2 7 12
M  V30 12 1 8 13
M  V30 13 2 9 14
M  V30 14 1 11 15
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 18 20
M  V30 20 1 12 15
M  V30 21 1 14 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00048001.cdx

>  <name>
US20220000113A1-20220106-C00026

>  <Row No>
96

$$$$
US20220000114A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.7695 1.3347 0.0 0
M  V30 3 O 0.7214 -1.2625 0.0 0
M  V30 4 N -1.3347 -0.7214 0.0 0
M  V30 5 C 1.2505 0.7816 0.0 0
M  V30 6 C -1.3708 -2.1885 0.0 0
M  V30 7 C -2.6694 0.0601 0.0 0
M  V30 8 C 1.2144 2.3207 0.0 0
M  V30 9 C 2.5131 0.0601 0.0 0
M  V30 10 O -0.1202 -2.922 0.0 0
M  V30 11 N -2.7055 -2.922 0.0 0
M  V30 12 C -4.0042 -0.6613 0.0 0
M  V30 13 C 2.477 3.1023 0.0 0
M  V30 14 C 3.7757 0.8417 0.0 0
M  V30 15 C -4.0403 -2.1404 0.0 0
M  V30 16 C -2.7416 -4.389 0.0 0
M  V30 17 F -5.351 0.1082 0.0 0
M  V30 18 C 3.7396 2.3688 0.0 0
M  V30 19 N -5.375 -2.8618 0.0 0
M  V30 20 C 5.0143 3.1504 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 6 11
M  V30 11 2 7 12
M  V30 12 1 8 13
M  V30 13 2 9 14
M  V30 14 1 11 15
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 18 20
M  V30 20 1 12 15
M  V30 21 1 14 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000114A1-20220106-C00001

>  <Row No>
97

$$$$
US20220000114A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.7695 1.3347 0.0 0
M  V30 3 O 0.7214 -1.2625 0.0 0
M  V30 4 N -1.3347 -0.7214 0.0 0
M  V30 5 C 1.2505 0.7816 0.0 0
M  V30 6 C -1.3708 -2.1885 0.0 0
M  V30 7 C -2.6694 0.0601 0.0 0
M  V30 8 C 1.2144 2.3207 0.0 0
M  V30 9 C 2.5131 0.0601 0.0 0
M  V30 10 O -0.1202 -2.922 0.0 0
M  V30 11 N -2.7055 -2.922 0.0 0
M  V30 12 C -4.0042 -0.6613 0.0 0
M  V30 13 C 2.477 3.1023 0.0 0
M  V30 14 C 3.7757 0.8417 0.0 0
M  V30 15 C -4.0403 -2.1404 0.0 0
M  V30 16 C -2.7416 -4.389 0.0 0
M  V30 17 F -5.351 0.1082 0.0 0
M  V30 18 C 3.7396 2.3688 0.0 0
M  V30 19 N -5.375 -2.8618 0.0 0
M  V30 20 C 5.0143 3.1504 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 6 11
M  V30 11 2 7 12
M  V30 12 1 8 13
M  V30 13 2 9 14
M  V30 14 1 11 15
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 18 20
M  V30 20 1 12 15
M  V30 21 1 14 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000114A1-20220106-C00002

>  <Row No>
98

$$$$
US20220000114A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0119 -1.4609 0.0 0
M  V30 3 C -1.3411 -2.1793 0.0 0
M  V30 4 C 1.2453 -2.1793 0.0 0
M  V30 5 C -1.377 -3.6403 0.0 0
M  V30 6 C -2.6823 -1.413 0.0 0 CFG=1
M  V30 7 C 1.2094 -3.6403 0.0 0
M  V30 8 C -0.1197 -4.3707 0.0 0
M  V30 9 O -3.4606 -0.0838 0.0 0
M  V30 10 C -4.215 -1.377 0.0 0 CFG=2
M  V30 11 C -5.3526 -0.3352 0.0 0
M  V30 12 C -5.5323 -2.1195 0.0 0
M  V30 13 C -5.0533 1.1615 0.0 0
M  V30 14 C -6.8136 -0.7424 0.0 0
M  V30 15 N -5.5442 -3.5804 0.0 0
M  V30 16 C -6.1789 2.2033 0.0 0
M  V30 17 C -7.9392 0.2993 0.0 0
M  V30 18 N -6.7896 -4.4186 0.0 0
M  V30 19 C -4.3707 -4.4186 0.0 0
M  V30 20 C -7.6398 1.7962 0.0 0
M  V30 21 C -6.3585 -5.8077 0.0 0
M  V30 22 N -4.8737 -5.8077 0.0 0
M  V30 23 F -8.7654 2.8499 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 6 3 CFG=3
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 10 11
M  V30 11 1 10 12 CFG=3
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 2 18 21
M  V30 21 2 19 22
M  V30 22 1 20 23
M  V30 23 1 7 8
M  V30 24 1 9 10
M  V30 25 1 17 20
M  V30 26 1 21 22
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 6 10)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000114A1-20220106-C00003

>  <Row No>
99

$$$$
US20220000114A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0352 -1.4798 0.0 0
M  V30 3 C -1.3858 -2.1962 0.0 0
M  V30 4 C 1.2449 -2.1962 0.0 0
M  V30 5 C -1.421 -3.676 0.0 0
M  V30 6 C 1.2096 -3.676 0.0 0
M  V30 7 C -0.1409 -4.4159 0.0 0
M  V30 8 C -0.1761 -5.8957 0.0 0
M  V30 9 O -1.5385 -5.1441 0.0 0
M  V30 10 C 1.1157 -6.5887 0.0 0
M  V30 11 C -1.5267 -6.6122 0.0 0
M  V30 12 C 1.057 -8.0685 0.0 0
M  V30 13 C 2.3841 -5.7666 0.0 0
M  V30 14 N -1.562 -8.092 0.0 0
M  V30 15 C 0.2583 -9.3487 0.0 0
M  V30 16 C 1.7851 -9.3487 0.0 0
M  V30 17 N -2.8304 -8.9611 0.0 0
M  V30 18 C -0.364 -8.9611 0.0 0
M  V30 19 C -2.4076 -10.3704 0.0 0
M  V30 20 N -0.8573 -10.3704 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 8 10
M  V30 10 1 8 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 1 14 17
M  V30 17 1 14 18
M  V30 18 2 17 19
M  V30 19 2 18 20
M  V30 20 1 6 7
M  V30 21 1 15 16
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000114A1-20220106-C00004

>  <Row No>
100

$$$$
US20220000114A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.2851 -0.7274 0.0 0
M  V30 3 C 1.2487 -2.2187 0.0 0
M  V30 4 C 2.5703 0.0606 0.0 0
M  V30 5 C 2.5339 -2.9461 0.0 0
M  V30 6 C 3.8554 -0.6789 0.0 0
M  V30 7 C 3.8191 -2.1581 0.0 0
M  V30 8 C 5.1042 -2.8976 0.0 0
M  V30 9 C 6.4015 -2.1096 0.0 0
M  V30 10 C 7.7594 -2.7036 0.0 0
M  V30 11 C 6.5227 -0.5577 0.0 0
M  V30 12 O 9.1901 -3.1159 0.0 0
M  V30 13 C 8.7415 -1.5397 0.0 0
M  V30 14 C 8.0019 -4.1707 0.0 0
M  V30 15 C 7.9776 -0.2061 0.0 0
M  V30 16 C 9.5659 -0.2424 0.0 0
M  V30 17 C 10.2206 -1.7095 0.0 0
M  V30 18 N 9.4083 -4.6193 0.0 0
M  V30 19 N 9.8448 -6.0378 0.0 0
M  V30 20 C 10.6086 -3.6857 0.0 0
M  V30 21 C 11.336 -6.0014 0.0 0
M  V30 22 C 11.8089 -4.5465 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 13 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 2 19 21
M  V30 21 2 20 22
M  V30 22 1 6 7
M  V30 23 1 13 15
M  V30 24 1 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000114A1-20220106-C00005

>  <Row No>
101

$$$$
US20220000114A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7025 -1.2762 0.0 0
M  V30 3 C 2.1778 -1.2411 0.0 0
M  V30 4 C -0.1053 -2.5525 0.0 0
M  V30 5 C 2.9037 -2.5173 0.0 0
M  V30 6 C 0.6088 -3.8287 0.0 0
M  V30 7 C 2.0958 -3.7936 0.0 0
M  V30 8 C 2.8452 -5.0581 0.0 0 CFG=1
M  V30 9 C 4.1214 -4.262 0.0 0
M  V30 10 C 3.5828 -6.3344 0.0 0
M  V30 11 C 1.5104 -5.7841 0.0 0
M  V30 12 N 5.3977 -3.4658 0.0 0
M  V30 13 N 5.0581 -6.2759 0.0 0
M  V30 14 C 0.1639 -4.9762 0.0 0
M  V30 15 N 5.9246 -5.0113 0.0 0
M  V30 16 C 5.9246 -7.4702 0.0 0
M  V30 17 C -1.1825 -5.7021 0.0 0
M  V30 18 C 7.3297 -5.4328 0.0 0
M  V30 19 C 7.3297 -6.9784 0.0 0
M  V30 20 C -2.529 -4.8942 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 8 7 CFG=1
M  V30 8 1 8 9
M  V30 9 1 8 10
M  V30 10 1 8 11
M  V30 11 3 9 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 2 16 19
M  V30 19 1 17 20
M  V30 20 1 6 7
M  V30 21 1 18 19
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 8)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000114A1-20220106-C00006

>  <Row No>
102

$$$$
US20220000114A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3991 -0.5979 0.0 0
M  V30 3 C -1.435 -2.0687 0.0 0
M  V30 4 C -2.7384 0.1913 0.0 0
M  V30 5 C -2.7743 -2.7982 0.0 0
M  V30 6 C -0.2032 -2.846 0.0 0
M  V30 7 C -4.0777 -0.5381 0.0 0
M  V30 8 C -4.1136 -2.009 0.0 0
M  V30 9 O 1.136 -3.432 0.0 0
M  V30 10 O -0.0837 -1.3154 0.0 0
M  V30 11 C -1.5187 -3.5994 0.0 0
M  V30 12 Cl -5.3692 0.3228 0.0 0
M  V30 13 C 2.1046 -2.284 0.0 0
M  V30 14 C 1.3512 -0.9686 0.0 0
M  V30 15 N -1.5785 -5.0703 0.0 0
M  V30 16 C 3.5635 -2.4275 0.0 0
M  V30 17 N -2.8341 -5.9193 0.0 0
M  V30 18 C -0.3946 -5.9193 0.0 0
M  V30 19 C 4.293 -1.0882 0.0 0
M  V30 20 C -2.4036 -7.3185 0.0 0
M  V30 21 N -0.8968 -7.3185 0.0 0
M  V30 22 C 5.716 -1.4469 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 13 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 2 17 20
M  V30 20 2 18 21
M  V30 21 1 19 22
M  V30 22 1 7 8
M  V30 23 1 13 14
M  V30 24 1 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000114A1-20220106-C00007

>  <Row No>
103

$$$$
US20220000114A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.1645 -1.4807 0.0 0
M  V30 3 C 1.0459 -2.3268 0.0 0
M  V30 4 C -1.5747 -2.08 0.0 0
M  V30 5 C 0.8813 -3.8075 0.0 0
M  V30 6 C 2.3268 -1.5277 0.0 0
M  V30 7 C -1.7392 -3.5607 0.0 0
M  V30 8 C -0.5288 -4.4069 0.0 0
M  V30 9 C 3.6077 -2.2328 0.0 0 CFG=1
M  V30 10 O 3.9838 -0.7403 0.0 0
M  V30 11 C 4.8887 -2.9379 0.0 0
M  V30 12 C 2.2563 -2.9379 0.0 0
M  V30 13 Cl 5.2647 -1.4454 0.0 0
M  V30 14 C 6.3694 -2.9026 0.0 0
M  V30 15 C 5.6055 -4.2188 0.0 0
M  V30 16 N 2.221 -4.4186 0.0 0
M  V30 17 N 0.9518 -5.2882 0.0 0
M  V30 18 C 3.4197 -5.2882 0.0 0
M  V30 19 C 1.3749 -6.6984 0.0 0
M  V30 20 S 4.8299 -4.8182 0.0 0
M  V30 21 N 2.9261 -6.6984 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 9 6 CFG=1
M  V30 9 1 9 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 16 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 7 8
M  V30 22 1 14 15
M  V30 23 1 19 21
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 9)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000114A1-20220106-C00008

>  <Row No>
104

$$$$
US20220000114A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 1.2617 0.7886 0.0 0
M  V30 3 F -0.0727 1.5772 0.0 0
M  V30 4 F 1.2132 2.3415 0.0 0
M  V30 5 C 2.5478 0.0606 0.0 0
M  V30 6 N 3.8217 0.8492 0.0 0
M  V30 7 C 2.5114 -1.4194 0.0 0
M  V30 8 C 5.0956 0.1091 0.0 0
M  V30 9 C 3.7853 -2.1595 0.0 0
M  V30 10 O 6.3816 0.8856 0.0 0
M  V30 11 C 5.0592 -1.3709 0.0 0
M  V30 12 C 7.6677 0.1698 0.0 0
M  V30 13 C 8.9416 0.9463 0.0 0
M  V30 14 C 10.2155 0.2183 0.0 0
M  V30 15 C 8.9052 2.4992 0.0 0
M  V30 16 C 10.1548 -1.2617 0.0 0
M  V30 17 C 11.4894 0.9948 0.0 0
M  V30 18 C 10.1791 3.2878 0.0 0
M  V30 19 C 11.4287 -1.9897 0.0 0
M  V30 20 C 8.8203 -2.0018 0.0 0
M  V30 21 C 11.453 2.5478 0.0 0
M  V30 22 O 12.7026 -1.2011 0.0 0
M  V30 23 O 11.3923 -3.4698 0.0 0
M  V30 24 O 7.4614 -1.2253 0.0 0
M  V30 25 C 12.6662 -4.2099 0.0 0
M  V30 26 C 6.1147 -1.9533 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 8 10
M  V30 10 2 8 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 1 16 19
M  V30 19 2 16 20
M  V30 20 2 17 21
M  V30 21 2 19 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 9 11
M  V30 27 1 18 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000114A1-20220106-C00009

>  <Row No>
105

$$$$
US20220000114A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -1.3207 -0.7258 0.0 0
M  V30 3 F -1.3564 -2.1774 0.0 0
M  V30 4 C -2.6415 0.0356 0.0 0
M  V30 5 C -0.0713 -1.4516 0.0 0
M  V30 6 C -3.9622 -0.6782 0.0 0
M  V30 7 C -2.6772 1.5587 0.0 0
M  V30 8 C -5.283 0.0832 0.0 0
M  V30 9 C -3.9979 2.3202 0.0 0
M  V30 10 C -6.6037 -0.6306 0.0 0
M  V30 11 C -5.3187 1.6063 0.0 0
M  V30 12 N -7.9245 0.1308 0.0 0
M  V30 13 C -6.6394 -2.0822 0.0 0
M  V30 14 O -9.2333 -0.5949 0.0 0
M  V30 15 C -10.566 0.1665 0.0 0
M  V30 16 C -11.8868 -0.5473 0.0 0
M  V30 17 C -13.2075 0.2141 0.0 0
M  V30 18 C -11.9225 -1.9989 0.0 0
M  V30 19 C -13.2194 1.7372 0.0 0
M  V30 20 C -14.5283 -0.4997 0.0 0
M  V30 21 C -13.2432 -2.7248 0.0 0
M  V30 22 N -14.5402 2.5106 0.0 0
M  V30 23 C -11.97 2.5106 0.0 0
M  V30 24 C -14.564 -1.9513 0.0 0
M  V30 25 O -15.849 1.7729 0.0 0
M  V30 26 O -12.0176 4.0336 0.0 0
M  V30 27 O -10.7207 1.7848 0.0 0
M  V30 28 C -17.1698 2.5463 0.0 0
M  V30 29 C -9.4713 2.5582 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 8 10
M  V30 10 2 8 11
M  V30 11 2 10 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 17 20
M  V30 20 2 18 21
M  V30 21 2 19 22
M  V30 22 1 19 23
M  V30 23 2 20 24
M  V30 24 1 22 25
M  V30 25 2 23 26
M  V30 26 1 23 27
M  V30 27 1 25 28
M  V30 28 1 27 29
M  V30 29 1 9 11
M  V30 30 1 21 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000114A1-20220106-C00010

>  <Row No>
106

$$$$
US20220000114A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 32 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0355 1.5156 0.0 0
M  V30 3 O 1.2077 2.2852 0.0 0
M  V30 4 C -1.3616 2.2734 0.0 0
M  V30 5 C 2.451 1.5629 0.0 0
M  V30 6 C -1.3735 3.789 0.0 0
M  V30 7 C -2.6878 1.5629 0.0 0
M  V30 8 C -2.6878 4.5468 0.0 0
M  V30 9 C -0.1302 4.5468 0.0 0
M  V30 10 O -3.9903 2.3444 0.0 0
M  V30 11 O -4.014 3.8363 0.0 0
M  V30 12 C -2.7233 6.0624 0.0 0
M  V30 13 C -0.1657 6.0624 0.0 0
M  V30 14 C -5.3164 1.634 0.0 0
M  V30 15 C -5.3164 4.6178 0.0 0
M  V30 16 C -1.48 6.8202 0.0 0
M  V30 17 N -5.352 6.1334 0.0 0
M  V30 18 C -6.6308 3.9074 0.0 0
M  V30 19 C -6.6663 6.8913 0.0 0
M  V30 20 C -7.9451 4.677 0.0 0
M  V30 21 N -7.9806 6.1808 0.0 0
M  V30 22 O -9.2476 3.9429 0.0 0
M  V30 23 C -10.5619 4.7126 0.0 0
M  V30 24 C -11.8762 4.0021 0.0 0
M  V30 25 C -10.5974 6.2282 0.0 0
M  V30 26 C -11.888 2.5575 0.0 0
M  V30 27 C -13.1905 4.7718 0.0 0
M  V30 28 C -11.9117 6.986 0.0 0
M  V30 29 N -11.9236 1.113 0.0 0
M  V30 30 C -13.226 6.2874 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 8 12
M  V30 12 2 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 2 12 16
M  V30 16 2 15 17
M  V30 17 1 15 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 2 19 21
M  V30 21 1 20 22
M  V30 22 1 22 23
M  V30 23 2 23 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 24 27
M  V30 27 2 25 28
M  V30 28 3 26 29
M  V30 29 2 27 30
M  V30 30 1 13 16
M  V30 31 1 20 21
M  V30 32 1 28 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000114A1-20220106-C00011

>  <Row No>
107

$$$$
US20220000114A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 32 35 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7214 -1.2625 0.0 0
M  V30 3 C -0.0601 -2.5251 0.0 0
M  V30 4 C 2.1884 -1.2265 0.0 0
M  V30 5 O -1.5992 -2.5131 0.0 0
M  V30 6 C 0.6613 -3.7877 0.0 0
M  V30 7 C 2.9219 -2.489 0.0 0
M  V30 8 C -2.3688 -3.7877 0.0 0
M  V30 9 C 2.1283 -3.7516 0.0 0
M  V30 10 N -1.6353 -5.0503 0.0 0
M  V30 11 C -3.9079 -3.7516 0.0 0
M  V30 12 C -2.4169 -6.3128 0.0 0
M  V30 13 F -4.7136 -2.4289 0.0 0
M  V30 14 C -4.6895 -5.0142 0.0 0
M  V30 15 N -3.956 -6.2768 0.0 0
M  V30 16 O -6.2287 -4.9781 0.0 0
M  V30 17 C -7.0223 -6.2287 0.0 0
M  V30 18 C -8.5614 -6.1926 0.0 0
M  V30 19 C -6.3008 -7.4912 0.0 0
M  V30 20 C -9.343 -4.8579 0.0 0
M  V30 21 C -9.343 -7.4552 0.0 0
M  V30 22 C -7.0824 -8.7538 0.0 0
M  V30 23 N -10.8822 -4.7977 0.0 0
M  V30 24 C -8.6216 -3.5111 0.0 0
M  V30 25 C -8.6095 -8.7178 0.0 0
M  V30 26 O -11.6638 -6.0603 0.0 0
M  V30 27 O -9.4032 -2.1764 0.0 0
M  V30 28 N -7.1546 -3.475 0.0 0
M  V30 29 C -13.2029 -6.0243 0.0 0
M  V30 30 C -8.6817 -0.8417 0.0 0
M  V30 31 O -6.4331 -2.1403 0.0 0
M  V30 32 C -7.2147 -0.8056 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 2 11 14
M  V30 14 2 12 15
M  V30 15 1 14 16
M  V30 16 1 16 17
M  V30 17 2 17 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 2 19 22
M  V30 22 2 20 23
M  V30 23 1 20 24
M  V30 24 2 21 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 2 24 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 28 31
M  V30 31 1 30 32
M  V30 32 1 7 9
M  V30 33 1 14 15
M  V30 34 1 22 25
M  V30 35 1 31 32
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000114A1-20220106-C00012

>  <Row No>
108

$$$$
US20220000114A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.2572 0.7663 0.0 0
M  V30 3 N 2.5144 0.0478 0.0 0
M  V30 4 C 1.2213 2.2989 0.0 0
M  V30 5 C 3.7716 0.8261 0.0 0
M  V30 6 C -0.1077 3.0652 0.0 0
M  V30 7 C 2.4785 3.0652 0.0 0
M  V30 8 C 3.7357 2.3587 0.0 0
M  V30 9 O -1.4368 2.3468 0.0 0
M  V30 10 N -0.1436 4.5978 0.0 0
M  V30 11 C -1.4727 5.3641 0.0 0
M  V30 12 C -1.5086 6.8967 0.0 0
M  V30 13 C -2.8018 4.6457 0.0 0
M  V30 14 C -0.2514 7.6631 0.0 0
M  V30 15 C -2.8377 7.6631 0.0 0
M  V30 16 C -4.1308 5.424 0.0 0
M  V30 17 C 1.0057 6.9446 0.0 0
M  V30 18 C -0.2873 9.1957 0.0 0
M  V30 19 C -4.1668 6.9446 0.0 0
M  V30 20 C 2.263 7.7229 0.0 0
M  V30 21 C 0.9698 9.962 0.0 0
M  V30 22 C 2.227 9.2555 0.0 0
M  V30 23 C 3.4843 10.0338 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 10 11
M  V30 11 2 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 12 15
M  V30 15 2 13 16
M  V30 16 2 14 17
M  V30 17 1 14 18
M  V30 18 2 15 19
M  V30 19 1 17 20
M  V30 20 2 18 21
M  V30 21 2 20 22
M  V30 22 1 22 23
M  V30 23 1 7 8
M  V30 24 1 16 19
M  V30 25 1 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000114A1-20220106-C00013

>  <Row No>
109

$$$$
US20220000114A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 52 58 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -0.5019 -1.3673 0.0 0
M  V30 3 F -2.025 -1.6269 0.0 0
M  V30 4 C 0.4327 -2.4058 0.0 0
M  V30 5 N 0.0692 -3.8251 0.0 0
M  V30 6 C 1.8692 -2.1981 0.0 0
M  V30 7 N 1.3154 -4.5001 0.0 0
M  V30 8 C 2.5443 -0.8481 0.0 0
M  V30 9 C 2.4058 -3.5135 0.0 0
M  V30 10 C 1.4192 -5.9367 0.0 0
M  V30 11 O 1.7654 0.5019 0.0 0
M  V30 12 N 3.9982 -0.7961 0.0 0
M  V30 13 C 4.6732 0.5538 0.0 0
M  V30 14 C 6.1271 0.6057 0.0 0
M  V30 15 C 3.8943 1.9039 0.0 0
M  V30 16 C 6.8021 1.9558 0.0 0
M  V30 17 C 7.0271 -0.225 0.0 0
M  V30 18 C 4.5693 3.2539 0.0 0
M  V30 19 C 6.0232 3.3058 0.0 0
M  V30 20 C 7.7021 1.125 0.0 0
M  V30 21 C 9.208 1.125 0.0 0
M  V30 22 C 7.356 -1.6269 0.0 0
M  V30 23 C 8.031 -0.2769 0.0 0
M  V30 24 C 10.4542 0.45 0.0 0
M  V30 25 C 11.7869 1.0731 0.0 0
M  V30 26 C 10.2118 -0.9865 0.0 0
M  V30 27 F -0.4153 12.6004 0.0 0
M  V30 28 C -0.9173 11.233 0.0 0
M  V30 29 F -2.4404 10.9734 0.0 0
M  V30 30 C 0.0173 10.1945 0.0 0
M  V30 31 N -0.3461 8.7753 0.0 0
M  V30 32 C 1.4538 10.4022 0.0 0
M  V30 33 N 0.9 8.1002 0.0 0
M  V30 34 C 2.1289 11.7523 0.0 0
M  V30 35 C 1.9904 9.0868 0.0 0
M  V30 36 C 1.0038 6.6636 0.0 0
M  V30 37 O 1.35 13.1023 0.0 0
M  V30 38 N 3.5828 11.8042 0.0 0
M  V30 39 C 4.2578 13.1543 0.0 0
M  V30 40 C 5.7117 13.2062 0.0 0
M  V30 41 C 3.4789 14.5043 0.0 0
M  V30 42 C 6.3867 14.5562 0.0 0
M  V30 43 C 6.6117 12.3754 0.0 0
M  V30 44 C 4.1539 15.8544 0.0 0
M  V30 45 C 5.6078 15.9063 0.0 0
M  V30 46 C 7.2867 13.7254 0.0 0
M  V30 47 C 8.7926 13.7254 0.0 0
M  V30 48 C 6.9406 10.9734 0.0 0
M  V30 49 C 7.6156 12.3235 0.0 0
M  V30 50 C 9.1214 15.2313 0.0 0
M  V30 51 C 8.031 16.3217 0.0 0
M  V30 52 C 10.5234 15.664 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 2 16 19
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 1 17 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 24 25
M  V30 25 1 24 26
M  V30 26 1 27 28
M  V30 27 1 28 29
M  V30 28 1 28 30
M  V30 29 2 30 31
M  V30 30 1 30 32
M  V30 31 1 31 33
M  V30 32 1 32 34
M  V30 33 2 32 35
M  V30 34 1 33 36
M  V30 35 2 34 37
M  V30 36 1 34 38
M  V30 37 1 38 39
M  V30 38 2 39 40
M  V30 39 1 39 41
M  V30 40 1 40 42
M  V30 41 1 40 43
M  V30 42 2 41 44
M  V30 43 2 42 45
M  V30 44 1 42 46
M  V30 45 1 43 47
M  V30 46 1 43 48
M  V30 47 1 46 49
M  V30 48 1 47 50
M  V30 49 1 50 51
M  V30 50 1 50 52
M  V30 51 1 7 9
M  V30 52 1 18 19
M  V30 53 1 20 21
M  V30 54 1 22 23
M  V30 55 1 33 35
M  V30 56 1 44 45
M  V30 57 1 46 47
M  V30 58 1 48 49
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000114A1-20220106-C00014

>  <Row No>
110

$$$$
US20220000114A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -0.0356 1.5193 0.0 0
M  V30 3 C -1.3531 2.279 0.0 0
M  V30 4 C 1.2107 2.279 0.0 0
M  V30 5 F -2.6707 1.5549 0.0 0
M  V30 6 C -1.3887 3.7983 0.0 0
M  V30 7 C 1.1751 3.7983 0.0 0
M  V30 8 C 2.457 1.5549 0.0 0
M  V30 9 C -0.1424 4.5699 0.0 0
M  V30 10 C -0.178 6.0892 0.0 0
M  V30 11 C -1.4956 6.8489 0.0 0
M  V30 12 C 1.0682 6.8489 0.0 0
M  V30 13 N -2.8131 6.1367 0.0 0
M  V30 14 C -1.5312 8.3683 0.0 0
M  V30 15 C 1.0326 8.3683 0.0 0
M  V30 16 C -4.1307 6.8964 0.0 0
M  V30 17 C -0.2848 9.1398 0.0 0
M  V30 18 O -4.1663 8.4158 0.0 0
M  V30 19 C -5.4483 6.1842 0.0 0
M  V30 20 C -6.837 6.837 0.0 0
M  V30 21 C -5.6382 4.7479 0.0 0
M  V30 22 N -7.8579 5.7806 0.0 0
M  V30 23 C -7.1813 8.3208 0.0 0
M  V30 24 N -7.1219 4.4749 0.0 0
M  V30 25 F -6.1249 9.3416 0.0 0
M  V30 26 F -8.6294 8.8193 0.0 0
M  V30 27 C -7.7748 3.1574 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 2 6 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 16 19
M  V30 19 1 19 20
M  V30 20 2 19 21
M  V30 21 2 20 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 7 9
M  V30 28 1 15 17
M  V30 29 1 22 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00035001.cdx

>  <name>
US20220000114A1-20220106-C00015

>  <Row No>
111

$$$$
US20220000114A1-20220106-C00016
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 C -1.3904 0.648 0.0 0
M  V30 3 C 0.9544 1.1312 0.0 0
M  V30 4 C -1.2726 2.1563 0.0 0
M  V30 5 C -2.7101 -0.0707 0.0 0 CFG=2
M  V30 6 C 0.1885 2.4509 0.0 0
M  V30 7 N -2.4038 3.1815 0.0 0
M  V30 8 C -4.0299 0.6952 0.0 0
M  V30 9 C -2.7455 -1.52 0.0 0
M  V30 10 C -2.1328 4.6662 0.0 0
M  V30 11 C -5.3496 -0.0235 0.0 0
M  V30 12 O -0.7541 5.1611 0.0 0
M  V30 13 C -3.264 5.6914 0.0 0
M  V30 14 C -5.385 -1.4729 0.0 0
M  V30 15 C -6.6694 0.7423 0.0 0
M  V30 16 C -4.7487 5.4203 0.0 0
M  V30 17 C -3.1461 7.1996 0.0 0
M  V30 18 N -5.5146 6.7401 0.0 0
M  V30 19 C -5.3968 4.1006 0.0 0
M  V30 20 N -4.5366 7.8477 0.0 0
M  V30 21 F -4.5601 2.934 0.0 0
M  V30 22 F -6.905 3.9828 0.0 0
M  V30 23 F -6.0449 2.7808 0.0 0
M  V30 24 C -4.8783 9.3324 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 2 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9 CFG=1
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 2 10 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 11 15
M  V30 15 1 13 16
M  V30 16 2 13 17
M  V30 17 2 16 18
M  V30 18 1 16 19
M  V30 19 1 17 20
M  V30 20 1 19 21
M  V30 21 1 19 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 4 6
M  V30 25 1 18 20
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 5)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000114A1-20220106-C00016

>  <Row No>
112

$$$$
US20220000114A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.4361 -0.359 0.0 0
M  V30 3 Cl 2.4534 0.6981 0.0 0
M  V30 4 C 1.7553 -1.7553 0.0 0
M  V30 5 C 2.4335 -2.9521 0.0 0
M  V30 6 C 1.6955 -4.2686 0.0 0
M  V30 7 C 3.8298 -3.2713 0.0 0
M  V30 8 C 0.9175 -3.2713 0.0 0
M  V30 9 C 3.0917 -4.5878 0.0 0
M  V30 10 C 0.1795 -4.5878 0.0 0
M  V30 11 C 5.266 -3.2114 0.0 0
M  V30 12 C 3.7699 -5.8045 0.0 0
M  V30 13 C 5.9442 -4.4481 0.0 0
M  V30 14 C 6.2434 -2.1143 0.0 0
M  V30 15 C 5.2061 -5.7447 0.0 0
M  V30 16 C 7.6397 -2.4335 0.0 0
M  V30 17 O 7.9588 -3.8298 0.0 0
M  V30 18 C 8.6171 -1.3364 0.0 0
M  V30 19 C 10.0333 -1.496 0.0 0
M  V30 20 C 8.3378 0.1994 0.0 0
M  V30 21 N 10.6317 -0.0997 0.0 0
M  V30 22 C 10.6317 -2.7726 0.0 0
M  V30 23 N 9.6144 0.9175 0.0 0
M  V30 24 F 9.774 -3.9495 0.0 0
M  V30 25 C 12.0679 -2.7925 0.0 0
M  V30 26 C 9.774 2.4734 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 2 2 4
M  V30 4 1 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 9 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 14 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 18 19
M  V30 19 2 18 20
M  V30 20 2 19 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 2 7 9
M  V30 27 1 8 10
M  V30 28 1 13 15
M  V30 29 1 21 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000114A1-20220106-C00017

>  <Row No>
113

$$$$
US20220000114A1-20220106-C00018
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.461 0.0 0
M  V30 3 C -1.3652 -2.1915 0.0 0
M  V30 4 C 1.2215 -2.1915 0.0 0
M  V30 5 N -2.6945 -1.425 0.0 0
M  V30 6 C -1.4011 -3.6525 0.0 0
M  V30 7 C 1.1855 -3.6525 0.0 0
M  V30 8 C -4.0237 -2.1556 0.0 0
M  V30 9 C -2.7304 0.1077 0.0 0
M  V30 10 C -0.1437 -4.383 0.0 0
M  V30 11 C 2.443 -4.383 0.0 0
M  V30 12 N -5.353 -1.3891 0.0 0
M  V30 13 N -4.0597 -3.6166 0.0 0
M  V30 14 O -1.4729 0.8861 0.0 0
M  V30 15 C -4.0597 0.8861 0.0 0
M  V30 16 C -5.389 0.1437 0.0 0
M  V30 17 N -5.3051 -4.4549 0.0 0
M  V30 18 C -2.8861 -4.4549 0.0 0
M  V30 19 C -4.0956 2.419 0.0 0
M  V30 20 C -6.7182 0.9221 0.0 0
M  V30 21 C -4.874 -5.844 0.0 0
M  V30 22 N -3.389 -5.844 0.0 0
M  V30 23 C -5.4249 3.1974 0.0 0
M  V30 24 C -6.7542 2.4549 0.0 0
M  V30 25 F -5.4608 4.7303 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 8 13
M  V30 13 2 9 14
M  V30 14 1 9 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 1 15 19
M  V30 19 1 16 20
M  V30 20 2 17 21
M  V30 21 2 18 22
M  V30 22 2 19 23
M  V30 23 2 20 24
M  V30 24 1 23 25
M  V30 25 1 7 10
M  V30 26 2 15 16
M  V30 27 1 21 22
M  V30 28 1 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00038001.cdx

>  <name>
US20220000114A1-20220106-C00018

>  <Row No>
114

$$$$
US20220000114A1-20220106-C00019
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3365 -0.7089 0.0 0
M  V30 3 C -1.3714 -2.1734 0.0 0
M  V30 4 C -2.6731 0.0813 0.0 0
M  V30 5 C -2.708 -2.8823 0.0 0
M  V30 6 C -0.1046 -2.8823 0.0 0
M  V30 7 C -4.0097 -0.6276 0.0 0
M  V30 8 C -4.0446 -2.0804 0.0 0
M  V30 9 O 0.7554 -4.0678 0.0 0
M  V30 10 O 0.7554 -1.6271 0.0 0
M  V30 11 C -1.4411 -3.5797 0.0 0
M  V30 12 O -5.3463 0.1627 0.0 0
M  V30 13 C 2.1501 -3.5797 0.0 0
M  V30 14 C 2.1501 -2.0455 0.0 0
M  V30 15 N -1.476 -5.0441 0.0 0
M  V30 16 C -6.6829 -0.5462 0.0 0
M  V30 17 C 3.3356 -4.4398 0.0 0
M  V30 18 N -2.7312 -5.9042 0.0 0
M  V30 19 C -0.2905 -5.9042 0.0 0
M  V30 20 C -6.7178 -2.0106 0.0 0
M  V30 21 C -8.0195 0.244 0.0 0
M  V30 22 C -2.3128 -7.2989 0.0 0
M  V30 23 N -0.7787 -7.2989 0.0 0
M  V30 24 C -8.0544 -2.7196 0.0 0
M  V30 25 C -9.3561 -0.4649 0.0 0
M  V30 26 C -9.391 -1.9177 0.0 0
M  V30 27 Cl -10.7275 -2.6266 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 1 16 21
M  V30 21 2 18 22
M  V30 22 2 19 23
M  V30 23 1 20 24
M  V30 24 2 21 25
M  V30 25 2 24 26
M  V30 26 1 26 27
M  V30 27 1 7 8
M  V30 28 1 13 14
M  V30 29 1 22 23
M  V30 30 1 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00039001.cdx

>  <name>
US20220000114A1-20220106-C00019

>  <Row No>
115

$$$$
US20220000114A1-20220106-C00020
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.5973 -1.3532 0.0 0
M  V30 3 C 2.0725 -1.4751 0.0 0
M  V30 4 C -0.3291 -2.5479 0.0 0
M  V30 5 C 2.6698 -2.8283 0.0 0
M  V30 6 C 0.2682 -3.9011 0.0 0
M  V30 7 C 1.7433 -4.023 0.0 0
M  V30 8 N 2.3407 -5.3763 0.0 0
M  V30 9 N 3.7914 -5.6567 0.0 0
M  V30 10 C 1.5482 -6.6563 0.0 0
M  V30 11 C 3.9133 -7.1318 0.0 0
M  V30 12 C 2.5235 -7.7414 0.0 0
M  V30 13 O 5.1934 -7.8633 0.0 0
M  V30 14 C 6.4735 -7.083 0.0 0
M  V30 15 C 7.7536 -7.8145 0.0 0
M  V30 16 C 9.0336 -7.0221 0.0 0
M  V30 17 C 7.717 -9.3018 0.0 0
M  V30 18 N 8.9971 -5.4616 0.0 0
M  V30 19 C 10.3137 -7.7536 0.0 0
M  V30 20 C 8.9971 -10.0333 0.0 0
M  V30 21 O 10.2771 -4.6692 0.0 0
M  V30 22 C 7.6438 -4.6692 0.0 0
M  V30 23 C 10.2771 -9.2409 0.0 0
M  V30 24 C 11.5572 -5.4007 0.0 0
M  V30 25 O 6.2906 -5.4007 0.0 0
M  V30 26 O 7.6073 -3.1087 0.0 0
M  V30 27 C 6.254 -2.3163 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 8 10
M  V30 10 2 9 11
M  V30 11 2 10 12
M  V30 12 1 11 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 2 17 20
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 2 19 23
M  V30 23 1 21 24
M  V30 24 2 22 25
M  V30 25 1 22 26
M  V30 26 1 26 27
M  V30 27 1 6 7
M  V30 28 1 11 12
M  V30 29 1 20 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00040001.cdx

>  <name>
US20220000114A1-20220106-C00020

>  <Row No>
116

$$$$
US20220000114A1-20220106-C00021
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3344 -0.7333 0.0 0
M  V30 3 C -1.3705 -2.2001 0.0 0
M  V30 4 C -2.6689 0.036 0.0 0
M  V30 5 N -2.705 -2.9214 0.0 0
M  V30 6 C -0.1082 -2.9214 0.0 0
M  V30 7 C -4.0034 -0.6972 0.0 0
M  V30 8 C -4.0395 -2.1399 0.0 0
M  V30 9 C 1.1541 -2.1399 0.0 0
M  V30 10 C -5.3379 0.0841 0.0 0
M  V30 11 N 2.4165 -2.8613 0.0 0
M  V30 12 F -6.6724 -0.6371 0.0 0
M  V30 13 F -6.6724 0.8656 0.0 0
M  V30 14 F -5.374 1.623 0.0 0
M  V30 15 C 3.6788 -2.0798 0.0 0
M  V30 16 O 3.6427 -0.541 0.0 0
M  V30 17 C 4.9412 -2.8012 0.0 0
M  V30 18 C 6.2035 -2.0197 0.0 0
M  V30 19 C 4.9051 -4.2679 0.0 0
M  V30 20 C 7.4659 -2.7531 0.0 0
M  V30 21 C 6.1674 -0.4808 0.0 0
M  V30 22 C 6.1674 -5.0013 0.0 0
M  V30 23 C 7.4298 -4.2198 0.0 0
M  V30 24 F 4.833 0.2885 0.0 0
M  V30 25 F 6.1314 1.0579 0.0 0
M  V30 26 C 7.4298 0.2885 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 2 17 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 2 19 22
M  V30 22 2 20 23
M  V30 23 1 21 24
M  V30 24 1 21 25
M  V30 25 1 21 26
M  V30 26 1 7 8
M  V30 27 1 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00041001.cdx

>  <name>
US20220000114A1-20220106-C00021

>  <Row No>
117

$$$$
US20220000114A1-20220106-C00022
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -0.0361 -1.4681 0.0 0
M  V30 3 C -1.3718 -2.2021 0.0 0
M  V30 4 C 1.2274 -2.2021 0.0 0
M  V30 5 C -1.4079 -3.6703 0.0 0
M  V30 6 C -2.7076 -1.432 0.0 0 CFG=1
M  V30 7 C 1.1913 -3.6703 0.0 0
M  V30 8 C -0.1444 -4.4043 0.0 0
M  V30 9 O -1.444 -0.6498 0.0 0
M  V30 10 C -2.7437 0.1083 0.0 0
M  V30 11 C -4.0433 -2.166 0.0 0
M  V30 12 C -4.0794 0.8784 0.0 0
M  V30 13 C -1.4801 0.8784 0.0 0
M  V30 14 N -4.0794 -3.6342 0.0 0
M  V30 15 C -4.1155 2.4188 0.0 0
M  V30 16 C -1.5162 2.4188 0.0 0
M  V30 17 N -5.3309 -4.4765 0.0 0
M  V30 18 C -2.9001 -4.4765 0.0 0
M  V30 19 C -2.852 3.1889 0.0 0
M  V30 20 C -4.8977 -5.8725 0.0 0
M  V30 21 N -3.4055 -5.8725 0.0 0
M  V30 22 F -2.8881 4.7293 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9 CFG=1
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 2 10 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 2 13 16
M  V30 16 1 14 17
M  V30 17 1 14 18
M  V30 18 2 15 19
M  V30 19 2 17 20
M  V30 20 2 18 21
M  V30 21 1 19 22
M  V30 22 1 7 8
M  V30 23 1 16 19
M  V30 24 1 20 21
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 6)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00042001.cdx

>  <name>
US20220000114A1-20220106-C00022

>  <Row No>
118

$$$$
US20220000114A1-20220106-C00023
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0357 1.5244 0.0 0
M  V30 3 O -1.3577 2.2867 0.0 0
M  V30 4 C 1.2148 2.2867 0.0 0
M  V30 5 C -2.6797 1.5721 0.0 0
M  V30 6 N 2.4653 1.5721 0.0 0
M  V30 7 C 1.179 3.8111 0.0 0
M  V30 8 O 3.7158 2.3462 0.0 0
M  V30 9 C -0.1429 4.5853 0.0 0
M  V30 10 C 2.4296 4.5853 0.0 0
M  V30 11 C 4.9664 1.6316 0.0 0
M  V30 12 C -0.1786 6.1097 0.0 0
M  V30 13 C -1.4649 3.8588 0.0 0
M  V30 14 C 2.3938 6.1097 0.0 0
M  V30 15 C 1.0718 6.8839 0.0 0
M  V30 16 O -2.7869 4.6329 0.0 0
M  V30 17 C -4.1089 3.9064 0.0 0
M  V30 18 C -5.4309 4.6805 0.0 0
M  V30 19 C -4.1446 2.4534 0.0 0
M  V30 20 C -6.7529 3.966 0.0 0
M  V30 21 C -5.4666 6.205 0.0 0
M  V30 22 C -5.4666 1.7388 0.0 0
M  V30 23 C -6.7886 2.5129 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 12 15
M  V30 15 1 13 16
M  V30 16 1 16 17
M  V30 17 2 17 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 2 19 22
M  V30 22 2 20 23
M  V30 23 1 14 15
M  V30 24 1 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00043001.cdx

>  <name>
US20220000114A1-20220106-C00023

>  <Row No>
119

$$$$
US20220000114A1-20220106-C00024
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 14 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.2672 0.7724 0.0 0
M  V30 3 C 1.231 2.3172 0.0 0
M  V30 4 C 2.5345 0.0482 0.0 0
M  V30 5 Cl -0.1086 3.1017 0.0 0
M  V30 6 C 2.4982 3.1017 0.0 0
M  V30 7 Cl 2.4982 -1.4241 0.0 0
M  V30 8 C 3.8017 0.8327 0.0 0
M  V30 9 C 2.462 4.6465 0.0 0
M  V30 10 C 3.7655 2.3776 0.0 0
M  V30 11 C 5.069 0.1086 0.0 0
M  V30 12 N 2.4258 6.1914 0.0 0
M  V30 13 Cl 5.0328 3.162 0.0 0
M  V30 14 C 6.3362 -0.6155 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 1 8 11
M  V30 11 3 9 12
M  V30 12 1 10 13
M  V30 13 3 11 14
M  V30 14 1 8 10
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00044001.cdx

>  <name>
US20220000114A1-20220106-C00024

>  <Row No>
120

$$$$
US20220000114A1-20220106-C00025
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 9 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Mn 0.0 0.0 0.0 0 CHG=2
M  V30 2 S -2.8321 -1.2272 0.0 0
M  V30 3 C -2.8675 0.2832 0.0 0
M  V30 4 S -1.6285 1.0502 0.0 0 CHG=-1
M  V30 5 N -4.1774 1.0502 0.0 0
M  V30 6 C -5.4873 0.3422 0.0 0
M  V30 7 C -6.7972 1.1092 0.0 0
M  V30 8 N -8.1071 0.4012 0.0 0
M  V30 9 C -9.417 1.1682 0.0 0
M  V30 10 S -9.4524 2.6787 0.0 0
M  V30 11 NOT[S] -10.7269 0.4602 0.0 0
M  V30 12 C 2.0769 0.2832 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 2 3
M  V30 2 1 3 4
M  V30 3 1 3 5
M  V30 4 1 5 6
M  V30 5 1 6 7
M  V30 6 1 7 8
M  V30 7 1 8 9
M  V30 8 2 9 10
M  V30 9 1 9 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00045001.cdx

>  <name>
US20220000114A1-20220106-C00025

>  <Row No>
121

$$$$
US20220000114A1-20220106-C00026
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.7225 -1.2645 0.0 0
M  V30 3 O -0.7707 1.3367 0.0 0
M  V30 4 N -1.3367 -0.7225 0.0 0
M  V30 5 C 1.2645 0.7707 0.0 0
M  V30 6 C -1.3729 -2.1918 0.0 0
M  V30 7 C -2.6735 0.0481 0.0 0
M  V30 8 C 1.2284 2.3122 0.0 0
M  V30 9 C 2.529 0.0481 0.0 0
M  V30 10 O -0.1083 -2.9144 0.0 0
M  V30 11 N -2.7097 -2.9144 0.0 0
M  V30 12 C -4.0103 -0.6744 0.0 0
M  V30 13 C 2.4929 3.095 0.0 0
M  V30 14 C 3.7936 0.8309 0.0 0
M  V30 15 C -4.0465 -2.1316 0.0 0
M  V30 16 C -2.7458 -4.3837 0.0 0
M  V30 17 F -5.3471 0.0963 0.0 0
M  V30 18 C 3.7574 2.3604 0.0 0
M  V30 19 N -5.3833 -2.8542 0.0 0
M  V30 20 C 5.022 3.1432 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 6 11
M  V30 11 2 7 12
M  V30 12 1 8 13
M  V30 13 2 9 14
M  V30 14 1 11 15
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 18 20
M  V30 20 1 12 15
M  V30 21 1 14 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00048001.cdx

>  <name>
US20220000114A1-20220106-C00026

>  <Row No>
122

$$$$
US20220000114A1-20220106-C00027
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.7225 -1.2645 0.0 0
M  V30 3 O -0.7707 1.3367 0.0 0
M  V30 4 N -1.3367 -0.7225 0.0 0
M  V30 5 C 1.2645 0.7707 0.0 0
M  V30 6 C -1.3729 -2.1918 0.0 0
M  V30 7 C -2.6735 0.0481 0.0 0
M  V30 8 C 1.2284 2.3122 0.0 0
M  V30 9 C 2.529 0.0481 0.0 0
M  V30 10 O -0.1083 -2.9144 0.0 0
M  V30 11 N -2.7097 -2.9144 0.0 0
M  V30 12 C -4.0103 -0.6744 0.0 0
M  V30 13 C 2.4929 3.095 0.0 0
M  V30 14 C 3.7936 0.8309 0.0 0
M  V30 15 C -4.0465 -2.1316 0.0 0
M  V30 16 C -2.7458 -4.3837 0.0 0
M  V30 17 F -5.3471 0.0963 0.0 0
M  V30 18 C 3.7574 2.3604 0.0 0
M  V30 19 N -5.3833 -2.8542 0.0 0
M  V30 20 C 5.022 3.1432 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 6 11
M  V30 11 2 7 12
M  V30 12 1 8 13
M  V30 13 2 9 14
M  V30 14 1 11 15
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 18 20
M  V30 20 1 12 15
M  V30 21 1 14 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00049001.cdx

>  <name>
US20220000114A1-20220106-C00027

>  <Row No>
123

$$$$
US20220000117A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.876 -1.2075 0.0 0
M  V30 3 N 0.3788 -2.6281 0.0 0
M  V30 4 C 2.3677 -1.172 0.0 0
M  V30 5 S 1.5863 -3.5042 0.0 0
M  V30 6 Cl 3.2437 0.1065 0.0 0
M  V30 7 C 2.7939 -2.5926 0.0 0
M  V30 8 C 4.0843 -3.3029 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 7 8
M  V30 8 1 5 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000117A1-20220106-C00001

>  <Row No>
124

$$$$
US20220000117A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 7 5 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3134 -0.6977 0.0 0
M  V30 3 ? 1.2724 -0.7183 0.0 0
M  V30 4 ? -2.6269 0.0615 0.0 0
M  V30 5 N -0.2462 6.6494 0.0 0
M  V30 6 C -1.5597 7.4087 0.0 0
M  V30 7 ? -2.8732 8.1681 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 3 5 6
M  V30 5 1 6 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000117A1-20220106-C00002

>  <Row No>
125

$$$$
US20220000117A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000117A1-20220106-C00003

>  <Row No>
126

$$$$
US20220000117A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000117A1-20220106-C00004

>  <Row No>
127

$$$$
US20220000117A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=4
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000117A1-20220106-C00005

>  <Row No>
128

$$$$
US20220000117A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=6
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000117A1-20220106-C00006

>  <Row No>
129

$$$$
US20220000117A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=9
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000117A1-20220106-C00007

>  <Row No>
130

$$$$
US20220000117A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 110 113 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.6673 -1.232 0.0 0
M  V30 3 N 0.0 -2.618 0.0 0
M  V30 4 C 2.1047 -1.078 0.0 0
M  V30 5 S 1.1293 -3.388 0.0 0
M  V30 6 Cl 2.772 0.462 0.0 0
M  V30 7 C 2.464 -2.464 0.0 0
M  V30 8 C 3.6961 -3.1314 0.0 0
M  V30 9 N 4.9281 -3.7987 0.0 0
M  V30 10 Cl -1.232 -43.9425 0.0 0
M  V30 11 C -0.5646 -45.1745 0.0 0
M  V30 12 N -1.232 -46.5606 0.0 0
M  V30 13 C 0.8726 -45.0205 0.0 0
M  V30 14 S -0.1026 -47.3306 0.0 0
M  V30 15 Cl 1.54 -43.4805 0.0 0
M  V30 16 C 1.232 -46.4066 0.0 0
M  V30 17 C 2.464 -47.0739 0.0 0
M  V30 18 O 2.31 -48.5113 0.0 0
M  V30 19 O 3.6961 -46.0985 0.0 0
M  V30 20 C 3.542 -44.3532 0.0 0
M  V30 21 C 4.7741 -43.3778 0.0 0
M  V30 22 Cl -1.232 -36.1396 0.0 0
M  V30 23 C -0.5646 -37.3716 0.0 0
M  V30 24 N -1.232 -38.7577 0.0 0
M  V30 25 C 0.8726 -37.2176 0.0 0
M  V30 26 S -0.1026 -39.5277 0.0 0
M  V30 27 Cl 1.54 -35.6776 0.0 0
M  V30 28 C 1.232 -38.6037 0.0 0
M  V30 29 C 2.464 -39.271 0.0 0
M  V30 30 O 2.31 -40.7084 0.0 0
M  V30 31 O 3.6961 -38.2957 0.0 0
M  V30 32 C 3.542 -36.5503 0.0 0
M  V30 33 Cl -1.232 -27.926 0.0 0
M  V30 34 C -0.5646 -29.1581 0.0 0
M  V30 35 N -1.232 -30.5441 0.0 0
M  V30 36 C 0.8726 -29.0041 0.0 0
M  V30 37 S -0.1026 -31.3141 0.0 0
M  V30 38 Cl 1.54 -27.464 0.0 0
M  V30 39 C 1.232 -30.3901 0.0 0
M  V30 40 C 2.464 -31.0575 0.0 0
M  V30 41 O 2.31 -32.4948 0.0 0
M  V30 42 O 3.6961 -30.0821 0.0 0
M  V30 43 Cl -1.232 -51.7454 0.0 0
M  V30 44 C -0.5646 -52.9774 0.0 0
M  V30 45 N -1.232 -54.3634 0.0 0
M  V30 46 C 0.8726 -52.8234 0.0 0
M  V30 47 S -0.1026 -55.1335 0.0 0
M  V30 48 Cl 1.54 -51.2834 0.0 0
M  V30 49 C 1.232 -54.2094 0.0 0
M  V30 50 C 2.464 -54.8768 0.0 0
M  V30 51 O 2.31 -56.3142 0.0 0
M  V30 52 N 3.6961 -53.9014 0.0 0
M  V30 53 Cl -1.232 11.0883 0.0 0
M  V30 54 C -0.5646 9.8562 0.0 0
M  V30 55 N -1.232 8.4702 0.0 0
M  V30 56 C 0.8726 10.0102 0.0 0
M  V30 57 S -0.1026 7.7002 0.0 0
M  V30 58 Cl 1.54 11.5503 0.0 0
M  V30 59 C 1.232 8.6242 0.0 0
M  V30 60 C 2.464 7.9568 0.0 0
M  V30 61 O 3.6961 8.9322 0.0 0
M  V30 62 C 4.9281 8.2648 0.0 0
M  V30 63 N 4.7741 6.8275 0.0 0
M  V30 64 C 6.3141 8.9322 0.0 0
M  V30 65 S 6.1601 6.4681 0.0 0
M  V30 66 C 7.0841 7.8028 0.0 0
M  V30 67 C 6.8275 10.5749 0.0 0
M  V30 68 O 6.0061 5.0308 0.0 0
M  V30 69 O 7.3922 5.8008 0.0 0
M  V30 70 C 8.5215 8.1108 0.0 0
M  V30 71 C 8.2648 10.8829 0.0 0
M  V30 72 C 9.0349 9.7535 0.0 0
M  V30 73 Cl -1.232 -19.3018 0.0 0
M  V30 74 C -0.5646 -20.5338 0.0 0
M  V30 75 N -1.232 -21.9199 0.0 0
M  V30 76 C 0.8726 -20.3798 0.0 0
M  V30 77 S -0.1026 -22.6899 0.0 0
M  V30 78 Cl 1.54 -18.8398 0.0 0
M  V30 79 C 1.232 -21.7659 0.0 0
M  V30 80 C 2.464 -22.4332 0.0 0
M  V30 81 O 3.6961 -21.4579 0.0 0
M  V30 82 C 4.9281 -22.1252 0.0 0
M  V30 83 O 4.7741 -23.5626 0.0 0
M  V30 84 C 6.1601 -21.1499 0.0 0
M  V30 85 C 7.3922 -21.8172 0.0 0
M  V30 86 C 6.0061 -19.4045 0.0 0
M  V30 87 C 8.6242 -20.8419 0.0 0
M  V30 88 C 7.2381 -18.4291 0.0 0
M  V30 89 C 8.4702 -19.0965 0.0 0
M  V30 90 Cl -1.232 -11.4989 0.0 0
M  V30 91 C -0.5646 -12.731 0.0 0
M  V30 92 N -1.232 -14.117 0.0 0
M  V30 93 C 0.8726 -12.577 0.0 0
M  V30 94 S -0.1026 -14.887 0.0 0
M  V30 95 Cl 1.54 -11.0369 0.0 0
M  V30 96 C 1.232 -13.963 0.0 0
M  V30 97 C 2.464 -14.6303 0.0 0
M  V30 98 O 3.6961 -13.655 0.0 0
M  V30 99 C 4.9281 -14.3223 0.0 0
M  V30 100 O 4.7741 -15.7597 0.0 0
M  V30 101 C 6.1601 -13.347 0.0 0
M  V30 102 Cl -1.232 -5.3388 0.0 0
M  V30 103 C -0.5646 -6.5708 0.0 0
M  V30 104 N -1.232 -7.9568 0.0 0
M  V30 105 C 0.8726 -6.4168 0.0 0
M  V30 106 S -0.1026 -8.7269 0.0 0
M  V30 107 Cl 1.54 -4.8767 0.0 0
M  V30 108 C 1.232 -7.8028 0.0 0
M  V30 109 C 2.464 -8.4702 0.0 0
M  V30 110 O 3.6961 -7.4948 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 7 8
M  V30 8 3 8 9
M  V30 9 1 10 11
M  V30 10 2 11 12
M  V30 11 1 11 13
M  V30 12 1 12 14
M  V30 13 1 13 15
M  V30 14 2 13 16
M  V30 15 1 16 17
M  V30 16 2 17 18
M  V30 17 1 17 19
M  V30 18 1 19 20
M  V30 19 1 20 21
M  V30 20 1 22 23
M  V30 21 2 23 24
M  V30 22 1 23 25
M  V30 23 1 24 26
M  V30 24 1 25 27
M  V30 25 2 25 28
M  V30 26 1 28 29
M  V30 27 2 29 30
M  V30 28 1 29 31
M  V30 29 1 31 32
M  V30 30 1 33 34
M  V30 31 2 34 35
M  V30 32 1 34 36
M  V30 33 1 35 37
M  V30 34 1 36 38
M  V30 35 2 36 39
M  V30 36 1 39 40
M  V30 37 2 40 41
M  V30 38 1 40 42
M  V30 39 1 43 44
M  V30 40 2 44 45
M  V30 41 1 44 46
M  V30 42 1 45 47
M  V30 43 1 46 48
M  V30 44 2 46 49
M  V30 45 1 49 50
M  V30 46 2 50 51
M  V30 47 1 50 52
M  V30 48 1 53 54
M  V30 49 2 54 55
M  V30 50 1 54 56
M  V30 51 1 55 57
M  V30 52 1 56 58
M  V30 53 2 56 59
M  V30 54 1 59 60
M  V30 55 1 60 61
M  V30 56 1 61 62
M  V30 57 2 62 63
M  V30 58 1 62 64
M  V30 59 1 63 65
M  V30 60 2 64 66
M  V30 61 1 64 67
M  V30 62 2 65 68
M  V30 63 2 65 69
M  V30 64 1 66 70
M  V30 65 2 67 71
M  V30 66 2 70 72
M  V30 67 1 73 74
M  V30 68 2 74 75
M  V30 69 1 74 76
M  V30 70 1 75 77
M  V30 71 1 76 78
M  V30 72 2 76 79
M  V30 73 1 79 80
M  V30 74 1 80 81
M  V30 75 1 81 82
M  V30 76 2 82 83
M  V30 77 1 82 84
M  V30 78 2 84 85
M  V30 79 1 84 86
M  V30 80 1 85 87
M  V30 81 2 86 88
M  V30 82 2 87 89
M  V30 83 1 90 91
M  V30 84 2 91 92
M  V30 85 1 91 93
M  V30 86 1 92 94
M  V30 87 1 93 95
M  V30 88 2 93 96
M  V30 89 1 96 97
M  V30 90 1 97 98
M  V30 91 1 98 99
M  V30 92 2 99 100
M  V30 93 1 99 101
M  V30 94 1 102 103
M  V30 95 2 103 104
M  V30 96 1 103 105
M  V30 97 1 104 106
M  V30 98 1 105 107
M  V30 99 2 105 108
M  V30 100 1 108 109
M  V30 101 1 109 110
M  V30 102 1 5 7
M  V30 103 1 14 16
M  V30 104 1 26 28
M  V30 105 1 37 39
M  V30 106 1 47 49
M  V30 107 1 57 59
M  V30 108 1 65 66
M  V30 109 1 71 72
M  V30 110 1 77 79
M  V30 111 1 88 89
M  V30 112 1 94 96
M  V30 113 1 106 108
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000117A1-20220106-C00008

>  <Row No>
131

$$$$
US20220000117A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 106 108 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.6876 -1.2606 0.0 0
M  V30 3 N 0.0764 -2.6358 0.0 0
M  V30 4 C 2.1392 -1.146 0.0 0
M  V30 5 S 1.2224 -3.438 0.0 0
M  V30 6 Cl 2.8268 0.3438 0.0 0
M  V30 7 C 2.5212 -2.5212 0.0 0
M  V30 8 C 3.7818 -3.2088 0.0 0
M  V30 9 O 5.0424 -2.292 0.0 0
M  V30 10 N 3.6672 -4.6604 0.0 0
M  V30 11 C 6.303 -2.9796 0.0 0
M  V30 12 C 7.5637 -2.0628 0.0 0
M  V30 13 C 8.8243 -2.7504 0.0 0
M  V30 14 C 7.4491 -0.382 0.0 0
M  V30 15 C 10.0849 -1.8336 0.0 0
M  V30 16 C 8.7097 0.5348 0.0 0
M  V30 17 C 9.9703 -0.1528 0.0 0
M  V30 18 Cl -0.9168 8.5569 0.0 0
M  V30 19 C -0.2292 7.2963 0.0 0
M  V30 20 N -0.8404 5.921 0.0 0
M  V30 21 C 1.2224 7.4109 0.0 0
M  V30 22 S 0.3056 5.1188 0.0 0
M  V30 23 Cl 1.91 8.9007 0.0 0
M  V30 24 C 1.6044 6.0356 0.0 0
M  V30 25 C 2.865 5.348 0.0 0
M  V30 26 O 4.1256 6.2648 0.0 0
M  V30 27 N 2.7504 3.8964 0.0 0
M  V30 28 C 4.011 7.9457 0.0 0
M  V30 29 Cl -0.9168 -22.6147 0.0 0
M  V30 30 C -0.2292 -23.8753 0.0 0
M  V30 31 N -0.8404 -25.2505 0.0 0
M  V30 32 C 1.2224 -23.7607 0.0 0
M  V30 33 S 0.3056 -26.0527 0.0 0
M  V30 34 Cl 1.91 -22.2709 0.0 0
M  V30 35 C 1.6044 -25.1359 0.0 0
M  V30 36 C 2.865 -25.8235 0.0 0
M  V30 37 N 2.7504 -27.2751 0.0 0
M  V30 38 N 4.1256 -24.9067 0.0 0
M  V30 39 C 4.011 -23.2259 0.0 0
M  V30 40 C 5.2716 -22.3091 0.0 0
M  V30 41 Cl -0.9168 -38.5061 0.0 0
M  V30 42 C -0.2292 -39.7667 0.0 0
M  V30 43 N -0.8404 -41.1419 0.0 0
M  V30 44 C 1.2224 -39.6521 0.0 0
M  V30 45 S 0.3056 -41.9441 0.0 0
M  V30 46 Cl 1.91 -38.1623 0.0 0
M  V30 47 C 1.6044 -41.0273 0.0 0
M  V30 48 C 2.865 -41.7149 0.0 0
M  V30 49 N 4.1256 -40.7981 0.0 0
M  V30 50 N 2.7504 -43.1666 0.0 0
M  V30 51 C 5.3862 -41.4857 0.0 0
M  V30 52 Cl -0.9168 -6.4176 0.0 0
M  V30 53 C -0.2292 -7.6783 0.0 0
M  V30 54 N -0.8404 -9.0535 0.0 0
M  V30 55 C 1.2224 -7.5637 0.0 0
M  V30 56 S 0.3056 -9.8557 0.0 0
M  V30 57 Cl 1.91 -6.0738 0.0 0
M  V30 58 C 1.6044 -8.9389 0.0 0
M  V30 59 C 2.865 -9.6265 0.0 0
M  V30 60 N 2.7504 -11.0781 0.0 0
M  V30 61 N 4.1256 -8.7097 0.0 0
M  V30 62 Cl -0.9168 -14.3634 0.0 0
M  V30 63 C -0.2292 -15.624 0.0 0
M  V30 64 N -0.8404 -16.9992 0.0 0
M  V30 65 C 1.2224 -15.5094 0.0 0
M  V30 66 S 0.3056 -17.8014 0.0 0
M  V30 67 Cl 1.91 -14.0196 0.0 0
M  V30 68 C 1.6044 -16.8846 0.0 0
M  V30 69 C 2.865 -17.5722 0.0 0
M  V30 70 N 2.7504 -19.0238 0.0 0
M  V30 71 N 4.1256 -16.6554 0.0 0
M  V30 72 Cl -0.9168 16.8082 0.0 0
M  V30 73 C -0.2292 15.5476 0.0 0
M  V30 74 N -0.8404 14.1724 0.0 0
M  V30 75 C 1.2224 15.6622 0.0 0
M  V30 76 S 0.3056 13.3701 0.0 0
M  V30 77 Cl 1.91 17.152 0.0 0
M  V30 78 C 1.6044 14.287 0.0 0
M  V30 79 C 2.865 13.5993 0.0 0
M  V30 80 O 2.7504 12.1477 0.0 0
M  V30 81 C 4.1256 14.5162 0.0 0
M  V30 82 C 5.3862 13.8285 0.0 0
M  V30 83 C 6.6468 14.7454 0.0 0
M  V30 84 C 5.2716 12.3769 0.0 0
M  V30 85 C 6.5322 16.4262 0.0 0
M  V30 86 C 7.9075 14.0578 0.0 0
M  V30 87 C 6.5322 11.6893 0.0 0
M  V30 88 N 6.4176 18.107 0.0 0
M  V30 89 C 7.7929 12.6061 0.0 0
M  V30 90 Cl -0.9168 -30.2548 0.0 0
M  V30 91 C -0.2292 -31.5154 0.0 0
M  V30 92 N -0.8404 -32.8906 0.0 0
M  V30 93 C 1.2224 -31.4008 0.0 0
M  V30 94 S 0.3056 -33.6928 0.0 0
M  V30 95 Cl 1.91 -29.911 0.0 0
M  V30 96 C 1.6044 -32.776 0.0 0
M  V30 97 C 2.865 -33.4636 0.0 0
M  V30 98 N 2.7504 -34.9152 0.0 0
M  V30 99 C 4.1256 -32.5468 0.0 0
M  V30 100 C 5.3862 -33.2344 0.0 0
M  V30 101 C 5.2716 -34.686 0.0 0
M  V30 102 C 6.6468 -32.3176 0.0 0
M  V30 103 C 6.5322 -35.3737 0.0 0
M  V30 104 C 7.9075 -33.0052 0.0 0
M  V30 105 C 7.7929 -34.4568 0.0 0
M  V30 106 Cl 5.1952 -18.3362 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 2 8 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 2 15 17
M  V30 17 1 18 19
M  V30 18 2 19 20
M  V30 19 1 19 21
M  V30 20 1 20 22
M  V30 21 1 21 23
M  V30 22 2 21 24
M  V30 23 1 24 25
M  V30 24 1 25 26
M  V30 25 2 25 27
M  V30 26 1 26 28
M  V30 27 1 29 30
M  V30 28 2 30 31
M  V30 29 1 30 32
M  V30 30 1 31 33
M  V30 31 1 32 34
M  V30 32 2 32 35
M  V30 33 1 35 36
M  V30 34 2 36 37
M  V30 35 1 36 38
M  V30 36 1 38 39
M  V30 37 1 39 40
M  V30 38 1 41 42
M  V30 39 2 42 43
M  V30 40 1 42 44
M  V30 41 1 43 45
M  V30 42 1 44 46
M  V30 43 2 44 47
M  V30 44 1 47 48
M  V30 45 2 48 49
M  V30 46 1 48 50
M  V30 47 1 49 51
M  V30 48 1 52 53
M  V30 49 2 53 54
M  V30 50 1 53 55
M  V30 51 1 54 56
M  V30 52 1 55 57
M  V30 53 2 55 58
M  V30 54 1 58 59
M  V30 55 2 59 60
M  V30 56 1 59 61
M  V30 57 1 62 63
M  V30 58 2 63 64
M  V30 59 1 63 65
M  V30 60 1 64 66
M  V30 61 1 65 67
M  V30 62 2 65 68
M  V30 63 1 68 69
M  V30 64 2 69 70
M  V30 65 1 69 71
M  V30 66 1 72 73
M  V30 67 2 73 74
M  V30 68 1 73 75
M  V30 69 1 74 76
M  V30 70 1 75 77
M  V30 71 2 75 78
M  V30 72 1 78 79
M  V30 73 2 79 80
M  V30 74 1 79 81
M  V30 75 1 81 82
M  V30 76 2 82 83
M  V30 77 1 82 84
M  V30 78 1 83 85
M  V30 79 1 83 86
M  V30 80 2 84 87
M  V30 81 3 85 88
M  V30 82 2 86 89
M  V30 83 1 90 91
M  V30 84 2 91 92
M  V30 85 1 91 93
M  V30 86 1 92 94
M  V30 87 1 93 95
M  V30 88 2 93 96
M  V30 89 1 96 97
M  V30 90 2 97 98
M  V30 91 1 97 99
M  V30 92 1 99 100
M  V30 93 2 100 101
M  V30 94 1 100 102
M  V30 95 1 101 103
M  V30 96 2 102 104
M  V30 97 2 103 105
M  V30 98 1 5 7
M  V30 99 1 16 17
M  V30 100 1 22 24
M  V30 101 1 33 35
M  V30 102 1 45 47
M  V30 103 1 56 58
M  V30 104 1 66 68
M  V30 105 1 76 78
M  V30 106 1 87 89
M  V30 107 1 94 96
M  V30 108 1 104 105
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028002.cdx

>  <name>
US20220000117A1-20220106-C00009

>  <Row No>
132

$$$$
US20220000117A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 1.2552 -0.7172 0.0 0
M  V30 3 O -0.0358 -1.4584 0.0 0
M  V30 4 N -1.4584 0.502 0.0 0
M  V30 5 C 0.8368 1.2432 0.0 0
M  V30 6 C -1.4942 2.0322 0.0 0
M  V30 7 C -0.0717 2.4864 0.0 0
M  V30 8 C 2.2832 1.4345 0.0 0
M  V30 9 C 0.514 3.8851 0.0 0
M  V30 10 C 2.869 2.8331 0.0 0
M  V30 11 C 1.9605 4.0764 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 2 9 11
M  V30 11 1 6 7
M  V30 12 1 10 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000117A1-20220106-C00010

>  <Row No>
133

$$$$
US20220000117A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.6764 -1.3172 0.0 0
M  V30 3 N 0.178 -2.7413 0.0 0
M  V30 4 C 2.1717 -1.2816 0.0 0
M  V30 5 S 1.3884 -3.6195 0.0 0
M  V30 6 Cl 2.8837 0.083 0.0 0
M  V30 7 C 2.5989 -2.7057 0.0 0
M  V30 8 C 3.8924 -3.4177 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 7 8
M  V30 8 1 5 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000117A1-20220106-C00011

>  <Row No>
134

$$$$
US20220000117A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 7 5 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3134 -0.6977 0.0 0
M  V30 3 ? 1.2724 -0.7183 0.0 0
M  V30 4 ? -2.6269 0.0615 0.0 0
M  V30 5 N -0.2462 4.515 0.0 0
M  V30 6 C -1.5597 5.2743 0.0 0
M  V30 7 ? -2.8732 6.0337 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 3 5 6
M  V30 5 1 6 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000117A1-20220106-C00012

>  <Row No>
135

$$$$
US20220000117A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000117A1-20220106-C00013

>  <Row No>
136

$$$$
US20220000117A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000117A1-20220106-C00014

>  <Row No>
137

$$$$
US20220000117A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=4
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000117A1-20220106-C00015

>  <Row No>
138

$$$$
US20220000117A1-20220106-C00016
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=6
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00035001.cdx

>  <name>
US20220000117A1-20220106-C00016

>  <Row No>
139

$$$$
US20220000117A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=9
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000117A1-20220106-C00017

>  <Row No>
140

$$$$
US20220000117A1-20220106-C00018
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 110 113 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.6673 -1.232 0.0 0
M  V30 3 N 0.0 -2.618 0.0 0
M  V30 4 C 2.1047 -1.078 0.0 0
M  V30 5 S 1.1293 -3.388 0.0 0
M  V30 6 Cl 2.772 0.462 0.0 0
M  V30 7 C 2.464 -2.464 0.0 0
M  V30 8 C 3.6961 -3.1314 0.0 0
M  V30 9 N 4.9281 -3.7987 0.0 0
M  V30 10 Cl -1.232 -43.9425 0.0 0
M  V30 11 C -0.5646 -45.1745 0.0 0
M  V30 12 N -1.232 -46.5606 0.0 0
M  V30 13 C 0.8726 -45.0205 0.0 0
M  V30 14 S -0.1026 -47.3306 0.0 0
M  V30 15 Cl 1.54 -43.4805 0.0 0
M  V30 16 C 1.232 -46.4066 0.0 0
M  V30 17 C 2.464 -47.0739 0.0 0
M  V30 18 O 2.31 -48.5113 0.0 0
M  V30 19 O 3.6961 -46.0985 0.0 0
M  V30 20 C 3.542 -44.3532 0.0 0
M  V30 21 C 4.7741 -43.3778 0.0 0
M  V30 22 Cl -1.232 -36.1396 0.0 0
M  V30 23 C -0.5646 -37.3716 0.0 0
M  V30 24 N -1.232 -38.7577 0.0 0
M  V30 25 C 0.8726 -37.2176 0.0 0
M  V30 26 S -0.1026 -39.5277 0.0 0
M  V30 27 Cl 1.54 -35.6776 0.0 0
M  V30 28 C 1.232 -38.6037 0.0 0
M  V30 29 C 2.464 -39.271 0.0 0
M  V30 30 O 2.31 -40.7084 0.0 0
M  V30 31 O 3.6961 -38.2957 0.0 0
M  V30 32 C 3.542 -36.5503 0.0 0
M  V30 33 Cl -1.232 -27.926 0.0 0
M  V30 34 C -0.5646 -29.1581 0.0 0
M  V30 35 N -1.232 -30.5441 0.0 0
M  V30 36 C 0.8726 -29.0041 0.0 0
M  V30 37 S -0.1026 -31.3141 0.0 0
M  V30 38 Cl 1.54 -27.464 0.0 0
M  V30 39 C 1.232 -30.3901 0.0 0
M  V30 40 C 2.464 -31.0575 0.0 0
M  V30 41 O 2.31 -32.4948 0.0 0
M  V30 42 O 3.6961 -30.0821 0.0 0
M  V30 43 Cl -1.232 -51.7454 0.0 0
M  V30 44 C -0.5646 -52.9774 0.0 0
M  V30 45 N -1.232 -54.3634 0.0 0
M  V30 46 C 0.8726 -52.8234 0.0 0
M  V30 47 S -0.1026 -55.1335 0.0 0
M  V30 48 Cl 1.54 -51.2834 0.0 0
M  V30 49 C 1.232 -54.2094 0.0 0
M  V30 50 C 2.464 -54.8768 0.0 0
M  V30 51 O 2.31 -56.3142 0.0 0
M  V30 52 N 3.6961 -53.9014 0.0 0
M  V30 53 Cl -1.232 11.0883 0.0 0
M  V30 54 C -0.5646 9.8562 0.0 0
M  V30 55 N -1.232 8.4702 0.0 0
M  V30 56 C 0.8726 10.0102 0.0 0
M  V30 57 S -0.1026 7.7002 0.0 0
M  V30 58 Cl 1.54 11.5503 0.0 0
M  V30 59 C 1.232 8.6242 0.0 0
M  V30 60 C 2.464 7.9568 0.0 0
M  V30 61 O 3.6961 8.9322 0.0 0
M  V30 62 C 4.9281 8.2648 0.0 0
M  V30 63 N 4.7741 6.8275 0.0 0
M  V30 64 C 6.3141 8.9322 0.0 0
M  V30 65 S 6.1601 6.4681 0.0 0
M  V30 66 C 7.0841 7.8028 0.0 0
M  V30 67 C 6.8275 10.5749 0.0 0
M  V30 68 O 6.0061 5.0308 0.0 0
M  V30 69 O 7.3922 5.8008 0.0 0
M  V30 70 C 8.5215 8.1108 0.0 0
M  V30 71 C 8.2648 10.8829 0.0 0
M  V30 72 C 9.0349 9.7535 0.0 0
M  V30 73 Cl -1.232 -19.3018 0.0 0
M  V30 74 C -0.5646 -20.5338 0.0 0
M  V30 75 N -1.232 -21.9199 0.0 0
M  V30 76 C 0.8726 -20.3798 0.0 0
M  V30 77 S -0.1026 -22.6899 0.0 0
M  V30 78 Cl 1.54 -18.8398 0.0 0
M  V30 79 C 1.232 -21.7659 0.0 0
M  V30 80 C 2.464 -22.4332 0.0 0
M  V30 81 O 3.6961 -21.4579 0.0 0
M  V30 82 C 4.9281 -22.1252 0.0 0
M  V30 83 O 4.7741 -23.5626 0.0 0
M  V30 84 C 6.1601 -21.1499 0.0 0
M  V30 85 C 7.3922 -21.8172 0.0 0
M  V30 86 C 6.0061 -19.4045 0.0 0
M  V30 87 C 8.6242 -20.8419 0.0 0
M  V30 88 C 7.2381 -18.4291 0.0 0
M  V30 89 C 8.4702 -19.0965 0.0 0
M  V30 90 Cl -1.232 -11.4989 0.0 0
M  V30 91 C -0.5646 -12.731 0.0 0
M  V30 92 N -1.232 -14.117 0.0 0
M  V30 93 C 0.8726 -12.577 0.0 0
M  V30 94 S -0.1026 -14.887 0.0 0
M  V30 95 Cl 1.54 -11.0369 0.0 0
M  V30 96 C 1.232 -13.963 0.0 0
M  V30 97 C 2.464 -14.6303 0.0 0
M  V30 98 O 3.6961 -13.655 0.0 0
M  V30 99 C 4.9281 -14.3223 0.0 0
M  V30 100 O 4.7741 -15.7597 0.0 0
M  V30 101 C 6.1601 -13.347 0.0 0
M  V30 102 Cl -1.232 -5.3388 0.0 0
M  V30 103 C -0.5646 -6.5708 0.0 0
M  V30 104 N -1.232 -7.9568 0.0 0
M  V30 105 C 0.8726 -6.4168 0.0 0
M  V30 106 S -0.1026 -8.7269 0.0 0
M  V30 107 Cl 1.54 -4.8767 0.0 0
M  V30 108 C 1.232 -7.8028 0.0 0
M  V30 109 C 2.464 -8.4702 0.0 0
M  V30 110 O 3.6961 -7.4948 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 7 8
M  V30 8 3 8 9
M  V30 9 1 10 11
M  V30 10 2 11 12
M  V30 11 1 11 13
M  V30 12 1 12 14
M  V30 13 1 13 15
M  V30 14 2 13 16
M  V30 15 1 16 17
M  V30 16 2 17 18
M  V30 17 1 17 19
M  V30 18 1 19 20
M  V30 19 1 20 21
M  V30 20 1 22 23
M  V30 21 2 23 24
M  V30 22 1 23 25
M  V30 23 1 24 26
M  V30 24 1 25 27
M  V30 25 2 25 28
M  V30 26 1 28 29
M  V30 27 2 29 30
M  V30 28 1 29 31
M  V30 29 1 31 32
M  V30 30 1 33 34
M  V30 31 2 34 35
M  V30 32 1 34 36
M  V30 33 1 35 37
M  V30 34 1 36 38
M  V30 35 2 36 39
M  V30 36 1 39 40
M  V30 37 2 40 41
M  V30 38 1 40 42
M  V30 39 1 43 44
M  V30 40 2 44 45
M  V30 41 1 44 46
M  V30 42 1 45 47
M  V30 43 1 46 48
M  V30 44 2 46 49
M  V30 45 1 49 50
M  V30 46 2 50 51
M  V30 47 1 50 52
M  V30 48 1 53 54
M  V30 49 2 54 55
M  V30 50 1 54 56
M  V30 51 1 55 57
M  V30 52 1 56 58
M  V30 53 2 56 59
M  V30 54 1 59 60
M  V30 55 1 60 61
M  V30 56 1 61 62
M  V30 57 2 62 63
M  V30 58 1 62 64
M  V30 59 1 63 65
M  V30 60 2 64 66
M  V30 61 1 64 67
M  V30 62 2 65 68
M  V30 63 2 65 69
M  V30 64 1 66 70
M  V30 65 2 67 71
M  V30 66 2 70 72
M  V30 67 1 73 74
M  V30 68 2 74 75
M  V30 69 1 74 76
M  V30 70 1 75 77
M  V30 71 1 76 78
M  V30 72 2 76 79
M  V30 73 1 79 80
M  V30 74 1 80 81
M  V30 75 1 81 82
M  V30 76 2 82 83
M  V30 77 1 82 84
M  V30 78 2 84 85
M  V30 79 1 84 86
M  V30 80 1 85 87
M  V30 81 2 86 88
M  V30 82 2 87 89
M  V30 83 1 90 91
M  V30 84 2 91 92
M  V30 85 1 91 93
M  V30 86 1 92 94
M  V30 87 1 93 95
M  V30 88 2 93 96
M  V30 89 1 96 97
M  V30 90 1 97 98
M  V30 91 1 98 99
M  V30 92 2 99 100
M  V30 93 1 99 101
M  V30 94 1 102 103
M  V30 95 2 103 104
M  V30 96 1 103 105
M  V30 97 1 104 106
M  V30 98 1 105 107
M  V30 99 2 105 108
M  V30 100 1 108 109
M  V30 101 1 109 110
M  V30 102 1 5 7
M  V30 103 1 14 16
M  V30 104 1 26 28
M  V30 105 1 37 39
M  V30 106 1 47 49
M  V30 107 1 57 59
M  V30 108 1 65 66
M  V30 109 1 71 72
M  V30 110 1 77 79
M  V30 111 1 88 89
M  V30 112 1 94 96
M  V30 113 1 106 108
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000117A1-20220106-C00018

>  <Row No>
141

$$$$
US20220000117A1-20220106-C00019
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 106 108 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.6876 -1.2606 0.0 0
M  V30 3 N 0.0764 -2.6358 0.0 0
M  V30 4 C 2.1392 -1.146 0.0 0
M  V30 5 S 1.2224 -3.438 0.0 0
M  V30 6 Cl 2.8268 0.3438 0.0 0
M  V30 7 C 2.5212 -2.5212 0.0 0
M  V30 8 C 3.7818 -3.2088 0.0 0
M  V30 9 O 5.0424 -2.292 0.0 0
M  V30 10 N 3.6672 -4.6604 0.0 0
M  V30 11 C 6.303 -2.9796 0.0 0
M  V30 12 C 7.5637 -2.0628 0.0 0
M  V30 13 C 8.8243 -2.7504 0.0 0
M  V30 14 C 7.4491 -0.382 0.0 0
M  V30 15 C 10.0849 -1.8336 0.0 0
M  V30 16 C 8.7097 0.5348 0.0 0
M  V30 17 C 9.9703 -0.1528 0.0 0
M  V30 18 Cl -0.9168 8.5569 0.0 0
M  V30 19 C -0.2292 7.2963 0.0 0
M  V30 20 N -0.8404 5.921 0.0 0
M  V30 21 C 1.2224 7.4109 0.0 0
M  V30 22 S 0.3056 5.1188 0.0 0
M  V30 23 Cl 1.91 8.9007 0.0 0
M  V30 24 C 1.6044 6.0356 0.0 0
M  V30 25 C 2.865 5.348 0.0 0
M  V30 26 O 4.1256 6.2648 0.0 0
M  V30 27 N 2.7504 3.8964 0.0 0
M  V30 28 C 4.011 7.9457 0.0 0
M  V30 29 Cl -0.9168 -22.6147 0.0 0
M  V30 30 C -0.2292 -23.8753 0.0 0
M  V30 31 N -0.8404 -25.2505 0.0 0
M  V30 32 C 1.2224 -23.7607 0.0 0
M  V30 33 S 0.3056 -26.0527 0.0 0
M  V30 34 Cl 1.91 -22.2709 0.0 0
M  V30 35 C 1.6044 -25.1359 0.0 0
M  V30 36 C 2.865 -25.8235 0.0 0
M  V30 37 N 2.7504 -27.2751 0.0 0
M  V30 38 N 4.1256 -24.9067 0.0 0
M  V30 39 C 4.011 -23.2259 0.0 0
M  V30 40 C 5.2716 -22.3091 0.0 0
M  V30 41 Cl -0.9168 -38.5061 0.0 0
M  V30 42 C -0.2292 -39.7667 0.0 0
M  V30 43 N -0.8404 -41.1419 0.0 0
M  V30 44 C 1.2224 -39.6521 0.0 0
M  V30 45 S 0.3056 -41.9441 0.0 0
M  V30 46 Cl 1.91 -38.1623 0.0 0
M  V30 47 C 1.6044 -41.0273 0.0 0
M  V30 48 C 2.865 -41.7149 0.0 0
M  V30 49 N 4.1256 -40.7981 0.0 0
M  V30 50 N 2.7504 -43.1666 0.0 0
M  V30 51 C 5.3862 -41.4857 0.0 0
M  V30 52 Cl -0.9168 -6.4176 0.0 0
M  V30 53 C -0.2292 -7.6783 0.0 0
M  V30 54 N -0.8404 -9.0535 0.0 0
M  V30 55 C 1.2224 -7.5637 0.0 0
M  V30 56 S 0.3056 -9.8557 0.0 0
M  V30 57 Cl 1.91 -6.0738 0.0 0
M  V30 58 C 1.6044 -8.9389 0.0 0
M  V30 59 C 2.865 -9.6265 0.0 0
M  V30 60 N 2.7504 -11.0781 0.0 0
M  V30 61 N 4.1256 -8.7097 0.0 0
M  V30 62 Cl -0.9168 -14.3634 0.0 0
M  V30 63 C -0.2292 -15.624 0.0 0
M  V30 64 N -0.8404 -16.9992 0.0 0
M  V30 65 C 1.2224 -15.5094 0.0 0
M  V30 66 S 0.3056 -17.8014 0.0 0
M  V30 67 Cl 1.91 -14.0196 0.0 0
M  V30 68 C 1.6044 -16.8846 0.0 0
M  V30 69 C 2.865 -17.5722 0.0 0
M  V30 70 N 2.7504 -19.0238 0.0 0
M  V30 71 N 4.1256 -16.6554 0.0 0
M  V30 72 Cl -0.9168 16.8082 0.0 0
M  V30 73 C -0.2292 15.5476 0.0 0
M  V30 74 N -0.8404 14.1724 0.0 0
M  V30 75 C 1.2224 15.6622 0.0 0
M  V30 76 S 0.3056 13.3701 0.0 0
M  V30 77 Cl 1.91 17.152 0.0 0
M  V30 78 C 1.6044 14.287 0.0 0
M  V30 79 C 2.865 13.5993 0.0 0
M  V30 80 O 2.7504 12.1477 0.0 0
M  V30 81 C 4.1256 14.5162 0.0 0
M  V30 82 C 5.3862 13.8285 0.0 0
M  V30 83 C 6.6468 14.7454 0.0 0
M  V30 84 C 5.2716 12.3769 0.0 0
M  V30 85 C 6.5322 16.4262 0.0 0
M  V30 86 C 7.9075 14.0578 0.0 0
M  V30 87 C 6.5322 11.6893 0.0 0
M  V30 88 N 6.4176 18.107 0.0 0
M  V30 89 C 7.7929 12.6061 0.0 0
M  V30 90 Cl -0.9168 -30.2548 0.0 0
M  V30 91 C -0.2292 -31.5154 0.0 0
M  V30 92 N -0.8404 -32.8906 0.0 0
M  V30 93 C 1.2224 -31.4008 0.0 0
M  V30 94 S 0.3056 -33.6928 0.0 0
M  V30 95 Cl 1.91 -29.911 0.0 0
M  V30 96 C 1.6044 -32.776 0.0 0
M  V30 97 C 2.865 -33.4636 0.0 0
M  V30 98 N 2.7504 -34.9152 0.0 0
M  V30 99 C 4.1256 -32.5468 0.0 0
M  V30 100 C 5.3862 -33.2344 0.0 0
M  V30 101 C 5.2716 -34.686 0.0 0
M  V30 102 C 6.6468 -32.3176 0.0 0
M  V30 103 C 6.5322 -35.3737 0.0 0
M  V30 104 C 7.9075 -33.0052 0.0 0
M  V30 105 C 7.7929 -34.4568 0.0 0
M  V30 106 Cl 5.1952 -18.3362 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 2 8 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 2 15 17
M  V30 17 1 18 19
M  V30 18 2 19 20
M  V30 19 1 19 21
M  V30 20 1 20 22
M  V30 21 1 21 23
M  V30 22 2 21 24
M  V30 23 1 24 25
M  V30 24 1 25 26
M  V30 25 2 25 27
M  V30 26 1 26 28
M  V30 27 1 29 30
M  V30 28 2 30 31
M  V30 29 1 30 32
M  V30 30 1 31 33
M  V30 31 1 32 34
M  V30 32 2 32 35
M  V30 33 1 35 36
M  V30 34 2 36 37
M  V30 35 1 36 38
M  V30 36 1 38 39
M  V30 37 1 39 40
M  V30 38 1 41 42
M  V30 39 2 42 43
M  V30 40 1 42 44
M  V30 41 1 43 45
M  V30 42 1 44 46
M  V30 43 2 44 47
M  V30 44 1 47 48
M  V30 45 2 48 49
M  V30 46 1 48 50
M  V30 47 1 49 51
M  V30 48 1 52 53
M  V30 49 2 53 54
M  V30 50 1 53 55
M  V30 51 1 54 56
M  V30 52 1 55 57
M  V30 53 2 55 58
M  V30 54 1 58 59
M  V30 55 2 59 60
M  V30 56 1 59 61
M  V30 57 1 62 63
M  V30 58 2 63 64
M  V30 59 1 63 65
M  V30 60 1 64 66
M  V30 61 1 65 67
M  V30 62 2 65 68
M  V30 63 1 68 69
M  V30 64 2 69 70
M  V30 65 1 69 71
M  V30 66 1 72 73
M  V30 67 2 73 74
M  V30 68 1 73 75
M  V30 69 1 74 76
M  V30 70 1 75 77
M  V30 71 2 75 78
M  V30 72 1 78 79
M  V30 73 2 79 80
M  V30 74 1 79 81
M  V30 75 1 81 82
M  V30 76 2 82 83
M  V30 77 1 82 84
M  V30 78 1 83 85
M  V30 79 1 83 86
M  V30 80 2 84 87
M  V30 81 3 85 88
M  V30 82 2 86 89
M  V30 83 1 90 91
M  V30 84 2 91 92
M  V30 85 1 91 93
M  V30 86 1 92 94
M  V30 87 1 93 95
M  V30 88 2 93 96
M  V30 89 1 96 97
M  V30 90 2 97 98
M  V30 91 1 97 99
M  V30 92 1 99 100
M  V30 93 2 100 101
M  V30 94 1 100 102
M  V30 95 1 101 103
M  V30 96 2 102 104
M  V30 97 2 103 105
M  V30 98 1 5 7
M  V30 99 1 16 17
M  V30 100 1 22 24
M  V30 101 1 33 35
M  V30 102 1 45 47
M  V30 103 1 56 58
M  V30 104 1 66 68
M  V30 105 1 76 78
M  V30 106 1 87 89
M  V30 107 1 94 96
M  V30 108 1 104 105
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00037002.cdx

>  <name>
US20220000117A1-20220106-C00019

>  <Row No>
142

$$$$
US20220000117A1-20220106-C00020
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.6764 -1.3172 0.0 0
M  V30 3 N 0.178 -2.7413 0.0 0
M  V30 4 C 2.1717 -1.2816 0.0 0
M  V30 5 S 1.3884 -3.6195 0.0 0
M  V30 6 Cl 2.8837 0.083 0.0 0
M  V30 7 C 2.5989 -2.7057 0.0 0
M  V30 8 C 3.8924 -3.4177 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 7 8
M  V30 8 1 5 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00057001.cdx

>  <name>
US20220000117A1-20220106-C00020

>  <Row No>
143

$$$$
US20220000117A1-20220106-C00021
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 7 5 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3134 -0.6977 0.0 0
M  V30 3 ? 1.2724 -0.7183 0.0 0
M  V30 4 ? -2.6269 0.0615 0.0 0
M  V30 5 N -0.2462 4.515 0.0 0
M  V30 6 C -1.5597 5.2743 0.0 0
M  V30 7 ? -2.8732 6.0337 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 3 5 6
M  V30 5 1 6 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00058001.cdx

>  <name>
US20220000117A1-20220106-C00021

>  <Row No>
144

$$$$
US20220000117A1-20220106-C00022
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00059001.cdx

>  <name>
US20220000117A1-20220106-C00022

>  <Row No>
145

$$$$
US20220000117A1-20220106-C00023
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00060001.cdx

>  <name>
US20220000117A1-20220106-C00023

>  <Row No>
146

$$$$
US20220000117A1-20220106-C00024
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=4
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00061001.cdx

>  <name>
US20220000117A1-20220106-C00024

>  <Row No>
147

$$$$
US20220000117A1-20220106-C00025
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=6
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00062001.cdx

>  <name>
US20220000117A1-20220106-C00025

>  <Row No>
148

$$$$
US20220000117A1-20220106-C00026
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=9
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00063001.cdx

>  <name>
US20220000117A1-20220106-C00026

>  <Row No>
149

$$$$
US20220000117A1-20220106-C00027
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 110 113 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.6673 -1.232 0.0 0
M  V30 3 N 0.0 -2.618 0.0 0
M  V30 4 C 2.1047 -1.078 0.0 0
M  V30 5 S 1.1293 -3.388 0.0 0
M  V30 6 Cl 2.772 0.462 0.0 0
M  V30 7 C 2.464 -2.464 0.0 0
M  V30 8 C 3.6961 -3.1314 0.0 0
M  V30 9 N 4.9281 -3.7987 0.0 0
M  V30 10 Cl -1.232 -43.9425 0.0 0
M  V30 11 C -0.5646 -45.1745 0.0 0
M  V30 12 N -1.232 -46.5606 0.0 0
M  V30 13 C 0.8726 -45.0205 0.0 0
M  V30 14 S -0.1026 -47.3306 0.0 0
M  V30 15 Cl 1.54 -43.4805 0.0 0
M  V30 16 C 1.232 -46.4066 0.0 0
M  V30 17 C 2.464 -47.0739 0.0 0
M  V30 18 O 2.31 -48.5113 0.0 0
M  V30 19 O 3.6961 -46.0985 0.0 0
M  V30 20 C 3.542 -44.3532 0.0 0
M  V30 21 C 4.7741 -43.3778 0.0 0
M  V30 22 Cl -1.232 -36.1396 0.0 0
M  V30 23 C -0.5646 -37.3716 0.0 0
M  V30 24 N -1.232 -38.7577 0.0 0
M  V30 25 C 0.8726 -37.2176 0.0 0
M  V30 26 S -0.1026 -39.5277 0.0 0
M  V30 27 Cl 1.54 -35.6776 0.0 0
M  V30 28 C 1.232 -38.6037 0.0 0
M  V30 29 C 2.464 -39.271 0.0 0
M  V30 30 O 2.31 -40.7084 0.0 0
M  V30 31 O 3.6961 -38.2957 0.0 0
M  V30 32 C 3.542 -36.5503 0.0 0
M  V30 33 Cl -1.232 -27.926 0.0 0
M  V30 34 C -0.5646 -29.1581 0.0 0
M  V30 35 N -1.232 -30.5441 0.0 0
M  V30 36 C 0.8726 -29.0041 0.0 0
M  V30 37 S -0.1026 -31.3141 0.0 0
M  V30 38 Cl 1.54 -27.464 0.0 0
M  V30 39 C 1.232 -30.3901 0.0 0
M  V30 40 C 2.464 -31.0575 0.0 0
M  V30 41 O 2.31 -32.4948 0.0 0
M  V30 42 O 3.6961 -30.0821 0.0 0
M  V30 43 Cl -1.232 -51.7454 0.0 0
M  V30 44 C -0.5646 -52.9774 0.0 0
M  V30 45 N -1.232 -54.3634 0.0 0
M  V30 46 C 0.8726 -52.8234 0.0 0
M  V30 47 S -0.1026 -55.1335 0.0 0
M  V30 48 Cl 1.54 -51.2834 0.0 0
M  V30 49 C 1.232 -54.2094 0.0 0
M  V30 50 C 2.464 -54.8768 0.0 0
M  V30 51 O 2.31 -56.3142 0.0 0
M  V30 52 N 3.6961 -53.9014 0.0 0
M  V30 53 Cl -1.232 11.0883 0.0 0
M  V30 54 C -0.5646 9.8562 0.0 0
M  V30 55 N -1.232 8.4702 0.0 0
M  V30 56 C 0.8726 10.0102 0.0 0
M  V30 57 S -0.1026 7.7002 0.0 0
M  V30 58 Cl 1.54 11.5503 0.0 0
M  V30 59 C 1.232 8.6242 0.0 0
M  V30 60 C 2.464 7.9568 0.0 0
M  V30 61 O 3.6961 8.9322 0.0 0
M  V30 62 C 4.9281 8.2648 0.0 0
M  V30 63 N 4.7741 6.8275 0.0 0
M  V30 64 C 6.3141 8.9322 0.0 0
M  V30 65 S 6.1601 6.4681 0.0 0
M  V30 66 C 7.0841 7.8028 0.0 0
M  V30 67 C 6.8275 10.5749 0.0 0
M  V30 68 O 6.0061 5.0308 0.0 0
M  V30 69 O 7.3922 5.8008 0.0 0
M  V30 70 C 8.5215 8.1108 0.0 0
M  V30 71 C 8.2648 10.8829 0.0 0
M  V30 72 C 9.0349 9.7535 0.0 0
M  V30 73 Cl -1.232 -19.3018 0.0 0
M  V30 74 C -0.5646 -20.5338 0.0 0
M  V30 75 N -1.232 -21.9199 0.0 0
M  V30 76 C 0.8726 -20.3798 0.0 0
M  V30 77 S -0.1026 -22.6899 0.0 0
M  V30 78 Cl 1.54 -18.8398 0.0 0
M  V30 79 C 1.232 -21.7659 0.0 0
M  V30 80 C 2.464 -22.4332 0.0 0
M  V30 81 O 3.6961 -21.4579 0.0 0
M  V30 82 C 4.9281 -22.1252 0.0 0
M  V30 83 O 4.7741 -23.5626 0.0 0
M  V30 84 C 6.1601 -21.1499 0.0 0
M  V30 85 C 7.3922 -21.8172 0.0 0
M  V30 86 C 6.0061 -19.4045 0.0 0
M  V30 87 C 8.6242 -20.8419 0.0 0
M  V30 88 C 7.2381 -18.4291 0.0 0
M  V30 89 C 8.4702 -19.0965 0.0 0
M  V30 90 Cl -1.232 -11.4989 0.0 0
M  V30 91 C -0.5646 -12.731 0.0 0
M  V30 92 N -1.232 -14.117 0.0 0
M  V30 93 C 0.8726 -12.577 0.0 0
M  V30 94 S -0.1026 -14.887 0.0 0
M  V30 95 Cl 1.54 -11.0369 0.0 0
M  V30 96 C 1.232 -13.963 0.0 0
M  V30 97 C 2.464 -14.6303 0.0 0
M  V30 98 O 3.6961 -13.655 0.0 0
M  V30 99 C 4.9281 -14.3223 0.0 0
M  V30 100 O 4.7741 -15.7597 0.0 0
M  V30 101 C 6.1601 -13.347 0.0 0
M  V30 102 Cl -1.232 -5.3388 0.0 0
M  V30 103 C -0.5646 -6.5708 0.0 0
M  V30 104 N -1.232 -7.9568 0.0 0
M  V30 105 C 0.8726 -6.4168 0.0 0
M  V30 106 S -0.1026 -8.7269 0.0 0
M  V30 107 Cl 1.54 -4.8767 0.0 0
M  V30 108 C 1.232 -7.8028 0.0 0
M  V30 109 C 2.464 -8.4702 0.0 0
M  V30 110 O 3.6961 -7.4948 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 7 8
M  V30 8 3 8 9
M  V30 9 1 10 11
M  V30 10 2 11 12
M  V30 11 1 11 13
M  V30 12 1 12 14
M  V30 13 1 13 15
M  V30 14 2 13 16
M  V30 15 1 16 17
M  V30 16 2 17 18
M  V30 17 1 17 19
M  V30 18 1 19 20
M  V30 19 1 20 21
M  V30 20 1 22 23
M  V30 21 2 23 24
M  V30 22 1 23 25
M  V30 23 1 24 26
M  V30 24 1 25 27
M  V30 25 2 25 28
M  V30 26 1 28 29
M  V30 27 2 29 30
M  V30 28 1 29 31
M  V30 29 1 31 32
M  V30 30 1 33 34
M  V30 31 2 34 35
M  V30 32 1 34 36
M  V30 33 1 35 37
M  V30 34 1 36 38
M  V30 35 2 36 39
M  V30 36 1 39 40
M  V30 37 2 40 41
M  V30 38 1 40 42
M  V30 39 1 43 44
M  V30 40 2 44 45
M  V30 41 1 44 46
M  V30 42 1 45 47
M  V30 43 1 46 48
M  V30 44 2 46 49
M  V30 45 1 49 50
M  V30 46 2 50 51
M  V30 47 1 50 52
M  V30 48 1 53 54
M  V30 49 2 54 55
M  V30 50 1 54 56
M  V30 51 1 55 57
M  V30 52 1 56 58
M  V30 53 2 56 59
M  V30 54 1 59 60
M  V30 55 1 60 61
M  V30 56 1 61 62
M  V30 57 2 62 63
M  V30 58 1 62 64
M  V30 59 1 63 65
M  V30 60 2 64 66
M  V30 61 1 64 67
M  V30 62 2 65 68
M  V30 63 2 65 69
M  V30 64 1 66 70
M  V30 65 2 67 71
M  V30 66 2 70 72
M  V30 67 1 73 74
M  V30 68 2 74 75
M  V30 69 1 74 76
M  V30 70 1 75 77
M  V30 71 1 76 78
M  V30 72 2 76 79
M  V30 73 1 79 80
M  V30 74 1 80 81
M  V30 75 1 81 82
M  V30 76 2 82 83
M  V30 77 1 82 84
M  V30 78 2 84 85
M  V30 79 1 84 86
M  V30 80 1 85 87
M  V30 81 2 86 88
M  V30 82 2 87 89
M  V30 83 1 90 91
M  V30 84 2 91 92
M  V30 85 1 91 93
M  V30 86 1 92 94
M  V30 87 1 93 95
M  V30 88 2 93 96
M  V30 89 1 96 97
M  V30 90 1 97 98
M  V30 91 1 98 99
M  V30 92 2 99 100
M  V30 93 1 99 101
M  V30 94 1 102 103
M  V30 95 2 103 104
M  V30 96 1 103 105
M  V30 97 1 104 106
M  V30 98 1 105 107
M  V30 99 2 105 108
M  V30 100 1 108 109
M  V30 101 1 109 110
M  V30 102 1 5 7
M  V30 103 1 14 16
M  V30 104 1 26 28
M  V30 105 1 37 39
M  V30 106 1 47 49
M  V30 107 1 57 59
M  V30 108 1 65 66
M  V30 109 1 71 72
M  V30 110 1 77 79
M  V30 111 1 88 89
M  V30 112 1 94 96
M  V30 113 1 106 108
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00064001.cdx

>  <name>
US20220000117A1-20220106-C00027

>  <Row No>
150

$$$$
US20220000117A1-20220106-C00028
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 106 108 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.6876 -1.2606 0.0 0
M  V30 3 N 0.0764 -2.6358 0.0 0
M  V30 4 C 2.1392 -1.146 0.0 0
M  V30 5 S 1.2224 -3.438 0.0 0
M  V30 6 Cl 2.8268 0.3438 0.0 0
M  V30 7 C 2.5212 -2.5212 0.0 0
M  V30 8 C 3.7818 -3.2088 0.0 0
M  V30 9 O 5.0424 -2.292 0.0 0
M  V30 10 N 3.6672 -4.6604 0.0 0
M  V30 11 C 6.303 -2.9796 0.0 0
M  V30 12 C 7.5637 -2.0628 0.0 0
M  V30 13 C 8.8243 -2.7504 0.0 0
M  V30 14 C 7.4491 -0.382 0.0 0
M  V30 15 C 10.0849 -1.8336 0.0 0
M  V30 16 C 8.7097 0.5348 0.0 0
M  V30 17 C 9.9703 -0.1528 0.0 0
M  V30 18 Cl -0.9168 8.5569 0.0 0
M  V30 19 C -0.2292 7.2963 0.0 0
M  V30 20 N -0.8404 5.921 0.0 0
M  V30 21 C 1.2224 7.4109 0.0 0
M  V30 22 S 0.3056 5.1188 0.0 0
M  V30 23 Cl 1.91 8.9007 0.0 0
M  V30 24 C 1.6044 6.0356 0.0 0
M  V30 25 C 2.865 5.348 0.0 0
M  V30 26 O 4.1256 6.2648 0.0 0
M  V30 27 N 2.7504 3.8964 0.0 0
M  V30 28 C 4.011 7.9457 0.0 0
M  V30 29 Cl -0.9168 -22.6147 0.0 0
M  V30 30 C -0.2292 -23.8753 0.0 0
M  V30 31 N -0.8404 -25.2505 0.0 0
M  V30 32 C 1.2224 -23.7607 0.0 0
M  V30 33 S 0.3056 -26.0527 0.0 0
M  V30 34 Cl 1.91 -22.2709 0.0 0
M  V30 35 C 1.6044 -25.1359 0.0 0
M  V30 36 C 2.865 -25.8235 0.0 0
M  V30 37 N 2.7504 -27.2751 0.0 0
M  V30 38 N 4.1256 -24.9067 0.0 0
M  V30 39 C 4.011 -23.2259 0.0 0
M  V30 40 C 5.2716 -22.3091 0.0 0
M  V30 41 Cl -0.9168 -38.5061 0.0 0
M  V30 42 C -0.2292 -39.7667 0.0 0
M  V30 43 N -0.8404 -41.1419 0.0 0
M  V30 44 C 1.2224 -39.6521 0.0 0
M  V30 45 S 0.3056 -41.9441 0.0 0
M  V30 46 Cl 1.91 -38.1623 0.0 0
M  V30 47 C 1.6044 -41.0273 0.0 0
M  V30 48 C 2.865 -41.7149 0.0 0
M  V30 49 N 4.1256 -40.7981 0.0 0
M  V30 50 N 2.7504 -43.1666 0.0 0
M  V30 51 C 5.3862 -41.4857 0.0 0
M  V30 52 Cl -0.9168 -6.4176 0.0 0
M  V30 53 C -0.2292 -7.6783 0.0 0
M  V30 54 N -0.8404 -9.0535 0.0 0
M  V30 55 C 1.2224 -7.5637 0.0 0
M  V30 56 S 0.3056 -9.8557 0.0 0
M  V30 57 Cl 1.91 -6.0738 0.0 0
M  V30 58 C 1.6044 -8.9389 0.0 0
M  V30 59 C 2.865 -9.6265 0.0 0
M  V30 60 N 2.7504 -11.0781 0.0 0
M  V30 61 N 4.1256 -8.7097 0.0 0
M  V30 62 Cl -0.9168 -14.3634 0.0 0
M  V30 63 C -0.2292 -15.624 0.0 0
M  V30 64 N -0.8404 -16.9992 0.0 0
M  V30 65 C 1.2224 -15.5094 0.0 0
M  V30 66 S 0.3056 -17.8014 0.0 0
M  V30 67 Cl 1.91 -14.0196 0.0 0
M  V30 68 C 1.6044 -16.8846 0.0 0
M  V30 69 C 2.865 -17.5722 0.0 0
M  V30 70 N 2.7504 -19.0238 0.0 0
M  V30 71 N 4.1256 -16.6554 0.0 0
M  V30 72 Cl -0.9168 16.8082 0.0 0
M  V30 73 C -0.2292 15.5476 0.0 0
M  V30 74 N -0.8404 14.1724 0.0 0
M  V30 75 C 1.2224 15.6622 0.0 0
M  V30 76 S 0.3056 13.3701 0.0 0
M  V30 77 Cl 1.91 17.152 0.0 0
M  V30 78 C 1.6044 14.287 0.0 0
M  V30 79 C 2.865 13.5993 0.0 0
M  V30 80 O 2.7504 12.1477 0.0 0
M  V30 81 C 4.1256 14.5162 0.0 0
M  V30 82 C 5.3862 13.8285 0.0 0
M  V30 83 C 6.6468 14.7454 0.0 0
M  V30 84 C 5.2716 12.3769 0.0 0
M  V30 85 C 6.5322 16.4262 0.0 0
M  V30 86 C 7.9075 14.0578 0.0 0
M  V30 87 C 6.5322 11.6893 0.0 0
M  V30 88 N 6.4176 18.107 0.0 0
M  V30 89 C 7.7929 12.6061 0.0 0
M  V30 90 Cl -0.9168 -30.2548 0.0 0
M  V30 91 C -0.2292 -31.5154 0.0 0
M  V30 92 N -0.8404 -32.8906 0.0 0
M  V30 93 C 1.2224 -31.4008 0.0 0
M  V30 94 S 0.3056 -33.6928 0.0 0
M  V30 95 Cl 1.91 -29.911 0.0 0
M  V30 96 C 1.6044 -32.776 0.0 0
M  V30 97 C 2.865 -33.4636 0.0 0
M  V30 98 N 2.7504 -34.9152 0.0 0
M  V30 99 C 4.1256 -32.5468 0.0 0
M  V30 100 C 5.3862 -33.2344 0.0 0
M  V30 101 C 5.2716 -34.686 0.0 0
M  V30 102 C 6.6468 -32.3176 0.0 0
M  V30 103 C 6.5322 -35.3737 0.0 0
M  V30 104 C 7.9075 -33.0052 0.0 0
M  V30 105 C 7.7929 -34.4568 0.0 0
M  V30 106 Cl 5.1952 -18.3362 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 2 8 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 2 15 17
M  V30 17 1 18 19
M  V30 18 2 19 20
M  V30 19 1 19 21
M  V30 20 1 20 22
M  V30 21 1 21 23
M  V30 22 2 21 24
M  V30 23 1 24 25
M  V30 24 1 25 26
M  V30 25 2 25 27
M  V30 26 1 26 28
M  V30 27 1 29 30
M  V30 28 2 30 31
M  V30 29 1 30 32
M  V30 30 1 31 33
M  V30 31 1 32 34
M  V30 32 2 32 35
M  V30 33 1 35 36
M  V30 34 2 36 37
M  V30 35 1 36 38
M  V30 36 1 38 39
M  V30 37 1 39 40
M  V30 38 1 41 42
M  V30 39 2 42 43
M  V30 40 1 42 44
M  V30 41 1 43 45
M  V30 42 1 44 46
M  V30 43 2 44 47
M  V30 44 1 47 48
M  V30 45 2 48 49
M  V30 46 1 48 50
M  V30 47 1 49 51
M  V30 48 1 52 53
M  V30 49 2 53 54
M  V30 50 1 53 55
M  V30 51 1 54 56
M  V30 52 1 55 57
M  V30 53 2 55 58
M  V30 54 1 58 59
M  V30 55 2 59 60
M  V30 56 1 59 61
M  V30 57 1 62 63
M  V30 58 2 63 64
M  V30 59 1 63 65
M  V30 60 1 64 66
M  V30 61 1 65 67
M  V30 62 2 65 68
M  V30 63 1 68 69
M  V30 64 2 69 70
M  V30 65 1 69 71
M  V30 66 1 72 73
M  V30 67 2 73 74
M  V30 68 1 73 75
M  V30 69 1 74 76
M  V30 70 1 75 77
M  V30 71 2 75 78
M  V30 72 1 78 79
M  V30 73 2 79 80
M  V30 74 1 79 81
M  V30 75 1 81 82
M  V30 76 2 82 83
M  V30 77 1 82 84
M  V30 78 1 83 85
M  V30 79 1 83 86
M  V30 80 2 84 87
M  V30 81 3 85 88
M  V30 82 2 86 89
M  V30 83 1 90 91
M  V30 84 2 91 92
M  V30 85 1 91 93
M  V30 86 1 92 94
M  V30 87 1 93 95
M  V30 88 2 93 96
M  V30 89 1 96 97
M  V30 90 2 97 98
M  V30 91 1 97 99
M  V30 92 1 99 100
M  V30 93 2 100 101
M  V30 94 1 100 102
M  V30 95 1 101 103
M  V30 96 2 102 104
M  V30 97 2 103 105
M  V30 98 1 5 7
M  V30 99 1 16 17
M  V30 100 1 22 24
M  V30 101 1 33 35
M  V30 102 1 45 47
M  V30 103 1 56 58
M  V30 104 1 66 68
M  V30 105 1 76 78
M  V30 106 1 87 89
M  V30 107 1 94 96
M  V30 108 1 104 105
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00064002.cdx

>  <name>
US20220000117A1-20220106-C00028

>  <Row No>
151

$$$$
US20220000118A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000118A1-20220106-C00001

>  <Row No>
152

$$$$
US20220000118A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000118A1-20220106-C00002

>  <Row No>
153

$$$$
US20220000118A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4637 0.0 0
M  V30 3 N -1.3677 -2.1956 0.0 0
M  V30 4 N 1.2237 -2.1956 0.0 0
M  V30 5 C -2.6995 -1.4157 0.0 0
M  V30 6 C 1.1877 -3.6593 0.0 0
M  V30 7 C -4.0313 -2.1476 0.0 0
M  V30 8 C -2.7355 0.1199 0.0 0
M  V30 9 C -0.1439 -4.3792 0.0 0
M  V30 10 C 2.4475 -4.3792 0.0 0
M  V30 11 C -5.363 -1.3677 0.0 0
M  V30 12 C -4.0672 0.8998 0.0 0
M  V30 13 C -0.1799 -5.8429 0.0 0
M  V30 14 C 2.4115 -5.8429 0.0 0
M  V30 15 C -6.6948 -2.0996 0.0 0
M  V30 16 C -5.399 0.1679 0.0 0
M  V30 17 C 1.0798 -6.5748 0.0 0
M  V30 18 C -6.7308 -3.5633 0.0 0
M  V30 19 C -8.1585 -1.5957 0.0 0
M  V30 20 C 1.0438 -8.0386 0.0 0
M  V30 21 N -8.1945 -3.9953 0.0 0
M  V30 22 C -9.0704 -2.7715 0.0 0
M  V30 23 C 2.3036 -8.7584 0.0 0
M  V30 24 N -10.6061 -2.7355 0.0 0
M  V30 25 C 3.5633 -7.9786 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 12 16
M  V30 26 1 14 17
M  V30 27 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000118A1-20220106-C00004

>  <Row No>
154

$$$$
US20220000118A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4664 0.0 0
M  V30 3 N -1.3703 -2.1876 0.0 0
M  V30 4 N 1.226 -2.1876 0.0 0
M  V30 5 C -2.7045 -1.4183 0.0 0
M  V30 6 C 2.4881 -1.4183 0.0 0
M  V30 7 C -4.0387 -2.1396 0.0 0
M  V30 8 C -2.7406 0.1202 0.0 0
M  V30 9 C 3.7503 -2.1396 0.0 0
M  V30 10 C 2.4521 0.1202 0.0 0
M  V30 11 C -5.373 -1.3582 0.0 0
M  V30 12 C -4.0748 0.9015 0.0 0
M  V30 13 C 5.0124 -1.3582 0.0 0
M  V30 14 C 3.7142 0.9015 0.0 0
M  V30 15 C -6.7072 -2.0794 0.0 0
M  V30 16 C -5.4091 0.1803 0.0 0
M  V30 17 C 6.2745 -2.0794 0.0 0
M  V30 18 C 4.9763 0.1803 0.0 0
M  V30 19 C -6.7433 -3.5459 0.0 0
M  V30 20 C -8.1737 -1.5746 0.0 0
M  V30 21 C 6.2384 -3.5459 0.0 0
M  V30 22 C 7.6689 -1.5746 0.0 0
M  V30 23 N -8.2098 -3.9786 0.0 0
M  V30 24 C -9.0872 -2.7526 0.0 0
M  V30 25 N 7.6328 -3.9786 0.0 0
M  V30 26 C 8.5103 -2.7526 0.0 0
M  V30 27 N -10.6258 -2.7165 0.0 0
M  V30 28 C 9.9767 -2.7165 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 2 17 21
M  V30 21 1 17 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 24 27
M  V30 27 1 26 28
M  V30 28 1 12 16
M  V30 29 1 14 18
M  V30 30 2 23 24
M  V30 31 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000118A1-20220106-C00005

>  <Row No>
155

$$$$
US20220000118A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C 1.2506 0.7622 0.0 0
M  V30 3 C 1.2148 2.2868 0.0 0
M  V30 4 C 2.5012 0.0476 0.0 0
M  V30 5 C 2.4655 3.0491 0.0 0
M  V30 6 C 3.7518 0.8099 0.0 0
M  V30 7 N 2.4297 4.5736 0.0 0
M  V30 8 C 3.7161 2.3344 0.0 0
M  V30 9 C 5.0024 0.0952 0.0 0
M  V30 10 C 1.1076 5.3478 0.0 0
M  V30 11 O 1.0719 6.8724 0.0 0
M  V30 12 N -0.2143 4.6332 0.0 0
M  V30 13 C -1.5364 5.3955 0.0 0
M  V30 14 C -2.8585 4.6808 0.0 0
M  V30 15 C -1.5722 6.92 0.0 0
M  V30 16 C -4.1806 5.4431 0.0 0
M  V30 17 C -2.8942 7.6942 0.0 0
M  V30 18 C -5.5027 4.7285 0.0 0
M  V30 19 C -4.2163 6.9677 0.0 0
M  V30 20 C -5.5384 3.2754 0.0 0
M  V30 21 C -6.9558 5.2287 0.0 0
M  V30 22 N -6.9915 2.8466 0.0 0
M  V30 23 C -7.861 4.0615 0.0 0
M  V30 24 N -9.3856 4.0972 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 6 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000118A1-20220106-C00006

>  <Row No>
156

$$$$
US20220000118A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 1.4507 0.0356 0.0 0
M  V30 3 F 1.415 -1.415 0.0 0
M  V30 4 F 2.9014 0.0713 0.0 0
M  V30 5 C 1.415 1.5577 0.0 0
M  V30 6 C 2.6636 2.3306 0.0 0
M  V30 7 C 0.0951 2.3306 0.0 0
M  V30 8 C 2.6279 3.8527 0.0 0
M  V30 9 C 3.9121 1.6053 0.0 0
M  V30 10 C 0.0594 3.8527 0.0 0
M  V30 11 C 1.308 4.6137 0.0 0
M  V30 12 N 1.2723 6.1358 0.0 0
M  V30 13 C -0.0475 6.9087 0.0 0
M  V30 14 O -0.0832 8.4308 0.0 0
M  V30 15 N -1.3674 6.1834 0.0 0
M  V30 16 C -2.6874 6.9444 0.0 0
M  V30 17 C -4.0073 6.219 0.0 0
M  V30 18 C -2.723 8.4665 0.0 0
M  V30 19 C -5.3272 6.9801 0.0 0
M  V30 20 C -4.0429 9.2394 0.0 0
M  V30 21 C -6.6471 6.2547 0.0 0
M  V30 22 C -5.3629 8.5021 0.0 0
M  V30 23 C -6.6828 4.804 0.0 0
M  V30 24 C -8.0978 6.7541 0.0 0
M  V30 25 N -8.1335 4.3759 0.0 0
M  V30 26 C -5.4342 4.0905 0.0 0
M  V30 27 C -9.0016 5.5888 0.0 0
M  V30 28 N -10.5236 5.6245 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 2 7 10
M  V30 10 2 8 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 27 28
M  V30 28 1 10 11
M  V30 29 1 20 22
M  V30 30 2 25 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000118A1-20220106-C00007

>  <Row No>
157

$$$$
US20220000118A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0362 1.5459 0.0 0
M  V30 3 C -1.3768 2.3309 0.0 0
M  V30 4 C 1.2319 2.3309 0.0 0
M  V30 5 C -2.7174 1.6063 0.0 0
M  V30 6 C 2.5 1.6063 0.0 0
M  V30 7 C -2.7537 0.1328 0.0 0
M  V30 8 C -4.058 2.3913 0.0 0
M  V30 9 C 2.4638 0.1328 0.0 0
M  V30 10 C 3.7682 2.3793 0.0 0
M  V30 11 C -4.0943 -0.5918 0.0 0
M  V30 12 C -5.3987 1.6546 0.0 0
M  V30 13 C 3.732 -0.5918 0.0 0
M  V30 14 C 5.0363 1.6546 0.0 0
M  V30 15 C -5.4349 0.1932 0.0 0
M  V30 16 C 5.0001 0.1811 0.0 0
M  V30 17 C -6.7755 -0.5314 0.0 0
M  V30 18 C 6.2683 -0.5434 0.0 0
M  V30 19 C -6.8118 -2.0048 0.0 0
M  V30 20 C -8.249 -0.0241 0.0 0
M  V30 21 C 6.7031 -1.9445 0.0 0
M  V30 22 C 7.4519 0.3744 0.0 0
M  V30 23 N -8.2852 -2.4396 0.0 0
M  V30 24 C -9.1669 -1.2077 0.0 0
M  V30 25 N 8.1765 -1.9082 0.0 0
M  V30 26 C 8.6355 -0.471 0.0 0
M  V30 27 N -10.7129 -1.1715 0.0 0
M  V30 28 C 10.109 -0.4347 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 11 15
M  V30 15 2 13 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 17 20
M  V30 20 2 18 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 24 27
M  V30 27 1 26 28
M  V30 28 1 12 15
M  V30 29 1 14 16
M  V30 30 2 23 24
M  V30 31 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000118A1-20220106-C00009

>  <Row No>
158

$$$$
US20220000118A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 34 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0362 1.5477 0.0 0
M  V30 3 C 1.2333 2.3216 0.0 0
M  V30 4 C -1.3784 2.3216 0.0 0
M  V30 5 C 2.503 1.584 0.0 0
M  V30 6 C -2.7206 1.5961 0.0 0
M  V30 7 C 2.4667 0.1088 0.0 0
M  V30 8 C 3.7726 2.37 0.0 0
M  V30 9 C -2.7569 0.1209 0.0 0
M  V30 10 C -4.0628 2.382 0.0 0
M  V30 11 C 3.7363 -0.6166 0.0 0
M  V30 12 C 5.0423 1.6323 0.0 0
M  V30 13 C -4.0991 -0.6045 0.0 0
M  V30 14 C -5.405 1.6444 0.0 0
M  V30 15 C 5.006 0.1571 0.0 0
M  V30 16 C 3.7001 -2.0918 0.0 0
M  V30 17 C -5.4413 0.1692 0.0 0
M  V30 18 C 6.2756 -0.5683 0.0 0
M  V30 19 N 2.5513 -3.0592 0.0 0
M  V30 20 C 4.9697 -2.8174 0.0 0
M  V30 21 C -6.7835 -0.5562 0.0 0
M  V30 22 C 6.2393 -2.0435 0.0 0
M  V30 23 C 3.1438 -4.4014 0.0 0
M  V30 24 N 4.619 -4.2563 0.0 0
M  V30 25 C -6.8198 -2.0314 0.0 0
M  V30 26 C -8.2587 -0.0483 0.0 0
M  V30 27 N 2.37 -5.671 0.0 0
M  V30 28 N -8.295 -2.4667 0.0 0
M  V30 29 C -9.1777 -1.2333 0.0 0
M  V30 30 N -10.7254 -1.197 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 11 15
M  V30 15 1 11 16
M  V30 16 2 13 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 2 16 20
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 2 21 25
M  V30 25 1 21 26
M  V30 26 1 23 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 29 30
M  V30 30 1 12 15
M  V30 31 1 14 17
M  V30 32 1 20 22
M  V30 33 2 23 24
M  V30 34 2 28 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000118A1-20220106-C00011

>  <Row No>
159

$$$$
US20220000118A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 5 5 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C -0.942 -1.201 0.0 0
M  V30 3 C 1.413 -0.4239 0.0 0
M  V30 4 N -0.0706 -2.4021 0.0 0
M  V30 5 C 1.3776 -1.9075 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 4 5
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000118A1-20220106-C00012

>  <Row No>
160

$$$$
US20220000118A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.758 -1.291 0.0 0
M  V30 3 N 2.2503 -1.2791 0.0 0
M  V30 4 C -0.0473 -2.5583 0.0 0
M  V30 5 C 2.9728 0.0592 0.0 0
M  V30 6 ? 2.9847 -2.5701 0.0 0
M  V30 7 O 8.812 0.379 0.0 0
M  V30 8 C 8.0303 -0.9119 0.0 0
M  V30 9 N 6.5142 -0.9001 0.0 0
M  V30 10 C 8.7528 -2.1793 0.0 0
M  V30 11 C 5.7325 -2.1674 0.0 0
M  V30 12 ? 5.7325 0.4145 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 7 8
M  V30 7 1 8 9
M  V30 8 1 8 10
M  V30 9 1 9 11
M  V30 10 1 9 12
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000118A1-20220106-C00013

>  <Row No>
161

$$$$
US20220000118A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 5 4 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -1.0862 1.0862 0.0 0
M  V30 3 O -1.4791 -0.3582 0.0 0
M  V30 4 C 0.3582 -1.4098 0.0 0
M  V30 5 ? 1.04 1.0631 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000118A1-20220106-C00014

>  <Row No>
162

$$$$
US20220000118A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 4 3 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0 CFG=2
M  V30 2 O -0.0356 1.5223 0.0 0
M  V30 3 C -1.3201 -0.7255 0.0 0
M  V30 4 ? 1.2726 -0.7373 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4 CFG=1
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 1)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00035001.cdx

>  <name>
US20220000118A1-20220106-C00015

>  <Row No>
163

$$$$
US20220000118A1-20220106-C00016
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000118A1-20220106-C00016

>  <Row No>
164

$$$$
US20220000118A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000118A1-20220106-C00017

>  <Row No>
165

$$$$
US20220000118A1-20220106-C00019
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4634 0.0 0
M  V30 3 N -1.5234 -1.8233 0.0 0
M  V30 4 N 1.2235 -2.1831 0.0 0
M  V30 5 C -2.8549 -1.0556 0.0 0
M  V30 6 C 1.1875 -3.6466 0.0 0
M  V30 7 C -4.1864 -1.7873 0.0 0
M  V30 8 C -2.8909 0.4798 0.0 0
M  V30 9 C -0.1439 -4.3663 0.0 0
M  V30 10 C 2.447 -4.3663 0.0 0
M  V30 11 C -5.5179 -1.0076 0.0 0
M  V30 12 C -4.2224 1.2715 0.0 0
M  V30 13 C -0.1799 -5.8298 0.0 0
M  V30 14 C 2.411 -5.8298 0.0 0
M  V30 15 C -6.8494 -1.7393 0.0 0
M  V30 16 C -5.5539 0.5278 0.0 0
M  V30 17 C 1.0795 -6.5495 0.0 0
M  V30 18 C -7.0413 -3.1907 0.0 0
M  V30 19 C -8.2528 -1.0795 0.0 0
M  V30 20 C 1.0436 -8.0129 0.0 0
M  V30 21 N -8.5407 -3.4666 0.0 0
M  V30 22 C -9.2845 -2.1471 0.0 0
M  V30 23 C 2.3031 -8.7327 0.0 0
M  V30 24 N -10.8199 -2.1112 0.0 0
M  V30 25 C 3.5626 -7.953 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 12 16
M  V30 26 1 14 17
M  V30 27 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00039001.cdx

>  <name>
US20220000118A1-20220106-C00019

>  <Row No>
166

$$$$
US20220000118A1-20220106-C00020
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4658 0.0 0
M  V30 3 N -1.5259 -1.8263 0.0 0
M  V30 4 N 1.2255 -2.1867 0.0 0
M  V30 5 C -2.8596 -1.0453 0.0 0
M  V30 6 C 2.4871 -1.4177 0.0 0
M  V30 7 C -4.1933 -1.7662 0.0 0
M  V30 8 C -2.8956 0.4926 0.0 0
M  V30 9 C 3.7487 -2.1387 0.0 0
M  V30 10 C 2.4511 0.1201 0.0 0
M  V30 11 C -5.527 -0.9852 0.0 0
M  V30 12 C -4.2293 1.2736 0.0 0
M  V30 13 C 5.0103 -1.3697 0.0 0
M  V30 14 C 3.7127 0.8891 0.0 0
M  V30 15 C -6.8606 -1.7061 0.0 0
M  V30 16 C -5.563 0.5527 0.0 0
M  V30 17 C 6.2719 -2.0906 0.0 0
M  V30 18 C 4.9743 0.1682 0.0 0
M  V30 19 C -7.0529 -3.16 0.0 0
M  V30 20 C -8.2664 -1.0453 0.0 0
M  V30 21 C 6.2359 -3.5565 0.0 0
M  V30 22 C 7.6657 -1.586 0.0 0
M  V30 23 N -8.5548 -3.4363 0.0 0
M  V30 24 C -9.2997 -2.1146 0.0 0
M  V30 25 N 7.6296 -3.989 0.0 0
M  V30 26 C 8.5067 -2.7635 0.0 0
M  V30 27 N -10.8377 -2.0786 0.0 0
M  V30 28 C 9.9726 -2.7274 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 2 17 21
M  V30 21 1 17 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 24 27
M  V30 27 1 26 28
M  V30 28 1 12 16
M  V30 29 1 14 18
M  V30 30 2 23 24
M  V30 31 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00040001.cdx

>  <name>
US20220000118A1-20220106-C00020

>  <Row No>
167

$$$$
US20220000118A1-20220106-C00021
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C 1.2486 0.761 0.0 0
M  V30 3 C 1.2129 2.2832 0.0 0
M  V30 4 C 2.4973 0.0356 0.0 0
M  V30 5 C 2.4616 3.0443 0.0 0
M  V30 6 C 3.7459 0.8086 0.0 0
M  V30 7 N 2.4259 4.5665 0.0 0
M  V30 8 C 3.7103 2.3189 0.0 0
M  V30 9 C 4.9946 0.0832 0.0 0
M  V30 10 C 1.1059 5.3395 0.0 0
M  V30 11 O 1.0702 6.8616 0.0 0
M  V30 12 N -0.3686 4.9827 0.0 0
M  V30 13 C -1.6886 5.7557 0.0 0
M  V30 14 C -3.0086 5.0303 0.0 0
M  V30 15 C -1.7243 7.2779 0.0 0
M  V30 16 C -4.3286 5.8033 0.0 0
M  V30 17 C -3.0443 8.0508 0.0 0
M  V30 18 C -5.6487 5.0778 0.0 0
M  V30 19 C -4.3643 7.3254 0.0 0
M  V30 20 C -5.8389 3.6389 0.0 0
M  V30 21 C -7.04 5.7319 0.0 0
M  V30 22 N -7.3254 3.3654 0.0 0
M  V30 23 C -8.0627 4.6735 0.0 0
M  V30 24 N -9.5849 4.7092 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 6 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00041001.cdx

>  <name>
US20220000118A1-20220106-C00021

>  <Row No>
168

$$$$
US20220000118A1-20220106-C00022
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 1.4503 0.0356 0.0 0
M  V30 3 F 1.4147 -1.4147 0.0 0
M  V30 4 F 2.9007 0.0713 0.0 0
M  V30 5 C 1.4147 1.5573 0.0 0
M  V30 6 C 2.6629 2.33 0.0 0
M  V30 7 C 0.0951 2.33 0.0 0
M  V30 8 C 2.6273 3.8517 0.0 0
M  V30 9 C 3.9112 1.6049 0.0 0
M  V30 10 C 0.0594 3.8517 0.0 0
M  V30 11 C 1.3077 4.6126 0.0 0
M  V30 12 N 1.272 6.1343 0.0 0
M  V30 13 C -0.0475 6.907 0.0 0
M  V30 14 O -0.0832 8.4287 0.0 0
M  V30 15 N -1.5216 6.5504 0.0 0
M  V30 16 C -2.8412 7.3231 0.0 0
M  V30 17 C -4.1608 6.5979 0.0 0
M  V30 18 C -2.8769 8.8448 0.0 0
M  V30 19 C -5.4804 7.3707 0.0 0
M  V30 20 C -4.1965 9.6175 0.0 0
M  V30 21 C -6.8 6.6455 0.0 0
M  V30 22 C -5.5161 8.8924 0.0 0
M  V30 23 C -6.9902 5.207 0.0 0
M  V30 24 C -8.1909 7.2993 0.0 0
M  V30 25 N -8.4763 4.9336 0.0 0
M  V30 26 C -5.9322 4.2559 0.0 0
M  V30 27 C -9.2133 6.2413 0.0 0
M  V30 28 N -10.735 6.2769 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 2 7 10
M  V30 10 2 8 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 27 28
M  V30 28 1 10 11
M  V30 29 1 20 22
M  V30 30 2 25 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00042001.cdx

>  <name>
US20220000118A1-20220106-C00022

>  <Row No>
169

$$$$
US20220000118A1-20220106-C00024
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 1.534 0.0 0
M  V30 3 C -1.3063 2.6247 0.0 0
M  V30 4 C 1.1625 2.6247 0.0 0
M  V30 5 C -2.7925 2.0854 0.0 0
M  V30 6 C 2.421 1.9056 0.0 0
M  V30 7 C -2.8284 0.6232 0.0 0
M  V30 8 C -4.1228 2.8644 0.0 0
M  V30 9 C 2.385 0.4434 0.0 0
M  V30 10 C 3.6794 2.6846 0.0 0
M  V30 11 C -4.1588 -0.0958 0.0 0
M  V30 12 C -5.4532 2.1333 0.0 0
M  V30 13 C 3.6434 -0.2636 0.0 0
M  V30 14 C 4.9378 1.9655 0.0 0
M  V30 15 C -5.4891 0.6711 0.0 0
M  V30 16 C 4.9019 0.5033 0.0 0
M  V30 17 C -6.8195 -0.0479 0.0 0
M  V30 18 C 6.1603 -0.2157 0.0 0
M  V30 19 C -7.0113 -1.4981 0.0 0
M  V30 20 C -8.2218 0.6112 0.0 0
M  V30 21 C 6.5199 -1.6299 0.0 0
M  V30 22 C 7.3828 0.6232 0.0 0
M  V30 23 N -8.5094 -1.7738 0.0 0
M  V30 24 C -9.2525 -0.4554 0.0 0
M  V30 25 N 7.9821 -1.6779 0.0 0
M  V30 26 C 8.5094 -0.2756 0.0 0
M  V30 27 N -10.7866 -0.4194 0.0 0
M  V30 28 C 9.9716 -0.2397 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 11 15
M  V30 15 2 13 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 17 20
M  V30 20 2 18 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 24 27
M  V30 27 1 26 28
M  V30 28 1 12 15
M  V30 29 1 14 16
M  V30 30 2 23 24
M  V30 31 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00044001.cdx

>  <name>
US20220000118A1-20220106-C00024

>  <Row No>
170

$$$$
US20220000118A1-20220106-C00026
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 34 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0362 1.5452 0.0 0
M  V30 3 C 1.2314 2.33 0.0 0
M  V30 4 C -1.3762 2.33 0.0 0
M  V30 5 C 2.499 1.6056 0.0 0
M  V30 6 C -2.7163 1.6056 0.0 0
M  V30 7 C 2.4628 0.1327 0.0 0
M  V30 8 C 3.7666 2.3782 0.0 0
M  V30 9 C -2.7525 0.1327 0.0 0
M  V30 10 C -4.0563 2.3903 0.0 0
M  V30 11 C 3.7304 -0.5915 0.0 0
M  V30 12 C 5.0342 1.6539 0.0 0
M  V30 13 C -4.0925 -0.5915 0.0 0
M  V30 14 C -5.3964 1.6539 0.0 0
M  V30 15 C 4.998 0.181 0.0 0
M  V30 16 C 3.6942 -2.0644 0.0 0
M  V30 17 C -5.4326 0.181 0.0 0
M  V30 18 C 6.2656 -0.5432 0.0 0
M  V30 19 N 2.5473 -3.0302 0.0 0
M  V30 20 C 4.9618 -2.7887 0.0 0
M  V30 21 C -6.7727 -0.5432 0.0 0
M  V30 22 C 6.2294 -2.0161 0.0 0
M  V30 23 C 3.1388 -4.3702 0.0 0
M  V30 24 N 4.6117 -4.2253 0.0 0
M  V30 25 C -6.9658 -2.004 0.0 0
M  V30 26 C -8.1851 0.1207 0.0 0
M  V30 27 N 2.0644 -5.505 0.0 0
M  V30 28 N -8.4749 -2.2817 0.0 0
M  V30 29 C -9.2234 -0.9537 0.0 0
M  V30 30 N -10.7687 -0.9175 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 11 15
M  V30 15 1 11 16
M  V30 16 2 13 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 2 16 20
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 2 21 25
M  V30 25 1 21 26
M  V30 26 1 23 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 29 30
M  V30 30 1 12 15
M  V30 31 1 14 17
M  V30 32 1 20 22
M  V30 33 2 23 24
M  V30 34 2 28 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00046001.cdx

>  <name>
US20220000118A1-20220106-C00026

>  <Row No>
171

$$$$
US20220000118A1-20220106-C00027
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 31 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4635 0.0 0 CFG=2
M  V30 3 C 1.2236 -2.1953 0.0 0
M  V30 4 C -1.3675 -2.1953 0.0 0
M  V30 5 O 1.1876 -3.6588 0.0 0
M  V30 6 C 2.4832 -1.4155 0.0 0
M  V30 7 C 3.7428 -2.1473 0.0 0
M  V30 8 C 2.4472 0.1199 0.0 0
M  V30 9 C 5.0024 -1.3675 0.0 0
M  V30 10 C 3.7068 0.8997 0.0 0
M  V30 11 N 6.262 -2.0873 0.0 0 CHG=1
M  V30 12 C 4.9664 0.1679 0.0 0
M  V30 13 O 6.226 -3.5508 0.0 0
M  V30 14 O 7.5216 -1.3075 0.0 0 CHG=-1
M  V30 15 O -4.6065 3.3589 0.0 0
M  V30 16 N -4.6425 4.8944 0.0 0 CHG=1
M  V30 17 O -3.3829 5.6621 0.0 0 CHG=-1
M  V30 18 C -5.974 5.6621 0.0 0
M  V30 19 C -7.3056 4.9424 0.0 0
M  V30 20 C -6.01 7.1977 0.0 0
M  V30 21 C -8.6372 5.7101 0.0 0
M  V30 22 C -7.3416 7.9774 0.0 0
M  V30 23 C -9.9688 4.9904 0.0 0
M  V30 24 C -8.6732 7.2456 0.0 0
M  V30 25 O -10.0048 3.5268 0.0 0
M  V30 26 C -11.3004 5.7581 0.0 0
M  V30 27 C -12.6319 5.0383 0.0 0
M  V30 28 C 4.2226 0.0 0.0 0
M  V30 29 ? 4.9664 1.3075 0.0 0
M  V30 30 C -6.8138 7.0057 0.0 0
M  V30 31 ? -6.07 8.3133 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=3
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 2 6 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 9 11
M  V30 11 2 9 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 2 15 16
M  V30 15 1 16 17
M  V30 16 1 16 18
M  V30 17 2 18 19
M  V30 18 1 18 20
M  V30 19 1 19 21
M  V30 20 2 20 22
M  V30 21 1 21 23
M  V30 22 2 21 24
M  V30 23 2 23 25
M  V30 24 1 23 26
M  V30 25 1 26 27
M  V30 26 1 28 29
M  V30 27 1 30 31
M  V30 28 1 10 12
M  V30 29 1 22 24
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00047001.cdx

>  <name>
US20220000118A1-20220106-C00027

>  <Row No>
172

$$$$
US20220000118A1-20220106-C00028
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 145 140 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.0825 -1.4027 0.0 0 CFG=2
M  V30 3 C 1.1276 -2.0353 0.0 0
M  V30 4 C -1.4577 -2.0353 0.0 0
M  V30 5 O 1.0451 -3.438 0.0 0
M  V30 6 C 2.3378 -1.2376 0.0 0
M  V30 7 C 3.548 -1.8702 0.0 0
M  V30 8 C 2.2553 0.33 0.0 0
M  V30 9 C 4.7582 -1.0726 0.0 0
M  V30 10 C 3.4655 1.1276 0.0 0
M  V30 11 N 5.9683 -1.7052 0.0 0 CHG=1
M  V30 12 C 4.6756 0.495 0.0 0
M  V30 13 O 5.8858 -3.1079 0.0 0
M  V30 14 O 7.1785 -0.9076 0.0 0 CHG=-1
M  V30 15 O 10.7815 -17.8226 0.0 0
M  V30 16 N 10.699 -16.2548 0.0 0 CHG=1
M  V30 17 O 11.9092 -15.4572 0.0 0 CHG=-1
M  V30 18 C 9.3238 -15.4572 0.0 0
M  V30 19 C 7.9486 -16.0898 0.0 0
M  V30 20 C 9.2413 -13.8895 0.0 0
M  V30 21 C 6.5734 -15.2922 0.0 0
M  V30 22 C 7.8661 -13.0919 0.0 0
M  V30 23 C 5.1982 -15.9248 0.0 0
M  V30 24 C 6.4909 -13.7245 0.0 0
M  V30 25 N 3.768 -15.2372 0.0 0
M  V30 26 C 4.9507 -17.3275 0.0 0
M  V30 27 C 2.6953 -16.2548 0.0 0
M  V30 28 C 3.3554 -13.697 0.0 0
M  V30 29 N 3.4105 -17.5475 0.0 0
M  V30 30 C 5.9683 -18.2076 0.0 0
M  V30 31 N 1.1276 -16.0073 0.0 0
M  V30 32 O 1.8427 -13.1744 0.0 0
M  V30 33 O 4.3731 -12.6243 0.0 0
M  V30 34 C 0.1375 -17.08 0.0 0
M  V30 35 C 0.4675 -14.5771 0.0 0
M  V30 36 C 3.9605 -11.0841 0.0 0
M  V30 37 O 0.605 -18.3452 0.0 0
M  V30 38 O -1.4027 -16.8049 0.0 0
M  V30 39 O -1.1001 -14.3021 0.0 0
M  V30 40 O 1.2651 -13.2844 0.0 0
M  V30 41 C 3.548 -9.5439 0.0 0
M  V30 42 C 2.4478 -10.5615 0.0 0
M  V30 43 C 4.9782 -10.0114 0.0 0
M  V30 44 C -2.3928 -17.8776 0.0 0
M  V30 45 C 0.605 -11.8542 0.0 0
M  V30 46 C -3.3829 -18.9502 0.0 0
M  V30 47 C -1.9252 -19.1428 0.0 0
M  V30 48 C -3.933 -17.6025 0.0 0
M  V30 49 C -0.055 -10.424 0.0 0
M  V30 50 C -0.9626 -11.5792 0.0 0
M  V30 51 C 1.4027 -10.6165 0.0 0
M  V30 52 O 10.1214 -10.1214 0.0 0
M  V30 53 N 10.0389 -8.5537 0.0 0 CHG=1
M  V30 54 O 11.2491 -7.7561 0.0 0 CHG=-1
M  V30 55 C 8.6637 -7.7561 0.0 0
M  V30 56 C 7.2885 -8.3887 0.0 0
M  V30 57 C 8.5812 -6.1884 0.0 0
M  V30 58 C 5.9133 -7.5911 0.0 0
M  V30 59 C 7.206 -5.3907 0.0 0
M  V30 60 C 4.5381 -8.2237 0.0 0
M  V30 61 C 5.8308 -6.0233 0.0 0
M  V30 62 N 3.1079 -7.5361 0.0 0
M  V30 63 C 4.2906 -9.6264 0.0 0
M  V30 64 C 2.0353 -8.5537 0.0 0
M  V30 65 C 2.6953 -5.9958 0.0 0
M  V30 66 N 2.7504 -9.8464 0.0 0
M  V30 67 C 5.3082 -10.5065 0.0 0
M  V30 68 N 0.4675 -8.3062 0.0 0
M  V30 69 O 1.1826 -5.4733 0.0 0
M  V30 70 O 3.713 -4.9232 0.0 0
M  V30 71 C 3.3004 -3.3829 0.0 0
M  V30 72 C 2.8879 -1.8427 0.0 0
M  V30 73 C 1.7877 -2.8604 0.0 0
M  V30 74 C 4.3181 -2.3103 0.0 0
M  V30 75 O 0.66 11.4416 0.0 0
M  V30 76 C 0.5775 10.0389 0.0 0
M  V30 77 O -0.7976 9.4063 0.0 0
M  V30 78 O 1.7877 9.4063 0.0 0
M  V30 79 C -2.1728 10.204 0.0 0
M  V30 80 C 2.9979 10.204 0.0 0
M  V30 81 O -2.2553 11.7717 0.0 0
M  V30 82 O -3.548 9.5714 0.0 0
M  V30 83 C 2.9154 11.7717 0.0 0
M  V30 84 C 4.2081 11.0016 0.0 0
M  V30 85 C 4.2081 9.5714 0.0 0
M  V30 86 C -4.9232 10.369 0.0 0
M  V30 87 C -6.2984 9.7364 0.0 0
M  V30 88 C -6.2984 11.1666 0.0 0
M  V30 89 C -5.0057 11.9367 0.0 0
M  V30 90 O 8.3612 -21.7832 0.0 0
M  V30 91 C 9.6814 -22.1407 0.0 0
M  V30 92 O 10.699 -21.0681 0.0 0
M  V30 93 N 9.9014 -23.4884 0.0 0
M  V30 94 C 10.2865 -19.5278 0.0 0
M  V30 95 C 8.8288 -24.5061 0.0 0
M  V30 96 C 11.1666 -24.011 0.0 0
M  V30 97 C 9.8739 -17.9876 0.0 0
M  V30 98 C 8.7737 -19.0053 0.0 0
M  V30 99 C 11.3041 -18.4552 0.0 0
M  V30 100 N 9.4613 -25.7162 0.0 0
M  V30 101 N 7.261 -24.2585 0.0 0
M  V30 102 C 12.3768 -23.2134 0.0 0
M  V30 103 C 10.9191 -25.4137 0.0 0
M  V30 104 C 6.2709 -25.3312 0.0 0
M  V30 105 C 6.6009 -22.8283 0.0 0
M  V30 106 C 13.587 -23.846 0.0 0
M  V30 107 C 12.2943 -21.6456 0.0 0
M  V30 108 C 11.9367 -26.2938 0.0 0
M  V30 109 O 6.7384 -26.5964 0.0 0
M  V30 110 O 4.7306 -25.0561 0.0 0
M  V30 111 O 5.0332 -22.5533 0.0 0
M  V30 112 O 7.3985 -21.5906 0.0 0
M  V30 113 C 14.7971 -23.0484 0.0 0
M  V30 114 C 13.5044 -20.848 0.0 0
M  V30 115 C 3.7405 -26.1288 0.0 0
M  V30 116 C 6.7384 -20.1604 0.0 0
M  V30 117 N 16.0073 -23.6809 0.0 0
M  V30 118 C 14.7146 -21.4806 0.0 0
M  V30 119 C 2.7504 -27.2015 0.0 0
M  V30 120 C 4.2081 -27.394 0.0 0
M  V30 121 C 2.2003 -25.8538 0.0 0
M  V30 122 C 6.0783 -18.7302 0.0 0
M  V30 123 C 5.1707 -19.8854 0.0 0
M  V30 124 C 7.5361 -18.8677 0.0 0
M  V30 125 O 12.9819 2.4203 0.0 0
M  V30 126 C 12.8994 1.0176 0.0 0
M  V30 127 O 14.1095 0.385 0.0 0
M  V30 128 N 11.5242 0.385 0.0 0
M  V30 129 C 15.3197 1.1826 0.0 0
M  V30 130 C 10.1489 1.1826 0.0 0
M  V30 131 C 16.5299 1.9802 0.0 0
M  V30 132 C 15.2372 2.7504 0.0 0
M  V30 133 C 16.5299 0.55 0.0 0
M  V30 134 N 10.0664 2.7504 0.0 0
M  V30 135 N 8.7737 0.55 0.0 0
M  V30 136 C 14.9622 -22.2232 0.0 0
M  V30 137 ? 15.6498 -20.903 0.0 0
M  V30 138 C 8.8012 -14.3021 0.0 0
M  V30 139 ? 9.4889 -12.9819 0.0 0
M  V30 140 C 7.9211 -6.3809 0.0 0
M  V30 141 ? 8.6087 -5.0607 0.0 0
M  V30 142 C 3.7405 0.22 0.0 0
M  V30 143 ? 4.4281 1.5402 0.0 0
M  V30 144 C 11.4416 -27.724 0.0 0
M  V30 145 H 13.642 -14.3021 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=3
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 2 6 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 9 11
M  V30 11 2 9 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 2 15 16
M  V30 15 1 16 17
M  V30 16 1 16 18
M  V30 17 2 18 19
M  V30 18 1 18 20
M  V30 19 1 19 21
M  V30 20 2 20 22
M  V30 21 1 21 23
M  V30 22 2 21 24
M  V30 23 1 23 25
M  V30 24 2 23 26
M  V30 25 1 25 27
M  V30 26 1 25 28
M  V30 27 1 26 29
M  V30 28 1 26 30
M  V30 29 1 27 31
M  V30 30 2 28 32
M  V30 31 1 28 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 33 36
M  V30 35 2 34 37
M  V30 36 1 34 38
M  V30 37 2 35 39
M  V30 38 1 35 40
M  V30 39 1 36 41
M  V30 40 1 36 42
M  V30 41 1 36 43
M  V30 42 1 38 44
M  V30 43 1 40 45
M  V30 44 1 44 46
M  V30 45 1 44 47
M  V30 46 1 44 48
M  V30 47 1 45 49
M  V30 48 1 45 50
M  V30 49 1 45 51
M  V30 50 2 52 53
M  V30 51 1 53 54
M  V30 52 1 53 55
M  V30 53 2 55 56
M  V30 54 1 55 57
M  V30 55 1 56 58
M  V30 56 2 57 59
M  V30 57 1 58 60
M  V30 58 2 58 61
M  V30 59 1 60 62
M  V30 60 2 60 63
M  V30 61 1 62 64
M  V30 62 1 62 65
M  V30 63 1 63 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 2 65 69
M  V30 67 1 65 70
M  V30 68 1 70 71
M  V30 69 1 71 72
M  V30 70 1 71 73
M  V30 71 1 71 74
M  V30 72 2 75 76
M  V30 73 1 76 77
M  V30 74 1 76 78
M  V30 75 1 77 79
M  V30 76 1 78 80
M  V30 77 2 79 81
M  V30 78 1 79 82
M  V30 79 1 80 83
M  V30 80 1 80 84
M  V30 81 1 80 85
M  V30 82 1 82 86
M  V30 83 1 86 87
M  V30 84 1 86 88
M  V30 85 1 86 89
M  V30 86 2 90 91
M  V30 87 1 91 92
M  V30 88 1 91 93
M  V30 89 1 92 94
M  V30 90 1 93 95
M  V30 91 1 93 96
M  V30 92 1 94 97
M  V30 93 1 94 98
M  V30 94 1 94 99
M  V30 95 2 95 100
M  V30 96 1 95 101
M  V30 97 1 96 102
M  V30 98 2 96 103
M  V30 99 1 101 104
M  V30 100 1 101 105
M  V30 101 2 102 106
M  V30 102 1 102 107
M  V30 103 1 103 108
M  V30 104 2 104 109
M  V30 105 1 104 110
M  V30 106 2 105 111
M  V30 107 1 105 112
M  V30 108 1 106 113
M  V30 109 2 107 114
M  V30 110 1 110 115
M  V30 111 1 112 116
M  V30 112 1 113 117
M  V30 113 2 113 118
M  V30 114 1 115 119
M  V30 115 1 115 120
M  V30 116 1 115 121
M  V30 117 1 116 122
M  V30 118 1 116 123
M  V30 119 1 116 124
M  V30 120 2 125 126
M  V30 121 1 126 127
M  V30 122 1 126 128
M  V30 123 1 127 129
M  V30 124 1 128 130
M  V30 125 1 129 131
M  V30 126 1 129 132
M  V30 127 1 129 133
M  V30 128 2 130 134
M  V30 129 1 130 135
M  V30 130 1 136 137
M  V30 131 1 138 139
M  V30 132 1 140 141
M  V30 133 1 142 143
M  V30 134 1 10 12
M  V30 135 1 22 24
M  V30 136 2 27 29
M  V30 137 1 59 61
M  V30 138 2 64 66
M  V30 139 1 100 103
M  V30 140 1 114 118
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00048001.cdx

>  <name>
US20220000118A1-20220106-C00028

>  <Row No>
173

$$$$
US20220000118A1-20220106-C00029
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 158 153 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.1053 -1.37 0.0 0 CFG=2
M  V30 3 C 1.089 -2.0023 0.0 0
M  V30 4 C -1.4754 -2.0023 0.0 0
M  V30 5 O 0.9836 -3.3723 0.0 0
M  V30 6 C 2.2833 -1.1943 0.0 0
M  V30 7 C 3.4777 -1.8267 0.0 0
M  V30 8 C 2.178 0.3864 0.0 0
M  V30 9 C 4.6721 -1.0187 0.0 0
M  V30 10 C 3.3723 1.2295 0.0 0
M  V30 11 N 5.8665 -1.651 0.0 0 CHG=1
M  V30 12 C 4.5667 0.562 0.0 0
M  V30 13 O 5.7611 -3.021 0.0 0
M  V30 14 O 7.0609 -0.843 0.0 0 CHG=-1
M  V30 15 O 10.9602 -25.5739 0.0 0
M  V30 16 N 10.8548 -23.9931 0.0 0 CHG=1
M  V30 17 O 12.0492 -23.1851 0.0 0 CHG=-1
M  V30 18 C 9.4848 -23.1851 0.0 0
M  V30 19 C 8.1148 -23.8175 0.0 0
M  V30 20 C 9.3794 -21.6043 0.0 0
M  V30 21 C 6.7447 -23.0095 0.0 0
M  V30 22 C 8.0094 -20.7612 0.0 0
M  V30 23 C 5.3747 -23.6418 0.0 0
M  V30 24 C 6.6393 -21.4287 0.0 0
M  V30 25 N 3.9344 -22.9744 0.0 0
M  V30 26 C 5.1288 -25.0118 0.0 0
M  V30 27 C 2.8454 -23.958 0.0 0
M  V30 28 C 3.5129 -21.4287 0.0 0
M  V30 29 N 3.5831 -25.2226 0.0 0
M  V30 30 C 6.1124 -25.8901 0.0 0
M  V30 31 N 1.2646 -23.7121 0.0 0
M  V30 32 O 2.0023 -20.8666 0.0 0
M  V30 33 O 4.4965 -20.3397 0.0 0
M  V30 34 C 0.2459 -24.7659 0.0 0
M  V30 35 C 0.5971 -22.2366 0.0 0
M  V30 36 C 4.0749 -18.794 0.0 0
M  V30 37 O 0.7377 -26.0306 0.0 0
M  V30 38 O -1.2997 -24.4849 0.0 0
M  V30 39 O -0.9836 -21.9556 0.0 0
M  V30 40 O 1.4051 -20.972 0.0 0
M  V30 41 C 3.6534 -17.2483 0.0 0
M  V30 42 C 2.5644 -18.2319 0.0 0
M  V30 43 C 5.0585 -17.705 0.0 0
M  V30 44 C -2.3185 -25.5388 0.0 0
M  V30 45 C 0.7377 -19.4966 0.0 0
M  V30 46 C -3.3372 -26.5927 0.0 0
M  V30 47 C -1.8267 -26.8034 0.0 0
M  V30 48 C -3.8641 -25.2577 0.0 0
M  V30 49 C 0.0702 -18.0212 0.0 0
M  V30 50 C -0.8079 -19.2155 0.0 0
M  V30 51 C 1.5456 -18.2319 0.0 0
M  V30 52 O 10.1171 -10.1171 0.0 0
M  V30 53 N 10.0117 -8.5363 0.0 0 CHG=1
M  V30 54 O 11.2061 -7.7283 0.0 0 CHG=-1
M  V30 55 C 8.6417 -7.7283 0.0 0
M  V30 56 C 7.2717 -8.3607 0.0 0
M  V30 57 C 8.5363 -6.1475 0.0 0
M  V30 58 C 5.9016 -7.5527 0.0 0
M  V30 59 C 7.1663 -5.3044 0.0 0
M  V30 60 C 4.5316 -8.185 0.0 0
M  V30 61 C 5.7962 -5.9719 0.0 0
M  V30 62 N 3.0913 -7.5176 0.0 0
M  V30 63 C 4.2857 -9.5551 0.0 0
M  V30 64 C 2.0023 -8.5012 0.0 0
M  V30 65 C 2.5292 -6.007 0.0 0
M  V30 66 N 2.74 -9.7658 0.0 0
M  V30 67 C 5.2693 -10.4333 0.0 0
M  V30 68 N 0.4566 -8.0796 0.0 0
M  V30 69 C 0.9836 -5.5855 0.0 0
M  V30 70 C -0.1053 -6.5691 0.0 0
M  V30 71 O 10.1171 -17.986 0.0 0
M  V30 72 N 10.0117 -16.4052 0.0 0 CHG=1
M  V30 73 O 11.2061 -15.5973 0.0 0 CHG=-1
M  V30 74 C 8.6417 -15.5973 0.0 0
M  V30 75 C 7.2717 -16.2296 0.0 0
M  V30 76 C 8.5363 -14.0164 0.0 0
M  V30 77 C 5.9016 -15.4216 0.0 0
M  V30 78 C 7.1663 -13.1733 0.0 0
M  V30 79 C 4.5316 -16.0539 0.0 0
M  V30 80 C 5.7962 -13.8408 0.0 0
M  V30 81 C 4.2857 -17.424 0.0 0
M  V30 82 C 3.0913 -15.3865 0.0 0
M  V30 83 N 2.74 -17.6347 0.0 0
M  V30 84 C 5.2693 -18.3022 0.0 0
M  V30 85 C 2.0023 -16.3701 0.0 0
M  V30 86 N 0.4215 -16.1242 0.0 0
M  V30 87 O 0.281 2.8103 0.0 0
M  V30 88 C 0.1756 1.4402 0.0 0
M  V30 89 O -1.1943 0.8079 0.0 0
M  V30 90 O 1.37 0.8079 0.0 0
M  V30 91 C -2.5644 1.6159 0.0 0
M  V30 92 C 2.5644 1.6159 0.0 0
M  V30 93 O -2.6698 3.1967 0.0 0
M  V30 94 O -3.9344 0.9836 0.0 0
M  V30 95 C 2.459 3.1967 0.0 0
M  V30 96 C 3.7588 2.4239 0.0 0
M  V30 97 C 3.7588 0.9836 0.0 0
M  V30 98 C -5.3044 1.7915 0.0 0
M  V30 99 C -6.6745 1.1592 0.0 0
M  V30 100 C -6.6745 2.5995 0.0 0
M  V30 101 C -5.4098 3.3723 0.0 0
M  V30 102 O 8.4309 -29.5084 0.0 0
M  V30 103 C 9.7658 -29.8597 0.0 0
M  V30 104 O 10.7494 -28.7707 0.0 0
M  V30 105 N 9.9766 -31.2297 0.0 0
M  V30 106 C 10.3279 -27.225 0.0 0
M  V30 107 C 8.8876 -32.2133 0.0 0
M  V30 108 C 11.2413 -31.7215 0.0 0
M  V30 109 C 9.9063 -25.6793 0.0 0
M  V30 110 C 8.8173 -26.6629 0.0 0
M  V30 111 C 11.3115 -26.136 0.0 0
M  V30 112 N 9.5199 -33.4077 0.0 0
M  V30 113 N 7.3068 -31.9674 0.0 0
M  V30 114 C 12.4356 -30.9135 0.0 0
M  V30 115 C 10.9953 -33.0915 0.0 0
M  V30 116 C 6.2881 -33.0213 0.0 0
M  V30 117 C 6.6393 -30.492 0.0 0
M  V30 118 C 13.63 -31.5459 0.0 0
M  V30 119 C 12.3303 -29.3327 0.0 0
M  V30 120 C 11.979 -33.9698 0.0 0
M  V30 121 O 6.7799 -34.2859 0.0 0
M  V30 122 O 4.7424 -32.7402 0.0 0
M  V30 123 O 5.0937 -30.2109 0.0 0
M  V30 124 O 7.4473 -29.2273 0.0 0
M  V30 125 C 14.8244 -30.7379 0.0 0
M  V30 126 C 13.5246 -28.4896 0.0 0
M  V30 127 C 3.7236 -33.7941 0.0 0
M  V30 128 C 6.7799 -27.7519 0.0 0
M  V30 129 N 16.0188 -31.3702 0.0 0
M  V30 130 C 14.719 -29.1571 0.0 0
M  V30 131 C 2.7049 -34.848 0.0 0
M  V30 132 C 4.2154 -35.0588 0.0 0
M  V30 133 C 2.178 -33.5131 0.0 0
M  V30 134 C 6.1124 -26.2765 0.0 0
M  V30 135 C 5.2342 -27.4709 0.0 0
M  V30 136 C 7.5878 -26.4873 0.0 0
M  V30 137 N 9.274 2.5292 0.0 0
M  V30 138 C 10.4684 1.8969 0.0 0
M  V30 139 C 7.904 1.8969 0.0 0
M  V30 140 N 10.363 0.5269 0.0 0
M  V30 141 N 11.6628 2.7049 0.0 0
M  V30 142 C 7.7986 0.5269 0.0 0
M  V30 143 C 8.993 -0.1053 0.0 0
M  V30 144 N 11.5223 -7.8689 0.0 0
M  V30 145 N 12.8923 -7.7635 0.0 0
M  V30 146 C 8.993 -22.2015 0.0 0
M  V30 147 ? 9.6956 -20.8666 0.0 0
M  V30 148 C 7.8689 -14.0516 0.0 0
M  V30 149 ? 8.5714 -12.7167 0.0 0
M  V30 150 C 3.6534 0.281 0.0 0
M  V30 151 ? 4.356 1.6159 0.0 0
M  V30 152 C 14.3326 -29.7894 0.0 0
M  V30 153 ? 15.0352 -28.4545 0.0 0
M  V30 154 C 7.8689 -6.4637 0.0 0
M  V30 155 ? 8.5714 -5.1288 0.0 0
M  V30 156 C 11.2413 -35.41 0.0 0
M  V30 157 H 13.4895 -23.3256 0.0 0
M  V30 158 H 14.6136 -7.8689 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=3
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 2 6 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 9 11
M  V30 11 2 9 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 2 15 16
M  V30 15 1 16 17
M  V30 16 1 16 18
M  V30 17 2 18 19
M  V30 18 1 18 20
M  V30 19 1 19 21
M  V30 20 2 20 22
M  V30 21 1 21 23
M  V30 22 2 21 24
M  V30 23 1 23 25
M  V30 24 2 23 26
M  V30 25 1 25 27
M  V30 26 1 25 28
M  V30 27 1 26 29
M  V30 28 1 26 30
M  V30 29 1 27 31
M  V30 30 2 28 32
M  V30 31 1 28 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 33 36
M  V30 35 2 34 37
M  V30 36 1 34 38
M  V30 37 2 35 39
M  V30 38 1 35 40
M  V30 39 1 36 41
M  V30 40 1 36 42
M  V30 41 1 36 43
M  V30 42 1 38 44
M  V30 43 1 40 45
M  V30 44 1 44 46
M  V30 45 1 44 47
M  V30 46 1 44 48
M  V30 47 1 45 49
M  V30 48 1 45 50
M  V30 49 1 45 51
M  V30 50 2 52 53
M  V30 51 1 53 54
M  V30 52 1 53 55
M  V30 53 2 55 56
M  V30 54 1 55 57
M  V30 55 1 56 58
M  V30 56 2 57 59
M  V30 57 1 58 60
M  V30 58 2 58 61
M  V30 59 1 60 62
M  V30 60 2 60 63
M  V30 61 1 62 64
M  V30 62 1 62 65
M  V30 63 1 63 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 2 65 69
M  V30 67 2 68 70
M  V30 68 2 71 72
M  V30 69 1 72 73
M  V30 70 1 72 74
M  V30 71 2 74 75
M  V30 72 1 74 76
M  V30 73 1 75 77
M  V30 74 2 76 78
M  V30 75 1 77 79
M  V30 76 2 77 80
M  V30 77 2 79 81
M  V30 78 1 79 82
M  V30 79 1 81 83
M  V30 80 1 81 84
M  V30 81 1 82 85
M  V30 82 1 85 86
M  V30 83 2 87 88
M  V30 84 1 88 89
M  V30 85 1 88 90
M  V30 86 1 89 91
M  V30 87 1 90 92
M  V30 88 2 91 93
M  V30 89 1 91 94
M  V30 90 1 92 95
M  V30 91 1 92 96
M  V30 92 1 92 97
M  V30 93 1 94 98
M  V30 94 1 98 99
M  V30 95 1 98 100
M  V30 96 1 98 101
M  V30 97 2 102 103
M  V30 98 1 103 104
M  V30 99 1 103 105
M  V30 100 1 104 106
M  V30 101 1 105 107
M  V30 102 1 105 108
M  V30 103 1 106 109
M  V30 104 1 106 110
M  V30 105 1 106 111
M  V30 106 2 107 112
M  V30 107 1 107 113
M  V30 108 1 108 114
M  V30 109 2 108 115
M  V30 110 1 113 116
M  V30 111 1 113 117
M  V30 112 2 114 118
M  V30 113 1 114 119
M  V30 114 1 115 120
M  V30 115 2 116 121
M  V30 116 1 116 122
M  V30 117 2 117 123
M  V30 118 1 117 124
M  V30 119 1 118 125
M  V30 120 2 119 126
M  V30 121 1 122 127
M  V30 122 1 124 128
M  V30 123 1 125 129
M  V30 124 2 125 130
M  V30 125 1 127 131
M  V30 126 1 127 132
M  V30 127 1 127 133
M  V30 128 1 128 134
M  V30 129 1 128 135
M  V30 130 1 128 136
M  V30 131 2 137 138
M  V30 132 1 137 139
M  V30 133 1 138 140
M  V30 134 1 138 141
M  V30 135 2 139 142
M  V30 136 2 140 143
M  V30 137 2 144 145
M  V30 138 1 146 147
M  V30 139 1 148 149
M  V30 140 1 150 151
M  V30 141 1 152 153
M  V30 142 1 154 155
M  V30 143 1 10 12
M  V30 144 1 22 24
M  V30 145 2 27 29
M  V30 146 1 59 61
M  V30 147 2 64 66
M  V30 148 1 69 70
M  V30 149 1 78 80
M  V30 150 2 83 85
M  V30 151 1 112 115
M  V30 152 1 126 130
M  V30 153 1 142 143
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00049001.cdx

>  <name>
US20220000118A1-20220106-C00029

>  <Row No>
174

$$$$
US20220000118A1-20220106-C00030
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 51 51 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 N -0.0482 -1.4471 0.0 0
M  V30 3 C 1.222 -2.1546 0.0 0
M  V30 4 C 1.1737 -3.6017 0.0 0
M  V30 5 C 2.4922 -1.3667 0.0 0
M  V30 6 C 2.444 -4.3092 0.0 0
M  V30 7 C 3.7625 -2.0742 0.0 0
M  V30 8 C 3.7143 -3.5213 0.0 0
M  V30 9 O 2.3154 -11.0625 0.0 0
M  V30 10 C 2.2671 -12.5096 0.0 0
M  V30 11 N 0.9165 -13.2171 0.0 0
M  V30 12 N 3.5374 -13.2171 0.0 0
M  V30 13 C -0.4341 -12.4292 0.0 0
M  V30 14 C 3.4892 -14.6643 0.0 0
M  V30 15 C -1.7848 -13.1367 0.0 0
M  V30 16 C -0.4823 -10.8856 0.0 0
M  V30 17 C 2.1385 -15.3717 0.0 0
M  V30 18 C 4.7594 -15.3717 0.0 0
M  V30 19 C -3.1354 -12.3488 0.0 0
M  V30 20 C -1.833 -10.0977 0.0 0
M  V30 21 C 2.0903 -16.8189 0.0 0
M  V30 22 C 4.7112 -16.8189 0.0 0
M  V30 23 C -4.4861 -13.0563 0.0 0
M  V30 24 C -3.1836 -10.8052 0.0 0
M  V30 25 C 3.3605 -17.5264 0.0 0
M  V30 26 C -4.6951 -14.5035 0.0 0
M  V30 27 C -5.901 -12.4132 0.0 0
M  V30 28 N -6.2066 -14.7768 0.0 0
M  V30 29 C -6.9623 -13.4905 0.0 0
M  V30 30 N -8.5059 -13.2814 0.0 0
M  V30 31 N -10.1621 -6.303 0.0 0
M  V30 32 C -10.9499 -4.9524 0.0 0
M  V30 33 C -8.7471 -5.9493 0.0 0
M  V30 34 N -10.0013 -3.7786 0.0 0
M  V30 35 N -12.4936 -4.7433 0.0 0
M  V30 36 C -8.6345 -4.4057 0.0 0
M  V30 37 C -10.355 -2.2671 0.0 0
M  V30 38 C -13.4422 -5.885 0.0 0
M  V30 39 C -13.1367 -3.3123 0.0 0
M  V30 40 C -7.3643 -3.6178 0.0 0
M  V30 41 C -6.094 -4.3253 0.0 0
M  V30 42 C -7.4125 -2.0742 0.0 0
M  V30 43 C -4.8237 -3.5374 0.0 0
M  V30 44 C -6.1422 -1.2863 0.0 0
M  V30 45 N -3.5535 -4.2449 0.0 0
M  V30 46 C -4.872 -1.9938 0.0 0
M  V30 47 C 4.3735 -16.2079 0.0 0
M  V30 48 C 5.8207 -16.1596 0.0 0
M  V30 49 C 3.2158 -2.8299 0.0 0
M  V30 50 ? 4.6951 -2.8138 0.0 0
M  V30 51 C -8.1039 -7.8466 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 2 3 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 2 6 8
M  V30 8 2 9 10
M  V30 9 1 10 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 1 12 14
M  V30 13 2 13 15
M  V30 14 1 13 16
M  V30 15 2 14 17
M  V30 16 1 14 18
M  V30 17 1 15 19
M  V30 18 2 16 20
M  V30 19 1 17 21
M  V30 20 2 18 22
M  V30 21 1 19 23
M  V30 22 2 19 24
M  V30 23 2 21 25
M  V30 24 2 23 26
M  V30 25 1 23 27
M  V30 26 1 26 28
M  V30 27 1 27 29
M  V30 28 1 29 30
M  V30 29 2 31 32
M  V30 30 1 31 33
M  V30 31 1 32 34
M  V30 32 1 32 35
M  V30 33 2 33 36
M  V30 34 1 34 37
M  V30 35 1 35 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 2 40 41
M  V30 39 1 40 42
M  V30 40 1 41 43
M  V30 41 2 42 44
M  V30 42 1 43 45
M  V30 43 2 43 46
M  V30 44 1 47 48
M  V30 45 1 49 50
M  V30 46 1 7 8
M  V30 47 1 20 24
M  V30 48 1 22 25
M  V30 49 2 28 29
M  V30 50 1 34 36
M  V30 51 1 44 46
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00050001.cdx

>  <name>
US20220000118A1-20220106-C00030

>  <Row No>
175

$$$$
US20220000118A1-20220106-C00031
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 67 68 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 N -0.0362 1.4999 0.0 0
M  V30 3 C -1.3427 2.2741 0.0 0
M  V30 4 C -2.6491 1.5725 0.0 0
M  V30 5 C -1.379 3.7741 0.0 0
M  V30 6 C -3.9556 2.3467 0.0 0
M  V30 7 C -2.6854 4.5483 0.0 0
M  V30 8 C -5.262 1.6451 0.0 0
M  V30 9 C -3.9919 3.8467 0.0 0
M  V30 10 N -6.6411 2.2862 0.0 0
M  V30 11 C -5.4556 0.2177 0.0 0
M  V30 12 C -7.6572 1.2338 0.0 0
M  V30 13 C -6.9919 3.762 0.0 0
M  V30 14 N -6.9314 -0.0483 0.0 0
M  V30 15 N -9.1572 1.4274 0.0 0
M  V30 16 C -10.0886 0.3145 0.0 0
M  V30 17 C -9.7862 2.8185 0.0 0
M  V30 18 O 5.3225 -2.9999 0.0 0
M  V30 19 C 5.2862 -4.4636 0.0 0
M  V30 20 N 3.9435 -5.1895 0.0 0
M  V30 21 N 6.5564 -5.1895 0.0 0
M  V30 22 C 2.6007 -4.3911 0.0 0
M  V30 23 C 6.5201 -6.6532 0.0 0
M  V30 24 C 1.258 -5.1169 0.0 0
M  V30 25 C 2.5645 -2.8427 0.0 0
M  V30 26 C 5.1774 -7.379 0.0 0
M  V30 27 C 7.7903 -7.379 0.0 0
M  V30 28 C -0.0846 -4.3185 0.0 0
M  V30 29 C 1.2217 -2.0443 0.0 0
M  V30 30 C 5.1411 -8.8427 0.0 0
M  V30 31 C 7.754 -8.8427 0.0 0
M  V30 32 C -1.4274 -5.0443 0.0 0
M  V30 33 C -0.1209 -2.7701 0.0 0
M  V30 34 C 6.4112 -9.5685 0.0 0
M  V30 35 C -1.6209 -6.508 0.0 0
M  V30 36 C -2.8548 -4.3911 0.0 0
M  V30 37 N -3.133 -6.7862 0.0 0
M  V30 38 C -3.9072 -5.4798 0.0 0
M  V30 39 N -5.4556 -5.2862 0.0 0
M  V30 40 N -7.3548 10.0644 0.0 0
M  V30 41 C -8.1532 11.4072 0.0 0
M  V30 42 C -5.9153 10.4273 0.0 0
M  V30 43 N -7.1733 12.5685 0.0 0
M  V30 44 N -9.7015 11.6007 0.0 0
M  V30 45 C -5.8064 11.9757 0.0 0
M  V30 46 C -7.5362 14.0806 0.0 0
M  V30 47 C -10.6693 10.4394 0.0 0
M  V30 48 C -10.3427 13.0281 0.0 0
M  V30 49 C -4.5362 12.7741 0.0 0
M  V30 50 C -3.2661 12.0483 0.0 0
M  V30 51 C -4.5725 14.3225 0.0 0
M  V30 52 C -1.9959 12.8467 0.0 0
M  V30 53 C -3.3024 15.1209 0.0 0
M  V30 54 N -0.7258 12.1209 0.0 0
M  V30 55 C -2.0322 14.3951 0.0 0
M  V30 56 N 3.387 4.8386 0.0 0
M  V30 57 C 4.6088 4.137 0.0 0
M  V30 58 C 4.5725 2.7096 0.0 0
M  V30 59 C 5.8306 4.9112 0.0 0
M  V30 60 C 5.7943 2.008 0.0 0
M  V30 61 C 7.0644 4.2096 0.0 0
M  V30 62 C 7.0161 2.7822 0.0 0
M  V30 63 C 6.6774 3.2903 0.0 0
M  V30 64 ? 8.129 3.3024 0.0 0
M  V30 65 C 7.3548 -8.3225 0.0 0
M  V30 66 ? 8.8548 -8.3104 0.0 0
M  V30 67 C -5.3225 8.6128 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 2 3 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 6 8
M  V30 8 2 6 9
M  V30 9 1 8 10
M  V30 10 2 8 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 15 16
M  V30 16 1 15 17
M  V30 17 2 18 19
M  V30 18 1 19 20
M  V30 19 1 19 21
M  V30 20 1 20 22
M  V30 21 1 21 23
M  V30 22 2 22 24
M  V30 23 1 22 25
M  V30 24 2 23 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 2 25 29
M  V30 28 1 26 30
M  V30 29 2 27 31
M  V30 30 1 28 32
M  V30 31 2 28 33
M  V30 32 2 30 34
M  V30 33 2 32 35
M  V30 34 1 32 36
M  V30 35 1 35 37
M  V30 36 1 36 38
M  V30 37 1 38 39
M  V30 38 2 40 41
M  V30 39 1 40 42
M  V30 40 1 41 43
M  V30 41 1 41 44
M  V30 42 2 42 45
M  V30 43 1 43 46
M  V30 44 1 44 47
M  V30 45 1 44 48
M  V30 46 1 45 49
M  V30 47 2 49 50
M  V30 48 1 49 51
M  V30 49 1 50 52
M  V30 50 2 51 53
M  V30 51 1 52 54
M  V30 52 2 52 55
M  V30 53 1 56 57
M  V30 54 2 57 58
M  V30 55 1 57 59
M  V30 56 1 58 60
M  V30 57 2 59 61
M  V30 58 2 60 62
M  V30 59 1 63 64
M  V30 60 1 65 66
M  V30 61 1 7 9
M  V30 62 2 12 14
M  V30 63 1 29 33
M  V30 64 1 31 34
M  V30 65 2 37 38
M  V30 66 1 43 45
M  V30 67 1 53 55
M  V30 68 1 61 62
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00051001.cdx

>  <name>
US20220000118A1-20220106-C00031

>  <Row No>
176

$$$$
US20220000118A1-20220106-C00032
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 34 35 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.3936 -0.4324 0.0 0
M  V30 3 O 2.4628 0.6006 0.0 0
M  V30 4 N 1.6699 -1.8621 0.0 0
M  V30 5 C 2.1144 2.1024 0.0 0
M  V30 6 C 0.6367 -2.9313 0.0 0
M  V30 7 C 3.0034 -2.4508 0.0 0
M  V30 8 C 1.766 3.6041 0.0 0
M  V30 9 C 0.6487 2.607 0.0 0
M  V30 10 C 3.1836 3.1356 0.0 0
M  V30 11 N 1.3575 -4.1928 0.0 0
M  V30 12 N -0.889 -2.7391 0.0 0
M  V30 13 C 4.2649 -1.6699 0.0 0
M  V30 14 C 2.8112 -3.9045 0.0 0
M  V30 15 C -1.802 -3.9165 0.0 0
M  V30 16 C -1.5497 -1.3335 0.0 0
M  V30 17 C 5.5263 -2.3907 0.0 0
M  V30 18 C 4.2288 -0.1321 0.0 0
M  V30 19 O -1.2134 -5.25 0.0 0
M  V30 20 O -3.3278 -3.7243 0.0 0
M  V30 21 O -3.0755 -1.1413 0.0 0
M  V30 22 O -0.7088 -0.084 0.0 0
M  V30 23 C 6.7878 -1.6098 0.0 0
M  V30 24 C 5.4903 0.6487 0.0 0
M  V30 25 C -4.2408 -4.9016 0.0 0
M  V30 26 C -1.3695 1.3215 0.0 0
M  V30 27 N 8.0492 -2.3306 0.0 0
M  V30 28 C 6.7517 -0.072 0.0 0
M  V30 29 C -5.1539 -6.079 0.0 0
M  V30 30 C -3.6522 -6.2352 0.0 0
M  V30 31 C -5.7666 -4.7094 0.0 0
M  V30 32 C -2.0303 2.7271 0.0 0
M  V30 33 C -2.8953 1.5137 0.0 0
M  V30 34 C -0.5286 2.5709 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 2 16 21
M  V30 21 1 16 22
M  V30 22 1 17 23
M  V30 23 2 18 24
M  V30 24 1 20 25
M  V30 25 1 22 26
M  V30 26 1 23 27
M  V30 27 2 23 28
M  V30 28 1 25 29
M  V30 29 1 25 30
M  V30 30 1 25 31
M  V30 31 1 26 32
M  V30 32 1 26 33
M  V30 33 1 26 34
M  V30 34 1 11 14
M  V30 35 1 24 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00053001.cdx

>  <name>
US20220000118A1-20220106-C00032

>  <Row No>
177

$$$$
US20220000118A1-20220106-C00033
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 N -0.0354 1.5123 0.0 0 CHG=1
M  V30 3 O 1.2051 2.2803 0.0 0 CHG=-1
M  V30 4 C -1.3469 2.2803 0.0 0
M  V30 5 C -2.6583 1.5595 0.0 0
M  V30 6 C -1.3823 3.7926 0.0 0
M  V30 7 C -3.9698 2.3275 0.0 0
M  V30 8 C -2.6938 4.5606 0.0 0
M  V30 9 C -5.2813 1.6186 0.0 0
M  V30 10 C -4.0053 3.8399 0.0 0
M  V30 11 N -6.6637 2.2685 0.0 0
M  V30 12 C -5.4703 0.189 0.0 0
M  V30 13 C -7.6798 1.2169 0.0 0
M  V30 14 C -7.0063 3.7453 0.0 0
M  V30 15 N -6.9472 -0.0827 0.0 0
M  V30 16 N -9.1803 1.4059 0.0 0
M  V30 17 O -8.4478 4.2416 0.0 0
M  V30 18 O -5.9548 4.7614 0.0 0
M  V30 19 C -6.2974 6.2383 0.0 0
M  V30 20 C -6.64 7.7152 0.0 0
M  V30 21 C -7.7388 6.7346 0.0 0
M  V30 22 C -5.2459 7.2544 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 2 7 10
M  V30 10 1 9 11
M  V30 11 2 9 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 1 14 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 19 21
M  V30 21 1 19 22
M  V30 22 1 8 10
M  V30 23 2 13 15
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00054001.cdx

>  <name>
US20220000118A1-20220106-C00033

>  <Row No>
178

$$$$
US20220000118A1-20220106-C00034
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 36 37 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 N -0.0355 1.5168 0.0 0 CHG=1
M  V30 3 O 1.2087 2.2753 0.0 0 CHG=-1
M  V30 4 C -1.3509 2.2753 0.0 0
M  V30 5 C -2.6663 1.5642 0.0 0
M  V30 6 C -1.3865 3.7922 0.0 0
M  V30 7 C -3.9818 2.3227 0.0 0
M  V30 8 C -2.7019 4.5624 0.0 0
M  V30 9 C -5.2972 1.6116 0.0 0
M  V30 10 C -4.0173 3.8396 0.0 0
M  V30 11 N -6.6837 2.2634 0.0 0
M  V30 12 C -5.4868 0.1777 0.0 0
M  V30 13 C -7.7029 1.2087 0.0 0
M  V30 14 C -7.0274 3.7448 0.0 0
M  V30 15 N -6.9681 -0.0948 0.0 0
M  V30 16 N -9.2079 1.3983 0.0 0
M  V30 17 O -8.4732 4.2425 0.0 0
M  V30 18 O -5.9727 4.7639 0.0 0
M  V30 19 C -10.1085 0.237 0.0 0
M  V30 20 C -9.8597 2.7849 0.0 0
M  V30 21 C -6.3163 6.2452 0.0 0
M  V30 22 O -9.5279 -1.0784 0.0 0
M  V30 23 O -11.6136 0.4266 0.0 0
M  V30 24 O -11.3647 2.9745 0.0 0
M  V30 25 O -9.0301 4.0173 0.0 0
M  V30 26 C -6.66 7.7266 0.0 0
M  V30 27 C -7.7621 6.743 0.0 0
M  V30 28 C -5.2616 7.2644 0.0 0
M  V30 29 C -12.5142 -0.7347 0.0 0
M  V30 30 C -9.6819 5.4038 0.0 0
M  V30 31 C -13.4149 -1.8961 0.0 0
M  V30 32 C -11.9335 -2.0501 0.0 0
M  V30 33 C -14.0193 -0.5451 0.0 0
M  V30 34 C -10.3337 6.7904 0.0 0
M  V30 35 C -11.187 5.5935 0.0 0
M  V30 36 C -8.8524 6.6363 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 2 7 10
M  V30 10 1 9 11
M  V30 11 2 9 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 1 14 18
M  V30 18 1 16 19
M  V30 19 1 16 20
M  V30 20 1 18 21
M  V30 21 2 19 22
M  V30 22 1 19 23
M  V30 23 2 20 24
M  V30 24 1 20 25
M  V30 25 1 21 26
M  V30 26 1 21 27
M  V30 27 1 21 28
M  V30 28 1 23 29
M  V30 29 1 25 30
M  V30 30 1 29 31
M  V30 31 1 29 32
M  V30 32 1 29 33
M  V30 33 1 30 34
M  V30 34 1 30 35
M  V30 35 1 30 36
M  V30 36 1 8 10
M  V30 37 2 13 15
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00055001.cdx

>  <name>
US20220000118A1-20220106-C00034

>  <Row No>
179

$$$$
US20220000118A1-20220106-C00035
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 34 35 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.3936 -0.4324 0.0 0
M  V30 3 O 2.4628 0.6006 0.0 0
M  V30 4 N 1.6699 -1.8621 0.0 0
M  V30 5 C 2.1144 2.1024 0.0 0
M  V30 6 C 0.6367 -2.9313 0.0 0
M  V30 7 C 3.0034 -2.4508 0.0 0
M  V30 8 C 1.766 3.6041 0.0 0
M  V30 9 C 0.6487 2.607 0.0 0
M  V30 10 C 3.1836 3.1356 0.0 0
M  V30 11 N 1.3575 -4.1928 0.0 0
M  V30 12 N -0.889 -2.7391 0.0 0
M  V30 13 C 4.2649 -1.6699 0.0 0
M  V30 14 C 2.8112 -3.9045 0.0 0
M  V30 15 C -1.5497 -1.3335 0.0 0
M  V30 16 C -1.802 -3.9165 0.0 0
M  V30 17 C 5.5263 -2.3907 0.0 0
M  V30 18 C 4.2288 -0.1321 0.0 0
M  V30 19 O -3.0755 -1.1413 0.0 0
M  V30 20 O -0.7088 -0.084 0.0 0
M  V30 21 O -1.2134 -5.25 0.0 0
M  V30 22 O -3.3278 -3.7243 0.0 0
M  V30 23 C 6.7878 -1.6098 0.0 0
M  V30 24 C 5.4903 0.6487 0.0 0
M  V30 25 C -1.3695 1.3215 0.0 0
M  V30 26 C -4.2408 -4.9016 0.0 0
M  V30 27 N 8.0492 -2.3306 0.0 0
M  V30 28 C 6.7517 -0.072 0.0 0
M  V30 29 C -2.0303 2.7271 0.0 0
M  V30 30 C -2.8953 1.5137 0.0 0
M  V30 31 C -0.5286 2.5709 0.0 0
M  V30 32 C -5.1539 -6.079 0.0 0
M  V30 33 C -3.6522 -6.2352 0.0 0
M  V30 34 C -5.7666 -4.7094 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 2 16 21
M  V30 21 1 16 22
M  V30 22 1 17 23
M  V30 23 2 18 24
M  V30 24 1 20 25
M  V30 25 1 22 26
M  V30 26 1 23 27
M  V30 27 2 23 28
M  V30 28 1 25 29
M  V30 29 1 25 30
M  V30 30 1 25 31
M  V30 31 1 26 32
M  V30 32 1 26 33
M  V30 33 1 26 34
M  V30 34 1 11 14
M  V30 35 1 24 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00056001.cdx

>  <name>
US20220000118A1-20220106-C00035

>  <Row No>
180

$$$$
US20220000118A1-20220106-C00036
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 35 36 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.3952 -0.4329 0.0 0
M  V30 3 O 2.4656 0.6013 0.0 0
M  V30 4 N 1.6718 -1.8643 0.0 0
M  V30 5 C 2.1168 2.1048 0.0 0
M  V30 6 C 0.6374 -2.9347 0.0 0
M  V30 7 C 3.0069 -2.4536 0.0 0
M  V30 8 C 1.768 3.6083 0.0 0
M  V30 9 C 0.6494 2.61 0.0 0
M  V30 10 C 3.1873 3.1392 0.0 0
M  V30 11 N 1.3591 -4.1976 0.0 0
M  V30 12 N -0.89 -2.7423 0.0 0
M  V30 13 C 4.2698 -1.6718 0.0 0
M  V30 14 C 2.8144 -3.909 0.0 0
M  V30 15 C -1.5515 -1.335 0.0 0
M  V30 16 C -1.8041 -3.921 0.0 0
M  V30 17 C 5.5327 -2.3935 0.0 0
M  V30 18 C 4.2337 -0.1323 0.0 0
M  V30 19 C 3.8849 -4.8712 0.0 0
M  V30 20 O -3.0791 -1.1426 0.0 0
M  V30 21 O -0.7096 -0.0841 0.0 0
M  V30 22 O -1.2148 -5.2561 0.0 0
M  V30 23 O -3.3316 -3.7286 0.0 0
M  V30 24 C 6.7956 -1.6117 0.0 0
M  V30 25 C 5.4966 0.6494 0.0 0
M  V30 26 C -1.3711 1.323 0.0 0
M  V30 27 C -4.2457 -4.9073 0.0 0
M  V30 28 N 8.0585 -2.3333 0.0 0
M  V30 29 C 6.7595 -0.0721 0.0 0
M  V30 30 C -2.0326 2.7302 0.0 0
M  V30 31 C -2.8986 1.5154 0.0 0
M  V30 32 C -0.5292 2.5739 0.0 0
M  V30 33 C -5.1599 -6.086 0.0 0
M  V30 34 C -3.6564 -6.2424 0.0 0
M  V30 35 C -5.7733 -4.7148 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 1 14 19
M  V30 19 2 15 20
M  V30 20 1 15 21
M  V30 21 2 16 22
M  V30 22 1 16 23
M  V30 23 1 17 24
M  V30 24 2 18 25
M  V30 25 1 21 26
M  V30 26 1 23 27
M  V30 27 1 24 28
M  V30 28 2 24 29
M  V30 29 1 26 30
M  V30 30 1 26 31
M  V30 31 1 26 32
M  V30 32 1 27 33
M  V30 33 1 27 34
M  V30 34 1 27 35
M  V30 35 1 11 14
M  V30 36 1 25 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00057001.cdx

>  <name>
US20220000118A1-20220106-C00036

>  <Row No>
181

$$$$
US20220000118A1-20220106-C00037
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 14 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.0364 -1.4808 0.0 0 CFG=2
M  V30 3 C 1.238 -2.2212 0.0 0
M  V30 4 C -1.3837 -2.2212 0.0 0
M  V30 5 O 1.2016 -3.7021 0.0 0
M  V30 6 C 2.5125 -1.4201 0.0 0
M  V30 7 C 3.787 -2.1605 0.0 0
M  V30 8 C 2.4761 0.1335 0.0 0
M  V30 9 C 5.0615 -1.3715 0.0 0
M  V30 10 C 3.7506 0.9346 0.0 0
M  V30 11 N 6.336 -2.112 0.0 0 CHG=1
M  V30 12 C 5.0251 0.182 0.0 0
M  V30 13 O 6.2996 -3.5928 0.0 0
M  V30 14 O 7.6105 -1.323 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=3
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 2 6 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 9 11
M  V30 11 2 9 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 1 10 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00058001.cdx

>  <name>
US20220000118A1-20220106-C00037

>  <Row No>
182

$$$$
US20220000118A1-20220106-C00038
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 O 10.5656 -0.7614 0.0 0
M  V30 3 N 9.233 -1.4515 0.0 0 CHG=1
M  V30 4 O 9.1616 -2.9031 0.0 0 CHG=-1
M  V30 5 C 7.9242 -0.6544 0.0 0
M  V30 6 C 6.6035 -1.3801 0.0 0
M  V30 7 C 7.8885 0.8685 0.0 0
M  V30 8 C 5.2828 -0.6068 0.0 0
M  V30 9 C 6.5678 1.6419 0.0 0
M  V30 10 C 3.974 -1.3445 0.0 0
M  V30 11 C 5.2471 0.9161 0.0 0
M  V30 12 N 2.5819 -0.69 0.0 0
M  V30 13 C 3.7836 -2.7841 0.0 0
M  V30 14 C 1.5586 -1.749 0.0 0
M  V30 15 N 2.2963 -3.0578 0.0 0
M  V30 16 C 4.8425 -3.736 0.0 0
M  V30 17 N 0.0356 -1.7133 0.0 0
M  V30 18 C 1.5229 -4.3071 0.0 0
M  V30 19 C -0.7376 -2.9626 0.0 0
M  V30 20 C 0.0 -4.2714 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 2 3
M  V30 2 1 3 4
M  V30 3 1 3 5
M  V30 4 2 5 6
M  V30 5 1 5 7
M  V30 6 1 6 8
M  V30 7 2 7 9
M  V30 8 1 8 10
M  V30 9 2 8 11
M  V30 10 1 10 12
M  V30 11 2 10 13
M  V30 12 2 12 14
M  V30 13 1 13 15
M  V30 14 1 13 16
M  V30 15 1 14 17
M  V30 16 1 15 18
M  V30 17 2 17 19
M  V30 18 2 18 20
M  V30 19 1 9 11
M  V30 20 1 14 15
M  V30 21 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00059001.cdx

>  <name>
US20220000118A1-20220106-C00038

>  <Row No>
183

$$$$
US20220000118A1-20220106-C00039
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 N -1.3323 -0.6899 0.0 0 CHG=1
M  V30 3 O -1.4036 -2.1412 0.0 0 CHG=-1
M  V30 4 C -2.6289 0.107 0.0 0
M  V30 5 C -3.9493 -0.6066 0.0 0
M  V30 6 C -2.6646 1.6297 0.0 0
M  V30 7 C -5.2697 0.1665 0.0 0
M  V30 8 C -3.985 2.4029 0.0 0
M  V30 9 C -6.5782 -0.559 0.0 0
M  V30 10 C -5.3054 1.6891 0.0 0
M  V30 11 N -7.97 0.0951 0.0 0
M  V30 12 C -6.7686 -1.9984 0.0 0
M  V30 13 C -8.9931 -0.9635 0.0 0
M  V30 14 N -8.2555 -2.272 0.0 0
M  V30 15 C -5.7218 -2.962 0.0 0
M  V30 16 N -10.5038 -0.7851 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 2 7 10
M  V30 10 1 9 11
M  V30 11 2 9 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 8 10
M  V30 17 2 13 14
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00060001.cdx

>  <name>
US20220000118A1-20220106-C00039

>  <Row No>
184

$$$$
US20220000118A1-20220106-C00040
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 37 38 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 N -1.3416 -0.6767 0.0 0 CHG=1
M  V30 3 O -1.4366 -2.1252 0.0 0 CHG=-1
M  V30 4 C -2.6595 0.0831 0.0 0
M  V30 5 C -3.9774 -0.6292 0.0 0
M  V30 6 C -2.6951 1.6028 0.0 0
M  V30 7 C -5.2953 0.1306 0.0 0
M  V30 8 C -4.013 2.3746 0.0 0
M  V30 9 C -6.6132 -0.5817 0.0 0
M  V30 10 C -5.331 1.6503 0.0 0
M  V30 11 N -8.0024 0.0712 0.0 0
M  V30 12 C -6.8032 -2.0184 0.0 0
M  V30 13 C -9.0235 -0.9854 0.0 0
M  V30 14 C -8.3467 1.5553 0.0 0
M  V30 15 N -8.2873 -2.2915 0.0 0
M  V30 16 C -5.7465 -2.9682 0.0 0
M  V30 17 N -10.5314 -0.7954 0.0 0
M  V30 18 O -9.7952 2.054 0.0 0
M  V30 19 O -7.29 2.5764 0.0 0
M  V30 20 C -11.1844 0.5936 0.0 0
M  V30 21 C -11.4337 -1.959 0.0 0
M  V30 22 C -7.6343 4.0605 0.0 0
M  V30 23 O -12.6923 0.7836 0.0 0
M  V30 24 O -10.3533 1.8284 0.0 0
M  V30 25 O -10.8519 -3.2769 0.0 0
M  V30 26 O -12.9416 -1.769 0.0 0
M  V30 27 C -7.9786 5.5447 0.0 0
M  V30 28 C -9.0828 4.5592 0.0 0
M  V30 29 C -6.5776 5.0816 0.0 0
M  V30 30 C -11.0063 3.2176 0.0 0
M  V30 31 C -13.8439 -2.9326 0.0 0
M  V30 32 C -11.6593 4.6067 0.0 0
M  V30 33 C -12.5142 3.4075 0.0 0
M  V30 34 C -10.1752 4.4523 0.0 0
M  V30 35 C -14.7463 -4.0962 0.0 0
M  V30 36 C -13.2622 -4.2505 0.0 0
M  V30 37 C -15.3518 -2.7426 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 2 7 10
M  V30 10 1 9 11
M  V30 11 2 9 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 2 14 18
M  V30 18 1 14 19
M  V30 19 1 17 20
M  V30 20 1 17 21
M  V30 21 1 19 22
M  V30 22 2 20 23
M  V30 23 1 20 24
M  V30 24 2 21 25
M  V30 25 1 21 26
M  V30 26 1 22 27
M  V30 27 1 22 28
M  V30 28 1 22 29
M  V30 29 1 24 30
M  V30 30 1 26 31
M  V30 31 1 30 32
M  V30 32 1 30 33
M  V30 33 1 30 34
M  V30 34 1 31 35
M  V30 35 1 31 36
M  V30 36 1 31 37
M  V30 37 1 8 10
M  V30 38 2 13 15
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00061001.cdx

>  <name>
US20220000118A1-20220106-C00040

>  <Row No>
185

$$$$
US20220000118A1-20220106-C00041
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 35 36 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.3956 -0.4331 0.0 0
M  V30 3 O 2.4665 0.6015 0.0 0
M  V30 4 N 1.6724 -1.8649 0.0 0
M  V30 5 C 2.1176 2.1055 0.0 0
M  V30 6 C 0.6376 -2.9357 0.0 0
M  V30 7 C 3.0079 -2.4545 0.0 0
M  V30 8 C 1.7686 3.6095 0.0 0
M  V30 9 C 0.6497 2.6109 0.0 0
M  V30 10 C 3.1884 3.1403 0.0 0
M  V30 11 N 1.3596 -4.1991 0.0 0
M  V30 12 N -0.8903 -2.7432 0.0 0
M  V30 13 C 4.2713 -1.6844 0.0 0
M  V30 14 C 2.8154 -3.9103 0.0 0
M  V30 15 C -1.8047 -3.9223 0.0 0
M  V30 16 C -1.5521 -1.3355 0.0 0
M  V30 17 C 5.5346 -2.4063 0.0 0
M  V30 18 C 4.2352 -0.1443 0.0 0
M  V30 19 C 3.8862 -4.8729 0.0 0
M  V30 20 O -1.2152 -5.2579 0.0 0
M  V30 21 O -3.3328 -3.7298 0.0 0
M  V30 22 O -3.0801 -1.143 0.0 0
M  V30 23 O -0.7098 -0.0842 0.0 0
M  V30 24 C 6.798 -1.6243 0.0 0
M  V30 25 C 5.4985 0.6256 0.0 0
M  V30 26 C -4.2472 -4.909 0.0 0
M  V30 27 C -1.3716 1.3235 0.0 0
M  V30 28 N 8.0613 -2.3462 0.0 0
M  V30 29 C 6.7619 -0.0842 0.0 0
M  V30 30 C -5.1616 -6.0881 0.0 0
M  V30 31 C -3.6576 -6.2445 0.0 0
M  V30 32 C -5.7753 -4.7164 0.0 0
M  V30 33 C -2.0333 2.7312 0.0 0
M  V30 34 C -2.8996 1.516 0.0 0
M  V30 35 C -0.5294 2.5748 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 1 14 19
M  V30 19 2 15 20
M  V30 20 1 15 21
M  V30 21 2 16 22
M  V30 22 1 16 23
M  V30 23 1 17 24
M  V30 24 2 18 25
M  V30 25 1 21 26
M  V30 26 1 23 27
M  V30 27 1 24 28
M  V30 28 2 24 29
M  V30 29 1 26 30
M  V30 30 1 26 31
M  V30 31 1 26 32
M  V30 32 1 27 33
M  V30 33 1 27 34
M  V30 34 1 27 35
M  V30 35 1 11 14
M  V30 36 1 25 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00062001.cdx

>  <name>
US20220000118A1-20220106-C00041

>  <Row No>
186

$$$$
US20220000118A1-20220106-C00042
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 35 36 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -1.3215 -0.7079 0.0 0
M  V30 3 C -1.3569 -2.1593 0.0 0
M  V30 4 C -2.6431 0.0589 0.0 0
M  V30 5 N -0.1061 -2.8673 0.0 0
M  V30 6 C -2.6785 -2.8673 0.0 0
M  V30 7 C -3.9647 -0.6489 0.0 0
M  V30 8 C -4.0001 -2.1003 0.0 0
M  V30 9 C -5.3217 -2.8083 0.0 0
M  V30 10 N -6.714 -2.1593 0.0 0
M  V30 11 C -5.5105 -4.2479 0.0 0
M  V30 12 C -7.7406 -3.2213 0.0 0
M  V30 13 C -7.0562 -0.6725 0.0 0
M  V30 14 N -6.9972 -4.5193 0.0 0
M  V30 15 N -9.251 -3.0325 0.0 0
M  V30 16 O -8.5076 -0.1769 0.0 0
M  V30 17 O -5.9943 0.3539 0.0 0
M  V30 18 C -9.9 -1.6401 0.0 0
M  V30 19 C -10.1596 -4.2007 0.0 0
M  V30 20 C -6.3364 1.8407 0.0 0
M  V30 21 O -11.4104 -1.4513 0.0 0
M  V30 22 O -9.0622 -0.4011 0.0 0
M  V30 23 O -9.5814 -5.5223 0.0 0
M  V30 24 O -11.67 -4.0119 0.0 0
M  V30 25 C -6.6786 3.3275 0.0 0
M  V30 26 C -7.7878 2.3363 0.0 0
M  V30 27 C -5.2745 2.8673 0.0 0
M  V30 28 C -9.7112 0.9911 0.0 0
M  V30 29 C -12.5785 -5.1801 0.0 0
M  V30 30 C -10.3602 2.3835 0.0 0
M  V30 31 C -11.2216 1.1799 0.0 0
M  V30 32 C -8.8734 2.2301 0.0 0
M  V30 33 C -13.4871 -6.3482 0.0 0
M  V30 34 C -12.0004 -6.5016 0.0 0
M  V30 35 C -14.0889 -4.9913 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 2 9 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 2 13 16
M  V30 16 1 13 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 2 18 21
M  V30 21 1 18 22
M  V30 22 2 19 23
M  V30 23 1 19 24
M  V30 24 1 20 25
M  V30 25 1 20 26
M  V30 26 1 20 27
M  V30 27 1 22 28
M  V30 28 1 24 29
M  V30 29 1 28 30
M  V30 30 1 28 31
M  V30 31 1 28 32
M  V30 32 1 29 33
M  V30 33 1 29 34
M  V30 34 1 29 35
M  V30 35 1 7 8
M  V30 36 2 12 14
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00063001.cdx

>  <name>
US20220000118A1-20220106-C00042

>  <Row No>
187

$$$$
US20220000118A1-20220106-C00043
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 14 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.0365 -1.4866 0.0 0
M  V30 3 C 1.2429 -2.2177 0.0 0
M  V30 4 O 1.2063 -3.7043 0.0 0
M  V30 5 C 2.5223 -1.4256 0.0 0
M  V30 6 C 3.8018 -2.1568 0.0 0
M  V30 7 C 2.4858 0.134 0.0 0
M  V30 8 C 5.0813 -1.3647 0.0 0
M  V30 9 C 3.7652 0.926 0.0 0
M  V30 10 N 6.3607 -2.0958 0.0 0 CHG=1
M  V30 11 C 5.0447 0.1949 0.0 0
M  V30 12 O 6.3242 -3.5825 0.0 0
M  V30 13 O 7.6402 -1.3038 0.0 0 CHG=-1
M  V30 14 F 6.3242 0.987 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 2 3 4
M  V30 4 1 3 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 8 10
M  V30 10 2 8 11
M  V30 11 2 10 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 9 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00064001.cdx

>  <name>
US20220000118A1-20220106-C00043

>  <Row No>
188

$$$$
US20220000118A1-20220106-C00044
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -1.3233 -0.7207 0.0 0
M  V30 3 C -1.3587 -2.174 0.0 0
M  V30 4 C -2.6466 0.059 0.0 0
M  V30 5 N -0.1063 -2.8947 0.0 0 CHG=1
M  V30 6 C -2.6821 -2.8947 0.0 0
M  V30 7 C -3.97 -0.6616 0.0 0
M  V30 8 O -0.1417 -4.3481 0.0 0
M  V30 9 O 1.1461 -2.1149 0.0 0 CHG=-1
M  V30 10 C -4.0054 -2.1149 0.0 0
M  V30 11 C -5.3287 -2.8357 0.0 0
M  V30 12 N -6.723 -2.1858 0.0 0
M  V30 13 C -5.5178 -4.2772 0.0 0
M  V30 14 C -7.7509 -3.2492 0.0 0
M  V30 15 C -7.0656 -0.6971 0.0 0
M  V30 16 N -7.0065 -4.5489 0.0 0
M  V30 17 N -9.2633 -3.0602 0.0 0
M  V30 18 O -8.5189 -0.2008 0.0 0
M  V30 19 O -6.0022 0.3308 0.0 0
M  V30 20 C -6.3449 1.8195 0.0 0
M  V30 21 C -6.6875 3.3083 0.0 0
M  V30 22 C -7.7982 2.3158 0.0 0
M  V30 23 C -5.2815 2.8475 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 2 11 13
M  V30 13 1 12 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 20 22
M  V30 22 1 20 23
M  V30 23 1 7 10
M  V30 24 2 14 16
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00065001.cdx

>  <name>
US20220000118A1-20220106-C00044

>  <Row No>
189

$$$$
US20220000118A1-20220106-C00045
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 37 38 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -1.3234 -0.7089 0.0 0
M  V30 3 C -1.3589 -2.1624 0.0 0
M  V30 4 C -2.6469 0.059 0.0 0
M  V30 5 N -0.1063 -2.8714 0.0 0 CHG=1
M  V30 6 C -2.6823 -2.8714 0.0 0
M  V30 7 C -3.9703 -0.6499 0.0 0
M  V30 8 O -0.1417 -4.3248 0.0 0
M  V30 9 O 1.1462 -2.1033 0.0 0 CHG=-1
M  V30 10 C -4.0058 -2.1033 0.0 0
M  V30 11 C -5.3292 -2.8123 0.0 0
M  V30 12 N -6.7236 -2.1624 0.0 0
M  V30 13 C -5.5183 -4.2539 0.0 0
M  V30 14 C -7.7516 -3.2259 0.0 0
M  V30 15 C -7.0663 -0.6735 0.0 0
M  V30 16 N -7.0072 -4.5257 0.0 0
M  V30 17 N -9.2642 -3.0368 0.0 0
M  V30 18 O -8.5197 -0.1772 0.0 0
M  V30 19 O -6.0028 0.3544 0.0 0
M  V30 20 C -9.9141 -1.6425 0.0 0
M  V30 21 C -10.174 -4.2067 0.0 0
M  V30 22 C -6.3455 1.8433 0.0 0
M  V30 23 O -11.4266 -1.4534 0.0 0
M  V30 24 O -9.0751 -0.4017 0.0 0
M  V30 25 O -9.595 -5.5301 0.0 0
M  V30 26 O -11.6866 -4.0176 0.0 0
M  V30 27 C -6.6881 3.3322 0.0 0
M  V30 28 C -7.7989 2.3396 0.0 0
M  V30 29 C -5.282 2.8714 0.0 0
M  V30 30 C -9.725 0.9925 0.0 0
M  V30 31 C -12.5964 -5.1874 0.0 0
M  V30 32 C -10.3749 2.3869 0.0 0
M  V30 33 C -11.2375 1.1816 0.0 0
M  V30 34 C -8.886 2.2333 0.0 0
M  V30 35 C -13.5063 -6.3573 0.0 0
M  V30 36 C -12.0174 -6.5109 0.0 0
M  V30 37 C -14.109 -4.9984 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 2 11 13
M  V30 13 1 12 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 17 21
M  V30 21 1 19 22
M  V30 22 2 20 23
M  V30 23 1 20 24
M  V30 24 2 21 25
M  V30 25 1 21 26
M  V30 26 1 22 27
M  V30 27 1 22 28
M  V30 28 1 22 29
M  V30 29 1 24 30
M  V30 30 1 26 31
M  V30 31 1 30 32
M  V30 32 1 30 33
M  V30 33 1 30 34
M  V30 34 1 31 35
M  V30 35 1 31 36
M  V30 36 1 31 37
M  V30 37 1 7 10
M  V30 38 2 14 16
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00066001.cdx

>  <name>
US20220000118A1-20220106-C00045

>  <Row No>
190

$$$$
US20220000118A1-20220106-C00046
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 35 36 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -1.3215 -0.7079 0.0 0
M  V30 3 C -1.3569 -2.1593 0.0 0
M  V30 4 C -2.6431 0.0589 0.0 0
M  V30 5 N -0.1061 -2.8673 0.0 0
M  V30 6 C -2.6785 -2.8673 0.0 0
M  V30 7 C -3.9647 -0.6489 0.0 0
M  V30 8 C -4.0001 -2.1003 0.0 0
M  V30 9 C -5.3217 -2.8083 0.0 0
M  V30 10 N -6.714 -2.1593 0.0 0
M  V30 11 C -5.5105 -4.2479 0.0 0
M  V30 12 C -7.7406 -3.2213 0.0 0
M  V30 13 C -7.0562 -0.6725 0.0 0
M  V30 14 N -6.9972 -4.5193 0.0 0
M  V30 15 N -9.251 -3.0325 0.0 0
M  V30 16 O -8.5076 -0.1769 0.0 0
M  V30 17 O -5.9943 0.3539 0.0 0
M  V30 18 C -10.1596 -4.2007 0.0 0
M  V30 19 C -9.9 -1.6401 0.0 0
M  V30 20 C -6.3364 1.8407 0.0 0
M  V30 21 O -9.5814 -5.5223 0.0 0
M  V30 22 O -11.67 -4.0119 0.0 0
M  V30 23 O -11.4104 -1.4513 0.0 0
M  V30 24 O -9.0622 -0.4011 0.0 0
M  V30 25 C -6.6786 3.3275 0.0 0
M  V30 26 C -7.7878 2.3363 0.0 0
M  V30 27 C -5.2745 2.8673 0.0 0
M  V30 28 C -12.5785 -5.1801 0.0 0
M  V30 29 C -9.7112 0.9911 0.0 0
M  V30 30 C -13.4871 -6.3482 0.0 0
M  V30 31 C -12.0004 -6.5016 0.0 0
M  V30 32 C -14.0889 -4.9913 0.0 0
M  V30 33 C -10.3602 2.3835 0.0 0
M  V30 34 C -11.2216 1.1799 0.0 0
M  V30 35 C -8.8734 2.2301 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 2 9 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 2 13 16
M  V30 16 1 13 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 2 18 21
M  V30 21 1 18 22
M  V30 22 2 19 23
M  V30 23 1 19 24
M  V30 24 1 20 25
M  V30 25 1 20 26
M  V30 26 1 20 27
M  V30 27 1 22 28
M  V30 28 1 24 29
M  V30 29 1 28 30
M  V30 30 1 28 31
M  V30 31 1 28 32
M  V30 32 1 29 33
M  V30 33 1 29 34
M  V30 34 1 29 35
M  V30 35 1 7 8
M  V30 36 2 12 14
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00067001.cdx

>  <name>
US20220000118A1-20220106-C00046

>  <Row No>
191

$$$$
US20220000118A1-20220106-C00047
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 36 37 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.3935 -0.4324 0.0 0
M  V30 3 O 2.4626 0.6006 0.0 0
M  V30 4 N 1.6698 -1.862 0.0 0
M  V30 5 C 2.1143 2.1023 0.0 0
M  V30 6 C 0.6366 -2.9312 0.0 0
M  V30 7 C 3.0032 -2.4506 0.0 0
M  V30 8 C 1.7659 3.6039 0.0 0
M  V30 9 C 0.6487 2.6068 0.0 0
M  V30 10 C 3.1834 3.1354 0.0 0
M  V30 11 N 1.3574 -4.1925 0.0 0
M  V30 12 N -0.8889 -2.739 0.0 0
M  V30 13 C 4.2646 -1.6698 0.0 0
M  V30 14 C 2.811 -3.9042 0.0 0
M  V30 15 C -1.8019 -3.9162 0.0 0
M  V30 16 C -1.5496 -1.3334 0.0 0
M  V30 17 C 5.526 -2.3906 0.0 0
M  V30 18 C 4.2286 -0.1321 0.0 0
M  V30 19 O -1.2133 -5.2497 0.0 0
M  V30 20 O -3.3276 -3.724 0.0 0
M  V30 21 O -3.0753 -1.1412 0.0 0
M  V30 22 O -0.7087 -0.084 0.0 0
M  V30 23 C 6.7874 -1.6097 0.0 0
M  V30 24 C 5.49 0.6366 0.0 0
M  V30 25 C -4.2406 -4.9013 0.0 0
M  V30 26 C -1.3695 1.3214 0.0 0
M  V30 27 N 8.0488 -2.3305 0.0 0
M  V30 28 C 6.7513 -0.072 0.0 0
M  V30 29 C -5.1536 -6.0786 0.0 0
M  V30 30 C -3.652 -6.2348 0.0 0
M  V30 31 C -5.7663 -4.7091 0.0 0
M  V30 32 C -2.0302 2.7269 0.0 0
M  V30 33 C -2.8951 1.5136 0.0 0
M  V30 34 C -0.5285 2.5708 0.0 0
M  V30 35 O 8.0127 0.6967 0.0 0
M  V30 36 C 7.9767 2.2344 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 2 16 21
M  V30 21 1 16 22
M  V30 22 1 17 23
M  V30 23 2 18 24
M  V30 24 1 20 25
M  V30 25 1 22 26
M  V30 26 1 23 27
M  V30 27 2 23 28
M  V30 28 1 25 29
M  V30 29 1 25 30
M  V30 30 1 25 31
M  V30 31 1 26 32
M  V30 32 1 26 33
M  V30 33 1 26 34
M  V30 34 1 28 35
M  V30 35 1 35 36
M  V30 36 1 11 14
M  V30 37 1 24 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00068001.cdx

>  <name>
US20220000118A1-20220106-C00047

>  <Row No>
192

$$$$
US20220000118A1-20220106-C00048
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 15 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.0364 -1.4839 0.0 0
M  V30 3 C 1.2406 -2.2137 0.0 0
M  V30 4 O 1.2041 -3.6976 0.0 0
M  V30 5 C 2.5177 -1.4352 0.0 0
M  V30 6 C 3.7949 -2.165 0.0 0
M  V30 7 C 2.4813 0.1216 0.0 0
M  V30 8 C 5.072 -1.3744 0.0 0
M  V30 9 C 3.7584 0.9122 0.0 0
M  V30 10 N 6.3492 -2.1042 0.0 0 CHG=1
M  V30 11 C 5.0355 0.1824 0.0 0
M  V30 12 O 6.3127 -3.5881 0.0 0
M  V30 13 O 7.6263 -1.3257 0.0 0 CHG=-1
M  V30 14 O 6.3127 0.9608 0.0 0
M  V30 15 C 6.2762 2.5177 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 2 3 4
M  V30 4 1 3 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 8 10
M  V30 10 2 8 11
M  V30 11 2 10 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 14 15
M  V30 15 1 9 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00069001.cdx

>  <name>
US20220000118A1-20220106-C00048

>  <Row No>
193

$$$$
US20220000118A1-20220106-C00049
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 O 10.555 -0.7607 0.0 0
M  V30 3 N 9.2237 -1.4501 0.0 0 CHG=1
M  V30 4 O 9.1524 -2.9002 0.0 0 CHG=-1
M  V30 5 C 7.9162 -0.6537 0.0 0
M  V30 6 C 7.8806 0.8677 0.0 0
M  V30 7 C 6.5969 -1.3669 0.0 0
M  V30 8 O 9.1286 1.6284 0.0 0
M  V30 9 C 6.5612 1.6284 0.0 0
M  V30 10 C 5.2775 -0.6062 0.0 0
M  V30 11 C 9.093 3.1498 0.0 0
M  V30 12 C 5.2418 0.9152 0.0 0
M  V30 13 C 3.97 -1.3312 0.0 0
M  V30 14 N 2.5793 -0.6775 0.0 0
M  V30 15 C 3.7798 -2.7695 0.0 0
M  V30 16 C 1.5571 -1.7354 0.0 0
M  V30 17 N 2.294 -3.0428 0.0 0
M  V30 18 N 0.0356 -1.6997 0.0 0
M  V30 19 C 1.5333 -4.2909 0.0 0
M  V30 20 C -0.7369 -2.9478 0.0 0
M  V30 21 C 0.0118 -4.2553 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 2 3
M  V30 2 1 3 4
M  V30 3 1 3 5
M  V30 4 2 5 6
M  V30 5 1 5 7
M  V30 6 1 6 8
M  V30 7 1 6 9
M  V30 8 2 7 10
M  V30 9 1 8 11
M  V30 10 2 9 12
M  V30 11 1 10 13
M  V30 12 1 13 14
M  V30 13 2 13 15
M  V30 14 2 14 16
M  V30 15 1 15 17
M  V30 16 1 16 18
M  V30 17 1 17 19
M  V30 18 2 18 20
M  V30 19 2 19 21
M  V30 20 1 10 12
M  V30 21 1 16 17
M  V30 22 1 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00070001.cdx

>  <name>
US20220000118A1-20220106-C00049

>  <Row No>
194

$$$$
US20220000118A1-20220106-C00050
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 38 39 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 N -0.0355 1.5179 0.0 0 CHG=1
M  V30 3 O 1.2096 2.2769 0.0 0 CHG=-1
M  V30 4 C -1.3519 2.2769 0.0 0
M  V30 5 C -1.3875 3.7949 0.0 0
M  V30 6 C -2.6683 1.5654 0.0 0
M  V30 7 O -0.1423 4.5539 0.0 0
M  V30 8 C -2.7039 4.5539 0.0 0
M  V30 9 C -3.9847 2.3362 0.0 0
M  V30 10 C -0.1778 6.0719 0.0 0
M  V30 11 C -4.0203 3.8424 0.0 0
M  V30 12 C -5.3011 1.6247 0.0 0
M  V30 13 N -6.6886 2.2769 0.0 0
M  V30 14 C -5.4908 0.1897 0.0 0
M  V30 15 C -7.7085 1.2215 0.0 0
M  V30 16 C -7.0325 3.7594 0.0 0
M  V30 17 N -6.9733 -0.083 0.0 0
M  V30 18 N -9.2147 1.4112 0.0 0
M  V30 19 O -8.4794 4.2575 0.0 0
M  V30 20 O -5.9771 4.7793 0.0 0
M  V30 21 C -9.8669 2.7988 0.0 0
M  V30 22 C -10.116 0.249 0.0 0
M  V30 23 C -6.321 6.2617 0.0 0
M  V30 24 O -11.3731 2.9885 0.0 0
M  V30 25 O -9.0368 4.0321 0.0 0
M  V30 26 O -9.5349 -1.0673 0.0 0
M  V30 27 O -11.6221 0.4387 0.0 0
M  V30 28 C -6.6649 7.7441 0.0 0
M  V30 29 C -7.7678 6.7598 0.0 0
M  V30 30 C -5.2655 7.2816 0.0 0
M  V30 31 C -9.689 5.4197 0.0 0
M  V30 32 C -12.5234 -0.7234 0.0 0
M  V30 33 C -10.3413 6.8072 0.0 0
M  V30 34 C -11.1952 5.6094 0.0 0
M  V30 35 C -8.8589 6.653 0.0 0
M  V30 36 C -13.4247 -1.8856 0.0 0
M  V30 37 C -11.9423 -2.0398 0.0 0
M  V30 38 C -14.0296 -0.5336 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 9 12
M  V30 12 1 12 13
M  V30 13 2 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 1 16 20
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 1 20 23
M  V30 23 2 21 24
M  V30 24 1 21 25
M  V30 25 2 22 26
M  V30 26 1 22 27
M  V30 27 1 23 28
M  V30 28 1 23 29
M  V30 29 1 23 30
M  V30 30 1 25 31
M  V30 31 1 27 32
M  V30 32 1 31 33
M  V30 33 1 31 34
M  V30 34 1 31 35
M  V30 35 1 32 36
M  V30 36 1 32 37
M  V30 37 1 32 38
M  V30 38 1 9 11
M  V30 39 2 15 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00071001.cdx

>  <name>
US20220000118A1-20220106-C00050

>  <Row No>
195

$$$$
US20220000118A1-20220106-C00051
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 36 37 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.3935 -0.4324 0.0 0
M  V30 3 O 2.4626 0.6006 0.0 0
M  V30 4 N 1.6698 -1.862 0.0 0
M  V30 5 C 2.1143 2.1023 0.0 0
M  V30 6 C 0.6366 -2.9312 0.0 0
M  V30 7 C 3.0032 -2.4506 0.0 0
M  V30 8 C 1.7659 3.6039 0.0 0
M  V30 9 C 0.6487 2.6068 0.0 0
M  V30 10 C 3.1834 3.1354 0.0 0
M  V30 11 N 1.3574 -4.1925 0.0 0
M  V30 12 N -0.8889 -2.739 0.0 0
M  V30 13 C 4.2646 -1.6698 0.0 0
M  V30 14 C 2.811 -3.9042 0.0 0
M  V30 15 C -1.8019 -3.9162 0.0 0
M  V30 16 C -1.5496 -1.3334 0.0 0
M  V30 17 C 5.526 -2.3906 0.0 0
M  V30 18 C 4.2286 -0.1321 0.0 0
M  V30 19 O -1.2133 -5.2497 0.0 0
M  V30 20 O -3.3276 -3.724 0.0 0
M  V30 21 O -3.0753 -1.1412 0.0 0
M  V30 22 O -0.7087 -0.084 0.0 0
M  V30 23 C 6.7874 -1.6097 0.0 0
M  V30 24 C 5.49 0.6366 0.0 0
M  V30 25 C -4.2406 -4.9013 0.0 0
M  V30 26 C -1.3695 1.3214 0.0 0
M  V30 27 N 8.0488 -2.3305 0.0 0
M  V30 28 C 6.7513 -0.072 0.0 0
M  V30 29 C -5.1536 -6.0786 0.0 0
M  V30 30 C -3.652 -6.2348 0.0 0
M  V30 31 C -5.7663 -4.7091 0.0 0
M  V30 32 C -2.0302 2.7269 0.0 0
M  V30 33 C -2.8951 1.5136 0.0 0
M  V30 34 C -0.5285 2.5708 0.0 0
M  V30 35 O 8.0127 0.6967 0.0 0
M  V30 36 C 7.9767 2.2344 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 2 16 21
M  V30 21 1 16 22
M  V30 22 1 17 23
M  V30 23 2 18 24
M  V30 24 1 20 25
M  V30 25 1 22 26
M  V30 26 1 23 27
M  V30 27 2 23 28
M  V30 28 1 25 29
M  V30 29 1 25 30
M  V30 30 1 25 31
M  V30 31 1 26 32
M  V30 32 1 26 33
M  V30 33 1 26 34
M  V30 34 1 28 35
M  V30 35 1 35 36
M  V30 36 1 11 14
M  V30 37 1 24 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00072001.cdx

>  <name>
US20220000118A1-20220106-C00051

>  <Row No>
196

$$$$
US20220000118A1-20220106-C00052
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 40 42 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.3998 -0.4344 0.0 0
M  V30 3 O 2.4738 0.6033 0.0 0
M  V30 4 N 1.6773 -1.8704 0.0 0
M  V30 5 C 2.1238 2.1117 0.0 0
M  V30 6 C 0.6395 -2.9444 0.0 0
M  V30 7 C 3.0168 -2.4617 0.0 0
M  V30 8 C 1.7739 3.6202 0.0 0
M  V30 9 C 0.6516 2.6186 0.0 0
M  V30 10 C 3.1978 3.1495 0.0 0
M  V30 11 N 1.3756 -4.2115 0.0 0
M  V30 12 N -0.8929 -2.7513 0.0 0
M  V30 13 C 4.2839 -1.6773 0.0 0
M  V30 14 C 2.8237 -3.9219 0.0 0
M  V30 15 C -1.5566 -1.3394 0.0 0
M  V30 16 C -1.8101 -3.9339 0.0 0
M  V30 17 C 5.551 -2.4014 0.0 0
M  V30 18 C 4.2477 -0.1327 0.0 0
M  V30 19 C 3.8977 -4.8872 0.0 0
M  V30 20 O -3.0892 -1.1464 0.0 0
M  V30 21 O -0.7119 -0.0844 0.0 0
M  V30 22 O -1.2188 -5.2734 0.0 0
M  V30 23 O -3.3426 -3.7408 0.0 0
M  V30 24 C 6.818 -1.617 0.0 0
M  V30 25 C 5.5147 0.6516 0.0 0
M  V30 26 C 3.5478 -6.3233 0.0 0
M  V30 27 C 5.2975 -4.3804 0.0 0
M  V30 28 C -1.3756 1.3274 0.0 0
M  V30 29 C -4.2597 -4.9234 0.0 0
M  V30 30 N 8.0851 -2.3531 0.0 0
M  V30 31 C 6.7818 -0.0724 0.0 0
M  V30 32 C 4.6218 -7.2887 0.0 0
M  V30 33 C 6.3715 -5.3458 0.0 0
M  V30 34 C -2.0393 2.7392 0.0 0
M  V30 35 C -2.9082 1.5204 0.0 0
M  V30 36 C -0.5309 2.5824 0.0 0
M  V30 37 C -5.1769 -6.1061 0.0 0
M  V30 38 C -3.6684 -6.2629 0.0 0
M  V30 39 C -5.7923 -4.7304 0.0 0
M  V30 40 C 6.0216 -6.7818 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 1 14 19
M  V30 19 2 15 20
M  V30 20 1 15 21
M  V30 21 2 16 22
M  V30 22 1 16 23
M  V30 23 1 17 24
M  V30 24 2 18 25
M  V30 25 2 19 26
M  V30 26 1 19 27
M  V30 27 1 21 28
M  V30 28 1 23 29
M  V30 29 1 24 30
M  V30 30 2 24 31
M  V30 31 1 26 32
M  V30 32 2 27 33
M  V30 33 1 28 34
M  V30 34 1 28 35
M  V30 35 1 28 36
M  V30 36 1 29 37
M  V30 37 1 29 38
M  V30 38 1 29 39
M  V30 39 2 32 40
M  V30 40 1 11 14
M  V30 41 1 25 31
M  V30 42 1 33 40
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00073001.cdx

>  <name>
US20220000118A1-20220106-C00052

>  <Row No>
197

$$$$
US20220000118A1-20220106-C00053
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 37 38 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.9067 1.2408 0.0 0
M  V30 3 N -2.4339 1.2766 0.0 0
M  V30 4 C -0.4772 2.6964 0.0 0
M  V30 5 C -2.935 2.7322 0.0 0
M  V30 6 N -1.718 3.6031 0.0 0
M  V30 7 C 0.9067 3.1975 0.0 0
M  V30 8 N -4.3906 3.2333 0.0 0
M  V30 9 C -1.7538 5.1303 0.0 0
M  V30 10 C 1.9686 2.243 0.0 0
M  V30 11 C 1.1811 4.6889 0.0 0
M  V30 12 C -4.7366 4.7246 0.0 0
M  V30 13 C -5.524 2.2788 0.0 0
M  V30 14 O -3.0782 5.9058 0.0 0
M  V30 15 O -0.5011 5.9058 0.0 0
M  V30 16 C 3.3526 2.7441 0.0 0
M  V30 17 C 2.5651 5.19 0.0 0
M  V30 18 O -6.1922 5.2258 0.0 0
M  V30 19 O -3.6747 5.7507 0.0 0
M  V30 20 O -5.2496 0.859 0.0 0
M  V30 21 O -6.9796 2.7799 0.0 0
M  V30 22 C -0.5368 7.433 0.0 0
M  V30 23 N 4.4144 1.7896 0.0 0 CHG=1
M  V30 24 C 3.627 4.2355 0.0 0
M  V30 25 C -4.0207 7.2421 0.0 0
M  V30 26 C -8.1131 1.8254 0.0 0
M  V30 27 C -0.5726 8.9602 0.0 0
M  V30 28 C -1.8612 8.2085 0.0 0
M  V30 29 C 0.7158 8.2085 0.0 0
M  V30 30 O 4.0684 0.3698 0.0 0
M  V30 31 O 5.7984 2.2907 0.0 0 CHG=-1
M  V30 32 C -4.3667 8.7335 0.0 0
M  V30 33 C -5.4763 7.7432 0.0 0
M  V30 34 C -2.9589 8.2682 0.0 0
M  V30 35 C -9.2465 0.8709 0.0 0
M  V30 36 C -7.8387 0.4056 0.0 0
M  V30 37 C -9.5687 2.3265 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 2 2 4
M  V30 4 2 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 2 7 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 8 13
M  V30 13 2 9 14
M  V30 14 1 9 15
M  V30 15 1 10 16
M  V30 16 2 11 17
M  V30 17 2 12 18
M  V30 18 1 12 19
M  V30 19 2 13 20
M  V30 20 1 13 21
M  V30 21 1 15 22
M  V30 22 1 16 23
M  V30 23 2 16 24
M  V30 24 1 19 25
M  V30 25 1 21 26
M  V30 26 1 22 27
M  V30 27 1 22 28
M  V30 28 1 22 29
M  V30 29 2 23 30
M  V30 30 1 23 31
M  V30 31 1 25 32
M  V30 32 1 25 33
M  V30 33 1 25 34
M  V30 34 1 26 35
M  V30 35 1 26 36
M  V30 36 1 26 37
M  V30 37 1 5 6
M  V30 38 1 17 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00074001.cdx

>  <name>
US20220000118A1-20220106-C00053

>  <Row No>
198

$$$$
US20220000118A1-20220106-C00054
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 42 44 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 N 0.2742 1.4904 0.0 0 CHG=1
M  V30 3 O 1.6573 1.9912 0.0 0 CHG=-1
M  V30 4 C -0.8584 2.5158 0.0 0
M  V30 5 C -2.3131 2.0865 0.0 0
M  V30 6 C -0.5842 4.0062 0.0 0
M  V30 7 C -3.4458 3.112 0.0 0
M  V30 8 C -1.7169 5.0316 0.0 0
M  V30 9 C -4.9005 2.6827 0.0 0
M  V30 10 C -3.1716 4.6024 0.0 0
M  V30 11 N -6.1405 3.5889 0.0 0
M  V30 12 C -5.4013 1.2996 0.0 0
M  V30 13 C -7.3805 2.7543 0.0 0
M  V30 14 C -6.1763 5.1151 0.0 0
M  V30 15 N -6.9275 1.3354 0.0 0
M  V30 16 C -4.5666 0.1311 0.0 0
M  V30 17 N -8.8352 3.255 0.0 0
M  V30 18 O -7.4998 5.8901 0.0 0
M  V30 19 O -4.9243 5.8901 0.0 0
M  V30 20 C -5.2224 -1.1923 0.0 0
M  V30 21 C -3.1239 0.3219 0.0 0
M  V30 22 C -9.9679 2.3012 0.0 0
M  V30 23 C -9.181 4.7455 0.0 0
M  V30 24 C -4.9601 7.4163 0.0 0
M  V30 25 C -4.3878 -2.3608 0.0 0
M  V30 26 C -2.2892 -0.8465 0.0 0
M  V30 27 O -9.6937 0.8823 0.0 0
M  V30 28 O -11.4226 2.802 0.0 0
M  V30 29 O -10.6356 5.2463 0.0 0
M  V30 30 O -8.1198 5.7709 0.0 0
M  V30 31 C -4.9959 8.9425 0.0 0
M  V30 32 C -6.2836 8.1913 0.0 0
M  V30 33 C -3.7081 8.1913 0.0 0
M  V30 34 C -2.945 -2.17 0.0 0
M  V30 35 C -12.5553 1.8481 0.0 0
M  V30 36 C -8.4656 7.2613 0.0 0
M  V30 37 C -13.688 0.8942 0.0 0
M  V30 38 C -12.2811 0.4292 0.0 0
M  V30 39 C -14.01 2.3489 0.0 0
M  V30 40 C -8.8114 8.7517 0.0 0
M  V30 41 C -9.9202 7.7621 0.0 0
M  V30 42 C -7.4044 8.2867 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 2 7 10
M  V30 10 1 9 11
M  V30 11 2 9 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 2 14 18
M  V30 18 1 14 19
M  V30 19 2 16 20
M  V30 20 1 16 21
M  V30 21 1 17 22
M  V30 22 1 17 23
M  V30 23 1 19 24
M  V30 24 1 20 25
M  V30 25 2 21 26
M  V30 26 2 22 27
M  V30 27 1 22 28
M  V30 28 2 23 29
M  V30 29 1 23 30
M  V30 30 1 24 31
M  V30 31 1 24 32
M  V30 32 1 24 33
M  V30 33 2 25 34
M  V30 34 1 28 35
M  V30 35 1 30 36
M  V30 36 1 35 37
M  V30 37 1 35 38
M  V30 38 1 35 39
M  V30 39 1 36 40
M  V30 40 1 36 41
M  V30 41 1 36 42
M  V30 42 1 8 10
M  V30 43 2 13 15
M  V30 44 1 26 34
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00075001.cdx

>  <name>
US20220000118A1-20220106-C00054

>  <Row No>
199

$$$$
US20220000118A1-20220106-C00055
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 40 42 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.436 -0.2896 0.0 0
M  V30 3 O 2.4136 0.8568 0.0 0
M  V30 4 N 1.8584 -1.6895 0.0 0
M  V30 5 C 1.9188 2.3291 0.0 0
M  V30 6 C 0.9413 -2.8601 0.0 0
M  V30 7 C 3.2583 -2.136 0.0 0
M  V30 8 C 1.424 3.8014 0.0 0
M  V30 9 C 0.4103 2.6911 0.0 0
M  V30 10 C 2.8963 3.4755 0.0 0
M  V30 11 N 1.774 -4.0427 0.0 0
M  V30 12 N -0.6034 -2.8118 0.0 0
M  V30 13 C 4.441 -1.2309 0.0 0
M  V30 14 C 3.2101 -3.6083 0.0 0
M  V30 15 C -1.3757 -1.4723 0.0 0
M  V30 16 C -1.3878 -4.079 0.0 0
M  V30 17 C 5.7805 -1.8222 0.0 0
M  V30 18 C 4.26 0.3017 0.0 0
M  V30 19 C 4.3807 -4.4531 0.0 0
M  V30 20 O -2.9204 -1.424 0.0 0
M  V30 21 O -0.6396 -0.1327 0.0 0
M  V30 22 O -0.6637 -5.3461 0.0 0
M  V30 23 O -2.9325 -4.0307 0.0 0
M  V30 24 C 6.9632 -0.9171 0.0 0
M  V30 25 C 5.4426 1.2068 0.0 0
M  V30 26 C 4.1755 -5.9133 0.0 0
M  V30 27 C 5.7202 -3.8014 0.0 0
M  V30 28 C -1.4119 1.2068 0.0 0
M  V30 29 C -3.7169 -5.2978 0.0 0
M  V30 30 N 8.3028 -1.5085 0.0 0
M  V30 31 C 6.7822 0.6154 0.0 0
M  V30 32 C 5.3461 -6.7581 0.0 0
M  V30 33 C 6.8908 -4.6461 0.0 0
M  V30 34 C -2.1963 2.5463 0.0 0
M  V30 35 C -2.9566 1.255 0.0 0
M  V30 36 C -0.6758 2.5463 0.0 0
M  V30 37 C -4.5013 -6.565 0.0 0
M  V30 38 C -2.9928 -6.565 0.0 0
M  V30 39 C -5.2616 -5.2496 0.0 0
M  V30 40 C 6.6857 -6.1064 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 1 14 19
M  V30 19 2 15 20
M  V30 20 1 15 21
M  V30 21 2 16 22
M  V30 22 1 16 23
M  V30 23 1 17 24
M  V30 24 2 18 25
M  V30 25 2 19 26
M  V30 26 1 19 27
M  V30 27 1 21 28
M  V30 28 1 23 29
M  V30 29 1 24 30
M  V30 30 2 24 31
M  V30 31 1 26 32
M  V30 32 2 27 33
M  V30 33 1 28 34
M  V30 34 1 28 35
M  V30 35 1 28 36
M  V30 36 1 29 37
M  V30 37 1 29 38
M  V30 38 1 29 39
M  V30 39 2 32 40
M  V30 40 1 11 14
M  V30 41 1 25 31
M  V30 42 1 33 40
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00076001.cdx

>  <name>
US20220000118A1-20220106-C00055

>  <Row No>
200

$$$$
US20220000118A1-20220106-C00056
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 34 35 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.393 -0.4443 0.0 0
M  V30 3 O 2.4738 0.5884 0.0 0
M  V30 4 N 1.6692 -1.8733 0.0 0
M  V30 5 C 2.1255 2.0895 0.0 0
M  V30 6 C 0.6364 -2.9421 0.0 0
M  V30 7 C 3.0022 -2.4618 0.0 0
M  V30 8 C 1.7773 3.5906 0.0 0
M  V30 9 C 0.6604 2.6059 0.0 0
M  V30 10 C 3.2063 3.1223 0.0 0
M  V30 11 N 1.357 -4.2031 0.0 0
M  V30 12 N -0.8886 -2.738 0.0 0
M  V30 13 C 4.2631 -1.6812 0.0 0
M  V30 14 C 2.798 -3.9149 0.0 0
M  V30 15 C -1.8013 -3.9149 0.0 0
M  V30 16 C -1.5371 -1.3329 0.0 0
M  V30 17 C 5.524 -2.4137 0.0 0
M  V30 18 C 4.2271 -0.1441 0.0 0
M  V30 19 O -1.2249 -5.2478 0.0 0
M  V30 20 O -3.3264 -3.7107 0.0 0
M  V30 21 O -3.0622 -1.1288 0.0 0
M  V30 22 O -0.6965 -0.084 0.0 0
M  V30 23 C 6.785 -1.6332 0.0 0
M  V30 24 C 5.488 0.6244 0.0 0
M  V30 25 C -4.2391 -4.8876 0.0 0
M  V30 26 C -1.3449 1.3209 0.0 0
M  V30 27 C 6.7489 -0.096 0.0 0
M  V30 28 C -5.1518 -6.0644 0.0 0
M  V30 29 C -3.6627 -6.2206 0.0 0
M  V30 30 C -5.7642 -4.6834 0.0 0
M  V30 31 C -1.9934 2.726 0.0 0
M  V30 32 C -2.8701 1.5251 0.0 0
M  V30 33 C -0.5043 2.5699 0.0 0
M  V30 34 N 8.0099 0.6724 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 2 16 21
M  V30 21 1 16 22
M  V30 22 1 17 23
M  V30 23 2 18 24
M  V30 24 1 20 25
M  V30 25 1 22 26
M  V30 26 2 23 27
M  V30 27 1 25 28
M  V30 28 1 25 29
M  V30 29 1 25 30
M  V30 30 1 26 31
M  V30 31 1 26 32
M  V30 32 1 26 33
M  V30 33 1 27 34
M  V30 34 1 11 14
M  V30 35 1 24 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00077001.cdx

>  <name>
US20220000118A1-20220106-C00056

>  <Row No>
201

$$$$
US20220000118A1-20220106-C00057
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -1.5228 0.0356 0.0 0
M  V30 3 O 9.7081 1.0469 0.0 0
M  V30 4 N 8.3875 1.8202 0.0 0 CHG=1
M  V30 5 O 8.3518 3.3431 0.0 0 CHG=-1
M  V30 6 C 7.0669 1.1064 0.0 0
M  V30 7 C 7.0312 -0.345 0.0 0
M  V30 8 C 5.7463 1.8797 0.0 0
M  V30 9 C 5.7106 -1.0588 0.0 0
M  V30 10 C 4.4257 1.1659 0.0 0
M  V30 11 C 4.39 -0.2855 0.0 0
M  V30 12 C 3.0694 -0.9993 0.0 0
M  V30 13 N 1.6775 -0.345 0.0 0
M  V30 14 C 2.8672 -2.4389 0.0 0
M  V30 15 C 0.6543 -1.4038 0.0 0
M  V30 16 N 1.38 -2.7125 0.0 0
M  V30 17 N -0.8685 -1.3681 0.0 0
M  V30 18 C 0.6186 -3.9617 0.0 0
M  V30 19 C -1.6418 -2.6174 0.0 0
M  V30 20 C -0.9041 -3.9261 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 3 4
M  V30 3 1 4 5
M  V30 4 1 4 6
M  V30 5 2 6 7
M  V30 6 1 6 8
M  V30 7 1 7 9
M  V30 8 2 8 10
M  V30 9 2 9 11
M  V30 10 1 11 12
M  V30 11 1 12 13
M  V30 12 2 12 14
M  V30 13 2 13 15
M  V30 14 1 14 16
M  V30 15 1 15 17
M  V30 16 1 16 18
M  V30 17 2 17 19
M  V30 18 2 18 20
M  V30 19 1 10 11
M  V30 20 1 15 16
M  V30 21 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00078001.cdx

>  <name>
US20220000118A1-20220106-C00057

>  <Row No>
202

$$$$
US20220000118A1-20220106-C00058
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 16 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 N -1.3194 0.7726 0.0 0 CHG=1
M  V30 3 O -1.3551 2.2942 0.0 0 CHG=-1
M  V30 4 C -2.6389 0.0594 0.0 0
M  V30 5 C -2.6746 -1.3908 0.0 0
M  V30 6 C -3.9584 0.8321 0.0 0
M  V30 7 C -3.9941 -2.104 0.0 0
M  V30 8 C -5.2779 0.1188 0.0 0
M  V30 9 C -5.3136 -1.3313 0.0 0
M  V30 10 C -6.6331 -2.0446 0.0 0
M  V30 11 C -6.8351 -3.4829 0.0 0
M  V30 12 C -8.0239 -1.3908 0.0 0
M  V30 13 N -8.3211 -3.7563 0.0 0
M  V30 14 C -9.0462 -2.4487 0.0 0
M  V30 15 N -10.5559 -2.2466 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 2 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 1 8 9
M  V30 16 2 13 14
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00079001.cdx

>  <name>
US20220000118A1-20220106-C00058

>  <Row No>
203

$$$$
US20220000118A1-20220106-C00059
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 36 37 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 N -1.3176 0.7715 0.0 0 CHG=1
M  V30 3 O -1.3532 2.291 0.0 0 CHG=-1
M  V30 4 C -2.6353 0.0593 0.0 0
M  V30 5 C -2.6709 -1.3888 0.0 0
M  V30 6 C -3.9529 0.8309 0.0 0
M  V30 7 C -3.9885 -2.1011 0.0 0
M  V30 8 C -5.2706 0.1187 0.0 0
M  V30 9 C -5.3062 -1.3295 0.0 0
M  V30 10 C -6.6238 -2.0417 0.0 0
M  V30 11 N -8.0127 -1.3888 0.0 0
M  V30 12 C -6.8256 -3.4781 0.0 0
M  V30 13 C -9.0336 -2.4453 0.0 0
M  V30 14 C -8.357 0.0949 0.0 0
M  V30 15 N -8.3095 -3.7511 0.0 0
M  V30 16 N -10.5412 -2.2435 0.0 0
M  V30 17 O -9.8052 0.6054 0.0 0
M  V30 18 O -7.2886 1.1158 0.0 0
M  V30 19 C -11.4434 -3.4069 0.0 0
M  V30 20 C -11.1822 -0.8546 0.0 0
M  V30 21 C -7.6328 2.5996 0.0 0
M  V30 22 O -10.8736 -4.7245 0.0 0
M  V30 23 O -12.9509 -3.2051 0.0 0
M  V30 24 O -12.6898 -0.6528 0.0 0
M  V30 25 O -10.3512 0.3798 0.0 0
M  V30 26 C -7.9771 4.0835 0.0 0
M  V30 27 C -9.0811 3.1101 0.0 0
M  V30 28 C -6.5645 3.6205 0.0 0
M  V30 29 C -13.8531 -4.3684 0.0 0
M  V30 30 C -10.9923 1.7687 0.0 0
M  V30 31 C -14.7553 -5.5317 0.0 0
M  V30 32 C -13.2833 -5.686 0.0 0
M  V30 33 C -15.3607 -4.1666 0.0 0
M  V30 34 C -11.6333 3.1576 0.0 0
M  V30 35 C -12.4999 1.9705 0.0 0
M  V30 36 C -10.1613 3.0033 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 2 7 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 2 10 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 1 14 18
M  V30 18 1 16 19
M  V30 19 1 16 20
M  V30 20 1 18 21
M  V30 21 2 19 22
M  V30 22 1 19 23
M  V30 23 2 20 24
M  V30 24 1 20 25
M  V30 25 1 21 26
M  V30 26 1 21 27
M  V30 27 1 21 28
M  V30 28 1 23 29
M  V30 29 1 25 30
M  V30 30 1 29 31
M  V30 31 1 29 32
M  V30 32 1 29 33
M  V30 33 1 30 34
M  V30 34 1 30 35
M  V30 35 1 30 36
M  V30 36 1 8 9
M  V30 37 2 13 15
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00080001.cdx

>  <name>
US20220000118A1-20220106-C00059

>  <Row No>
204

$$$$
US20220000118A1-20220106-C00060
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 34 35 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.393 -0.4443 0.0 0
M  V30 3 O 2.4738 0.5884 0.0 0
M  V30 4 N 1.6692 -1.8733 0.0 0
M  V30 5 C 2.1255 2.0895 0.0 0
M  V30 6 C 0.6364 -2.9421 0.0 0
M  V30 7 C 3.0022 -2.4618 0.0 0
M  V30 8 C 1.7773 3.5906 0.0 0
M  V30 9 C 0.6604 2.6059 0.0 0
M  V30 10 C 3.2063 3.1223 0.0 0
M  V30 11 N 1.357 -4.2031 0.0 0
M  V30 12 N -0.8886 -2.738 0.0 0
M  V30 13 C 4.2631 -1.6812 0.0 0
M  V30 14 C 2.798 -3.9149 0.0 0
M  V30 15 C -1.5371 -1.3329 0.0 0
M  V30 16 C -1.8013 -3.9149 0.0 0
M  V30 17 C 5.524 -2.4137 0.0 0
M  V30 18 C 4.2271 -0.1441 0.0 0
M  V30 19 O -3.0622 -1.1288 0.0 0
M  V30 20 O -0.6965 -0.084 0.0 0
M  V30 21 O -1.2249 -5.2478 0.0 0
M  V30 22 O -3.3264 -3.7107 0.0 0
M  V30 23 C 6.785 -1.6332 0.0 0
M  V30 24 C 5.488 0.6244 0.0 0
M  V30 25 C -1.3449 1.3209 0.0 0
M  V30 26 C -4.2391 -4.8876 0.0 0
M  V30 27 C 6.7489 -0.096 0.0 0
M  V30 28 C -1.9934 2.726 0.0 0
M  V30 29 C -2.8701 1.5251 0.0 0
M  V30 30 C -0.5043 2.5699 0.0 0
M  V30 31 C -5.1518 -6.0644 0.0 0
M  V30 32 C -3.6627 -6.2206 0.0 0
M  V30 33 C -5.7642 -4.6834 0.0 0
M  V30 34 N 8.0099 0.6724 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 2 16 21
M  V30 21 1 16 22
M  V30 22 1 17 23
M  V30 23 2 18 24
M  V30 24 1 20 25
M  V30 25 1 22 26
M  V30 26 2 23 27
M  V30 27 1 25 28
M  V30 28 1 25 29
M  V30 29 1 25 30
M  V30 30 1 26 31
M  V30 31 1 26 32
M  V30 32 1 26 33
M  V30 33 1 27 34
M  V30 34 1 11 14
M  V30 35 1 24 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00081001.cdx

>  <name>
US20220000118A1-20220106-C00060

>  <Row No>
205

$$$$
US20220000118A1-20220106-C00061
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 36 38 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.3862 -0.4421 0.0 0
M  V30 3 O 2.4617 0.5855 0.0 0
M  V30 4 N 1.661 -1.8761 0.0 0
M  V30 5 C 2.1151 2.0912 0.0 0
M  V30 6 C 0.6214 -2.9517 0.0 0
M  V30 7 C 2.9995 -2.4617 0.0 0
M  V30 8 C 1.7686 3.597 0.0 0
M  V30 9 C 0.6572 2.6051 0.0 0
M  V30 10 C 3.1907 3.119 0.0 0
M  V30 11 N 1.3503 -4.2184 0.0 0
M  V30 12 N -0.9082 -2.7485 0.0 0
M  V30 13 C 4.3379 -1.8044 0.0 0
M  V30 14 C 2.7963 -3.9196 0.0 0
M  V30 15 C -1.8164 -3.9196 0.0 0
M  V30 16 C -1.5654 -1.3384 0.0 0
M  V30 17 C 5.509 -2.641 0.0 0
M  V30 18 C 4.4694 -0.2748 0.0 0
M  V30 19 C 3.9674 -4.7562 0.0 0
M  V30 20 O -1.2308 -5.2581 0.0 0
M  V30 21 O -3.346 -3.7165 0.0 0
M  V30 22 O -3.0951 -1.1352 0.0 0
M  V30 23 O -0.7289 -0.0956 0.0 0
M  V30 24 C 6.8475 -1.9837 0.0 0
M  V30 25 C 5.3059 -4.0989 0.0 0
M  V30 26 C 5.8078 0.3824 0.0 0
M  V30 27 C -4.2542 -4.8876 0.0 0
M  V30 28 C -1.3862 1.3145 0.0 0
M  V30 29 C 6.9789 -0.4541 0.0 0
M  V30 30 N 5.9392 1.912 0.0 0
M  V30 31 C -5.1625 -6.0587 0.0 0
M  V30 32 C -3.6687 -6.226 0.0 0
M  V30 33 C -5.7839 -4.6845 0.0 0
M  V30 34 C -2.0434 2.7246 0.0 0
M  V30 35 C -2.9158 1.5176 0.0 0
M  V30 36 C -0.5497 2.5573 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 1 14 19
M  V30 19 2 15 20
M  V30 20 1 15 21
M  V30 21 2 16 22
M  V30 22 1 16 23
M  V30 23 1 17 24
M  V30 24 1 17 25
M  V30 25 2 18 26
M  V30 26 1 21 27
M  V30 27 1 23 28
M  V30 28 2 24 29
M  V30 29 1 26 30
M  V30 30 1 27 31
M  V30 31 1 27 32
M  V30 32 1 27 33
M  V30 33 1 28 34
M  V30 34 1 28 35
M  V30 35 1 28 36
M  V30 36 1 11 14
M  V30 37 1 19 25
M  V30 38 1 26 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00082001.cdx

>  <name>
US20220000118A1-20220106-C00061

>  <Row No>
206

$$$$
US20220000118A1-20220106-C00062
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 36 38 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.3862 -0.4421 0.0 0
M  V30 3 O 2.4617 0.5855 0.0 0
M  V30 4 N 1.661 -1.8761 0.0 0
M  V30 5 C 2.1151 2.0912 0.0 0
M  V30 6 C 0.6214 -2.9517 0.0 0
M  V30 7 C 2.9995 -2.4617 0.0 0
M  V30 8 C 1.7686 3.597 0.0 0
M  V30 9 C 0.6572 2.6051 0.0 0
M  V30 10 C 3.1907 3.119 0.0 0
M  V30 11 N 1.3503 -4.2184 0.0 0
M  V30 12 N -0.9082 -2.7485 0.0 0
M  V30 13 C 4.3379 -1.8044 0.0 0
M  V30 14 C 2.7963 -3.9196 0.0 0
M  V30 15 C -1.8164 -3.9196 0.0 0
M  V30 16 C -1.5654 -1.3384 0.0 0
M  V30 17 C 5.509 -2.641 0.0 0
M  V30 18 C 4.4694 -0.2748 0.0 0
M  V30 19 C 3.9674 -4.7562 0.0 0
M  V30 20 O -1.2308 -5.2581 0.0 0
M  V30 21 O -3.346 -3.7165 0.0 0
M  V30 22 O -3.0951 -1.1352 0.0 0
M  V30 23 O -0.7289 -0.0956 0.0 0
M  V30 24 C 6.8475 -1.9837 0.0 0
M  V30 25 C 5.3059 -4.0989 0.0 0
M  V30 26 C 5.8078 0.3824 0.0 0
M  V30 27 C -4.2542 -4.8876 0.0 0
M  V30 28 C -1.3862 1.3145 0.0 0
M  V30 29 C 6.9789 -0.4541 0.0 0
M  V30 30 N 5.9392 1.912 0.0 0
M  V30 31 C -5.1625 -6.0587 0.0 0
M  V30 32 C -3.6687 -6.226 0.0 0
M  V30 33 C -5.7839 -4.6845 0.0 0
M  V30 34 C -2.0434 2.7246 0.0 0
M  V30 35 C -2.9158 1.5176 0.0 0
M  V30 36 C -0.5497 2.5573 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 1 14 19
M  V30 19 2 15 20
M  V30 20 1 15 21
M  V30 21 2 16 22
M  V30 22 1 16 23
M  V30 23 2 17 24
M  V30 24 1 17 25
M  V30 25 1 18 26
M  V30 26 1 21 27
M  V30 27 1 23 28
M  V30 28 1 24 29
M  V30 29 1 26 30
M  V30 30 1 27 31
M  V30 31 1 27 32
M  V30 32 1 27 33
M  V30 33 1 28 34
M  V30 34 1 28 35
M  V30 35 1 28 36
M  V30 36 1 11 14
M  V30 37 2 19 25
M  V30 38 2 26 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00083001.cdx

>  <name>
US20220000118A1-20220106-C00062

>  <Row No>
207

$$$$
US20220000118A1-20220106-C00063
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 16 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C 1.2774 0.7786 0.0 0 CFG=2
M  V30 3 C 2.5548 0.0486 0.0 0
M  V30 4 C 1.2409 2.3358 0.0 0
M  V30 5 O 2.5183 -1.4355 0.0 0
M  V30 6 C 3.8322 0.8394 0.0 0
M  V30 7 C 2.5183 3.1266 0.0 0
M  V30 8 C 3.7957 2.3966 0.0 0
M  V30 9 C 5.1096 0.1094 0.0 0
M  V30 10 C 5.0731 3.1874 0.0 0
M  V30 11 C 6.387 0.9002 0.0 0
M  V30 12 C 6.3505 2.4574 0.0 0
M  V30 13 N 7.6644 0.1703 0.0 0 CHG=1
M  V30 14 O 7.6279 -1.3139 0.0 0
M  V30 15 O 8.9418 0.9489 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=1
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 6 8
M  V30 8 1 6 9
M  V30 9 1 8 10
M  V30 10 2 9 11
M  V30 11 2 10 12
M  V30 12 1 11 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 7 8
M  V30 16 1 11 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00084001.cdx

>  <name>
US20220000118A1-20220106-C00063

>  <Row No>
208

$$$$
US20220000118A1-20220106-C00064
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -1.5172 0.0355 0.0 0
M  V30 3 O 9.2931 -2.8448 0.0 0
M  V30 4 N 9.2575 -1.3275 0.0 0 CHG=1
M  V30 5 O 10.5021 -0.5571 0.0 0 CHG=-1
M  V30 6 C 7.9418 -0.5571 0.0 0
M  V30 7 C 6.626 -1.2683 0.0 0
M  V30 8 C 7.9062 0.9601 0.0 0
M  V30 9 C 5.3103 -0.5096 0.0 0
M  V30 10 C 6.5905 1.7306 0.0 0
M  V30 11 C 5.2747 1.0075 0.0 0
M  V30 12 C 3.9946 -1.2209 0.0 0
M  V30 13 C 3.959 1.7661 0.0 0
M  V30 14 N 3.6508 -2.6314 0.0 0
M  V30 15 C 2.6788 -0.4504 0.0 0
M  V30 16 C 2.6433 1.0549 0.0 0
M  V30 17 C 2.1454 -2.75 0.0 0
M  V30 18 N 1.5528 -1.3987 0.0 0
M  V30 19 N 1.2446 -3.9116 0.0 0
M  V30 20 C 0.0474 -1.209 0.0 0
M  V30 21 C -0.2607 -3.7219 0.0 0
M  V30 22 C -0.8534 -2.3706 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 3 4
M  V30 3 1 4 5
M  V30 4 1 4 6
M  V30 5 2 6 7
M  V30 6 1 6 8
M  V30 7 1 7 9
M  V30 8 2 8 10
M  V30 9 2 9 11
M  V30 10 1 9 12
M  V30 11 1 11 13
M  V30 12 1 12 14
M  V30 13 2 12 15
M  V30 14 1 13 16
M  V30 15 2 14 17
M  V30 16 1 15 18
M  V30 17 1 17 19
M  V30 18 1 18 20
M  V30 19 2 19 21
M  V30 20 2 20 22
M  V30 21 1 10 11
M  V30 22 1 15 16
M  V30 23 1 17 18
M  V30 24 1 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00085001.cdx

>  <name>
US20220000118A1-20220106-C00064

>  <Row No>
209

$$$$
US20220000118A1-20220106-C00065
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 38 40 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 N -1.4009 -0.5817 0.0 0 CHG=1
M  V30 3 O -2.6357 0.3205 0.0 0 CHG=-1
M  V30 4 C -1.6028 -2.0302 0.0 0
M  V30 5 C -3.0038 -2.612 0.0 0
M  V30 6 C -0.4392 -2.8613 0.0 0
M  V30 7 C -3.2056 -4.0604 0.0 0
M  V30 8 C -0.6411 -4.3098 0.0 0
M  V30 9 C -2.0421 -4.8915 0.0 0
M  V30 10 C -4.6066 -4.6422 0.0 0
M  V30 11 C -2.2439 -6.34 0.0 0
M  V30 12 N -6.0076 -3.9892 0.0 0
M  V30 13 C -4.8084 -6.0907 0.0 0
M  V30 14 C -3.6449 -6.9218 0.0 0
M  V30 15 C -7.0405 -5.0577 0.0 0
M  V30 16 C -6.3519 -2.4932 0.0 0
M  V30 17 N -6.3044 -6.3638 0.0 0
M  V30 18 N -8.5602 -4.8559 0.0 0
M  V30 19 O -7.8004 -1.9827 0.0 0
M  V30 20 O -5.2833 -1.4722 0.0 0
M  V30 21 C -9.2132 -3.4549 0.0 0
M  V30 22 C -9.4625 -6.0194 0.0 0
M  V30 23 C -5.6276 0.0237 0.0 0
M  V30 24 O -10.7329 -3.2531 0.0 0
M  V30 25 O -8.3821 -2.2202 0.0 0
M  V30 26 O -8.8808 -7.3492 0.0 0
M  V30 27 O -10.9823 -5.8176 0.0 0
M  V30 28 C -5.9719 1.5197 0.0 0
M  V30 29 C -7.0761 0.5342 0.0 0
M  V30 30 C -4.5591 1.0448 0.0 0
M  V30 31 C -9.0351 -0.8192 0.0 0
M  V30 32 C -11.8846 -6.9811 0.0 0
M  V30 33 C -9.6881 0.5817 0.0 0
M  V30 34 C -10.5548 -0.6173 0.0 0
M  V30 35 C -8.204 0.4155 0.0 0
M  V30 36 C -12.7869 -8.1447 0.0 0
M  V30 37 C -11.3028 -8.3109 0.0 0
M  V30 38 C -13.4043 -6.7793 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 2 7 9
M  V30 9 1 7 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 2 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 1 16 20
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 1 20 23
M  V30 23 2 21 24
M  V30 24 1 21 25
M  V30 25 2 22 26
M  V30 26 1 22 27
M  V30 27 1 23 28
M  V30 28 1 23 29
M  V30 29 1 23 30
M  V30 30 1 25 31
M  V30 31 1 27 32
M  V30 32 1 31 33
M  V30 33 1 31 34
M  V30 34 1 31 35
M  V30 35 1 32 36
M  V30 36 1 32 37
M  V30 37 1 32 38
M  V30 38 1 8 9
M  V30 39 1 13 14
M  V30 40 2 15 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00086001.cdx

>  <name>
US20220000118A1-20220106-C00065

>  <Row No>
210

$$$$
US20220000118A1-20220106-C00066
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 72 76 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.3861 -0.4421 0.0 0
M  V30 3 O 2.4616 0.5855 0.0 0
M  V30 4 N 1.661 -1.876 0.0 0
M  V30 5 C 2.115 2.0911 0.0 0
M  V30 6 C 0.6213 -2.9515 0.0 0
M  V30 7 C 2.9993 -2.4616 0.0 0
M  V30 8 C 1.7685 3.5968 0.0 0
M  V30 9 C 0.6572 2.605 0.0 0
M  V30 10 C 3.1905 3.1188 0.0 0
M  V30 11 N 1.3503 -4.2182 0.0 0
M  V30 12 N -0.9081 -2.7484 0.0 0
M  V30 13 C 4.3377 -1.8043 0.0 0
M  V30 14 C 2.7962 -3.9194 0.0 0
M  V30 15 C -1.5654 -1.3383 0.0 0
M  V30 16 C -1.8163 -3.9194 0.0 0
M  V30 17 C 5.5087 -2.6408 0.0 0
M  V30 18 C 4.4691 -0.2748 0.0 0
M  V30 19 C 3.9672 -4.7559 0.0 0
M  V30 20 O -3.0949 -1.1352 0.0 0
M  V30 21 O -0.7289 -0.0955 0.0 0
M  V30 22 O -1.2308 -5.2578 0.0 0
M  V30 23 O -3.3459 -3.7163 0.0 0
M  V30 24 C 6.8471 -1.9836 0.0 0
M  V30 25 C 5.3056 -4.0987 0.0 0
M  V30 26 C 5.8075 0.3823 0.0 0
M  V30 27 C -1.3861 1.3144 0.0 0
M  V30 28 C -4.254 -4.8874 0.0 0
M  V30 29 C 6.9786 -0.454 0.0 0
M  V30 30 N 5.9389 1.9119 0.0 0
M  V30 31 C -2.0433 2.7245 0.0 0
M  V30 32 C -2.9157 1.5176 0.0 0
M  V30 33 C -0.5496 2.5572 0.0 0
M  V30 34 C -5.1622 -6.0584 0.0 0
M  V30 35 C -3.6685 -6.2257 0.0 0
M  V30 36 C -5.7836 -4.6842 0.0 0
M  V30 37 O -1.5295 11.5672 0.0 0
M  V30 38 C -0.1433 11.1251 0.0 0
M  V30 39 O 0.932 12.1528 0.0 0
M  V30 40 N 0.1314 9.6911 0.0 0
M  V30 41 C 0.5855 13.6584 0.0 0
M  V30 42 C -0.9081 8.6157 0.0 0
M  V30 43 C 1.4698 9.1056 0.0 0
M  V30 44 C 0.2389 15.1641 0.0 0
M  V30 45 C -0.8723 14.1723 0.0 0
M  V30 46 C 1.661 14.6861 0.0 0
M  V30 47 N -0.1911 7.349 0.0 0
M  V30 48 N -2.4377 8.8188 0.0 0
M  V30 49 C 2.8081 9.7628 0.0 0
M  V30 50 C 1.2666 7.6477 0.0 0
M  V30 51 C -3.3459 7.6477 0.0 0
M  V30 52 C -3.0949 10.2289 0.0 0
M  V30 53 C 3.9792 8.9264 0.0 0
M  V30 54 C 2.9396 11.2924 0.0 0
M  V30 55 C 2.4377 6.8113 0.0 0
M  V30 56 O -2.7603 6.3094 0.0 0
M  V30 57 O -4.8754 7.8509 0.0 0
M  V30 58 O -4.6245 10.432 0.0 0
M  V30 59 O -2.2584 11.4716 0.0 0
M  V30 60 C 5.3176 9.5836 0.0 0
M  V30 61 C 3.776 7.4685 0.0 0
M  V30 62 C 4.2779 11.9496 0.0 0
M  V30 63 C -5.7836 6.6798 0.0 0
M  V30 64 C -2.9157 12.8817 0.0 0
M  V30 65 C 5.449 11.1131 0.0 0
M  V30 66 N 4.4094 13.4792 0.0 0
M  V30 67 C -6.6918 5.5087 0.0 0
M  V30 68 C -5.1981 5.3415 0.0 0
M  V30 69 C -7.3131 6.883 0.0 0
M  V30 70 C -3.5729 14.2917 0.0 0
M  V30 71 C -4.4452 13.0848 0.0 0
M  V30 72 C -2.0792 14.1245 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 1 14 19
M  V30 19 2 15 20
M  V30 20 1 15 21
M  V30 21 2 16 22
M  V30 22 1 16 23
M  V30 23 2 17 24
M  V30 24 1 17 25
M  V30 25 1 18 26
M  V30 26 1 21 27
M  V30 27 1 23 28
M  V30 28 1 24 29
M  V30 29 1 26 30
M  V30 30 1 27 31
M  V30 31 1 27 32
M  V30 32 1 27 33
M  V30 33 1 28 34
M  V30 34 1 28 35
M  V30 35 1 28 36
M  V30 36 2 37 38
M  V30 37 1 38 39
M  V30 38 1 38 40
M  V30 39 1 39 41
M  V30 40 1 40 42
M  V30 41 1 40 43
M  V30 42 1 41 44
M  V30 43 1 41 45
M  V30 44 1 41 46
M  V30 45 2 42 47
M  V30 46 1 42 48
M  V30 47 1 43 49
M  V30 48 2 43 50
M  V30 49 1 48 51
M  V30 50 1 48 52
M  V30 51 2 49 53
M  V30 52 1 49 54
M  V30 53 1 50 55
M  V30 54 2 51 56
M  V30 55 1 51 57
M  V30 56 2 52 58
M  V30 57 1 52 59
M  V30 58 1 53 60
M  V30 59 1 53 61
M  V30 60 2 54 62
M  V30 61 1 57 63
M  V30 62 1 59 64
M  V30 63 2 60 65
M  V30 64 1 62 66
M  V30 65 1 63 67
M  V30 66 1 63 68
M  V30 67 1 63 69
M  V30 68 1 64 70
M  V30 69 1 64 71
M  V30 70 1 64 72
M  V30 71 1 11 14
M  V30 72 2 19 25
M  V30 73 2 26 29
M  V30 74 1 47 50
M  V30 75 1 55 61
M  V30 76 1 62 65
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00087001.cdx

>  <name>
US20220000118A1-20220106-C00066

>  <Row No>
211

$$$$
US20220000118A1-20220106-C00067
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 36 38 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.4316 -0.2767 0.0 0
M  V30 3 O 2.3941 0.8662 0.0 0
M  V30 4 N 1.8647 -1.6723 0.0 0
M  V30 5 C 1.8888 2.334 0.0 0
M  V30 6 C 0.9504 -2.8513 0.0 0
M  V30 7 C 3.2603 -2.1054 0.0 0
M  V30 8 C 1.3835 3.8017 0.0 0
M  V30 9 C 0.3849 2.6829 0.0 0
M  V30 10 C 2.8513 3.4769 0.0 0
M  V30 11 N 1.7926 -4.0303 0.0 0
M  V30 12 N -0.5895 -2.8152 0.0 0
M  V30 13 C 4.5236 -1.3354 0.0 0
M  V30 14 C 3.2242 -3.5731 0.0 0
M  V30 15 C -1.3715 -4.0784 0.0 0
M  V30 16 C -1.3715 -1.4798 0.0 0
M  V30 17 C 5.7868 -2.0693 0.0 0
M  V30 18 C 4.4875 0.2045 0.0 0
M  V30 19 C 4.4875 -4.307 0.0 0
M  V30 20 O -0.6496 -5.3417 0.0 0
M  V30 21 O -2.9114 -4.0424 0.0 0
M  V30 22 O -2.9114 -1.4437 0.0 0
M  V30 23 O -0.6376 -0.1443 0.0 0
M  V30 24 C 7.0501 -1.2993 0.0 0
M  V30 25 C 5.7508 -3.5371 0.0 0
M  V30 26 C 5.7508 0.9865 0.0 0
M  V30 27 C -3.6935 -5.3056 0.0 0
M  V30 28 C -1.4196 1.191 0.0 0
M  V30 29 N 8.3133 -2.0332 0.0 0
M  V30 30 C 7.014 0.2406 0.0 0
M  V30 31 C -4.4755 -6.5689 0.0 0
M  V30 32 C -2.9716 -6.5689 0.0 0
M  V30 33 C -5.2334 -5.2695 0.0 0
M  V30 34 C -2.1896 2.5265 0.0 0
M  V30 35 C -2.9596 1.2271 0.0 0
M  V30 36 C -0.6977 2.5265 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 1 14 19
M  V30 19 2 15 20
M  V30 20 1 15 21
M  V30 21 2 16 22
M  V30 22 1 16 23
M  V30 23 1 17 24
M  V30 24 1 17 25
M  V30 25 2 18 26
M  V30 26 1 21 27
M  V30 27 1 23 28
M  V30 28 1 24 29
M  V30 29 2 24 30
M  V30 30 1 27 31
M  V30 31 1 27 32
M  V30 32 1 27 33
M  V30 33 1 28 34
M  V30 34 1 28 35
M  V30 35 1 28 36
M  V30 36 1 11 14
M  V30 37 1 19 25
M  V30 38 1 26 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00088001.cdx

>  <name>
US20220000118A1-20220106-C00067

>  <Row No>
212

$$$$
US20220000118A1-20220106-C00068
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 16 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C 1.2666 0.7841 0.0 0 CFG=2
M  V30 3 C 2.5333 0.0482 0.0 0
M  V30 4 C 1.2304 2.3282 0.0 0
M  V30 5 O 2.4971 -1.4234 0.0 0
M  V30 6 C 3.7999 0.8323 0.0 0
M  V30 7 C 2.4971 3.1123 0.0 0
M  V30 8 C 3.7637 2.3764 0.0 0
M  V30 9 C 5.0666 0.0965 0.0 0
M  V30 10 C 5.0304 3.1606 0.0 0
M  V30 11 C 6.3332 0.8806 0.0 0
M  V30 12 N 4.9942 4.7047 0.0 0 CHG=1
M  V30 13 C 6.2971 2.4247 0.0 0
M  V30 14 O 6.2609 5.4888 0.0 0
M  V30 15 O 3.6552 5.4888 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=1
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 6 8
M  V30 8 1 6 9
M  V30 9 1 8 10
M  V30 10 2 9 11
M  V30 11 1 10 12
M  V30 12 2 10 13
M  V30 13 2 12 14
M  V30 14 1 12 15
M  V30 15 1 7 8
M  V30 16 1 11 13
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00089001.cdx

>  <name>
US20220000118A1-20220106-C00068

>  <Row No>
213

$$$$
US20220000118A1-20220106-C00069
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 O 8.2898 4.0019 0.0 0
M  V30 3 N 6.9558 3.2754 0.0 0 CHG=1
M  V30 4 O 5.6218 4.0615 0.0 0 CHG=-1
M  V30 5 C 6.92 1.8104 0.0 0
M  V30 6 C 5.586 1.0957 0.0 0
M  V30 7 C 8.1826 1.0957 0.0 0
M  V30 8 C 5.5503 -0.3692 0.0 0
M  V30 9 C 4.252 1.8699 0.0 0
M  V30 10 C 8.1468 -0.3692 0.0 0
M  V30 11 C 4.2163 -1.0838 0.0 0
M  V30 12 C 6.8128 -1.0838 0.0 0
M  V30 13 C 2.9181 1.1553 0.0 0
M  V30 14 N 3.8709 -2.5131 0.0 0
M  V30 15 C 2.8823 -0.3096 0.0 0
M  V30 16 C 2.3463 -2.6322 0.0 0
M  V30 17 N 1.7389 -1.2744 0.0 0
M  V30 18 N 1.4292 -3.8114 0.0 0
M  V30 19 C 0.2143 -1.0838 0.0 0
M  V30 20 C -0.0952 -3.6208 0.0 0
M  V30 21 C -0.7027 -2.263 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 2 3
M  V30 2 1 3 4
M  V30 3 1 3 5
M  V30 4 2 5 6
M  V30 5 1 5 7
M  V30 6 1 6 8
M  V30 7 1 6 9
M  V30 8 2 7 10
M  V30 9 1 8 11
M  V30 10 2 8 12
M  V30 11 1 9 13
M  V30 12 1 11 14
M  V30 13 2 11 15
M  V30 14 2 14 16
M  V30 15 1 15 17
M  V30 16 1 16 18
M  V30 17 1 17 19
M  V30 18 2 18 20
M  V30 19 2 19 21
M  V30 20 1 10 12
M  V30 21 1 13 15
M  V30 22 1 16 17
M  V30 23 1 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00090001.cdx

>  <name>
US20220000118A1-20220106-C00069

>  <Row No>
214

$$$$
US20220000118A1-20220106-C00070
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 38 40 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 N -0.0355 1.5188 0.0 0 CHG=1
M  V30 3 O 1.2103 2.2782 0.0 0 CHG=-1
M  V30 4 C -1.3527 2.2782 0.0 0
M  V30 5 C -2.6698 1.5663 0.0 0
M  V30 6 C -1.3883 3.7971 0.0 0
M  V30 7 C -3.9869 2.3376 0.0 0
M  V30 8 C -2.7054 0.1186 0.0 0
M  V30 9 C -2.7054 4.5565 0.0 0
M  V30 10 C -5.3041 1.6256 0.0 0
M  V30 11 C -4.0225 3.8564 0.0 0
M  V30 12 C -4.0225 -0.5933 0.0 0
M  V30 13 N -6.7517 2.124 0.0 0
M  V30 14 C -5.3397 0.1779 0.0 0
M  V30 15 C -7.6536 0.9611 0.0 0
M  V30 16 C -7.2501 3.5716 0.0 0
M  V30 17 N -6.7873 -0.2491 0.0 0
M  V30 18 N -9.1724 0.9967 0.0 0
M  V30 19 O -8.7334 3.9157 0.0 0
M  V30 20 O -6.3008 4.6989 0.0 0
M  V30 21 C -9.9318 -0.2491 0.0 0
M  V30 22 C -9.9318 2.3138 0.0 0
M  V30 23 C -6.7992 6.1466 0.0 0
M  V30 24 O -9.2199 -1.4951 0.0 0
M  V30 25 O -11.4507 -0.2135 0.0 0
M  V30 26 O -11.4507 2.3494 0.0 0
M  V30 27 O -9.2199 3.631 0.0 0
M  V30 28 C -7.2976 7.5942 0.0 0
M  V30 29 C -8.2825 6.4907 0.0 0
M  V30 30 C -5.8499 7.2738 0.0 0
M  V30 31 C -12.222 -1.4595 0.0 0
M  V30 32 C -9.9912 4.9481 0.0 0
M  V30 33 C -12.9933 -2.7054 0.0 0
M  V30 34 C -11.51 -2.7054 0.0 0
M  V30 35 C -13.7408 -1.4239 0.0 0
M  V30 36 C -10.7625 6.2652 0.0 0
M  V30 37 C -11.51 4.9837 0.0 0
M  V30 38 C -9.2792 6.2652 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 7 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 2 10 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 1 16 20
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 1 20 23
M  V30 23 2 21 24
M  V30 24 1 21 25
M  V30 25 2 22 26
M  V30 26 1 22 27
M  V30 27 1 23 28
M  V30 28 1 23 29
M  V30 29 1 23 30
M  V30 30 1 25 31
M  V30 31 1 27 32
M  V30 32 1 31 33
M  V30 33 1 31 34
M  V30 34 1 31 35
M  V30 35 1 32 36
M  V30 36 1 32 37
M  V30 37 1 32 38
M  V30 38 1 9 11
M  V30 39 1 12 14
M  V30 40 2 15 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00091001.cdx

>  <name>
US20220000118A1-20220106-C00070

>  <Row No>
215

$$$$
US20220000118A1-20220106-C00071
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 36 38 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.4316 -0.2767 0.0 0
M  V30 3 O 2.3941 0.8662 0.0 0
M  V30 4 N 1.8647 -1.6722 0.0 0
M  V30 5 C 1.8888 2.3339 0.0 0
M  V30 6 C 0.9504 -2.8513 0.0 0
M  V30 7 C 3.2603 -2.1054 0.0 0
M  V30 8 C 1.3835 3.8017 0.0 0
M  V30 9 C 0.3849 2.6828 0.0 0
M  V30 10 C 2.8513 3.4769 0.0 0
M  V30 11 N 1.7926 -4.0303 0.0 0
M  V30 12 N -0.5895 -2.8152 0.0 0
M  V30 13 C 4.5236 -1.3354 0.0 0
M  V30 14 C 3.2242 -3.5731 0.0 0
M  V30 15 C -1.3715 -4.0784 0.0 0
M  V30 16 C -1.3715 -1.4798 0.0 0
M  V30 17 C 5.7868 -2.0572 0.0 0
M  V30 18 C 4.4875 0.2045 0.0 0
M  V30 19 C 4.4875 -4.307 0.0 0
M  V30 20 O -0.6376 -5.3417 0.0 0
M  V30 21 O -2.9114 -4.0423 0.0 0
M  V30 22 O -2.9114 -1.4437 0.0 0
M  V30 23 O -0.6376 -0.1443 0.0 0
M  V30 24 C 7.0501 -1.2752 0.0 0
M  V30 25 C 5.7507 -3.525 0.0 0
M  V30 26 C 5.7507 0.9865 0.0 0
M  V30 27 C -3.6934 -5.3056 0.0 0
M  V30 28 C -1.4076 1.191 0.0 0
M  V30 29 N 8.3133 -1.9971 0.0 0
M  V30 30 C 7.014 0.2646 0.0 0
M  V30 31 C -4.4754 -6.5688 0.0 0
M  V30 32 C -2.9716 -6.5688 0.0 0
M  V30 33 C -5.2334 -5.2695 0.0 0
M  V30 34 C -2.1896 2.5264 0.0 0
M  V30 35 C -2.9475 1.2271 0.0 0
M  V30 36 C -0.6737 2.5264 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 7 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 1 14 19
M  V30 19 2 15 20
M  V30 20 1 15 21
M  V30 21 2 16 22
M  V30 22 1 16 23
M  V30 23 1 17 24
M  V30 24 1 17 25
M  V30 25 2 18 26
M  V30 26 1 21 27
M  V30 27 1 23 28
M  V30 28 1 24 29
M  V30 29 2 24 30
M  V30 30 1 27 31
M  V30 31 1 27 32
M  V30 32 1 27 33
M  V30 33 1 28 34
M  V30 34 1 28 35
M  V30 35 1 28 36
M  V30 36 1 11 14
M  V30 37 1 19 25
M  V30 38 1 26 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00092001.cdx

>  <name>
US20220000118A1-20220106-C00071

>  <Row No>
216

$$$$
US20220000118A1-20220106-C00072
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0358 -1.4586 0.0 0
M  V30 3 N -1.3629 -2.1759 0.0 0
M  V30 4 N 1.2194 -2.1759 0.0 0
M  V30 5 C -2.69 -1.3988 0.0 0
M  V30 6 C 2.4748 -1.3988 0.0 0
M  V30 7 C -4.0171 -2.1161 0.0 0
M  V30 8 C -2.7259 0.1315 0.0 0
M  V30 9 C 3.7302 -2.1161 0.0 0
M  V30 10 C 2.4389 0.1315 0.0 0
M  V30 11 C -5.3442 -1.339 0.0 0
M  V30 12 C -4.053 0.8966 0.0 0
M  V30 13 C 4.9855 -1.339 0.0 0
M  V30 14 C 3.6943 0.8966 0.0 0
M  V30 15 C -6.6713 -2.0564 0.0 0
M  V30 16 C -5.3801 0.1912 0.0 0
M  V30 17 C 4.9497 0.1912 0.0 0
M  V30 18 C -6.8626 -3.503 0.0 0
M  V30 19 C -8.0701 -1.3988 0.0 0
M  V30 20 N -8.3571 -3.778 0.0 0
M  V30 21 C -9.0983 -2.4629 0.0 0
M  V30 22 N -10.6167 -2.2716 0.0 0
M  V30 23 C 4.3997 -0.6695 0.0 0
M  V30 24 ? 5.8822 -0.6575 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 21 22
M  V30 22 1 23 24
M  V30 23 1 12 16
M  V30 24 1 14 17
M  V30 25 2 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00093001.cdx

>  <name>
US20220000118A1-20220106-C00072

>  <Row No>
217

$$$$
US20220000118A1-20220106-C00073
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4631 0.0 0
M  V30 3 N -1.3672 -2.1827 0.0 0
M  V30 4 N 1.2233 -2.1827 0.0 0
M  V30 5 C -2.6985 -1.4032 0.0 0
M  V30 6 C 1.1873 -3.6459 0.0 0
M  V30 7 C -4.0297 -2.1228 0.0 0
M  V30 8 C -2.7344 0.1319 0.0 0
M  V30 9 C -0.1439 -4.3775 0.0 0
M  V30 10 C 2.4466 -4.3775 0.0 0
M  V30 11 C -5.361 -1.3432 0.0 0
M  V30 12 C -4.0657 0.9114 0.0 0
M  V30 13 C -0.1799 -5.8407 0.0 0
M  V30 14 C 2.4106 -5.8407 0.0 0
M  V30 15 C -6.6923 -2.0628 0.0 0
M  V30 16 C -5.397 0.1918 0.0 0
M  V30 17 C 1.0794 -6.5603 0.0 0
M  V30 18 C -6.8842 -3.514 0.0 0
M  V30 19 C -8.0955 -1.4032 0.0 0
M  V30 20 C 1.0434 -8.0235 0.0 0
M  V30 21 N -8.3833 -3.7899 0.0 0
M  V30 22 C -9.1269 -2.4706 0.0 0
M  V30 23 C 2.3027 -8.7431 0.0 0
M  V30 24 N -10.6501 -2.2787 0.0 0
M  V30 25 C 3.562 -7.9636 0.0 0
M  V30 26 C 3.526 -6.4284 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 25 26
M  V30 26 1 12 16
M  V30 27 1 14 17
M  V30 28 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00096001.cdx

>  <name>
US20220000118A1-20220106-C00073

>  <Row No>
218

$$$$
US20220000118A1-20220106-C00074
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.464 0.0 0
M  V30 3 N -1.368 -2.184 0.0 0
M  V30 4 N 1.224 -2.184 0.0 0
M  V30 5 C -2.7 -1.404 0.0 0
M  V30 6 C 1.188 -3.648 0.0 0
M  V30 7 C -4.0321 -2.124 0.0 0
M  V30 8 C -2.736 0.132 0.0 0
M  V30 9 C -0.144 -4.3801 0.0 0
M  V30 10 C 2.448 -4.3801 0.0 0
M  V30 11 C -5.3641 -1.332 0.0 0
M  V30 12 C -4.0681 0.924 0.0 0
M  V30 13 C -0.18 -5.8441 0.0 0
M  V30 14 C 2.412 -5.8441 0.0 0
M  V30 15 C -6.6961 -2.052 0.0 0
M  V30 16 C -5.4001 0.204 0.0 0
M  V30 17 C 1.08 -6.5641 0.0 0
M  V30 18 C -6.8881 -3.504 0.0 0
M  V30 19 C -8.1002 -1.392 0.0 0
M  V30 20 C 1.044 -8.0282 0.0 0
M  V30 21 N -8.3882 -3.7801 0.0 0
M  V30 22 C -9.1322 -2.46 0.0 0
M  V30 23 C 2.304 -8.7482 0.0 0
M  V30 24 N -10.6562 -2.268 0.0 0
M  V30 25 C 3.564 -7.9682 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 12 16
M  V30 26 1 14 17
M  V30 27 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00097001.cdx

>  <name>
US20220000118A1-20220106-C00074

>  <Row No>
219

$$$$
US20220000118A1-20220106-C00075
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.309 0.7665 0.0 0
M  V30 3 C -2.618 0.0471 0.0 0
M  V30 4 C -1.3443 2.276 0.0 0
M  V30 5 Cl -2.6533 -1.3915 0.0 0
M  V30 6 C -3.927 0.8137 0.0 0
M  V30 7 C -2.6533 3.0425 0.0 0
M  V30 8 C -3.9624 2.3231 0.0 0
M  V30 9 N -2.6887 4.552 0.0 0
M  V30 10 C -3.9977 5.3185 0.0 0
M  V30 11 O -4.0331 6.828 0.0 0
M  V30 12 N -5.3067 4.5992 0.0 0
M  V30 13 C -6.6158 5.3657 0.0 0
M  V30 14 C -7.9248 4.6463 0.0 0
M  V30 15 C -6.6511 6.8752 0.0 0
M  V30 16 C -9.2338 5.4129 0.0 0
M  V30 17 C -7.9601 7.6417 0.0 0
M  V30 18 C -10.5428 4.6935 0.0 0
M  V30 19 C -9.2692 6.9224 0.0 0
M  V30 20 C -10.7315 3.2666 0.0 0
M  V30 21 C -11.9226 5.3421 0.0 0
M  V30 22 N -12.2056 2.9953 0.0 0
M  V30 23 C -12.9367 4.2926 0.0 0
M  V30 24 N -14.4344 4.4812 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 7 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00098001.cdx

>  <name>
US20220000118A1-20220106-C00075

>  <Row No>
220

$$$$
US20220000118A1-20220106-C00076
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0356 1.5191 0.0 0
M  V30 3 C 1.2105 2.2787 0.0 0
M  V30 4 C -1.3529 2.2787 0.0 0
M  V30 5 C 1.1749 3.7978 0.0 0
M  V30 6 C 2.4567 1.5666 0.0 0
M  V30 7 C -1.3886 3.7978 0.0 0
M  V30 8 C -0.1424 4.5693 0.0 0
M  V30 9 F 1.6853 0.3204 0.0 0
M  V30 10 F 3.7029 0.8426 0.0 0
M  V30 11 F 3.1688 2.884 0.0 0
M  V30 12 N -0.178 6.0884 0.0 0
M  V30 13 C -1.4954 6.848 0.0 0
M  V30 14 O -1.531 8.3672 0.0 0
M  V30 15 N -2.8128 6.1359 0.0 0
M  V30 16 C -4.1301 6.8955 0.0 0
M  V30 17 C -5.4475 6.1834 0.0 0
M  V30 18 C -4.1658 8.4146 0.0 0
M  V30 19 C -6.7649 6.943 0.0 0
M  V30 20 C -5.4831 9.1742 0.0 0
M  V30 21 C -8.0823 6.2309 0.0 0
M  V30 22 C -6.8005 8.4621 0.0 0
M  V30 23 C -8.2722 4.7948 0.0 0
M  V30 24 C -9.4709 6.8836 0.0 0
M  V30 25 N -9.7558 4.5218 0.0 0
M  V30 26 C -10.4916 5.8273 0.0 0
M  V30 27 N -11.9989 6.0172 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 8 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 26 27
M  V30 27 1 7 8
M  V30 28 1 20 22
M  V30 29 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00099001.cdx

>  <name>
US20220000118A1-20220106-C00076

>  <Row No>
221

$$$$
US20220000118A1-20220106-C00077
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 0.7117 1.3167 0.0 0
M  V30 3 F 1.9573 0.6049 0.0 0
M  V30 4 F 1.4235 2.6334 0.0 0
M  V30 5 C -0.6049 2.0759 0.0 0
M  V30 6 C -1.9217 1.3641 0.0 0
M  V30 7 C -0.6405 3.5943 0.0 0
M  V30 8 C -3.2384 2.1233 0.0 0
M  V30 9 C -1.9573 -0.083 0.0 0
M  V30 10 C -1.9573 4.3535 0.0 0
M  V30 11 C -3.274 3.6418 0.0 0
M  V30 12 C -0.7117 -0.7947 0.0 0
M  V30 13 N -1.9929 5.8719 0.0 0
M  V30 14 C -0.7473 -2.242 0.0 0
M  V30 15 C -3.3096 6.643 0.0 0
M  V30 16 O -3.3452 8.1614 0.0 0
M  V30 17 N -4.6264 5.9194 0.0 0
M  V30 18 C -5.9431 6.6904 0.0 0
M  V30 19 C -7.2598 5.9668 0.0 0
M  V30 20 C -5.9787 8.2088 0.0 0
M  V30 21 C -8.5766 6.7379 0.0 0
M  V30 22 C -7.2954 8.968 0.0 0
M  V30 23 C -9.8933 6.0143 0.0 0
M  V30 24 C -8.6122 8.2563 0.0 0
M  V30 25 C -10.0831 4.5789 0.0 0
M  V30 26 C -11.2812 6.6667 0.0 0
M  V30 27 N -11.566 4.3061 0.0 0
M  V30 28 C -12.3014 5.6109 0.0 0
M  V30 29 N -13.808 5.8007 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 2 7 10
M  V30 10 2 8 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 17 18
M  V30 18 2 18 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 2 20 22
M  V30 22 1 21 23
M  V30 23 2 21 24
M  V30 24 2 23 25
M  V30 25 1 23 26
M  V30 26 1 25 27
M  V30 27 1 26 28
M  V30 28 1 28 29
M  V30 29 1 10 11
M  V30 30 1 22 24
M  V30 31 2 27 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00100001.cdx

>  <name>
US20220000118A1-20220106-C00077

>  <Row No>
222

$$$$
US20220000118A1-20220106-C00078
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 0.7232 1.316 0.0 0
M  V30 3 F 1.9682 0.6046 0.0 0
M  V30 4 F 1.4465 2.6321 0.0 0
M  V30 5 C -0.5928 2.0749 0.0 0
M  V30 6 C -1.9089 1.3635 0.0 0
M  V30 7 C -0.6284 3.5925 0.0 0
M  V30 8 C -3.225 2.1223 0.0 0
M  V30 9 C -1.9444 -0.0829 0.0 0
M  V30 10 C -1.9444 4.3514 0.0 0
M  V30 11 C -3.2605 3.64 0.0 0
M  V30 12 C -0.6995 -0.7943 0.0 0
M  V30 13 N -1.98 5.869 0.0 0
M  V30 14 C -0.7351 -2.2409 0.0 0
M  V30 15 C -3.2961 6.6397 0.0 0
M  V30 16 O -3.3317 8.1574 0.0 0
M  V30 17 N -4.6122 5.9164 0.0 0
M  V30 18 C -5.9283 6.6871 0.0 0
M  V30 19 C -7.2444 5.9639 0.0 0
M  V30 20 C -5.9639 8.2048 0.0 0
M  V30 21 C -8.5605 6.7346 0.0 0
M  V30 22 C -7.28 8.9755 0.0 0
M  V30 23 C -9.8766 6.0113 0.0 0
M  V30 24 C -8.5961 8.2522 0.0 0
M  V30 25 C -10.0663 4.5766 0.0 0
M  V30 26 C -11.2638 6.6634 0.0 0
M  V30 27 N -11.5484 4.3039 0.0 0
M  V30 28 C -12.2835 5.6082 0.0 0
M  V30 29 N -13.7893 5.7979 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 2 7 10
M  V30 10 2 8 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 2 12 14
M  V30 14 1 13 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 17 18
M  V30 18 2 18 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 2 20 22
M  V30 22 1 21 23
M  V30 23 2 21 24
M  V30 24 2 23 25
M  V30 25 1 23 26
M  V30 26 1 25 27
M  V30 27 1 26 28
M  V30 28 1 28 29
M  V30 29 1 10 11
M  V30 30 1 22 24
M  V30 31 2 27 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00101001.cdx

>  <name>
US20220000118A1-20220106-C00078

>  <Row No>
223

$$$$
US20220000118A1-20220106-C00079
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C 1.2496 0.7616 0.0 0
M  V30 3 C 2.4992 0.0476 0.0 0
M  V30 4 C 1.2139 2.285 0.0 0
M  V30 5 C 3.7488 0.8092 0.0 0
M  V30 6 C 2.4635 3.0466 0.0 0
M  V30 7 Br 4.9984 0.0952 0.0 0
M  V30 8 C 3.7131 2.3326 0.0 0
M  V30 9 N 2.4278 4.57 0.0 0
M  V30 10 C 1.1067 5.3316 0.0 0
M  V30 11 O 1.071 6.855 0.0 0
M  V30 12 N -0.2142 4.6057 0.0 0
M  V30 13 C -1.5352 5.3792 0.0 0
M  V30 14 C -2.8562 4.6533 0.0 0
M  V30 15 C -1.5709 6.9026 0.0 0
M  V30 16 C -4.1772 5.4149 0.0 0
M  V30 17 C -2.8919 7.6761 0.0 0
M  V30 18 C -5.4982 4.689 0.0 0
M  V30 19 C -4.2129 6.9383 0.0 0
M  V30 20 C -5.6887 3.2489 0.0 0
M  V30 21 C -6.8907 5.3435 0.0 0
M  V30 22 N -7.1763 2.9752 0.0 0
M  V30 23 C -7.9142 4.2843 0.0 0
M  V30 24 N -9.4256 4.4748 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 6 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00102001.cdx

>  <name>
US20220000118A1-20220106-C00079

>  <Row No>
224

$$$$
US20220000118A1-20220106-C00080
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3123 0.7685 0.0 0
M  V30 3 C -2.6247 0.0472 0.0 0
M  V30 4 C -1.3478 2.2818 0.0 0
M  V30 5 C -3.9371 0.8158 0.0 0
M  V30 6 C -2.6602 -1.3951 0.0 0
M  V30 7 C -2.6602 3.0504 0.0 0
M  V30 8 C -3.9726 2.3291 0.0 0
M  V30 9 F -4.1736 -1.3596 0.0 0
M  V30 10 F -2.6957 -2.8375 0.0 0
M  V30 11 F -1.2177 -1.3596 0.0 0
M  V30 12 N -2.6957 4.5637 0.0 0
M  V30 13 C -4.008 5.3322 0.0 0
M  V30 14 O -4.0435 6.8456 0.0 0
M  V30 15 N -5.3204 4.611 0.0 0
M  V30 16 C -6.6328 5.3795 0.0 0
M  V30 17 C -7.9452 4.6583 0.0 0
M  V30 18 C -6.6683 6.8929 0.0 0
M  V30 19 C -9.2576 5.4268 0.0 0
M  V30 20 C -7.9807 7.6614 0.0 0
M  V30 21 C -10.5699 4.7056 0.0 0
M  V30 22 C -9.293 6.9402 0.0 0
M  V30 23 C -10.7591 3.275 0.0 0
M  V30 24 C -11.9533 5.3559 0.0 0
M  V30 25 N -12.237 3.0031 0.0 0
M  V30 26 C -12.9701 4.3036 0.0 0
M  V30 27 N -14.4716 4.4928 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 26 27
M  V30 27 1 7 8
M  V30 28 1 20 22
M  V30 29 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00103001.cdx

>  <name>
US20220000118A1-20220106-C00080

>  <Row No>
225

$$$$
US20220000118A1-20220106-C00081
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 32 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 0.711 1.3153 0.0 0
M  V30 3 F 1.9553 0.5925 0.0 0
M  V30 4 F 1.422 2.6307 0.0 0
M  V30 5 C -0.6043 2.0738 0.0 0
M  V30 6 C -1.9197 1.3627 0.0 0
M  V30 7 C -0.6399 3.5906 0.0 0
M  V30 8 C -3.2351 2.1212 0.0 0
M  V30 9 C -1.9553 -0.0829 0.0 0
M  V30 10 C -1.9553 4.349 0.0 0
M  V30 11 C -3.2706 3.638 0.0 0
M  V30 12 F -3.4721 -0.0474 0.0 0
M  V30 13 F -1.9908 -1.5286 0.0 0
M  V30 14 F -0.5095 -0.0474 0.0 0
M  V30 15 N -1.9908 5.8659 0.0 0
M  V30 16 C -3.3062 6.6361 0.0 0
M  V30 17 O -3.3417 8.153 0.0 0
M  V30 18 N -4.6216 5.9133 0.0 0
M  V30 19 C -5.937 6.6835 0.0 0
M  V30 20 C -7.2524 5.9607 0.0 0
M  V30 21 C -5.9725 8.2004 0.0 0
M  V30 22 C -8.5678 6.7309 0.0 0
M  V30 23 C -7.2879 8.9707 0.0 0
M  V30 24 C -9.8831 6.0081 0.0 0
M  V30 25 C -8.6033 8.2478 0.0 0
M  V30 26 C -10.0727 4.5742 0.0 0
M  V30 27 C -11.2696 6.6598 0.0 0
M  V30 28 N -11.554 4.3016 0.0 0
M  V30 29 C -12.2888 5.6052 0.0 0
M  V30 30 N -13.7938 5.7948 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 2 7 10
M  V30 10 2 8 11
M  V30 11 1 9 12
M  V30 12 1 9 13
M  V30 13 1 9 14
M  V30 14 1 10 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 18 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 2 21 23
M  V30 23 1 22 24
M  V30 24 2 22 25
M  V30 25 2 24 26
M  V30 26 1 24 27
M  V30 27 1 26 28
M  V30 28 1 27 29
M  V30 29 1 29 30
M  V30 30 1 10 11
M  V30 31 1 23 25
M  V30 32 2 28 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00104001.cdx

>  <name>
US20220000118A1-20220106-C00081

>  <Row No>
226

$$$$
US20220000118A1-20220106-C00082
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -1.3143 0.7578 0.0 0
M  V30 3 C -2.6286 0.0473 0.0 0
M  V30 4 C -1.3498 2.2734 0.0 0
M  V30 5 C -3.9429 0.8051 0.0 0
M  V30 6 C -2.6641 -1.3971 0.0 0
M  V30 7 C -2.6641 3.0312 0.0 0
M  V30 8 C -3.9784 2.3207 0.0 0
M  V30 9 F -4.1797 -1.3616 0.0 0
M  V30 10 F -2.6996 -2.8417 0.0 0
M  V30 11 F -1.2195 -1.3616 0.0 0
M  V30 12 N -2.6996 4.5468 0.0 0
M  V30 13 C -4.0139 5.3046 0.0 0
M  V30 14 O -4.0495 6.8202 0.0 0
M  V30 15 N -5.3282 4.5941 0.0 0
M  V30 16 C -6.6426 5.3519 0.0 0
M  V30 17 C -7.9569 4.6415 0.0 0
M  V30 18 C -6.6781 6.8675 0.0 0
M  V30 19 C -9.2712 5.3993 0.0 0
M  V30 20 C -7.9924 7.6372 0.0 0
M  V30 21 C -10.5855 4.6889 0.0 0
M  V30 22 C -9.3067 6.9149 0.0 0
M  V30 23 C -10.775 3.2561 0.0 0
M  V30 24 C -11.9709 5.3401 0.0 0
M  V30 25 N -12.255 2.9838 0.0 0
M  V30 26 C -12.9892 4.2863 0.0 0
M  V30 27 N -14.4929 4.4757 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 26 27
M  V30 27 1 7 8
M  V30 28 1 20 22
M  V30 29 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00105001.cdx

>  <name>
US20220000118A1-20220106-C00082

>  <Row No>
227

$$$$
US20220000118A1-20220106-C00083
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -1.3134 0.7573 0.0 0
M  V30 3 C -2.6268 0.0473 0.0 0
M  V30 4 C -1.3489 2.2719 0.0 0
M  V30 5 C -3.9403 0.8046 0.0 0
M  V30 6 C -2.6623 -1.3962 0.0 0
M  V30 7 C -2.6623 3.0292 0.0 0
M  V30 8 C -3.9758 2.3192 0.0 0
M  V30 9 F -4.177 -1.3607 0.0 0
M  V30 10 F -2.6978 -2.8398 0.0 0
M  V30 11 F -1.2187 -1.3607 0.0 0
M  V30 12 N -2.6978 4.5438 0.0 0
M  V30 13 C -4.0113 5.3011 0.0 0
M  V30 14 O -4.0468 6.8157 0.0 0
M  V30 15 N -5.3247 4.5793 0.0 0
M  V30 16 C -6.6382 5.3484 0.0 0
M  V30 17 C -7.9516 4.6266 0.0 0
M  V30 18 C -6.6737 6.863 0.0 0
M  V30 19 C -9.2651 5.3839 0.0 0
M  V30 20 C -7.9871 7.6321 0.0 0
M  V30 21 C -10.5785 4.6621 0.0 0
M  V30 22 C -9.3006 6.8985 0.0 0
M  V30 23 C -10.7679 3.2303 0.0 0
M  V30 24 C -11.963 5.3129 0.0 0
M  V30 25 N -12.247 2.9582 0.0 0
M  V30 26 C -12.9806 4.2598 0.0 0
M  V30 27 N -14.4834 4.4491 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 26 27
M  V30 27 1 7 8
M  V30 28 1 20 22
M  V30 29 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00106001.cdx

>  <name>
US20220000118A1-20220106-C00083

>  <Row No>
228

$$$$
US20220000118A1-20220106-C00084
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 1.2577 -0.7187 0.0 0
M  V30 3 C 2.5154 0.0479 0.0 0
M  V30 4 C 1.2217 -2.18 0.0 0
M  V30 5 N 2.4795 1.5811 0.0 0
M  V30 6 C 3.7731 -0.6707 0.0 0
M  V30 7 C 2.4795 -2.8987 0.0 0
M  V30 8 C 1.1499 2.3597 0.0 0
M  V30 9 F 5.0309 0.0958 0.0 0
M  V30 10 C 3.7372 -2.1321 0.0 0
M  V30 11 C 2.4435 -4.3601 0.0 0
M  V30 12 O 1.1139 3.8929 0.0 0
M  V30 13 N -0.1796 1.641 0.0 0
M  V30 14 F 0.9103 -4.3241 0.0 0
M  V30 15 F 2.4076 -5.8214 0.0 0
M  V30 16 F 3.9049 -4.3241 0.0 0
M  V30 17 C -1.5092 2.4196 0.0 0
M  V30 18 C -2.8388 1.7009 0.0 0
M  V30 19 C -1.5452 3.9528 0.0 0
M  V30 20 C -4.1684 2.4675 0.0 0
M  V30 21 C -2.8748 4.7194 0.0 0
M  V30 22 C -5.498 1.7488 0.0 0
M  V30 23 C -4.2044 4.0007 0.0 0
M  V30 24 C -5.6897 0.2994 0.0 0
M  V30 25 C -6.8995 2.4076 0.0 0
M  V30 26 N -7.187 0.0239 0.0 0
M  V30 27 C -7.9296 1.3415 0.0 0
M  V30 28 N -9.4509 1.5332 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 8 13
M  V30 13 1 11 14
M  V30 14 1 11 15
M  V30 15 1 11 16
M  V30 16 1 13 17
M  V30 17 2 17 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 2 19 21
M  V30 21 1 20 22
M  V30 22 2 20 23
M  V30 23 2 22 24
M  V30 24 1 22 25
M  V30 25 1 24 26
M  V30 26 1 25 27
M  V30 27 1 27 28
M  V30 28 1 7 10
M  V30 29 1 21 23
M  V30 30 2 26 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00107001.cdx

>  <name>
US20220000118A1-20220106-C00084

>  <Row No>
229

$$$$
US20220000118A1-20220106-C00085
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.3454 -1.4175 0.0 0
M  V30 3 C 0.7147 -2.3705 0.0 0
M  V30 4 C -1.7987 -1.8463 0.0 0
M  V30 5 F 2.0965 -1.8702 0.0 0
M  V30 6 C 0.3692 -3.788 0.0 0
M  V30 7 C -2.1441 -3.2639 0.0 0
M  V30 8 C -1.084 -4.2169 0.0 0
M  V30 9 N -3.5974 -3.6927 0.0 0
M  V30 10 C -4.7291 -2.6683 0.0 0
M  V30 11 O -4.4551 -1.1793 0.0 0
M  V30 12 N -6.1824 -3.0971 0.0 0
M  V30 13 C -7.314 -2.0727 0.0 0
M  V30 14 C -8.7673 -2.5015 0.0 0
M  V30 15 C -7.04 -0.5836 0.0 0
M  V30 16 C -9.899 -1.4771 0.0 0
M  V30 17 C -8.1717 0.4407 0.0 0
M  V30 18 C -11.3523 -1.9059 0.0 0
M  V30 19 C -9.625 0.0119 0.0 0
M  V30 20 C -11.8526 -3.2877 0.0 0
M  V30 21 C -12.5911 -1.0006 0.0 0
M  V30 22 N -13.3773 -3.252 0.0 0
M  V30 23 C -13.83 -1.8344 0.0 0
M  V30 24 N -15.2833 -1.3341 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 7 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00108001.cdx

>  <name>
US20220000118A1-20220106-C00085

>  <Row No>
230

$$$$
US20220000118A1-20220106-C00086
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.0355 1.5152 0.0 0
M  V30 3 C 1.2074 2.2846 0.0 0
M  V30 4 C -1.3494 2.2846 0.0 0
M  V30 5 Cl 2.4503 1.5625 0.0 0
M  V30 6 C 1.1719 3.7998 0.0 0
M  V30 7 C -1.3849 3.7998 0.0 0
M  V30 8 C -0.142 4.5574 0.0 0
M  V30 9 N -0.1775 6.0726 0.0 0
M  V30 10 C -1.4915 6.8302 0.0 0
M  V30 11 O -1.527 8.3454 0.0 0
M  V30 12 N -2.8055 6.12 0.0 0
M  V30 13 C -4.1194 6.8776 0.0 0
M  V30 14 C -5.4334 6.1673 0.0 0
M  V30 15 C -4.1549 8.3928 0.0 0
M  V30 16 C -6.7474 6.9249 0.0 0
M  V30 17 C -5.4689 9.1504 0.0 0
M  V30 18 C -8.0613 6.2147 0.0 0
M  V30 19 C -6.7829 8.4401 0.0 0
M  V30 20 C -8.2507 4.7823 0.0 0
M  V30 21 C -9.4463 6.8657 0.0 0
M  V30 22 N -9.7304 4.5101 0.0 0
M  V30 23 C -10.4644 5.8122 0.0 0
M  V30 24 N -11.9677 6.0016 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 7 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00109001.cdx

>  <name>
US20220000118A1-20220106-C00086

>  <Row No>
231

$$$$
US20220000118A1-20220106-C00087
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.0355 1.5152 0.0 0
M  V30 3 C -1.3494 2.2728 0.0 0
M  V30 4 C 1.2074 2.2728 0.0 0
M  V30 5 Cl -2.6634 1.5625 0.0 0
M  V30 6 C -1.385 3.788 0.0 0
M  V30 7 Cl 2.4503 1.5625 0.0 0
M  V30 8 C 1.1719 3.788 0.0 0
M  V30 9 C -0.142 4.5575 0.0 0
M  V30 10 N -0.1775 6.0727 0.0 0
M  V30 11 C -1.4915 6.8303 0.0 0
M  V30 12 O -1.527 8.3455 0.0 0
M  V30 13 N -2.8055 6.12 0.0 0
M  V30 14 C -4.1195 6.8776 0.0 0
M  V30 15 C -5.4334 6.1674 0.0 0
M  V30 16 C -4.155 8.3929 0.0 0
M  V30 17 C -6.7474 6.9368 0.0 0
M  V30 18 C -5.469 9.1623 0.0 0
M  V30 19 C -8.0614 6.2266 0.0 0
M  V30 20 C -6.7829 8.452 0.0 0
M  V30 21 C -8.2508 4.7942 0.0 0
M  V30 22 C -9.4464 6.8776 0.0 0
M  V30 23 N -9.7305 4.5219 0.0 0
M  V30 24 C -10.4645 5.8241 0.0 0
M  V30 25 N -11.9678 6.0135 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 6 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 2 11 12
M  V30 12 1 11 13
M  V30 13 1 13 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 2 19 21
M  V30 21 1 19 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 1 24 25
M  V30 25 1 8 9
M  V30 26 1 18 20
M  V30 27 2 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00110001.cdx

>  <name>
US20220000118A1-20220106-C00087

>  <Row No>
232

$$$$
US20220000118A1-20220106-C00088
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0355 1.5147 0.0 0
M  V30 3 C -1.3491 2.284 0.0 0
M  V30 4 C 1.2071 2.284 0.0 0
M  V30 5 Cl -2.6627 1.5621 0.0 0
M  V30 6 C -1.3846 3.7988 0.0 0
M  V30 7 Cl 2.4497 1.5621 0.0 0
M  V30 8 C 1.1716 3.7988 0.0 0
M  V30 9 C -0.142 4.5562 0.0 0
M  V30 10 N -0.1775 6.071 0.0 0
M  V30 11 C -1.4911 6.8284 0.0 0
M  V30 12 O -1.5266 8.3432 0.0 0
M  V30 13 N -2.8047 6.1183 0.0 0
M  V30 14 C -4.1183 6.8757 0.0 0
M  V30 15 C -5.4319 6.1657 0.0 0
M  V30 16 C -4.1538 8.3905 0.0 0
M  V30 17 C -6.7455 6.9231 0.0 0
M  V30 18 C -5.4674 9.1598 0.0 0
M  V30 19 C -8.0592 6.213 0.0 0
M  V30 20 C -6.781 8.4379 0.0 0
M  V30 21 C -8.2485 4.781 0.0 0
M  V30 22 C -9.4438 6.8639 0.0 0
M  V30 23 N -9.7278 4.5088 0.0 0
M  V30 24 C -10.4615 5.8106 0.0 0
M  V30 25 N -11.9645 6.0 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 6 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 2 11 12
M  V30 12 1 11 13
M  V30 13 1 13 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 2 19 21
M  V30 21 1 19 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 1 24 25
M  V30 25 1 8 9
M  V30 26 1 18 20
M  V30 27 2 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00111001.cdx

>  <name>
US20220000118A1-20220106-C00088

>  <Row No>
233

$$$$
US20220000118A1-20220106-C00089
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4638 0.0 0
M  V30 3 N -1.3678 -2.1957 0.0 0
M  V30 4 N 1.2238 -2.1957 0.0 0
M  V30 5 C -2.6997 -1.4038 0.0 0
M  V30 6 C 1.1878 -3.6596 0.0 0
M  V30 7 C -4.0315 -2.1357 0.0 0
M  V30 8 C -2.7357 0.1319 0.0 0
M  V30 9 C -0.1439 -4.3795 0.0 0
M  V30 10 C 2.4477 -4.3795 0.0 0
M  V30 11 C -5.3634 -1.3558 0.0 0
M  V30 12 C -4.0675 0.9119 0.0 0
M  V30 13 C -0.1799 -5.8433 0.0 0
M  V30 14 C 2.4117 -5.8433 0.0 0
M  V30 15 C -6.6952 -2.0877 0.0 0
M  V30 16 C -5.3994 0.1799 0.0 0
M  V30 17 C 1.0798 -6.5752 0.0 0
M  V30 18 C -6.8872 -3.5396 0.0 0
M  V30 19 C -8.0991 -1.4278 0.0 0
M  V30 20 O 1.0438 -8.0391 0.0 0
M  V30 21 N -8.3871 -3.8155 0.0 0
M  V30 22 C -9.131 -2.4957 0.0 0
M  V30 23 C 2.3037 -8.759 0.0 0
M  V30 24 N -10.6548 -2.3037 0.0 0
M  V30 25 C 2.2677 -10.2229 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 12 16
M  V30 26 1 14 17
M  V30 27 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00112001.cdx

>  <name>
US20220000118A1-20220106-C00089

>  <Row No>
234

$$$$
US20220000118A1-20220106-C00090
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 0.7235 1.3165 0.0 0
M  V30 3 F 1.9689 0.593 0.0 0
M  V30 4 F 1.4351 2.6331 0.0 0
M  V30 5 C -0.593 2.0756 0.0 0
M  V30 6 C -1.9096 1.364 0.0 0
M  V30 7 C -0.6286 3.5939 0.0 0
M  V30 8 O -1.9452 -0.083 0.0 0
M  V30 9 C -3.2262 2.1231 0.0 0
M  V30 10 C -1.9452 4.3648 0.0 0
M  V30 11 C -0.6998 -0.8065 0.0 0
M  V30 12 C -3.2617 3.6413 0.0 0
M  V30 13 N -1.9807 5.883 0.0 0
M  V30 14 C -0.7353 -2.2536 0.0 0
M  V30 15 C -3.2973 6.6421 0.0 0
M  V30 16 O -3.3329 8.1604 0.0 0
M  V30 17 N -4.6139 5.9305 0.0 0
M  V30 18 C -5.9305 6.6896 0.0 0
M  V30 19 C -7.2471 5.9779 0.0 0
M  V30 20 C -5.9661 8.2078 0.0 0
M  V30 21 C -8.5636 6.737 0.0 0
M  V30 22 C -7.2826 8.9788 0.0 0
M  V30 23 C -9.8802 6.0254 0.0 0
M  V30 24 C -8.5992 8.2553 0.0 0
M  V30 25 C -10.07 4.5902 0.0 0
M  V30 26 C -11.268 6.6777 0.0 0
M  V30 27 N -11.5526 4.3174 0.0 0
M  V30 28 C -12.288 5.6221 0.0 0
M  V30 29 N -13.7944 5.8119 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 2 7 10
M  V30 10 1 8 11
M  V30 11 2 9 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 13 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 17 18
M  V30 18 2 18 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 2 20 22
M  V30 22 1 21 23
M  V30 23 2 21 24
M  V30 24 2 23 25
M  V30 25 1 23 26
M  V30 26 1 25 27
M  V30 27 1 26 28
M  V30 28 1 28 29
M  V30 29 1 10 12
M  V30 30 1 22 24
M  V30 31 2 27 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00113001.cdx

>  <name>
US20220000118A1-20220106-C00090

>  <Row No>
235

$$$$
US20220000118A1-20220106-C00091
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -1.315 0.7582 0.0 0
M  V30 3 C -2.63 0.0473 0.0 0
M  V30 4 C -1.3505 2.2746 0.0 0
M  V30 5 C -3.9451 0.8056 0.0 0
M  V30 6 C -2.6656 -1.3979 0.0 0
M  V30 7 C -2.6656 3.0447 0.0 0
M  V30 8 C -3.9806 2.322 0.0 0
M  V30 9 C -1.4216 -2.1088 0.0 0
M  V30 10 N -2.7011 4.5611 0.0 0
M  V30 11 C -1.4572 -3.5541 0.0 0
M  V30 12 C -4.0161 5.3193 0.0 0
M  V30 13 O -4.0517 6.8358 0.0 0
M  V30 14 N -5.3312 4.6085 0.0 0
M  V30 15 C -6.6462 5.3786 0.0 0
M  V30 16 C -7.9613 4.6677 0.0 0
M  V30 17 C -6.6818 6.895 0.0 0
M  V30 18 C -9.2763 5.426 0.0 0
M  V30 19 C -7.9968 7.6532 0.0 0
M  V30 20 C -10.5913 4.7151 0.0 0
M  V30 21 C -9.3118 6.9424 0.0 0
M  V30 22 C -10.7809 3.2816 0.0 0
M  V30 23 C -11.9775 5.3667 0.0 0
M  V30 24 N -12.2618 3.0091 0.0 0
M  V30 25 C -12.9963 4.3123 0.0 0
M  V30 26 N -14.5009 4.5019 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 2 20 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 25 26
M  V30 26 1 7 8
M  V30 27 1 19 21
M  V30 28 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00114001.cdx

>  <name>
US20220000118A1-20220106-C00091

>  <Row No>
236

$$$$
US20220000118A1-20220106-C00092
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.315 0.7582 0.0 0
M  V30 3 C -2.63 0.0473 0.0 0
M  V30 4 C -1.3505 2.2746 0.0 0
M  V30 5 O -2.6656 -1.3979 0.0 0
M  V30 6 C -3.9451 0.8056 0.0 0
M  V30 7 C -2.6656 3.0447 0.0 0
M  V30 8 C -1.4216 -2.1088 0.0 0
M  V30 9 C -3.9806 2.322 0.0 0
M  V30 10 N -2.7011 4.5611 0.0 0
M  V30 11 C -1.4572 -3.5541 0.0 0
M  V30 12 C -4.0161 5.3193 0.0 0
M  V30 13 O -4.0517 6.8358 0.0 0
M  V30 14 N -5.3312 4.6085 0.0 0
M  V30 15 C -6.6462 5.3786 0.0 0
M  V30 16 C -7.9613 4.6677 0.0 0
M  V30 17 C -6.6818 6.895 0.0 0
M  V30 18 C -9.2763 5.426 0.0 0
M  V30 19 C -7.9968 7.6532 0.0 0
M  V30 20 C -10.5913 4.7151 0.0 0
M  V30 21 C -9.3118 6.9424 0.0 0
M  V30 22 C -10.7809 3.2816 0.0 0
M  V30 23 C -11.9775 5.3667 0.0 0
M  V30 24 N -12.2618 3.0091 0.0 0
M  V30 25 C -12.9963 4.3123 0.0 0
M  V30 26 N -14.5009 4.5019 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 10 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 2 20 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 25 26
M  V30 26 1 7 9
M  V30 27 1 19 21
M  V30 28 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00115001.cdx

>  <name>
US20220000118A1-20220106-C00092

>  <Row No>
237

$$$$
US20220000118A1-20220106-C00093
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3161 0.7588 0.0 0
M  V30 3 C -2.6323 0.0355 0.0 0
M  V30 4 C -1.3517 2.2766 0.0 0
M  V30 5 O -2.6679 -1.411 0.0 0
M  V30 6 C -3.9485 0.8063 0.0 0
M  V30 7 C -2.6679 3.0473 0.0 0
M  V30 8 C -1.4229 -2.1224 0.0 0
M  V30 9 C -3.9841 2.324 0.0 0
M  V30 10 N -2.7035 4.5651 0.0 0
M  V30 11 C -1.4584 -3.5691 0.0 0
M  V30 12 C -4.0196 5.324 0.0 0
M  V30 13 C -0.2134 -4.2924 0.0 0
M  V30 14 O -4.0552 6.8417 0.0 0
M  V30 15 N -5.3358 4.6125 0.0 0
M  V30 16 C -6.652 5.3833 0.0 0
M  V30 17 C -7.9682 4.6718 0.0 0
M  V30 18 C -6.6876 6.901 0.0 0
M  V30 19 C -9.2844 5.4425 0.0 0
M  V30 20 C -8.0038 7.6718 0.0 0
M  V30 21 C -10.6006 4.7311 0.0 0
M  V30 22 C -9.3199 6.9603 0.0 0
M  V30 23 C -10.7903 3.2963 0.0 0
M  V30 24 C -11.9879 5.3833 0.0 0
M  V30 25 N -12.2725 3.0236 0.0 0
M  V30 26 C -13.0076 4.3279 0.0 0
M  V30 27 N -14.5135 4.5177 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 2 12 14
M  V30 14 1 12 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 26 27
M  V30 27 1 7 9
M  V30 28 1 20 22
M  V30 29 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00116001.cdx

>  <name>
US20220000118A1-20220106-C00093

>  <Row No>
238

$$$$
US20220000118A1-20220106-C00094
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -1.3103 0.7555 0.0 0
M  V30 3 C -2.6207 0.0472 0.0 0
M  V30 4 C -1.3457 2.2665 0.0 0
M  V30 5 C -3.931 0.8027 0.0 0
M  V30 6 C -2.6561 -1.3929 0.0 0
M  V30 7 C -2.6561 3.0338 0.0 0
M  V30 8 C -3.9664 2.3137 0.0 0
M  V30 9 N -2.6915 4.5449 0.0 0
M  V30 10 C -4.0019 5.3122 0.0 0
M  V30 11 O -4.0373 6.8232 0.0 0
M  V30 12 N -5.3122 4.6039 0.0 0
M  V30 13 C -6.6226 5.3712 0.0 0
M  V30 14 C -7.9329 4.6629 0.0 0
M  V30 15 C -6.658 6.8823 0.0 0
M  V30 16 C -9.2433 5.4303 0.0 0
M  V30 17 C -7.9683 7.6496 0.0 0
M  V30 18 C -10.5536 4.722 0.0 0
M  V30 19 C -9.2787 6.9413 0.0 0
M  V30 20 C -10.7425 3.2935 0.0 0
M  V30 21 C -11.9348 5.3712 0.0 0
M  V30 22 N -12.2181 3.022 0.0 0
M  V30 23 C -12.9501 4.3206 0.0 0
M  V30 24 N -14.4493 4.5095 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 7 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00117001.cdx

>  <name>
US20220000118A1-20220106-C00094

>  <Row No>
239

$$$$
US20220000118A1-20220106-C00095
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 1.4459 0.0355 0.0 0
M  V30 3 F 1.4103 -1.4103 0.0 0
M  V30 4 F 2.8918 0.0711 0.0 0
M  V30 5 C 1.4103 1.5526 0.0 0
M  V30 6 C 0.0948 2.3229 0.0 0
M  V30 7 C 2.6548 2.3229 0.0 0
M  V30 8 C 0.0592 3.84 0.0 0
M  V30 9 C 2.6192 3.84 0.0 0
M  V30 10 C 1.3037 4.6104 0.0 0
M  V30 11 N 1.2681 6.1274 0.0 0
M  V30 12 C -0.0474 6.8978 0.0 0
M  V30 13 O -0.0829 8.4149 0.0 0
M  V30 14 N -1.3629 6.1748 0.0 0
M  V30 15 C -2.6785 6.9334 0.0 0
M  V30 16 C -3.9941 6.2104 0.0 0
M  V30 17 C -2.7141 8.4504 0.0 0
M  V30 18 C -5.3096 6.9689 0.0 0
M  V30 19 C -4.0296 9.2208 0.0 0
M  V30 20 C -6.6252 6.246 0.0 0
M  V30 21 C -5.3452 8.486 0.0 0
M  V30 22 C -6.8149 4.8119 0.0 0
M  V30 23 C -8.0119 6.8978 0.0 0
M  V30 24 N -8.2964 4.5393 0.0 0
M  V30 25 C -9.0312 5.843 0.0 0
M  V30 26 N -10.5364 6.0326 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 2 8 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 2 20 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 25 26
M  V30 26 1 9 10
M  V30 27 1 19 21
M  V30 28 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00118001.cdx

>  <name>
US20220000118A1-20220106-C00095

>  <Row No>
240

$$$$
US20220000118A1-20220106-C00096
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 0.7091 1.3119 0.0 0
M  V30 3 F 1.9502 0.6027 0.0 0
M  V30 4 F 1.4183 2.6239 0.0 0
M  V30 5 C -0.6027 2.0684 0.0 0
M  V30 6 C -0.6382 3.5813 0.0 0
M  V30 7 C -1.9147 1.3592 0.0 0
M  V30 8 C -1.9502 4.3495 0.0 0
M  V30 9 C -3.2267 2.1156 0.0 0
M  V30 10 N -1.9856 5.8624 0.0 0
M  V30 11 C -3.2621 3.6404 0.0 0
M  V30 12 C -3.2976 6.6189 0.0 0
M  V30 13 O -3.3331 8.1318 0.0 0
M  V30 14 N -4.6096 5.9097 0.0 0
M  V30 15 C -5.9215 6.6662 0.0 0
M  V30 16 C -7.2335 5.957 0.0 0
M  V30 17 C -5.957 8.1791 0.0 0
M  V30 18 C -8.5455 6.7134 0.0 0
M  V30 19 C -7.269 8.9355 0.0 0
M  V30 20 C -9.8574 6.0043 0.0 0
M  V30 21 C -8.5809 8.2263 0.0 0
M  V30 22 C -10.0465 4.5741 0.0 0
M  V30 23 C -11.2403 6.6543 0.0 0
M  V30 24 N -11.524 4.3023 0.0 0
M  V30 25 C -12.2568 5.6024 0.0 0
M  V30 26 N -13.7579 5.7915 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 8 10
M  V30 10 2 8 11
M  V30 11 1 10 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 2 20 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 25 26
M  V30 26 1 9 11
M  V30 27 1 19 21
M  V30 28 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00119001.cdx

>  <name>
US20220000118A1-20220106-C00096

>  <Row No>
241

$$$$
US20220000118A1-20220106-C00097
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4649 0.0 0
M  V30 3 N 1.2247 -2.1973 0.0 0
M  V30 4 N -1.3688 -2.1973 0.0 0
M  V30 5 C 1.1887 -3.6622 0.0 0
M  V30 6 C -2.7016 -1.4168 0.0 0
M  V30 7 C 2.4495 -4.3947 0.0 0
M  V30 8 C -0.144 -4.3947 0.0 0
M  V30 9 C -4.0345 -2.1493 0.0 0
M  V30 10 C -2.7377 0.12 0.0 0
M  V30 11 C 2.4135 -5.8596 0.0 0
M  V30 12 C 3.7103 -3.6142 0.0 0
M  V30 13 C -0.1801 -5.8596 0.0 0
M  V30 14 C -5.3673 -1.3568 0.0 0
M  V30 15 C -4.0705 0.9005 0.0 0
M  V30 16 C 1.0806 -6.5921 0.0 0
M  V30 17 C -6.7001 -2.0893 0.0 0
M  V30 18 C -5.4033 0.1801 0.0 0
M  V30 19 C 1.0446 -8.057 0.0 0
M  V30 20 C -6.8923 -3.5422 0.0 0
M  V30 21 C -8.105 -1.4288 0.0 0
M  V30 22 C 2.3054 -8.7894 0.0 0
M  V30 23 N -8.3932 -3.8183 0.0 0
M  V30 24 C -9.1377 -2.4975 0.0 0
M  V30 25 C 3.5662 -8.0089 0.0 0
M  V30 26 N -10.6626 -2.3054 0.0 0
M  V30 27 C 4.827 -8.7414 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 2 8 13
M  V30 13 1 9 14
M  V30 14 2 10 15
M  V30 15 2 11 16
M  V30 16 1 14 17
M  V30 17 2 14 18
M  V30 18 1 16 19
M  V30 19 2 17 20
M  V30 20 1 17 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 24 26
M  V30 26 1 25 27
M  V30 27 1 13 16
M  V30 28 1 15 18
M  V30 29 2 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00120001.cdx

>  <name>
US20220000118A1-20220106-C00097

>  <Row No>
242

$$$$
US20220000118A1-20220106-C00098
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 32 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3176 0.7597 0.0 0
M  V30 3 C -2.6353 0.0356 0.0 0
M  V30 4 C -1.3533 2.2792 0.0 0
M  V30 5 N -2.6709 -1.4126 0.0 0
M  V30 6 C -3.953 0.8072 0.0 0
M  V30 7 C -2.6709 3.0508 0.0 0
M  V30 8 C -1.4245 -2.1249 0.0 0
M  V30 9 C -3.9886 -2.1249 0.0 0
M  V30 10 C -3.9886 2.3267 0.0 0
M  V30 11 N -2.7066 4.5703 0.0 0
M  V30 12 C -1.4601 -3.5731 0.0 0
M  V30 13 C -4.0243 -3.5731 0.0 0
M  V30 14 C -4.0243 5.3301 0.0 0
M  V30 15 O -2.7778 -4.2973 0.0 0
M  V30 16 O -4.0599 6.8496 0.0 0
M  V30 17 N -5.3419 4.6178 0.0 0
M  V30 18 C -6.6596 5.3894 0.0 0
M  V30 19 C -7.9773 4.6772 0.0 0
M  V30 20 C -6.6952 6.9089 0.0 0
M  V30 21 C -9.295 5.4488 0.0 0
M  V30 22 C -8.0129 7.6805 0.0 0
M  V30 23 C -10.6127 4.7365 0.0 0
M  V30 24 C -9.3306 6.9683 0.0 0
M  V30 25 C -10.8026 3.3001 0.0 0
M  V30 26 C -12.0016 5.3894 0.0 0
M  V30 27 N -12.2865 3.0271 0.0 0
M  V30 28 C -13.0225 4.3329 0.0 0
M  V30 29 N -14.5302 4.5228 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 2 14 16
M  V30 16 1 14 17
M  V30 17 1 17 18
M  V30 18 2 18 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 2 20 22
M  V30 22 1 21 23
M  V30 23 2 21 24
M  V30 24 2 23 25
M  V30 25 1 23 26
M  V30 26 1 25 27
M  V30 27 1 26 28
M  V30 28 1 28 29
M  V30 29 1 7 10
M  V30 30 1 13 15
M  V30 31 1 22 24
M  V30 32 2 27 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00121001.cdx

>  <name>
US20220000118A1-20220106-C00098

>  <Row No>
243

$$$$
US20220000118A1-20220106-C00099
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3095 0.755 0.0 0
M  V30 3 C -2.6191 0.0471 0.0 0
M  V30 4 C -1.3449 2.2652 0.0 0
M  V30 5 O -2.6545 -1.3921 0.0 0
M  V30 6 C -3.9287 0.814 0.0 0
M  V30 7 C -2.6545 3.0321 0.0 0
M  V30 8 C -3.9641 2.3242 0.0 0
M  V30 9 N -2.6899 4.5422 0.0 0
M  V30 10 C -3.9995 5.3091 0.0 0
M  V30 11 O -4.0349 6.8192 0.0 0
M  V30 12 N -5.3091 4.5894 0.0 0
M  V30 13 C -6.6187 5.3563 0.0 0
M  V30 14 C -7.9283 4.6366 0.0 0
M  V30 15 C -6.6541 6.8664 0.0 0
M  V30 16 C -9.2379 5.4035 0.0 0
M  V30 17 C -7.9637 7.6333 0.0 0
M  V30 18 C -10.5474 4.6838 0.0 0
M  V30 19 C -9.2733 6.9136 0.0 0
M  V30 20 C -10.7362 3.2562 0.0 0
M  V30 21 C -11.9278 5.3327 0.0 0
M  V30 22 N -12.211 2.9849 0.0 0
M  V30 23 C -12.9425 4.2827 0.0 0
M  V30 24 N -14.4408 4.4714 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 7 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00122001.cdx

>  <name>
US20220000118A1-20220106-C00099

>  <Row No>
244

$$$$
US20220000118A1-20220106-C00100
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.464 0.0 0
M  V30 3 N 1.224 -2.196 0.0 0
M  V30 4 N -1.368 -2.196 0.0 0
M  V30 5 C 1.188 -3.66 0.0 0
M  V30 6 C -2.7 -1.404 0.0 0
M  V30 7 C 2.448 -4.392 0.0 0
M  V30 8 C -0.144 -4.392 0.0 0
M  V30 9 C -4.032 -2.136 0.0 0
M  V30 10 C -2.736 0.132 0.0 0
M  V30 11 C 2.412 -5.856 0.0 0
M  V30 12 C -0.18 -5.856 0.0 0
M  V30 13 C -5.364 -1.344 0.0 0
M  V30 14 C -4.068 0.912 0.0 0
M  V30 15 C 1.08 -6.588 0.0 0
M  V30 16 C 3.672 -6.588 0.0 0
M  V30 17 C -6.696 -2.076 0.0 0
M  V30 18 C -5.4 0.192 0.0 0
M  V30 19 C 1.044 -8.052 0.0 0
M  V30 20 C 3.636 -8.052 0.0 0
M  V30 21 C -6.888 -3.528 0.0 0
M  V30 22 C -8.1 -1.416 0.0 0
M  V30 23 C 2.304 -8.7841 0.0 0
M  V30 24 N -8.388 -3.804 0.0 0
M  V30 25 C -9.1321 -2.484 0.0 0
M  V30 26 N -10.6561 -2.292 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 11 15
M  V30 15 1 11 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 1 15 19
M  V30 19 1 16 20
M  V30 20 2 17 21
M  V30 21 1 17 22
M  V30 22 1 19 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 25 26
M  V30 26 1 12 15
M  V30 27 1 14 18
M  V30 28 1 20 23
M  V30 29 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00123001.cdx

>  <name>
US20220000118A1-20220106-C00100

>  <Row No>
245

$$$$
US20220000118A1-20220106-C00101
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4661 0.0 0
M  V30 3 N -1.37 -2.1872 0.0 0
M  V30 4 N 1.2258 -2.1872 0.0 0
M  V30 5 C -2.704 -1.4061 0.0 0
M  V30 6 C 1.1897 -3.6534 0.0 0
M  V30 7 C -4.038 -2.1271 0.0 0
M  V30 8 C -2.74 0.1321 0.0 0
M  V30 9 C 2.4516 -4.3865 0.0 0
M  V30 10 C -0.1442 -4.3865 0.0 0
M  V30 11 C -5.372 -1.346 0.0 0
M  V30 12 C -4.074 0.9133 0.0 0
M  V30 13 C 2.4156 -5.8527 0.0 0
M  V30 14 C -0.1802 -5.8527 0.0 0
M  V30 15 C -6.706 -2.067 0.0 0
M  V30 16 C -5.408 0.1922 0.0 0
M  V30 17 C 1.0816 -6.5738 0.0 0
M  V30 18 C 3.4852 -6.8141 0.0 0
M  V30 19 C -6.8983 -3.5212 0.0 0
M  V30 20 C -8.1121 -1.4061 0.0 0
M  V30 21 C 1.358 -8.0039 0.0 0
M  V30 22 C 2.8242 -8.1481 0.0 0
M  V30 23 N -8.4005 -3.7976 0.0 0
M  V30 24 C -9.1456 -2.4756 0.0 0
M  V30 25 N -10.6719 -2.2834 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 24 25
M  V30 25 1 12 16
M  V30 26 1 14 17
M  V30 27 1 21 22
M  V30 28 2 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00124001.cdx

>  <name>
US20220000118A1-20220106-C00101

>  <Row No>
246

$$$$
US20220000118A1-20220106-C00102
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3143 -0.7104 0.0 0
M  V30 3 C -1.3499 -2.1551 0.0 0
M  V30 4 C -2.6287 0.0592 0.0 0
M  V30 5 C -2.6643 -2.8656 0.0 0
M  V30 6 C -3.9431 -0.6512 0.0 0
M  V30 7 C -3.9787 -2.0959 0.0 0
M  V30 8 N -5.2931 -2.8064 0.0 0
M  V30 9 C -6.6075 -2.0248 0.0 0
M  V30 10 O -6.643 -0.5091 0.0 0
M  V30 11 N -7.9219 -2.7353 0.0 0
M  V30 12 C -9.2363 -1.9656 0.0 0
M  V30 13 C -10.5507 -2.6761 0.0 0
M  V30 14 C -9.2718 -0.4499 0.0 0
M  V30 15 C -11.865 -1.9064 0.0 0
M  V30 16 C -10.5862 0.3197 0.0 0
M  V30 17 C -13.1794 -2.6287 0.0 0
M  V30 18 C -11.9006 -0.3907 0.0 0
M  V30 19 C -13.3689 -4.0616 0.0 0
M  V30 20 C -14.5649 -1.9775 0.0 0
M  V30 21 N -14.8491 -4.3339 0.0 0
M  V30 22 C -15.5833 -3.0314 0.0 0
M  V30 23 N -17.0871 -2.8419 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 1 15 17
M  V30 17 2 15 18
M  V30 18 2 17 19
M  V30 19 1 17 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 22 23
M  V30 23 1 6 7
M  V30 24 1 16 18
M  V30 25 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00125001.cdx

>  <name>
US20220000118A1-20220106-C00102

>  <Row No>
247

$$$$
US20220000118A1-20220106-C00103
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4603 0.0 0
M  V30 3 N -1.3646 -2.1786 0.0 0
M  V30 4 N 1.2209 -2.1786 0.0 0
M  V30 5 C -2.6933 -1.4005 0.0 0
M  V30 6 C 1.185 -3.6389 0.0 0
M  V30 7 C -4.022 -2.1187 0.0 0
M  V30 8 C -2.7292 0.1316 0.0 0
M  V30 9 C -0.1436 -4.3572 0.0 0
M  V30 10 C 2.4419 -4.3572 0.0 0
M  V30 11 C -5.3507 -1.3406 0.0 0
M  V30 12 C -4.0579 0.9097 0.0 0
M  V30 13 C -0.1795 -5.8175 0.0 0
M  V30 14 C 2.406 -5.8175 0.0 0
M  V30 15 C -6.6794 -2.0588 0.0 0
M  V30 16 C -5.3866 0.1915 0.0 0
M  V30 17 C 1.0773 -6.5477 0.0 0
M  V30 18 C -6.8709 -3.5073 0.0 0
M  V30 19 C -8.0799 -1.4005 0.0 0
M  V30 20 N -8.3672 -3.7826 0.0 0
M  V30 21 C -9.1094 -2.4658 0.0 0
M  V30 22 N -10.6296 -2.2743 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 21 22
M  V30 22 1 12 16
M  V30 23 1 14 17
M  V30 24 2 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00126001.cdx

>  <name>
US20220000118A1-20220106-C00103

>  <Row No>
248

$$$$
US20220000118A1-20220106-C00104
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 0.709 1.3116 0.0 0
M  V30 3 F 1.9498 0.5908 0.0 0
M  V30 4 F 1.418 2.6233 0.0 0
M  V30 5 C -0.6026 2.0679 0.0 0
M  V30 6 C -0.6381 3.5805 0.0 0
M  V30 7 C -1.9143 1.3589 0.0 0
M  V30 8 C -1.9498 4.3486 0.0 0
M  V30 9 C -3.226 2.1152 0.0 0
M  V30 10 N -1.9852 5.8612 0.0 0
M  V30 11 C -3.2615 3.6278 0.0 0
M  V30 12 C -4.5377 1.4062 0.0 0
M  V30 13 C -3.2969 6.6293 0.0 0
M  V30 14 O -3.3324 8.1419 0.0 0
M  V30 15 N -4.6086 5.9203 0.0 0
M  V30 16 C -5.9203 6.6766 0.0 0
M  V30 17 C -7.232 5.9676 0.0 0
M  V30 18 C -5.9558 8.1892 0.0 0
M  V30 19 C -8.5437 6.7357 0.0 0
M  V30 20 C -7.2675 8.9573 0.0 0
M  V30 21 C -9.8554 6.0267 0.0 0
M  V30 22 C -8.5792 8.2483 0.0 0
M  V30 23 C -10.0445 4.5968 0.0 0
M  V30 24 C -11.238 6.6766 0.0 0
M  V30 25 N -11.5216 4.325 0.0 0
M  V30 26 C -12.2543 5.6249 0.0 0
M  V30 27 N -13.755 5.814 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 8 10
M  V30 10 2 8 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 26 27
M  V30 27 1 9 11
M  V30 28 1 20 22
M  V30 29 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00127001.cdx

>  <name>
US20220000118A1-20220106-C00104

>  <Row No>
249

$$$$
US20220000118A1-20220106-C00105
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.2493 0.7615 0.0 0
M  V30 3 C 2.4987 0.0475 0.0 0
M  V30 4 C 1.2136 2.2845 0.0 0
M  V30 5 C 3.7481 0.821 0.0 0
M  V30 6 C 2.463 3.058 0.0 0
M  V30 7 Cl 4.9975 0.107 0.0 0
M  V30 8 C 3.7124 2.344 0.0 0
M  V30 9 N 2.4273 4.581 0.0 0
M  V30 10 C 1.1065 5.3426 0.0 0
M  V30 11 O 1.0709 6.8656 0.0 0
M  V30 12 N -0.2141 4.6167 0.0 0
M  V30 13 C -1.5349 5.3783 0.0 0
M  V30 14 C -2.8557 4.6524 0.0 0
M  V30 15 C -1.5706 6.9013 0.0 0
M  V30 16 C -4.1765 5.4259 0.0 0
M  V30 17 C -2.8914 7.6747 0.0 0
M  V30 18 C -5.4972 4.7 0.0 0
M  V30 19 C -4.2122 6.9489 0.0 0
M  V30 20 C -5.6876 3.2603 0.0 0
M  V30 21 C -6.8894 5.3545 0.0 0
M  V30 22 N -7.175 2.9866 0.0 0
M  V30 23 C -7.9127 4.2955 0.0 0
M  V30 24 N -9.4358 4.3312 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 6 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00128001.cdx

>  <name>
US20220000118A1-20220106-C00105

>  <Row No>
250

$$$$
US20220000118A1-20220106-C00106
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -1.3097 0.7669 0.0 0
M  V30 3 C -2.6195 0.0471 0.0 0
M  V30 4 C -1.3451 2.2773 0.0 0
M  V30 5 Br -2.6549 -1.3923 0.0 0
M  V30 6 C -3.9292 0.8141 0.0 0
M  V30 7 C -2.6549 3.0442 0.0 0
M  V30 8 C -3.9646 2.3245 0.0 0
M  V30 9 N -2.6903 4.5546 0.0 0
M  V30 10 C -4.0 5.3216 0.0 0
M  V30 11 O -4.0354 6.8319 0.0 0
M  V30 12 N -5.3098 4.6136 0.0 0
M  V30 13 C -6.6195 5.3806 0.0 0
M  V30 14 C -7.9293 4.6726 0.0 0
M  V30 15 C -6.6549 6.8909 0.0 0
M  V30 16 C -9.239 5.4396 0.0 0
M  V30 17 C -7.9647 7.6579 0.0 0
M  V30 18 C -10.5488 4.7316 0.0 0
M  V30 19 C -9.2744 6.9499 0.0 0
M  V30 20 C -10.7376 3.3038 0.0 0
M  V30 21 C -11.9294 5.3806 0.0 0
M  V30 22 N -12.2125 3.0324 0.0 0
M  V30 23 C -12.9441 4.3304 0.0 0
M  V30 24 N -14.4545 4.3658 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 7 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00129001.cdx

>  <name>
US20220000118A1-20220106-C00106

>  <Row No>
251

$$$$
US20220000118A1-20220106-C00107
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3097 0.7669 0.0 0
M  V30 3 C -2.6195 0.0471 0.0 0
M  V30 4 C -1.3451 2.2773 0.0 0
M  V30 5 C -3.9292 0.8141 0.0 0
M  V30 6 C -2.6549 -1.3923 0.0 0
M  V30 7 C -2.6549 3.0442 0.0 0
M  V30 8 C -3.9646 2.3245 0.0 0
M  V30 9 N -2.6903 4.5546 0.0 0
M  V30 10 C -4.0 5.3216 0.0 0
M  V30 11 O -4.0354 6.8319 0.0 0
M  V30 12 N -5.3098 4.6136 0.0 0
M  V30 13 C -6.6195 5.3806 0.0 0
M  V30 14 C -7.9293 4.6726 0.0 0
M  V30 15 C -6.6549 6.8909 0.0 0
M  V30 16 C -9.239 5.4396 0.0 0
M  V30 17 C -7.9647 7.6579 0.0 0
M  V30 18 C -10.5488 4.7316 0.0 0
M  V30 19 C -9.2744 6.9499 0.0 0
M  V30 20 C -10.7376 3.3038 0.0 0
M  V30 21 C -11.9294 5.3806 0.0 0
M  V30 22 N -12.2125 3.0324 0.0 0
M  V30 23 C -12.9441 4.3304 0.0 0
M  V30 24 N -14.4545 4.3658 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 7 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00130001.cdx

>  <name>
US20220000118A1-20220106-C00107

>  <Row No>
252

$$$$
US20220000118A1-20220106-C00108
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 0.7101 1.3137 0.0 0
M  V30 3 F 1.9527 0.6035 0.0 0
M  V30 4 F 1.4202 2.6274 0.0 0
M  V30 5 C -0.6035 2.0711 0.0 0
M  V30 6 C -1.9172 1.361 0.0 0
M  V30 7 C -0.639 3.586 0.0 0
M  V30 8 C -3.2309 2.1184 0.0 0
M  V30 9 C -1.9527 -0.0828 0.0 0
M  V30 10 C -1.9527 4.3553 0.0 0
M  V30 11 C -3.2664 3.6333 0.0 0
M  V30 12 N -1.9883 5.8702 0.0 0
M  V30 13 C -3.302 6.6276 0.0 0
M  V30 14 O -3.3375 8.1425 0.0 0
M  V30 15 N -4.6157 5.9175 0.0 0
M  V30 16 C -5.9294 6.6868 0.0 0
M  V30 17 C -7.2431 5.9767 0.0 0
M  V30 18 C -5.9649 8.2017 0.0 0
M  V30 19 C -8.5568 6.7341 0.0 0
M  V30 20 C -7.2786 8.9592 0.0 0
M  V30 21 C -9.8705 6.024 0.0 0
M  V30 22 C -8.5923 8.249 0.0 0
M  V30 23 C -10.0598 4.592 0.0 0
M  V30 24 C -11.2552 6.675 0.0 0
M  V30 25 N -11.5392 4.3198 0.0 0
M  V30 26 C -12.273 5.6216 0.0 0
M  V30 27 N -13.7879 5.6571 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 2 7 10
M  V30 10 2 8 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 26 27
M  V30 27 1 10 11
M  V30 28 1 20 22
M  V30 29 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00131001.cdx

>  <name>
US20220000118A1-20220106-C00108

>  <Row No>
253

$$$$
US20220000118A1-20220106-C00109
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.0357 -1.4551 0.0 0
M  V30 3 C -1.3597 -2.1708 0.0 0
M  V30 4 C 1.2166 -2.1708 0.0 0
M  V30 5 C -1.3955 -3.6259 0.0 0
M  V30 6 C 1.1808 -3.6259 0.0 0
M  V30 7 N -2.7194 -4.3535 0.0 0
M  V30 8 C -0.1431 -4.3535 0.0 0
M  V30 9 C -4.0434 -3.5901 0.0 0
M  V30 10 F -0.1789 -5.8087 0.0 0
M  V30 11 O -4.0792 -2.0634 0.0 0
M  V30 12 N -5.3673 -4.3177 0.0 0
M  V30 13 C -6.6913 -3.5544 0.0 0
M  V30 14 C -8.0152 -4.2819 0.0 0
M  V30 15 C -6.7271 -2.0276 0.0 0
M  V30 16 C -9.3392 -3.5066 0.0 0
M  V30 17 C -8.051 -1.2643 0.0 0
M  V30 18 C -10.6632 -4.2342 0.0 0
M  V30 19 C -9.375 -1.9799 0.0 0
M  V30 20 C -10.854 -5.6774 0.0 0
M  V30 21 C -12.0587 -3.5782 0.0 0
M  V30 22 N -12.3449 -5.9518 0.0 0
M  V30 23 C -13.0844 -4.6398 0.0 0
M  V30 24 N -14.5992 -4.4489 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 2 9 11
M  V30 11 1 9 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 6 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00132001.cdx

>  <name>
US20220000118A1-20220106-C00109

>  <Row No>
254

$$$$
US20220000118A1-20220106-C00110
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4618 0.0 0
M  V30 3 N -1.366 -2.1808 0.0 0
M  V30 4 N 1.2222 -2.1808 0.0 0
M  V30 5 C -2.6961 -1.4019 0.0 0
M  V30 6 C 1.1862 -3.6427 0.0 0
M  V30 7 C -4.0262 -2.1209 0.0 0
M  V30 8 C -2.732 0.1318 0.0 0
M  V30 9 C -0.1437 -4.3617 0.0 0
M  V30 10 C 2.4444 -4.3617 0.0 0
M  V30 11 C -5.3562 -1.342 0.0 0
M  V30 12 C -4.0621 0.9106 0.0 0
M  V30 13 C -0.1797 -5.8236 0.0 0
M  V30 14 C 2.4085 -5.8236 0.0 0
M  V30 15 C -6.6863 -2.061 0.0 0
M  V30 16 C -5.3922 0.1917 0.0 0
M  V30 17 C 1.0784 -6.5545 0.0 0
M  V30 18 C -6.878 -3.5109 0.0 0
M  V30 19 C -8.0883 -1.4019 0.0 0
M  V30 20 C 1.0424 -8.0164 0.0 0
M  V30 21 N -8.3759 -3.7865 0.0 0
M  V30 22 C -9.1188 -2.4684 0.0 0
M  V30 23 N -10.6526 -2.4324 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 22 23
M  V30 23 1 12 16
M  V30 24 1 14 17
M  V30 25 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00133001.cdx

>  <name>
US20220000118A1-20220106-C00110

>  <Row No>
255

$$$$
US20220000118A1-20220106-C00111
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4642 0.0 0
M  V30 3 N -1.3682 -2.1843 0.0 0
M  V30 4 N 1.2242 -2.1843 0.0 0
M  V30 5 C -2.7004 -1.4042 0.0 0
M  V30 6 C 1.1881 -3.6486 0.0 0
M  V30 7 C -4.0326 -2.1243 0.0 0
M  V30 8 C -2.7364 0.132 0.0 0
M  V30 9 C -0.144 -4.3687 0.0 0
M  V30 10 C 2.4484 -4.3687 0.0 0
M  V30 11 C -5.3648 -1.3442 0.0 0
M  V30 12 C -4.0686 0.9121 0.0 0
M  V30 13 C -0.18 -5.8329 0.0 0
M  V30 14 C 2.4124 -5.8329 0.0 0
M  V30 15 C -6.6971 -2.0643 0.0 0
M  V30 16 C -5.4009 0.192 0.0 0
M  V30 17 C 1.0801 -6.553 0.0 0
M  V30 18 C -6.8891 -3.5165 0.0 0
M  V30 19 C -8.1013 -1.4042 0.0 0
M  V30 20 C 1.0441 -8.0173 0.0 0
M  V30 21 N -8.3894 -3.7926 0.0 0
M  V30 22 C -9.1335 -2.4724 0.0 0
M  V30 23 C 2.3043 -8.7374 0.0 0
M  V30 24 N -10.6697 -2.4364 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 12 16
M  V30 25 1 14 17
M  V30 26 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00134001.cdx

>  <name>
US20220000118A1-20220106-C00111

>  <Row No>
256

$$$$
US20220000118A1-20220106-C00112
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 32 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0361 -1.469 0.0 0
M  V30 3 N -1.3727 -2.2035 0.0 0
M  V30 4 N 1.2282 -2.2035 0.0 0
M  V30 5 C -2.7092 -1.4208 0.0 0
M  V30 6 C 1.192 -3.6725 0.0 0
M  V30 7 C -4.0458 -2.1553 0.0 0
M  V30 8 C -2.7454 0.1204 0.0 0
M  V30 9 C -0.1444 -4.395 0.0 0
M  V30 10 C 2.4564 -4.395 0.0 0
M  V30 11 C -5.3824 -1.3727 0.0 0
M  V30 12 C -4.0819 0.903 0.0 0
M  V30 13 C -0.1806 -5.864 0.0 0
M  V30 14 C 2.4202 -5.864 0.0 0
M  V30 15 C -6.719 -2.1072 0.0 0
M  V30 16 C -5.4185 0.1685 0.0 0
M  V30 17 C 1.0837 -6.5865 0.0 0
M  V30 18 C -6.9116 -3.5642 0.0 0
M  V30 19 C -8.1278 -1.4449 0.0 0
M  V30 20 C 1.0475 -8.0556 0.0 0
M  V30 21 N -8.4168 -3.8411 0.0 0
M  V30 22 C -9.1634 -2.5166 0.0 0
M  V30 23 C 2.3119 -8.7901 0.0 0
M  V30 24 N -10.7046 -2.4805 0.0 0
M  V30 25 C 2.2758 -10.2591 0.0 0
M  V30 26 C 3.5762 -8.0074 0.0 0
M  V30 27 C 3.5401 -10.9936 0.0 0
M  V30 28 C 4.8405 -8.7419 0.0 0
M  V30 29 C 4.8044 -10.2109 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 2 23 25
M  V30 25 1 23 26
M  V30 26 1 25 27
M  V30 27 2 26 28
M  V30 28 2 27 29
M  V30 29 1 12 16
M  V30 30 1 14 17
M  V30 31 2 21 22
M  V30 32 1 28 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00135001.cdx

>  <name>
US20220000118A1-20220106-C00112

>  <Row No>
257

$$$$
US20220000118A1-20220106-C00113
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4638 0.0 0
M  V30 3 N 1.2238 -2.1837 0.0 0
M  V30 4 N -1.3678 -2.1837 0.0 0
M  V30 5 C 1.1878 -3.6475 0.0 0
M  V30 6 C -2.6996 -1.4038 0.0 0
M  V30 7 C 2.4476 -4.3794 0.0 0
M  V30 8 C -0.1439 -4.3794 0.0 0
M  V30 9 C -4.0314 -2.1237 0.0 0
M  V30 10 C -2.7356 0.1319 0.0 0
M  V30 11 C 2.4116 -5.8432 0.0 0
M  V30 12 C -0.1799 -5.8432 0.0 0
M  V30 13 C -5.3632 -1.3438 0.0 0
M  V30 14 C -4.0674 0.9118 0.0 0
M  V30 15 C 1.0798 -6.5631 0.0 0
M  V30 16 C 3.6715 -6.5631 0.0 0
M  V30 17 C -6.6951 -2.0637 0.0 0
M  V30 18 C -5.3992 0.1919 0.0 0
M  V30 19 C 1.0438 -8.0269 0.0 0
M  V30 20 C -6.887 -3.5155 0.0 0
M  V30 21 C -8.0989 -1.4038 0.0 0
M  V30 22 N -8.3868 -3.7914 0.0 0
M  V30 23 C -9.1307 -2.4716 0.0 0
M  V30 24 N -10.6665 -2.4356 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 11 15
M  V30 15 1 11 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 1 15 19
M  V30 19 2 17 20
M  V30 20 1 17 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 12 15
M  V30 25 1 14 18
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00136001.cdx

>  <name>
US20220000118A1-20220106-C00113

>  <Row No>
258

$$$$
US20220000118A1-20220106-C00114
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4639 0.0 0
M  V30 3 N -1.3679 -2.1959 0.0 0
M  V30 4 N 1.2239 -2.1959 0.0 0
M  V30 5 C -2.6999 -1.4159 0.0 0
M  V30 6 C 1.1879 -3.6599 0.0 0
M  V30 7 C -4.0319 -2.1479 0.0 0
M  V30 8 C -2.7359 0.1199 0.0 0
M  V30 9 C -0.1439 -4.3798 0.0 0
M  V30 10 C 2.4479 -4.3798 0.0 0
M  V30 11 C -5.3638 -1.3679 0.0 0
M  V30 12 C -4.0679 0.8999 0.0 0
M  V30 13 C -0.1799 -5.8438 0.0 0
M  V30 14 C 2.4119 -5.8438 0.0 0
M  V30 15 C -6.6958 -2.0999 0.0 0
M  V30 16 C -5.3998 0.1679 0.0 0
M  V30 17 C 1.0799 -6.5638 0.0 0
M  V30 18 C -6.8878 -3.5519 0.0 0
M  V30 19 C -8.0998 -1.4399 0.0 0
M  V30 20 C 1.0439 -8.0278 0.0 0
M  V30 21 N -8.3877 -3.8279 0.0 0
M  V30 22 C -9.1317 -2.5079 0.0 0
M  V30 23 C 2.3039 -8.7477 0.0 0
M  V30 24 C -0.2879 -8.7477 0.0 0
M  V30 25 C 1.0079 -9.4917 0.0 0
M  V30 26 N -10.6677 -2.4719 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 20 24
M  V30 24 1 20 25
M  V30 25 1 22 26
M  V30 26 1 12 16
M  V30 27 1 14 17
M  V30 28 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00137001.cdx

>  <name>
US20220000118A1-20220106-C00114

>  <Row No>
259

$$$$
US20220000118A1-20220106-C00115
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.463 0.0 0
M  V30 3 N 1.2232 -2.1826 0.0 0
M  V30 4 N -1.3671 -2.1826 0.0 0
M  V30 5 C 1.1872 -3.6457 0.0 0
M  V30 6 C -2.6983 -1.4031 0.0 0
M  V30 7 C 2.4464 -4.3652 0.0 0
M  V30 8 C -0.1439 -4.3652 0.0 0
M  V30 9 C -4.0295 -2.1226 0.0 0
M  V30 10 C -2.7343 0.1319 0.0 0
M  V30 11 C 2.4105 -5.8283 0.0 0
M  V30 12 C 3.7057 -3.5857 0.0 0
M  V30 13 C -0.1798 -5.8283 0.0 0
M  V30 14 C -5.3606 -1.3431 0.0 0
M  V30 15 C -4.0654 0.9114 0.0 0
M  V30 16 C 1.0793 -6.5479 0.0 0
M  V30 17 C -6.6918 -2.0627 0.0 0
M  V30 18 C -5.3966 0.1918 0.0 0
M  V30 19 C 1.0433 -8.011 0.0 0
M  V30 20 C -6.8837 -3.5138 0.0 0
M  V30 21 C -8.0949 -1.4031 0.0 0
M  V30 22 N -8.3828 -3.7896 0.0 0
M  V30 23 C -9.1263 -2.4704 0.0 0
M  V30 24 N -10.6613 -2.4344 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 2 8 13
M  V30 13 1 9 14
M  V30 14 2 10 15
M  V30 15 2 11 16
M  V30 16 1 14 17
M  V30 17 2 14 18
M  V30 18 1 16 19
M  V30 19 2 17 20
M  V30 20 1 17 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 13 16
M  V30 25 1 15 18
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00138001.cdx

>  <name>
US20220000118A1-20220106-C00115

>  <Row No>
260

$$$$
US20220000118A1-20220106-C00116
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4609 0.0 0
M  V30 3 N 1.2214 -2.1914 0.0 0
M  V30 4 N -1.3651 -2.1914 0.0 0
M  V30 5 C 1.1855 -3.6523 0.0 0
M  V30 6 C -2.6943 -1.413 0.0 0
M  V30 7 C 2.4428 -4.3708 0.0 0
M  V30 8 C -0.1436 -4.3708 0.0 0
M  V30 9 C -4.0235 -2.1435 0.0 0
M  V30 10 C -2.7302 0.1197 0.0 0
M  V30 11 C 2.4069 -5.8317 0.0 0
M  V30 12 C 3.7002 -3.5924 0.0 0
M  V30 13 C -0.1796 -5.8317 0.0 0
M  V30 14 C -1.4729 -3.5924 0.0 0
M  V30 15 C -5.3527 -1.3651 0.0 0
M  V30 16 C -4.0594 0.8861 0.0 0
M  V30 17 C 1.0777 -6.5502 0.0 0
M  V30 18 C -6.6819 -2.0956 0.0 0
M  V30 19 C -5.3887 0.1676 0.0 0
M  V30 20 C 1.0418 -8.0112 0.0 0
M  V30 21 C -6.8735 -3.5445 0.0 0
M  V30 22 C -8.083 -1.4369 0.0 0
M  V30 23 N -8.3704 -3.8199 0.0 0
M  V30 24 C -9.1128 -2.5027 0.0 0
M  V30 25 N -10.6456 -2.4668 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 2 8 13
M  V30 13 1 8 14
M  V30 14 1 9 15
M  V30 15 2 10 16
M  V30 16 2 11 17
M  V30 17 1 15 18
M  V30 18 2 15 19
M  V30 19 1 17 20
M  V30 20 2 18 21
M  V30 21 1 18 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 1 24 25
M  V30 25 1 13 17
M  V30 26 1 16 19
M  V30 27 2 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00139001.cdx

>  <name>
US20220000118A1-20220106-C00116

>  <Row No>
261

$$$$
US20220000118A1-20220106-C00117
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -1.3089 0.7665 0.0 0
M  V30 3 C -2.6179 0.0471 0.0 0
M  V30 4 C -1.3443 2.276 0.0 0
M  V30 5 C -3.9269 0.8137 0.0 0
M  V30 6 C -2.6533 -1.3915 0.0 0
M  V30 7 C -2.6533 3.0425 0.0 0
M  V30 8 C -3.9623 2.3231 0.0 0
M  V30 9 N -2.6887 4.552 0.0 0
M  V30 10 C -3.9977 5.3185 0.0 0
M  V30 11 O -4.0331 6.828 0.0 0
M  V30 12 N -5.3067 4.5991 0.0 0
M  V30 13 C -6.6157 5.3657 0.0 0
M  V30 14 C -7.9247 4.6463 0.0 0
M  V30 15 C -6.6511 6.8751 0.0 0
M  V30 16 C -9.2337 5.4128 0.0 0
M  V30 17 C -7.9601 7.6417 0.0 0
M  V30 18 C -10.5427 4.6935 0.0 0
M  V30 19 C -9.2691 6.9223 0.0 0
M  V30 20 C -10.7314 3.2665 0.0 0
M  V30 21 C -11.9224 5.3421 0.0 0
M  V30 22 N -12.2055 2.9953 0.0 0
M  V30 23 C -12.9366 4.2925 0.0 0
M  V30 24 N -14.4461 4.3279 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 7 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00140001.cdx

>  <name>
US20220000118A1-20220106-C00117

>  <Row No>
262

$$$$
US20220000118A1-20220106-C00118
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -0.0354 1.5143 0.0 0
M  V30 3 C -1.3486 2.2832 0.0 0
M  V30 4 C 1.2067 2.2832 0.0 0
M  V30 5 F -2.6618 1.5734 0.0 0
M  V30 6 C -1.3841 3.7976 0.0 0
M  V30 7 F 2.4489 1.5734 0.0 0
M  V30 8 C 1.1712 3.7976 0.0 0
M  V30 9 C -0.1419 4.5665 0.0 0
M  V30 10 N -0.1774 6.0808 0.0 0
M  V30 11 C -1.4906 6.8498 0.0 0
M  V30 12 O -1.5261 8.3641 0.0 0
M  V30 13 N -2.8038 6.14 0.0 0
M  V30 14 C -4.117 6.909 0.0 0
M  V30 15 C -5.4302 6.1992 0.0 0
M  V30 16 C -4.1525 8.4233 0.0 0
M  V30 17 C -6.7434 6.9681 0.0 0
M  V30 18 C -5.4657 9.1923 0.0 0
M  V30 19 C -8.0566 6.2583 0.0 0
M  V30 20 C -6.7789 8.4824 0.0 0
M  V30 21 C -8.2458 4.8268 0.0 0
M  V30 22 C -9.4407 6.909 0.0 0
M  V30 23 N -9.7247 4.5547 0.0 0
M  V30 24 C -10.4582 5.8561 0.0 0
M  V30 25 N -11.9725 5.8916 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 6 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 2 11 12
M  V30 12 1 11 13
M  V30 13 1 13 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 2 19 21
M  V30 21 1 19 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 1 24 25
M  V30 25 1 8 9
M  V30 26 1 18 20
M  V30 27 2 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00141001.cdx

>  <name>
US20220000118A1-20220106-C00118

>  <Row No>
263

$$$$
US20220000118A1-20220106-C00119
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0355 1.5185 0.0 0
M  V30 3 C 1.2101 2.2778 0.0 0
M  V30 4 C -1.3524 2.2778 0.0 0
M  V30 5 N 2.4558 1.566 0.0 0 CHG=1
M  V30 6 C 1.1745 3.7964 0.0 0
M  V30 7 C -1.388 3.7964 0.0 0
M  V30 8 O 2.4202 0.1186 0.0 0
M  V30 9 O 3.7015 2.3253 0.0 0 CHG=-1
M  V30 10 C -0.1423 4.5675 0.0 0
M  V30 11 N -0.1779 6.0861 0.0 0
M  V30 12 C -1.4948 6.8573 0.0 0
M  V30 13 O -1.5304 8.3758 0.0 0
M  V30 14 N -2.8117 6.1454 0.0 0
M  V30 15 C -4.1286 6.9166 0.0 0
M  V30 16 C -5.4455 6.2047 0.0 0
M  V30 17 C -4.1642 8.4351 0.0 0
M  V30 18 C -6.7623 6.9759 0.0 0
M  V30 19 C -5.481 9.1944 0.0 0
M  V30 20 C -8.0792 6.2641 0.0 0
M  V30 21 C -6.7979 8.4945 0.0 0
M  V30 22 C -8.2691 4.8285 0.0 0
M  V30 23 C -9.4673 6.9166 0.0 0
M  V30 24 N -9.752 4.5557 0.0 0
M  V30 25 C -10.4876 5.8607 0.0 0
M  V30 26 N -12.0062 5.8963 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 2 20 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 25 26
M  V30 26 1 7 10
M  V30 27 1 19 21
M  V30 28 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00142001.cdx

>  <name>
US20220000118A1-20220106-C00119

>  <Row No>
264

$$$$
US20220000118A1-20220106-C00120
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0354 1.5136 0.0 0
M  V30 3 C 1.2061 2.2704 0.0 0
M  V30 4 C -1.348 2.2704 0.0 0
M  V30 5 C 1.1706 3.784 0.0 0
M  V30 6 C 2.4478 1.5609 0.0 0
M  V30 7 C -1.3835 3.784 0.0 0
M  V30 8 C -0.1419 4.5526 0.0 0
M  V30 9 N -0.1773 6.0663 0.0 0
M  V30 10 C -1.4899 6.8349 0.0 0
M  V30 11 O -1.5254 8.3485 0.0 0
M  V30 12 N -2.8025 6.1136 0.0 0
M  V30 13 C -4.1151 6.8822 0.0 0
M  V30 14 C -5.4277 6.1609 0.0 0
M  V30 15 C -4.1506 8.3958 0.0 0
M  V30 16 C -6.7403 6.9295 0.0 0
M  V30 17 C -5.4632 9.1644 0.0 0
M  V30 18 C -8.0529 6.2082 0.0 0
M  V30 19 C -6.7758 8.4431 0.0 0
M  V30 20 C -8.2421 4.7773 0.0 0
M  V30 21 C -9.4364 6.8585 0.0 0
M  V30 22 N -9.7202 4.5053 0.0 0
M  V30 23 C -10.4534 5.8061 0.0 0
M  V30 24 N -11.967 5.8416 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 7 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00143001.cdx

>  <name>
US20220000118A1-20220106-C00120

>  <Row No>
265

$$$$
US20220000118A1-20220106-C00121
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4621 0.0 0
M  V30 3 N -1.3662 -2.1932 0.0 0
M  V30 4 N 1.2224 -2.1932 0.0 0
M  V30 5 C -2.6965 -1.4142 0.0 0
M  V30 6 C 1.1864 -3.6553 0.0 0
M  V30 7 C -4.0268 -2.1452 0.0 0
M  V30 8 C -2.7325 0.1198 0.0 0
M  V30 9 C -0.1438 -4.3864 0.0 0
M  V30 10 C 2.4448 -4.3864 0.0 0
M  V30 11 C -5.3572 -1.3662 0.0 0
M  V30 12 C -4.0628 0.8988 0.0 0
M  V30 13 C -0.1797 -5.8485 0.0 0
M  V30 14 C 2.4089 -5.8485 0.0 0
M  V30 15 C -6.6875 -2.0973 0.0 0
M  V30 16 C -5.3931 0.1677 0.0 0
M  V30 17 C 1.0786 -6.5796 0.0 0
M  V30 18 C -6.8792 -3.5474 0.0 0
M  V30 19 C -8.0897 -1.4381 0.0 0
M  V30 20 C 1.0426 -8.0417 0.0 0
M  V30 21 N -8.3773 -3.8231 0.0 0
M  V30 22 C -9.1204 -2.5048 0.0 0
M  V30 23 O -0.2876 -8.7728 0.0 0
M  V30 24 O 2.301 -8.7728 0.0 0
M  V30 25 N -10.6424 -2.313 0.0 0
M  V30 26 C 3.5594 -7.9938 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 2 20 23
M  V30 23 1 20 24
M  V30 24 1 22 25
M  V30 25 1 24 26
M  V30 26 1 12 16
M  V30 27 1 14 17
M  V30 28 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00144001.cdx

>  <name>
US20220000118A1-20220106-C00121

>  <Row No>
266

$$$$
US20220000118A1-20220106-C00122
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4634 0.0 0
M  V30 3 N 1.2235 -2.1951 0.0 0
M  V30 4 N -1.3674 -2.1951 0.0 0
M  V30 5 C 1.1875 -3.6586 0.0 0
M  V30 6 C -2.6989 -1.4034 0.0 0
M  V30 7 C 2.447 -4.3783 0.0 0
M  V30 8 C -0.1439 -4.3783 0.0 0
M  V30 9 C -4.0304 -2.1351 0.0 0
M  V30 10 C -2.7349 0.1319 0.0 0
M  V30 11 C 2.411 -5.8417 0.0 0
M  V30 12 C -0.1799 -5.8417 0.0 0
M  V30 13 C -5.3619 -1.3554 0.0 0
M  V30 14 C -4.0664 0.9116 0.0 0
M  V30 15 C 3.6705 -6.5614 0.0 0
M  V30 16 C 1.0795 -6.5614 0.0 0
M  V30 17 C -6.6934 -2.0872 0.0 0
M  V30 18 C -5.3979 0.1799 0.0 0
M  V30 19 N 4.9301 -7.2812 0.0 0
M  V30 20 C -6.8853 -3.5386 0.0 0
M  V30 21 C -8.0969 -1.4274 0.0 0
M  V30 22 N -8.3847 -3.8145 0.0 0
M  V30 23 C -9.1285 -2.495 0.0 0
M  V30 24 N -10.6519 -2.3031 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 3 15 19
M  V30 19 2 17 20
M  V30 20 1 17 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 12 16
M  V30 25 1 14 18
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00145001.cdx

>  <name>
US20220000118A1-20220106-C00122

>  <Row No>
267

$$$$
US20220000118A1-20220106-C00123
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.462 0.0 0
M  V30 3 N -1.3661 -2.193 0.0 0
M  V30 4 N 1.2223 -2.193 0.0 0
M  V30 5 C -2.6963 -1.402 0.0 0
M  V30 6 C 1.1863 -3.655 0.0 0
M  V30 7 C -4.0264 -2.133 0.0 0
M  V30 8 C -2.7322 0.1318 0.0 0
M  V30 9 C -0.1438 -4.374 0.0 0
M  V30 10 C 2.4446 -4.374 0.0 0
M  V30 11 C -5.3566 -1.3541 0.0 0
M  V30 12 C -4.0624 0.9227 0.0 0
M  V30 13 C -0.1797 -5.836 0.0 0
M  V30 14 C 2.4087 -5.836 0.0 0
M  V30 15 C -6.6868 -2.0851 0.0 0
M  V30 16 C -5.3926 0.1797 0.0 0
M  V30 17 C 1.0785 -6.555 0.0 0
M  V30 18 C -6.8785 -3.5351 0.0 0
M  V30 19 C -8.0889 -1.426 0.0 0
M  V30 20 C 1.0425 -8.017 0.0 0
M  V30 21 N -8.3765 -3.8107 0.0 0
M  V30 22 C -9.1195 -2.4925 0.0 0
M  V30 23 N 1.0066 -9.479 0.0 0
M  V30 24 N -10.6414 -2.3008 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 3 20 23
M  V30 23 1 22 24
M  V30 24 1 12 16
M  V30 25 1 14 17
M  V30 26 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00146001.cdx

>  <name>
US20220000118A1-20220106-C00123

>  <Row No>
268

$$$$
US20220000118A1-20220106-C00124
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4665 0.0 0
M  V30 3 N 1.2261 -2.1878 0.0 0
M  V30 4 N -1.3704 -2.1878 0.0 0
M  V30 5 C 1.19 -3.6544 0.0 0
M  V30 6 C -2.7047 -1.4184 0.0 0
M  V30 7 C 2.4523 -4.3756 0.0 0
M  V30 8 C -0.1442 -4.3756 0.0 0
M  V30 9 C -4.039 -2.1397 0.0 0
M  V30 10 C -2.7408 0.1202 0.0 0
M  V30 11 C 2.4162 -5.8422 0.0 0
M  V30 12 C -0.1803 -5.8422 0.0 0
M  V30 13 C -5.3734 -1.3704 0.0 0
M  V30 14 C -4.0751 0.9015 0.0 0
M  V30 15 O 3.6784 -6.5635 0.0 0
M  V30 16 C 1.0819 -6.5635 0.0 0
M  V30 17 C -6.7077 -2.0916 0.0 0
M  V30 18 C -5.4095 0.1682 0.0 0
M  V30 19 C 4.9406 -5.7821 0.0 0
M  V30 20 O 1.0458 -8.0301 0.0 0
M  V30 21 C -6.9001 -3.5462 0.0 0
M  V30 22 C -8.1142 -1.4305 0.0 0
M  V30 23 C 2.308 -8.7633 0.0 0
M  V30 24 N -8.4027 -3.8227 0.0 0
M  V30 25 C -9.148 -2.5003 0.0 0
M  V30 26 N -10.6867 -2.4643 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 1 15 19
M  V30 19 1 16 20
M  V30 20 2 17 21
M  V30 21 1 17 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 25 26
M  V30 26 1 12 16
M  V30 27 1 14 18
M  V30 28 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00147001.cdx

>  <name>
US20220000118A1-20220106-C00124

>  <Row No>
269

$$$$
US20220000118A1-20220106-C00125
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4647 0.0 0
M  V30 3 N -1.3687 -2.1971 0.0 0
M  V30 4 N 1.2246 -2.1971 0.0 0
M  V30 5 C -2.7014 -1.4167 0.0 0
M  V30 6 C 1.1886 -3.6619 0.0 0
M  V30 7 C -4.0341 -2.1491 0.0 0
M  V30 8 C -2.7374 0.12 0.0 0
M  V30 9 C 2.4493 -4.3943 0.0 0
M  V30 10 C -0.144 -4.3943 0.0 0
M  V30 11 C -5.3669 -1.3687 0.0 0
M  V30 12 C -4.0702 0.9004 0.0 0
M  V30 13 C 2.4133 -5.8591 0.0 0
M  V30 14 C -0.18 -5.8591 0.0 0
M  V30 15 C -6.6996 -2.1011 0.0 0
M  V30 16 C -5.4029 0.168 0.0 0
M  V30 17 O 3.4818 -6.8197 0.0 0
M  V30 18 C 1.0805 -6.5915 0.0 0
M  V30 19 C -6.8917 -3.5539 0.0 0
M  V30 20 C -8.1043 -1.4407 0.0 0
M  V30 21 C 2.8215 -8.1524 0.0 0
M  V30 22 O 1.3567 -8.0203 0.0 0
M  V30 23 N -8.3925 -3.83 0.0 0
M  V30 24 C -9.1369 -2.5093 0.0 0
M  V30 25 N -10.6737 -2.4733 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 24 25
M  V30 25 1 12 16
M  V30 26 1 14 18
M  V30 27 1 21 22
M  V30 28 2 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00148001.cdx

>  <name>
US20220000118A1-20220106-C00125

>  <Row No>
270

$$$$
US20220000118A1-20220106-C00126
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4661 0.0 0
M  V30 3 N 1.2258 -2.1872 0.0 0
M  V30 4 N -1.37 -2.1872 0.0 0
M  V30 5 C 1.1897 -3.6534 0.0 0
M  V30 6 C -2.704 -1.4061 0.0 0
M  V30 7 C 2.4516 -4.3865 0.0 0
M  V30 8 C -0.1442 -4.3865 0.0 0
M  V30 9 C -4.038 -2.1271 0.0 0
M  V30 10 C -2.74 0.1321 0.0 0
M  V30 11 C 2.4156 -5.8527 0.0 0
M  V30 12 C -0.1802 -5.8527 0.0 0
M  V30 13 C -5.372 -1.346 0.0 0
M  V30 14 C -4.074 0.9133 0.0 0
M  V30 15 O 3.6774 -6.5738 0.0 0
M  V30 16 C 1.0816 -6.5738 0.0 0
M  V30 17 C -6.706 -2.067 0.0 0
M  V30 18 C -5.408 0.1922 0.0 0
M  V30 19 C 3.6414 -8.04 0.0 0
M  V30 20 O 1.0455 -8.04 0.0 0
M  V30 21 C -6.8983 -3.5212 0.0 0
M  V30 22 C -8.1121 -1.4061 0.0 0
M  V30 23 C 2.3074 -8.761 0.0 0
M  V30 24 N -8.4005 -3.7976 0.0 0
M  V30 25 C -9.1456 -2.4756 0.0 0
M  V30 26 N -10.6839 -2.4396 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 1 15 19
M  V30 19 1 16 20
M  V30 20 2 17 21
M  V30 21 1 17 22
M  V30 22 1 19 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 25 26
M  V30 26 1 12 16
M  V30 27 1 14 18
M  V30 28 1 20 23
M  V30 29 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00149001.cdx

>  <name>
US20220000118A1-20220106-C00126

>  <Row No>
271

$$$$
US20220000118A1-20220106-C00127
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 C -0.3435 1.4807 0.0 0
M  V30 3 C 1.4333 -0.1184 0.0 0
M  V30 4 C 0.9003 2.2389 0.0 0
M  V30 5 C -1.6584 2.2389 0.0 0
M  V30 6 C 2.0138 1.2675 0.0 0
M  V30 7 C 0.8647 3.7552 0.0 0
M  V30 8 C -1.694 3.7552 0.0 0
M  V30 9 C -0.4501 4.5134 0.0 0
M  V30 10 N -0.4856 6.0297 0.0 0
M  V30 11 C -1.8006 6.7879 0.0 0
M  V30 12 O -1.8361 8.3042 0.0 0
M  V30 13 N -3.1155 6.0771 0.0 0
M  V30 14 C -4.4305 6.8352 0.0 0
M  V30 15 C -5.7454 6.1245 0.0 0
M  V30 16 C -4.466 8.3516 0.0 0
M  V30 17 C -7.0603 6.8826 0.0 0
M  V30 18 C -5.7809 9.1097 0.0 0
M  V30 19 C -8.3753 6.1719 0.0 0
M  V30 20 C -7.0959 8.399 0.0 0
M  V30 21 C -8.5648 4.7385 0.0 0
M  V30 22 C -9.7613 6.8234 0.0 0
M  V30 23 N -10.0456 4.466 0.0 0
M  V30 24 C -10.7801 5.7691 0.0 0
M  V30 25 N -12.2845 5.9586 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 2 3 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 2 7 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 2 11 12
M  V30 12 1 11 13
M  V30 13 1 13 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 2 19 21
M  V30 21 1 19 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 1 24 25
M  V30 25 1 4 6
M  V30 26 1 8 9
M  V30 27 1 18 20
M  V30 28 2 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00150001.cdx

>  <name>
US20220000118A1-20220106-C00127

>  <Row No>
272

$$$$
US20220000118A1-20220106-C00128
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0354 1.5127 0.0 0
M  V30 3 C -1.3472 2.269 0.0 0
M  V30 4 C 1.2054 2.269 0.0 0
M  V30 5 N -1.3827 3.7817 0.0 0
M  V30 6 C 1.1699 3.7817 0.0 0
M  V30 7 C -0.1418 4.5381 0.0 0
M  V30 8 N -0.1772 6.0508 0.0 0
M  V30 9 C -1.489 6.8071 0.0 0
M  V30 10 O -1.5245 8.3198 0.0 0
M  V30 11 N -2.8008 6.0981 0.0 0
M  V30 12 C -4.1126 6.8544 0.0 0
M  V30 13 C -5.4244 6.1453 0.0 0
M  V30 14 C -4.1481 8.3671 0.0 0
M  V30 15 C -6.7362 6.9017 0.0 0
M  V30 16 C -5.4599 9.1353 0.0 0
M  V30 17 C -8.048 6.1926 0.0 0
M  V30 18 C -6.7717 8.4144 0.0 0
M  V30 19 C -8.2371 4.7626 0.0 0
M  V30 20 C -9.4307 6.8426 0.0 0
M  V30 21 N -9.7144 4.4908 0.0 0
M  V30 22 C -10.4471 5.7908 0.0 0
M  V30 23 N -11.948 5.9799 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 1 15 17
M  V30 17 2 15 18
M  V30 18 2 17 19
M  V30 19 1 17 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 22 23
M  V30 23 1 6 7
M  V30 24 1 16 18
M  V30 25 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00151001.cdx

>  <name>
US20220000118A1-20220106-C00128

>  <Row No>
273

$$$$
US20220000118A1-20220106-C00129
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 1.4459 0.0355 0.0 0
M  V30 3 F 1.4103 -1.4103 0.0 0
M  V30 4 F 2.8918 0.0711 0.0 0
M  V30 5 C 1.4103 1.5526 0.0 0
M  V30 6 N 0.0948 2.3229 0.0 0
M  V30 7 C 2.6548 2.3229 0.0 0
M  V30 8 C 0.0592 3.84 0.0 0
M  V30 9 C 2.6192 3.84 0.0 0
M  V30 10 C 1.3037 4.6104 0.0 0
M  V30 11 N 1.2681 6.1274 0.0 0
M  V30 12 C -0.0474 6.8978 0.0 0
M  V30 13 O -0.0829 8.4149 0.0 0
M  V30 14 N -1.3629 6.1748 0.0 0
M  V30 15 C -2.6785 6.9334 0.0 0
M  V30 16 C -3.9941 6.2104 0.0 0
M  V30 17 C -2.7141 8.4504 0.0 0
M  V30 18 C -5.3096 6.9689 0.0 0
M  V30 19 C -4.0296 9.2208 0.0 0
M  V30 20 C -6.6252 6.246 0.0 0
M  V30 21 C -5.3452 8.486 0.0 0
M  V30 22 C -6.8149 4.8119 0.0 0
M  V30 23 C -8.0119 6.8978 0.0 0
M  V30 24 N -8.2964 4.5393 0.0 0
M  V30 25 C -9.0312 5.843 0.0 0
M  V30 26 N -10.5364 6.0326 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 2 8 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 2 20 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 25 26
M  V30 26 1 9 10
M  V30 27 1 19 21
M  V30 28 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00152001.cdx

>  <name>
US20220000118A1-20220106-C00129

>  <Row No>
274

$$$$
US20220000118A1-20220106-C00130
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0354 1.5136 0.0 0
M  V30 3 N -1.348 2.2822 0.0 0
M  V30 4 C 1.2061 2.2822 0.0 0
M  V30 5 C -1.3835 3.7959 0.0 0
M  V30 6 Cl 2.4478 1.5727 0.0 0
M  V30 7 C 1.1707 3.7959 0.0 0
M  V30 8 C -0.1419 4.5527 0.0 0
M  V30 9 N -0.1773 6.0663 0.0 0
M  V30 10 C -1.4899 6.835 0.0 0
M  V30 11 O -1.5254 8.3486 0.0 0
M  V30 12 N -2.8025 6.1136 0.0 0
M  V30 13 C -4.1151 6.8823 0.0 0
M  V30 14 C -5.4278 6.1609 0.0 0
M  V30 15 C -4.1506 8.3959 0.0 0
M  V30 16 C -6.7404 6.9296 0.0 0
M  V30 17 C -5.4632 9.1645 0.0 0
M  V30 18 C -8.053 6.2082 0.0 0
M  V30 19 C -6.7758 8.4432 0.0 0
M  V30 20 C -8.2422 4.7774 0.0 0
M  V30 21 C -9.4365 6.8586 0.0 0
M  V30 22 N -9.7203 4.5054 0.0 0
M  V30 23 C -10.4535 5.8062 0.0 0
M  V30 24 N -11.9553 5.9954 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 7 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00153001.cdx

>  <name>
US20220000118A1-20220106-C00130

>  <Row No>
275

$$$$
US20220000118A1-20220106-C00131
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -0.4967 1.4429 0.0 0
M  V30 3 F 0.8752 1.9397 0.0 0
M  V30 4 F -0.9935 2.8859 0.0 0
M  V30 5 C -1.9397 1.0171 0.0 0
M  V30 6 O -2.4365 -0.3548 0.0 0
M  V30 7 C -3.1698 1.916 0.0 0
M  V30 8 C -3.9504 -0.3193 0.0 0
M  V30 9 N -3.2053 3.43 0.0 0
M  V30 10 C -4.3999 1.0881 0.0 0
M  V30 11 C -4.8493 -1.4784 0.0 0
M  V30 12 C -4.5182 4.1988 0.0 0
M  V30 13 O -4.5536 5.7128 0.0 0
M  V30 14 N -5.831 3.4891 0.0 0
M  V30 15 C -7.1439 4.2579 0.0 0
M  V30 16 C -8.4568 3.5483 0.0 0
M  V30 17 C -7.1794 5.7719 0.0 0
M  V30 18 C -9.7697 4.3053 0.0 0
M  V30 19 C -8.4923 6.5407 0.0 0
M  V30 20 C -11.0826 3.5956 0.0 0
M  V30 21 C -9.8052 5.8192 0.0 0
M  V30 22 C -11.2718 2.1644 0.0 0
M  V30 23 C -12.4664 4.2461 0.0 0
M  V30 24 N -12.7503 1.8924 0.0 0
M  V30 25 C -13.4836 3.1934 0.0 0
M  V30 26 N -14.9857 3.3827 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 5 6
M  V30 6 2 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 2 20 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 25 26
M  V30 26 2 8 10
M  V30 27 1 19 21
M  V30 28 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00154001.cdx

>  <name>
US20220000118A1-20220106-C00131

>  <Row No>
276

$$$$
US20220000118A1-20220106-C00132
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.2486 0.7729 0.0 0
M  V30 3 N 2.4972 0.0475 0.0 0
M  V30 4 C 1.2129 2.2951 0.0 0
M  V30 5 C 3.7459 0.8205 0.0 0
M  V30 6 C 2.4616 3.0561 0.0 0
M  V30 7 Cl 4.9945 0.0951 0.0 0
M  V30 8 C 3.7102 2.3426 0.0 0
M  V30 9 N 2.4259 4.5783 0.0 0
M  V30 10 C 1.1059 5.3513 0.0 0
M  V30 11 O 1.0702 6.8734 0.0 0
M  V30 12 N -0.214 4.6259 0.0 0
M  V30 13 C -1.534 5.3988 0.0 0
M  V30 14 C -2.854 4.6734 0.0 0
M  V30 15 C -1.5697 6.921 0.0 0
M  V30 16 C -4.174 5.4345 0.0 0
M  V30 17 C -2.8897 7.694 0.0 0
M  V30 18 C -5.494 4.7091 0.0 0
M  V30 19 C -4.2097 6.9567 0.0 0
M  V30 20 C -5.6842 3.2702 0.0 0
M  V30 21 C -6.8853 5.3632 0.0 0
M  V30 22 N -7.1707 2.9967 0.0 0
M  V30 23 C -7.908 4.3048 0.0 0
M  V30 24 N -9.4183 4.4951 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 6 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00155001.cdx

>  <name>
US20220000118A1-20220106-C00132

>  <Row No>
277

$$$$
US20220000118A1-20220106-C00133
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3135 0.7692 0.0 0
M  V30 3 C -2.6271 0.0473 0.0 0
M  V30 4 C -1.349 2.2839 0.0 0
M  V30 5 Cl -2.6626 -1.3964 0.0 0
M  V30 6 C -3.9407 0.8165 0.0 0
M  V30 7 C -2.6626 3.0413 0.0 0
M  V30 8 C -3.9762 2.3312 0.0 0
M  V30 9 N -2.6981 4.556 0.0 0
M  V30 10 C -4.0117 5.3252 0.0 0
M  V30 11 O -4.0472 6.84 0.0 0
M  V30 12 N -5.3252 4.6152 0.0 0
M  V30 13 C -6.6388 5.3726 0.0 0
M  V30 14 C -7.9524 4.6625 0.0 0
M  V30 15 C -6.6743 6.8873 0.0 0
M  V30 16 C -9.266 5.4199 0.0 0
M  V30 17 C -7.9879 7.6447 0.0 0
M  V30 18 C -10.5795 4.7099 0.0 0
M  V30 19 C -9.3015 6.9347 0.0 0
M  V30 20 C -10.7689 3.278 0.0 0
M  V30 21 C -11.9641 5.3607 0.0 0
M  V30 22 N -12.2481 3.0058 0.0 0
M  V30 23 C -9.7157 2.3312 0.0 0
M  V30 24 C -12.9818 4.3075 0.0 0
M  V30 25 N -14.4848 4.4969 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 24 25
M  V30 25 1 7 8
M  V30 26 1 17 19
M  V30 27 2 22 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00156001.cdx

>  <name>
US20220000118A1-20220106-C00133

>  <Row No>
278

$$$$
US20220000118A1-20220106-C00134
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0355 1.5158 0.0 0
M  V30 3 C -1.35 2.2737 0.0 0
M  V30 4 C 1.2079 2.2737 0.0 0
M  V30 5 C -1.3855 3.7895 0.0 0
M  V30 6 C 1.1723 3.7895 0.0 0
M  V30 7 C -0.1421 4.5474 0.0 0
M  V30 8 N -0.1776 6.0632 0.0 0
M  V30 9 C -1.4921 6.8211 0.0 0
M  V30 10 O -1.5276 8.3369 0.0 0
M  V30 11 N -2.8066 6.1106 0.0 0
M  V30 12 C -4.1211 6.8803 0.0 0
M  V30 13 C -5.4355 6.1698 0.0 0
M  V30 14 C -4.1566 8.3961 0.0 0
M  V30 15 C -6.75 6.9277 0.0 0
M  V30 16 C -5.4711 9.1659 0.0 0
M  V30 17 C -8.0645 6.2171 0.0 0
M  V30 18 C -6.7856 8.4435 0.0 0
M  V30 19 C -8.254 4.7842 0.0 0
M  V30 20 C -9.4501 6.8685 0.0 0
M  V30 21 N -9.7343 4.5118 0.0 0
M  V30 22 C -7.2 3.8368 0.0 0
M  V30 23 C -10.4685 5.8145 0.0 0
M  V30 24 N -11.9725 6.004 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 1 15 17
M  V30 17 2 15 18
M  V30 18 2 17 19
M  V30 19 1 17 20
M  V30 20 1 19 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 23 24
M  V30 24 1 6 7
M  V30 25 1 16 18
M  V30 26 2 21 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00157001.cdx

>  <name>
US20220000118A1-20220106-C00134

>  <Row No>
279

$$$$
US20220000118A1-20220106-C00135
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3209 -0.714 0.0 0
M  V30 3 C -2.6418 0.0476 0.0 0
M  V30 4 C -1.3566 -2.1658 0.0 0
M  V30 5 N -2.6775 1.5708 0.0 0
M  V30 6 C -3.9627 -0.6664 0.0 0
M  V30 7 C -2.6775 -2.8798 0.0 0
M  V30 8 C -3.9984 2.3324 0.0 0
M  V30 9 C -3.9984 -2.1182 0.0 0
M  V30 10 C -2.7132 -4.3316 0.0 0
M  V30 11 O -4.0341 3.8556 0.0 0
M  V30 12 N -5.3194 1.6065 0.0 0
M  V30 13 F -4.2364 -4.2959 0.0 0
M  V30 14 F -2.7489 -5.7835 0.0 0
M  V30 15 F -1.2614 -4.2959 0.0 0
M  V30 16 C -6.6403 2.3681 0.0 0
M  V30 17 C -7.9612 1.6422 0.0 0
M  V30 18 C -6.676 3.8913 0.0 0
M  V30 19 C -9.2821 2.4157 0.0 0
M  V30 20 C -7.9969 4.6648 0.0 0
M  V30 21 C -10.603 1.6898 0.0 0
M  V30 22 C -9.3178 3.9389 0.0 0
M  V30 23 C -10.7935 0.2499 0.0 0
M  V30 24 C -11.9954 2.3443 0.0 0
M  V30 25 N -12.281 -0.0238 0.0 0
M  V30 26 C -9.7343 -0.7021 0.0 0
M  V30 27 C -13.0188 1.2852 0.0 0
M  V30 28 N -14.5301 1.4756 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 1 10 15
M  V30 15 1 12 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 27 28
M  V30 28 1 7 9
M  V30 29 1 20 22
M  V30 30 2 25 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00158001.cdx

>  <name>
US20220000118A1-20220106-C00135

>  <Row No>
280

$$$$
US20220000118A1-20220106-C00136
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3137 0.7574 0.0 0
M  V30 3 C -2.6275 0.0473 0.0 0
M  V30 4 C -1.3492 2.2724 0.0 0
M  V30 5 F -2.663 -1.3966 0.0 0
M  V30 6 C -3.9412 0.8166 0.0 0
M  V30 7 C -2.663 3.0299 0.0 0
M  V30 8 C -3.9767 2.3316 0.0 0
M  V30 9 N -2.6985 4.5448 0.0 0
M  V30 10 C -4.0122 5.3023 0.0 0
M  V30 11 O -4.0477 6.8173 0.0 0
M  V30 12 N -5.326 4.5922 0.0 0
M  V30 13 C -6.6397 5.3615 0.0 0
M  V30 14 C -7.9535 4.6513 0.0 0
M  V30 15 C -6.6752 6.8764 0.0 0
M  V30 16 C -9.2672 5.4088 0.0 0
M  V30 17 C -7.989 7.6458 0.0 0
M  V30 18 C -10.581 4.6987 0.0 0
M  V30 19 C -9.3027 6.9238 0.0 0
M  V30 20 C -10.7704 3.2666 0.0 0
M  V30 21 C -11.9658 5.3497 0.0 0
M  V30 22 N -12.2498 2.9944 0.0 0
M  V30 23 C -9.717 2.3197 0.0 0
M  V30 24 C -12.9836 4.2963 0.0 0
M  V30 25 N -14.4867 4.4857 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 24 25
M  V30 25 1 7 8
M  V30 26 1 17 19
M  V30 27 2 22 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00159001.cdx

>  <name>
US20220000118A1-20220106-C00136

>  <Row No>
281

$$$$
US20220000118A1-20220106-C00137
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.2519 0.763 0.0 0
M  V30 3 C 2.5038 0.0476 0.0 0
M  V30 4 C 1.2161 2.2892 0.0 0
M  V30 5 C 3.7558 0.8227 0.0 0
M  V30 6 C 2.4681 3.0523 0.0 0
M  V30 7 Cl 5.0077 0.1073 0.0 0
M  V30 8 C 3.72 2.3488 0.0 0
M  V30 9 N 2.4323 4.5785 0.0 0
M  V30 10 C 1.1088 5.3535 0.0 0
M  V30 11 O 1.073 6.8797 0.0 0
M  V30 12 N -0.2146 4.6262 0.0 0
M  V30 13 C -1.5381 5.3893 0.0 0
M  V30 14 C -2.8615 4.6619 0.0 0
M  V30 15 C -1.5738 6.9154 0.0 0
M  V30 16 C -4.185 5.425 0.0 0
M  V30 17 C -2.8973 7.6905 0.0 0
M  V30 18 C -5.5085 4.6977 0.0 0
M  V30 19 C -4.2208 6.9512 0.0 0
M  V30 20 C -5.6993 3.255 0.0 0
M  V30 21 C -6.9035 5.3535 0.0 0
M  V30 22 N -7.1897 2.9808 0.0 0
M  V30 23 C -4.6381 2.3011 0.0 0
M  V30 24 C -7.9289 4.2923 0.0 0
M  V30 25 N -9.4432 4.4831 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 24 25
M  V30 25 1 6 8
M  V30 26 1 17 19
M  V30 27 2 22 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00160001.cdx

>  <name>
US20220000118A1-20220106-C00137

>  <Row No>
282

$$$$
US20220000118A1-20220106-C00138
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4673 0.0 0
M  V30 3 N -1.371 -2.1889 0.0 0
M  V30 4 N 1.2267 -2.1889 0.0 0
M  V30 5 C -2.7061 -1.4071 0.0 0
M  V30 6 C 1.1906 -3.6562 0.0 0
M  V30 7 C -4.0411 -2.1287 0.0 0
M  V30 8 C -2.7421 0.1322 0.0 0
M  V30 9 C -0.1443 -4.3778 0.0 0
M  V30 10 C 2.4535 -4.3778 0.0 0
M  V30 11 C -5.3761 -1.347 0.0 0
M  V30 12 C -4.0771 0.902 0.0 0
M  V30 13 C -0.1804 -5.8451 0.0 0
M  V30 14 C 2.4174 -5.8451 0.0 0
M  V30 15 C -6.7111 -2.0686 0.0 0
M  V30 16 C -5.4122 0.1924 0.0 0
M  V30 17 C 1.0824 -6.5668 0.0 0
M  V30 18 C -6.9035 -3.5239 0.0 0
M  V30 19 C -8.1183 -1.4071 0.0 0
M  V30 20 C 1.0463 -8.0341 0.0 0
M  V30 21 N -8.4069 -3.8005 0.0 0
M  V30 22 C -5.8331 -4.4861 0.0 0
M  V30 23 C -9.1526 -2.4775 0.0 0
M  V30 24 C 2.3092 -8.7677 0.0 0
M  V30 25 N -10.68 -2.2851 0.0 0
M  V30 26 C 3.572 -7.986 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 12 16
M  V30 27 1 14 17
M  V30 28 2 21 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00161001.cdx

>  <name>
US20220000118A1-20220106-C00138

>  <Row No>
283

$$$$
US20220000118A1-20220106-C00139
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C 1.2519 0.763 0.0 0
M  V30 3 C 2.5038 0.0476 0.0 0
M  V30 4 C 1.2161 2.2892 0.0 0
M  V30 5 C 3.7558 0.8227 0.0 0
M  V30 6 C 2.4681 3.0523 0.0 0
M  V30 7 Br 5.0077 0.1073 0.0 0
M  V30 8 C 3.72 2.3488 0.0 0
M  V30 9 N 2.4323 4.5785 0.0 0
M  V30 10 C 1.1088 5.3535 0.0 0
M  V30 11 O 1.073 6.8797 0.0 0
M  V30 12 N -0.2146 4.6262 0.0 0
M  V30 13 C -1.5381 5.3893 0.0 0
M  V30 14 C -2.8615 4.6619 0.0 0
M  V30 15 C -1.5738 6.9154 0.0 0
M  V30 16 C -4.185 5.425 0.0 0
M  V30 17 C -2.8973 7.6905 0.0 0
M  V30 18 C -5.5085 4.6977 0.0 0
M  V30 19 C -4.2208 6.9512 0.0 0
M  V30 20 C -5.6993 3.255 0.0 0
M  V30 21 C -6.9035 5.3535 0.0 0
M  V30 22 N -7.1897 2.9808 0.0 0
M  V30 23 C -4.6381 2.3011 0.0 0
M  V30 24 C -7.9289 4.2923 0.0 0
M  V30 25 N -9.4432 4.4831 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 24 25
M  V30 25 1 6 8
M  V30 26 1 17 19
M  V30 27 2 22 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00162001.cdx

>  <name>
US20220000118A1-20220106-C00139

>  <Row No>
284

$$$$
US20220000118A1-20220106-C00140
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3158 0.7587 0.0 0
M  V30 3 C -2.6317 0.0474 0.0 0
M  V30 4 C -1.3514 2.2761 0.0 0
M  V30 5 C -3.9476 0.8061 0.0 0
M  V30 6 C -2.6673 -1.3988 0.0 0
M  V30 7 C -2.6673 3.0348 0.0 0
M  V30 8 C -3.9832 2.3235 0.0 0
M  V30 9 F -4.1847 -1.3633 0.0 0
M  V30 10 F -2.7029 -2.8451 0.0 0
M  V30 11 F -1.221 -1.3633 0.0 0
M  V30 12 N -2.7029 4.5522 0.0 0
M  V30 13 C -4.0188 5.3228 0.0 0
M  V30 14 O -4.0543 6.8402 0.0 0
M  V30 15 N -5.3347 4.5997 0.0 0
M  V30 16 C -6.6506 5.3584 0.0 0
M  V30 17 C -7.9665 4.6352 0.0 0
M  V30 18 C -6.6861 6.8758 0.0 0
M  V30 19 C -9.2824 5.4058 0.0 0
M  V30 20 C -8.002 7.6464 0.0 0
M  V30 21 C -10.5983 4.6826 0.0 0
M  V30 22 C -9.3179 6.9232 0.0 0
M  V30 23 C -10.7879 3.2482 0.0 0
M  V30 24 C -11.9853 5.3347 0.0 0
M  V30 25 N -12.2698 2.9755 0.0 0
M  V30 26 C -9.7328 2.2998 0.0 0
M  V30 27 C -13.0048 4.2796 0.0 0
M  V30 28 N -14.5104 4.4693 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 27 28
M  V30 28 1 7 8
M  V30 29 1 20 22
M  V30 30 2 25 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00163001.cdx

>  <name>
US20220000118A1-20220106-C00140

>  <Row No>
285

$$$$
US20220000118A1-20220106-C00141
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3127 0.7568 0.0 0
M  V30 3 C -2.6254 0.0354 0.0 0
M  V30 4 C -1.3481 2.2706 0.0 0
M  V30 5 Cl -2.6608 -1.4073 0.0 0
M  V30 6 C -3.9381 0.8041 0.0 0
M  V30 7 C -2.6608 3.0393 0.0 0
M  V30 8 C -3.9735 2.3179 0.0 0
M  V30 9 N -2.6963 4.553 0.0 0
M  V30 10 C -4.009 5.3217 0.0 0
M  V30 11 O -4.0445 6.8355 0.0 0
M  V30 12 N -5.3217 4.6122 0.0 0
M  V30 13 C -6.6344 5.369 0.0 0
M  V30 14 C -7.9471 4.6595 0.0 0
M  V30 15 C -6.6699 6.8828 0.0 0
M  V30 16 C -9.2598 5.4163 0.0 0
M  V30 17 C -7.9826 7.6396 0.0 0
M  V30 18 C -9.2953 6.9301 0.0 0
M  V30 19 C -10.5725 4.7068 0.0 0
M  V30 20 C -10.608 7.687 0.0 0
M  V30 21 N -10.9155 3.2994 0.0 0
M  V30 22 C -11.8852 5.4636 0.0 0
M  V30 23 C -11.9207 6.9774 0.0 0
M  V30 24 C -12.4174 3.1812 0.0 0
M  V30 25 N -13.0087 4.5175 0.0 0
M  V30 26 N -13.1861 1.9394 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 2 16 18
M  V30 18 1 16 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 1 20 23
M  V30 23 2 21 24
M  V30 24 1 22 25
M  V30 25 1 24 26
M  V30 26 1 7 8
M  V30 27 1 17 18
M  V30 28 1 22 23
M  V30 29 1 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00164001.cdx

>  <name>
US20220000118A1-20220106-C00141

>  <Row No>
286

$$$$
US20220000118A1-20220106-C00142
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 32 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3141 0.7577 0.0 0
M  V30 3 C -2.6283 0.0473 0.0 0
M  V30 4 C -1.3496 2.2731 0.0 0
M  V30 5 C -3.9424 0.8169 0.0 0
M  V30 6 C -2.6638 -1.397 0.0 0
M  V30 7 C -2.6638 3.0308 0.0 0
M  V30 8 C -3.978 2.3323 0.0 0
M  V30 9 F -4.1792 -1.3615 0.0 0
M  V30 10 F -2.6993 -2.8414 0.0 0
M  V30 11 F -1.2194 -1.3615 0.0 0
M  V30 12 N -2.6993 4.5463 0.0 0
M  V30 13 C -4.0135 5.3158 0.0 0
M  V30 14 O -4.049 6.8312 0.0 0
M  V30 15 N -5.3276 4.5936 0.0 0
M  V30 16 C -6.6418 5.3632 0.0 0
M  V30 17 C -7.956 4.641 0.0 0
M  V30 18 C -6.6773 6.8786 0.0 0
M  V30 19 C -9.2701 5.4105 0.0 0
M  V30 20 C -7.9915 7.6482 0.0 0
M  V30 21 C -9.3057 6.926 0.0 0
M  V30 22 C -10.5843 4.6883 0.0 0
M  V30 23 C -10.6198 7.6955 0.0 0
M  V30 24 N -10.9276 3.2794 0.0 0
M  V30 25 C -11.8985 5.4579 0.0 0
M  V30 26 C -11.934 6.9733 0.0 0
M  V30 27 C -12.4312 3.1611 0.0 0
M  V30 28 N -13.0232 4.5107 0.0 0
M  V30 29 N -13.2008 1.9179 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 2 19 21
M  V30 21 1 19 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 2 22 25
M  V30 25 1 23 26
M  V30 26 2 24 27
M  V30 27 1 25 28
M  V30 28 1 27 29
M  V30 29 1 7 8
M  V30 30 1 20 21
M  V30 31 1 25 26
M  V30 32 1 27 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00165001.cdx

>  <name>
US20220000118A1-20220106-C00142

>  <Row No>
287

$$$$
US20220000118A1-20220106-C00143
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C 1.2497 0.7736 0.0 0
M  V30 3 C 2.4994 0.0476 0.0 0
M  V30 4 C 1.214 2.2971 0.0 0
M  V30 5 C 3.7491 0.8212 0.0 0
M  V30 6 C 2.4637 3.0707 0.0 0
M  V30 7 Br 4.9988 0.0952 0.0 0
M  V30 8 C 3.7134 2.3447 0.0 0
M  V30 9 N 2.428 4.5942 0.0 0
M  V30 10 C 1.1068 5.3678 0.0 0
M  V30 11 O 1.0711 6.8913 0.0 0
M  V30 12 N -0.2142 4.6537 0.0 0
M  V30 13 C -1.5353 5.4273 0.0 0
M  V30 14 C -2.8565 4.7132 0.0 0
M  V30 15 C -1.571 6.9508 0.0 0
M  V30 16 C -4.1776 5.4868 0.0 0
M  V30 17 C -2.8922 7.7244 0.0 0
M  V30 18 C -4.2133 7.0103 0.0 0
M  V30 19 C -5.4987 4.7727 0.0 0
M  V30 20 C -5.5344 7.7839 0.0 0
M  V30 21 N -5.8439 3.3564 0.0 0
M  V30 22 C -6.8199 5.5344 0.0 0
M  V30 23 C -6.8556 7.0579 0.0 0
M  V30 24 C -7.3555 3.2373 0.0 0
M  V30 25 N -7.9506 4.5823 0.0 0
M  V30 26 N -8.1291 1.9876 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 2 16 18
M  V30 18 1 16 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 1 20 23
M  V30 23 2 21 24
M  V30 24 1 22 25
M  V30 25 1 24 26
M  V30 26 1 6 8
M  V30 27 1 17 18
M  V30 28 1 22 23
M  V30 29 1 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00166001.cdx

>  <name>
US20220000118A1-20220106-C00143

>  <Row No>
288

$$$$
US20220000118A1-20220106-C00144
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 33 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3214 0.7619 0.0 0
M  V30 3 C -2.6429 0.0476 0.0 0
M  V30 4 C -1.3572 2.2858 0.0 0
M  V30 5 Cl -2.6786 -1.4048 0.0 0
M  V30 6 C -3.9644 0.8214 0.0 0
M  V30 7 C -2.6786 3.0596 0.0 0
M  V30 8 C -4.0001 2.3453 0.0 0
M  V30 9 N -2.7144 4.5835 0.0 0
M  V30 10 C -4.0359 5.3573 0.0 0
M  V30 11 O -4.0716 6.8812 0.0 0
M  V30 12 N -5.3573 4.643 0.0 0
M  V30 13 C -6.6788 5.4169 0.0 0
M  V30 14 C -8.0003 4.7025 0.0 0
M  V30 15 C -6.7145 6.9407 0.0 0
M  V30 16 C -9.3218 5.4764 0.0 0
M  V30 17 C -8.036 7.7146 0.0 0
M  V30 18 C -10.6433 4.7621 0.0 0
M  V30 19 C -9.3575 7.0003 0.0 0
M  V30 20 C -10.8338 3.3215 0.0 0
M  V30 21 C -12.0362 5.4169 0.0 0
M  V30 22 N -12.322 3.0477 0.0 0
M  V30 23 C -9.8218 2.3096 0.0 0
M  V30 24 C -13.0601 4.3573 0.0 0
M  V30 25 C -10.2504 0.9048 0.0 0
M  V30 26 C -8.417 2.7382 0.0 0
M  V30 27 N -14.5721 4.5478 0.0 0
M  V30 28 C -9.2385 -0.1071 0.0 0
M  V30 29 C -7.4051 1.7262 0.0 0
M  V30 30 C -7.8336 0.3214 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 2 23 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 2 26 29
M  V30 29 2 28 30
M  V30 30 1 7 8
M  V30 31 1 17 19
M  V30 32 2 22 24
M  V30 33 1 29 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00167001.cdx

>  <name>
US20220000118A1-20220106-C00144

>  <Row No>
289

$$$$
US20220000118A1-20220106-C00145
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 33 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3219 0.7741 0.0 0
M  V30 3 C -2.6439 0.0476 0.0 0
M  V30 4 C -1.3576 2.2985 0.0 0
M  V30 5 C -3.9659 0.8217 0.0 0
M  V30 6 C -2.6796 -1.4053 0.0 0
M  V30 7 C -2.6796 3.0607 0.0 0
M  V30 8 C -4.0016 2.3461 0.0 0
M  V30 9 N -2.7153 4.5852 0.0 0
M  V30 10 C -4.0373 5.3474 0.0 0
M  V30 11 O -4.073 6.8718 0.0 0
M  V30 12 N -5.3593 4.6328 0.0 0
M  V30 13 C -6.6812 5.395 0.0 0
M  V30 14 C -8.0032 4.6804 0.0 0
M  V30 15 C -6.717 6.9194 0.0 0
M  V30 16 C -9.3252 5.4546 0.0 0
M  V30 17 C -8.0389 7.6817 0.0 0
M  V30 18 C -10.6471 4.74 0.0 0
M  V30 19 C -9.3609 6.979 0.0 0
M  V30 20 C -10.8377 3.2989 0.0 0
M  V30 21 C -12.0406 5.395 0.0 0
M  V30 22 N -12.3264 3.025 0.0 0
M  V30 23 C -9.8254 2.2866 0.0 0
M  V30 24 C -13.0648 4.3351 0.0 0
M  V30 25 C -10.2541 0.8813 0.0 0
M  V30 26 C -8.42 2.7153 0.0 0
M  V30 27 N -14.5773 4.5256 0.0 0
M  V30 28 C -9.2418 -0.131 0.0 0
M  V30 29 C -7.4077 1.703 0.0 0
M  V30 30 C -7.8365 0.2977 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 2 23 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 2 26 29
M  V30 29 2 28 30
M  V30 30 1 7 8
M  V30 31 1 17 19
M  V30 32 2 22 24
M  V30 33 1 29 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00168001.cdx

>  <name>
US20220000118A1-20220106-C00145

>  <Row No>
290

$$$$
US20220000118A1-20220106-C00146
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3123 0.7566 0.0 0
M  V30 3 C -2.6246 0.0472 0.0 0
M  V30 4 C -1.3478 2.2699 0.0 0
M  V30 5 Cl -2.6601 -1.395 0.0 0
M  V30 6 C -3.9369 0.8157 0.0 0
M  V30 7 C -2.6601 3.0384 0.0 0
M  V30 8 C -3.9724 2.329 0.0 0
M  V30 9 N -2.6956 4.5517 0.0 0
M  V30 10 C -4.0079 5.3084 0.0 0
M  V30 11 O -4.0434 6.8217 0.0 0
M  V30 12 N -5.3202 4.599 0.0 0
M  V30 13 C -6.6326 5.3675 0.0 0
M  V30 14 C -7.9449 4.6581 0.0 0
M  V30 15 C -6.668 6.8808 0.0 0
M  V30 16 C -9.2572 5.4266 0.0 0
M  V30 17 C -7.9804 3.2158 0.0 0
M  V30 18 C -7.9804 7.6493 0.0 0
M  V30 19 C -10.5695 4.7173 0.0 0
M  V30 20 C -9.2927 6.9399 0.0 0
M  V30 21 C -9.2927 2.5064 0.0 0
M  V30 22 C -10.605 3.2749 0.0 0
M  V30 23 C -12.0119 5.2138 0.0 0
M  V30 24 N -12.0474 2.8492 0.0 0
M  V30 25 C -12.9105 4.0552 0.0 0
M  V30 26 N -14.4238 4.0906 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 1 16 19
M  V30 19 2 16 20
M  V30 20 1 17 21
M  V30 21 2 19 22
M  V30 22 1 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 25 26
M  V30 26 1 7 8
M  V30 27 1 18 20
M  V30 28 1 21 22
M  V30 29 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00169001.cdx

>  <name>
US20220000118A1-20220106-C00146

>  <Row No>
291

$$$$
US20220000118A1-20220106-C00147
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 0.7106 1.3147 0.0 0
M  V30 3 F 1.9544 0.604 0.0 0
M  V30 4 F 1.4332 2.6295 0.0 0
M  V30 5 C -0.604 2.0847 0.0 0
M  V30 6 C -1.9188 1.374 0.0 0
M  V30 7 C -0.6396 3.6008 0.0 0
M  V30 8 C -3.2336 2.1439 0.0 0
M  V30 9 C -1.9544 -0.071 0.0 0
M  V30 10 C -1.9544 4.3707 0.0 0
M  V30 11 C -3.2692 3.66 0.0 0
M  V30 12 N -1.9899 5.8869 0.0 0
M  V30 13 C -3.3047 6.6568 0.0 0
M  V30 14 O -3.3402 8.173 0.0 0
M  V30 15 N -4.6195 5.9461 0.0 0
M  V30 16 C -5.9343 6.716 0.0 0
M  V30 17 C -7.2491 5.9935 0.0 0
M  V30 18 C -5.9698 8.2322 0.0 0
M  V30 19 C -8.5639 6.7634 0.0 0
M  V30 20 C -7.2846 9.0021 0.0 0
M  V30 21 C -9.8787 6.0409 0.0 0
M  V30 22 C -8.5994 8.2796 0.0 0
M  V30 23 C -10.0682 4.6076 0.0 0
M  V30 24 C -11.2645 6.6924 0.0 0
M  V30 25 N -11.5488 4.3352 0.0 0
M  V30 26 C -9.014 3.66 0.0 0
M  V30 27 C -12.2832 5.6382 0.0 0
M  V30 28 N -13.7875 5.8277 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 2 7 10
M  V30 10 2 8 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 27 28
M  V30 28 1 10 11
M  V30 29 1 20 22
M  V30 30 2 25 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00170001.cdx

>  <name>
US20220000118A1-20220106-C00147

>  <Row No>
292

$$$$
US20220000118A1-20220106-C00148
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 32 35 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3249 0.7639 0.0 0
M  V30 3 C -2.6499 0.0477 0.0 0
M  V30 4 C -1.3607 2.2918 0.0 0
M  V30 5 Cl -2.6857 -1.4085 0.0 0
M  V30 6 C -3.9749 0.8117 0.0 0
M  V30 7 C -2.6857 3.0558 0.0 0
M  V30 8 C -4.0107 2.3396 0.0 0
M  V30 9 N -2.7215 4.5837 0.0 0
M  V30 10 C -4.0465 5.3476 0.0 0
M  V30 11 O -4.0823 6.8755 0.0 0
M  V30 12 N -5.3715 4.6314 0.0 0
M  V30 13 C -6.6965 5.3954 0.0 0
M  V30 14 C -8.0215 4.6792 0.0 0
M  V30 15 C -6.7323 6.9233 0.0 0
M  V30 16 C -9.3465 5.4431 0.0 0
M  V30 17 C -8.0573 7.6872 0.0 0
M  V30 18 C -10.6714 4.7269 0.0 0
M  V30 19 C -9.3823 6.971 0.0 0
M  V30 20 N -12.0681 5.3834 0.0 0
M  V30 21 C -10.8624 3.2826 0.0 0
M  V30 22 C -13.0946 4.3211 0.0 0
M  V30 23 N -12.3545 3.008 0.0 0
M  V30 24 N -14.6106 4.5121 0.0 0
M  V30 25 C -13.0111 1.683 0.0 0
M  V30 26 C -12.1755 0.5132 0.0 0
M  V30 27 C -12.832 -0.8117 0.0 0
M  V30 28 C -10.7311 0.7042 0.0 0
M  V30 29 C -11.9964 -1.9815 0.0 0
M  V30 30 C -9.8956 -0.4655 0.0 0
M  V30 31 C -10.5521 -1.7905 0.0 0
M  V30 32 F -9.7165 -2.9603 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 2 20 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 25 26
M  V30 26 2 26 27
M  V30 27 1 26 28
M  V30 28 1 27 29
M  V30 29 2 28 30
M  V30 30 2 29 31
M  V30 31 1 31 32
M  V30 32 1 7 8
M  V30 33 1 17 19
M  V30 34 1 22 23
M  V30 35 1 30 31
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00171001.cdx

>  <name>
US20220000118A1-20220106-C00148

>  <Row No>
293

$$$$
US20220000118A1-20220106-C00149
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 33 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3162 0.7707 0.0 0
M  V30 3 C -2.6324 0.0474 0.0 0
M  V30 4 C -1.3518 2.2885 0.0 0
M  V30 5 Cl -2.668 -1.3992 0.0 0
M  V30 6 C -3.9487 0.8182 0.0 0
M  V30 7 C -2.668 3.0474 0.0 0
M  V30 8 C -3.9842 2.336 0.0 0
M  V30 9 N -2.7036 4.5653 0.0 0
M  V30 10 C -4.0198 5.336 0.0 0
M  V30 11 O -4.0554 6.8539 0.0 0
M  V30 12 N -5.336 4.6246 0.0 0
M  V30 13 C -6.6523 5.3835 0.0 0
M  V30 14 C -7.9685 4.672 0.0 0
M  V30 15 C -6.6878 6.9013 0.0 0
M  V30 16 C -9.2847 5.4428 0.0 0
M  V30 17 C -8.0041 7.6721 0.0 0
M  V30 18 C -10.601 4.7313 0.0 0
M  V30 19 C -9.3203 6.9606 0.0 0
M  V30 20 C -10.7907 3.2965 0.0 0
M  V30 21 C -11.9884 5.3835 0.0 0
M  V30 22 N -12.273 3.0237 0.0 0
M  V30 23 C -13.0082 4.3281 0.0 0
M  V30 24 C -14.5141 4.5178 0.0 0
M  V30 25 C -15.4153 3.3558 0.0 0
M  V30 26 C -16.9213 3.5455 0.0 0
M  V30 27 C -14.8343 2.0395 0.0 0
M  V30 28 C -17.8225 2.3834 0.0 0
M  V30 29 C -15.7355 0.8774 0.0 0
M  V30 30 C -17.2414 1.0672 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 2 25 26
M  V30 26 1 25 27
M  V30 27 1 26 28
M  V30 28 2 27 29
M  V30 29 2 28 30
M  V30 30 1 7 8
M  V30 31 1 17 19
M  V30 32 2 22 23
M  V30 33 1 29 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00172001.cdx

>  <name>
US20220000118A1-20220106-C00149

>  <Row No>
294

$$$$
US20220000118A1-20220106-C00150
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 32 35 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.31 0.7671 0.0 0
M  V30 3 C -2.62 0.0472 0.0 0
M  V30 4 C -1.3454 2.2777 0.0 0
M  V30 5 Cl -2.6554 -1.3926 0.0 0
M  V30 6 C -3.93 0.8143 0.0 0
M  V30 7 C -2.6554 3.0331 0.0 0
M  V30 8 C -3.9654 2.3249 0.0 0
M  V30 9 N -2.6908 4.5437 0.0 0
M  V30 10 C -4.0008 5.299 0.0 0
M  V30 11 O -4.0362 6.8097 0.0 0
M  V30 12 N -5.3108 4.5909 0.0 0
M  V30 13 C -6.6209 5.3462 0.0 0
M  V30 14 C -7.9309 4.6381 0.0 0
M  V30 15 C -6.6563 6.8569 0.0 0
M  V30 16 C -9.2409 5.3935 0.0 0
M  V30 17 C -7.9663 7.624 0.0 0
M  V30 18 C -10.5509 4.6853 0.0 0
M  V30 19 C -9.2763 6.9041 0.0 0
M  V30 20 C -10.7397 3.2573 0.0 0
M  V30 21 C -11.9317 5.3344 0.0 0
M  V30 22 N -12.215 2.9858 0.0 0
M  V30 23 C -12.9467 4.2841 0.0 0
M  V30 24 N -14.4456 4.4729 0.0 0
M  V30 25 C -15.0947 5.8537 0.0 0
M  V30 26 O -14.2685 7.0811 0.0 0
M  V30 27 C -16.5935 6.0426 0.0 0
M  V30 28 C -17.2426 7.4234 0.0 0
M  V30 29 C -17.4905 4.886 0.0 0
M  V30 30 C -18.7415 7.6122 0.0 0
M  V30 31 C -18.9893 5.0748 0.0 0
M  V30 32 C -19.6384 6.4556 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 2 25 26
M  V30 26 1 25 27
M  V30 27 2 27 28
M  V30 28 1 27 29
M  V30 29 1 28 30
M  V30 30 2 29 31
M  V30 31 2 30 32
M  V30 32 1 7 8
M  V30 33 1 17 19
M  V30 34 2 22 23
M  V30 35 1 31 32
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00173001.cdx

>  <name>
US20220000118A1-20220106-C00150

>  <Row No>
295

$$$$
US20220000118A1-20220106-C00151
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3104 0.7673 0.0 0
M  V30 3 C -2.6208 0.0472 0.0 0
M  V30 4 C -1.3458 2.2784 0.0 0
M  V30 5 Cl -2.6562 -1.393 0.0 0
M  V30 6 C -3.9312 0.8145 0.0 0
M  V30 7 C -2.6562 3.0458 0.0 0
M  V30 8 C -3.9666 2.3257 0.0 0
M  V30 9 N -2.6916 4.5569 0.0 0
M  V30 10 C -4.0021 5.3243 0.0 0
M  V30 11 O -4.0375 6.8354 0.0 0
M  V30 12 N -5.3125 4.6041 0.0 0
M  V30 13 C -6.6229 5.3715 0.0 0
M  V30 14 C -6.6583 6.8826 0.0 0
M  V30 15 C -7.9333 4.6514 0.0 0
M  V30 16 F -5.4187 7.65 0.0 0
M  V30 17 C -7.9687 7.65 0.0 0
M  V30 18 C -9.2438 5.4187 0.0 0
M  V30 19 C -9.2792 6.9298 0.0 0
M  V30 20 C -10.5542 4.6986 0.0 0
M  V30 21 C -10.7431 3.2701 0.0 0
M  V30 22 C -11.9354 5.3479 0.0 0
M  V30 23 N -12.2188 2.9986 0.0 0
M  V30 24 C -12.9507 4.2972 0.0 0
M  V30 25 N -14.45 4.4861 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 2 20 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 1 24 25
M  V30 25 1 7 8
M  V30 26 1 18 19
M  V30 27 2 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00174001.cdx

>  <name>
US20220000118A1-20220106-C00151

>  <Row No>
296

$$$$
US20220000118A1-20220106-C00152
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -1.3378 -0.7352 0.0 0
M  V30 3 C -1.374 -2.2056 0.0 0
M  V30 4 C -2.6757 0.0482 0.0 0
M  V30 5 N -0.1084 -2.9409 0.0 0
M  V30 6 C -2.7119 -2.9409 0.0 0
M  V30 7 C -4.0136 -0.6749 0.0 0
M  V30 8 C 1.157 -2.1574 0.0 0
M  V30 9 C -4.0497 -2.1574 0.0 0
M  V30 10 O 1.1209 -0.6146 0.0 0
M  V30 11 N 2.4226 -2.8926 0.0 0
M  V30 12 C -5.3876 -2.8926 0.0 0
M  V30 13 C 2.3864 -4.3631 0.0 0
M  V30 14 C -5.5804 -4.3511 0.0 0
M  V30 15 C -6.7978 -2.2297 0.0 0
M  V30 16 C 1.0486 -5.0863 0.0 0
M  V30 17 C 3.652 -5.0863 0.0 0
M  V30 18 N -7.0871 -4.6283 0.0 0
M  V30 19 C -7.8343 -3.3024 0.0 0
M  V30 20 C 1.0124 -6.5567 0.0 0
M  V30 21 C 3.6158 -6.5567 0.0 0
M  V30 22 N -9.3771 -3.2663 0.0 0
M  V30 23 C 2.278 -7.292 0.0 0
M  V30 24 C 2.2418 -8.7624 0.0 0
M  V30 25 C 3.5073 -9.4976 0.0 0
M  V30 26 C 4.7729 -8.7142 0.0 0
M  V30 27 C 6.0385 -9.4494 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 1 11 13
M  V30 13 2 12 14
M  V30 14 1 12 15
M  V30 15 2 13 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 1 15 19
M  V30 19 1 16 20
M  V30 20 2 17 21
M  V30 21 1 19 22
M  V30 22 2 20 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 26 1 26 27
M  V30 27 1 7 9
M  V30 28 2 18 19
M  V30 29 1 21 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00175001.cdx

>  <name>
US20220000118A1-20220106-C00152

>  <Row No>
297

$$$$
US20220000118A1-20220106-C00153
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3106 0.7674 0.0 0
M  V30 3 C -2.6212 0.0472 0.0 0
M  V30 4 C -1.346 2.2788 0.0 0
M  V30 5 Cl -2.6566 -1.3932 0.0 0
M  V30 6 C -3.9318 0.8147 0.0 0
M  V30 7 C -2.6566 3.0463 0.0 0
M  V30 8 C -3.9672 2.326 0.0 0
M  V30 9 N -2.692 4.5576 0.0 0
M  V30 10 C -4.0026 5.3251 0.0 0
M  V30 11 O -4.0381 6.8364 0.0 0
M  V30 12 N -5.3133 4.6048 0.0 0
M  V30 13 C -6.6239 5.3723 0.0 0
M  V30 14 C -6.6593 6.8836 0.0 0
M  V30 15 C -7.9345 4.6521 0.0 0
M  V30 16 O -5.4195 7.6393 0.0 0
M  V30 17 C -7.9699 7.6393 0.0 0
M  V30 18 C -9.2451 5.4195 0.0 0
M  V30 19 C -5.455 9.1507 0.0 0
M  V30 20 C -9.2805 6.9309 0.0 0
M  V30 21 C -10.5557 4.6993 0.0 0
M  V30 22 C -10.7447 3.2706 0.0 0
M  V30 23 C -11.9372 5.3487 0.0 0
M  V30 24 N -12.2206 2.999 0.0 0
M  V30 25 C -12.9526 4.2978 0.0 0
M  V30 26 N -14.4522 4.4868 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 1 16 19
M  V30 19 2 17 20
M  V30 20 1 18 21
M  V30 21 2 21 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 25 26
M  V30 26 1 7 8
M  V30 27 1 18 20
M  V30 28 2 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00176001.cdx

>  <name>
US20220000118A1-20220106-C00153

>  <Row No>
298

$$$$
US20220000118A1-20220106-C00154
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3119 0.7682 0.0 0
M  V30 3 C -2.6238 0.0472 0.0 0
M  V30 4 C -1.3473 2.2811 0.0 0
M  V30 5 C -3.9357 0.8155 0.0 0
M  V30 6 C -2.6593 -1.3946 0.0 0
M  V30 7 C -2.6593 3.0493 0.0 0
M  V30 8 C -3.9712 2.3283 0.0 0
M  V30 9 N -2.6947 4.5622 0.0 0
M  V30 10 C -4.0067 5.3304 0.0 0
M  V30 11 O -4.0421 6.8433 0.0 0
M  V30 12 N -5.3186 4.6213 0.0 0
M  V30 13 C -6.6305 5.3777 0.0 0
M  V30 14 C -6.666 6.8906 0.0 0
M  V30 15 C -7.9425 4.6685 0.0 0
M  V30 16 F -5.425 7.647 0.0 0
M  V30 17 C -7.9779 7.647 0.0 0
M  V30 18 C -9.2544 5.425 0.0 0
M  V30 19 C -9.2899 6.9378 0.0 0
M  V30 20 C -10.5663 4.7158 0.0 0
M  V30 21 C -10.7554 3.2857 0.0 0
M  V30 22 C -11.9492 5.3659 0.0 0
M  V30 23 N -12.2328 3.0138 0.0 0
M  V30 24 C -12.9656 4.314 0.0 0
M  V30 25 N -14.4667 4.5031 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 2 20 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 1 24 25
M  V30 25 1 7 8
M  V30 26 1 18 19
M  V30 27 2 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00177001.cdx

>  <name>
US20220000118A1-20220106-C00154

>  <Row No>
299

$$$$
US20220000118A1-20220106-C00155
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 33 36 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3285 0.766 0.0 0
M  V30 3 C -2.6571 0.0478 0.0 0
M  V30 4 C -1.3644 2.298 0.0 0
M  V30 5 Cl -2.693 -1.4123 0.0 0
M  V30 6 C -3.9857 0.8138 0.0 0
M  V30 7 C -2.693 3.064 0.0 0
M  V30 8 C -4.0216 2.3459 0.0 0
M  V30 9 N -2.7289 4.5961 0.0 0
M  V30 10 C -1.4721 5.3741 0.0 0
M  V30 11 O -0.2154 4.6559 0.0 0
M  V30 12 N -1.5081 6.9061 0.0 0
M  V30 13 C -2.8366 7.6721 0.0 0
M  V30 14 C -0.2513 7.6721 0.0 0
M  V30 15 C -4.1652 6.954 0.0 0
M  V30 16 C -2.8725 9.2042 0.0 0
M  V30 17 C 1.0054 6.954 0.0 0
M  V30 18 C -5.4938 7.72 0.0 0
M  V30 19 C -4.2011 9.9702 0.0 0
M  V30 20 C 0.9694 5.4938 0.0 0
M  V30 21 C 2.2621 7.72 0.0 0
M  V30 22 C -6.8223 7.0019 0.0 0
M  V30 23 C -5.5297 9.2521 0.0 0
M  V30 24 C 2.2262 4.7756 0.0 0
M  V30 25 C 3.5189 7.0019 0.0 0
M  V30 26 C -7.0138 5.5536 0.0 0
M  V30 27 C -8.2227 7.6602 0.0 0
M  V30 28 F 2.1903 3.3154 0.0 0
M  V30 29 C 3.483 5.5416 0.0 0
M  V30 30 F 4.7756 7.7679 0.0 0
M  V30 31 N -8.51 5.2783 0.0 0
M  V30 32 C -9.2521 6.5949 0.0 0
M  V30 33 N -10.7841 6.6308 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 17 20
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 2 18 23
M  V30 23 1 20 24
M  V30 24 2 21 25
M  V30 25 2 22 26
M  V30 26 1 22 27
M  V30 27 1 24 28
M  V30 28 2 24 29
M  V30 29 1 25 30
M  V30 30 1 26 31
M  V30 31 1 27 32
M  V30 32 1 32 33
M  V30 33 1 7 8
M  V30 34 1 19 23
M  V30 35 1 25 29
M  V30 36 2 31 32
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00178001.cdx

>  <name>
US20220000118A1-20220106-C00155

>  <Row No>
300

$$$$
US20220000118A1-20220106-C00156
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3125 0.7685 0.0 0
M  V30 3 C -2.625 0.0472 0.0 0
M  V30 4 C -1.3479 2.282 0.0 0
M  V30 5 Cl -2.6604 -1.3952 0.0 0
M  V30 6 C -3.9375 0.8158 0.0 0
M  V30 7 C -2.6604 3.0388 0.0 0
M  V30 8 C -3.9729 2.3293 0.0 0
M  V30 9 N -2.6959 4.5523 0.0 0
M  V30 10 C -4.0084 5.3091 0.0 0
M  V30 11 C -1.4543 5.3091 0.0 0
M  V30 12 O -4.0439 6.8226 0.0 0
M  V30 13 N -5.3209 4.5996 0.0 0
M  V30 14 C -6.6334 5.3564 0.0 0
M  V30 15 C -7.9459 4.6469 0.0 0
M  V30 16 C -6.6689 6.8699 0.0 0
M  V30 17 C -9.2584 5.4037 0.0 0
M  V30 18 C -7.9814 7.6266 0.0 0
M  V30 19 C -10.5709 4.6942 0.0 0
M  V30 20 C -9.2939 6.9172 0.0 0
M  V30 21 C -10.7601 3.2635 0.0 0
M  V30 22 C -11.9543 5.3445 0.0 0
M  V30 23 N -12.2381 2.9915 0.0 0
M  V30 24 C -12.9712 4.2922 0.0 0
M  V30 25 N -14.4729 4.4814 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 1 9 11
M  V30 11 2 10 12
M  V30 12 1 10 13
M  V30 13 1 13 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 2 19 21
M  V30 21 1 19 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 1 24 25
M  V30 25 1 7 8
M  V30 26 1 18 20
M  V30 27 2 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00179001.cdx

>  <name>
US20220000118A1-20220106-C00156

>  <Row No>
301

$$$$
US20220000118A1-20220106-C00157
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 33 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4658 0.0 0
M  V30 3 N 1.2255 -2.1867 0.0 0
M  V30 4 N -1.3697 -2.1867 0.0 0
M  V30 5 C 1.1894 -3.6525 0.0 0
M  V30 6 C 2.4871 -1.4057 0.0 0
M  V30 7 C -2.7033 -1.4057 0.0 0
M  V30 8 C 2.451 -4.3734 0.0 0
M  V30 9 C -0.1441 -4.3734 0.0 0
M  V30 10 C 3.7486 -2.1266 0.0 0
M  V30 11 C 2.451 0.1321 0.0 0
M  V30 12 C -4.037 -2.1266 0.0 0
M  V30 13 C -2.7394 0.1321 0.0 0
M  V30 14 C 2.415 -5.8392 0.0 0
M  V30 15 C -0.1802 -5.8392 0.0 0
M  V30 16 C 5.0102 -1.3456 0.0 0
M  V30 17 C 3.7126 0.9251 0.0 0
M  V30 18 C -5.3707 -1.3456 0.0 0
M  V30 19 C -4.073 0.9251 0.0 0
M  V30 20 C 1.0813 -6.5601 0.0 0
M  V30 21 C 3.6765 -6.5601 0.0 0
M  V30 22 C 4.9742 0.1922 0.0 0
M  V30 23 C -6.7043 -2.0665 0.0 0
M  V30 24 C -5.4067 0.1922 0.0 0
M  V30 25 C 1.0453 -8.026 0.0 0
M  V30 26 C -6.8966 -3.5203 0.0 0
M  V30 27 C -8.1101 -1.4057 0.0 0
M  V30 28 N -8.3984 -3.7967 0.0 0
M  V30 29 C -9.1434 -2.475 0.0 0
M  V30 30 N -10.6693 -2.2828 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 6 11
M  V30 11 2 7 12
M  V30 12 1 7 13
M  V30 13 1 8 14
M  V30 14 2 9 15
M  V30 15 1 10 16
M  V30 16 2 11 17
M  V30 17 1 12 18
M  V30 18 2 13 19
M  V30 19 2 14 20
M  V30 20 1 14 21
M  V30 21 2 16 22
M  V30 22 1 18 23
M  V30 23 2 18 24
M  V30 24 1 20 25
M  V30 25 2 23 26
M  V30 26 1 23 27
M  V30 27 1 26 28
M  V30 28 1 27 29
M  V30 29 1 29 30
M  V30 30 1 15 20
M  V30 31 1 17 22
M  V30 32 1 19 24
M  V30 33 2 28 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00180001.cdx

>  <name>
US20220000118A1-20220106-C00157

>  <Row No>
302

$$$$
US20220000118A1-20220106-C00158
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.9523 1.1308 0.0 0
M  V30 3 C 2.3689 0.857 0.0 0
M  V30 4 C 0.4523 2.5831 0.0 0
M  V30 5 Cl 2.7974 -0.5237 0.0 0
M  V30 6 C 3.3212 1.9879 0.0 0
M  V30 7 C 1.4046 3.714 0.0 0
M  V30 8 C 2.8212 3.4402 0.0 0
M  V30 9 N 0.9047 5.1663 0.0 0
M  V30 10 C -0.5832 5.5115 0.0 0
M  V30 11 O -1.0832 6.9638 0.0 0
M  V30 12 N -1.607 4.4521 0.0 0
M  V30 13 C -3.095 4.7973 0.0 0
M  V30 14 C -4.1188 3.7378 0.0 0
M  V30 15 C -3.595 6.2496 0.0 0
M  V30 16 C -5.6068 4.083 0.0 0
M  V30 17 C -5.083 6.5948 0.0 0
M  V30 18 C -6.6305 3.0236 0.0 0
M  V30 19 C -6.1067 5.5353 0.0 0
M  V30 20 N -8.1423 3.214 0.0 0
M  V30 21 C -6.3567 1.607 0.0 0
M  V30 22 C -8.7971 1.8927 0.0 0
M  V30 23 C -8.9161 4.5354 0.0 0
M  V30 24 N -7.6781 0.8928 0.0 0
M  V30 25 N -10.2851 1.6189 0.0 0
M  V30 26 C -10.4398 4.5711 0.0 0
M  V30 27 C -8.2018 5.8567 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 1 20 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 23 27
M  V30 27 1 7 8
M  V30 28 1 17 19
M  V30 29 2 22 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00181001.cdx

>  <name>
US20220000118A1-20220106-C00158

>  <Row No>
303

$$$$
US20220000118A1-20220106-C00159
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.9523 1.1309 0.0 0
M  V30 3 C 2.369 0.8571 0.0 0
M  V30 4 C 0.4523 2.5833 0.0 0
M  V30 5 C 3.3214 1.9881 0.0 0
M  V30 6 C 1.4047 3.7143 0.0 0
M  V30 7 Cl 4.7381 1.7143 0.0 0
M  V30 8 C 2.8214 3.4405 0.0 0
M  V30 9 N 0.9047 5.1667 0.0 0
M  V30 10 C -0.5833 5.5119 0.0 0
M  V30 11 O -1.0833 6.9643 0.0 0
M  V30 12 N -1.6071 4.4524 0.0 0
M  V30 13 C -3.0952 4.7976 0.0 0
M  V30 14 C -4.119 3.7381 0.0 0
M  V30 15 C -3.5952 6.25 0.0 0
M  V30 16 C -5.6072 4.0833 0.0 0
M  V30 17 C -5.0833 6.5953 0.0 0
M  V30 18 C -6.631 3.0238 0.0 0
M  V30 19 C -6.1072 5.5357 0.0 0
M  V30 20 N -8.1429 3.2143 0.0 0
M  V30 21 C -6.3572 1.6071 0.0 0
M  V30 22 C -8.7977 1.8928 0.0 0
M  V30 23 C -8.9167 4.5357 0.0 0
M  V30 24 N -7.6786 0.8928 0.0 0
M  V30 25 N -10.2858 1.619 0.0 0
M  V30 26 C -10.4405 4.5714 0.0 0
M  V30 27 C -8.2024 5.8572 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 1 20 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 23 27
M  V30 27 1 6 8
M  V30 28 1 17 19
M  V30 29 2 22 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00182001.cdx

>  <name>
US20220000118A1-20220106-C00159

>  <Row No>
304

$$$$
US20220000118A1-20220106-C00160
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.9473 1.1367 0.0 0
M  V30 3 C 2.3682 0.8525 0.0 0
M  V30 4 C 0.4499 2.5814 0.0 0
M  V30 5 Cl 2.7945 -0.521 0.0 0
M  V30 6 C 3.3155 1.9893 0.0 0
M  V30 7 C 1.3972 3.7181 0.0 0
M  V30 8 C 2.8182 3.434 0.0 0
M  V30 9 N 0.8999 5.1628 0.0 0
M  V30 10 C -0.592 5.518 0.0 0
M  V30 11 O -1.0894 6.9627 0.0 0
M  V30 12 N -1.6104 4.4523 0.0 0
M  V30 13 C -3.1024 4.8076 0.0 0
M  V30 14 C -4.1208 3.7418 0.0 0
M  V30 15 C -3.5997 6.2522 0.0 0
M  V30 16 C -5.6128 4.0971 0.0 0
M  V30 17 C -5.0918 6.6074 0.0 0
M  V30 18 C -6.6311 3.0313 0.0 0
M  V30 19 C -6.1101 5.5417 0.0 0
M  V30 20 N -8.1468 3.2208 0.0 0
M  V30 21 C -6.3469 1.6104 0.0 0
M  V30 22 C -8.7981 1.8946 0.0 0
M  V30 23 C -8.9165 4.547 0.0 0
M  V30 24 N -7.6732 0.8881 0.0 0
M  V30 25 N -10.2901 1.6104 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 1 20 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 7 8
M  V30 26 1 17 19
M  V30 27 2 22 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00183001.cdx

>  <name>
US20220000118A1-20220106-C00160

>  <Row No>
305

$$$$
US20220000118A1-20220106-C00161
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0358 -1.4589 0.0 0
M  V30 3 N -1.3633 -2.1884 0.0 0
M  V30 4 N 1.2197 -2.1884 0.0 0
M  V30 5 C -2.6907 -1.3991 0.0 0
M  V30 6 C 2.4754 -1.3991 0.0 0
M  V30 7 C -4.0181 -2.1286 0.0 0
M  V30 8 C -2.7266 0.1315 0.0 0
M  V30 9 C 3.7311 -2.1286 0.0 0
M  V30 10 C -5.3455 -1.3393 0.0 0
M  V30 11 C -4.054 0.9088 0.0 0
M  V30 12 C 4.9868 -1.3393 0.0 0
M  V30 13 C -6.673 -2.0688 0.0 0
M  V30 14 C -5.3814 0.1913 0.0 0
M  V30 15 C 6.2425 -2.0688 0.0 0
M  V30 16 C -6.8643 -3.5158 0.0 0
M  V30 17 C -8.0722 -1.4111 0.0 0
M  V30 18 C 7.4981 -1.2915 0.0 0
M  V30 19 N -8.3592 -3.7909 0.0 0
M  V30 20 C -9.1006 -2.4754 0.0 0
M  V30 21 C 8.7538 -2.021 0.0 0
M  V30 22 N -10.6194 -2.2841 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 2 10 14
M  V30 14 1 12 15
M  V30 15 2 13 16
M  V30 16 1 13 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 11 14
M  V30 23 2 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00184001.cdx

>  <name>
US20220000118A1-20220106-C00161

>  <Row No>
306

$$$$
US20220000118A1-20220106-C00162
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4603 0.0 0
M  V30 3 N -1.3646 -2.1785 0.0 0
M  V30 4 N 1.2209 -2.1785 0.0 0
M  V30 5 C -2.6933 -1.4005 0.0 0
M  V30 6 C 1.185 -3.6389 0.0 0
M  V30 7 C -4.022 -2.1187 0.0 0
M  V30 8 C -2.7292 0.1316 0.0 0
M  V30 9 C -0.1436 -4.3571 0.0 0
M  V30 10 C 2.4419 -4.3571 0.0 0
M  V30 11 C -5.3507 -1.3526 0.0 0
M  V30 12 C -4.0579 0.9097 0.0 0
M  V30 13 C -0.1795 -5.8175 0.0 0
M  V30 14 C 2.406 -5.8175 0.0 0
M  V30 15 C -6.6794 -2.0708 0.0 0
M  V30 16 C -5.3866 0.1795 0.0 0
M  V30 17 C 1.0773 -6.5477 0.0 0
M  V30 18 C -6.8709 -3.5192 0.0 0
M  V30 19 C -8.0799 -1.4124 0.0 0
M  V30 20 N -8.3672 -3.7945 0.0 0
M  V30 21 C -9.1094 -2.4778 0.0 0
M  V30 22 N -10.6416 -2.4419 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 1 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 21 22
M  V30 22 1 12 16
M  V30 23 1 14 17
M  V30 24 2 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00185001.cdx

>  <name>
US20220000118A1-20220106-C00162

>  <Row No>
307

$$$$
US20220000118A1-20220106-C00163
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.2501 0.7619 0.0 0
M  V30 3 C 2.5002 0.0357 0.0 0
M  V30 4 C 1.2143 2.2859 0.0 0
M  V30 5 Cl 2.4644 -1.4167 0.0 0
M  V30 6 C 3.7503 0.7976 0.0 0
M  V30 7 C 2.4644 3.0478 0.0 0
M  V30 8 C 3.7146 2.3216 0.0 0
M  V30 9 N 2.4287 4.5718 0.0 0
M  V30 10 C 1.1072 5.3337 0.0 0
M  V30 11 S 1.0715 6.8577 0.0 0
M  V30 12 N -0.2143 4.6194 0.0 0
M  V30 13 C -1.5358 5.3814 0.0 0
M  V30 14 C -2.8573 4.667 0.0 0
M  V30 15 C -1.5715 6.9053 0.0 0
M  V30 16 C -4.1789 5.429 0.0 0
M  V30 17 C -2.8931 7.6673 0.0 0
M  V30 18 C -5.5004 4.7146 0.0 0
M  V30 19 C -4.2146 6.9529 0.0 0
M  V30 20 C -5.6909 3.274 0.0 0
M  V30 21 C -6.8934 5.3695 0.0 0
M  V30 22 N -7.1791 3.0002 0.0 0
M  V30 23 C -7.9173 4.3098 0.0 0
M  V30 24 N -9.4293 4.5003 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 7 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00186001.cdx

>  <name>
US20220000118A1-20220106-C00163

>  <Row No>
308

$$$$
US20220000118A1-20220106-C00164
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4644 0.0 0
M  V30 3 N -1.3683 -2.1966 0.0 0
M  V30 4 N 1.2243 -2.1966 0.0 0
M  V30 5 C -2.7007 -1.4164 0.0 0
M  V30 6 C 2.4847 -1.4164 0.0 0
M  V30 7 C -4.0331 -2.1486 0.0 0
M  V30 8 C -2.7367 0.12 0.0 0
M  V30 9 C 3.745 -2.1486 0.0 0
M  V30 10 C 2.4486 0.12 0.0 0
M  V30 11 C -5.3655 -1.3683 0.0 0
M  V30 12 C -4.0691 0.9002 0.0 0
M  V30 13 C 5.0054 -1.3683 0.0 0
M  V30 14 C 3.709 0.9002 0.0 0
M  V30 15 C -6.6979 -2.1006 0.0 0
M  V30 16 C -5.4015 0.168 0.0 0
M  V30 17 C 6.2657 -2.1006 0.0 0
M  V30 18 C 4.9694 0.168 0.0 0
M  V30 19 C -6.8899 -3.553 0.0 0
M  V30 20 C -8.1023 -1.4404 0.0 0
M  V30 21 C 6.3858 -3.553 0.0 0
M  V30 22 C 7.5981 -1.4404 0.0 0
M  V30 23 N -8.3903 -3.829 0.0 0
M  V30 24 C -9.1346 -2.5087 0.0 0
M  V30 25 N 7.8142 -3.829 0.0 0
M  V30 26 C 8.5584 -2.5087 0.0 0
M  V30 27 N -10.671 -2.4727 0.0 0
M  V30 28 N 10.0108 -2.3166 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 2 17 21
M  V30 21 1 17 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 24 27
M  V30 27 1 26 28
M  V30 28 1 12 16
M  V30 29 1 14 18
M  V30 30 2 23 24
M  V30 31 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00187001.cdx

>  <name>
US20220000118A1-20220106-C00164

>  <Row No>
309

$$$$
US20220000118A1-20220106-C00165
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0362 1.5448 0.0 0
M  V30 3 C -1.3758 2.3292 0.0 0
M  V30 4 C 1.231 2.3292 0.0 0
M  V30 5 C -2.7154 1.593 0.0 0
M  V30 6 C 2.4982 1.593 0.0 0
M  V30 7 C -2.7516 0.1206 0.0 0
M  V30 8 C -4.0551 2.3775 0.0 0
M  V30 9 C 2.462 0.1206 0.0 0
M  V30 10 C 3.7654 2.3775 0.0 0
M  V30 11 C -4.0913 -0.6034 0.0 0
M  V30 12 C -5.3947 1.6413 0.0 0
M  V30 13 C 3.7292 -0.6034 0.0 0
M  V30 14 C 5.0326 1.6413 0.0 0
M  V30 15 C -5.4309 0.181 0.0 0
M  V30 16 C 4.9964 0.181 0.0 0
M  V30 17 C -6.7705 -0.5551 0.0 0
M  V30 18 C 6.2636 -0.5551 0.0 0
M  V30 19 C -6.9636 -2.0154 0.0 0
M  V30 20 C -8.1826 0.1086 0.0 0
M  V30 21 C 6.3843 -2.0154 0.0 0
M  V30 22 C 7.6033 0.1086 0.0 0
M  V30 23 N -8.4722 -2.293 0.0 0
M  V30 24 C -9.2205 -0.9655 0.0 0
M  V30 25 N 7.8205 -2.293 0.0 0
M  V30 26 C 8.5688 -0.9655 0.0 0
M  V30 27 N -10.7653 -0.9292 0.0 0
M  V30 28 N 10.0291 -0.7724 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 11 15
M  V30 15 2 13 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 17 20
M  V30 20 2 18 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 24 27
M  V30 27 1 26 28
M  V30 28 1 12 15
M  V30 29 1 14 16
M  V30 30 2 23 24
M  V30 31 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00188001.cdx

>  <name>
US20220000118A1-20220106-C00165

>  <Row No>
310

$$$$
US20220000118A1-20220106-C00166
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 33 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4665 0.0 0
M  V30 3 N -1.3704 -2.1998 0.0 0
M  V30 4 N 1.2261 -2.1998 0.0 0
M  V30 5 C -2.7047 -1.4184 0.0 0
M  V30 6 C 2.4883 -1.4184 0.0 0
M  V30 7 C -4.039 -2.1517 0.0 0
M  V30 8 C -2.7408 0.1202 0.0 0
M  V30 9 C 3.7505 -2.1517 0.0 0
M  V30 10 C 2.4523 0.1202 0.0 0
M  V30 11 C -5.3734 -1.3704 0.0 0
M  V30 12 C -4.0751 0.9015 0.0 0
M  V30 13 C 5.0127 -1.3704 0.0 0
M  V30 14 C 3.7145 0.9015 0.0 0
M  V30 15 C -6.7077 -2.1036 0.0 0
M  V30 16 C -5.4094 0.1682 0.0 0
M  V30 17 C 6.275 -2.1036 0.0 0
M  V30 18 C 4.9767 0.1682 0.0 0
M  V30 19 C -6.9001 -3.5582 0.0 0
M  V30 20 C -8.1142 -1.4425 0.0 0
M  V30 21 C 6.3952 -3.5582 0.0 0
M  V30 22 C 7.6093 -1.4425 0.0 0
M  V30 23 N -8.4027 -3.8347 0.0 0
M  V30 24 C -5.8302 -4.5199 0.0 0
M  V30 25 C -9.148 -2.5124 0.0 0
M  V30 26 N 7.8257 -3.8347 0.0 0
M  V30 27 C 5.2532 -4.5199 0.0 0
M  V30 28 C 8.571 -2.5124 0.0 0
M  V30 29 N -10.6867 -2.4763 0.0 0
M  V30 30 N 10.0255 -2.32 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 2 17 21
M  V30 21 1 17 22
M  V30 22 1 19 23
M  V30 23 1 19 24
M  V30 24 1 20 25
M  V30 25 1 21 26
M  V30 26 1 21 27
M  V30 27 1 22 28
M  V30 28 1 25 29
M  V30 29 1 28 30
M  V30 30 1 12 16
M  V30 31 1 14 18
M  V30 32 2 23 25
M  V30 33 2 26 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00189001.cdx

>  <name>
US20220000118A1-20220106-C00166

>  <Row No>
311

$$$$
US20220000118A1-20220106-C00167
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0361 1.5403 0.0 0
M  V30 3 C 1.2274 2.3225 0.0 0
M  V30 4 C -1.3718 2.3225 0.0 0
M  V30 5 C 2.491 1.5884 0.0 0
M  V30 6 C -2.7076 1.5884 0.0 0
M  V30 7 C 3.7546 2.3707 0.0 0
M  V30 8 C 2.4549 0.1203 0.0 0
M  V30 9 C -2.7437 0.1203 0.0 0
M  V30 10 C -4.0434 2.3707 0.0 0
M  V30 11 C 5.0181 1.6366 0.0 0
M  V30 12 C 3.7185 -0.6017 0.0 0
M  V30 13 C -4.0795 -0.6017 0.0 0
M  V30 14 C -5.3792 1.6366 0.0 0
M  V30 15 C 6.2817 2.4188 0.0 0
M  V30 16 C 4.982 0.1684 0.0 0
M  V30 17 C -5.4153 0.1684 0.0 0
M  V30 18 N 7.6175 1.8291 0.0 0
M  V30 19 C 6.4021 3.9471 0.0 0
M  V30 20 C -6.751 -0.5535 0.0 0
M  V30 21 C 8.5802 2.9724 0.0 0
M  V30 22 N 7.8341 4.2961 0.0 0
M  V30 23 C -6.9436 -2.0096 0.0 0
M  V30 24 C -8.159 0.1083 0.0 0
M  V30 25 N 10.0363 2.852 0.0 0
M  V30 26 N -8.4478 -2.2864 0.0 0
M  V30 27 C -9.1939 -0.9627 0.0 0
M  V30 28 N -10.7223 -0.7701 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 1 15 18
M  V30 18 2 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 2 20 23
M  V30 23 1 20 24
M  V30 24 1 21 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 27 28
M  V30 28 1 12 16
M  V30 29 1 14 17
M  V30 30 2 21 22
M  V30 31 2 26 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00190001.cdx

>  <name>
US20220000118A1-20220106-C00167

>  <Row No>
312

$$$$
US20220000118A1-20220106-C00168
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 34 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0361 -1.4694 0.0 0
M  V30 3 N 1.2285 -2.1921 0.0 0
M  V30 4 N -1.373 -2.1921 0.0 0
M  V30 5 C 1.1924 -3.6615 0.0 0
M  V30 6 C -2.71 -1.4092 0.0 0
M  V30 7 C 2.457 -4.3962 0.0 0
M  V30 8 C -0.1445 -4.3962 0.0 0
M  V30 9 C -4.0469 -2.1318 0.0 0
M  V30 10 C -2.7461 0.1324 0.0 0
M  V30 11 C 2.4209 -5.8657 0.0 0
M  V30 12 C -0.1806 -5.8657 0.0 0
M  V30 13 C -5.3839 -1.3369 0.0 0
M  V30 14 C -4.0831 0.9274 0.0 0
M  V30 15 C 1.084 -6.5883 0.0 0
M  V30 16 C 3.6856 -6.5883 0.0 0
M  V30 17 C -6.7208 -2.0596 0.0 0
M  V30 18 C -5.42 0.2047 0.0 0
M  V30 19 C 1.0478 -8.0578 0.0 0
M  V30 20 C 3.6495 -8.0578 0.0 0
M  V30 21 C 5.0828 -6.0825 0.0 0
M  V30 22 C -6.9135 -3.517 0.0 0
M  V30 23 C -8.13 -1.3971 0.0 0
M  V30 24 C 2.3125 -8.7925 0.0 0
M  V30 25 N 5.0466 -8.4914 0.0 0
M  V30 26 C 5.9259 -7.2628 0.0 0
M  V30 27 N -8.4191 -3.794 0.0 0
M  V30 28 C -9.1659 -2.4691 0.0 0
M  V30 29 N 7.3953 -7.2267 0.0 0
M  V30 30 N -10.6955 -2.2764 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 11 15
M  V30 15 1 11 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 1 16 21
M  V30 21 2 17 22
M  V30 22 1 17 23
M  V30 23 1 19 24
M  V30 24 1 20 25
M  V30 25 1 21 26
M  V30 26 1 22 27
M  V30 27 1 23 28
M  V30 28 1 26 29
M  V30 29 1 28 30
M  V30 30 1 12 15
M  V30 31 1 14 18
M  V30 32 1 20 24
M  V30 33 2 25 26
M  V30 34 2 27 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00191001.cdx

>  <name>
US20220000118A1-20220106-C00168

>  <Row No>
313

$$$$
US20220000118A1-20220106-C00169
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 34 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0362 1.5465 0.0 0
M  V30 3 C 1.2324 2.3319 0.0 0
M  V30 4 C -1.3774 2.3319 0.0 0
M  V30 5 C 2.501 1.5949 0.0 0
M  V30 6 C -2.7185 1.5949 0.0 0
M  V30 7 C 2.4648 0.1208 0.0 0
M  V30 8 C 3.7697 2.3802 0.0 0
M  V30 9 C -2.7548 0.1208 0.0 0
M  V30 10 C -4.0597 2.3802 0.0 0
M  V30 11 C 3.7335 -0.6041 0.0 0
M  V30 12 C 5.0384 1.6432 0.0 0
M  V30 13 C -4.0959 -0.6041 0.0 0
M  V30 14 C -5.4009 1.6432 0.0 0
M  V30 15 C 5.0021 0.1812 0.0 0
M  V30 16 C 3.6972 -2.0782 0.0 0
M  V30 17 C -5.4371 0.1812 0.0 0
M  V30 18 C 6.2708 -0.5437 0.0 0
M  V30 19 N 2.5494 -3.0448 0.0 0
M  V30 20 C 4.9659 -2.8152 0.0 0
M  V30 21 C -6.7783 -0.5437 0.0 0
M  V30 22 C 6.2346 -2.0177 0.0 0
M  V30 23 C 3.1414 -4.3859 0.0 0
M  V30 24 N 4.6155 -4.253 0.0 0
M  V30 25 C -6.9716 -2.0057 0.0 0
M  V30 26 C -8.1919 0.1208 0.0 0
M  V30 27 N 2.3561 -5.6546 0.0 0
M  V30 28 N -8.4819 -2.2836 0.0 0
M  V30 29 C -9.231 -0.9545 0.0 0
M  V30 30 N -10.7655 -0.7612 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 11 15
M  V30 15 1 11 16
M  V30 16 2 13 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 2 16 20
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 2 21 25
M  V30 25 1 21 26
M  V30 26 1 23 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 29 30
M  V30 30 1 12 15
M  V30 31 1 14 17
M  V30 32 1 20 22
M  V30 33 2 23 24
M  V30 34 2 28 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00192001.cdx

>  <name>
US20220000118A1-20220106-C00169

>  <Row No>
314

$$$$
US20220000118A1-20220106-C00170
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 34 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0362 1.5463 0.0 0
M  V30 3 C 1.2322 2.3316 0.0 0
M  V30 4 C -1.3772 2.3316 0.0 0
M  V30 5 C 2.5008 1.6067 0.0 0
M  V30 6 C -2.7182 1.6067 0.0 0
M  V30 7 C 2.4645 0.1328 0.0 0
M  V30 8 C 3.7693 2.392 0.0 0
M  V30 9 C -2.7545 0.1328 0.0 0
M  V30 10 C -4.0592 2.392 0.0 0
M  V30 11 C 3.733 -0.5919 0.0 0
M  V30 12 C 5.0378 1.6672 0.0 0
M  V30 13 C -4.0955 -0.5919 0.0 0
M  V30 14 C -5.4002 1.6672 0.0 0
M  V30 15 C 5.0016 0.1932 0.0 0
M  V30 16 C 3.6968 -2.0658 0.0 0
M  V30 17 C -5.4365 0.1932 0.0 0
M  V30 18 C 6.2701 -0.5436 0.0 0
M  V30 19 N 2.5491 -3.0323 0.0 0
M  V30 20 C 4.9653 -2.8028 0.0 0
M  V30 21 C -6.7775 -0.5436 0.0 0
M  V30 22 C 6.2338 -2.0175 0.0 0
M  V30 23 C 3.1411 -4.3733 0.0 0
M  V30 24 N 4.615 -4.2404 0.0 0
M  V30 25 C -6.9708 -2.0054 0.0 0
M  V30 26 C -8.191 0.1208 0.0 0
M  V30 27 N 2.3558 -5.6419 0.0 0
M  V30 28 N -8.4809 -2.2833 0.0 0
M  V30 29 C -9.23 -0.9544 0.0 0
M  V30 30 N -10.7643 -0.7611 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 16 19
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 2 21 25
M  V30 25 1 21 26
M  V30 26 1 23 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 29 30
M  V30 30 1 12 15
M  V30 31 1 14 17
M  V30 32 2 20 22
M  V30 33 2 23 24
M  V30 34 2 28 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00193001.cdx

>  <name>
US20220000118A1-20220106-C00170

>  <Row No>
315

$$$$
US20220000118A1-20220106-C00171
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4631 0.0 0
M  V30 3 N -1.3672 -2.1947 0.0 0
M  V30 4 N 1.2233 -2.1947 0.0 0
M  V30 5 C -2.6984 -1.4032 0.0 0
M  V30 6 C 1.1873 -3.6579 0.0 0
M  V30 7 C -4.0297 -2.1348 0.0 0
M  V30 8 C -2.7344 0.1319 0.0 0
M  V30 9 C -0.1439 -4.3775 0.0 0
M  V30 10 C 2.4466 -4.3775 0.0 0
M  V30 11 C -5.3609 -1.3432 0.0 0
M  V30 12 C -4.0657 0.9114 0.0 0
M  V30 13 C -0.1798 -5.8407 0.0 0
M  V30 14 C 2.4106 -5.8407 0.0 0
M  V30 15 C -6.6922 -2.0748 0.0 0
M  V30 16 C -5.3969 0.1918 0.0 0
M  V30 17 C 1.0793 -6.5603 0.0 0
M  V30 18 C -6.8841 -3.526 0.0 0
M  V30 19 C -8.0954 -1.4152 0.0 0
M  V30 20 C 1.0434 -8.0234 0.0 0
M  V30 21 N -8.3832 -3.8018 0.0 0
M  V30 22 C -9.1268 -2.4826 0.0 0
M  V30 23 C 2.3027 -8.755 0.0 0
M  V30 24 N -10.65 -2.2907 0.0 0
M  V30 25 C 3.562 -7.9635 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 12 16
M  V30 26 1 14 17
M  V30 27 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00196001.cdx

>  <name>
US20220000118A1-20220106-C00171

>  <Row No>
316

$$$$
US20220000118A1-20220106-C00172
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4662 0.0 0
M  V30 3 N -1.3701 -2.1874 0.0 0
M  V30 4 N 1.2259 -2.1874 0.0 0
M  V30 5 C -2.7042 -1.4182 0.0 0
M  V30 6 C 2.4878 -1.4182 0.0 0
M  V30 7 C -4.0382 -2.1393 0.0 0
M  V30 8 C -2.7402 0.1201 0.0 0
M  V30 9 C 3.7498 -2.1393 0.0 0
M  V30 10 C 2.4518 0.1201 0.0 0
M  V30 11 C -5.3723 -1.3581 0.0 0
M  V30 12 C -4.0743 0.9014 0.0 0
M  V30 13 C 5.0118 -1.3581 0.0 0
M  V30 14 C 3.7137 0.9014 0.0 0
M  V30 15 C -6.7064 -2.0792 0.0 0
M  V30 16 C -5.4084 0.1802 0.0 0
M  V30 17 C 6.2737 -2.0792 0.0 0
M  V30 18 C 4.9757 0.1802 0.0 0
M  V30 19 C -6.8987 -3.5335 0.0 0
M  V30 20 C -8.1126 -1.4182 0.0 0
M  V30 21 C 6.3939 -3.5335 0.0 0
M  V30 22 C 7.6078 -1.4182 0.0 0
M  V30 23 N -8.4011 -3.8099 0.0 0
M  V30 24 C -9.1462 -2.4878 0.0 0
M  V30 25 N 7.8242 -3.8099 0.0 0
M  V30 26 C 8.5693 -2.4878 0.0 0
M  V30 27 N -10.6846 -2.4518 0.0 0
M  V30 28 N 10.0236 -2.2955 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 2 17 21
M  V30 21 1 17 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 24 27
M  V30 27 1 26 28
M  V30 28 1 12 16
M  V30 29 1 14 18
M  V30 30 2 23 24
M  V30 31 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00197001.cdx

>  <name>
US20220000118A1-20220106-C00172

>  <Row No>
317

$$$$
US20220000118A1-20220106-C00173
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C 1.2493 0.7734 0.0 0
M  V30 3 C 2.4986 0.0475 0.0 0
M  V30 4 C 1.2136 2.2964 0.0 0
M  V30 5 C 3.748 0.8209 0.0 0
M  V30 6 C 2.4629 3.0698 0.0 0
M  V30 7 Br 4.9973 0.0951 0.0 0
M  V30 8 C 3.7123 2.344 0.0 0
M  V30 9 N 2.4272 4.5928 0.0 0
M  V30 10 C 1.1065 5.3543 0.0 0
M  V30 11 O 1.0708 6.8773 0.0 0
M  V30 12 N -0.2141 4.6404 0.0 0
M  V30 13 C -1.5349 5.4019 0.0 0
M  V30 14 C -2.8556 4.688 0.0 0
M  V30 15 C -1.5706 6.9249 0.0 0
M  V30 16 C -4.1763 5.4614 0.0 0
M  V30 17 C -2.8913 7.6983 0.0 0
M  V30 18 C -5.4971 4.7475 0.0 0
M  V30 19 C -4.212 6.9844 0.0 0
M  V30 20 C -5.6874 3.3077 0.0 0
M  V30 21 C -6.8892 5.4019 0.0 0
M  V30 22 N -7.1748 3.0341 0.0 0
M  V30 23 C -7.9125 4.3429 0.0 0
M  V30 24 N -9.4355 4.3786 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 6 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00198001.cdx

>  <name>
US20220000118A1-20220106-C00173

>  <Row No>
318

$$$$
US20220000118A1-20220106-C00174
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0362 1.5447 0.0 0
M  V30 3 C -1.3758 2.3292 0.0 0
M  V30 4 C 1.231 2.3292 0.0 0
M  V30 5 C -2.7154 1.6051 0.0 0
M  V30 6 C 2.4982 1.6051 0.0 0
M  V30 7 C -2.7516 0.1327 0.0 0
M  V30 8 C -4.055 2.3895 0.0 0
M  V30 9 C 2.462 0.1327 0.0 0
M  V30 10 C 3.7654 2.3895 0.0 0
M  V30 11 C -4.0912 -0.5913 0.0 0
M  V30 12 C -5.3946 1.6654 0.0 0
M  V30 13 C 3.7292 -0.5913 0.0 0
M  V30 14 C 5.0326 1.6654 0.0 0
M  V30 15 C -5.4308 0.181 0.0 0
M  V30 16 C 4.9964 0.181 0.0 0
M  V30 17 C -6.7705 -0.543 0.0 0
M  V30 18 C 6.2636 -0.543 0.0 0
M  V30 19 C -6.9636 -2.0033 0.0 0
M  V30 20 C -8.1825 0.1206 0.0 0
M  V30 21 C 6.3843 -2.0033 0.0 0
M  V30 22 C 7.6032 0.1206 0.0 0
M  V30 23 N -8.4721 -2.2809 0.0 0
M  V30 24 C -9.2204 -0.9534 0.0 0
M  V30 25 N 7.8204 -2.2809 0.0 0
M  V30 26 C 8.5687 -0.9534 0.0 0
M  V30 27 N -10.7652 -0.9172 0.0 0
M  V30 28 N 10.029 -0.7603 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 11 15
M  V30 15 2 13 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 17 20
M  V30 20 2 18 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 24 27
M  V30 27 1 26 28
M  V30 28 1 12 15
M  V30 29 1 14 16
M  V30 30 2 23 24
M  V30 31 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00199001.cdx

>  <name>
US20220000118A1-20220106-C00174

>  <Row No>
319

$$$$
US20220000118A1-20220106-C00175
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3158 0.7587 0.0 0
M  V30 3 C -2.6317 0.0474 0.0 0
M  V30 4 C -1.3514 2.2761 0.0 0
M  V30 5 C -3.9476 0.8061 0.0 0
M  V30 6 C -2.6673 -1.3988 0.0 0
M  V30 7 C -2.6673 3.0348 0.0 0
M  V30 8 C -3.9832 2.3235 0.0 0
M  V30 9 F -4.1847 -1.3633 0.0 0
M  V30 10 F -2.7029 -2.8451 0.0 0
M  V30 11 F -1.221 -1.3633 0.0 0
M  V30 12 N -2.7029 4.5522 0.0 0
M  V30 13 C -4.0188 5.3109 0.0 0
M  V30 14 O -4.0543 6.8284 0.0 0
M  V30 15 N -5.3346 4.5878 0.0 0
M  V30 16 C -6.6505 5.3584 0.0 0
M  V30 17 C -7.9664 4.6352 0.0 0
M  V30 18 C -6.6861 6.8758 0.0 0
M  V30 19 C -9.2823 5.3939 0.0 0
M  V30 20 C -8.002 7.6463 0.0 0
M  V30 21 C -10.5982 4.6708 0.0 0
M  V30 22 C -9.3179 6.9113 0.0 0
M  V30 23 C -10.7879 3.2363 0.0 0
M  V30 24 C -11.9852 5.3228 0.0 0
M  V30 25 N -12.2698 2.9637 0.0 0
M  V30 26 C -9.7328 2.2879 0.0 0
M  V30 27 C -13.0048 4.2677 0.0 0
M  V30 28 N -14.5222 4.3033 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 27 28
M  V30 28 1 7 8
M  V30 29 1 20 22
M  V30 30 2 25 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00200001.cdx

>  <name>
US20220000118A1-20220106-C00175

>  <Row No>
320

$$$$
US20220000118A1-20220106-C00176
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 34 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0362 1.5454 0.0 0
M  V30 3 C 1.2315 2.3302 0.0 0
M  V30 4 C -1.3764 2.3302 0.0 0
M  V30 5 C 2.4993 1.5937 0.0 0
M  V30 6 C -2.7166 1.5937 0.0 0
M  V30 7 C 2.4631 0.1207 0.0 0
M  V30 8 C 3.7671 2.3785 0.0 0
M  V30 9 C -2.7528 0.1207 0.0 0
M  V30 10 C -4.0568 2.3785 0.0 0
M  V30 11 C 3.7308 -0.6157 0.0 0
M  V30 12 C 5.0348 1.642 0.0 0
M  V30 13 C -4.0931 -0.6157 0.0 0
M  V30 14 C -5.3971 1.642 0.0 0
M  V30 15 C 4.9986 0.169 0.0 0
M  V30 16 C 3.6946 -2.0888 0.0 0
M  V30 17 C -5.4333 0.169 0.0 0
M  V30 18 C 6.2664 -0.5554 0.0 0
M  V30 19 N 2.5476 -3.0547 0.0 0
M  V30 20 C 4.9624 -2.8253 0.0 0
M  V30 21 C -6.7735 -0.5554 0.0 0
M  V30 22 C 6.2302 -2.0284 0.0 0
M  V30 23 C 3.1392 -4.3949 0.0 0
M  V30 24 N 4.6122 -4.2621 0.0 0
M  V30 25 C -6.9667 -2.0163 0.0 0
M  V30 26 C -8.1862 0.1086 0.0 0
M  V30 27 N 2.3544 -5.6627 0.0 0
M  V30 28 N -8.4759 -2.294 0.0 0
M  V30 29 C -9.2245 -0.9659 0.0 0
M  V30 30 N -10.7579 -0.7727 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 11 15
M  V30 15 1 11 16
M  V30 16 2 13 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 2 16 20
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 2 21 25
M  V30 25 1 21 26
M  V30 26 1 23 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 29 30
M  V30 30 1 12 15
M  V30 31 1 14 17
M  V30 32 1 20 22
M  V30 33 2 23 24
M  V30 34 2 28 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00201001.cdx

>  <name>
US20220000118A1-20220106-C00176

>  <Row No>
321

$$$$
US20220000118A1-20220106-C00177
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00202001.cdx

>  <name>
US20220000118A1-20220106-C00177

>  <Row No>
322

$$$$
US20220000118A1-20220106-C00179
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4639 0.0 0
M  V30 3 N -1.3679 -2.1958 0.0 0
M  V30 4 N 1.2239 -2.1958 0.0 0
M  V30 5 C -2.6758 -1.3919 0.0 0
M  V30 6 C 1.1879 -3.6597 0.0 0
M  V30 7 C -3.9837 -2.1238 0.0 0
M  V30 8 C -2.7478 0.1439 0.0 0
M  V30 9 C -0.1439 -4.3797 0.0 0
M  V30 10 C 2.4478 -4.3797 0.0 0
M  V30 11 C -5.3396 -1.3679 0.0 0
M  V30 12 C -4.1037 0.9119 0.0 0
M  V30 13 C -0.1799 -5.8436 0.0 0
M  V30 14 C 2.4118 -5.8436 0.0 0
M  V30 15 C -6.6956 -2.0638 0.0 0
M  V30 16 C -5.4116 0.1679 0.0 0
M  V30 17 C 1.0799 -6.5756 0.0 0
M  V30 18 C -6.8876 -3.5157 0.0 0
M  V30 19 C -8.0995 -1.4039 0.0 0
M  V30 20 C 1.0439 -8.0395 0.0 0
M  V30 21 N -8.3875 -3.7917 0.0 0
M  V30 22 C -9.1314 -2.4718 0.0 0
M  V30 23 C 2.3038 -8.7594 0.0 0
M  V30 24 N -10.6673 -2.5078 0.0 0
M  V30 25 C 3.5637 -7.9795 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 12 16
M  V30 26 1 14 17
M  V30 27 2 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00204001.cdx

>  <name>
US20220000118A1-20220106-C00179

>  <Row No>
323

$$$$
US20220000118A1-20220106-C00180
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4659 0.0 0
M  V30 3 N -1.3698 -2.1869 0.0 0
M  V30 4 N 1.2256 -2.1869 0.0 0
M  V30 5 C -2.6796 -1.3818 0.0 0
M  V30 6 C 2.4873 -1.4179 0.0 0
M  V30 7 C -3.9894 -2.1269 0.0 0
M  V30 8 C -2.7517 0.1562 0.0 0
M  V30 9 C 3.7491 -2.1389 0.0 0
M  V30 10 C 2.4513 0.1201 0.0 0
M  V30 11 C -5.3472 -1.3578 0.0 0
M  V30 12 C -4.1096 0.9252 0.0 0
M  V30 13 C 5.0108 -1.3578 0.0 0
M  V30 14 C 3.713 0.9012 0.0 0
M  V30 15 C -6.7051 -2.0548 0.0 0
M  V30 16 C -5.4193 0.1802 0.0 0
M  V30 17 C 6.2725 -2.0788 0.0 0
M  V30 18 C 4.9747 0.1802 0.0 0
M  V30 19 C -6.8974 -3.5087 0.0 0
M  V30 20 C -8.111 -1.3939 0.0 0
M  V30 21 C 6.3927 -3.5328 0.0 0
M  V30 22 C 7.6063 -1.4179 0.0 0
M  V30 23 N -8.3994 -3.7851 0.0 0
M  V30 24 C -9.1444 -2.4633 0.0 0
M  V30 25 N 7.8226 -3.8091 0.0 0
M  V30 26 C 8.5676 -2.4873 0.0 0
M  V30 27 N -10.6825 -2.4994 0.0 0
M  V30 28 C 10.0216 -2.4513 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 11 15
M  V30 15 2 11 16
M  V30 16 1 13 17
M  V30 17 2 13 18
M  V30 18 2 15 19
M  V30 19 1 15 20
M  V30 20 2 17 21
M  V30 21 1 17 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 24 27
M  V30 27 1 26 28
M  V30 28 1 12 16
M  V30 29 1 14 18
M  V30 30 2 23 24
M  V30 31 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00205001.cdx

>  <name>
US20220000118A1-20220106-C00180

>  <Row No>
324

$$$$
US20220000118A1-20220106-C00181
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C 1.2482 0.7727 0.0 0
M  V30 3 C 1.2126 2.2944 0.0 0
M  V30 4 C 2.4965 0.0475 0.0 0
M  V30 5 C 2.4609 3.0672 0.0 0
M  V30 6 C 3.7448 0.8203 0.0 0
M  V30 7 N 2.4252 4.5889 0.0 0
M  V30 8 C 3.7091 2.3539 0.0 0
M  V30 9 C 4.9931 0.0951 0.0 0
M  V30 10 C 1.1056 5.3616 0.0 0
M  V30 11 O 1.0699 6.8834 0.0 0
M  V30 12 N -0.2139 4.6483 0.0 0
M  V30 13 C -1.5098 5.4449 0.0 0
M  V30 14 C -2.8056 4.7078 0.0 0
M  V30 15 C -1.5811 6.9666 0.0 0
M  V30 16 C -4.149 5.4686 0.0 0
M  V30 17 C -2.9245 7.7274 0.0 0
M  V30 18 C -5.4924 4.7791 0.0 0
M  V30 19 C -4.2203 6.9904 0.0 0
M  V30 20 C -5.6826 3.3406 0.0 0
M  V30 21 C -6.8834 5.433 0.0 0
M  V30 22 N -7.1687 3.0672 0.0 0
M  V30 23 C -7.9058 4.3749 0.0 0
M  V30 24 N -9.4275 4.4106 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 6 8
M  V30 25 1 17 19
M  V30 26 2 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00206001.cdx

>  <name>
US20220000118A1-20220106-C00181

>  <Row No>
325

$$$$
US20220000118A1-20220106-C00182
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C 1.4505 0.0356 0.0 0
M  V30 3 F 1.4149 -1.4149 0.0 0
M  V30 4 F 2.9011 0.0713 0.0 0
M  V30 5 C 1.4149 1.5575 0.0 0
M  V30 6 C 2.6633 2.3304 0.0 0
M  V30 7 C 0.0951 2.3304 0.0 0
M  V30 8 C 2.6276 3.8523 0.0 0
M  V30 9 C 3.9118 1.6051 0.0 0
M  V30 10 C 0.0594 3.8523 0.0 0
M  V30 11 C 1.3079 4.6252 0.0 0
M  V30 12 N 1.2722 6.1471 0.0 0
M  V30 13 C -0.0475 6.908 0.0 0
M  V30 14 O -0.0832 8.43 0.0 0
M  V30 15 N -1.3673 6.1828 0.0 0
M  V30 16 C -2.6633 6.9794 0.0 0
M  V30 17 C -3.9593 6.2422 0.0 0
M  V30 18 C -2.7347 8.5013 0.0 0
M  V30 19 C -5.3029 7.0032 0.0 0
M  V30 20 C -4.0782 9.2623 0.0 0
M  V30 21 C -6.6465 6.3135 0.0 0
M  V30 22 C -5.3742 8.5251 0.0 0
M  V30 23 C -6.8367 4.8749 0.0 0
M  V30 24 C -8.0376 6.9675 0.0 0
M  V30 25 N -8.323 4.6014 0.0 0
M  V30 26 C -5.7785 3.9237 0.0 0
M  V30 27 C -9.0601 5.9093 0.0 0
M  V30 28 N -10.5821 5.945 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 2 7 10
M  V30 10 2 8 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 2 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 2 19 22
M  V30 22 2 21 23
M  V30 23 1 21 24
M  V30 24 1 23 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 27 28
M  V30 28 1 10 11
M  V30 29 1 20 22
M  V30 30 2 25 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00207001.cdx

>  <name>
US20220000118A1-20220106-C00182

>  <Row No>
326

$$$$
US20220000118A1-20220106-C00184
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0484 1.5332 0.0 0
M  V30 3 C -1.3879 2.3079 0.0 0
M  V30 4 C 1.1943 2.3079 0.0 0
M  V30 5 C -2.8889 1.63 0.0 0
M  V30 6 C 3.2278 1.3879 0.0 0
M  V30 7 C -2.9051 0.1936 0.0 0
M  V30 8 C -4.2446 2.3725 0.0 0
M  V30 9 C 4.3899 2.2756 0.0 0
M  V30 10 C 3.3247 -0.0322 0.0 0
M  V30 11 C -4.2124 -0.5164 0.0 0
M  V30 12 C -5.5519 1.6623 0.0 0
M  V30 13 C 5.6972 1.7269 0.0 0
M  V30 14 C 4.632 -0.581 0.0 0
M  V30 15 C -5.5681 0.2259 0.0 0
M  V30 16 C 5.794 0.3066 0.0 0
M  V30 17 C -6.9238 -0.4196 0.0 0
M  V30 18 C 7.1013 -0.242 0.0 0
M  V30 19 C -7.1175 -1.8399 0.0 0
M  V30 20 C -8.3279 0.2098 0.0 0
M  V30 21 C 7.4725 -1.6139 0.0 0
M  V30 22 C 8.2795 0.6294 0.0 0
M  V30 23 N -8.6184 -2.0981 0.0 0
M  V30 24 C -9.3447 -0.8553 0.0 0
M  V30 25 N 8.9089 -1.5978 0.0 0
M  V30 26 C 9.4254 -0.1936 0.0 0
M  V30 27 N -10.878 -0.8069 0.0 0
M  V30 28 C 10.8618 -0.1452 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 11 15
M  V30 15 2 13 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 17 20
M  V30 20 2 18 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 24 27
M  V30 27 1 26 28
M  V30 28 1 12 15
M  V30 29 1 14 16
M  V30 30 2 23 24
M  V30 31 2 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00209001.cdx

>  <name>
US20220000118A1-20220106-C00184

>  <Row No>
327

$$$$
US20220000118A1-20220106-C00186
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 34 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.048 1.5226 0.0 0
M  V30 3 C 1.186 2.2919 0.0 0
M  V30 4 C -1.3783 2.2919 0.0 0
M  V30 5 C 3.2055 1.3783 0.0 0
M  V30 6 C -2.8689 1.6188 0.0 0
M  V30 7 C 3.1574 -0.048 0.0 0
M  V30 8 C 4.4396 2.1477 0.0 0
M  V30 9 C -2.8849 0.1923 0.0 0
M  V30 10 C -4.2152 2.356 0.0 0
M  V30 11 C 4.3916 -0.7212 0.0 0
M  V30 12 C 5.6738 1.4745 0.0 0
M  V30 13 C -4.1832 -0.5128 0.0 0
M  V30 14 C -5.5135 1.6508 0.0 0
M  V30 15 C 5.6257 0.048 0.0 0
M  V30 16 C 4.3435 -2.1477 0.0 0
M  V30 17 C -5.5295 0.2243 0.0 0
M  V30 18 C 6.8598 -0.625 0.0 0
M  V30 19 N 3.1895 -3.0612 0.0 0
M  V30 20 C 5.7379 -2.9811 0.0 0
M  V30 21 C -6.8759 -0.4167 0.0 0
M  V30 22 C 6.8117 -2.0515 0.0 0
M  V30 23 C 3.4459 -4.3595 0.0 0
M  V30 24 N 5.225 -4.3274 0.0 0
M  V30 25 C -7.0682 -1.8271 0.0 0
M  V30 26 C -8.2703 0.2083 0.0 0
M  V30 27 N 2.4843 -5.4975 0.0 0
M  V30 28 N -8.5588 -2.0836 0.0 0
M  V30 29 C -9.28 -0.8494 0.0 0
M  V30 30 N -10.8027 -0.8013 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 2 11 15
M  V30 15 1 11 16
M  V30 16 2 13 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 2 16 20
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 2 21 25
M  V30 25 1 21 26
M  V30 26 1 23 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 29 30
M  V30 30 1 12 15
M  V30 31 1 14 17
M  V30 32 1 20 22
M  V30 33 2 23 24
M  V30 34 2 28 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00211001.cdx

>  <name>
US20220000118A1-20220106-C00186

>  <Row No>
328

$$$$
US20220000146A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000146A1-20220106-C00001

>  <Row No>
329

$$$$
US20220000146A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000146A1-20220106-C00002

>  <Row No>
330

$$$$
US20220000148A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.9671 1.055 0.0 0
M  V30 3 O -1.055 -0.9671 0.0 0
M  V30 4 O 0.9671 -0.9671 0.0 0
M  V30 5 O -1.055 1.055 0.0 0 CHG=-1
M  V30 6 C 0.5568 -2.3152 0.0 0 CFG=2
M  V30 7 C 1.7437 -3.0185 0.0 0
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M  V30 END ATOM
M  V30 BEGIN BOND
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M  V30 8 1 7 9
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M  V30 28 1 20 23
M  V30 29 1 22 25
M  V30 END BOND
M  V30 BEGIN COLLECTION
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Actelion Java MolfileCreator 2.0

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Actelion Java MolfileCreator 2.0

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Actelion Java MolfileCreator 2.0

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Actelion Java MolfileCreator 2.0

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Actelion Java MolfileCreator 2.0

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M  V30 25 C -1.5619 -4.971 0.0 0
M  V30 26 C -3.9523 -4.971 0.0 0
M  V30 27 C -2.0644 -3.5313 0.0 0
M  V30 28 C -0.3259 -5.6772 0.0 0
M  V30 29 C -3.5313 -3.5313 0.0 0
M  V30 30 O 0.9099 -4.8895 0.0 0
M  V30 31 O -3.0423 -12.2781 0.0 0
M  V30 32 C -1.8878 -11.3817 0.0 0
M  V30 33 C -4.2783 -11.3817 0.0 0
M  V30 34 C -2.3904 -9.942 0.0 0
M  V30 35 C -0.6519 -12.0879 0.0 0
M  V30 36 C -3.8572 -9.942 0.0 0
M  V30 37 N 0.584 -11.3002 0.0 0
M  V30 38 C 1.7384 -10.4038 0.0 0
M  V30 39 C -0.6519 -10.4038 0.0 0
M  V30 40 C 1.2359 -8.9641 0.0 0
M  V30 41 C -0.2308 -8.9641 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 3 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 9 10
M  V30 9 1 10 11
M  V30 10 1 11 12
M  V30 11 2 11 13
M  V30 12 1 12 14
M  V30 13 1 13 15
M  V30 14 1 14 16
M  V30 15 2 17 18
M  V30 16 1 18 19
M  V30 17 1 19 20
M  V30 18 2 19 21
M  V30 19 1 20 22
M  V30 20 1 21 23
M  V30 21 1 24 25
M  V30 22 1 24 26
M  V30 23 2 25 27
M  V30 24 1 25 28
M  V30 25 2 26 29
M  V30 26 1 28 30
M  V30 27 1 31 32
M  V30 28 1 31 33
M  V30 29 2 32 34
M  V30 30 1 32 35
M  V30 31 2 33 36
M  V30 32 1 35 37
M  V30 33 1 37 38
M  V30 34 1 37 39
M  V30 35 2 38 40
M  V30 36 2 39 41
M  V30 37 2 7 8
M  V30 38 2 14 15
M  V30 39 2 22 23
M  V30 40 1 27 29
M  V30 41 1 34 36
M  V30 42 1 40 41
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00056001.cdx

>  <name>
US20220000157A1-20220106-C00034

>  <Row No>
365

$$$$
US20220000157A1-20220106-C00035
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=4
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00057001.cdx

>  <name>
US20220000157A1-20220106-C00035

>  <Row No>
366

$$$$
US20220000157A1-20220106-C00036
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=5
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00058001.cdx

>  <name>
US20220000157A1-20220106-C00036

>  <Row No>
367

$$$$
US20220000157A1-20220106-C00037
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=6
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00059001.cdx

>  <name>
US20220000157A1-20220106-C00037

>  <Row No>
368

$$$$
US20220000157A1-20220106-C00038
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=8
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00060001.cdx

>  <name>
US20220000157A1-20220106-C00038

>  <Row No>
369

$$$$
US20220000157A1-20220106-C00039
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.5129 0.0354 0.0 0
M  V30 3 C -2.4112 1.2647 0.0 0 CFG=2
M  V30 4 C -2.4112 -1.1228 0.0 0
M  V30 5 C -3.8532 0.8391 0.0 0
M  V30 6 C -2.0566 2.7303 0.0 0
M  V30 7 C -3.8532 -0.6264 0.0 0
M  V30 8 C -5.1651 1.6074 0.0 0
M  V30 9 C -5.1651 -1.3474 0.0 0
M  V30 10 C -6.4771 0.8864 0.0 0 CFG=2
M  V30 11 C -5.2006 -2.7894 0.0 0
M  V30 12 C -6.4771 -0.5791 0.0 0 CFG=2
M  V30 13 C -7.99 0.9219 0.0 0
M  V30 14 C -7.99 -0.5437 0.0 0
M  V30 15 C -9.503 0.9573 0.0 0
M  V30 16 C -8.0255 2.4348 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6 CFG=3
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 10 8 CFG=3
M  V30 10 2 9 11
M  V30 11 1 12 9 CFG=1
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 10 12
M  V30 17 1 13 14
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 3 10 12)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00061001.cdx

>  <name>
US20220000157A1-20220106-C00039

>  <Row No>
370

$$$$
US20220000157A1-20220106-C00040
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.5129 0.0354 0.0 0
M  V30 3 C -2.4112 1.2647 0.0 0 CFG=2
M  V30 4 C -2.4112 -1.1228 0.0 0
M  V30 5 C -3.8532 0.8391 0.0 0
M  V30 6 C -2.0566 2.7303 0.0 0
M  V30 7 C -3.8532 -0.6264 0.0 0
M  V30 8 C -5.1651 1.6074 0.0 0
M  V30 9 C -5.1651 -1.3474 0.0 0
M  V30 10 C -6.4771 0.8864 0.0 0 CFG=1
M  V30 11 C -5.2006 -2.7894 0.0 0
M  V30 12 C -6.4771 -0.5791 0.0 0 CFG=1
M  V30 13 C -7.99 0.9219 0.0 0
M  V30 14 C -7.99 -0.5437 0.0 0
M  V30 15 C -9.503 0.9573 0.0 0
M  V30 16 C -8.0255 2.4348 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6 CFG=3
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 10 8 CFG=1
M  V30 10 2 9 11
M  V30 11 1 12 9 CFG=3
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 10 12
M  V30 17 1 13 14
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 3 10 12)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00062001.cdx

>  <name>
US20220000157A1-20220106-C00040

>  <Row No>
371

$$$$
US20220000157A1-20220106-C00041
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.4276 1.4731 0.0 0
M  V30 3 C -1.9007 1.9007 0.0 0 CFG=2
M  V30 4 C -1.9364 0.4514 0.0 0
M  V30 5 C -2.9818 2.9818 0.0 0
M  V30 6 C -0.8909 2.9818 0.0 0
M  V30 7 C -3.0174 -0.5583 0.0 0
M  V30 8 C -4.5024 3.0174 0.0 0
M  V30 9 C -4.5381 -0.5227 0.0 0
M  V30 10 C -5.5835 2.0077 0.0 0 CFG=1
M  V30 11 C -5.2984 -1.7701 0.0 0
M  V30 12 C -5.6191 0.5583 0.0 0 CFG=1
M  V30 13 C -7.1041 2.0433 0.0 0
M  V30 14 C -7.1398 0.5939 0.0 0
M  V30 15 C -8.6247 2.0789 0.0 0
M  V30 16 C -7.1398 3.5639 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 4 1 3 5
M  V30 5 1 3 6 CFG=1
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 10 8 CFG=1
M  V30 10 2 9 11
M  V30 11 1 12 9 CFG=3
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 10 12
M  V30 17 1 13 14
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 3 10 12)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00063001.cdx

>  <name>
US20220000157A1-20220106-C00041

>  <Row No>
372

$$$$
US20220000157A1-20220106-C00042
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.4276 1.4731 0.0 0
M  V30 3 C -1.9007 1.9007 0.0 0 CFG=2
M  V30 4 C -1.9364 0.4514 0.0 0
M  V30 5 C -2.9818 2.9818 0.0 0
M  V30 6 C -0.8909 2.9818 0.0 0
M  V30 7 C -3.0174 -0.5583 0.0 0
M  V30 8 C -4.5024 3.0174 0.0 0
M  V30 9 C -4.5381 -0.5227 0.0 0
M  V30 10 C -5.5835 2.0077 0.0 0 CFG=2
M  V30 11 C -5.2984 -1.7701 0.0 0
M  V30 12 C -5.6191 0.5583 0.0 0 CFG=2
M  V30 13 C -7.1041 2.0433 0.0 0
M  V30 14 C -7.1398 0.5939 0.0 0
M  V30 15 C -8.6247 2.0789 0.0 0
M  V30 16 C -7.1398 3.5639 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 4 1 3 5
M  V30 5 1 3 6 CFG=1
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 10 8 CFG=3
M  V30 10 2 9 11
M  V30 11 1 12 9 CFG=1
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 10 12
M  V30 17 1 13 14
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 3 10 12)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00064001.cdx

>  <name>
US20220000157A1-20220106-C00042

>  <Row No>
373

$$$$
US20220000157A1-20220106-C00043
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 18 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.4331 -1.4198 0.0 0 CFG=2
M  V30 3 C 1.4439 0.2406 0.0 0 CFG=2
M  V30 4 C -0.8663 0.0721 0.0 0 CFG=2
M  V30 5 C 0.9866 -1.7808 0.0 0
M  V30 6 C -1.5281 -2.4426 0.0 0
M  V30 7 C 2.1658 1.5762 0.0 0
M  V30 8 C 2.0696 -0.6979 0.0 0
M  V30 9 C -0.9024 1.6123 0.0 0 CFG=2
M  V30 10 C -2.4065 0.1082 0.0 0
M  V30 11 C 1.3958 2.9119 0.0 0
M  V30 12 C 3.6338 1.6123 0.0 0
M  V30 13 C -2.4426 1.6484 0.0 0
M  V30 14 C -0.1804 2.948 0.0 0
M  V30 15 C -3.9828 1.6845 0.0 0
M  V30 16 C -3.5376 2.7434 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 3 1 CFG=3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 2 6 CFG=3
M  V30 6 1 3 7
M  V30 7 1 3 8
M  V30 8 1 4 9
M  V30 9 1 4 10 CFG=1
M  V30 10 2 7 11
M  V30 11 1 7 12
M  V30 12 1 9 13
M  V30 13 1 9 14 CFG=3
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 5 8
M  V30 17 1 10 13
M  V30 18 1 11 14
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(4 2 3 4 9)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00065001.cdx

>  <name>
US20220000157A1-20220106-C00043

>  <Row No>
374

$$$$
US20220000157A1-20220106-C00044
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 17 19 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 2.0811 1.503 0.0 0 CFG=2
M  V30 3 C -0.4129 -1.3543 0.0 0 CFG=2
M  V30 4 C 1.3213 0.2973 0.0 0 CFG=1
M  V30 5 C 1.3213 2.8078 0.0 0
M  V30 6 C 3.485 1.5525 0.0 0
M  V30 7 C -0.8258 0.0991 0.0 0 CFG=1
M  V30 8 C 0.9414 -1.6682 0.0 0
M  V30 9 C -1.47 -2.3123 0.0 0
M  V30 10 O 2.7252 0.3468 0.0 0
M  V30 11 C 1.8829 -0.578 0.0 0
M  V30 12 C -0.1816 2.8574 0.0 0
M  V30 13 C -0.8753 1.6021 0.0 0 CFG=2
M  V30 14 C -2.3288 0.1486 0.0 0
M  V30 15 C -2.3784 1.6516 0.0 0
M  V30 16 C -3.8814 1.7012 0.0 0
M  V30 17 C -3.452 2.7087 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 2 6 CFG=3
M  V30 6 1 3 7
M  V30 7 1 3 8
M  V30 8 1 3 9 CFG=3
M  V30 9 1 4 10 CFG=3
M  V30 10 1 4 11
M  V30 11 1 5 12
M  V30 12 1 7 13
M  V30 13 1 7 14 CFG=3
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 1 15 17
M  V30 17 1 8 11
M  V30 18 1 13 12 CFG=1
M  V30 19 1 14 15
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(5 2 3 4 7 13)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00066001.cdx

>  <name>
US20220000157A1-20220106-C00044

>  <Row No>
375

$$$$
US20220000157A1-20220106-C00045
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 17 19 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 2.0811 1.503 0.0 0 CFG=2
M  V30 3 C -0.4129 -1.3543 0.0 0 CFG=2
M  V30 4 C 1.3213 0.2973 0.0 0 CFG=2
M  V30 5 C 1.3213 2.8078 0.0 0
M  V30 6 C 3.485 1.5525 0.0 0
M  V30 7 C -0.8258 0.0991 0.0 0 CFG=1
M  V30 8 C 0.9414 -1.6682 0.0 0
M  V30 9 C -1.47 -2.3123 0.0 0
M  V30 10 O 2.7252 0.3468 0.0 0
M  V30 11 C 1.8829 -0.578 0.0 0
M  V30 12 C -0.1816 2.8574 0.0 0
M  V30 13 C -0.8753 1.6021 0.0 0 CFG=2
M  V30 14 C -2.3288 0.1486 0.0 0
M  V30 15 C -2.3784 1.6516 0.0 0
M  V30 16 C -3.8814 1.7012 0.0 0
M  V30 17 C -3.452 2.7087 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 2 6 CFG=3
M  V30 6 1 3 7
M  V30 7 1 3 8
M  V30 8 1 3 9 CFG=3
M  V30 9 1 4 10 CFG=1
M  V30 10 1 4 11
M  V30 11 1 5 12
M  V30 12 1 7 13
M  V30 13 1 7 14 CFG=3
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 1 15 17
M  V30 17 1 8 11
M  V30 18 1 13 12 CFG=1
M  V30 19 1 14 15
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(5 2 3 4 7 13)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00067001.cdx

>  <name>
US20220000157A1-20220106-C00045

>  <Row No>
376

$$$$
US20220000157A1-20220106-C00046
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 17 19 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2669 0.7859 0.0 0 CFG=2
M  V30 3 C 0.9033 2.2876 0.0 0 CFG=1
M  V30 4 C 2.5339 1.5837 0.0 0
M  V30 5 C 1.2317 -0.6804 0.0 0
M  V30 6 C 1.8066 3.4959 0.0 0 CFG=1
M  V30 7 C -0.305 3.2613 0.0 0
M  V30 8 C 3.8009 0.8563 0.0 0 CFG=2
M  V30 9 C 2.4987 -1.396 0.0 0
M  V30 10 C 0.5982 4.4696 0.0 0
M  V30 11 C 3.273 3.5311 0.0 0
M  V30 12 C 3.7657 -0.61 0.0 0 CFG=2
M  V30 13 C 4.1998 2.3579 0.0 0
M  V30 14 C 5.2673 0.8915 0.0 0
M  V30 15 C -0.1759 5.8069 0.0 0
M  V30 16 C 1.3256 5.8069 0.0 0
M  V30 17 O 5.0327 -1.3256 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=3
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7 CFG=3
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 6 11 CFG=1
M  V30 11 1 8 12
M  V30 12 1 8 13
M  V30 13 1 8 14 CFG=3
M  V30 14 1 10 15
M  V30 15 1 10 16
M  V30 16 1 12 17 CFG=1
M  V30 17 1 7 10
M  V30 18 1 9 12
M  V30 19 1 11 13
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(5 2 3 6 8 12)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00068001.cdx

>  <name>
US20220000157A1-20220106-C00046

>  <Row No>
377

$$$$
US20220000157A1-20220106-C00047
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 101 111 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.1005 1.5746 0.0 0
M  V30 3 O 1.072 2.4121 0.0 0
M  V30 4 C -1.4741 2.4121 0.0 0
M  V30 5 C 1.3401 3.9198 0.0 0 CFG=1
M  V30 6 C -2.8477 1.7756 0.0 0
M  V30 7 C 2.6467 4.4893 0.0 0 CFG=1
M  V30 8 C 0.3685 5.2264 0.0 0
M  V30 9 C -4.2213 2.6132 0.0 0
M  V30 10 C -2.9482 0.402 0.0 0
M  V30 11 C 2.5462 6.0639 0.0 0 CFG=1
M  V30 12 C 3.8193 3.8528 0.0 0
M  V30 13 C 2.5462 3.1157 0.0 0
M  V30 14 C 1.139 6.533 0.0 0
M  V30 15 C 3.7187 6.9015 0.0 0
M  V30 16 C 4.9918 4.6903 0.0 0 CFG=2
M  V30 17 C 3.7187 2.4791 0.0 0
M  V30 18 C 0.0 7.6721 0.0 0
M  V30 19 C 1.4071 8.0406 0.0 0
M  V30 20 C 4.8913 6.2649 0.0 0
M  V30 21 C 4.8913 3.3167 0.0 0 CFG=2
M  V30 22 C 6.2985 5.1594 0.0 0
M  V30 23 O 6.0639 2.6802 0.0 0
M  V30 24 O 6.4325 14.4731 0.0 0
M  V30 25 C 5.0589 15.3107 0.0 0
M  V30 26 O 3.6852 14.6741 0.0 0
M  V30 27 C 4.9583 16.8853 0.0 0
M  V30 28 C 2.3116 15.5117 0.0 0 CFG=2
M  V30 29 C 2.2111 17.0863 0.0 0 CFG=2
M  V30 30 C 0.938 14.8751 0.0 0
M  V30 31 C 0.8375 16.4498 0.0 0
M  V30 32 C 2.1106 18.6609 0.0 0
M  V30 33 C 3.5177 17.5554 0.0 0
M  V30 34 C -0.4355 15.7127 0.0 0
M  V30 35 C -0.536 17.2873 0.0 0 CFG=2
M  V30 36 C 0.737 19.4985 0.0 0
M  V30 37 C -0.6365 18.862 0.0 0 CFG=2
M  V30 38 C -2.0436 16.9188 0.0 0 CFG=2
M  V30 39 C -2.1441 19.4315 0.0 0
M  V30 40 O -2.5127 15.6122 0.0 0
M  V30 41 C -3.0152 18.2254 0.0 0
M  V30 42 C -1.8761 20.9391 0.0 0
M  V30 43 C -3.2832 20.5706 0.0 0
M  V30 44 C -3.8863 14.9756 0.0 0
M  V30 45 O -3.9868 13.602 0.0 0
M  V30 46 C -5.2599 15.8132 0.0 0
M  V30 47 O -2.1441 23.3178 0.0 0
M  V30 48 C -2.2446 24.8924 0.0 0
M  V30 49 O -1.072 25.73 0.0 0
M  V30 50 C -3.6182 25.73 0.0 0
M  V30 51 C -0.804 27.2376 0.0 0 CFG=1
M  V30 52 C 0.5025 27.8072 0.0 0 CFG=1
M  V30 53 C -1.7756 28.5442 0.0 0
M  V30 54 C 0.402 29.3818 0.0 0 CFG=1
M  V30 55 C 1.6751 27.1706 0.0 0
M  V30 56 C 0.402 26.4336 0.0 0
M  V30 57 C -1.005 29.8508 0.0 0
M  V30 58 C 1.5746 30.2194 0.0 0
M  V30 59 C 2.8477 28.0082 0.0 0 CFG=2
M  V30 60 C 1.5746 25.797 0.0 0
M  V30 61 C -0.737 31.3585 0.0 0
M  V30 62 C -2.1441 30.9899 0.0 0
M  V30 63 C 2.7472 29.5828 0.0 0
M  V30 64 C 2.7472 26.6346 0.0 0 CFG=2
M  V30 65 C 4.1543 28.4772 0.0 0
M  V30 66 O 3.9198 25.998 0.0 0
M  V30 67 O -1.3401 -9.3807 0.0 0
M  V30 68 C -1.072 -7.8731 0.0 0 CFG=1
M  V30 69 C -2.7137 -10.0172 0.0 0
M  V30 70 C 0.2345 -7.3035 0.0 0 CFG=1
M  V30 71 C -2.0436 -6.5665 0.0 0
M  V30 72 C 0.134 -5.7289 0.0 0 CFG=1
M  V30 73 C 1.4071 -7.9401 0.0 0
M  V30 74 C 0.134 -8.6771 0.0 0
M  V30 75 C -1.2731 -5.2599 0.0 0
M  V30 76 C 1.3066 -4.8913 0.0 0
M  V30 77 C 2.5797 -7.1025 0.0 0 CFG=2
M  V30 78 C 1.3066 -9.3137 0.0 0
M  V30 79 C -2.4121 -4.1208 0.0 0
M  V30 80 C -1.005 -3.7522 0.0 0
M  V30 81 C 2.4791 -5.5279 0.0 0
M  V30 82 C 2.4791 -8.4761 0.0 0 CFG=2
M  V30 83 C 3.8863 -6.6335 0.0 0
M  V30 84 O 3.6517 -9.1127 0.0 0
M  V30 85 O 3.7522 34.3067 0.0 0
M  V30 86 C 2.3786 35.1443 0.0 0 CFG=2
M  V30 87 C 2.2781 36.7189 0.0 0 CFG=2
M  V30 88 C 1.005 34.5077 0.0 0
M  V30 89 C 0.9045 36.0823 0.0 0
M  V30 90 C 2.1776 38.2935 0.0 0
M  V30 91 C 3.5847 37.1879 0.0 0
M  V30 92 C -0.3685 35.3453 0.0 0
M  V30 93 C -0.469 36.9199 0.0 0 CFG=2
M  V30 94 C 0.804 39.1311 0.0 0
M  V30 95 C -0.5695 38.4945 0.0 0 CFG=2
M  V30 96 C -1.9766 36.5514 0.0 0 CFG=2
M  V30 97 C -2.0771 39.0641 0.0 0
M  V30 98 O -2.4456 35.2448 0.0 0
M  V30 99 C -2.9482 37.858 0.0 0
M  V30 100 C -1.8091 40.5717 0.0 0
M  V30 101 C -3.2162 40.2032 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=3
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 7 12 CFG=1
M  V30 12 1 7 13
M  V30 13 1 8 14
M  V30 14 1 11 15 CFG=1
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 1 14 19
M  V30 19 1 15 20
M  V30 20 1 16 21
M  V30 21 1 16 22 CFG=1
M  V30 22 1 21 23 CFG=1
M  V30 23 2 24 25
M  V30 24 1 25 26
M  V30 25 1 25 27
M  V30 26 1 28 26 CFG=1
M  V30 27 1 29 28 CFG=3
M  V30 28 1 28 30
M  V30 29 1 29 31
M  V30 30 1 29 32
M  V30 31 1 29 33
M  V30 32 1 30 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 35 37
M  V30 36 1 35 38
M  V30 37 1 37 39
M  V30 38 1 38 40 CFG=3
M  V30 39 1 38 41
M  V30 40 1 39 42
M  V30 41 1 39 43
M  V30 42 1 40 44
M  V30 43 2 44 45
M  V30 44 1 44 46
M  V30 45 2 47 48
M  V30 46 1 48 49
M  V30 47 1 48 50
M  V30 48 1 51 49 CFG=3
M  V30 49 1 51 52
M  V30 50 1 51 53
M  V30 51 1 52 54
M  V30 52 1 52 55 CFG=1
M  V30 53 1 52 56
M  V30 54 1 53 57
M  V30 55 1 54 58 CFG=1
M  V30 56 1 55 59
M  V30 57 1 56 60
M  V30 58 1 57 61
M  V30 59 1 57 62
M  V30 60 1 58 63
M  V30 61 1 59 64
M  V30 62 1 59 65 CFG=1
M  V30 63 1 64 66 CFG=1
M  V30 64 1 68 67 CFG=3
M  V30 65 1 67 69
M  V30 66 1 68 70
M  V30 67 1 68 71
M  V30 68 1 70 72
M  V30 69 1 70 73 CFG=1
M  V30 70 1 70 74
M  V30 71 1 71 75
M  V30 72 1 72 76 CFG=1
M  V30 73 1 73 77
M  V30 74 1 74 78
M  V30 75 1 75 79
M  V30 76 1 75 80
M  V30 77 1 76 81
M  V30 78 1 77 82
M  V30 79 1 77 83 CFG=1
M  V30 80 1 82 84 CFG=1
M  V30 81 1 86 85 CFG=1
M  V30 82 1 87 86 CFG=3
M  V30 83 1 86 88
M  V30 84 1 87 89
M  V30 85 1 87 90
M  V30 86 1 87 91
M  V30 87 1 88 92
M  V30 88 1 89 93
M  V30 89 1 90 94
M  V30 90 1 93 95
M  V30 91 1 93 96
M  V30 92 1 95 97
M  V30 93 1 96 98 CFG=3
M  V30 94 1 96 99
M  V30 95 1 97 100
M  V30 96 1 97 101
M  V30 97 1 11 14
M  V30 98 1 16 20
M  V30 99 1 17 21
M  V30 100 1 35 34 CFG=3
M  V30 101 1 37 36 CFG=1
M  V30 102 1 39 41
M  V30 103 1 54 57
M  V30 104 1 59 63
M  V30 105 1 60 64
M  V30 106 1 72 75
M  V30 107 1 77 81
M  V30 108 1 78 82
M  V30 109 1 93 92 CFG=3
M  V30 110 1 95 94 CFG=1
M  V30 111 1 97 99
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(25 5 7 11 16 21 28 29 35 37 38 51 52 54 59 64 68 70 72 77 82 86 87 93 95 96)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00069001.cdx

>  <name>
US20220000157A1-20220106-C00047

>  <Row No>
378

$$$$
US20220000157A1-20220106-C00048
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 83 88 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.2404 1.4825 0.0 0
M  V30 3 O -0.8815 2.6044 0.0 0
M  V30 4 C 1.4825 1.9633 0.0 0
M  V30 5 C -2.4041 2.7246 0.0 0 CFG=2
M  V30 6 C -1.803 4.0869 0.0 0
M  V30 7 C -1.6828 1.6828 0.0 0
M  V30 8 C -2.6445 5.4493 0.0 0
M  V30 9 C -0.5208 4.2071 0.0 0
M  V30 10 C -2.8047 0.8013 0.0 0
M  V30 11 C -4.1671 5.5695 0.0 0
M  V30 12 C -4.2873 1.2821 0.0 0
M  V30 13 C -5.0085 4.4475 0.0 0 CFG=1
M  V30 14 C -5.4092 0.4006 0.0 0
M  V30 15 C -5.0085 3.0051 0.0 0 CFG=1
M  V30 16 C -6.5311 4.5678 0.0 0
M  V30 17 C -6.5311 3.1253 0.0 0
M  V30 18 C -8.0537 4.688 0.0 0
M  V30 19 C -7.3725 5.9301 0.0 0
M  V30 20 O -0.641 21.7972 0.0 0
M  V30 21 C -2.1636 21.9174 0.0 0 CFG=2
M  V30 22 C -1.5626 23.2797 0.0 0
M  V30 23 C -1.4424 20.8756 0.0 0
M  V30 24 C -2.4041 24.642 0.0 0
M  V30 25 C -0.2804 23.3999 0.0 0
M  V30 26 C -2.5643 19.9941 0.0 0
M  V30 27 C -3.9267 24.7623 0.0 0
M  V30 28 C -4.0469 20.4749 0.0 0
M  V30 29 C -4.7681 23.6403 0.0 0 CFG=1
M  V30 30 C -5.1688 19.5934 0.0 0
M  V30 31 C -4.7681 22.1979 0.0 0 CFG=1
M  V30 32 C -6.2907 23.7605 0.0 0
M  V30 33 C -6.2907 22.3181 0.0 0
M  V30 34 C -7.8133 23.8807 0.0 0
M  V30 35 C -7.1321 25.1229 0.0 0
M  V30 36 O 0.641 41.03 0.0 0
M  V30 37 C -0.8815 41.1503 0.0 0 CFG=2
M  V30 38 C -1.8431 42.4324 0.0 0
M  V30 39 C -1.8431 40.1085 0.0 0
M  V30 40 C -3.3256 42.1119 0.0 0
M  V30 41 C -1.6027 43.915 0.0 0
M  V30 42 C -3.3256 40.6694 0.0 0
M  V30 43 C -4.688 42.9533 0.0 0
M  V30 44 C -4.688 40.0684 0.0 0
M  V30 45 C -6.0503 42.3523 0.0 0 CFG=1
M  V30 46 C -4.8082 38.7862 0.0 0
M  V30 47 C -6.0503 40.9098 0.0 0 CFG=1
M  V30 48 C -7.5729 42.4725 0.0 0
M  V30 49 C -7.5729 41.03 0.0 0
M  V30 50 C -9.0955 42.5927 0.0 0
M  V30 51 C -7.6931 43.9951 0.0 0
M  V30 52 O -0.641 12.5013 0.0 0
M  V30 53 C -2.1636 12.6215 0.0 0 CFG=1
M  V30 54 C -1.5626 13.9838 0.0 0
M  V30 55 C -1.4424 11.5797 0.0 0
M  V30 56 C -2.4041 15.3462 0.0 0
M  V30 57 C -0.2804 14.104 0.0 0
M  V30 58 C -2.5643 10.6982 0.0 0
M  V30 59 C -3.9267 15.4664 0.0 0
M  V30 60 C -4.0469 11.179 0.0 0
M  V30 61 C -4.7681 14.3445 0.0 0 CFG=1
M  V30 62 C -5.1688 10.2975 0.0 0
M  V30 63 C -4.7681 12.902 0.0 0 CFG=1
M  V30 64 C -6.2907 14.4647 0.0 0
M  V30 65 C -6.2907 13.0222 0.0 0
M  V30 66 C -7.8133 14.5849 0.0 0
M  V30 67 C -7.1321 15.827 0.0 0
M  V30 68 O 0.641 32.3753 0.0 0
M  V30 69 C -0.8815 32.4955 0.0 0 CFG=1
M  V30 70 C -1.8431 33.7777 0.0 0
M  V30 71 C -1.8431 31.4537 0.0 0
M  V30 72 C -3.3256 33.4571 0.0 0
M  V30 73 C -1.6027 35.2602 0.0 0
M  V30 74 C -3.3256 32.0146 0.0 0
M  V30 75 C -4.688 34.2985 0.0 0
M  V30 76 C -4.688 31.4136 0.0 0
M  V30 77 C -6.0503 33.6975 0.0 0 CFG=1
M  V30 78 C -4.8082 30.1314 0.0 0
M  V30 79 C -6.0503 32.2551 0.0 0 CFG=1
M  V30 80 C -7.5729 33.8177 0.0 0
M  V30 81 C -7.5729 32.3753 0.0 0
M  V30 82 C -9.0955 33.9379 0.0 0
M  V30 83 C -7.6931 35.3403 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=3
M  V30 5 1 5 6
M  V30 6 1 5 7
M  V30 7 2 6 8 CFG=2
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 10 12
M  V30 12 1 13 11 CFG=1
M  V30 13 2 12 14
M  V30 14 1 15 12 CFG=3
M  V30 15 1 13 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 1 21 20 CFG=3
M  V30 20 1 21 22
M  V30 21 1 21 23
M  V30 22 2 22 24
M  V30 23 1 22 25
M  V30 24 1 23 26
M  V30 25 1 24 27
M  V30 26 1 26 28
M  V30 27 1 29 27 CFG=1
M  V30 28 2 28 30
M  V30 29 1 31 28 CFG=3
M  V30 30 1 29 32
M  V30 31 1 31 33
M  V30 32 1 32 34
M  V30 33 1 32 35
M  V30 34 1 37 36 CFG=1
M  V30 35 1 37 38
M  V30 36 1 37 39
M  V30 37 2 38 40
M  V30 38 1 38 41
M  V30 39 1 39 42
M  V30 40 1 40 43
M  V30 41 1 42 44
M  V30 42 1 45 43 CFG=1
M  V30 43 2 44 46
M  V30 44 1 47 44 CFG=3
M  V30 45 1 45 48
M  V30 46 1 47 49
M  V30 47 1 48 50
M  V30 48 1 48 51
M  V30 49 1 53 52 CFG=1
M  V30 50 1 53 54
M  V30 51 1 53 55
M  V30 52 2 54 56
M  V30 53 1 54 57
M  V30 54 1 55 58
M  V30 55 1 56 59
M  V30 56 1 58 60
M  V30 57 1 61 59 CFG=1
M  V30 58 2 60 62
M  V30 59 1 63 60 CFG=3
M  V30 60 1 61 64
M  V30 61 1 63 65
M  V30 62 1 64 66
M  V30 63 1 64 67
M  V30 64 1 69 68 CFG=3
M  V30 65 1 69 70
M  V30 66 1 69 71
M  V30 67 2 70 72
M  V30 68 1 70 73
M  V30 69 1 71 74
M  V30 70 1 72 75
M  V30 71 1 74 76
M  V30 72 1 77 75 CFG=1
M  V30 73 2 76 78
M  V30 74 1 79 76 CFG=3
M  V30 75 1 77 80
M  V30 76 1 79 81
M  V30 77 1 80 82
M  V30 78 1 80 83
M  V30 79 1 13 15
M  V30 80 1 16 17
M  V30 81 1 29 31
M  V30 82 1 32 33
M  V30 83 1 45 47
M  V30 84 1 48 49
M  V30 85 1 61 63
M  V30 86 1 64 65
M  V30 87 1 77 79
M  V30 88 1 80 81
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(15 5 13 15 21 29 31 37 45 47 53 61 63 69 77 79)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00071001.cdx

>  <name>
US20220000157A1-20220106-C00048

>  <Row No>
379

$$$$
US20220000157A1-20220106-C00049
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 70 74 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.2901 1.4828 0.0 0
M  V30 3 O -0.8059 2.5789 0.0 0
M  V30 4 C 1.5795 1.9664 0.0 0
M  V30 5 C -2.3532 2.6756 0.0 0 CFG=2
M  V30 6 C -1.7407 4.0295 0.0 0
M  V30 7 C -1.6118 1.6118 0.0 0
M  V30 8 C -0.3868 4.1262 0.0 0
M  V30 9 C -2.5466 5.3834 0.0 0
M  V30 10 C -2.7078 0.7092 0.0 0
M  V30 11 C -4.094 5.4802 0.0 0
M  V30 12 C -4.1907 1.1927 0.0 0
M  V30 13 C -4.8999 4.3196 0.0 0 CFG=2
M  V30 14 C -5.2867 0.2901 0.0 0
M  V30 15 C -4.8677 2.9012 0.0 0 CFG=2
M  V30 16 C -6.4473 4.4164 0.0 0
M  V30 17 C -6.415 2.9979 0.0 0
M  V30 18 C -7.9946 4.5131 0.0 0
M  V30 19 C -7.2532 5.7703 0.0 0
M  V30 20 O -0.7736 10.8314 0.0 0
M  V30 21 C -0.4835 12.3143 0.0 0
M  V30 22 O -1.5795 13.4103 0.0 0
M  V30 23 C 0.8059 12.7978 0.0 0
M  V30 24 C -3.1269 13.507 0.0 0 CFG=1
M  V30 25 C -2.5144 14.861 0.0 0
M  V30 26 C -2.3855 12.4432 0.0 0
M  V30 27 C -1.1605 14.9577 0.0 0
M  V30 28 C -3.3203 16.2149 0.0 0
M  V30 29 C -3.4815 11.5406 0.0 0
M  V30 30 C -4.8677 16.3116 0.0 0
M  V30 31 C -4.9644 12.0242 0.0 0
M  V30 32 C -5.6736 15.1511 0.0 0 CFG=2
M  V30 33 C -6.0604 11.1215 0.0 0
M  V30 34 C -5.6413 13.7327 0.0 0 CFG=2
M  V30 35 C -7.2209 15.2478 0.0 0
M  V30 36 C -7.1887 13.8294 0.0 0
M  V30 37 C -8.7683 15.3445 0.0 0
M  V30 38 C -8.0268 16.6017 0.0 0
M  V30 39 O -0.5157 23.2102 0.0 0
M  V30 40 C -2.0631 23.3069 0.0 0 CFG=2
M  V30 41 C -1.4506 24.6609 0.0 0
M  V30 42 C -1.3216 22.2431 0.0 0
M  V30 43 C -0.0967 24.7576 0.0 0
M  V30 44 C -2.2565 26.0148 0.0 0
M  V30 45 C -2.4177 21.3405 0.0 0
M  V30 46 C -3.8039 26.1115 0.0 0
M  V30 47 C -3.9006 21.8241 0.0 0
M  V30 48 C -4.6098 24.951 0.0 0 CFG=2
M  V30 49 C -4.9966 20.9214 0.0 0
M  V30 50 C -4.5775 23.5326 0.0 0 CFG=2
M  V30 51 C -6.1571 25.0477 0.0 0
M  V30 52 C -6.1249 23.6293 0.0 0
M  V30 53 C -7.7045 25.1444 0.0 0
M  V30 54 C -6.963 26.4016 0.0 0
M  V30 55 O -0.5157 33.0101 0.0 0
M  V30 56 C -2.0631 33.1068 0.0 0 CFG=1
M  V30 57 C -1.4506 34.4608 0.0 0
M  V30 58 C -1.3216 32.043 0.0 0
M  V30 59 C -0.0967 34.5575 0.0 0
M  V30 60 C -2.2565 35.8147 0.0 0
M  V30 61 C -2.4177 31.1404 0.0 0
M  V30 62 C -3.8039 35.9114 0.0 0
M  V30 63 C -3.9006 31.624 0.0 0
M  V30 64 C -4.6098 34.7509 0.0 0 CFG=2
M  V30 65 C -4.9966 30.7213 0.0 0
M  V30 66 C -4.5775 33.3325 0.0 0 CFG=2
M  V30 67 C -6.1571 34.8476 0.0 0
M  V30 68 C -6.1249 33.4292 0.0 0
M  V30 69 C -7.7045 34.9443 0.0 0
M  V30 70 C -6.963 36.2015 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=3
M  V30 5 1 5 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 13 11 CFG=3
M  V30 13 2 12 14
M  V30 14 1 15 12 CFG=1
M  V30 15 1 13 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 2 20 21
M  V30 20 1 21 22
M  V30 21 1 21 23
M  V30 22 1 24 22 CFG=1
M  V30 23 1 24 25
M  V30 24 1 24 26
M  V30 25 2 25 27
M  V30 26 1 25 28
M  V30 27 1 26 29
M  V30 28 1 28 30
M  V30 29 1 29 31
M  V30 30 1 32 30 CFG=3
M  V30 31 2 31 33
M  V30 32 1 34 31 CFG=1
M  V30 33 1 32 35
M  V30 34 1 34 36
M  V30 35 1 35 37
M  V30 36 1 35 38
M  V30 37 1 40 39 CFG=3
M  V30 38 1 40 41
M  V30 39 1 40 42
M  V30 40 2 41 43
M  V30 41 1 41 44
M  V30 42 1 42 45
M  V30 43 1 44 46
M  V30 44 1 45 47
M  V30 45 1 48 46 CFG=3
M  V30 46 2 47 49
M  V30 47 1 50 47 CFG=1
M  V30 48 1 48 51
M  V30 49 1 50 52
M  V30 50 1 51 53
M  V30 51 1 51 54
M  V30 52 1 56 55 CFG=1
M  V30 53 1 56 57
M  V30 54 1 56 58
M  V30 55 2 57 59
M  V30 56 1 57 60
M  V30 57 1 58 61
M  V30 58 1 60 62
M  V30 59 1 61 63
M  V30 60 1 64 62 CFG=3
M  V30 61 2 63 65
M  V30 62 1 66 63 CFG=1
M  V30 63 1 64 67
M  V30 64 1 66 68
M  V30 65 1 67 69
M  V30 66 1 67 70
M  V30 67 1 13 15
M  V30 68 1 16 17
M  V30 69 1 32 34
M  V30 70 1 35 36
M  V30 71 1 48 50
M  V30 72 1 51 52
M  V30 73 1 64 66
M  V30 74 1 67 68
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(12 5 13 15 24 32 34 40 48 50 56 64 66)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00075001.cdx

>  <name>
US20220000157A1-20220106-C00049

>  <Row No>
380

$$$$
US20220000157A1-20220106-C00050
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 70 74 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.5525 0.0862 0.0 0 CFG=2
M  V30 3 C 0.6325 1.3512 0.0 0
M  V30 4 C -2.3575 -1.0925 0.0 0 CFG=2
M  V30 5 C -2.3575 1.4375 0.0 0
M  V30 6 C -0.92 1.4375 0.0 0
M  V30 7 O -0.9775 -1.0062 0.0 0
M  V30 8 C -1.5812 -2.185 0.0 0
M  V30 9 C -3.91 1.5237 0.0 0
M  V30 10 C -2.7025 -3.1338 0.0 0
M  V30 11 C -4.7151 0.345 0.0 0 CFG=1
M  V30 12 C -4.1975 -2.6738 0.0 0
M  V30 13 C -6.2676 0.4312 0.0 0
M  V30 14 C -4.8013 -1.035 0.0 0 CFG=1
M  V30 15 C -5.3188 -3.6225 0.0 0
M  V30 16 C -6.3538 -0.9487 0.0 0
M  V30 17 C -7.8201 0.5175 0.0 0
M  V30 18 C -7.0726 1.7825 0.0 0
M  V30 19 O -0.69 10.3502 0.0 0
M  V30 20 C -2.2425 10.4364 0.0 0 CFG=1
M  V30 21 C -0.0575 11.7015 0.0 0
M  V30 22 C -3.0475 9.2577 0.0 0 CFG=2
M  V30 23 C -3.0475 11.7877 0.0 0
M  V30 24 C -1.61 11.7877 0.0 0
M  V30 25 O -1.6675 9.3439 0.0 0
M  V30 26 C -2.2713 8.1651 0.0 0
M  V30 27 C -4.6001 11.874 0.0 0
M  V30 28 C -3.3925 7.2164 0.0 0
M  V30 29 C -5.4051 10.6952 0.0 0 CFG=1
M  V30 30 C -4.8876 7.6764 0.0 0
M  V30 31 C -6.9576 10.7814 0.0 0
M  V30 32 C -5.4913 9.3152 0.0 0 CFG=1
M  V30 33 C -6.0088 6.7276 0.0 0
M  V30 34 C -7.0439 9.4014 0.0 0
M  V30 35 C -8.5101 10.8677 0.0 0
M  V30 36 C -7.7626 12.1327 0.0 0
M  V30 37 O -0.46 19.7804 0.0 0
M  V30 38 C -2.0125 19.8666 0.0 0 CFG=2
M  V30 39 C -2.8175 18.6879 0.0 0 CFG=2
M  V30 40 C -2.8175 21.2179 0.0 0
M  V30 41 C -1.38 21.2179 0.0 0
M  V30 42 O -1.4375 18.7741 0.0 0
M  V30 43 C -2.0412 17.5953 0.0 0
M  V30 44 C -4.37 21.3042 0.0 0
M  V30 45 C -3.1625 16.6466 0.0 0
M  V30 46 C -5.1751 20.1254 0.0 0 CFG=1
M  V30 47 C -4.6576 17.1066 0.0 0
M  V30 48 C -6.7276 20.2117 0.0 0
M  V30 49 C -5.2613 18.7454 0.0 0 CFG=1
M  V30 50 C -5.7788 16.1578 0.0 0
M  V30 51 C -6.8139 18.8316 0.0 0
M  V30 52 C -8.2801 20.2979 0.0 0
M  V30 53 C -7.5326 21.5629 0.0 0
M  V30 54 O -0.46 29.4406 0.0 0
M  V30 55 C -2.0125 29.5269 0.0 0 CFG=1
M  V30 56 C -2.8175 28.3481 0.0 0 CFG=2
M  V30 57 C -2.8175 30.8781 0.0 0
M  V30 58 C -1.38 30.8781 0.0 0
M  V30 59 O -1.4375 28.4343 0.0 0
M  V30 60 C -2.0412 27.2556 0.0 0
M  V30 61 C -4.37 30.9644 0.0 0
M  V30 62 C -3.1625 26.3068 0.0 0
M  V30 63 C -5.1751 29.7856 0.0 0 CFG=1
M  V30 64 C -4.6576 26.7668 0.0 0
M  V30 65 C -6.7276 29.8719 0.0 0
M  V30 66 C -5.2613 28.4056 0.0 0 CFG=1
M  V30 67 C -5.7788 25.818 0.0 0
M  V30 68 C -6.8139 28.4918 0.0 0
M  V30 69 C -8.2801 29.9581 0.0 0
M  V30 70 C -7.5326 31.2232 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 2 6 CFG=1
M  V30 6 1 4 7 CFG=1
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 8 10
M  V30 10 1 11 9 CFG=3
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 13 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 1 19 20
M  V30 19 1 19 21
M  V30 20 1 20 22
M  V30 21 1 20 23
M  V30 22 1 20 24 CFG=3
M  V30 23 1 22 25 CFG=1
M  V30 24 1 22 26
M  V30 25 1 23 27
M  V30 26 1 26 28
M  V30 27 1 29 27 CFG=3
M  V30 28 1 28 30
M  V30 29 1 29 31
M  V30 30 1 29 32
M  V30 31 2 30 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 31 36
M  V30 35 1 38 37 CFG=3
M  V30 36 1 38 39
M  V30 37 1 38 40
M  V30 38 1 38 41
M  V30 39 1 39 42 CFG=1
M  V30 40 1 39 43
M  V30 41 1 40 44
M  V30 42 1 43 45
M  V30 43 1 46 44 CFG=3
M  V30 44 1 45 47
M  V30 45 1 46 48
M  V30 46 1 46 49
M  V30 47 2 47 50
M  V30 48 1 48 51
M  V30 49 1 48 52
M  V30 50 1 48 53
M  V30 51 1 55 54 CFG=1
M  V30 52 1 55 56
M  V30 53 1 55 57
M  V30 54 1 55 58
M  V30 55 1 56 59 CFG=1
M  V30 56 1 56 60
M  V30 57 1 57 61
M  V30 58 1 60 62
M  V30 59 1 63 61 CFG=3
M  V30 60 1 62 64
M  V30 61 1 63 65
M  V30 62 1 63 66
M  V30 63 2 64 67
M  V30 64 1 65 68
M  V30 65 1 65 69
M  V30 66 1 65 70
M  V30 67 1 14 12 CFG=1
M  V30 68 1 14 16
M  V30 69 1 32 30 CFG=1
M  V30 70 1 32 34
M  V30 71 1 49 47 CFG=1
M  V30 72 1 49 51
M  V30 73 1 66 64 CFG=1
M  V30 74 1 66 68
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(16 2 4 11 14 20 22 29 32 38 39 46 49 55 56 63 66)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00077001.cdx

>  <name>
US20220000157A1-20220106-C00050

>  <Row No>
381

$$$$
US20220000157A1-20220106-C00051
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 17 19 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3087 0.7546 0.0 0 CFG=2
M  V30 3 C -1.3441 2.2638 0.0 0 CFG=2
M  V30 4 C -2.6175 0.0471 0.0 0
M  V30 5 C -2.6529 1.5446 0.0 0
M  V30 6 C -1.3795 3.773 0.0 0
M  V30 7 C 0.0471 2.6883 0.0 0
M  V30 8 C -3.9263 0.8135 0.0 0
M  V30 9 C -3.9617 2.2992 0.0 0 CFG=2
M  V30 10 C -2.6883 4.5394 0.0 0
M  V30 11 C -3.9971 3.8084 0.0 0 CFG=2
M  V30 12 C -5.4002 1.8747 0.0 0 CFG=2
M  V30 13 C -5.4356 4.3036 0.0 0
M  V30 14 O -5.8247 0.4834 0.0 0
M  V30 15 C -6.2963 3.101 0.0 0
M  V30 16 C -6.5085 5.3766 0.0 0
M  V30 17 C -5.0818 5.7657 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=1
M  V30 2 1 3 2 CFG=3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 11 13
M  V30 13 1 12 14 CFG=3
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 13 17
M  V30 17 1 9 8 CFG=3
M  V30 18 1 11 10 CFG=1
M  V30 19 1 13 15
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(5 2 3 9 11 12)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00097001.cdx

>  <name>
US20220000157A1-20220106-C00051

>  <Row No>
382

$$$$
US20220000157A1-20220106-C00052
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3335 0.7688 0.0 0
M  V30 3 O -1.3695 2.3066 0.0 0
M  V30 4 C -2.667 0.036 0.0 0
M  V30 5 C -1.0091 3.7963 0.0 0 CFG=1
M  V30 6 C 0.3844 4.3009 0.0 0 CFG=1
M  V30 7 C -1.9221 5.0457 0.0 0
M  V30 8 C 0.3483 5.8386 0.0 0 CFG=1
M  V30 9 C 1.6458 3.58 0.0 0
M  V30 10 C 0.3483 2.8352 0.0 0
M  V30 11 C -1.0812 6.2952 0.0 0
M  V30 12 C 1.6098 6.6195 0.0 0
M  V30 13 C 2.9073 4.3609 0.0 0 CFG=2
M  V30 14 C 1.6098 2.1144 0.0 0
M  V30 15 C -2.1744 7.3884 0.0 0
M  V30 16 C -0.7208 7.7849 0.0 0
M  V30 17 C 2.8712 5.8987 0.0 0
M  V30 18 C 2.8712 2.8953 0.0 0 CFG=2
M  V30 19 C 4.3249 4.7934 0.0 0
M  V30 20 O 4.1327 2.1744 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=3
M  V30 5 1 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 1 6 10 CFG=3
M  V30 10 1 7 11
M  V30 11 1 8 12 CFG=1
M  V30 12 1 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 1 13 18 CFG=3
M  V30 18 1 13 19
M  V30 19 1 18 20 CFG=1
M  V30 20 1 8 11
M  V30 21 1 13 17
M  V30 22 1 14 18
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(5 5 6 8 13 18)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00098001.cdx

>  <name>
US20220000157A1-20220106-C00052

>  <Row No>
383

$$$$
US20220000157A1-20220106-C00053
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0356 -1.4491 0.0 0
M  V30 3 O -1.3541 -2.1619 0.0 0
M  V30 4 C 1.2116 -2.1619 0.0 0
M  V30 5 C -2.6726 -1.3897 0.0 0 CFG=2
M  V30 6 C -2.7083 0.1306 0.0 0 CFG=2
M  V30 7 C -3.9912 -2.1025 0.0 0
M  V30 8 C -4.0268 -0.582 0.0 0
M  V30 9 C -2.7439 1.6511 0.0 0
M  V30 10 C -1.3066 0.5582 0.0 0
M  V30 11 C -5.3097 -1.3304 0.0 0
M  V30 12 C -5.3453 0.1781 0.0 0 CFG=2
M  V30 13 C -4.0624 2.4232 0.0 0
M  V30 14 C -5.381 1.6986 0.0 0 CFG=2
M  V30 15 C -6.7945 -0.2494 0.0 0 CFG=2
M  V30 16 C -6.8302 2.1975 0.0 0
M  V30 17 O -7.2222 -1.6511 0.0 0
M  V30 18 C -7.6973 0.9859 0.0 0
M  V30 19 C -7.9111 3.2784 0.0 0
M  V30 20 C -6.4738 3.6704 0.0 0
M  V30 21 C -7.2578 -3.1003 0.0 0
M  V30 22 O -6.0105 -3.8249 0.0 0
M  V30 23 C -8.5763 -3.8249 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=1
M  V30 5 1 6 5 CFG=3
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 12 14
M  V30 14 1 12 15
M  V30 15 1 14 16
M  V30 16 1 15 17 CFG=3
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 2 21 22
M  V30 22 1 21 23
M  V30 23 1 12 11 CFG=3
M  V30 24 1 14 13 CFG=1
M  V30 25 1 16 18
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(5 5 6 12 14 15)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00099001.cdx

>  <name>
US20220000157A1-20220106-C00053

>  <Row No>
384

$$$$
US20220000157A1-20220106-C00054
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3298 0.7667 0.0 0
M  V30 3 O -1.3657 2.3002 0.0 0
M  V30 4 C -2.6596 0.0359 0.0 0
M  V30 5 C -1.0063 3.7857 0.0 0 CFG=1
M  V30 6 C -3.9894 0.8146 0.0 0
M  V30 7 C 0.3833 4.2889 0.0 0 CFG=1
M  V30 8 C -1.9168 5.0317 0.0 0
M  V30 9 C -5.3192 0.0838 0.0 0
M  V30 10 C -4.0253 2.3481 0.0 0
M  V30 11 C 0.3474 5.8224 0.0 0 CFG=1
M  V30 12 C 1.6413 3.5701 0.0 0
M  V30 13 C 0.3474 2.8273 0.0 0
M  V30 14 C -1.0782 6.2776 0.0 0
M  V30 15 C 1.6053 6.6011 0.0 0
M  V30 16 C 2.8992 4.3368 0.0 0 CFG=2
M  V30 17 C 1.6053 2.1085 0.0 0
M  V30 18 C -2.1684 7.3679 0.0 0
M  V30 19 C -0.7188 7.7632 0.0 0
M  V30 20 C 2.8632 5.8823 0.0 0
M  V30 21 C 2.8632 2.8752 0.0 0 CFG=2
M  V30 22 C 4.3129 4.7681 0.0 0
M  V30 23 O 4.1212 2.1564 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=3
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 1 7 13 CFG=3
M  V30 13 1 8 14
M  V30 14 1 11 15 CFG=1
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 1 14 19
M  V30 19 1 15 20
M  V30 20 1 16 21 CFG=3
M  V30 21 1 16 22
M  V30 22 1 21 23 CFG=1
M  V30 23 1 11 14
M  V30 24 1 16 20
M  V30 25 1 17 21
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(5 5 7 11 16 21)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00100001.cdx

>  <name>
US20220000157A1-20220106-C00054

>  <Row No>
385

$$$$
US20220000157A1-20220106-C00055
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 17 19 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3087 0.7546 0.0 0 CFG=2
M  V30 3 C -1.3441 2.2638 0.0 0 CFG=2
M  V30 4 C -2.6175 0.0471 0.0 0
M  V30 5 C -2.6529 1.5446 0.0 0
M  V30 6 C -1.3795 3.773 0.0 0
M  V30 7 C 0.0471 2.6883 0.0 0
M  V30 8 C -3.9263 0.8135 0.0 0
M  V30 9 C -3.9617 2.2992 0.0 0 CFG=2
M  V30 10 C -2.6883 4.5394 0.0 0
M  V30 11 C -3.9971 3.8084 0.0 0 CFG=2
M  V30 12 C -5.4002 1.8747 0.0 0 CFG=1
M  V30 13 C -5.4356 4.3036 0.0 0
M  V30 14 C -6.2963 3.101 0.0 0
M  V30 15 C -5.8247 0.4834 0.0 0
M  V30 16 C -6.5085 5.3766 0.0 0
M  V30 17 C -5.0818 5.7657 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=1
M  V30 2 1 3 2 CFG=3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 12 15 CFG=3
M  V30 15 1 13 16
M  V30 16 1 13 17
M  V30 17 1 9 8 CFG=3
M  V30 18 1 11 10 CFG=1
M  V30 19 1 13 14
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(5 2 3 9 11 12)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00101001.cdx

>  <name>
US20220000157A1-20220106-C00055

>  <Row No>
386

$$$$
US20220000157A1-20220106-C00056
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.543 0.0361 0.0 0 CFG=2
M  V30 3 C -0.8197 1.3742 0.0 0
M  V30 4 C -0.9161 -0.9041 0.0 0
M  V30 5 C -1.5912 2.7124 0.0 0
M  V30 6 C 0.6509 1.4104 0.0 0
M  V30 7 C -2.0132 -1.9288 0.0 0
M  V30 8 C -3.1343 2.7485 0.0 0
M  V30 9 C -3.508 -1.4948 0.0 0
M  V30 10 C -3.9058 1.4827 0.0 0 CFG=1
M  V30 11 C -4.605 -2.5195 0.0 0
M  V30 12 C -3.942 0.0 0.0 0 CFG=1
M  V30 13 C -5.4489 1.5189 0.0 0
M  V30 14 C -5.485 0.0361 0.0 0
M  V30 15 C -6.5459 2.6159 0.0 0
M  V30 16 C -6.9919 1.5551 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=3
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 10 8 CFG=1
M  V30 10 2 9 11
M  V30 11 1 12 9 CFG=3
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 10 12
M  V30 17 1 13 14
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 2 10 12)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00102001.cdx

>  <name>
US20220000157A1-20220106-C00056

>  <Row No>
387

$$$$
US20220000157A1-20220106-C00057
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 17 18 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.5484 0.0362 0.0 0 CFG=2
M  V30 3 C -2.3348 -1.2339 0.0 0 CFG=1
M  V30 4 C -2.3348 1.3791 0.0 0
M  V30 5 C -0.8105 1.3791 0.0 0
M  V30 6 O -0.8589 -1.1976 0.0 0
M  V30 7 C -1.7057 -2.1775 0.0 0
M  V30 8 C -3.8833 1.4154 0.0 0
M  V30 9 C -2.8066 -3.2058 0.0 0
M  V30 10 C -4.6575 0.1451 0.0 0 CFG=2
M  V30 11 C -4.3067 -2.7703 0.0 0
M  V30 12 C -6.206 0.1814 0.0 0
M  V30 13 C -4.6938 -1.3307 0.0 0 CFG=2
M  V30 14 C -5.4075 -3.7986 0.0 0
M  V30 15 C -6.2423 -1.2944 0.0 0
M  V30 16 C -7.3068 1.2823 0.0 0
M  V30 17 C -7.7545 0.2177 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5 CFG=1
M  V30 5 1 3 6 CFG=3
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 7 9
M  V30 9 1 10 8 CFG=1
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 2 11 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 1 12 17
M  V30 17 1 13 11 CFG=3
M  V30 18 1 13 15
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(4 2 3 10 13)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00103001.cdx

>  <name>
US20220000157A1-20220106-C00057

>  <Row No>
388

$$$$
US20220000157A1-20220106-C00058
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.543 0.0361 0.0 0 CFG=2
M  V30 3 C -0.8197 1.3742 0.0 0
M  V30 4 C -0.9161 -0.9041 0.0 0
M  V30 5 C 0.6509 1.4104 0.0 0
M  V30 6 C -1.5912 2.7124 0.0 0
M  V30 7 C -2.0132 -1.9288 0.0 0
M  V30 8 C -3.1343 2.7485 0.0 0
M  V30 9 C -3.508 -1.4948 0.0 0
M  V30 10 C -3.9058 1.4827 0.0 0 CFG=1
M  V30 11 C -4.605 -2.5195 0.0 0
M  V30 12 C -3.942 0.0 0.0 0 CFG=1
M  V30 13 C -5.4489 1.5189 0.0 0
M  V30 14 C -5.485 0.0361 0.0 0
M  V30 15 C -6.5459 2.6159 0.0 0
M  V30 16 C -6.9919 1.5551 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=3
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 10 8 CFG=1
M  V30 10 2 9 11
M  V30 11 1 12 9 CFG=3
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 10 12
M  V30 17 1 13 14
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 2 10 12)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00104001.cdx

>  <name>
US20220000157A1-20220106-C00058

>  <Row No>
389

$$$$
US20220000157A1-20220106-C00059
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 19 20 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.5388 0.036 0.0 0
M  V30 3 O -2.3202 1.3704 0.0 0
M  V30 4 C -2.3202 -1.2262 0.0 0
M  V30 5 C -3.859 1.4065 0.0 0 CFG=2
M  V30 6 C -3.1377 2.7409 0.0 0
M  V30 7 C -3.2338 0.4688 0.0 0
M  V30 8 C -1.671 2.777 0.0 0
M  V30 9 C -3.9071 4.0754 0.0 0
M  V30 10 C -4.3278 -0.553 0.0 0
M  V30 11 C -5.4459 4.1114 0.0 0
M  V30 12 C -5.8186 -0.1202 0.0 0
M  V30 13 C -6.2153 2.8491 0.0 0 CFG=1
M  V30 14 C -6.9126 -1.142 0.0 0
M  V30 15 C -6.2513 1.3704 0.0 0 CFG=1
M  V30 16 C -7.7541 2.8852 0.0 0
M  V30 17 C -7.7902 1.4065 0.0 0
M  V30 18 C -8.8481 3.9792 0.0 0
M  V30 19 C -9.2929 2.9213 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=3
M  V30 5 1 5 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 13 11 CFG=1
M  V30 13 2 12 14
M  V30 14 1 15 12 CFG=3
M  V30 15 1 13 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 1 13 15
M  V30 20 1 16 17
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 5 13 15)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00105001.cdx

>  <name>
US20220000157A1-20220106-C00059

>  <Row No>
390

$$$$
US20220000157A1-20220106-C00060
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 19 20 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.5388 0.036 0.0 0
M  V30 3 O -2.3202 1.3704 0.0 0
M  V30 4 C -2.3202 -1.2262 0.0 0
M  V30 5 C -3.859 1.4065 0.0 0 CFG=2
M  V30 6 C -3.1377 2.7409 0.0 0
M  V30 7 C -3.2338 0.4688 0.0 0
M  V30 8 C -3.9071 4.0754 0.0 0
M  V30 9 C -1.671 2.777 0.0 0
M  V30 10 C -4.3278 -0.553 0.0 0
M  V30 11 C -5.4459 4.1114 0.0 0
M  V30 12 C -5.8186 -0.1202 0.0 0
M  V30 13 C -6.2153 2.8491 0.0 0 CFG=1
M  V30 14 C -6.9126 -1.142 0.0 0
M  V30 15 C -6.2513 1.3704 0.0 0 CFG=1
M  V30 16 C -7.7541 2.8852 0.0 0
M  V30 17 C -7.7902 1.4065 0.0 0
M  V30 18 C -8.8481 3.9792 0.0 0
M  V30 19 C -9.2929 2.9213 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=3
M  V30 5 1 5 6
M  V30 6 1 5 7
M  V30 7 2 6 8 CFG=2
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 10 12
M  V30 12 1 13 11 CFG=1
M  V30 13 2 12 14
M  V30 14 1 15 12 CFG=3
M  V30 15 1 13 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 1 13 15
M  V30 20 1 16 17
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 5 13 15)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00106001.cdx

>  <name>
US20220000157A1-20220106-C00060

>  <Row No>
391

$$$$
US20220000157A1-20220106-C00061
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00122001.cdx

>  <name>
US20220000157A1-20220106-C00061

>  <Row No>
392

$$$$
US20220000157A1-20220106-C00062
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=4
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00123001.cdx

>  <name>
US20220000157A1-20220106-C00062

>  <Row No>
393

$$$$
US20220000157A1-20220106-C00063
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=5
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00124001.cdx

>  <name>
US20220000157A1-20220106-C00063

>  <Row No>
394

$$$$
US20220000157A1-20220106-C00064
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=6
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00125001.cdx

>  <name>
US20220000157A1-20220106-C00064

>  <Row No>
395

$$$$
US20220000157A1-20220106-C00065
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=8
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00126001.cdx

>  <name>
US20220000157A1-20220106-C00065

>  <Row No>
396

$$$$
US20220000157A1-20220106-C00066
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00127001.cdx

>  <name>
US20220000157A1-20220106-C00066

>  <Row No>
397

$$$$
US20220000157A1-20220106-C00067
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=4
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00128001.cdx

>  <name>
US20220000157A1-20220106-C00067

>  <Row No>
398

$$$$
US20220000157A1-20220106-C00068
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=5
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00129001.cdx

>  <name>
US20220000157A1-20220106-C00068

>  <Row No>
399

$$$$
US20220000157A1-20220106-C00069
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=6
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00130001.cdx

>  <name>
US20220000157A1-20220106-C00069

>  <Row No>
400

$$$$
US20220000157A1-20220106-C00070
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=8
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00131001.cdx

>  <name>
US20220000157A1-20220106-C00070

>  <Row No>
401

$$$$
US20220000157A1-20220106-C00071
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00132001.cdx

>  <name>
US20220000157A1-20220106-C00071

>  <Row No>
402

$$$$
US20220000157A1-20220106-C00072
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=4
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00133001.cdx

>  <name>
US20220000157A1-20220106-C00072

>  <Row No>
403

$$$$
US20220000157A1-20220106-C00073
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=5
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00134001.cdx

>  <name>
US20220000157A1-20220106-C00073

>  <Row No>
404

$$$$
US20220000157A1-20220106-C00074
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=6
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00135001.cdx

>  <name>
US20220000157A1-20220106-C00074

>  <Row No>
405

$$$$
US20220000157A1-20220106-C00075
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=8
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00136001.cdx

>  <name>
US20220000157A1-20220106-C00075

>  <Row No>
406

$$$$
US20220000157A1-20220106-C00076
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00137001.cdx

>  <name>
US20220000157A1-20220106-C00076

>  <Row No>
407

$$$$
US20220000157A1-20220106-C00077
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=4
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00138001.cdx

>  <name>
US20220000157A1-20220106-C00077

>  <Row No>
408

$$$$
US20220000157A1-20220106-C00078
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=5
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00139001.cdx

>  <name>
US20220000157A1-20220106-C00078

>  <Row No>
409

$$$$
US20220000157A1-20220106-C00079
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=6
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00140001.cdx

>  <name>
US20220000157A1-20220106-C00079

>  <Row No>
410

$$$$
US20220000157A1-20220106-C00080
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=8
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00141001.cdx

>  <name>
US20220000157A1-20220106-C00080

>  <Row No>
411

$$$$
US20220000157A1-20220106-C00081
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00142001.cdx

>  <name>
US20220000157A1-20220106-C00081

>  <Row No>
412

$$$$
US20220000157A1-20220106-C00082
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
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>  <Molecule Name>
00143001.cdx

>  <name>
US20220000157A1-20220106-C00082

>  <Row No>
413

$$$$
US20220000157A1-20220106-C00083
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=4
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00144001.cdx

>  <name>
US20220000157A1-20220106-C00083

>  <Row No>
414

$$$$
US20220000157A1-20220106-C00084
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=5
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00145001.cdx

>  <name>
US20220000157A1-20220106-C00084

>  <Row No>
415

$$$$
US20220000157A1-20220106-C00085
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=6
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00146001.cdx

>  <name>
US20220000157A1-20220106-C00085

>  <Row No>
416

$$$$
US20220000157A1-20220106-C00086
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=8
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00147001.cdx

>  <name>
US20220000157A1-20220106-C00086

>  <Row No>
417

$$$$
US20220000157A1-20220106-C00087
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00148001.cdx

>  <name>
US20220000157A1-20220106-C00087

>  <Row No>
418

$$$$
US20220000157A1-20220106-C00088
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=4
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00149001.cdx

>  <name>
US20220000157A1-20220106-C00088

>  <Row No>
419

$$$$
US20220000157A1-20220106-C00089
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=5
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00150001.cdx

>  <name>
US20220000157A1-20220106-C00089

>  <Row No>
420

$$$$
US20220000157A1-20220106-C00090
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=6
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00151001.cdx

>  <name>
US20220000157A1-20220106-C00090

>  <Row No>
421

$$$$
US20220000157A1-20220106-C00091
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=8
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00152001.cdx

>  <name>
US20220000157A1-20220106-C00091

>  <Row No>
422

$$$$
US20220000164A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 4 3 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0352 -1.4801 0.0 0
M  V30 3 O 1.2452 -2.2202 0.0 0
M  V30 4 ? -1.3862 -2.2202 0.0 0 MASS=22
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000164A1-20220106-C00001

>  <Row No>
423

$$$$
US20220000164A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 32 35 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0361 -1.4714 0.0 0
M  V30 3 O 1.2302 -2.2071 0.0 0
M  V30 4 ? -1.3749 -2.2071 0.0 0 MASS=21
M  V30 5 C 2.4965 -1.4231 0.0 0 CFG=1
M  V30 6 C 3.7629 -2.1588 0.0 0
M  V30 7 C 2.4604 0.1206 0.0 0
M  V30 8 C 5.0293 -1.3749 0.0 0
M  V30 9 C 3.7268 0.9045 0.0 0
M  V30 10 C 6.2957 -2.1106 0.0 0
M  V30 11 C 4.9931 0.1688 0.0 0 CFG=1
M  V30 12 C 7.5621 -1.3266 0.0 0
M  V30 13 C 6.2595 0.9528 0.0 0 CFG=1
M  V30 14 C 4.957 1.7126 0.0 0
M  V30 15 C 7.5259 0.217 0.0 0 CFG=1
M  V30 16 C 6.2233 2.4965 0.0 0
M  V30 17 C 8.7923 1.001 0.0 0 CFG=2
M  V30 18 C 7.4897 3.2805 0.0 0
M  V30 19 C 8.7561 2.5448 0.0 0 CFG=1
M  V30 20 C 10.0587 0.2653 0.0 0
M  V30 21 C 10.0225 3.3287 0.0 0
M  V30 22 C 8.7199 4.0886 0.0 0
M  V30 23 C 11.3251 1.0492 0.0 0
M  V30 24 C 11.2889 2.593 0.0 0 CFG=1
M  V30 25 C 12.3141 3.6906 0.0 0 CFG=2
M  V30 26 C 13.7373 3.3287 0.0 0
M  V30 27 C 11.8799 5.1861 0.0 0
M  V30 28 C 14.7624 4.4263 0.0 0
M  V30 29 C 16.1856 4.0645 0.0 0
M  V30 30 C 17.2108 5.162 0.0 0
M  V30 31 C 16.7766 6.6575 0.0 0
M  V30 32 C 18.634 4.8002 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=3
M  V30 5 1 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 11 14 CFG=3
M  V30 14 1 15 12 CFG=1
M  V30 15 1 13 16 CFG=3
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 17 20 CFG=3
M  V30 20 1 19 21
M  V30 21 1 19 22 CFG=3
M  V30 22 1 20 23
M  V30 23 1 24 21 CFG=3
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 26 1 25 27 CFG=1
M  V30 27 1 26 28
M  V30 28 1 28 29
M  V30 29 1 29 30
M  V30 30 1 30 31
M  V30 31 1 30 32
M  V30 32 1 9 11
M  V30 33 1 13 15
M  V30 34 1 18 19
M  V30 35 1 23 24
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(8 5 11 13 15 17 19 24 25)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000164A1-20220106-C00003

>  <Row No>
424

$$$$
US20220000167A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 36 39 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0 CHG=1
M  V30 2 C 1.2592 0.7795 0.0 0
M  V30 3 C -1.3311 0.7795 0.0 0
M  V30 4 C 1.2232 2.3145 0.0 0
M  V30 5 C -1.3671 2.3145 0.0 0
M  V30 6 C -0.1079 3.094 0.0 0
M  V30 7 C 2.4824 3.094 0.0 0 CFG=1
M  V30 8 N 3.8136 2.5064 0.0 0 CHG=1
M  V30 9 C 2.6023 4.617 0.0 0
M  V30 10 C 4.7729 3.6457 0.0 0
M  V30 11 C 4.8329 1.487 0.0 0
M  V30 12 C 4.0294 4.9648 0.0 0
M  V30 13 N 3.4538 8.2508 0.0 0
M  V30 14 C 4.713 9.0303 0.0 0
M  V30 15 C 2.1226 9.0303 0.0 0
M  V30 16 C 4.677 10.5653 0.0 0
M  V30 17 C 2.0866 10.5653 0.0 0
M  V30 18 C 3.3458 11.3448 0.0 0
M  V30 19 C 5.9362 11.3448 0.0 0 CFG=1
M  V30 20 N 7.2674 10.7572 0.0 0 CHG=1
M  V30 21 C 6.0561 12.8679 0.0 0
M  V30 22 C 8.2268 11.8965 0.0 0
M  V30 23 C 8.2867 9.7378 0.0 0
M  V30 24 C 7.4832 13.2156 0.0 0
M  V30 25 N -4.0294 8.2508 0.0 0
M  V30 26 C -2.7702 9.0303 0.0 0
M  V30 27 C -5.3606 9.0303 0.0 0
M  V30 28 C -2.8062 10.5653 0.0 0
M  V30 29 C -5.3966 10.5653 0.0 0
M  V30 30 C -4.1373 11.3448 0.0 0
M  V30 31 C -1.547 11.3448 0.0 0 CFG=1
M  V30 32 N -0.2158 10.7572 0.0 0
M  V30 33 C -1.4271 12.8679 0.0 0
M  V30 34 C 0.7435 11.8965 0.0 0
M  V30 35 C 0.0599 9.3301 0.0 0
M  V30 36 C 0.0 13.2156 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 2 4 6
M  V30 6 1 7 4 CFG=3
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 2 13 14
M  V30 13 1 13 15
M  V30 14 1 14 16
M  V30 15 2 15 17
M  V30 16 2 16 18
M  V30 17 1 19 16 CFG=3
M  V30 18 1 19 20
M  V30 19 1 19 21
M  V30 20 1 20 22
M  V30 21 1 20 23
M  V30 22 1 21 24
M  V30 23 2 25 26
M  V30 24 1 25 27
M  V30 25 1 26 28
M  V30 26 2 27 29
M  V30 27 2 28 30
M  V30 28 1 31 28 CFG=3
M  V30 29 1 31 32
M  V30 30 1 31 33
M  V30 31 1 32 34
M  V30 32 1 32 35
M  V30 33 1 33 36
M  V30 34 1 5 6
M  V30 35 1 10 12
M  V30 36 1 17 18
M  V30 37 1 22 24
M  V30 38 1 29 30
M  V30 39 1 34 36
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 7 19 31)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000167A1-20220106-C00001

>  <Row No>
425

$$$$
US20220000167A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 13 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C 1.2586 0.7791 0.0 0
M  V30 3 C -1.3306 0.7791 0.0 0
M  V30 4 C 1.2227 2.3136 0.0 0
M  V30 5 C -1.3665 2.3136 0.0 0
M  V30 6 C -0.1078 3.0927 0.0 0
M  V30 7 C 2.4814 3.0927 0.0 0 CFG=1
M  V30 8 N 3.812 2.5054 0.0 0
M  V30 9 C 2.6013 4.6152 0.0 0
M  V30 10 C 4.771 3.6442 0.0 0
M  V30 11 C 4.0877 1.0788 0.0 0
M  V30 12 C 4.0278 4.9628 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 2 4 6
M  V30 6 1 7 4 CFG=3
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 1 5 6
M  V30 13 1 10 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 7)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000167A1-20220106-C00002

>  <Row No>
426

$$$$
US20220000167A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 38 39 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0 CHG=1
M  V30 2 C 1.2525 0.7983 0.0 0
M  V30 3 C -1.335 0.7983 0.0 0
M  V30 4 C 1.2112 2.326 0.0 0
M  V30 5 C -1.3763 2.326 0.0 0
M  V30 6 C -0.1238 3.1244 0.0 0
M  V30 7 C 2.4637 3.1244 0.0 0 CFG=1
M  V30 8 N 3.785 2.5463 0.0 0 CHG=1
M  V30 9 C 2.5876 4.6521 0.0 0
M  V30 10 C 4.7347 3.6887 0.0 0
M  V30 11 C 4.0603 1.1286 0.0 0
M  V30 12 C 4.0052 5.01 0.0 0
M  V30 13 N -3.8538 8.1482 0.0 0
M  V30 14 C -2.6013 8.9465 0.0 0
M  V30 15 C -5.1889 8.9465 0.0 0
M  V30 16 C -2.6426 10.4743 0.0 0
M  V30 17 C -5.2302 10.4743 0.0 0
M  V30 18 C -3.9777 11.2726 0.0 0
M  V30 19 C -1.3901 11.2726 0.0 0 CFG=1
M  V30 20 N -0.0688 10.6945 0.0 0 CHG=1
M  V30 21 C -1.2662 12.8004 0.0 0
M  V30 22 C 0.8808 11.8369 0.0 0
M  V30 23 C 0.2064 9.2768 0.0 0
M  V30 24 C 0.1514 13.1582 0.0 0
M  V30 25 N -14.0942 8.1482 0.0 0
M  V30 26 C -12.8417 8.9465 0.0 0
M  V30 27 C -15.4293 8.9465 0.0 0
M  V30 28 C -12.883 10.4743 0.0 0
M  V30 29 C -15.4706 10.4743 0.0 0
M  V30 30 C -14.218 11.2726 0.0 0
M  V30 31 C -11.6304 11.2726 0.0 0 CFG=1
M  V30 32 N -10.3091 10.6945 0.0 0
M  V30 33 C -11.5066 12.8004 0.0 0
M  V30 34 C -9.3594 11.8369 0.0 0
M  V30 35 C -10.0338 9.2768 0.0 0
M  V30 36 C -10.0889 13.1582 0.0 0
M  V30 37 H 2.8628 10.901 0.0 0 CHG=1
M  V30 38 H -7.3774 10.901 0.0 0 CHG=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 2 4 6
M  V30 6 1 7 4 CFG=3
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 2 13 14
M  V30 13 1 13 15
M  V30 14 1 14 16
M  V30 15 2 15 17
M  V30 16 2 16 18
M  V30 17 1 19 16 CFG=3
M  V30 18 1 19 20
M  V30 19 1 19 21
M  V30 20 1 20 22
M  V30 21 1 20 23
M  V30 22 1 21 24
M  V30 23 2 25 26
M  V30 24 1 25 27
M  V30 25 1 26 28
M  V30 26 2 27 29
M  V30 27 2 28 30
M  V30 28 1 31 28 CFG=3
M  V30 29 1 31 32
M  V30 30 1 31 33
M  V30 31 1 32 34
M  V30 32 1 32 35
M  V30 33 1 33 36
M  V30 34 1 5 6
M  V30 35 1 10 12
M  V30 36 1 17 18
M  V30 37 1 22 24
M  V30 38 1 29 30
M  V30 39 1 34 36
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 7 19 31)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000167A1-20220106-C00003

>  <Row No>
427

$$$$
US20220000401A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 4 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 O 1.4995 0.0357 0.0 0
M  V30 3 O -3.7132 7.8073 0.0 0
M  V30 4 O -2.2136 7.843 0.0 0
M  V30 5 O -5.9983 0.2856 0.0 0
M  V30 6 O -4.4987 0.3213 0.0 0
M  V30 7 O 9.9019 7.8073 0.0 0
M  V30 8 O 11.4015 7.843 0.0 0
M  V30 9 C 2.9515 0.2856 0.0 0
M  V30 10 C 5.8078 0.2856 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 3 4
M  V30 3 1 5 6
M  V30 4 1 7 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000401A1-20220106-C00001

>  <Row No>
428

$$$$
US20220000481A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000481A1-20220106-C00001

>  <Row No>
429

$$$$
US20220000481A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000481A1-20220106-C00002

>  <Row No>
430

$$$$
US20220000481A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 35 34 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.1142 0.7428 0.0 0
M  V30 3 O 1.0487 2.2285 0.0 0
M  V30 4 C 2.2285 0.131 0.0 0
M  V30 5 C 2.163 2.9714 0.0 0
M  V30 6 C 3.3428 0.8739 0.0 0
M  V30 7 C 2.163 -1.1798 0.0 0
M  V30 8 C 2.0974 4.4571 0.0 0
M  V30 9 C 3.2773 2.3596 0.0 0
M  V30 10 O 3.2117 5.2 0.0 0
M  V30 11 C 0.8521 5.2 0.0 0
M  V30 12 C 5.9647 4.1075 0.0 0
M  V30 13 O -0.3932 4.5882 0.0 0
M  V30 14 O 5.8991 2.7966 0.0 0
M  V30 15 C 7.079 4.8504 0.0 0
M  V30 16 C -1.6386 5.3311 0.0 0
M  V30 17 O 8.3899 4.2386 0.0 0
M  V30 18 O -2.884 4.7193 0.0 0
M  V30 19 ? 9.8538 5.0689 0.0 0
M  V30 20 C -4.4134 5.484 0.0 0
M  V30 21 O -4.479 6.9697 0.0 0
M  V30 22 C -5.6588 4.8722 0.0 0
M  V30 23 O -6.9042 5.6151 0.0 0
M  V30 24 C -9.3512 4.61 0.0 0
M  V30 25 C -10.5966 5.3529 0.0 0
M  V30 26 O -11.842 4.7411 0.0 0
M  V30 27 C -10.6622 6.8386 0.0 0
M  V30 28 ? -13.0874 5.484 0.0 0
M  V30 29 O -11.9075 7.5815 0.0 0
M  V30 30 C -9.5479 7.5815 0.0 0
M  V30 31 C -11.9731 9.0672 0.0 0
M  V30 32 O -10.8588 9.8101 0.0 0
M  V30 33 C -13.2185 9.8101 0.0 0
M  V30 34 C -14.4638 9.1983 0.0 0
M  V30 35 C -13.284 11.2958 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 8 10
M  V30 10 1 8 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 2 12 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 2 20 21
M  V30 21 1 20 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 26 1 25 27
M  V30 27 1 26 28
M  V30 28 1 27 29
M  V30 29 1 27 30
M  V30 30 1 29 31
M  V30 31 2 31 32
M  V30 32 1 31 33
M  V30 33 2 33 34
M  V30 34 1 33 35
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000481A1-20220106-C00003

>  <Row No>
431

$$$$
US20220000481A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000481A1-20220106-C00004

>  <Row No>
432

$$$$
US20220000481A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 70 68 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2774 -0.695 0.0 0
M  V30 3 O 2.5923 0.0 0.0 0
M  V30 4 C 0.8829 -2.1227 0.0 0
M  V30 5 C 3.9073 -0.5823 0.0 0
M  V30 6 C 1.747 -3.2311 0.0 0
M  V30 7 C 4.1891 -2.01 0.0 0
M  V30 8 C 3.2123 -3.1747 0.0 0
M  V30 9 O 8.1153 0.4508 0.0 0
M  V30 10 C 8.0589 -1.0144 0.0 0
M  V30 11 O 9.3363 -1.7094 0.0 0
M  V30 12 C 6.6688 -1.7094 0.0 0
M  V30 13 C 10.6138 -0.9017 0.0 0
M  V30 14 C 5.2787 -0.9017 0.0 0
M  V30 15 C 6.6124 -3.1747 0.0 0
M  V30 16 C 11.8912 -1.5967 0.0 0
M  V30 17 O 12.5862 -2.8741 0.0 0
M  V30 18 C 13.3564 -1.5404 0.0 0
M  V30 19 O 11.4215 -18.9357 0.0 0
M  V30 20 C 12.6989 -18.128 0.0 0
M  V30 21 O 12.6426 -16.55 0.0 0
M  V30 22 C 13.9764 -18.823 0.0 0
M  V30 23 C 11.2525 -15.7422 0.0 0
M  V30 24 C 15.2538 -18.0152 0.0 0
M  V30 25 C 13.92 -20.2883 0.0 0
M  V30 26 C 11.1961 -14.1642 0.0 0
M  V30 27 O 9.806 -13.3564 0.0 0
M  V30 28 C 12.4735 -13.3564 0.0 0
M  V30 29 C 8.4159 -14.0515 0.0 0
M  V30 30 O 13.7509 -14.0515 0.0 0
M  V30 31 O 8.3595 -15.5168 0.0 0
M  V30 32 C 7.0257 -13.2437 0.0 0
M  V30 33 C 15.0283 -13.2437 0.0 0
M  V30 34 C 5.6356 -13.9388 0.0 0
M  V30 35 C 16.3058 -13.9388 0.0 0
M  V30 36 C 4.2455 -13.131 0.0 0
M  V30 37 C 17.5832 -13.131 0.0 0
M  V30 38 C 2.8553 -13.8261 0.0 0
M  V30 39 C 18.8606 -13.8261 0.0 0
M  V30 40 C 1.4652 -13.0183 0.0 0
M  V30 41 C 20.138 -13.0183 0.0 0
M  V30 42 O 0.0751 -13.7134 0.0 0
M  V30 43 C 21.4154 -13.7134 0.0 0
M  V30 44 O 22.6928 -12.9056 0.0 0
M  V30 45 C 23.9702 -13.6006 0.0 0
M  V30 46 O 23.9139 -15.0659 0.0 0
M  V30 47 C 25.2477 -12.7929 0.0 0
M  V30 48 C 26.5251 -13.4879 0.0 0
M  V30 49 C 27.8025 -12.6802 0.0 0
M  V30 50 C 29.0799 -13.3752 0.0 0
M  V30 51 C 30.3573 -12.5674 0.0 0
M  V30 52 O 31.6347 -13.2625 0.0 0
M  V30 53 C 32.9121 -12.4547 0.0 0
M  V30 54 C 34.1896 -13.1498 0.0 0
M  V30 55 O 35.467 -12.342 0.0 0
M  V30 56 C 34.1332 -14.6151 0.0 0
M  V30 57 O 32.7431 -15.3101 0.0 0
M  V30 58 C 32.6867 -16.7754 0.0 0
M  V30 59 O 31.2966 -17.4705 0.0 0
M  V30 60 C 33.9641 -17.4705 0.0 0
M  V30 61 C 35.2415 -16.6627 0.0 0
M  V30 62 C 33.9078 -18.9357 0.0 0
M  V30 63 O 15.1786 -0.7514 0.0 0
M  V30 64 C 16.456 -1.4464 0.0 0
M  V30 65 C 17.7335 -0.6387 0.0 0
M  V30 66 C 19.0109 -1.3337 0.0 0
M  V30 67 C 20.2883 -0.5259 0.0 0
M  V30 68 C 21.5657 -1.221 0.0 0
M  V30 69 C 22.8431 -0.4132 0.0 0
M  V30 70 O 24.1205 -1.1083 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 9 10
M  V30 9 1 10 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 2 12 14
M  V30 13 1 12 15
M  V30 14 1 13 16
M  V30 15 1 16 17
M  V30 16 1 16 18
M  V30 17 2 19 20
M  V30 18 1 20 21
M  V30 19 1 20 22
M  V30 20 1 21 23
M  V30 21 2 22 24
M  V30 22 1 22 25
M  V30 23 1 23 26
M  V30 24 1 26 27
M  V30 25 1 26 28
M  V30 26 1 27 29
M  V30 27 1 28 30
M  V30 28 2 29 31
M  V30 29 1 29 32
M  V30 30 1 30 33
M  V30 31 1 32 34
M  V30 32 1 33 35
M  V30 33 1 34 36
M  V30 34 1 35 37
M  V30 35 1 36 38
M  V30 36 1 37 39
M  V30 37 1 38 40
M  V30 38 1 39 41
M  V30 39 1 40 42
M  V30 40 1 41 43
M  V30 41 1 43 44
M  V30 42 1 44 45
M  V30 43 2 45 46
M  V30 44 1 45 47
M  V30 45 1 47 48
M  V30 46 1 48 49
M  V30 47 1 49 50
M  V30 48 1 50 51
M  V30 49 1 51 52
M  V30 50 1 52 53
M  V30 51 1 53 54
M  V30 52 1 54 55
M  V30 53 1 54 56
M  V30 54 1 56 57
M  V30 55 1 57 58
M  V30 56 2 58 59
M  V30 57 1 58 60
M  V30 58 2 60 61
M  V30 59 1 60 62
M  V30 60 1 63 64
M  V30 61 1 64 65
M  V30 62 1 65 66
M  V30 63 1 66 67
M  V30 64 1 67 68
M  V30 65 1 68 69
M  V30 66 1 69 70
M  V30 67 1 7 8
M  V30 68 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000481A1-20220106-C00005

>  <Row No>
433

$$$$
US20220000481A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00045001.cdx

>  <name>
US20220000481A1-20220106-C00006

>  <Row No>
434

$$$$
US20220000481A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 35 34 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.1142 0.7428 0.0 0
M  V30 3 O 1.0487 2.2285 0.0 0
M  V30 4 C 2.2285 0.131 0.0 0
M  V30 5 C 2.163 2.9714 0.0 0
M  V30 6 C 3.3428 0.8739 0.0 0
M  V30 7 C 2.163 -1.1798 0.0 0
M  V30 8 C 2.0974 4.4571 0.0 0
M  V30 9 C 3.2773 2.3596 0.0 0
M  V30 10 O 3.2117 5.2 0.0 0
M  V30 11 C 0.8521 5.2 0.0 0
M  V30 12 C 5.9647 4.1075 0.0 0
M  V30 13 O -0.3932 4.5882 0.0 0
M  V30 14 O 5.8991 2.7966 0.0 0
M  V30 15 C 7.079 4.8504 0.0 0
M  V30 16 C -1.6386 5.3311 0.0 0
M  V30 17 O 8.3899 4.2386 0.0 0
M  V30 18 O -2.884 4.7193 0.0 0
M  V30 19 ? 9.8538 5.0689 0.0 0
M  V30 20 C -4.4134 5.484 0.0 0
M  V30 21 O -4.479 6.9697 0.0 0
M  V30 22 C -5.6588 4.8722 0.0 0
M  V30 23 O -6.9042 5.6151 0.0 0
M  V30 24 C -9.3512 4.61 0.0 0
M  V30 25 C -10.5966 5.3529 0.0 0
M  V30 26 O -11.842 4.7411 0.0 0
M  V30 27 C -10.6622 6.8386 0.0 0
M  V30 28 ? -13.0874 5.484 0.0 0
M  V30 29 O -11.9075 7.5815 0.0 0
M  V30 30 C -9.5479 7.5815 0.0 0
M  V30 31 C -11.9731 9.0672 0.0 0
M  V30 32 O -10.8588 9.8101 0.0 0
M  V30 33 C -13.2185 9.8101 0.0 0
M  V30 34 C -14.4638 9.1983 0.0 0
M  V30 35 C -13.284 11.2958 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 8 10
M  V30 10 1 8 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 2 12 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 2 20 21
M  V30 21 1 20 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 26 1 25 27
M  V30 27 1 26 28
M  V30 28 1 27 29
M  V30 29 1 27 30
M  V30 30 1 29 31
M  V30 31 2 31 32
M  V30 32 1 31 33
M  V30 33 2 33 34
M  V30 34 1 33 35
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00046001.cdx

>  <name>
US20220000481A1-20220106-C00007

>  <Row No>
435

$$$$
US20220000662A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0 CHG=-1
M  V30 2 N -0.1847 -1.2005 0.0 0 CHG=1
M  V30 3 C -1.5122 -0.404 0.0 0
M  V30 4 C 1.0735 -0.404 0.0 0
M  V30 5 C -0.9696 -2.4588 0.0 0
M  V30 6 C 0.5194 -2.4588 0.0 0
M  V30 7 C -2.8398 -1.1082 0.0 0
M  V30 8 C -4.1673 -0.3116 0.0 0
M  V30 9 C -2.8744 -2.5627 0.0 0
M  V30 10 C -5.4949 -1.0158 0.0 0
M  V30 11 C -4.202 -3.29 0.0 0
M  V30 12 C -5.5295 -2.4704 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 3
M  V30 2 1 2 4
M  V30 3 1 2 5
M  V30 4 1 2 6
M  V30 5 1 3 7
M  V30 6 2 7 8
M  V30 7 1 7 9
M  V30 8 1 8 10
M  V30 9 2 9 11
M  V30 10 2 10 12
M  V30 11 1 11 12
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000662A1-20220106-C00001

>  <Row No>
436

$$$$
US20220000721A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 107 105 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.018 -1.4822 0.0 0
M  V30 3 O 1.2291 -2.1871 0.0 0
M  V30 4 N -1.3376 -2.2233 0.0 0
M  V30 5 C 2.4764 -1.3737 0.0 0
M  V30 6 C -2.6571 -1.446 0.0 0
M  V30 7 C 3.7236 -2.0787 0.0 0
M  V30 8 C -3.9767 -2.1871 0.0 0
M  V30 9 O 4.9709 -1.2653 0.0 0
M  V30 10 C -5.2962 -1.4099 0.0 0
M  V30 11 C 6.2181 -1.9702 0.0 0
M  V30 12 C -6.6338 -2.1148 0.0 0
M  V30 13 C -5.3505 0.1446 0.0 0
M  V30 14 ? -5.3143 -2.8921 0.0 0
M  V30 15 O 6.1639 -3.4163 0.0 0
M  V30 16 C 7.4653 -1.1568 0.0 0
M  V30 17 C -7.9715 -1.3014 0.0 0
M  V30 18 C 8.7126 -1.8618 0.0 0
M  V30 19 C 7.4111 0.3976 0.0 0
M  V30 20 C -9.3091 -2.0064 0.0 0
M  V30 21 C -8.0257 0.253 0.0 0
M  V30 22 ? -8.0257 -2.7475 0.0 0
M  V30 23 C -10.6467 -1.193 0.0 0
M  V30 24 C -11.9843 -1.8979 0.0 0
M  V30 25 O -12.0386 -3.344 0.0 0
M  V30 26 O -13.322 -1.0845 0.0 0
M  V30 27 C -14.6596 -1.7895 0.0 0
M  V30 28 C -15.9972 -0.9761 0.0 0
M  V30 29 O -17.3349 -1.681 0.0 0
M  V30 30 C -18.6725 -0.8676 0.0 0
M  V30 31 O -18.7267 0.6868 0.0 0
M  V30 32 C -20.0101 -1.5726 0.0 0
M  V30 33 C -21.3477 -0.7591 0.0 0
M  V30 34 C -20.0643 -3.0186 0.0 0
M  V30 35 O 4.9166 13.0147 0.0 0
M  V30 36 C 4.8624 11.5686 0.0 0
M  V30 37 O 3.5248 10.8636 0.0 0
M  V30 38 C 6.1096 10.8636 0.0 0
M  V30 39 C 2.1871 11.6771 0.0 0
M  V30 40 C 7.3569 11.6771 0.0 0
M  V30 41 C 6.0554 9.4176 0.0 0
M  V30 42 C 0.8495 10.9721 0.0 0
M  V30 43 O 0.7953 9.526 0.0 0
M  V30 44 C -0.488 11.7855 0.0 0
M  V30 45 O -1.8256 11.0805 0.0 0
M  V30 46 C -3.1633 11.894 0.0 0
M  V30 47 C -4.5009 11.189 0.0 0
M  V30 48 C -3.2175 13.4485 0.0 0
M  V30 49 C -5.8385 12.0024 0.0 0
M  V30 50 C -4.5551 14.2619 0.0 0
M  V30 51 C -5.8927 13.557 0.0 0
M  V30 52 C -7.2304 14.3704 0.0 0
M  V30 53 C -8.568 13.6654 0.0 0
M  V30 54 C -8.0438 15.708 0.0 0
M  V30 55 C -6.5254 15.708 0.0 0
M  V30 56 C -8.6222 12.2193 0.0 0
M  V30 57 C -9.9056 14.4788 0.0 0
M  V30 58 C -9.9598 11.5144 0.0 0
M  V30 59 C -11.2432 13.7739 0.0 0
M  V30 60 C -11.2975 12.3278 0.0 0
M  V30 61 O -12.6351 11.6228 0.0 0
M  V30 62 C -13.9727 12.4362 0.0 0
M  V30 63 C -15.3103 11.7313 0.0 0
M  V30 64 O -15.3646 10.2852 0.0 0
M  V30 65 C -16.648 12.5447 0.0 0
M  V30 66 O -17.9856 11.8397 0.0 0
M  V30 67 C -19.3232 12.6532 0.0 0
M  V30 68 O -19.3774 14.2077 0.0 0
M  V30 69 C -20.6608 11.9482 0.0 0
M  V30 70 C -21.9985 12.7616 0.0 0
M  V30 71 C -20.7151 10.5021 0.0 0
M  V30 72 O -18.5098 -6.6519 0.0 0
M  V30 73 C -18.564 -8.098 0.0 0
M  V30 74 O -17.3168 -8.803 0.0 0
M  V30 75 C -19.9016 -8.803 0.0 0
M  V30 76 C -16.0695 -7.9895 0.0 0
M  V30 77 C -21.2393 -7.9895 0.0 0
M  V30 78 C -19.9559 -10.2491 0.0 0
M  V30 79 C -14.8223 -8.6945 0.0 0
M  V30 80 O -14.8765 -10.1406 0.0 0
M  V30 81 C -13.575 -7.8811 0.0 0
M  V30 82 O -12.3278 -8.5861 0.0 0
M  V30 83 C -11.0805 -7.7726 0.0 0
M  V30 84 O -11.1348 -6.2181 0.0 0
M  V30 85 C -9.8333 -8.4776 0.0 0
M  V30 86 C -8.5861 -7.6642 0.0 0
M  V30 87 C -9.8875 -9.9237 0.0 0
M  V30 88 O -18.5098 6.7965 0.0 0
M  V30 89 C -18.564 5.3505 0.0 0
M  V30 90 O -17.3168 4.6455 0.0 0
M  V30 91 C -19.9016 4.6455 0.0 0
M  V30 92 C -16.0695 5.4589 0.0 0
M  V30 93 C -21.2393 5.4589 0.0 0
M  V30 94 C -19.9559 3.1994 0.0 0
M  V30 95 C -14.8223 4.7539 0.0 0
M  V30 96 O -13.575 5.5674 0.0 0
M  V30 97 C -12.3278 4.8624 0.0 0
M  V30 98 C -11.0805 5.6758 0.0 0
M  V30 99 O -9.8333 4.9709 0.0 0
M  V30 100 C -8.5861 5.7843 0.0 0
M  V30 101 C -7.3388 5.0793 0.0 0
M  V30 102 O -6.0916 5.8927 0.0 0
M  V30 103 C -4.8443 5.1878 0.0 0
M  V30 104 O -4.8986 3.7417 0.0 0
M  V30 105 C -3.5971 6.0012 0.0 0
M  V30 106 C -2.3498 5.2962 0.0 0
M  V30 107 C -3.6513 7.5557 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 2 11 15
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 2 16 18
M  V30 18 1 16 19
M  V30 19 1 17 20
M  V30 20 1 17 21
M  V30 21 1 17 22
M  V30 22 1 20 23
M  V30 23 1 23 24
M  V30 24 2 24 25
M  V30 25 1 24 26
M  V30 26 1 26 27
M  V30 27 1 27 28
M  V30 28 1 28 29
M  V30 29 1 29 30
M  V30 30 2 30 31
M  V30 31 1 30 32
M  V30 32 2 32 33
M  V30 33 1 32 34
M  V30 34 2 35 36
M  V30 35 1 36 37
M  V30 36 1 36 38
M  V30 37 1 37 39
M  V30 38 2 38 40
M  V30 39 1 38 41
M  V30 40 1 39 42
M  V30 41 1 42 43
M  V30 42 1 42 44
M  V30 43 1 44 45
M  V30 44 1 45 46
M  V30 45 2 46 47
M  V30 46 1 46 48
M  V30 47 1 47 49
M  V30 48 2 48 50
M  V30 49 2 49 51
M  V30 50 1 51 52
M  V30 51 1 52 53
M  V30 52 1 52 54
M  V30 53 1 52 55
M  V30 54 2 53 56
M  V30 55 1 53 57
M  V30 56 1 56 58
M  V30 57 2 57 59
M  V30 58 2 58 60
M  V30 59 1 60 61
M  V30 60 1 61 62
M  V30 61 1 62 63
M  V30 62 1 63 64
M  V30 63 1 63 65
M  V30 64 1 65 66
M  V30 65 1 66 67
M  V30 66 2 67 68
M  V30 67 1 67 69
M  V30 68 2 69 70
M  V30 69 1 69 71
M  V30 70 2 72 73
M  V30 71 1 73 74
M  V30 72 1 73 75
M  V30 73 1 74 76
M  V30 74 2 75 77
M  V30 75 1 75 78
M  V30 76 1 76 79
M  V30 77 1 79 80
M  V30 78 1 79 81
M  V30 79 1 81 82
M  V30 80 1 82 83
M  V30 81 2 83 84
M  V30 82 1 83 85
M  V30 83 2 85 86
M  V30 84 1 85 87
M  V30 85 2 88 89
M  V30 86 1 89 90
M  V30 87 1 89 91
M  V30 88 1 90 92
M  V30 89 2 91 93
M  V30 90 1 91 94
M  V30 91 1 92 95
M  V30 92 1 95 96
M  V30 93 1 96 97
M  V30 94 1 97 98
M  V30 95 1 98 99
M  V30 96 1 99 100
M  V30 97 1 100 101
M  V30 98 1 101 102
M  V30 99 1 102 103
M  V30 100 2 103 104
M  V30 101 1 103 105
M  V30 102 2 105 106
M  V30 103 1 105 107
M  V30 104 1 50 51
M  V30 105 1 59 60
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000721A1-20220106-C00002

>  <Row No>
437

$$$$
US20220000721A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 293 291 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.1458 1.7019 0.0 0
M  V30 3 N 1.0211 2.6258 0.0 0
M  V30 4 C -1.6046 2.6258 0.0 0
M  V30 5 C 0.8752 4.3277 0.0 0
M  V30 6 C 2.1882 1.9937 0.0 0
M  V30 7 C -3.0634 1.9937 0.0 0
M  V30 8 C -1.7505 4.3277 0.0 0
M  V30 9 C 2.0423 5.2517 0.0 0
M  V30 10 C 3.3552 2.9176 0.0 0
M  V30 11 C 3.2093 4.6195 0.0 0
M  V30 12 C 1.8964 6.9536 0.0 0
M  V30 13 N 4.5223 2.2854 0.0 0
M  V30 14 C 4.3764 5.5434 0.0 0
M  V30 15 C 3.0634 7.8775 0.0 0
M  V30 16 C 5.6893 3.2093 0.0 0
M  V30 17 C 4.3764 0.8752 0.0 0
M  V30 18 C 4.2305 7.2454 0.0 0
M  V30 19 O 5.5434 4.9113 0.0 0
M  V30 20 C 6.8564 2.5772 0.0 0
M  V30 21 C 2.9176 0.2431 0.0 0
M  V30 22 C 8.0234 3.5011 0.0 0
M  V30 23 C 6.7105 1.167 0.0 0
M  V30 24 C 1.4588 1.167 0.0 0
M  V30 25 C 2.7717 -1.167 0.0 0
M  V30 26 C 0.0 0.5348 0.0 0
M  V30 27 C 1.3129 -1.7991 0.0 0
M  V30 28 C -0.1458 -0.8752 0.0 0
M  V30 29 O 12.4485 1.167 0.0 0
M  V30 30 C 12.3026 2.8689 0.0 0
M  V30 31 N 13.4696 3.7929 0.0 0
M  V30 32 C 10.8438 3.7929 0.0 0
M  V30 33 C 13.3237 5.4948 0.0 0
M  V30 34 C 14.6367 3.1607 0.0 0
M  V30 35 C 9.385 3.1607 0.0 0
M  V30 36 C 10.6979 5.4948 0.0 0
M  V30 37 C 14.4908 6.4187 0.0 0
M  V30 38 C 15.8037 4.0846 0.0 0
M  V30 39 C 15.6578 5.7866 0.0 0
M  V30 40 C 14.3449 8.1207 0.0 0
M  V30 41 C 16.9708 3.4525 0.0 0
M  V30 42 C 16.8249 6.7105 0.0 0
M  V30 43 C 15.512 9.0446 0.0 0
M  V30 44 C 18.1378 4.3764 0.0 0
M  V30 45 C 16.679 8.4124 0.0 0
M  V30 46 O 19.3049 3.7442 0.0 0
M  V30 47 C 20.4719 4.6681 0.0 0
M  V30 48 C 21.6389 4.036 0.0 0
M  V30 49 C 22.806 4.9599 0.0 0
M  V30 50 C 23.973 4.3277 0.0 0
M  V30 51 N 25.1401 5.2517 0.0 0
M  V30 52 C 26.3071 4.6195 0.0 0
M  V30 53 C 24.9942 6.9536 0.0 0
M  V30 54 O 26.1613 3.2093 0.0 0
M  V30 55 C 27.4742 5.5434 0.0 0
M  V30 56 C 23.5354 7.8775 0.0 0
M  V30 57 C 28.6412 4.9113 0.0 0
M  V30 58 C 27.3283 7.2454 0.0 0
M  V30 59 C 23.3895 9.5795 0.0 0
M  V30 60 C 22.0766 7.2454 0.0 0
M  V30 61 C 21.9307 10.5034 0.0 0
M  V30 62 C 20.6178 8.1693 0.0 0
M  V30 63 C 20.4719 9.8712 0.0 0
M  V30 64 O 3.1121 -28.7871 0.0 0
M  V30 65 C 4.5223 -28.6412 0.0 0
M  V30 66 N 5.1544 -27.1824 0.0 0
M  V30 67 C 5.1544 -29.8083 0.0 0
M  V30 68 C 3.6956 -26.2585 0.0 0
M  V30 69 C 6.3215 -26.2585 0.0 0
M  V30 70 C 4.2305 -30.9753 0.0 0
M  V30 71 C 6.5646 -29.6624 0.0 0
M  V30 72 C 2.2368 -26.8907 0.0 0
M  V30 73 C 7.4885 -26.8907 0.0 0
M  V30 74 C 0.778 -25.9667 0.0 0
M  V30 75 C 8.6555 -25.9667 0.0 0
M  V30 76 N -0.6807 -26.5989 0.0 0
M  V30 77 N 9.8226 -26.5989 0.0 0
M  V30 78 C -2.1395 -25.675 0.0 0
M  V30 79 C -0.8266 -28.0091 0.0 0
M  V30 80 C 10.9896 -25.675 0.0 0
M  V30 81 C 9.6767 -28.0091 0.0 0
M  V30 82 O -2.2854 -23.973 0.0 0
M  V30 83 C -3.5983 -26.3071 0.0 0
M  V30 84 O 10.8438 -23.973 0.0 0
M  V30 85 C 12.1567 -26.3071 0.0 0
M  V30 86 C -5.0572 -25.3832 0.0 0
M  V30 87 C -3.7442 -27.7173 0.0 0
M  V30 88 C 13.3237 -25.3832 0.0 0
M  V30 89 C 12.0108 -27.7173 0.0 0
M  V30 90 O 16.7276 -13.2265 0.0 0
M  V30 91 C 16.5817 -14.6367 0.0 0
M  V30 92 N 17.7488 -15.2688 0.0 0
M  V30 93 C 15.1229 -15.2688 0.0 0
M  V30 94 C 18.9158 -14.3449 0.0 0
M  V30 95 C 17.6029 -16.679 0.0 0
M  V30 96 C 13.6641 -14.3449 0.0 0
M  V30 97 C 14.9771 -16.679 0.0 0
M  V30 98 C 20.0829 -14.9771 0.0 0
M  V30 99 C 18.77 -17.3111 0.0 0
M  V30 100 C 19.937 -16.3872 0.0 0
M  V30 101 C 21.2499 -14.0531 0.0 0
M  V30 102 C 21.1041 -17.0194 0.0 0
M  V30 103 C 22.417 -14.6853 0.0 0
M  V30 104 C 22.2711 -16.0955 0.0 0
M  V30 105 C 23.4381 -16.7276 0.0 0
M  V30 106 N 24.6052 -15.8037 0.0 0
M  V30 107 C 25.7722 -16.4359 0.0 0
M  V30 108 C 24.4593 -14.1018 0.0 0
M  V30 109 O 25.6264 -17.846 0.0 0
M  V30 110 C 26.9393 -15.512 0.0 0
M  V30 111 C 23.0005 -13.1779 0.0 0
M  V30 112 C 28.1063 -16.1441 0.0 0
M  V30 113 C 26.7934 -13.81 0.0 0
M  V30 114 O -1.167 -49.0159 0.0 0
M  V30 115 C -1.3129 -50.4261 0.0 0
M  V30 116 N -0.1458 -51.0583 0.0 0
M  V30 117 C -2.7717 -51.0583 0.0 0
M  V30 118 C 1.0211 -50.1343 0.0 0
M  V30 119 C -0.2917 -52.4684 0.0 0
M  V30 120 C -4.2305 -50.1343 0.0 0
M  V30 121 C -2.9176 -52.4684 0.0 0
M  V30 122 C 2.1882 -50.7665 0.0 0
M  V30 123 C 0.8752 -53.1006 0.0 0
M  V30 124 C 3.3552 -49.8426 0.0 0
M  V30 125 N 4.5223 -50.4747 0.0 0
M  V30 126 C 5.6893 -49.5508 0.0 0
M  V30 127 C 4.3764 -51.8849 0.0 0
M  V30 128 O 5.5434 -47.8489 0.0 0
M  V30 129 C 6.8564 -50.183 0.0 0
M  V30 130 C 5.5434 -52.5171 0.0 0
M  V30 131 C 8.0234 -49.2591 0.0 0
M  V30 132 C 6.7105 -51.5932 0.0 0
M  V30 133 O -1.167 -13.2265 0.0 0
M  V30 134 C -1.3129 -14.6367 0.0 0
M  V30 135 N -0.1458 -15.2688 0.0 0
M  V30 136 C -2.7717 -15.2688 0.0 0
M  V30 137 C 1.0211 -14.3449 0.0 0
M  V30 138 C -0.2917 -16.679 0.0 0
M  V30 139 C -4.2305 -14.3449 0.0 0
M  V30 140 C -2.9176 -16.679 0.0 0
M  V30 141 C 2.1882 -14.9771 0.0 0
M  V30 142 C 2.0423 -16.3872 0.0 0
M  V30 143 C 3.3552 -14.0531 0.0 0
M  V30 144 C 3.2093 -17.0194 0.0 0
M  V30 145 C 4.5223 -14.6853 0.0 0
M  V30 146 C 4.3764 -16.0955 0.0 0
M  V30 147 C 5.5434 -16.7276 0.0 0
M  V30 148 N 6.7105 -15.8037 0.0 0
M  V30 149 C 7.8775 -16.4359 0.0 0
M  V30 150 C 6.5646 -14.1018 0.0 0
M  V30 151 O 7.7316 -17.846 0.0 0
M  V30 152 C 9.0446 -15.512 0.0 0
M  V30 153 C 10.2116 -16.1441 0.0 0
M  V30 154 C 8.8987 -13.81 0.0 0
M  V30 155 O 13.6155 -9.7253 0.0 0
M  V30 156 C 13.4696 -8.0234 0.0 0
M  V30 157 N 14.6367 -7.0995 0.0 0
M  V30 158 C 12.0108 -7.0995 0.0 0
M  V30 159 C 15.8037 -7.7316 0.0 0
M  V30 160 C 14.4908 -5.3975 0.0 0
M  V30 161 C 10.552 -7.7316 0.0 0
M  V30 162 C 11.8649 -5.3975 0.0 0
M  V30 163 C 16.9708 -6.8077 0.0 0
M  V30 164 C 18.1378 -7.4399 0.0 0
M  V30 165 C 16.8249 -5.1058 0.0 0
M  V30 166 C 19.3049 -6.516 0.0 0
M  V30 167 C 20.4719 -7.1481 0.0 0
M  V30 168 C 18.3809 -5.0572 0.0 0
M  V30 169 C 19.937 -5.0572 0.0 0
M  V30 170 C 21.6389 -6.2242 0.0 0
M  V30 171 N 22.806 -6.8564 0.0 0
M  V30 172 C 23.973 -5.9324 0.0 0
M  V30 173 C 22.6601 -8.2665 0.0 0
M  V30 174 O 23.8272 -4.2305 0.0 0
M  V30 175 C 25.1401 -6.5646 0.0 0
M  V30 176 C 26.3071 -5.6407 0.0 0
M  V30 177 C 24.9942 -7.9748 0.0 0
M  V30 178 O 13.6155 -49.0159 0.0 0
M  V30 179 C 13.4696 -50.4261 0.0 0
M  V30 180 N 14.6367 -51.0583 0.0 0
M  V30 181 C 12.0108 -51.0583 0.0 0
M  V30 182 C 15.8037 -50.1343 0.0 0
M  V30 183 C 14.4908 -52.4684 0.0 0
M  V30 184 C 10.552 -50.1343 0.0 0
M  V30 185 C 11.8649 -52.4684 0.0 0
M  V30 186 C 16.9708 -50.7665 0.0 0
M  V30 187 C 18.1378 -49.8426 0.0 0
M  V30 188 N 19.3049 -50.4747 0.0 0
M  V30 189 C 20.4719 -49.5508 0.0 0
M  V30 190 C 19.159 -51.8849 0.0 0
M  V30 191 O 20.326 -47.8489 0.0 0
M  V30 192 C 21.6389 -50.183 0.0 0
M  V30 193 C 22.806 -49.2591 0.0 0
M  V30 194 C 21.4931 -51.5932 0.0 0
M  V30 195 O 7.0022 -6.6132 0.0 0
M  V30 196 C 6.8564 -8.0234 0.0 0
M  V30 197 N 5.3975 -8.6555 0.0 0
M  V30 198 C 8.0234 -8.6555 0.0 0
M  V30 199 C 3.9387 -7.7316 0.0 0
M  V30 200 C 9.1904 -7.7316 0.0 0
M  V30 201 C 7.8775 -10.0657 0.0 0
M  V30 202 C 2.4799 -8.3638 0.0 0
M  V30 203 C 3.7929 -6.0297 0.0 0
M  V30 204 C 5.3003 -7.1967 0.0 0
M  V30 205 C 1.0211 -7.4399 0.0 0
M  V30 206 C 1.2643 -9.2877 0.0 0
M  V30 207 C 3.4038 -9.2877 0.0 0
M  V30 208 C 2.334 -5.1058 0.0 0
M  V30 209 C 0.8752 -5.7379 0.0 0
M  V30 210 C 2.1882 -3.4038 0.0 0
M  V30 211 N -0.5835 -4.814 0.0 0
M  V30 212 C -2.0423 -5.4462 0.0 0
M  V30 213 O -2.1882 -6.8564 0.0 0
M  V30 214 C -3.5011 -4.5223 0.0 0
M  V30 215 C -4.9599 -5.1544 0.0 0
M  V30 216 C -3.647 -2.8203 0.0 0
M  V30 217 O 19.4507 -25.675 0.0 0
M  V30 218 C 19.3049 -27.0852 0.0 0
M  V30 219 N 20.4719 -27.7173 0.0 0
M  V30 220 C 17.846 -27.7173 0.0 0
M  V30 221 C 21.6389 -26.7934 0.0 0
M  V30 222 C 16.3872 -26.7934 0.0 0
M  V30 223 C 17.7002 -29.1275 0.0 0
M  V30 224 C 22.806 -27.4256 0.0 0
M  V30 225 C 23.4381 -25.9667 0.0 0
M  V30 226 C 23.973 -28.0577 0.0 0
M  V30 227 C 23.4381 -28.5926 0.0 0
M  V30 228 N 22.5142 -24.5079 0.0 0
M  V30 229 N 25.1401 -27.1338 0.0 0
M  V30 230 N 22.5142 -29.7596 0.0 0
M  V30 231 C 23.1464 -23.0491 0.0 0
M  V30 232 C 26.3071 -27.7659 0.0 0
M  V30 233 C 23.1464 -30.9267 0.0 0
M  V30 234 O 24.5566 -22.9032 0.0 0
M  V30 235 C 22.2225 -21.5903 0.0 0
M  V30 236 O 26.1613 -29.1761 0.0 0
M  V30 237 C 27.4742 -26.842 0.0 0
M  V30 238 O 24.5566 -30.7808 0.0 0
M  V30 239 C 22.2225 -32.0937 0.0 0
M  V30 240 C 22.8546 -20.1315 0.0 0
M  V30 241 C 20.5205 -21.4444 0.0 0
M  V30 242 C 28.6412 -27.4742 0.0 0
M  V30 243 C 27.3283 -25.1401 0.0 0
M  V30 244 C 22.8546 -33.2608 0.0 0
M  V30 245 C 20.5205 -31.9479 0.0 0
M  V30 246 O -1.167 -40.8466 0.0 0
M  V30 247 C -1.3129 -42.2568 0.0 0
M  V30 248 N -0.1458 -42.8889 0.0 0
M  V30 249 C -2.7717 -42.8889 0.0 0
M  V30 250 C 1.0211 -41.965 0.0 0
M  V30 251 C -4.2305 -41.965 0.0 0
M  V30 252 C -2.9176 -44.2991 0.0 0
M  V30 253 C 2.1882 -42.5972 0.0 0
M  V30 254 C 2.8203 -41.1384 0.0 0
M  V30 255 C 3.3552 -43.2293 0.0 0
M  V30 256 C 2.8203 -43.7642 0.0 0
M  V30 257 N 1.8964 -39.6795 0.0 0
M  V30 258 N 4.5223 -42.3054 0.0 0
M  V30 259 C 1.8964 -44.9313 0.0 0
M  V30 260 C 2.5286 -38.2207 0.0 0
M  V30 261 C 5.6893 -42.9376 0.0 0
M  V30 262 O 3.9387 -38.0749 0.0 0
M  V30 263 C 1.6046 -36.7619 0.0 0
M  V30 264 O 5.5434 -44.3477 0.0 0
M  V30 265 C 6.8564 -42.0136 0.0 0
M  V30 266 C 2.2368 -35.3031 0.0 0
M  V30 267 C -0.0972 -36.6161 0.0 0
M  V30 268 C 8.0234 -42.6458 0.0 0
M  V30 269 C 6.7105 -40.3117 0.0 0
M  V30 270 O 14.3935 -38.9015 0.0 0
M  V30 271 C 14.2476 -40.3117 0.0 0
M  V30 272 N 15.4147 -40.9439 0.0 0
M  V30 273 C 12.7888 -40.9439 0.0 0
M  V30 274 C 16.5817 -40.0199 0.0 0
M  V30 275 C 11.33 -40.0199 0.0 0
M  V30 276 C 12.643 -42.354 0.0 0
M  V30 277 C 17.7488 -40.6521 0.0 0
M  V30 278 C 18.9158 -39.7282 0.0 0
M  V30 279 C 17.6029 -42.0623 0.0 0
M  V30 280 C 20.0829 -40.3603 0.0 0
M  V30 281 C 19.159 -41.0897 0.0 0
M  V30 282 C 18.77 -42.6944 0.0 0
M  V30 283 C 19.937 -41.7705 0.0 0
M  V30 284 C 21.3958 -39.7282 0.0 0
M  V30 285 C 21.2499 -42.1109 0.0 0
M  V30 286 C 22.1738 -40.8466 0.0 0
M  V30 287 C 22.417 -42.743 0.0 0
M  V30 288 N 23.584 -41.8191 0.0 0
M  V30 289 C 24.7511 -42.4513 0.0 0
M  V30 290 O 24.6052 -43.8615 0.0 0
M  V30 291 C 25.9181 -41.5274 0.0 0
M  V30 292 C 27.0852 -42.1595 0.0 0
M  V30 293 C 25.7722 -39.8254 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 2 9 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 13 16
M  V30 16 1 13 17
M  V30 17 2 14 18
M  V30 18 2 16 19
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 2 20 22
M  V30 22 1 20 23
M  V30 23 2 21 24
M  V30 24 1 21 25
M  V30 25 1 24 26
M  V30 26 2 25 27
M  V30 27 2 26 28
M  V30 28 2 29 30
M  V30 29 1 30 31
M  V30 30 1 30 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 2 32 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 2 37 39
M  V30 38 1 37 40
M  V30 39 1 38 41
M  V30 40 1 39 42
M  V30 41 2 40 43
M  V30 42 1 41 44
M  V30 43 2 42 45
M  V30 44 1 44 46
M  V30 45 1 46 47
M  V30 46 1 47 48
M  V30 47 1 48 49
M  V30 48 1 49 50
M  V30 49 1 50 51
M  V30 50 1 51 52
M  V30 51 1 51 53
M  V30 52 2 52 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 2 55 57
M  V30 56 1 55 58
M  V30 57 2 56 59
M  V30 58 1 56 60
M  V30 59 1 59 61
M  V30 60 2 60 62
M  V30 61 2 61 63
M  V30 62 2 64 65
M  V30 63 1 65 66
M  V30 64 1 65 67
M  V30 65 1 66 68
M  V30 66 1 66 69
M  V30 67 2 67 70
M  V30 68 1 67 71
M  V30 69 1 68 72
M  V30 70 1 69 73
M  V30 71 1 72 74
M  V30 72 1 73 75
M  V30 73 1 74 76
M  V30 74 1 75 77
M  V30 75 1 76 78
M  V30 76 1 76 79
M  V30 77 1 77 80
M  V30 78 1 77 81
M  V30 79 2 78 82
M  V30 80 1 78 83
M  V30 81 2 80 84
M  V30 82 1 80 85
M  V30 83 2 83 86
M  V30 84 1 83 87
M  V30 85 2 85 88
M  V30 86 1 85 89
M  V30 87 2 90 91
M  V30 88 1 91 92
M  V30 89 1 91 93
M  V30 90 1 92 94
M  V30 91 1 92 95
M  V30 92 2 93 96
M  V30 93 1 93 97
M  V30 94 1 94 98
M  V30 95 1 95 99
M  V30 96 1 98 100
M  V30 97 1 98 101
M  V30 98 1 100 102
M  V30 99 1 101 103
M  V30 100 1 102 104
M  V30 101 1 104 105
M  V30 102 1 105 106
M  V30 103 1 106 107
M  V30 104 1 106 108
M  V30 105 2 107 109
M  V30 106 1 107 110
M  V30 107 1 108 111
M  V30 108 2 110 112
M  V30 109 1 110 113
M  V30 110 2 114 115
M  V30 111 1 115 116
M  V30 112 1 115 117
M  V30 113 1 116 118
M  V30 114 1 116 119
M  V30 115 2 117 120
M  V30 116 1 117 121
M  V30 117 1 118 122
M  V30 118 1 119 123
M  V30 119 1 122 124
M  V30 120 1 124 125
M  V30 121 1 125 126
M  V30 122 1 125 127
M  V30 123 2 126 128
M  V30 124 1 126 129
M  V30 125 1 127 130
M  V30 126 2 129 131
M  V30 127 1 129 132
M  V30 128 2 133 134
M  V30 129 1 134 135
M  V30 130 1 134 136
M  V30 131 1 135 137
M  V30 132 1 135 138
M  V30 133 2 136 139
M  V30 134 1 136 140
M  V30 135 1 137 141
M  V30 136 2 141 142
M  V30 137 1 141 143
M  V30 138 1 142 144
M  V30 139 2 143 145
M  V30 140 2 144 146
M  V30 141 1 146 147
M  V30 142 1 147 148
M  V30 143 1 148 149
M  V30 144 1 148 150
M  V30 145 2 149 151
M  V30 146 1 149 152
M  V30 147 2 152 153
M  V30 148 1 152 154
M  V30 149 2 155 156
M  V30 150 1 156 157
M  V30 151 1 156 158
M  V30 152 1 157 159
M  V30 153 1 157 160
M  V30 154 2 158 161
M  V30 155 1 158 162
M  V30 156 1 159 163
M  V30 157 1 163 164
M  V30 158 1 163 165
M  V30 159 1 164 166
M  V30 160 1 166 167
M  V30 161 1 166 168
M  V30 162 1 166 169
M  V30 163 1 167 170
M  V30 164 1 170 171
M  V30 165 1 171 172
M  V30 166 1 171 173
M  V30 167 2 172 174
M  V30 168 1 172 175
M  V30 169 2 175 176
M  V30 170 1 175 177
M  V30 171 2 178 179
M  V30 172 1 179 180
M  V30 173 1 179 181
M  V30 174 1 180 182
M  V30 175 1 180 183
M  V30 176 2 181 184
M  V30 177 1 181 185
M  V30 178 1 182 186
M  V30 179 1 186 187
M  V30 180 1 187 188
M  V30 181 1 188 189
M  V30 182 1 188 190
M  V30 183 2 189 191
M  V30 184 1 189 192
M  V30 185 2 192 193
M  V30 186 1 192 194
M  V30 187 2 195 196
M  V30 188 1 196 197
M  V30 189 1 196 198
M  V30 190 1 197 199
M  V30 191 2 198 200
M  V30 192 1 198 201
M  V30 193 1 199 202
M  V30 194 1 199 203
M  V30 195 1 199 204
M  V30 196 1 202 205
M  V30 197 1 202 206
M  V30 198 1 202 207
M  V30 199 1 203 208
M  V30 200 1 205 209
M  V30 201 1 208 210
M  V30 202 1 209 211
M  V30 203 1 211 212
M  V30 204 2 212 213
M  V30 205 1 212 214
M  V30 206 2 214 215
M  V30 207 1 214 216
M  V30 208 2 217 218
M  V30 209 1 218 219
M  V30 210 1 218 220
M  V30 211 1 219 221
M  V30 212 2 220 222
M  V30 213 1 220 223
M  V30 214 1 221 224
M  V30 215 1 224 225
M  V30 216 1 224 226
M  V30 217 1 224 227
M  V30 218 1 225 228
M  V30 219 1 226 229
M  V30 220 1 227 230
M  V30 221 1 228 231
M  V30 222 1 229 232
M  V30 223 1 230 233
M  V30 224 2 231 234
M  V30 225 1 231 235
M  V30 226 2 232 236
M  V30 227 1 232 237
M  V30 228 1 233 238
M  V30 229 1 233 239
M  V30 230 2 235 240
M  V30 231 1 235 241
M  V30 232 2 237 242
M  V30 233 1 237 243
M  V30 234 2 239 244
M  V30 235 1 239 245
M  V30 236 2 246 247
M  V30 237 1 247 248
M  V30 238 1 247 249
M  V30 239 1 248 250
M  V30 240 2 249 251
M  V30 241 1 249 252
M  V30 242 1 250 253
M  V30 243 1 253 254
M  V30 244 1 253 255
M  V30 245 1 253 256
M  V30 246 1 254 257
M  V30 247 1 255 258
M  V30 248 1 256 259
M  V30 249 1 257 260
M  V30 250 1 258 261
M  V30 251 2 260 262
M  V30 252 1 260 263
M  V30 253 2 261 264
M  V30 254 1 261 265
M  V30 255 2 263 266
M  V30 256 1 263 267
M  V30 257 2 265 268
M  V30 258 1 265 269
M  V30 259 2 270 271
M  V30 260 1 271 272
M  V30 261 1 271 273
M  V30 262 1 272 274
M  V30 263 2 273 275
M  V30 264 1 273 276
M  V30 265 1 274 277
M  V30 266 1 277 278
M  V30 267 1 277 279
M  V30 268 1 278 280
M  V30 269 1 278 281
M  V30 270 1 279 282
M  V30 271 1 280 283
M  V30 272 1 280 284
M  V30 273 1 283 285
M  V30 274 1 284 286
M  V30 275 1 285 287
M  V30 276 1 287 288
M  V30 277 1 288 289
M  V30 278 2 289 290
M  V30 279 1 289 291
M  V30 280 2 291 292
M  V30 281 1 291 293
M  V30 282 1 15 18
M  V30 283 1 27 28
M  V30 284 1 43 45
M  V30 285 1 62 63
M  V30 286 1 103 104
M  V30 287 1 145 146
M  V30 288 1 208 209
M  V30 289 1 281 282
M  V30 290 1 282 283
M  V30 291 1 285 286
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000721A1-20220106-C00004

>  <Row No>
438

$$$$
US20220000721A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 161 159 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0774 1.5741 0.0 0
M  V30 3 N 1.1354 2.3999 0.0 0
M  V30 4 C -1.4451 2.3999 0.0 0
M  V30 5 C 2.3483 1.7289 0.0 0
M  V30 6 C 1.058 3.974 0.0 0
M  V30 7 C -2.8128 1.7289 0.0 0
M  V30 8 C -1.5225 3.974 0.0 0
M  V30 9 C 3.5611 2.5547 0.0 0
M  V30 10 C 2.2708 4.7998 0.0 0
M  V30 11 O 3.4837 4.1288 0.0 0
M  V30 12 O -8.8771 0.6193 0.0 0
M  V30 13 C -8.9545 2.1934 0.0 0
M  V30 14 N -7.7416 3.0192 0.0 0
M  V30 15 C -10.3222 3.0192 0.0 0
M  V30 16 C -6.5288 2.3483 0.0 0
M  V30 17 C -7.819 4.5933 0.0 0
M  V30 18 C -11.6899 2.3483 0.0 0
M  V30 19 C -10.3996 4.5933 0.0 0
M  V30 20 C -5.3159 3.174 0.0 0
M  V30 21 C -6.6062 5.4191 0.0 0
M  V30 22 C -5.3933 4.7482 0.0 0
M  V30 23 O 7.8448 0.6193 0.0 0
M  V30 24 C 7.7674 2.1934 0.0 0
M  V30 25 N 8.9803 3.0192 0.0 0
M  V30 26 C 6.3997 3.0192 0.0 0
M  V30 27 C 10.1931 2.3483 0.0 0
M  V30 28 C 8.9029 4.5933 0.0 0
M  V30 29 C 5.032 2.3483 0.0 0
M  V30 30 C 6.3223 4.5933 0.0 0
M  V30 31 C 11.406 1.6773 0.0 0
M  V30 32 C 10.1157 3.9224 0.0 0
M  V30 33 C 9.3158 0.6193 0.0 0
M  V30 34 C 10.1157 5.4191 0.0 0
M  V30 35 C 12.6189 2.5031 0.0 0
M  V30 36 C 11.3286 4.7482 0.0 0
M  V30 37 C 10.606 1.316 0.0 0
M  V30 38 C 12.5415 4.0772 0.0 0
M  V30 39 C 11.6641 0.7483 0.0 0
M  V30 40 C 10.5286 3.6901 0.0 0
M  V30 41 O -8.8771 13.6253 0.0 0
M  V30 42 C -8.9545 15.1994 0.0 0
M  V30 43 N -7.7416 16.0252 0.0 0
M  V30 44 C -10.3222 16.0252 0.0 0
M  V30 45 C -7.819 17.5993 0.0 0
M  V30 46 C -6.5288 15.3543 0.0 0
M  V30 47 C -11.6899 15.3543 0.0 0
M  V30 48 C -10.3996 17.5993 0.0 0
M  V30 49 C -6.6062 18.4251 0.0 0
M  V30 50 C -9.1867 18.4251 0.0 0
M  V30 51 C -5.3159 16.18 0.0 0
M  V30 52 C -6.6836 19.9993 0.0 0
M  V30 53 C -9.2641 19.9993 0.0 0
M  V30 54 C -4.103 15.5091 0.0 0
M  V30 55 C -8.0513 20.825 0.0 0
M  V30 56 C -2.8902 16.3349 0.0 0
M  V30 57 O -6.1933 26.4248 0.0 0
M  V30 58 C -7.561 25.7539 0.0 0
M  V30 59 N -7.6384 24.3346 0.0 0
M  V30 60 C -8.9287 26.5797 0.0 0
M  V30 61 C -6.4255 23.6637 0.0 0
M  V30 62 C -9.0061 23.6637 0.0 0
M  V30 63 C -9.0061 28.1538 0.0 0
M  V30 64 C -10.2964 25.9087 0.0 0
M  V30 65 C -5.2127 24.4894 0.0 0
M  V30 66 C -10.3738 24.4894 0.0 0
M  V30 67 C -3.9998 23.8185 0.0 0
M  V30 68 C -11.7415 23.8185 0.0 0
M  V30 69 C -2.787 24.6443 0.0 0
M  V30 70 N -1.5741 23.9733 0.0 0
M  V30 71 C -1.6515 25.5475 0.0 0
M  V30 72 C -0.3612 24.7991 0.0 0
M  V30 73 O -3.0192 26.3732 0.0 0
M  V30 74 C -0.4386 26.3732 0.0 0
M  V30 75 C 0.8515 24.1282 0.0 0
M  V30 76 C -0.5161 27.9474 0.0 0
M  V30 77 C 0.7741 25.7023 0.0 0
M  V30 78 C 2.0644 24.9539 0.0 0
M  V30 79 O 2.0644 13.6253 0.0 0
M  V30 80 C 1.987 15.1994 0.0 0
M  V30 81 N 3.1998 16.0252 0.0 0
M  V30 82 C 0.6193 16.0252 0.0 0
M  V30 83 C 3.1224 17.5993 0.0 0
M  V30 84 C 4.4127 15.3543 0.0 0
M  V30 85 C -0.7483 15.3543 0.0 0
M  V30 86 C 0.5419 17.5993 0.0 0
M  V30 87 C 4.3353 18.4251 0.0 0
M  V30 88 C 5.6256 16.18 0.0 0
M  V30 89 C 5.5481 17.7542 0.0 0
M  V30 90 C 4.2579 19.9993 0.0 0
M  V30 91 C 6.8384 15.5091 0.0 0
M  V30 92 C 6.761 18.58 0.0 0
M  V30 93 C 5.4707 20.825 0.0 0
M  V30 94 C 8.0513 16.3349 0.0 0
M  V30 95 C 6.6836 20.1541 0.0 0
M  V30 96 C 9.2641 15.6639 0.0 0
M  V30 97 C 10.477 16.4897 0.0 0
M  V30 98 C 11.6899 15.8188 0.0 0
M  V30 99 O 19.6122 7.8448 0.0 0
M  V30 100 C 19.5348 9.419 0.0 0
M  V30 101 N 20.7476 10.2448 0.0 0
M  V30 102 C 18.1671 10.2448 0.0 0
M  V30 103 C 21.9605 9.5738 0.0 0
M  V30 104 C 20.6702 11.8189 0.0 0
M  V30 105 C 16.7994 9.5738 0.0 0
M  V30 106 C 18.0896 11.8189 0.0 0
M  V30 107 C 23.1733 10.3996 0.0 0
M  V30 108 C 21.8831 12.6447 0.0 0
M  V30 109 O 16.9284 0.6193 0.0 0
M  V30 110 C 16.851 2.1934 0.0 0
M  V30 111 N 18.0638 3.0192 0.0 0
M  V30 112 C 15.4833 3.0192 0.0 0
M  V30 113 C 19.2767 2.3483 0.0 0 CFG=2
M  V30 114 C 17.9864 4.5933 0.0 0
M  V30 115 C 14.1156 2.3483 0.0 0
M  V30 116 C 15.4059 4.5933 0.0 0
M  V30 117 C 20.4896 3.174 0.0 0
M  V30 118 C 19.1993 0.929 0.0 0
M  V30 119 C 21.7024 2.5031 0.0 0
M  V30 120 C 20.4121 4.7482 0.0 0
M  V30 121 C 22.9153 3.3289 0.0 0
M  V30 122 C 21.625 5.574 0.0 0
M  V30 123 C 22.8379 4.903 0.0 0
M  V30 124 O 7.432 22.9153 0.0 0
M  V30 125 C 7.3545 24.4894 0.0 0
M  V30 126 N 8.5674 25.3152 0.0 0
M  V30 127 C 5.9868 25.3152 0.0 0
M  V30 128 C 9.7803 24.6443 0.0 0
M  V30 129 C 8.49 26.8893 0.0 0
M  V30 130 C 4.6191 24.6443 0.0 0
M  V30 131 C 5.9094 26.8893 0.0 0
M  V30 132 C 10.9931 25.47 0.0 0
M  V30 133 C 12.206 24.7991 0.0 0
M  V30 134 C 13.4188 25.6249 0.0 0
M  V30 135 C 14.6317 24.9539 0.0 0
M  V30 136 C 15.8446 25.7797 0.0 0
M  V30 137 C 17.0574 25.1088 0.0 0
M  V30 138 O -8.8771 7.8448 0.0 0
M  V30 139 C -8.9545 9.419 0.0 0
M  V30 140 N -7.7416 10.2448 0.0 0
M  V30 141 C -10.3222 10.2448 0.0 0
M  V30 142 C -6.5288 9.5738 0.0 0
M  V30 143 C -11.6899 9.5738 0.0 0
M  V30 144 C -10.3996 11.8189 0.0 0
M  V30 145 C -5.3159 10.3996 0.0 0
M  V30 146 C -4.103 9.7286 0.0 0
M  V30 147 C -2.8902 10.5544 0.0 0
M  V30 148 C -1.6773 9.8835 0.0 0
M  V30 149 C -0.4645 10.7093 0.0 0
M  V30 150 C 0.7483 10.0383 0.0 0
M  V30 151 C 1.9612 10.8641 0.0 0
M  V30 152 C 3.174 10.1931 0.0 0
M  V30 153 C 4.3869 11.0189 0.0 0
M  V30 154 C 5.5998 10.348 0.0 0
M  V30 155 C 6.8126 11.1738 0.0 0
M  V30 156 C 8.0255 10.5028 0.0 0
M  V30 157 C 9.2383 11.3286 0.0 0
M  V30 158 C 10.4512 10.6576 0.0 0
M  V30 159 C 11.6641 11.4834 0.0 0
M  V30 160 C 12.8769 10.8125 0.0 0
M  V30 161 C 14.0898 11.6383 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 9 11
M  V30 11 2 12 13
M  V30 12 1 13 14
M  V30 13 1 13 15
M  V30 14 1 14 16
M  V30 15 1 14 17
M  V30 16 2 15 18
M  V30 17 1 15 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 20 22
M  V30 21 2 23 24
M  V30 22 1 24 25
M  V30 23 1 24 26
M  V30 24 1 25 27
M  V30 25 1 25 28
M  V30 26 2 26 29
M  V30 27 1 26 30
M  V30 28 1 27 31
M  V30 29 1 27 32
M  V30 30 1 27 33
M  V30 31 1 28 34
M  V30 32 1 31 35
M  V30 33 1 32 36
M  V30 34 1 33 37
M  V30 35 1 35 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 2 41 42
M  V30 39 1 42 43
M  V30 40 1 42 44
M  V30 41 1 43 45
M  V30 42 1 43 46
M  V30 43 2 44 47
M  V30 44 1 44 48
M  V30 45 1 45 49
M  V30 46 1 45 50
M  V30 47 1 46 51
M  V30 48 1 49 52
M  V30 49 1 50 53
M  V30 50 1 51 54
M  V30 51 1 52 55
M  V30 52 1 54 56
M  V30 53 2 57 58
M  V30 54 1 58 59
M  V30 55 1 58 60
M  V30 56 1 59 61
M  V30 57 1 59 62
M  V30 58 2 60 63
M  V30 59 1 60 64
M  V30 60 1 61 65
M  V30 61 1 62 66
M  V30 62 2 65 67
M  V30 63 2 66 68
M  V30 64 1 67 69
M  V30 65 1 69 70
M  V30 66 1 70 71
M  V30 67 1 70 72
M  V30 68 2 71 73
M  V30 69 1 71 74
M  V30 70 1 72 75
M  V30 71 2 74 76
M  V30 72 1 74 77
M  V30 73 2 75 78
M  V30 74 2 79 80
M  V30 75 1 80 81
M  V30 76 1 80 82
M  V30 77 1 81 83
M  V30 78 1 81 84
M  V30 79 2 82 85
M  V30 80 1 82 86
M  V30 81 1 83 87
M  V30 82 1 84 88
M  V30 83 2 87 89
M  V30 84 1 87 90
M  V30 85 1 88 91
M  V30 86 1 89 92
M  V30 87 2 90 93
M  V30 88 1 91 94
M  V30 89 2 92 95
M  V30 90 1 94 96
M  V30 91 1 96 97
M  V30 92 1 97 98
M  V30 93 2 99 100
M  V30 94 1 100 101
M  V30 95 1 100 102
M  V30 96 1 101 103
M  V30 97 1 101 104
M  V30 98 2 102 105
M  V30 99 1 102 106
M  V30 100 1 103 107
M  V30 101 1 104 108
M  V30 102 2 109 110
M  V30 103 1 110 111
M  V30 104 1 110 112
M  V30 105 1 111 113
M  V30 106 1 111 114
M  V30 107 2 112 115
M  V30 108 1 112 116
M  V30 109 1 113 117
M  V30 110 1 113 118 CFG=3
M  V30 111 2 117 119
M  V30 112 1 117 120
M  V30 113 1 119 121
M  V30 114 2 120 122
M  V30 115 2 121 123
M  V30 116 2 124 125
M  V30 117 1 125 126
M  V30 118 1 125 127
M  V30 119 1 126 128
M  V30 120 1 126 129
M  V30 121 2 127 130
M  V30 122 1 127 131
M  V30 123 1 128 132
M  V30 124 1 132 133
M  V30 125 1 133 134
M  V30 126 1 134 135
M  V30 127 1 135 136
M  V30 128 1 136 137
M  V30 129 2 138 139
M  V30 130 1 139 140
M  V30 131 1 139 141
M  V30 132 1 140 142
M  V30 133 2 141 143
M  V30 134 1 141 144
M  V30 135 1 142 145
M  V30 136 1 145 146
M  V30 137 1 146 147
M  V30 138 1 147 148
M  V30 139 1 148 149
M  V30 140 1 149 150
M  V30 141 1 150 151
M  V30 142 1 151 152
M  V30 143 1 152 153
M  V30 144 1 153 154
M  V30 145 1 154 155
M  V30 146 1 155 156
M  V30 147 1 156 157
M  V30 148 1 157 158
M  V30 149 1 158 159
M  V30 150 1 159 160
M  V30 151 1 160 161
M  V30 152 1 10 11
M  V30 153 1 21 22
M  V30 154 1 36 38
M  V30 155 1 37 39
M  V30 156 1 37 40
M  V30 157 1 53 55
M  V30 158 1 93 95
M  V30 159 1 122 123
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 113)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00025002.cdx

>  <name>
US20220000721A1-20220106-C00005

>  <Row No>
439

$$$$
US20220000721A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 265 263 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.1457 1.7007 0.0 0
M  V30 3 N 1.0204 2.6239 0.0 0
M  V30 4 C -1.6035 2.6239 0.0 0
M  V30 5 C 0.8746 4.3246 0.0 0
M  V30 6 C 2.1866 1.9922 0.0 0
M  V30 7 C -3.0612 1.9922 0.0 0
M  V30 8 C 2.0408 5.2479 0.0 0
M  V30 9 C 3.3528 2.9155 0.0 0
M  V30 10 C 3.207 4.6162 0.0 0
M  V30 11 C 1.895 6.9486 0.0 0
M  V30 12 N 4.519 2.2838 0.0 0
M  V30 13 C 4.3732 5.5394 0.0 0
M  V30 14 C 3.0612 7.8718 0.0 0
M  V30 15 C 5.6852 3.207 0.0 0
M  V30 16 C 4.3732 0.8746 0.0 0
M  V30 17 C 4.2274 7.2401 0.0 0
M  V30 18 O 5.5394 4.9077 0.0 0
M  V30 19 C 6.8514 2.5753 0.0 0
M  V30 20 C 2.9155 0.2429 0.0 0
M  V30 21 C 8.0176 3.4986 0.0 0
M  V30 22 C 1.4577 1.1662 0.0 0
M  V30 23 C 2.7697 -1.1662 0.0 0
M  V30 24 C 0.0 0.5345 0.0 0
M  V30 25 C 1.3119 -1.7978 0.0 0
M  V30 26 C -0.1457 -0.8746 0.0 0
M  V30 27 O 12.4394 1.1662 0.0 0
M  V30 28 C 12.2937 2.8669 0.0 0
M  V30 29 N 13.4599 3.7901 0.0 0
M  V30 30 C 10.8359 3.7901 0.0 0
M  V30 31 C 13.3141 5.4908 0.0 0
M  V30 32 C 14.6261 3.1584 0.0 0
M  V30 33 C 9.3782 3.1584 0.0 0
M  V30 34 C 14.4803 6.4141 0.0 0
M  V30 35 C 15.7923 4.0817 0.0 0
M  V30 36 C 15.6465 5.7824 0.0 0
M  V30 37 C 14.3345 8.1148 0.0 0
M  V30 38 C 16.9585 3.45 0.0 0
M  V30 39 C 16.8127 6.7056 0.0 0
M  V30 40 C 15.5007 9.038 0.0 0
M  V30 41 C 18.1247 4.3732 0.0 0
M  V30 42 C 16.6669 8.4063 0.0 0
M  V30 43 O 19.2909 3.7415 0.0 0
M  V30 44 C 20.4571 4.6648 0.0 0
M  V30 45 C 21.6233 4.0331 0.0 0
M  V30 46 C 22.7895 4.9563 0.0 0
M  V30 47 C 23.9557 4.3246 0.0 0
M  V30 48 N 25.1219 5.2479 0.0 0
M  V30 49 C 26.2881 4.6162 0.0 0
M  V30 50 C 24.9761 6.9486 0.0 0
M  V30 51 O 26.1423 3.207 0.0 0
M  V30 52 C 27.4543 5.5394 0.0 0
M  V30 53 C 23.5183 7.8718 0.0 0
M  V30 54 C 28.6205 4.9077 0.0 0
M  V30 55 C 23.3726 9.5725 0.0 0
M  V30 56 C 22.0606 7.2401 0.0 0
M  V30 57 C 21.9148 10.4958 0.0 0
M  V30 58 C 20.6028 8.1634 0.0 0
M  V30 59 C 20.4571 9.8641 0.0 0
M  V30 60 O 3.1098 -28.7662 0.0 0
M  V30 61 C 4.519 -28.6205 0.0 0
M  V30 62 N 5.1507 -27.1627 0.0 0
M  V30 63 C 5.1507 -29.7867 0.0 0
M  V30 64 C 3.6929 -26.2395 0.0 0
M  V30 65 C 6.3169 -26.2395 0.0 0
M  V30 66 C 4.2274 -30.9529 0.0 0
M  V30 67 C 2.2352 -26.8712 0.0 0
M  V30 68 C 7.4831 -26.8712 0.0 0
M  V30 69 C 0.7774 -25.9479 0.0 0
M  V30 70 C 8.6493 -25.9479 0.0 0
M  V30 71 N -0.6802 -26.5796 0.0 0
M  V30 72 N 9.8155 -26.5796 0.0 0
M  V30 73 C -2.138 -25.6564 0.0 0
M  V30 74 C -0.826 -27.9888 0.0 0
M  V30 75 C 10.9817 -25.6564 0.0 0
M  V30 76 C 9.6697 -27.9888 0.0 0
M  V30 77 O -2.2838 -23.9557 0.0 0
M  V30 78 C -3.5957 -26.2881 0.0 0
M  V30 79 O 10.8359 -23.9557 0.0 0
M  V30 80 C 12.1479 -26.2881 0.0 0
M  V30 81 C -5.0535 -25.3648 0.0 0
M  V30 82 C 13.3141 -25.3648 0.0 0
M  V30 83 O 16.7155 -13.2169 0.0 0
M  V30 84 C 16.5697 -14.6261 0.0 0
M  V30 85 N 17.7359 -15.2577 0.0 0
M  V30 86 C 15.112 -15.2577 0.0 0
M  V30 87 C 18.9021 -14.3345 0.0 0
M  V30 88 C 17.5902 -16.6669 0.0 0
M  V30 89 C 13.6542 -14.3345 0.0 0
M  V30 90 C 20.0683 -14.9662 0.0 0
M  V30 91 C 18.7564 -17.2986 0.0 0
M  V30 92 C 19.9226 -16.3754 0.0 0
M  V30 93 C 21.2345 -14.043 0.0 0
M  V30 94 C 21.0888 -17.0071 0.0 0
M  V30 95 C 22.4007 -14.6746 0.0 0
M  V30 96 C 22.255 -16.0838 0.0 0
M  V30 97 C 23.4212 -16.7155 0.0 0
M  V30 98 N 24.5874 -15.7923 0.0 0
M  V30 99 C 25.7536 -16.4239 0.0 0
M  V30 100 C 24.4416 -14.0915 0.0 0
M  V30 101 O 25.6078 -17.8331 0.0 0
M  V30 102 C 26.9198 -15.5007 0.0 0
M  V30 103 C 22.9838 -13.1683 0.0 0
M  V30 104 C 28.086 -16.1324 0.0 0
M  V30 105 O -1.1662 -48.9804 0.0 0
M  V30 106 C -1.3119 -50.3896 0.0 0
M  V30 107 N -0.1457 -51.0213 0.0 0
M  V30 108 C -2.7697 -51.0213 0.0 0
M  V30 109 C 1.0204 -50.098 0.0 0
M  V30 110 C -0.2915 -52.4304 0.0 0
M  V30 111 C -4.2274 -50.098 0.0 0
M  V30 112 C 2.1866 -50.7297 0.0 0
M  V30 113 C 0.8746 -53.0621 0.0 0
M  V30 114 C 3.3528 -49.8065 0.0 0
M  V30 115 N 4.519 -50.4381 0.0 0
M  V30 116 C 5.6852 -49.5149 0.0 0
M  V30 117 C 4.3732 -51.8473 0.0 0
M  V30 118 O 5.5394 -47.8142 0.0 0
M  V30 119 C 6.8514 -50.1466 0.0 0
M  V30 120 C 5.5394 -52.479 0.0 0
M  V30 121 C 8.0176 -49.2234 0.0 0
M  V30 122 O -1.1662 -13.2169 0.0 0
M  V30 123 C -1.3119 -14.6261 0.0 0
M  V30 124 N -0.1457 -15.2577 0.0 0
M  V30 125 C -2.7697 -15.2577 0.0 0
M  V30 126 C 1.0204 -14.3345 0.0 0
M  V30 127 C -0.2915 -16.6669 0.0 0
M  V30 128 C -4.2274 -14.3345 0.0 0
M  V30 129 C 2.1866 -14.9662 0.0 0
M  V30 130 C 2.0408 -16.3754 0.0 0
M  V30 131 C 3.3528 -14.043 0.0 0
M  V30 132 C 3.207 -17.0071 0.0 0
M  V30 133 C 4.519 -14.6746 0.0 0
M  V30 134 C 4.3732 -16.0838 0.0 0
M  V30 135 C 5.5394 -16.7155 0.0 0
M  V30 136 N 6.7056 -15.7923 0.0 0
M  V30 137 C 7.8718 -16.4239 0.0 0
M  V30 138 C 6.5598 -14.0915 0.0 0
M  V30 139 O 7.726 -17.8331 0.0 0
M  V30 140 C 9.038 -15.5007 0.0 0
M  V30 141 C 10.2042 -16.1324 0.0 0
M  V30 142 O 13.6056 -9.7183 0.0 0
M  V30 143 C 13.4599 -8.0176 0.0 0
M  V30 144 N 14.6261 -7.0943 0.0 0
M  V30 145 C 12.0021 -7.0943 0.0 0
M  V30 146 C 15.7923 -7.726 0.0 0
M  V30 147 C 14.4803 -5.3936 0.0 0
M  V30 148 C 10.5444 -7.726 0.0 0
M  V30 149 C 16.9585 -6.8028 0.0 0
M  V30 150 C 18.1247 -7.4345 0.0 0
M  V30 151 C 16.8127 -5.1021 0.0 0
M  V30 152 C 19.2909 -6.5112 0.0 0
M  V30 153 C 20.4571 -7.1429 0.0 0
M  V30 154 C 18.3676 -5.0535 0.0 0
M  V30 155 C 19.9226 -5.0535 0.0 0
M  V30 156 C 21.6233 -6.2197 0.0 0
M  V30 157 N 22.7895 -6.8514 0.0 0
M  V30 158 C 23.9557 -5.9281 0.0 0
M  V30 159 C 22.6437 -8.2605 0.0 0
M  V30 160 O 23.8099 -4.2274 0.0 0
M  V30 161 C 25.1219 -6.5598 0.0 0
M  V30 162 C 26.2881 -5.6366 0.0 0
M  V30 163 O 13.6056 -48.9804 0.0 0
M  V30 164 C 13.4599 -50.3896 0.0 0
M  V30 165 N 14.6261 -51.0213 0.0 0
M  V30 166 C 12.0021 -51.0213 0.0 0
M  V30 167 C 15.7923 -50.098 0.0 0
M  V30 168 C 14.4803 -52.4304 0.0 0
M  V30 169 C 10.5444 -50.098 0.0 0
M  V30 170 C 16.9585 -50.7297 0.0 0
M  V30 171 C 18.1247 -49.8065 0.0 0
M  V30 172 N 19.2909 -50.4381 0.0 0
M  V30 173 C 20.4571 -49.5149 0.0 0
M  V30 174 C 19.1451 -51.8473 0.0 0
M  V30 175 O 20.3113 -47.8142 0.0 0
M  V30 176 C 21.6233 -50.1466 0.0 0
M  V30 177 C 22.7895 -49.2234 0.0 0
M  V30 178 O 6.9972 -6.6084 0.0 0
M  V30 179 C 6.8514 -8.0176 0.0 0
M  V30 180 N 5.3936 -8.6493 0.0 0
M  V30 181 C 8.0176 -8.6493 0.0 0
M  V30 182 C 3.9359 -7.726 0.0 0
M  V30 183 C 9.1838 -7.726 0.0 0
M  V30 184 C 2.4781 -8.3577 0.0 0
M  V30 185 C 3.7901 -6.0253 0.0 0
M  V30 186 C 5.2964 -7.1915 0.0 0
M  V30 187 C 1.0204 -7.4345 0.0 0
M  V30 188 C 1.2633 -9.281 0.0 0
M  V30 189 C 3.4014 -9.281 0.0 0
M  V30 190 C 2.3324 -5.1021 0.0 0
M  V30 191 C 0.8746 -5.7338 0.0 0
M  V30 192 C 2.1866 -3.4014 0.0 0
M  V30 193 N -0.5831 -4.8105 0.0 0
M  V30 194 C -2.0408 -5.4422 0.0 0
M  V30 195 O -2.1866 -6.8514 0.0 0
M  V30 196 C -3.4986 -4.519 0.0 0
M  V30 197 C -4.9563 -5.1507 0.0 0
M  V30 198 O 26.4338 -23.324 0.0 0
M  V30 199 C 24.7331 -23.1782 0.0 0
M  V30 200 N 23.8099 -24.3444 0.0 0
M  V30 201 C 23.8099 -21.7204 0.0 0
M  V30 202 C 24.4416 -25.5106 0.0 0
M  V30 203 C 24.4416 -20.2627 0.0 0
M  V30 204 C 23.5183 -26.6768 0.0 0
M  V30 205 C 24.6845 -27.3085 0.0 0
M  V30 206 C 22.0606 -25.7536 0.0 0
M  V30 207 C 24.15 -27.843 0.0 0
M  V30 208 N 25.8507 -26.3853 0.0 0
M  V30 209 N 20.6028 -26.3853 0.0 0
M  V30 210 N 23.2268 -29.0092 0.0 0
M  V30 211 C 27.0169 -27.0169 0.0 0
M  V30 212 C 19.1451 -25.462 0.0 0
M  V30 213 C 23.8585 -30.1754 0.0 0
M  V30 214 O 26.8712 -28.4261 0.0 0
M  V30 215 C 28.1831 -26.0937 0.0 0
M  V30 216 O 18.9993 -23.7613 0.0 0
M  V30 217 C 17.6873 -26.0937 0.0 0
M  V30 218 O 25.2676 -30.0296 0.0 0
M  V30 219 C 22.9352 -31.3416 0.0 0
M  V30 220 C 29.3493 -26.7254 0.0 0
M  V30 221 C 16.2296 -25.1705 0.0 0
M  V30 222 C 23.5669 -32.5078 0.0 0
M  V30 223 O 5.0535 -39.2621 0.0 0
M  V30 224 C 3.3528 -39.1163 0.0 0
M  V30 225 N 2.4295 -40.2825 0.0 0
M  V30 226 C 2.4295 -37.6585 0.0 0
M  V30 227 C 3.0612 -41.4487 0.0 0
M  V30 228 C 3.0612 -36.2008 0.0 0
M  V30 229 C 2.138 -42.6149 0.0 0
M  V30 230 C 3.3042 -43.2466 0.0 0
M  V30 231 C 0.6802 -41.6916 0.0 0
M  V30 232 C 2.7697 -43.7811 0.0 0
M  V30 233 N 4.4704 -42.3233 0.0 0
M  V30 234 N -0.7774 -42.3233 0.0 0
M  V30 235 C 1.8464 -44.9473 0.0 0
M  V30 236 C 5.6366 -42.955 0.0 0
M  V30 237 C -2.2352 -41.4001 0.0 0
M  V30 238 O 5.4908 -44.3642 0.0 0
M  V30 239 C 6.8028 -42.0318 0.0 0
M  V30 240 O -2.3809 -39.6994 0.0 0
M  V30 241 C -3.6929 -42.0318 0.0 0
M  V30 242 C 7.969 -42.6635 0.0 0
M  V30 243 C -5.1507 -41.1085 0.0 0
M  V30 244 O 14.3831 -38.8733 0.0 0
M  V30 245 C 14.2373 -40.2825 0.0 0
M  V30 246 N 15.4035 -40.9142 0.0 0
M  V30 247 C 12.7796 -40.9142 0.0 0
M  V30 248 C 16.5697 -39.9909 0.0 0
M  V30 249 C 11.3218 -39.9909 0.0 0
M  V30 250 C 17.7359 -40.6226 0.0 0
M  V30 251 C 18.9021 -39.6994 0.0 0
M  V30 252 C 17.5902 -42.0318 0.0 0
M  V30 253 C 20.0683 -40.3311 0.0 0
M  V30 254 C 19.1451 -41.0599 0.0 0
M  V30 255 C 18.7564 -42.6635 0.0 0
M  V30 256 C 19.9226 -41.7402 0.0 0
M  V30 257 C 21.3803 -39.6994 0.0 0
M  V30 258 C 21.2345 -42.0804 0.0 0
M  V30 259 C 22.1578 -40.817 0.0 0
M  V30 260 C 22.4007 -42.7121 0.0 0
M  V30 261 N 23.5669 -41.7888 0.0 0
M  V30 262 C 24.7331 -42.4205 0.0 0
M  V30 263 O 24.5874 -43.8297 0.0 0
M  V30 264 C 25.8993 -41.4973 0.0 0
M  V30 265 C 27.0655 -42.129 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 2 11 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 2 13 17
M  V30 17 2 15 18
M  V30 18 1 15 19
M  V30 19 1 16 20
M  V30 20 2 19 21
M  V30 21 2 20 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 2 23 25
M  V30 25 2 24 26
M  V30 26 2 27 28
M  V30 27 1 28 29
M  V30 28 1 28 30
M  V30 29 1 29 31
M  V30 30 1 29 32
M  V30 31 2 30 33
M  V30 32 1 31 34
M  V30 33 1 32 35
M  V30 34 2 34 36
M  V30 35 1 34 37
M  V30 36 1 35 38
M  V30 37 1 36 39
M  V30 38 2 37 40
M  V30 39 1 38 41
M  V30 40 2 39 42
M  V30 41 1 41 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 45 46
M  V30 45 1 46 47
M  V30 46 1 47 48
M  V30 47 1 48 49
M  V30 48 1 48 50
M  V30 49 2 49 51
M  V30 50 1 49 52
M  V30 51 1 50 53
M  V30 52 2 52 54
M  V30 53 2 53 55
M  V30 54 1 53 56
M  V30 55 1 55 57
M  V30 56 2 56 58
M  V30 57 2 57 59
M  V30 58 2 60 61
M  V30 59 1 61 62
M  V30 60 1 61 63
M  V30 61 1 62 64
M  V30 62 1 62 65
M  V30 63 2 63 66
M  V30 64 1 64 67
M  V30 65 1 65 68
M  V30 66 1 67 69
M  V30 67 1 68 70
M  V30 68 1 69 71
M  V30 69 1 70 72
M  V30 70 1 71 73
M  V30 71 1 71 74
M  V30 72 1 72 75
M  V30 73 1 72 76
M  V30 74 2 73 77
M  V30 75 1 73 78
M  V30 76 2 75 79
M  V30 77 1 75 80
M  V30 78 2 78 81
M  V30 79 2 80 82
M  V30 80 2 83 84
M  V30 81 1 84 85
M  V30 82 1 84 86
M  V30 83 1 85 87
M  V30 84 1 85 88
M  V30 85 2 86 89
M  V30 86 1 87 90
M  V30 87 1 88 91
M  V30 88 1 90 92
M  V30 89 1 90 93
M  V30 90 1 92 94
M  V30 91 1 93 95
M  V30 92 1 94 96
M  V30 93 1 96 97
M  V30 94 1 97 98
M  V30 95 1 98 99
M  V30 96 1 98 100
M  V30 97 2 99 101
M  V30 98 1 99 102
M  V30 99 1 100 103
M  V30 100 2 102 104
M  V30 101 2 105 106
M  V30 102 1 106 107
M  V30 103 1 106 108
M  V30 104 1 107 109
M  V30 105 1 107 110
M  V30 106 2 108 111
M  V30 107 1 109 112
M  V30 108 1 110 113
M  V30 109 1 112 114
M  V30 110 1 114 115
M  V30 111 1 115 116
M  V30 112 1 115 117
M  V30 113 2 116 118
M  V30 114 1 116 119
M  V30 115 1 117 120
M  V30 116 2 119 121
M  V30 117 2 122 123
M  V30 118 1 123 124
M  V30 119 1 123 125
M  V30 120 1 124 126
M  V30 121 1 124 127
M  V30 122 2 125 128
M  V30 123 1 126 129
M  V30 124 2 129 130
M  V30 125 1 129 131
M  V30 126 1 130 132
M  V30 127 2 131 133
M  V30 128 2 132 134
M  V30 129 1 134 135
M  V30 130 1 135 136
M  V30 131 1 136 137
M  V30 132 1 136 138
M  V30 133 2 137 139
M  V30 134 1 137 140
M  V30 135 2 140 141
M  V30 136 2 142 143
M  V30 137 1 143 144
M  V30 138 1 143 145
M  V30 139 1 144 146
M  V30 140 1 144 147
M  V30 141 2 145 148
M  V30 142 1 146 149
M  V30 143 1 149 150
M  V30 144 1 149 151
M  V30 145 1 150 152
M  V30 146 1 152 153
M  V30 147 1 152 154
M  V30 148 1 152 155
M  V30 149 1 153 156
M  V30 150 1 156 157
M  V30 151 1 157 158
M  V30 152 1 157 159
M  V30 153 2 158 160
M  V30 154 1 158 161
M  V30 155 2 161 162
M  V30 156 2 163 164
M  V30 157 1 164 165
M  V30 158 1 164 166
M  V30 159 1 165 167
M  V30 160 1 165 168
M  V30 161 2 166 169
M  V30 162 1 167 170
M  V30 163 1 170 171
M  V30 164 1 171 172
M  V30 165 1 172 173
M  V30 166 1 172 174
M  V30 167 2 173 175
M  V30 168 1 173 176
M  V30 169 2 176 177
M  V30 170 2 178 179
M  V30 171 1 179 180
M  V30 172 1 179 181
M  V30 173 1 180 182
M  V30 174 2 181 183
M  V30 175 1 182 184
M  V30 176 1 182 185
M  V30 177 1 182 186
M  V30 178 1 184 187
M  V30 179 1 184 188
M  V30 180 1 184 189
M  V30 181 1 185 190
M  V30 182 1 187 191
M  V30 183 1 190 192
M  V30 184 1 191 193
M  V30 185 1 193 194
M  V30 186 2 194 195
M  V30 187 1 194 196
M  V30 188 2 196 197
M  V30 189 2 198 199
M  V30 190 1 199 200
M  V30 191 1 199 201
M  V30 192 1 200 202
M  V30 193 2 201 203
M  V30 194 1 202 204
M  V30 195 1 204 205
M  V30 196 1 204 206
M  V30 197 1 204 207
M  V30 198 1 205 208
M  V30 199 1 206 209
M  V30 200 1 207 210
M  V30 201 1 208 211
M  V30 202 1 209 212
M  V30 203 1 210 213
M  V30 204 2 211 214
M  V30 205 1 211 215
M  V30 206 2 212 216
M  V30 207 1 212 217
M  V30 208 1 213 218
M  V30 209 1 213 219
M  V30 210 2 215 220
M  V30 211 2 217 221
M  V30 212 2 219 222
M  V30 213 2 223 224
M  V30 214 1 224 225
M  V30 215 1 224 226
M  V30 216 1 225 227
M  V30 217 2 226 228
M  V30 218 1 227 229
M  V30 219 1 229 230
M  V30 220 1 229 231
M  V30 221 1 229 232
M  V30 222 1 230 233
M  V30 223 1 231 234
M  V30 224 1 232 235
M  V30 225 1 233 236
M  V30 226 1 234 237
M  V30 227 2 236 238
M  V30 228 1 236 239
M  V30 229 2 237 240
M  V30 230 1 237 241
M  V30 231 2 239 242
M  V30 232 2 241 243
M  V30 233 2 244 245
M  V30 234 1 245 246
M  V30 235 1 245 247
M  V30 236 1 246 248
M  V30 237 2 247 249
M  V30 238 1 248 250
M  V30 239 1 250 251
M  V30 240 1 250 252
M  V30 241 1 251 253
M  V30 242 1 251 254
M  V30 243 1 252 255
M  V30 244 1 253 256
M  V30 245 1 253 257
M  V30 246 1 256 258
M  V30 247 1 257 259
M  V30 248 1 258 260
M  V30 249 1 260 261
M  V30 250 1 261 262
M  V30 251 2 262 263
M  V30 252 1 262 264
M  V30 253 2 264 265
M  V30 254 1 14 17
M  V30 255 1 25 26
M  V30 256 1 40 42
M  V30 257 1 58 59
M  V30 258 1 95 96
M  V30 259 1 133 134
M  V30 260 1 190 191
M  V30 261 1 254 255
M  V30 262 1 255 256
M  V30 263 1 258 259
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000721A1-20220106-C00006

>  <Row No>
440

$$$$
US20220000721A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 150 148 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0776 1.5783 0.0 0
M  V30 3 N 1.1384 2.4063 0.0 0
M  V30 4 C -1.4489 2.4063 0.0 0
M  V30 5 C 2.3546 1.7336 0.0 0
M  V30 6 C 1.0608 3.9847 0.0 0
M  V30 7 C -2.8203 1.7336 0.0 0
M  V30 8 C 3.5707 2.5616 0.0 0
M  V30 9 C 2.2769 4.8127 0.0 0
M  V30 10 O 3.493 4.1399 0.0 0
M  V30 11 O -8.9009 0.6209 0.0 0
M  V30 12 C -8.9785 2.1993 0.0 0
M  V30 13 N -7.7624 3.0273 0.0 0
M  V30 14 C -10.3499 3.0273 0.0 0
M  V30 15 C -6.5463 2.3546 0.0 0
M  V30 16 C -7.84 4.6057 0.0 0
M  V30 17 C -11.7212 2.3546 0.0 0
M  V30 18 C -5.3302 3.1825 0.0 0
M  V30 19 C -6.6239 5.4337 0.0 0
M  V30 20 C -5.4078 4.7609 0.0 0
M  V30 21 O 7.8659 0.6209 0.0 0
M  V30 22 C 7.7883 2.1993 0.0 0
M  V30 23 N 9.0044 3.0273 0.0 0
M  V30 24 C 6.4169 3.0273 0.0 0
M  V30 25 C 10.2205 2.3546 0.0 0
M  V30 26 C 8.9267 4.6057 0.0 0
M  V30 27 C 5.0455 2.3546 0.0 0
M  V30 28 C 11.4366 1.6818 0.0 0
M  V30 29 C 10.1429 3.9329 0.0 0
M  V30 30 C 9.3407 0.6209 0.0 0
M  V30 31 C 10.1429 5.4337 0.0 0
M  V30 32 C 12.6527 2.5098 0.0 0
M  V30 33 C 11.359 4.7609 0.0 0
M  V30 34 C 10.6345 1.3196 0.0 0
M  V30 35 C 12.5751 4.0882 0.0 0
M  V30 36 C 11.6953 0.7503 0.0 0
M  V30 37 C 10.5569 3.7 0.0 0
M  V30 38 O -8.9009 13.6618 0.0 0
M  V30 39 C -8.9785 15.2402 0.0 0
M  V30 40 N -7.7624 16.0682 0.0 0
M  V30 41 C -10.3499 16.0682 0.0 0
M  V30 42 C -7.84 17.6465 0.0 0
M  V30 43 C -6.5463 15.3954 0.0 0
M  V30 44 C -11.7212 15.3954 0.0 0
M  V30 45 C -6.6239 18.4745 0.0 0
M  V30 46 C -9.2114 18.4745 0.0 0
M  V30 47 C -5.3302 16.2234 0.0 0
M  V30 48 C -6.7015 20.0529 0.0 0
M  V30 49 C -9.289 20.0529 0.0 0
M  V30 50 C -4.114 15.5507 0.0 0
M  V30 51 C -8.0729 20.8809 0.0 0
M  V30 52 C -2.8979 16.3787 0.0 0
M  V30 53 O -6.2099 26.4957 0.0 0
M  V30 54 C -7.5813 25.823 0.0 0
M  V30 55 N -7.6589 24.3999 0.0 0
M  V30 56 C -8.9526 26.651 0.0 0
M  V30 57 C -6.4428 23.7271 0.0 0
M  V30 58 C -9.0302 23.7271 0.0 0
M  V30 59 C -9.0302 28.2293 0.0 0
M  V30 60 C -5.2267 24.5551 0.0 0
M  V30 61 C -10.4016 24.5551 0.0 0
M  V30 62 C -4.0105 23.8824 0.0 0
M  V30 63 C -11.773 23.8824 0.0 0
M  V30 64 C -2.7944 24.7104 0.0 0
M  V30 65 N -1.5783 24.0376 0.0 0
M  V30 66 C -1.6559 25.616 0.0 0
M  V30 67 C -0.3622 24.8656 0.0 0
M  V30 68 O -3.0273 26.444 0.0 0
M  V30 69 C -0.4398 26.444 0.0 0
M  V30 70 C 0.8538 24.1929 0.0 0
M  V30 71 C -0.5174 28.0223 0.0 0
M  V30 72 C 2.0699 25.0209 0.0 0
M  V30 73 O 2.0699 13.6618 0.0 0
M  V30 74 C 1.9923 15.2402 0.0 0
M  V30 75 N 3.2084 16.0682 0.0 0
M  V30 76 C 0.6209 16.0682 0.0 0
M  V30 77 C 3.1308 17.6465 0.0 0
M  V30 78 C 4.4245 15.3954 0.0 0
M  V30 79 C -0.7503 15.3954 0.0 0
M  V30 80 C 4.3469 18.4745 0.0 0
M  V30 81 C 5.6407 16.2234 0.0 0
M  V30 82 C 5.563 17.8018 0.0 0
M  V30 83 C 4.2693 20.0529 0.0 0
M  V30 84 C 6.8568 15.5507 0.0 0
M  V30 85 C 6.7791 18.6298 0.0 0
M  V30 86 C 5.4854 20.8809 0.0 0
M  V30 87 C 8.0729 16.3787 0.0 0
M  V30 88 C 6.7015 20.2082 0.0 0
M  V30 89 C 9.289 15.7059 0.0 0
M  V30 90 C 10.5051 16.5339 0.0 0
M  V30 91 C 11.7212 15.8612 0.0 0
M  V30 92 O 19.6648 7.8659 0.0 0
M  V30 93 C 19.5872 9.4442 0.0 0
M  V30 94 N 20.8033 10.2722 0.0 0
M  V30 95 C 18.2158 10.2722 0.0 0
M  V30 96 C 22.0194 9.5995 0.0 0
M  V30 97 C 20.7256 11.8506 0.0 0
M  V30 98 C 16.8444 9.5995 0.0 0
M  V30 99 C 23.2355 10.4275 0.0 0
M  V30 100 C 21.9418 12.6786 0.0 0
M  V30 101 O 16.9738 0.6209 0.0 0
M  V30 102 C 16.8962 2.1993 0.0 0
M  V30 103 N 18.1123 3.0273 0.0 0
M  V30 104 C 15.5248 3.0273 0.0 0
M  V30 105 C 19.3284 2.3546 0.0 0 CFG=2
M  V30 106 C 18.0347 4.6057 0.0 0
M  V30 107 C 14.1535 2.3546 0.0 0
M  V30 108 C 20.5445 3.1825 0.0 0
M  V30 109 C 19.2508 0.9314 0.0 0
M  V30 110 C 21.7606 2.5098 0.0 0
M  V30 111 C 20.4669 4.7609 0.0 0
M  V30 112 C 22.9768 3.3378 0.0 0
M  V30 113 C 21.683 5.5889 0.0 0
M  V30 114 C 22.8991 4.9162 0.0 0
M  V30 115 O 7.4519 22.9768 0.0 0
M  V30 116 C 7.3743 24.5551 0.0 0
M  V30 117 N 8.5904 25.3831 0.0 0
M  V30 118 C 6.0029 25.3831 0.0 0
M  V30 119 C 9.8065 24.7104 0.0 0
M  V30 120 C 8.5128 26.9615 0.0 0
M  V30 121 C 4.6315 24.7104 0.0 0
M  V30 122 C 11.0226 25.5384 0.0 0
M  V30 123 C 12.2387 24.8656 0.0 0
M  V30 124 C 13.4548 25.6936 0.0 0
M  V30 125 C 14.6709 25.0209 0.0 0
M  V30 126 C 15.8871 25.8489 0.0 0
M  V30 127 C 17.1032 25.1761 0.0 0
M  V30 128 O -8.9009 7.8659 0.0 0
M  V30 129 C -8.9785 9.4442 0.0 0
M  V30 130 N -7.7624 10.2722 0.0 0
M  V30 131 C -10.3499 10.2722 0.0 0
M  V30 132 C -6.5463 9.5995 0.0 0
M  V30 133 C -11.7212 9.5995 0.0 0
M  V30 134 C -5.3302 10.4275 0.0 0
M  V30 135 C -4.114 9.7547 0.0 0
M  V30 136 C -2.8979 10.5827 0.0 0
M  V30 137 C -1.6818 9.91 0.0 0
M  V30 138 C -0.4657 10.738 0.0 0
M  V30 139 C 0.7503 10.0652 0.0 0
M  V30 140 C 1.9664 10.8932 0.0 0
M  V30 141 C 3.1825 10.2205 0.0 0
M  V30 142 C 4.3987 11.0485 0.0 0
M  V30 143 C 5.6148 10.3757 0.0 0
M  V30 144 C 6.8309 11.2037 0.0 0
M  V30 145 C 8.047 10.531 0.0 0
M  V30 146 C 9.2631 11.359 0.0 0
M  V30 147 C 10.4792 10.6862 0.0 0
M  V30 148 C 11.6953 11.5142 0.0 0
M  V30 149 C 12.9115 10.8415 0.0 0
M  V30 150 C 14.1276 11.6695 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 8 10
M  V30 10 2 11 12
M  V30 11 1 12 13
M  V30 12 1 12 14
M  V30 13 1 13 15
M  V30 14 1 13 16
M  V30 15 2 14 17
M  V30 16 1 15 18
M  V30 17 1 16 19
M  V30 18 1 18 20
M  V30 19 2 21 22
M  V30 20 1 22 23
M  V30 21 1 22 24
M  V30 22 1 23 25
M  V30 23 1 23 26
M  V30 24 2 24 27
M  V30 25 1 25 28
M  V30 26 1 25 29
M  V30 27 1 25 30
M  V30 28 1 26 31
M  V30 29 1 28 32
M  V30 30 1 29 33
M  V30 31 1 30 34
M  V30 32 1 32 35
M  V30 33 1 32 36
M  V30 34 1 33 37
M  V30 35 2 38 39
M  V30 36 1 39 40
M  V30 37 1 39 41
M  V30 38 1 40 42
M  V30 39 1 40 43
M  V30 40 2 41 44
M  V30 41 1 42 45
M  V30 42 1 42 46
M  V30 43 1 43 47
M  V30 44 1 45 48
M  V30 45 1 46 49
M  V30 46 1 47 50
M  V30 47 1 48 51
M  V30 48 1 50 52
M  V30 49 2 53 54
M  V30 50 1 54 55
M  V30 51 1 54 56
M  V30 52 1 55 57
M  V30 53 1 55 58
M  V30 54 2 56 59
M  V30 55 1 57 60
M  V30 56 1 58 61
M  V30 57 2 60 62
M  V30 58 2 61 63
M  V30 59 1 62 64
M  V30 60 1 64 65
M  V30 61 1 65 66
M  V30 62 1 65 67
M  V30 63 2 66 68
M  V30 64 1 66 69
M  V30 65 1 67 70
M  V30 66 2 69 71
M  V30 67 2 70 72
M  V30 68 2 73 74
M  V30 69 1 74 75
M  V30 70 1 74 76
M  V30 71 1 75 77
M  V30 72 1 75 78
M  V30 73 2 76 79
M  V30 74 1 77 80
M  V30 75 1 78 81
M  V30 76 2 80 82
M  V30 77 1 80 83
M  V30 78 1 81 84
M  V30 79 1 82 85
M  V30 80 2 83 86
M  V30 81 1 84 87
M  V30 82 2 85 88
M  V30 83 1 87 89
M  V30 84 1 89 90
M  V30 85 1 90 91
M  V30 86 2 92 93
M  V30 87 1 93 94
M  V30 88 1 93 95
M  V30 89 1 94 96
M  V30 90 1 94 97
M  V30 91 2 95 98
M  V30 92 1 96 99
M  V30 93 1 97 100
M  V30 94 2 101 102
M  V30 95 1 102 103
M  V30 96 1 102 104
M  V30 97 1 103 105
M  V30 98 1 103 106
M  V30 99 2 104 107
M  V30 100 1 105 108
M  V30 101 1 105 109 CFG=3
M  V30 102 2 108 110
M  V30 103 1 108 111
M  V30 104 1 110 112
M  V30 105 2 111 113
M  V30 106 2 112 114
M  V30 107 2 115 116
M  V30 108 1 116 117
M  V30 109 1 116 118
M  V30 110 1 117 119
M  V30 111 1 117 120
M  V30 112 2 118 121
M  V30 113 1 119 122
M  V30 114 1 122 123
M  V30 115 1 123 124
M  V30 116 1 124 125
M  V30 117 1 125 126
M  V30 118 1 126 127
M  V30 119 2 128 129
M  V30 120 1 129 130
M  V30 121 1 129 131
M  V30 122 1 130 132
M  V30 123 2 131 133
M  V30 124 1 132 134
M  V30 125 1 134 135
M  V30 126 1 135 136
M  V30 127 1 136 137
M  V30 128 1 137 138
M  V30 129 1 138 139
M  V30 130 1 139 140
M  V30 131 1 140 141
M  V30 132 1 141 142
M  V30 133 1 142 143
M  V30 134 1 143 144
M  V30 135 1 144 145
M  V30 136 1 145 146
M  V30 137 1 146 147
M  V30 138 1 147 148
M  V30 139 1 148 149
M  V30 140 1 149 150
M  V30 141 1 9 10
M  V30 142 1 19 20
M  V30 143 1 33 35
M  V30 144 1 34 36
M  V30 145 1 34 37
M  V30 146 1 49 51
M  V30 147 1 86 88
M  V30 148 1 113 114
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 105)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00026002.cdx

>  <name>
US20220000721A1-20220106-C00007

>  <Row No>
441

$$$$
US20220000721A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 19 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3358 -0.722 0.0 0
M  V30 3 N -1.3719 -2.1903 0.0 0
M  V30 4 C -2.6716 0.0481 0.0 0
M  V30 5 C -0.1083 -2.9123 0.0 0
M  V30 6 C -2.7077 -2.9123 0.0 0
M  V30 7 C -2.7077 1.5885 0.0 0
M  V30 8 C 1.1553 -2.1421 0.0 0
M  V30 9 C -4.0436 -2.1421 0.0 0
M  V30 10 C 2.4189 -2.8642 0.0 0
M  V30 11 C -5.3794 -2.8642 0.0 0
M  V30 12 C 3.6826 -2.094 0.0 0
M  V30 13 N 4.9462 -2.8161 0.0 0
M  V30 14 C 4.9101 -1.2756 0.0 0
M  V30 15 C 6.2098 -2.0338 0.0 0
M  V30 16 O 3.5742 -0.5054 0.0 0
M  V30 17 C 6.1737 -0.5054 0.0 0
M  V30 18 C 7.4735 -2.7559 0.0 0
M  V30 19 C 6.1376 1.0349 0.0 0
M  V30 20 C 8.7371 -1.9857 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 2 8 10
M  V30 10 2 9 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 2 17 19
M  V30 19 2 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000721A1-20220106-C00008

>  <Row No>
442

$$$$
US20220000721A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 17 16 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0365 -1.4874 0.0 0
M  V30 3 N 1.2435 -2.2189 0.0 0
M  V30 4 C -1.3898 -2.2189 0.0 0
M  V30 5 C 2.5237 -1.4264 0.0 0
M  V30 6 C 1.2069 -3.7063 0.0 0
M  V30 7 C -2.7431 -1.4264 0.0 0
M  V30 8 C 3.8038 -2.1579 0.0 0
M  V30 9 C 2.4871 -4.4378 0.0 0
M  V30 10 C 5.084 -1.3654 0.0 0
M  V30 11 N 6.3641 -2.097 0.0 0
M  V30 12 C 7.6443 -1.3045 0.0 0
M  V30 13 C 6.3275 -3.5844 0.0 0
M  V30 14 O 7.6077 0.256 0.0 0
M  V30 15 C 8.9244 -2.036 0.0 0
M  V30 16 C 7.6077 -4.3159 0.0 0
M  V30 17 C 10.2046 -1.2435 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 8 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 13 2 12 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 2 15 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000721A1-20220106-C00009

>  <Row No>
443

$$$$
US20220000721A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 7 6 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Y 0.0 0.0 0.0 0 VAL=1
M  V30 2 O 2.0669 0.0492 0.0 0
M  V30 3 P 3.0184 -0.9022 0.0 0
M  V30 4 O 3.9699 0.1476 0.0 0
M  V30 5 O 3.9699 -1.8537 0.0 0
M  V30 6 O 1.9521 -1.8537 0.0 0
M  V30 7 Y 5.3643 -1.8045 0.0 0 VAL=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 2 3 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 5 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000721A1-20220106-C00010

>  <Row No>
444

$$$$
US20220000721A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0153 -1.4577 0.0 0
M  V30 3 O 1.2122 -2.1329 0.0 0
M  V30 4 C -1.3043 -2.1636 0.0 0
M  V30 5 C 3.1457 -2.0869 0.0 0
M  V30 6 C -1.3503 -3.5907 0.0 0
M  V30 7 ? -2.5933 -1.427 0.0 0
M  V30 8 C 4.5728 -2.0408 0.0 0
M  V30 9 O -0.3682 6.3835 0.0 0
M  V30 10 C -0.3836 4.9257 0.0 0
M  V30 11 N 0.8439 4.2505 0.0 0
M  V30 12 C -1.6726 4.2198 0.0 0
M  V30 13 C 2.7774 4.2965 0.0 0
M  V30 14 C 0.7979 2.8234 0.0 0 RAD=2
M  V30 15 C -1.7186 2.7927 0.0 0
M  V30 16 ? -2.9615 4.9564 0.0 0
M  V30 17 C 4.2045 4.3426 0.0 0
M  V30 18 O 0.7365 9.8207 0.0 0
M  V30 19 C -0.5831 9.1456 0.0 0
M  V30 20 C 2.1636 9.8668 0.0 0
M  V30 21 C -1.9027 9.9128 0.0 0
M  V30 22 C 3.5907 9.9128 0.0 0
M  V30 23 C -1.9488 11.432 0.0 0
M  V30 24 C -3.2224 9.2376 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 2 9 10
M  V30 9 1 10 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 1 11 14
M  V30 13 2 12 15
M  V30 14 1 12 16
M  V30 15 1 13 17
M  V30 16 1 18 19
M  V30 17 1 18 20
M  V30 18 1 19 21
M  V30 19 1 20 22
M  V30 20 2 21 23
M  V30 21 1 21 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000721A1-20220106-C00011

>  <Row No>
445

$$$$
US20220000721A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 6 5 0 0 0
M  V30 BEGIN ATOM
M  V30 1 P 0.0 0.0 0.0 0
M  V30 2 O -0.0444 1.4667 0.0 0
M  V30 3 O 1.3778 0.0444 0.0 0
M  V30 4 O -0.0444 -1.3778 0.0 0
M  V30 5 C -1.8963 0.0444 0.0 0
M  V30 6 C -3.2742 0.0888 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000721A1-20220106-C00012

>  <Row No>
446

$$$$
US20220000721A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 18 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0463 -1.4366 0.0 0
M  V30 3 O 1.1894 -2.1162 0.0 0
M  V30 4 C -1.3748 -2.1162 0.0 0
M  V30 5 C 3.1358 -2.0699 0.0 0
M  V30 6 C -1.4211 -3.5528 0.0 0
M  V30 7 C -2.7032 -1.3439 0.0 0
M  V30 8 O -0.3707 6.4261 0.0 0
M  V30 9 C -0.417 4.9895 0.0 0
M  V30 10 N 0.8187 4.3098 0.0 0
M  V30 11 C -1.7455 4.3098 0.0 0
M  V30 12 C 2.5488 4.3561 0.0 0
M  V30 13 C 0.7723 2.8732 0.0 0
M  V30 14 C -1.7918 2.8732 0.0 0
M  V30 15 C -3.074 5.0821 0.0 0
M  V30 16 O 0.7414 10.0099 0.0 0
M  V30 17 C -0.587 9.3302 0.0 0
M  V30 18 C 1.9463 10.0562 0.0 0
M  V30 19 C -1.9154 10.1025 0.0 0
M  V30 20 C -1.9618 11.6318 0.0 0
M  V30 21 C -3.2439 9.4229 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 2 8 9
M  V30 8 1 9 10
M  V30 9 1 9 11
M  V30 10 1 10 12
M  V30 11 1 10 13
M  V30 12 2 11 14
M  V30 13 1 11 15
M  V30 14 1 16 17
M  V30 15 1 16 18
M  V30 16 1 17 19
M  V30 17 2 19 20
M  V30 18 1 19 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000721A1-20220106-C00013

>  <Row No>
447

$$$$
US20220000721A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 102 98 0 0 0
M  V30 BEGIN ATOM
M  V30 1 P 0.0 0.0 0.0 0
M  V30 2 O -1.3694 -0.6549 0.0 0
M  V30 3 O -1.3694 0.8335 0.0 0
M  V30 4 O 1.1908 0.8335 0.0 0
M  V30 5 O 1.1908 -0.6549 0.0 0
M  V30 6 C -2.7389 0.1786 0.0 0
M  V30 7 O -4.1084 1.0122 0.0 0
M  V30 8 C -5.4779 0.3572 0.0 0
M  V30 9 C -6.8474 1.1908 0.0 0
M  V30 10 C -6.9367 2.7687 0.0 0
M  V30 11 C -8.2169 0.5358 0.0 0
M  V30 12 P -2.6198 12.8612 0.0 0
M  V30 13 O -3.9893 12.2062 0.0 0
M  V30 14 O -1.9649 11.6703 0.0 0
M  V30 15 O -3.4534 14.2307 0.0 0
M  V30 16 O -1.429 13.6948 0.0 0
M  V30 17 C -2.7985 10.4795 0.0 0
M  V30 18 C -2.1435 9.2886 0.0 0
M  V30 19 C -2.9771 8.0978 0.0 0
M  V30 20 C -3.513 10.1222 0.0 0
M  V30 21 C -0.9526 8.6337 0.0 0
M  V30 22 O -2.3221 6.9069 0.0 0
M  V30 23 O -4.8825 9.4673 0.0 0
M  V30 24 O 0.2381 9.4673 0.0 0
M  V30 25 P -3.1557 5.7161 0.0 0
M  V30 26 C -6.2519 10.3009 0.0 0
M  V30 27 C 1.429 8.8123 0.0 0
M  V30 28 O -4.5252 6.5497 0.0 0
M  V30 29 O -3.9893 4.5252 0.0 0
M  V30 30 O -1.9649 5.0611 0.0 0
M  V30 31 C -7.6214 9.6459 0.0 0
M  V30 32 C 2.6198 9.6459 0.0 0
M  V30 33 C -7.7107 8.2466 0.0 0
M  V30 34 C -8.9909 10.4795 0.0 0
M  V30 35 C 2.5305 11.2238 0.0 0
M  V30 36 C 3.8107 8.9909 0.0 0
M  V30 37 P -2.6198 16.1956 0.0 0
M  V30 38 O -3.9893 17.0292 0.0 0
M  V30 39 O -1.9649 17.5651 0.0 0
M  V30 40 O -3.4534 15.0047 0.0 0
M  V30 41 O -1.429 15.5406 0.0 0
M  V30 42 C -2.7985 18.9346 0.0 0
M  V30 43 C -2.1435 20.304 0.0 0
M  V30 44 C -3.513 21.1376 0.0 0
M  V30 45 C -2.9771 21.6735 0.0 0
M  V30 46 C -0.9526 19.6491 0.0 0
M  V30 47 O -4.8825 20.4827 0.0 0
M  V30 48 O -2.3221 23.043 0.0 0
M  V30 49 O 0.2381 20.4827 0.0 0
M  V30 50 C -6.2519 21.3163 0.0 0
M  V30 51 C -3.1557 24.4125 0.0 0
M  V30 52 C 1.429 19.8277 0.0 0
M  V30 53 C -7.6214 20.6613 0.0 0
M  V30 54 C -2.5007 25.782 0.0 0
M  V30 55 C 2.6198 20.6613 0.0 0
M  V30 56 C -7.7107 19.262 0.0 0
M  V30 57 C -8.9909 21.4949 0.0 0
M  V30 58 C -1.1015 25.8713 0.0 0
M  V30 59 C -3.3343 27.1515 0.0 0
M  V30 60 C 2.5305 22.2392 0.0 0
M  V30 61 C 3.8107 20.0063 0.0 0
M  V30 62 P 1.429 30.4859 0.0 0
M  V30 63 O 0.0595 31.3195 0.0 0
M  V30 64 O 2.0839 31.8553 0.0 0
M  V30 65 O 0.5954 29.295 0.0 0
M  V30 66 O 2.6198 29.8309 0.0 0
M  V30 67 C 1.2503 33.2248 0.0 0
M  V30 68 C 1.9053 34.5943 0.0 0
M  V30 69 C 3.0962 33.9393 0.0 0
M  V30 70 C 2.5603 35.9638 0.0 0
M  V30 71 C 0.5358 33.9393 0.0 0
M  V30 72 O 4.287 34.7729 0.0 0
M  V30 73 O 1.7267 37.3333 0.0 0
M  V30 74 O -0.8335 34.7729 0.0 0
M  V30 75 C 5.4779 34.118 0.0 0
M  V30 76 C 2.3817 38.7028 0.0 0
M  V30 77 C -2.203 34.118 0.0 0
M  V30 78 C 6.6687 34.9516 0.0 0
M  V30 79 C 1.5481 40.0722 0.0 0
M  V30 80 C -3.5725 34.9516 0.0 0
M  V30 81 C 6.5794 36.5295 0.0 0
M  V30 82 C 7.8596 34.2966 0.0 0
M  V30 83 C -0.0297 40.1616 0.0 0
M  V30 84 C 2.203 41.4417 0.0 0
M  V30 85 C -4.942 34.2966 0.0 0
M  V30 86 C -2.9175 36.3211 0.0 0
M  V30 87 C -4.4061 33.7607 0.0 0
M  V30 88 O -6.3115 35.1302 0.0 0
M  V30 89 O -3.7511 37.6905 0.0 0
M  V30 90 O -3.7511 32.5699 0.0 0
M  V30 91 C -7.681 34.4752 0.0 0
M  V30 92 C -3.0962 39.06 0.0 0
M  V30 93 C -4.5847 31.379 0.0 0
M  V30 94 C -9.0505 35.3088 0.0 0
M  V30 95 C -3.9298 40.4295 0.0 0
M  V30 96 C -3.9298 30.1881 0.0 0
M  V30 97 C -9.1398 36.8867 0.0 0
M  V30 98 C -10.4199 34.6539 0.0 0
M  V30 99 C -5.5077 40.5188 0.0 0
M  V30 100 C -3.2748 41.799 0.0 0
M  V30 101 C -2.5305 30.2775 0.0 0
M  V30 102 C -4.7634 28.9973 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 3 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 2 12 13
M  V30 12 1 12 14
M  V30 13 1 12 15
M  V30 14 1 12 16
M  V30 15 1 14 17
M  V30 16 1 17 18
M  V30 17 1 18 19
M  V30 18 1 18 20
M  V30 19 1 18 21
M  V30 20 1 19 22
M  V30 21 1 20 23
M  V30 22 1 21 24
M  V30 23 1 22 25
M  V30 24 1 23 26
M  V30 25 1 24 27
M  V30 26 2 25 28
M  V30 27 1 25 29
M  V30 28 1 25 30
M  V30 29 1 26 31
M  V30 30 1 27 32
M  V30 31 2 31 33
M  V30 32 1 31 34
M  V30 33 2 32 35
M  V30 34 1 32 36
M  V30 35 2 37 38
M  V30 36 1 37 39
M  V30 37 1 37 40
M  V30 38 1 37 41
M  V30 39 1 39 42
M  V30 40 1 42 43
M  V30 41 1 43 44
M  V30 42 1 43 45
M  V30 43 1 43 46
M  V30 44 1 44 47
M  V30 45 1 45 48
M  V30 46 1 46 49
M  V30 47 1 47 50
M  V30 48 1 48 51
M  V30 49 1 49 52
M  V30 50 1 50 53
M  V30 51 1 51 54
M  V30 52 1 52 55
M  V30 53 2 53 56
M  V30 54 1 53 57
M  V30 55 2 54 58
M  V30 56 1 54 59
M  V30 57 2 55 60
M  V30 58 1 55 61
M  V30 59 2 62 63
M  V30 60 1 62 64
M  V30 61 1 62 65
M  V30 62 1 62 66
M  V30 63 1 64 67
M  V30 64 1 67 68
M  V30 65 1 68 69
M  V30 66 1 68 70
M  V30 67 1 68 71
M  V30 68 1 69 72
M  V30 69 1 70 73
M  V30 70 1 71 74
M  V30 71 1 72 75
M  V30 72 1 73 76
M  V30 73 1 74 77
M  V30 74 1 75 78
M  V30 75 1 76 79
M  V30 76 1 77 80
M  V30 77 2 78 81
M  V30 78 1 78 82
M  V30 79 2 79 83
M  V30 80 1 79 84
M  V30 81 1 80 85
M  V30 82 1 80 86
M  V30 83 1 80 87
M  V30 84 1 85 88
M  V30 85 1 86 89
M  V30 86 1 87 90
M  V30 87 1 88 91
M  V30 88 1 89 92
M  V30 89 1 90 93
M  V30 90 1 91 94
M  V30 91 1 92 95
M  V30 92 1 93 96
M  V30 93 2 94 97
M  V30 94 1 94 98
M  V30 95 2 95 99
M  V30 96 1 95 100
M  V30 97 2 96 101
M  V30 98 1 96 102
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000721A1-20220106-C00014

>  <Row No>
448

$$$$
US20220000721A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=5
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000721A1-20220106-C00015

>  <Row No>
449

$$$$
US20220000721A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=7
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000721A1-20220106-C00017

>  <Row No>
450

$$$$
US20220000721A1-20220106-C00018
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 42 42 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0384 1.5235 0.0 0
M  V30 3 N -1.357 2.3173 0.0 0
M  V30 4 C 1.2034 2.3173 0.0 0
M  V30 5 C -2.6757 1.6003 0.0 0
M  V30 6 C 2.4453 1.6003 0.0 0
M  V30 7 C -3.9944 2.3941 0.0 0
M  V30 8 C -5.3131 1.6771 0.0 0
M  V30 9 C -4.0328 3.9176 0.0 0
M  V30 10 O -5.3515 0.2304 0.0 0
M  V30 11 C -6.6318 2.4709 0.0 0
M  V30 12 C -5.3515 4.7114 0.0 0
M  V30 13 C -6.6702 3.9944 0.0 0
M  V30 14 C -7.9505 1.7539 0.0 0
M  V30 15 C -5.3899 6.2349 0.0 0
M  V30 16 N -7.9889 0.3072 0.0 0
M  V30 17 C -4.1481 7.0287 0.0 0
M  V30 18 C -9.3076 -0.4096 0.0 0
M  V30 19 C -2.9062 7.8225 0.0 0
M  V30 20 C -4.9418 8.3474 0.0 0
M  V30 21 C -3.4311 5.7868 0.0 0
M  V30 22 O -10.6263 0.384 0.0 0
M  V30 23 C -9.346 -1.8564 0.0 0
M  V30 24 C -10.6647 -2.5733 0.0 0
M  V30 25 O -5.2235 13.11 0.0 0
M  V30 26 C -5.2619 14.6336 0.0 0
M  V30 27 N -6.5806 15.4274 0.0 0
M  V30 28 C -4.02 15.4274 0.0 0
M  V30 29 C -7.8993 14.7104 0.0 0
M  V30 30 C -2.7782 14.7104 0.0 0
M  V30 31 C -9.218 15.5042 0.0 0
M  V30 32 C -10.5367 14.7872 0.0 0
M  V30 33 C -9.2564 17.0277 0.0 0
M  V30 34 O -10.5751 13.3405 0.0 0
M  V30 35 C -11.8554 15.581 0.0 0
M  V30 36 C -10.5751 17.8215 0.0 0
M  V30 37 C -11.8938 17.1045 0.0 0
M  V30 38 C -10.6135 19.345 0.0 0
M  V30 39 C -9.3716 20.1388 0.0 0
M  V30 40 C -8.1297 20.9326 0.0 0
M  V30 41 C -10.1654 21.4575 0.0 0
M  V30 42 C -8.6547 18.8969 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 7 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 8 11
M  V30 11 2 9 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 17 20
M  V30 20 1 17 21
M  V30 21 2 18 22
M  V30 22 1 18 23
M  V30 23 2 23 24
M  V30 24 2 25 26
M  V30 25 1 26 27
M  V30 26 1 26 28
M  V30 27 1 27 29
M  V30 28 2 28 30
M  V30 29 1 29 31
M  V30 30 2 31 32
M  V30 31 1 31 33
M  V30 32 1 32 34
M  V30 33 1 32 35
M  V30 34 2 33 36
M  V30 35 2 35 37
M  V30 36 1 36 38
M  V30 37 1 38 39
M  V30 38 1 39 40
M  V30 39 1 39 41
M  V30 40 1 39 42
M  V30 41 1 12 13
M  V30 42 1 36 37
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000721A1-20220106-C00018

>  <Row No>
451

$$$$
US20220000721A1-20220106-C00019
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=10
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00038001.cdx

>  <name>
US20220000721A1-20220106-C00019

>  <Row No>
452

$$$$
US20220000721A1-20220106-C00020
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=5
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00039001.cdx

>  <name>
US20220000721A1-20220106-C00020

>  <Row No>
453

$$$$
US20220000721A1-20220106-C00021
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=7
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00040001.cdx

>  <name>
US20220000721A1-20220106-C00021

>  <Row No>
454

$$$$
US20220000721A1-20220106-C00022
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=10
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00041001.cdx

>  <name>
US20220000721A1-20220106-C00022

>  <Row No>
455

$$$$
US20220000721A1-20220106-C00023
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=11
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00042001.cdx

>  <name>
US20220000721A1-20220106-C00023

>  <Row No>
456

$$$$
US20220000721A1-20220106-C00024
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 7 5 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -1.5123 0.0354 0.0 0
M  V30 3 C -0.0354 -1.4414 0.0 0
M  V30 4 C -0.0354 1.5123 0.0 0
M  V30 5 C -2.2803 1.3469 0.0 0
M  V30 6 C -3.7926 1.3823 0.0 0
M  V30 7 C -3.4973 1.6068 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 5 6
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00043001.cdx

>  <name>
US20220000721A1-20220106-C00024

>  <Row No>
457

$$$$
US20220000721A1-20220106-C00025
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=9
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00044001.cdx

>  <name>
US20220000721A1-20220106-C00025

>  <Row No>
458

$$$$
US20220000721A1-20220106-C00026
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=11
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00045001.cdx

>  <name>
US20220000721A1-20220106-C00026

>  <Row No>
459

$$$$
US20220000721A1-20220106-C00027
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.7724 1.3397 0.0 0
M  V30 3 C -1.2552 3.6692 0.0 0
M  V30 4 C -2.595 2.945 0.0 0
M  V30 5 C 0.012 2.945 0.0 0
M  V30 6 C -1.2914 5.2141 0.0 0
M  V30 7 C -2.6312 1.4725 0.0 0
M  V30 8 C -0.0241 1.4725 0.0 0
M  V30 9 C -0.0241 5.9986 0.0 0
M  V30 10 C -1.3638 0.7362 0.0 0
M  V30 11 C 1.2431 6.7832 0.0 0
M  V30 12 C -1.1224 7.097 0.0 0
M  V30 13 C 1.0017 4.9727 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 3 4
M  V30 3 1 3 5
M  V30 4 1 3 6
M  V30 5 1 4 7
M  V30 6 2 5 8
M  V30 7 1 6 9
M  V30 8 2 7 10
M  V30 9 1 9 11
M  V30 10 1 9 12
M  V30 11 1 9 13
M  V30 12 1 8 10
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00046001.cdx

>  <name>
US20220000721A1-20220106-C00027

>  <Row No>
460

$$$$
US20220000721A1-20220106-C00028
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=7
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00047001.cdx

>  <name>
US20220000721A1-20220106-C00028

>  <Row No>
461

$$$$
US20220000721A1-20220106-C00029
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 7 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.4591 0.0358 0.0 0
M  V30 3 N 2.1766 -1.2199 0.0 0
M  V30 4 C 2.1766 1.3634 0.0 0
M  V30 5 C 1.3993 -2.4756 0.0 0
M  V30 6 C 1.3993 2.6909 0.0 0
M  V30 7 C -0.1315 -2.4398 0.0 0
M  V30 8 O -0.9089 -1.1122 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 1 7 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00049001.cdx

>  <name>
US20220000721A1-20220106-C00029

>  <Row No>
462

$$$$
US20220000721A1-20220106-C00030
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 7 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.4146 0.0347 0.0 0
M  V30 3 N 2.122 -1.1827 0.0 0
M  V30 4 C 2.122 1.3219 0.0 0
M  V30 5 C 1.3567 -2.4003 0.0 0
M  V30 6 C 1.3567 2.609 0.0 0
M  V30 7 C -0.1275 -2.3655 0.0 0
M  V30 8 O -1.3683 -1.0784 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 1 7 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00050001.cdx

>  <name>
US20220000721A1-20220106-C00030

>  <Row No>
463

$$$$
US20220000721A1-20220106-C00031
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=10
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00051001.cdx

>  <name>
US20220000721A1-20220106-C00031

>  <Row No>
464

$$$$
US20220000721A1-20220106-C00032
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0356 1.5228 0.0 0
M  V30 3 C -1.3563 2.2962 0.0 0
M  V30 4 C 1.2135 2.2962 0.0 0
M  V30 5 C -1.3919 3.819 0.0 0
M  V30 6 C 1.1778 3.819 0.0 0
M  V30 7 C -0.1427 4.5924 0.0 0
M  V30 8 C -0.1784 6.1152 0.0 0
M  V30 9 C 1.0707 6.8886 0.0 0
M  V30 10 C 2.3199 7.6619 0.0 0
M  V30 11 C 0.2974 8.2092 0.0 0
M  V30 12 C 1.7846 5.6393 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 6 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00052001.cdx

>  <name>
US20220000721A1-20220106-C00032

>  <Row No>
465

$$$$
US20220000721A1-20220106-C00033
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 7 6 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.4624 0.0359 0.0 0
M  V30 3 C 2.1936 1.3665 0.0 0
M  V30 4 C 2.1936 -1.2227 0.0 0
M  V30 5 C 1.4025 2.6971 0.0 0
M  V30 6 C 1.4145 -2.4813 0.0 0
M  V30 7 C -0.1198 -2.4454 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 4 6
M  V30 6 1 6 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00053001.cdx

>  <name>
US20220000721A1-20220106-C00033

>  <Row No>
466

$$$$
US20220000721A1-20220106-C00034
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=15
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00055001.cdx

>  <name>
US20220000721A1-20220106-C00034

>  <Row No>
467

$$$$
US20220000721A1-20220106-C00035
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=16
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00056001.cdx

>  <name>
US20220000721A1-20220106-C00035

>  <Row No>
468

$$$$
US20220000721A1-20220106-C00036
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=14
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00057001.cdx

>  <name>
US20220000721A1-20220106-C00036

>  <Row No>
469

$$$$
US20220000721A1-20220106-C00037
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 5 4 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0429 -1.3598 0.0 0
M  V30 3 C -1.4887 -1.3169 0.0 0
M  V30 4 C 1.3169 -1.3169 0.0 0
M  V30 5 ? -3.3209 -1.2883 0.0 0 MASS=17
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00058001.cdx

>  <name>
US20220000721A1-20220106-C00037

>  <Row No>
470

$$$$
US20220000721A1-20220106-C00038
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 1.5319 0.0 0
M  V30 3 C 1.2207 2.3099 0.0 0
M  V30 4 C -1.3644 2.3099 0.0 0
M  V30 5 O 1.1848 3.8418 0.0 0
M  V30 6 C 2.4774 1.5918 0.0 0
M  V30 7 C -2.6928 1.5918 0.0 0
M  V30 8 C -1.4003 3.8418 0.0 0
M  V30 9 C -1.0053 0.8976 0.0 0
M  V30 10 C 3.7341 2.3697 0.0 0
M  V30 11 C 2.4415 3.1237 0.0 0
M  V30 12 C 2.0466 0.1795 0.0 0
M  V30 13 C -4.0213 2.3697 0.0 0
M  V30 14 C -2.7288 0.1316 0.0 0
M  V30 15 C -2.7288 3.1237 0.0 0
M  V30 16 C 4.9908 1.6516 0.0 0
M  V30 17 C 3.6982 0.9096 0.0 0
M  V30 18 C 4.0932 3.8538 0.0 0
M  V30 19 O 8.0427 0.2872 0.0 0
M  V30 20 C 8.0068 1.8192 0.0 0
M  V30 21 C 9.2635 2.5971 0.0 0
M  V30 22 C 6.6783 2.5971 0.0 0
M  V30 23 O 9.2276 4.1291 0.0 0
M  V30 24 C 10.5202 1.879 0.0 0
M  V30 25 C 5.3498 1.879 0.0 0
M  V30 26 C 6.6424 4.1291 0.0 0
M  V30 27 C 7.0374 1.1848 0.0 0
M  V30 28 C 11.7769 2.6569 0.0 0
M  V30 29 C 10.4843 3.411 0.0 0
M  V30 30 C 10.0893 0.4667 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 4 8
M  V30 8 1 4 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 1 7 14
M  V30 14 1 7 15
M  V30 15 1 10 16
M  V30 16 1 10 17
M  V30 17 1 10 18
M  V30 18 2 19 20
M  V30 19 1 20 21
M  V30 20 1 20 22
M  V30 21 2 21 23
M  V30 22 1 21 24
M  V30 23 1 22 25
M  V30 24 1 22 26
M  V30 25 1 22 27
M  V30 26 1 24 28
M  V30 27 1 24 29
M  V30 28 1 24 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00059001.cdx

>  <name>
US20220000721A1-20220106-C00038

>  <Row No>
471

$$$$
US20220000721A1-20220106-C00039
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 179 173 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.1284 1.6267 0.0 0
M  V30 3 O -1.5411 2.4829 0.0 0
M  V30 4 C 1.0274 2.4829 0.0 0
M  V30 5 C -2.9538 1.8836 0.0 0
M  V30 6 O 0.899 4.1097 0.0 0
M  V30 7 C 2.1832 1.8836 0.0 0
M  V30 8 C -4.3665 2.7398 0.0 0
M  V30 9 C -3.0822 0.5137 0.0 0
M  V30 10 C 3.3391 2.7398 0.0 0
M  V30 11 C 1.6695 0.5565 0.0 0
M  V30 12 C 2.0548 3.5103 0.0 0
M  V30 13 C -5.7793 2.1404 0.0 0
M  V30 14 C -4.495 4.3665 0.0 0
M  V30 15 C -4.495 -0.0856 0.0 0
M  V30 16 C -1.9264 -0.0856 0.0 0
M  V30 17 C -5.9077 0.7705 0.0 0
M  V30 18 C -5.9077 5.2227 0.0 0
M  V30 19 C -3.3391 5.2227 0.0 0
M  V30 20 C -2.0548 -1.4555 0.0 0
M  V30 21 C -1.1986 0.5137 0.0 0
M  V30 22 O -1.0274 18.4937 0.0 0
M  V30 23 C -1.1558 20.1205 0.0 0
M  V30 24 O -2.5685 20.9767 0.0 0
M  V30 25 C 0.0 20.9767 0.0 0
M  V30 26 C -3.9812 20.3774 0.0 0
M  V30 27 O -0.1284 22.6035 0.0 0
M  V30 28 C 1.1558 20.3774 0.0 0
M  V30 29 C -5.394 21.2335 0.0 0
M  V30 30 C -4.1097 19.0074 0.0 0
M  V30 31 C 2.3117 21.2335 0.0 0
M  V30 32 C 0.6421 19.0503 0.0 0
M  V30 33 C 1.0274 22.0041 0.0 0
M  V30 34 C -6.8067 20.6342 0.0 0
M  V30 35 C -5.5224 22.8603 0.0 0
M  V30 36 C -5.5224 18.4081 0.0 0
M  V30 37 C -2.9538 18.4081 0.0 0
M  V30 38 C -6.9351 19.2643 0.0 0
M  V30 39 O -2.3973 7.5345 0.0 0
M  V30 40 C -2.5257 9.1612 0.0 0
M  V30 41 O -3.9384 10.0174 0.0 0
M  V30 42 C -1.3699 10.0174 0.0 0
M  V30 43 C -5.3512 9.4181 0.0 0
M  V30 44 O -1.4983 11.6442 0.0 0
M  V30 45 C -0.214 9.4181 0.0 0
M  V30 46 C -6.7639 10.2743 0.0 0
M  V30 47 C -5.4796 8.0482 0.0 0
M  V30 48 C -5.4796 11.0448 0.0 0
M  V30 49 C 0.9418 10.2743 0.0 0
M  V30 50 C -0.3424 11.0448 0.0 0
M  V30 51 C -0.7277 8.091 0.0 0
M  V30 52 C 2.0976 9.6749 0.0 0
M  V30 53 C 0.8133 11.901 0.0 0
M  V30 54 C 0.214 7.1492 0.0 0
M  V30 55 O -2.3973 -6.507 0.0 0
M  V30 56 C -2.5257 -4.8803 0.0 0
M  V30 57 O -3.9384 -4.0241 0.0 0
M  V30 58 C -1.3699 -4.0241 0.0 0
M  V30 59 C -5.3512 -4.6234 0.0 0
M  V30 60 O -1.4983 -2.3973 0.0 0
M  V30 61 C -0.214 -4.6234 0.0 0
M  V30 62 C -6.7639 -3.7672 0.0 0
M  V30 63 C -5.4796 -5.9933 0.0 0
M  V30 64 C -5.4796 -2.9966 0.0 0
M  V30 65 C 0.9418 -3.7672 0.0 0
M  V30 66 C -0.3424 -5.9933 0.0 0
M  V30 67 C -0.3424 -2.9966 0.0 0
M  V30 68 C 2.0976 -4.3665 0.0 0
M  V30 69 C 0.8133 -2.1404 0.0 0
M  V30 70 C -1.7551 -6.5926 0.0 0
M  V30 71 C 0.8133 -6.5926 0.0 0
M  V30 72 C 3.2535 -3.5103 0.0 0
M  V30 73 C 1.9692 -1.2842 0.0 0
M  V30 74 C -1.8836 -7.9625 0.0 0
M  V30 75 C 0.6849 -7.9625 0.0 0
M  V30 76 C 3.1251 -1.8836 0.0 0
M  V30 77 C -0.7277 -8.5619 0.0 0
M  V30 78 O -2.3973 28.4256 0.0 0
M  V30 79 C -2.5257 30.0523 0.0 0
M  V30 80 O -3.9384 30.9085 0.0 0
M  V30 81 C -1.3699 30.9085 0.0 0
M  V30 82 C -5.3512 30.3092 0.0 0
M  V30 83 O -1.4983 32.5353 0.0 0
M  V30 84 C -0.214 30.3092 0.0 0
M  V30 85 C -6.7639 31.1654 0.0 0
M  V30 86 C -5.4796 28.9393 0.0 0
M  V30 87 C -5.4796 31.936 0.0 0
M  V30 88 C 0.9418 31.1654 0.0 0
M  V30 89 C -0.7277 28.9821 0.0 0
M  V30 90 C -0.3424 31.936 0.0 0
M  V30 91 C 2.0976 30.5661 0.0 0
M  V30 92 C 0.8133 32.7922 0.0 0
M  V30 93 C 3.2535 31.4222 0.0 0
M  V30 94 C 1.9692 33.6483 0.0 0
M  V30 95 C 3.1251 33.049 0.0 0
M  V30 96 O -2.3973 43.8371 0.0 0
M  V30 97 C -2.5257 45.4638 0.0 0
M  V30 98 O -3.9384 46.32 0.0 0
M  V30 99 C -1.3699 46.32 0.0 0
M  V30 100 C -5.3512 45.7207 0.0 0
M  V30 101 O -1.4983 47.9468 0.0 0
M  V30 102 C -0.214 45.7207 0.0 0
M  V30 103 C -6.7639 46.5769 0.0 0
M  V30 104 C -5.4796 44.3508 0.0 0
M  V30 105 C -5.4796 47.3474 0.0 0
M  V30 106 C 0.9418 46.5769 0.0 0
M  V30 107 C -0.7277 44.3936 0.0 0
M  V30 108 C -0.3424 47.3474 0.0 0
M  V30 109 C 2.0976 45.9775 0.0 0
M  V30 110 C 0.8133 45.207 0.0 0
M  V30 111 C 1.1986 48.1608 0.0 0
M  V30 112 O -2.3973 33.9052 0.0 0
M  V30 113 C -2.5257 35.532 0.0 0
M  V30 114 O -3.9384 36.3882 0.0 0
M  V30 115 C -1.3699 36.3882 0.0 0
M  V30 116 C -5.3512 35.7888 0.0 0
M  V30 117 O -1.4983 38.0149 0.0 0
M  V30 118 C -0.214 35.7888 0.0 0
M  V30 119 C -6.7639 36.645 0.0 0
M  V30 120 C -5.4796 34.4189 0.0 0
M  V30 121 C -5.4796 37.4156 0.0 0
M  V30 122 C 0.9418 36.645 0.0 0
M  V30 123 C -0.7277 34.4617 0.0 0
M  V30 124 C -0.3424 37.4156 0.0 0
M  V30 125 O -2.3973 12.6716 0.0 0
M  V30 126 C -2.5257 14.2984 0.0 0
M  V30 127 O -3.9384 15.1546 0.0 0
M  V30 128 C -1.3699 15.1546 0.0 0
M  V30 129 C -5.3512 14.5552 0.0 0
M  V30 130 O -1.4983 16.7813 0.0 0
M  V30 131 C -0.214 14.5552 0.0 0
M  V30 132 C -6.7639 15.4114 0.0 0
M  V30 133 C -5.4796 13.1853 0.0 0
M  V30 134 C 0.9418 15.4114 0.0 0
M  V30 135 C -0.7277 13.2281 0.0 0
M  V30 136 C -0.3424 16.182 0.0 0
M  V30 137 C 2.0976 14.8121 0.0 0
M  V30 138 C 1.1986 16.9954 0.0 0
M  V30 139 C 0.8133 14.0415 0.0 0
M  V30 140 O 0.3424 23.2884 0.0 0
M  V30 141 C 0.214 24.9152 0.0 0
M  V30 142 O -1.1986 25.7714 0.0 0
M  V30 143 C 1.3699 25.7714 0.0 0
M  V30 144 C -2.6113 25.172 0.0 0
M  V30 145 O 1.2414 27.3981 0.0 0
M  V30 146 C 2.5257 25.172 0.0 0
M  V30 147 C -4.0241 26.0282 0.0 0
M  V30 148 C 3.6816 26.0282 0.0 0
M  V30 149 C 2.012 23.8449 0.0 0
M  V30 150 C 2.3973 26.7988 0.0 0
M  V30 151 C -5.4368 25.4289 0.0 0
M  V30 152 C -6.8495 26.2851 0.0 0
M  V30 153 O -3.7672 39.0424 0.0 0
M  V30 154 C -3.8956 40.6691 0.0 0
M  V30 155 N -5.3083 41.5253 0.0 0
M  V30 156 C -2.7398 41.5253 0.0 0
M  V30 157 C -6.7211 40.926 0.0 0
M  V30 158 C -5.4368 43.1521 0.0 0
M  V30 159 O -2.8682 43.1521 0.0 0
M  V30 160 C -1.5839 40.926 0.0 0
M  V30 161 C -0.428 41.7822 0.0 0
M  V30 162 C -2.0976 39.5989 0.0 0
M  V30 163 C -1.7123 42.5528 0.0 0
M  V30 164 C 0.7277 41.1829 0.0 0
M  V30 165 C -0.5565 40.4123 0.0 0
M  V30 166 C -0.1712 43.3661 0.0 0
M  V30 167 O 6.507 42.8096 0.0 0
M  V30 168 C 6.3786 41.4397 0.0 0
M  V30 169 C 4.9659 40.8404 0.0 0
M  V30 170 C 7.5345 40.8404 0.0 0
M  V30 171 O 4.8374 39.4705 0.0 0
M  V30 172 C 3.5532 41.6966 0.0 0
M  V30 173 C 8.6903 41.6966 0.0 0
M  V30 174 C 7.0207 39.5133 0.0 0
M  V30 175 C 7.406 42.4671 0.0 0
M  V30 176 C 2.1404 41.0972 0.0 0
M  V30 177 C 9.8462 41.0972 0.0 0
M  V30 178 C 8.5619 40.3267 0.0 0
M  V30 179 C 8.9472 43.2805 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 1 7 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 1 8 13
M  V30 13 1 8 14
M  V30 14 2 9 15
M  V30 15 1 9 16
M  V30 16 2 13 17
M  V30 17 1 14 18
M  V30 18 1 14 19
M  V30 19 1 16 20
M  V30 20 1 16 21
M  V30 21 2 22 23
M  V30 22 1 23 24
M  V30 23 1 23 25
M  V30 24 1 24 26
M  V30 25 2 25 27
M  V30 26 1 25 28
M  V30 27 2 26 29
M  V30 28 1 26 30
M  V30 29 1 28 31
M  V30 30 1 28 32
M  V30 31 1 28 33
M  V30 32 1 29 34
M  V30 33 1 29 35
M  V30 34 2 30 36
M  V30 35 1 30 37
M  V30 36 2 34 38
M  V30 37 2 39 40
M  V30 38 1 40 41
M  V30 39 1 40 42
M  V30 40 1 41 43
M  V30 41 2 42 44
M  V30 42 1 42 45
M  V30 43 1 43 46
M  V30 44 1 43 47
M  V30 45 1 43 48
M  V30 46 1 45 49
M  V30 47 1 45 50
M  V30 48 1 45 51
M  V30 49 1 49 52
M  V30 50 1 50 53
M  V30 51 1 51 54
M  V30 52 2 55 56
M  V30 53 1 56 57
M  V30 54 1 56 58
M  V30 55 1 57 59
M  V30 56 2 58 60
M  V30 57 1 58 61
M  V30 58 1 59 62
M  V30 59 1 59 63
M  V30 60 1 59 64
M  V30 61 1 61 65
M  V30 62 1 61 66
M  V30 63 1 61 67
M  V30 64 2 65 68
M  V30 65 1 65 69
M  V30 66 2 66 70
M  V30 67 1 66 71
M  V30 68 1 68 72
M  V30 69 2 69 73
M  V30 70 1 70 74
M  V30 71 2 71 75
M  V30 72 2 72 76
M  V30 73 2 74 77
M  V30 74 2 78 79
M  V30 75 1 79 80
M  V30 76 1 79 81
M  V30 77 1 80 82
M  V30 78 2 81 83
M  V30 79 1 81 84
M  V30 80 1 82 85
M  V30 81 1 82 86
M  V30 82 1 82 87
M  V30 83 1 84 88
M  V30 84 1 84 89
M  V30 85 1 84 90
M  V30 86 2 88 91
M  V30 87 1 88 92
M  V30 88 1 91 93
M  V30 89 2 92 94
M  V30 90 2 93 95
M  V30 91 2 96 97
M  V30 92 1 97 98
M  V30 93 1 97 99
M  V30 94 1 98 100
M  V30 95 2 99 101
M  V30 96 1 99 102
M  V30 97 1 100 103
M  V30 98 1 100 104
M  V30 99 1 100 105
M  V30 100 1 102 106
M  V30 101 1 102 107
M  V30 102 1 102 108
M  V30 103 1 106 109
M  V30 104 1 106 110
M  V30 105 1 106 111
M  V30 106 2 112 113
M  V30 107 1 113 114
M  V30 108 1 113 115
M  V30 109 1 114 116
M  V30 110 2 115 117
M  V30 111 1 115 118
M  V30 112 1 116 119
M  V30 113 1 116 120
M  V30 114 1 116 121
M  V30 115 1 118 122
M  V30 116 1 118 123
M  V30 117 1 118 124
M  V30 118 2 125 126
M  V30 119 1 126 127
M  V30 120 1 126 128
M  V30 121 1 127 129
M  V30 122 2 128 130
M  V30 123 1 128 131
M  V30 124 1 129 132
M  V30 125 1 129 133
M  V30 126 1 131 134
M  V30 127 1 131 135
M  V30 128 1 131 136
M  V30 129 1 134 137
M  V30 130 1 134 138
M  V30 131 1 134 139
M  V30 132 2 140 141
M  V30 133 1 141 142
M  V30 134 1 141 143
M  V30 135 1 142 144
M  V30 136 2 143 145
M  V30 137 1 143 146
M  V30 138 1 144 147
M  V30 139 1 146 148
M  V30 140 1 146 149
M  V30 141 1 146 150
M  V30 142 1 147 151
M  V30 143 1 151 152
M  V30 144 2 153 154
M  V30 145 1 154 155
M  V30 146 1 154 156
M  V30 147 1 155 157
M  V30 148 1 155 158
M  V30 149 2 156 159
M  V30 150 1 156 160
M  V30 151 1 160 161
M  V30 152 1 160 162
M  V30 153 1 160 163
M  V30 154 1 161 164
M  V30 155 1 161 165
M  V30 156 1 161 166
M  V30 157 2 167 168
M  V30 158 1 168 169
M  V30 159 1 168 170
M  V30 160 2 169 171
M  V30 161 1 169 172
M  V30 162 1 170 173
M  V30 163 1 170 174
M  V30 164 1 170 175
M  V30 165 1 172 176
M  V30 166 1 173 177
M  V30 167 1 173 178
M  V30 168 1 173 179
M  V30 169 1 15 17
M  V30 170 1 36 38
M  V30 171 1 73 76
M  V30 172 1 75 77
M  V30 173 1 94 95
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00061001.cdx

>  <name>
US20220000721A1-20220106-C00039

>  <Row No>
472

$$$$
US20220000721A1-20220106-C00040
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 84 87 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0368 1.5358 0.0 0
M  V30 3 O -1.3761 2.3222 0.0 0
M  V30 4 C 1.2287 2.3222 0.0 0
M  V30 5 C -2.7154 1.5973 0.0 0
M  V30 6 O 1.1918 3.8581 0.0 0
M  V30 7 C 2.4942 1.5973 0.0 0
M  V30 8 C -4.0547 2.3836 0.0 0
M  V30 9 C -2.7523 0.1351 0.0 0
M  V30 10 C 2.4574 3.1332 0.0 0
M  V30 11 C 3.7598 2.3836 0.0 0
M  V30 12 C 2.0642 0.1843 0.0 0
M  V30 13 C -5.394 1.6587 0.0 0
M  V30 14 C -4.0915 3.9195 0.0 0
M  V30 15 C -4.0915 -0.5897 0.0 0
M  V30 16 C -1.4867 -0.5897 0.0 0
M  V30 17 C 1.6587 4.4724 0.0 0
M  V30 18 C 2.8137 4.6199 0.0 0
M  V30 19 C 5.222 2.4205 0.0 0
M  V30 20 C 3.7229 3.9195 0.0 0
M  V30 21 C 2.7891 -1.0812 0.0 0
M  V30 22 C 0.9706 -0.8355 0.0 0
M  V30 23 C -5.4308 0.1965 0.0 0
M  V30 24 C -5.4308 4.7059 0.0 0
M  V30 25 C -2.826 4.7059 0.0 0
M  V30 26 C -1.5235 -2.0519 0.0 0
M  V30 27 C -0.6757 -0.0614 0.0 0
M  V30 28 O 2.3591 -8.3552 0.0 0
M  V30 29 C 2.3222 -6.8193 0.0 0
M  V30 30 O 0.9829 -6.0206 0.0 0
M  V30 31 C 3.5878 -6.0206 0.0 0
M  V30 32 C -0.3563 -6.7456 0.0 0
M  V30 33 O 3.5509 -4.4847 0.0 0
M  V30 34 C 4.8533 -6.7456 0.0 0
M  V30 35 C -1.6956 -5.9469 0.0 0
M  V30 36 C -0.3931 -8.2077 0.0 0
M  V30 37 C 6.1189 -5.9469 0.0 0
M  V30 38 C 4.4233 -8.1586 0.0 0
M  V30 39 C 4.8165 -5.2097 0.0 0
M  V30 40 C -3.0349 -6.6718 0.0 0
M  V30 41 C -1.7324 -8.9327 0.0 0
M  V30 42 C 7.3845 -6.6718 0.0 0
M  V30 43 C 6.0821 -4.411 0.0 0
M  V30 44 C -3.0717 -8.134 0.0 0
M  V30 45 C -4.3741 -5.8855 0.0 0
M  V30 46 C -1.7693 -10.3948 0.0 0
M  V30 47 C 8.6501 -5.8855 0.0 0
M  V30 48 C 7.3476 -3.6246 0.0 0
M  V30 49 C -4.411 -8.8589 0.0 0
M  V30 50 C -5.7134 -5.0868 0.0 0
M  V30 51 C -3.6492 -4.5462 0.0 0
M  V30 52 C -5.1605 -7.151 0.0 0
M  V30 53 C -1.8062 -11.857 0.0 0
M  V30 54 C -0.3071 -10.358 0.0 0
M  V30 55 C -3.3052 -10.358 0.0 0
M  V30 56 C 8.6132 -4.3496 0.0 0
M  V30 57 O -1.671 8.8466 0.0 0
M  V30 58 C -1.7079 10.3825 0.0 0
M  V30 59 O -3.0471 11.1689 0.0 0
M  V30 60 C -0.4423 11.1689 0.0 0
M  V30 61 C -4.3864 10.444 0.0 0
M  V30 62 O -0.4791 12.7048 0.0 0
M  V30 63 C 0.8232 10.444 0.0 0
M  V30 64 C -5.7257 11.2303 0.0 0
M  V30 65 C -4.4233 8.9818 0.0 0
M  V30 66 C -4.4233 11.9798 0.0 0
M  V30 67 C 1.2655 12.0167 0.0 0
M  V30 68 C 0.7863 8.9818 0.0 0
M  V30 69 C 2.2853 10.4808 0.0 0
M  V30 70 C 2.7277 12.0536 0.0 0
M  V30 71 C 0.4791 13.356 0.0 0
M  V30 72 C 2.0519 8.2569 0.0 0
M  V30 73 C -0.5529 8.2569 0.0 0
M  V30 74 C 3.0103 9.2153 0.0 0
M  V30 75 C 3.0103 11.8201 0.0 0
M  V30 76 C 3.4526 13.3929 0.0 0
M  V30 77 C 1.2041 14.6953 0.0 0
M  V30 78 C 2.015 6.7947 0.0 0
M  V30 79 C -0.5897 6.7947 0.0 0
M  V30 80 C 4.4724 9.2521 0.0 0
M  V30 81 C 4.4724 11.857 0.0 0
M  V30 82 C 2.6662 14.7322 0.0 0
M  V30 83 C 0.6757 6.0698 0.0 0
M  V30 84 C 5.1974 10.5914 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 1 7 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 1 8 13
M  V30 13 1 8 14
M  V30 14 2 9 15
M  V30 15 1 9 16
M  V30 16 1 10 17
M  V30 17 1 10 18
M  V30 18 1 11 19
M  V30 19 1 11 20
M  V30 20 1 12 21
M  V30 21 1 12 22
M  V30 22 2 13 23
M  V30 23 1 14 24
M  V30 24 1 14 25
M  V30 25 1 16 26
M  V30 26 1 16 27
M  V30 27 2 28 29
M  V30 28 1 29 30
M  V30 29 1 29 31
M  V30 30 1 30 32
M  V30 31 2 31 33
M  V30 32 1 31 34
M  V30 33 2 32 35
M  V30 34 1 32 36
M  V30 35 1 34 37
M  V30 36 1 34 38
M  V30 37 1 34 39
M  V30 38 1 35 40
M  V30 39 2 36 41
M  V30 40 2 37 42
M  V30 41 1 37 43
M  V30 42 2 40 44
M  V30 43 1 40 45
M  V30 44 1 41 46
M  V30 45 1 42 47
M  V30 46 2 43 48
M  V30 47 1 44 49
M  V30 48 1 45 50
M  V30 49 1 45 51
M  V30 50 1 45 52
M  V30 51 1 46 53
M  V30 52 1 46 54
M  V30 53 1 46 55
M  V30 54 2 47 56
M  V30 55 2 57 58
M  V30 56 1 58 59
M  V30 57 1 58 60
M  V30 58 1 59 61
M  V30 59 2 60 62
M  V30 60 1 60 63
M  V30 61 1 61 64
M  V30 62 1 61 65
M  V30 63 1 61 66
M  V30 64 1 63 67
M  V30 65 1 63 68
M  V30 66 1 63 69
M  V30 67 2 67 70
M  V30 68 1 67 71
M  V30 69 2 68 72
M  V30 70 1 68 73
M  V30 71 2 69 74
M  V30 72 1 69 75
M  V30 73 1 70 76
M  V30 74 2 71 77
M  V30 75 1 72 78
M  V30 76 2 73 79
M  V30 77 1 74 80
M  V30 78 2 75 81
M  V30 79 2 76 82
M  V30 80 2 78 83
M  V30 81 2 80 84
M  V30 82 1 15 23
M  V30 83 1 41 44
M  V30 84 1 48 56
M  V30 85 1 77 82
M  V30 86 1 79 83
M  V30 87 1 81 84
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00061002.cdx

>  <name>
US20220000721A1-20220106-C00040

>  <Row No>
473

$$$$
US20220000721A1-20220106-C00041
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 C -1.3261 0.7646 0.0 0
M  V30 3 C 1.2544 0.7646 0.0 0
M  V30 4 C -0.0358 1.5292 0.0 0
M  V30 5 C -0.4301 -1.4097 0.0 0
M  V30 6 O -1.3619 2.2938 0.0 0
M  V30 7 C -2.6522 0.0477 0.0 0
M  V30 8 C 2.5089 0.0477 0.0 0
M  V30 9 C 1.2186 -0.6929 0.0 0
M  V30 10 C 1.6128 2.246 0.0 0
M  V30 11 O -2.6881 -1.4097 0.0 0
M  V30 12 C -3.9784 0.8243 0.0 0
M  V30 13 C -5.3045 0.1075 0.0 0
M  V30 14 C -4.0142 2.3536 0.0 0
M  V30 15 C -3.62 -0.5854 0.0 0
M  V30 16 C -6.6307 0.884 0.0 0
M  V30 17 C -5.3404 -1.35 0.0 0
M  V30 18 C -5.3404 1.6367 0.0 0
M  V30 19 Si 8.0285 0.2867 0.0 0
M  V30 20 C 6.7024 1.0513 0.0 0
M  V30 21 C 9.283 1.0513 0.0 0
M  V30 22 C 7.9927 1.8159 0.0 0
M  V30 23 C 7.5984 -1.123 0.0 0
M  V30 24 O 6.6665 2.5806 0.0 0
M  V30 25 C 5.3762 0.3345 0.0 0
M  V30 26 O 5.3404 -1.123 0.0 0
M  V30 27 C 4.0501 1.0991 0.0 0
M  V30 28 C 2.7239 0.3823 0.0 0
M  V30 29 C 4.0142 2.6283 0.0 0
M  V30 30 C 4.4085 -0.3106 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 2 2 6
M  V30 6 1 2 7
M  V30 7 1 3 8
M  V30 8 1 3 9
M  V30 9 1 3 10
M  V30 10 2 7 11
M  V30 11 1 7 12
M  V30 12 1 12 13
M  V30 13 1 12 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 1 19 20
M  V30 19 1 19 21
M  V30 20 1 19 22
M  V30 21 1 19 23
M  V30 22 2 20 24
M  V30 23 1 20 25
M  V30 24 2 25 26
M  V30 25 1 25 27
M  V30 26 1 27 28
M  V30 27 1 27 29
M  V30 28 1 27 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00062001.cdx

>  <name>
US20220000721A1-20220106-C00041

>  <Row No>
474

$$$$
US20220000721A1-20220106-C00042
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 209 221 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.5928 1.4327 0.0 0
M  V30 3 C 1.9267 1.5809 0.0 0
M  V30 4 C -0.2964 2.8654 0.0 0
M  V30 5 C 2.5196 3.0136 0.0 0
M  V30 6 C 0.2964 4.2982 0.0 0
M  V30 7 C 3.8535 3.1619 0.0 0
M  V30 8 C 1.6303 4.4464 0.0 0
M  V30 9 Si 5.1874 3.3101 0.0 0
M  V30 10 O 3.7053 1.8279 0.0 0
M  V30 11 C 6.5214 3.4583 0.0 0
M  V30 12 C 5.0392 4.9404 0.0 0
M  V30 13 C 5.0392 1.9761 0.0 0
M  V30 14 Cl -11.4618 3.9523 0.0 0
M  V30 15 C -10.1279 4.1005 0.0 0
M  V30 16 C -9.5351 2.9642 0.0 0
M  V30 17 C -9.5351 5.5333 0.0 0
M  V30 18 C -8.2011 3.1124 0.0 0
M  V30 19 C -8.2011 5.6815 0.0 0
M  V30 20 C -7.6083 4.5452 0.0 0
M  V30 21 C -6.2743 4.6934 0.0 0
M  V30 22 Si -4.9404 4.8416 0.0 0
M  V30 23 O -6.4226 3.3595 0.0 0
M  V30 24 C -3.6065 4.9898 0.0 0
M  V30 25 C -5.0886 6.472 0.0 0
M  V30 26 C -5.0886 3.5077 0.0 0
M  V30 27 Si -2.7666 -32.0142 0.0 0
M  V30 28 C -2.9148 -33.3481 0.0 0
M  V30 29 C -1.4327 -31.866 0.0 0
M  V30 30 C -2.9148 -30.3838 0.0 0
M  V30 31 C -4.397 -31.866 0.0 0
M  V30 32 C -1.7785 -33.941 0.0 0
M  V30 33 C -4.3476 -33.941 0.0 0
M  V30 34 C -0.8398 -30.4333 0.0 0
M  V30 35 C -0.8398 -33.0023 0.0 0
M  V30 36 C -1.7785 -29.4946 0.0 0
M  V30 37 C -4.3476 -29.4946 0.0 0
M  V30 38 O -4.5452 -33.1999 0.0 0
M  V30 39 C -6.0273 -31.7178 0.0 0
M  V30 40 C -1.9267 -35.2749 0.0 0
M  V30 41 C -4.4958 -35.2749 0.0 0
M  V30 42 C 0.494 -30.285 0.0 0
M  V30 43 C 0.494 -32.8541 0.0 0
M  V30 44 C -1.9267 -27.8642 0.0 0
M  V30 45 C -4.4958 -27.8642 0.0 0
M  V30 46 C -6.9166 -32.8541 0.0 0
M  V30 47 C -6.9166 -30.285 0.0 0
M  V30 48 C -3.3595 -35.8678 0.0 0
M  V30 49 C 1.0869 -31.4213 0.0 0
M  V30 50 C -3.3595 -26.9749 0.0 0
M  V30 51 C -8.547 -32.7059 0.0 0
M  V30 52 C -8.547 -30.1368 0.0 0
M  V30 53 C -9.4362 -31.2731 0.0 0
M  V30 54 C -11.0666 -31.1249 0.0 0
M  V30 55 O -11.9559 -32.2612 0.0 0
M  V30 56 Si -5.9285 -21.3428 0.0 0
M  V30 57 C -6.0767 -22.6767 0.0 0
M  V30 58 C -4.5946 -21.1946 0.0 0
M  V30 59 C -6.0767 -19.7124 0.0 0
M  V30 60 C -7.5589 -21.1946 0.0 0
M  V30 61 C -4.9404 -23.2696 0.0 0
M  V30 62 C -7.5095 -23.2696 0.0 0
M  V30 63 C -4.0017 -19.7618 0.0 0
M  V30 64 C -4.0017 -22.3309 0.0 0
M  V30 65 C -4.9404 -18.8231 0.0 0
M  V30 66 C -7.5095 -18.8231 0.0 0
M  V30 67 O -7.7071 -19.5642 0.0 0
M  V30 68 C -9.1892 -21.0464 0.0 0
M  V30 69 C -5.0886 -24.6035 0.0 0
M  V30 70 C -7.6577 -24.6035 0.0 0
M  V30 71 C -2.6678 -19.6136 0.0 0
M  V30 72 C -2.6678 -22.1827 0.0 0
M  V30 73 C -5.0886 -17.1928 0.0 0
M  V30 74 C -7.6577 -17.1928 0.0 0
M  V30 75 C -10.0785 -22.1827 0.0 0
M  V30 76 C -10.0785 -19.6136 0.0 0
M  V30 77 C -6.5214 -25.1964 0.0 0
M  V30 78 C -2.0749 -20.7499 0.0 0
M  V30 79 C -6.5214 -16.3035 0.0 0
M  V30 80 C -11.7089 -22.0344 0.0 0
M  V30 81 C -11.7089 -19.4654 0.0 0
M  V30 82 C -12.5982 -20.6017 0.0 0
M  V30 83 Si -5.9285 -41.4999 0.0 0
M  V30 84 C -6.0767 -42.8338 0.0 0
M  V30 85 C -6.0767 -39.8695 0.0 0
M  V30 86 C -7.5589 -41.3517 0.0 0
M  V30 87 C -4.5946 -41.3517 0.0 0
M  V30 88 C -4.9404 -43.4267 0.0 0
M  V30 89 C -7.5095 -43.4267 0.0 0
M  V30 90 C -4.9404 -38.9803 0.0 0
M  V30 91 C -7.5095 -38.9803 0.0 0
M  V30 92 O -7.7071 -39.7213 0.0 0
M  V30 93 C -9.1892 -41.2035 0.0 0
M  V30 94 O -4.7428 -39.7213 0.0 0
M  V30 95 C -3.1124 -41.2035 0.0 0
M  V30 96 C -5.0886 -44.7606 0.0 0
M  V30 97 C -7.6577 -44.7606 0.0 0
M  V30 98 C -5.0886 -37.3499 0.0 0
M  V30 99 C -7.6577 -37.3499 0.0 0
M  V30 100 C -10.0785 -42.3398 0.0 0
M  V30 101 C -10.0785 -39.7707 0.0 0
M  V30 102 C -2.5196 -39.7707 0.0 0
M  V30 103 C -2.5196 -42.3398 0.0 0
M  V30 104 C -6.5214 -45.3535 0.0 0
M  V30 105 C -6.5214 -36.4606 0.0 0
M  V30 106 C -11.7089 -42.1916 0.0 0
M  V30 107 C -11.7089 -39.6225 0.0 0
M  V30 108 C -1.1857 -39.6225 0.0 0
M  V30 109 C -1.1857 -42.1916 0.0 0
M  V30 110 C -12.5982 -40.7588 0.0 0
M  V30 111 C -0.5928 -40.7588 0.0 0
M  V30 112 Si -5.9285 -11.4618 0.0 0
M  V30 113 C -6.0767 -12.7958 0.0 0
M  V30 114 C -4.5946 -11.3136 0.0 0
M  V30 115 C -7.5589 -11.3136 0.0 0
M  V30 116 C -6.0767 -9.8315 0.0 0
M  V30 117 C -4.9404 -13.3886 0.0 0
M  V30 118 C -7.5095 -13.3886 0.0 0
M  V30 119 C -4.0017 -9.8809 0.0 0
M  V30 120 C -4.0017 -12.4499 0.0 0
M  V30 121 O -7.7071 -9.6833 0.0 0
M  V30 122 C -9.1892 -11.1654 0.0 0
M  V30 123 C -5.0886 -14.7226 0.0 0
M  V30 124 C -7.6577 -14.7226 0.0 0
M  V30 125 C -2.6678 -9.7327 0.0 0
M  V30 126 C -2.6678 -12.3017 0.0 0
M  V30 127 C -10.0785 -12.3017 0.0 0
M  V30 128 C -10.0785 -9.7327 0.0 0
M  V30 129 C -6.5214 -15.3154 0.0 0
M  V30 130 C -2.0749 -10.869 0.0 0
M  V30 131 C -11.7089 -12.1535 0.0 0
M  V30 132 C -11.7089 -9.5845 0.0 0
M  V30 133 C -12.5982 -10.7208 0.0 0
M  V30 134 Si -5.9285 -49.7999 0.0 0
M  V30 135 C -7.5589 -49.6517 0.0 0
M  V30 136 C -4.5946 -49.6517 0.0 0
M  V30 137 C -6.0767 -48.1695 0.0 0
M  V30 138 C -6.0767 -51.1338 0.0 0
M  V30 139 O -7.7071 -48.0213 0.0 0
M  V30 140 C -9.1892 -49.5035 0.0 0
M  V30 141 O -4.7428 -48.0213 0.0 0
M  V30 142 C -3.1124 -49.5035 0.0 0
M  V30 143 C -10.0785 -50.6398 0.0 0
M  V30 144 C -10.0785 -48.0707 0.0 0
M  V30 145 C -2.5196 -48.0707 0.0 0
M  V30 146 C -2.5196 -50.6398 0.0 0
M  V30 147 C -11.7089 -50.4916 0.0 0
M  V30 148 C -11.7089 -47.9225 0.0 0
M  V30 149 C -1.1857 -47.9225 0.0 0
M  V30 150 C -1.1857 -50.4916 0.0 0
M  V30 151 C -12.5982 -49.0588 0.0 0
M  V30 152 C -0.5928 -49.0588 0.0 0
M  V30 153 Si -4.7428 -5.5333 0.0 0
M  V30 154 C -6.3732 -5.3851 0.0 0
M  V30 155 C -3.4089 -5.3851 0.0 0
M  V30 156 C -4.891 -3.9029 0.0 0
M  V30 157 C -4.891 -6.8672 0.0 0
M  V30 158 O -6.5214 -6.719 0.0 0
M  V30 159 C -8.0035 -5.2368 0.0 0
M  V30 160 C -8.8928 -6.3732 0.0 0
M  V30 161 C -8.8928 -3.8041 0.0 0
M  V30 162 C -10.5232 -6.2249 0.0 0
M  V30 163 C -10.5232 -3.6559 0.0 0
M  V30 164 N -11.4124 -7.3613 0.0 0 CHG=1
M  V30 165 C -11.4124 -4.7922 0.0 0
M  V30 166 O -13.0428 -7.213 0.0 0
M  V30 167 O -10.8196 -8.4976 0.0 0 CHG=-1
M  V30 168 Si -3.5571 -1.5809 0.0 0
M  V30 169 C -5.1874 -1.4327 0.0 0
M  V30 170 C -2.2232 -1.4327 0.0 0
M  V30 171 C -3.7053 0.0494 0.0 0
M  V30 172 C -3.7053 -2.9148 0.0 0
M  V30 173 O -5.3357 -2.7666 0.0 0
M  V30 174 C -6.8178 -1.2845 0.0 0
M  V30 175 C -7.7071 -2.4208 0.0 0
M  V30 176 C -7.7071 0.1482 0.0 0
M  V30 177 C -9.3374 -2.2726 0.0 0
M  V30 178 C -9.3374 0.2964 0.0 0
M  V30 179 C -10.2267 -0.8398 0.0 0
M  V30 180 N -11.8571 -0.6916 0.0 0 CHG=1
M  V30 181 O -12.7464 0.741 0.0 0
M  V30 182 O -12.7464 -1.8279 0.0 0 CHG=-1
M  V30 183 Si -3.1619 7.9047 0.0 0
M  V30 184 C -4.7922 8.0529 0.0 0
M  V30 185 C -1.8279 8.0529 0.0 0
M  V30 186 C -3.3101 9.5351 0.0 0
M  V30 187 C -3.3101 6.5708 0.0 0
M  V30 188 O -4.9404 6.719 0.0 0
M  V30 189 C -6.4226 8.2011 0.0 0
M  V30 190 C -7.3118 7.0648 0.0 0
M  V30 191 C -7.3118 9.6339 0.0 0
M  V30 192 C -8.9422 7.213 0.0 0
M  V30 193 C -8.9422 9.7821 0.0 0
M  V30 194 C -9.8315 8.6458 0.0 0
M  V30 195 N -11.4618 8.794 0.0 0
M  V30 196 C -12.6476 9.9797 0.0 0
M  V30 197 C -12.6476 7.9047 0.0 0
M  V30 198 Si -5.9285 12.2523 0.0 0
M  V30 199 C -7.5589 12.4005 0.0 0
M  V30 200 C -4.5946 12.4005 0.0 0
M  V30 201 C -6.0767 13.8827 0.0 0
M  V30 202 C -6.0767 10.9184 0.0 0
M  V30 203 O -7.7071 11.0666 0.0 0
M  V30 204 C -9.1892 12.5487 0.0 0
M  V30 205 C -10.0785 11.4124 0.0 0
M  V30 206 C -10.0785 13.9815 0.0 0
M  V30 207 C -11.7089 11.5607 0.0 0
M  V30 208 C -11.7089 14.1297 0.0 0
M  V30 209 C -12.5982 12.9934 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 7 9
M  V30 9 2 7 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 9 13
M  V30 13 1 14 15
M  V30 14 2 15 16
M  V30 15 1 15 17
M  V30 16 1 16 18
M  V30 17 2 17 19
M  V30 18 2 18 20
M  V30 19 1 20 21
M  V30 20 1 21 22
M  V30 21 2 21 23
M  V30 22 1 22 24
M  V30 23 1 22 25
M  V30 24 1 22 26
M  V30 25 1 27 28
M  V30 26 1 27 29
M  V30 27 1 27 30
M  V30 28 1 27 31
M  V30 29 2 28 32
M  V30 30 1 28 33
M  V30 31 2 29 34
M  V30 32 1 29 35
M  V30 33 2 30 36
M  V30 34 1 30 37
M  V30 35 2 31 38
M  V30 36 1 31 39
M  V30 37 1 32 40
M  V30 38 2 33 41
M  V30 39 1 34 42
M  V30 40 2 35 43
M  V30 41 1 36 44
M  V30 42 2 37 45
M  V30 43 2 39 46
M  V30 44 1 39 47
M  V30 45 2 40 48
M  V30 46 2 42 49
M  V30 47 2 44 50
M  V30 48 1 46 51
M  V30 49 2 47 52
M  V30 50 2 51 53
M  V30 51 1 53 54
M  V30 52 1 54 55
M  V30 53 1 56 57
M  V30 54 1 56 58
M  V30 55 1 56 59
M  V30 56 1 56 60
M  V30 57 2 57 61
M  V30 58 1 57 62
M  V30 59 2 58 63
M  V30 60 1 58 64
M  V30 61 2 59 65
M  V30 62 1 59 66
M  V30 63 2 60 67
M  V30 64 1 60 68
M  V30 65 1 61 69
M  V30 66 2 62 70
M  V30 67 1 63 71
M  V30 68 2 64 72
M  V30 69 1 65 73
M  V30 70 2 66 74
M  V30 71 2 68 75
M  V30 72 1 68 76
M  V30 73 2 69 77
M  V30 74 2 71 78
M  V30 75 2 73 79
M  V30 76 1 75 80
M  V30 77 2 76 81
M  V30 78 2 80 82
M  V30 79 1 83 84
M  V30 80 1 83 85
M  V30 81 1 83 86
M  V30 82 1 83 87
M  V30 83 2 84 88
M  V30 84 1 84 89
M  V30 85 2 85 90
M  V30 86 1 85 91
M  V30 87 2 86 92
M  V30 88 1 86 93
M  V30 89 2 87 94
M  V30 90 1 87 95
M  V30 91 1 88 96
M  V30 92 2 89 97
M  V30 93 1 90 98
M  V30 94 2 91 99
M  V30 95 2 93 100
M  V30 96 1 93 101
M  V30 97 2 95 102
M  V30 98 1 95 103
M  V30 99 2 96 104
M  V30 100 2 98 105
M  V30 101 1 100 106
M  V30 102 2 101 107
M  V30 103 1 102 108
M  V30 104 2 103 109
M  V30 105 2 106 110
M  V30 106 2 108 111
M  V30 107 1 112 113
M  V30 108 1 112 114
M  V30 109 1 112 115
M  V30 110 1 112 116
M  V30 111 2 113 117
M  V30 112 1 113 118
M  V30 113 2 114 119
M  V30 114 1 114 120
M  V30 115 2 115 121
M  V30 116 1 115 122
M  V30 117 1 117 123
M  V30 118 2 118 124
M  V30 119 1 119 125
M  V30 120 2 120 126
M  V30 121 2 122 127
M  V30 122 1 122 128
M  V30 123 2 123 129
M  V30 124 2 125 130
M  V30 125 1 127 131
M  V30 126 2 128 132
M  V30 127 2 131 133
M  V30 128 1 134 135
M  V30 129 1 134 136
M  V30 130 1 134 137
M  V30 131 1 134 138
M  V30 132 2 135 139
M  V30 133 1 135 140
M  V30 134 2 136 141
M  V30 135 1 136 142
M  V30 136 2 140 143
M  V30 137 1 140 144
M  V30 138 2 142 145
M  V30 139 1 142 146
M  V30 140 1 143 147
M  V30 141 2 144 148
M  V30 142 1 145 149
M  V30 143 2 146 150
M  V30 144 2 147 151
M  V30 145 2 149 152
M  V30 146 1 153 154
M  V30 147 1 153 155
M  V30 148 1 153 156
M  V30 149 1 153 157
M  V30 150 2 154 158
M  V30 151 1 154 159
M  V30 152 2 159 160
M  V30 153 1 159 161
M  V30 154 1 160 162
M  V30 155 2 161 163
M  V30 156 1 162 164
M  V30 157 2 162 165
M  V30 158 2 164 166
M  V30 159 1 164 167
M  V30 160 1 168 169
M  V30 161 1 168 170
M  V30 162 1 168 171
M  V30 163 1 168 172
M  V30 164 2 169 173
M  V30 165 1 169 174
M  V30 166 2 174 175
M  V30 167 1 174 176
M  V30 168 1 175 177
M  V30 169 2 176 178
M  V30 170 2 177 179
M  V30 171 1 179 180
M  V30 172 2 180 181
M  V30 173 1 180 182
M  V30 174 1 183 184
M  V30 175 1 183 185
M  V30 176 1 183 186
M  V30 177 1 183 187
M  V30 178 2 184 188
M  V30 179 1 184 189
M  V30 180 2 189 190
M  V30 181 1 189 191
M  V30 182 1 190 192
M  V30 183 2 191 193
M  V30 184 2 192 194
M  V30 185 1 194 195
M  V30 186 1 195 196
M  V30 187 1 195 197
M  V30 188 1 198 199
M  V30 189 1 198 200
M  V30 190 1 198 201
M  V30 191 1 198 202
M  V30 192 2 199 203
M  V30 193 1 199 204
M  V30 194 2 204 205
M  V30 195 1 204 206
M  V30 196 1 205 207
M  V30 197 2 206 208
M  V30 198 2 207 209
M  V30 199 1 6 8
M  V30 200 1 19 20
M  V30 201 1 41 48
M  V30 202 1 43 49
M  V30 203 1 45 50
M  V30 204 1 52 53
M  V30 205 1 70 77
M  V30 206 1 72 78
M  V30 207 1 74 79
M  V30 208 1 81 82
M  V30 209 1 97 104
M  V30 210 1 99 105
M  V30 211 1 107 110
M  V30 212 1 109 111
M  V30 213 1 124 129
M  V30 214 1 126 130
M  V30 215 1 132 133
M  V30 216 1 148 151
M  V30 217 1 150 152
M  V30 218 1 163 165
M  V30 219 1 178 179
M  V30 220 1 193 194
M  V30 221 1 208 209
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00064001.cdx

>  <name>
US20220000721A1-20220106-C00042

>  <Row No>
475

$$$$
US20220000721A1-20220106-C00043
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 69 72 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.4645 0.0382 0.0 0
M  V30 3 C 2.1649 -1.2352 0.0 0
M  V30 4 C 2.1649 1.3881 0.0 0
M  V30 5 C 3.6294 -1.197 0.0 0
M  V30 6 C 3.6294 1.4263 0.0 0
M  V30 7 C 4.3298 0.1528 0.0 0
M  V30 8 C 5.7943 0.191 0.0 0
M  V30 9 Si 7.2589 0.2292 0.0 0
M  V30 10 O 5.7561 -1.2734 0.0 0
M  V30 11 C 8.7234 0.2674 0.0 0
M  V30 12 C 7.2207 1.7701 0.0 0
M  V30 13 C 7.2207 -1.2352 0.0 0
M  V30 14 O 8.6852 -1.197 0.0 0
M  V30 15 C 10.328 0.3056 0.0 0
M  V30 16 C 11.0284 1.6555 0.0 0
M  V30 17 C 11.0284 -0.9678 0.0 0
M  V30 18 C 12.4929 1.6937 0.0 0
M  V30 19 C 12.4929 -0.9296 0.0 0
M  V30 20 C 13.1933 0.4202 0.0 0
M  V30 21 Cl 14.6579 0.4584 0.0 0
M  V30 22 Si 7.8447 -10.6973 0.0 0
M  V30 23 C 6.3037 -10.6591 0.0 0
M  V30 24 C 9.3092 -10.6591 0.0 0
M  V30 25 C 7.8065 -9.1564 0.0 0
M  V30 26 C 7.8065 -12.1618 0.0 0
M  V30 27 O 6.2655 -12.1236 0.0 0
M  V30 28 C 4.7628 -10.6209 0.0 0
M  V30 29 O 9.271 -12.1236 0.0 0
M  V30 30 C 10.9138 -10.6209 0.0 0
M  V30 31 C 3.986 -11.8944 0.0 0
M  V30 32 C 3.986 -9.271 0.0 0
M  V30 33 C 11.6142 -9.271 0.0 0
M  V30 34 C 11.6142 -11.8944 0.0 0
M  V30 35 C 2.4451 -11.8562 0.0 0
M  V30 36 C 2.4451 -9.2328 0.0 0
M  V30 37 C 13.0787 -9.2328 0.0 0
M  V30 38 C 13.0787 -11.8562 0.0 0
M  V30 39 C 1.6682 -10.5063 0.0 0
M  V30 40 C 13.7792 -10.5063 0.0 0
M  V30 41 N 0.1273 -10.4681 0.0 0
M  V30 42 N 15.2437 -10.4681 0.0 0
M  V30 43 C -0.9805 -9.3601 0.0 0
M  V30 44 C -0.9805 -11.4996 0.0 0
M  V30 45 C 16.2752 -9.3601 0.0 0
M  V30 46 C 16.2752 -11.4996 0.0 0
M  V30 47 Si 8.1503 -5.0939 0.0 0
M  V30 48 C 9.6148 -5.0557 0.0 0
M  V30 49 C 6.6094 -5.0557 0.0 0
M  V30 50 C 8.1121 -3.553 0.0 0
M  V30 51 C 8.1121 -6.5584 0.0 0
M  V30 52 O 9.5766 -6.5202 0.0 0
M  V30 53 C 11.2194 -5.0175 0.0 0
M  V30 54 O 6.5712 -6.5202 0.0 0
M  V30 55 C 5.0685 -5.0175 0.0 0
M  V30 56 C 11.9199 -3.6676 0.0 0
M  V30 57 C 11.9199 -6.291 0.0 0
M  V30 58 C 4.2916 -6.291 0.0 0
M  V30 59 C 4.2916 -3.6676 0.0 0
M  V30 60 C 13.3844 -3.6294 0.0 0
M  V30 61 C 13.3844 -6.2528 0.0 0
M  V30 62 C 2.7507 -6.2528 0.0 0
M  V30 63 C 2.7507 -3.6294 0.0 0
M  V30 64 C 14.0848 -4.9029 0.0 0
M  V30 65 C 1.9739 -4.9029 0.0 0
M  V30 66 O 15.5493 -4.8647 0.0 0
M  V30 67 C 0.4329 -4.8647 0.0 0
M  V30 68 C 16.2497 -3.5148 0.0 0
M  V30 69 O -0.3438 -6.1382 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 2 8 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 9 13
M  V30 13 2 11 14
M  V30 14 1 11 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 2 18 20
M  V30 20 1 20 21
M  V30 21 1 22 23
M  V30 22 1 22 24
M  V30 23 1 22 25
M  V30 24 1 22 26
M  V30 25 2 23 27
M  V30 26 1 23 28
M  V30 27 2 24 29
M  V30 28 1 24 30
M  V30 29 2 28 31
M  V30 30 1 28 32
M  V30 31 2 30 33
M  V30 32 1 30 34
M  V30 33 1 31 35
M  V30 34 2 32 36
M  V30 35 1 33 37
M  V30 36 2 34 38
M  V30 37 2 35 39
M  V30 38 2 37 40
M  V30 39 1 39 41
M  V30 40 1 40 42
M  V30 41 1 41 43
M  V30 42 1 41 44
M  V30 43 1 42 45
M  V30 44 1 42 46
M  V30 45 1 47 48
M  V30 46 1 47 49
M  V30 47 1 47 50
M  V30 48 1 47 51
M  V30 49 2 48 52
M  V30 50 1 48 53
M  V30 51 2 49 54
M  V30 52 1 49 55
M  V30 53 2 53 56
M  V30 54 1 53 57
M  V30 55 2 55 58
M  V30 56 1 55 59
M  V30 57 1 56 60
M  V30 58 2 57 61
M  V30 59 1 58 62
M  V30 60 2 59 63
M  V30 61 2 60 64
M  V30 62 2 62 65
M  V30 63 1 64 66
M  V30 64 1 65 67
M  V30 65 1 66 68
M  V30 66 1 67 69
M  V30 67 1 6 7
M  V30 68 1 19 20
M  V30 69 1 36 39
M  V30 70 1 38 40
M  V30 71 1 61 64
M  V30 72 1 63 65
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00064002.cdx

>  <name>
US20220000721A1-20220106-C00043

>  <Row No>
476

$$$$
US20220000721A1-20220106-C00044
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 119 119 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.6648 1.3472 0.0 0
M  V30 3 C 2.0996 1.3997 0.0 0
M  V30 4 C -0.1049 2.6945 0.0 0
M  V30 5 C 2.7645 2.747 0.0 0
M  V30 6 C 0.5599 4.0418 0.0 0
M  V30 7 C 4.1993 2.7995 0.0 0
M  V30 8 C 1.9946 4.0943 0.0 0
M  V30 9 Si 5.634 2.852 0.0 0
M  V30 10 O 4.1468 1.3647 0.0 0
M  V30 11 C 5.5816 4.3917 0.0 0
M  V30 12 C 5.5816 1.4172 0.0 0
M  V30 13 C 7.3313 2.9045 0.0 0
M  V30 14 Cl 7.8387 8.5386 0.0 0
M  V30 15 C 9.2735 8.5911 0.0 0
M  V30 16 C 9.9384 9.9384 0.0 0
M  V30 17 C 9.9384 7.3488 0.0 0
M  V30 18 C 11.3731 9.9909 0.0 0
M  V30 19 C 11.3731 7.4013 0.0 0
M  V30 20 C 12.038 8.7486 0.0 0
M  V30 21 C 13.4728 8.801 0.0 0
M  V30 22 Si 14.9076 8.8535 0.0 0
M  V30 23 O 13.4203 7.3663 0.0 0
M  V30 24 C 14.8551 10.3933 0.0 0
M  V30 25 C 14.8551 7.4188 0.0 0
M  V30 26 C 16.6048 8.906 0.0 0
M  V30 27 Si 4.8992 16.2374 0.0 0
M  V30 28 C 6.5964 16.2898 0.0 0
M  V30 29 C 4.8467 14.8026 0.0 0
M  V30 30 C 3.3594 16.2898 0.0 0
M  V30 31 C 4.8467 17.7771 0.0 0
M  V30 32 C 7.2613 15.0475 0.0 0
M  V30 33 C 7.2613 17.6371 0.0 0
M  V30 34 C 3.4994 14.1377 0.0 0
M  V30 35 C 6.089 14.1377 0.0 0
M  V30 36 O 3.3069 17.8296 0.0 0
M  V30 37 C 1.8197 16.3423 0.0 0
M  V30 38 C 8.6961 15.1 0.0 0
M  V30 39 C 8.6961 17.6896 0.0 0
M  V30 40 C 3.4469 12.7029 0.0 0
M  V30 41 C 6.0365 12.7029 0.0 0
M  V30 42 C 1.0498 17.6896 0.0 0
M  V30 43 C 1.0498 15.1 0.0 0
M  V30 44 C 9.361 16.4473 0.0 0
M  V30 45 C 4.6892 12.038 0.0 0
M  V30 46 C -0.4899 17.7421 0.0 0
M  V30 47 C -0.4899 15.1525 0.0 0
M  V30 48 C -1.2597 16.4998 0.0 0
M  V30 49 Si 5.739 -8.2586 0.0 0
M  V30 50 C 4.1993 -8.2061 0.0 0
M  V30 51 C 5.6865 -6.7189 0.0 0
M  V30 52 C 5.6865 -9.6934 0.0 0
M  V30 53 C 7.4363 -8.2061 0.0 0
M  V30 54 O 4.1468 -9.6409 0.0 0
M  V30 55 C 2.6595 -8.1536 0.0 0
M  V30 56 C 1.8896 -9.3959 0.0 0
M  V30 57 C 1.8896 -6.8064 0.0 0
M  V30 58 C 0.3499 -9.3435 0.0 0
M  V30 59 C 0.3499 -6.7539 0.0 0
M  V30 60 N -0.4199 -10.5858 0.0 0 CHG=1
M  V30 61 C -0.4199 -7.9962 0.0 0
M  V30 62 O -1.9596 -10.5333 0.0 0
M  V30 63 O 0.2449 -11.8281 0.0 0 CHG=-1
M  V30 64 Si 7.2788 -2.9395 0.0 0
M  V30 65 C 5.739 -2.887 0.0 0
M  V30 66 C 7.2263 -1.3997 0.0 0
M  V30 67 C 7.2263 -4.3743 0.0 0
M  V30 68 C 8.976 -2.887 0.0 0
M  V30 69 O 5.6865 -4.3218 0.0 0
M  V30 70 C 4.1993 -2.8345 0.0 0
M  V30 71 C 3.4294 -1.4872 0.0 0
M  V30 72 C 3.4294 -4.0768 0.0 0
M  V30 73 C 1.8896 -1.4347 0.0 0
M  V30 74 C 1.8896 -4.0243 0.0 0
M  V30 75 C 1.1198 -2.677 0.0 0
M  V30 76 N -0.4199 -2.6245 0.0 0 CHG=1
M  V30 77 O -1.1898 -1.2772 0.0 0
M  V30 78 O -1.1898 -3.8668 0.0 0 CHG=-1
M  V30 79 Si 4.8992 8.5386 0.0 0
M  V30 80 C 3.3594 8.5911 0.0 0
M  V30 81 C 4.8467 10.0783 0.0 0
M  V30 82 C 4.8467 7.1038 0.0 0
M  V30 83 C 6.5964 8.5911 0.0 0
M  V30 84 O 3.3069 7.1563 0.0 0
M  V30 85 C 1.8197 8.6436 0.0 0
M  V30 86 C 1.0498 9.9909 0.0 0
M  V30 87 C 1.0498 7.4013 0.0 0
M  V30 88 C -0.4899 10.0433 0.0 0
M  V30 89 C -0.4899 7.4538 0.0 0
M  V30 90 C -1.2597 8.801 0.0 0
M  V30 91 O 2.7995 -17.6371 0.0 0
M  V30 92 C 2.747 -16.0974 0.0 0
M  V30 93 O 1.3997 -15.3275 0.0 0
M  V30 94 C 3.9893 -15.3275 0.0 0
M  V30 95 C 0.0524 -15.9924 0.0 0
M  V30 96 O 3.9368 -13.7877 0.0 0
M  V30 97 C 5.2316 -15.9924 0.0 0
M  V30 98 C -1.2947 -15.2225 0.0 0
M  V30 99 C 0.0 -17.4272 0.0 0
M  V30 100 C 0.0 -14.4526 0.0 0
M  V30 101 C 6.4739 -15.2225 0.0 0
M  V30 102 C 5.1791 -14.4526 0.0 0
M  V30 103 C 4.8117 -17.3747 0.0 0
M  V30 104 C 7.7162 -15.8874 0.0 0
M  V30 105 C 6.4214 -16.6573 0.0 0
M  V30 106 C 6.7889 -13.7353 0.0 0
M  V30 107 O 11.3381 -17.6371 0.0 0
M  V30 108 C 11.2856 -16.0974 0.0 0
M  V30 109 N 9.9384 -15.3275 0.0 0
M  V30 110 C 12.5279 -15.3275 0.0 0
M  V30 111 C 8.5911 -15.9924 0.0 0
M  V30 112 C 9.8859 -13.7877 0.0 0
M  V30 113 O 12.4755 -13.7877 0.0 0
M  V30 114 C 13.7702 -15.9924 0.0 0
M  V30 115 C 15.0126 -15.2225 0.0 0
M  V30 116 C 13.7178 -14.4526 0.0 0
M  V30 117 C 13.3503 -17.3747 0.0 0
M  V30 118 C 16.2549 -15.8874 0.0 0
M  V30 119 C 15.3275 -13.7353 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 7 9
M  V30 9 2 7 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 9 13
M  V30 13 1 14 15
M  V30 14 2 15 16
M  V30 15 1 15 17
M  V30 16 1 16 18
M  V30 17 2 17 19
M  V30 18 2 18 20
M  V30 19 1 20 21
M  V30 20 1 21 22
M  V30 21 2 21 23
M  V30 22 1 22 24
M  V30 23 1 22 25
M  V30 24 1 22 26
M  V30 25 1 27 28
M  V30 26 1 27 29
M  V30 27 1 27 30
M  V30 28 1 27 31
M  V30 29 2 28 32
M  V30 30 1 28 33
M  V30 31 2 29 34
M  V30 32 1 29 35
M  V30 33 2 30 36
M  V30 34 1 30 37
M  V30 35 1 32 38
M  V30 36 2 33 39
M  V30 37 1 34 40
M  V30 38 2 35 41
M  V30 39 2 37 42
M  V30 40 1 37 43
M  V30 41 2 38 44
M  V30 42 2 40 45
M  V30 43 1 42 46
M  V30 44 2 43 47
M  V30 45 2 46 48
M  V30 46 1 49 50
M  V30 47 1 49 51
M  V30 48 1 49 52
M  V30 49 1 49 53
M  V30 50 2 50 54
M  V30 51 1 50 55
M  V30 52 2 55 56
M  V30 53 1 55 57
M  V30 54 1 56 58
M  V30 55 2 57 59
M  V30 56 1 58 60
M  V30 57 2 58 61
M  V30 58 2 60 62
M  V30 59 1 60 63
M  V30 60 1 64 65
M  V30 61 1 64 66
M  V30 62 1 64 67
M  V30 63 1 64 68
M  V30 64 2 65 69
M  V30 65 1 65 70
M  V30 66 2 70 71
M  V30 67 1 70 72
M  V30 68 1 71 73
M  V30 69 2 72 74
M  V30 70 2 73 75
M  V30 71 1 75 76
M  V30 72 2 76 77
M  V30 73 1 76 78
M  V30 74 1 79 80
M  V30 75 1 79 81
M  V30 76 1 79 82
M  V30 77 1 79 83
M  V30 78 2 80 84
M  V30 79 1 80 85
M  V30 80 2 85 86
M  V30 81 1 85 87
M  V30 82 1 86 88
M  V30 83 2 87 89
M  V30 84 2 88 90
M  V30 85 2 91 92
M  V30 86 1 92 93
M  V30 87 1 92 94
M  V30 88 1 93 95
M  V30 89 2 94 96
M  V30 90 1 94 97
M  V30 91 1 95 98
M  V30 92 1 95 99
M  V30 93 1 95 100
M  V30 94 1 97 101
M  V30 95 1 97 102
M  V30 96 1 97 103
M  V30 97 1 101 104
M  V30 98 1 101 105
M  V30 99 1 101 106
M  V30 100 2 107 108
M  V30 101 1 108 109
M  V30 102 1 108 110
M  V30 103 1 109 111
M  V30 104 1 109 112
M  V30 105 2 110 113
M  V30 106 1 110 114
M  V30 107 1 114 115
M  V30 108 1 114 116
M  V30 109 1 114 117
M  V30 110 1 115 118
M  V30 111 1 115 119
M  V30 112 1 6 8
M  V30 113 1 19 20
M  V30 114 1 39 44
M  V30 115 1 41 45
M  V30 116 1 47 48
M  V30 117 1 59 61
M  V30 118 1 74 75
M  V30 119 1 89 90
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00065001.cdx

>  <name>
US20220000721A1-20220106-C00044

>  <Row No>
477

$$$$
US20220000721A1-20220106-C00045
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 50 51 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 C 1.7051 0.0429 0.0 0
M  V30 3 C -0.0429 -1.4471 0.0 0
M  V30 4 C -1.5331 0.0429 0.0 0
M  V30 5 C -0.0429 1.5331 0.0 0
M  V30 6 C 2.3928 -1.2036 0.0 0
M  V30 7 C 2.3928 1.3755 0.0 0
M  V30 8 C -1.3755 -2.1349 0.0 0
M  V30 9 C 1.2036 -2.1349 0.0 0
M  V30 10 O -1.5761 1.5761 0.0 0
M  V30 11 C -3.0663 0.0859 0.0 0
M  V30 12 C 3.84 -1.1606 0.0 0
M  V30 13 C 3.84 1.4185 0.0 0
M  V30 14 C -1.4185 -3.5821 0.0 0
M  V30 15 C 1.1606 -3.5821 0.0 0
M  V30 16 C -3.84 1.4185 0.0 0
M  V30 17 C -3.84 -1.1606 0.0 0
M  V30 18 C 4.5278 0.1719 0.0 0
M  V30 19 C -0.1719 -4.2699 0.0 0
M  V30 20 C -5.3732 1.4615 0.0 0
M  V30 21 C -5.3732 -1.1176 0.0 0
M  V30 22 C -6.1469 0.2149 0.0 0
M  V30 23 Si -0.3438 -6.1899 0.0 0
M  V30 24 C -1.877 -6.1469 0.0 0
M  V30 25 C -0.3868 -4.6567 0.0 0
M  V30 26 C -0.3868 -7.6371 0.0 0
M  V30 27 C 1.3612 -6.1469 0.0 0
M  V30 28 O -1.92 -7.5941 0.0 0
M  V30 29 C -3.4102 -6.1039 0.0 0
M  V30 30 C -4.1839 -4.7714 0.0 0
M  V30 31 C -4.1839 -7.3505 0.0 0
M  V30 32 C -5.7171 -4.7284 0.0 0
M  V30 33 C -5.7171 -7.3075 0.0 0
M  V30 34 C -6.4908 -5.975 0.0 0
M  V30 35 O -2.4072 -14.4432 0.0 0
M  V30 36 C -2.4501 -12.91 0.0 0
M  V30 37 O -3.7827 -12.1363 0.0 0
M  V30 38 C -1.2036 -12.1363 0.0 0
M  V30 39 C -5.1153 -12.8241 0.0 0
M  V30 40 O -1.2465 -10.6031 0.0 0
M  V30 41 C 0.0429 -12.8241 0.0 0
M  V30 42 C -6.4478 -12.0503 0.0 0
M  V30 43 C -5.1582 -14.2712 0.0 0
M  V30 44 C -5.1582 -11.2909 0.0 0
M  V30 45 C 1.2895 -12.0503 0.0 0
M  V30 46 C 0.0 -11.2909 0.0 0
M  V30 47 C -0.3725 -14.2139 0.0 0
M  V30 48 C 2.5361 -12.7381 0.0 0
M  V30 49 C 1.2465 -13.4975 0.0 0
M  V30 50 C 1.6191 -10.5745 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 2 2 6
M  V30 6 1 2 7
M  V30 7 2 3 8
M  V30 8 1 3 9
M  V30 9 2 4 10
M  V30 10 1 4 11
M  V30 11 1 6 12
M  V30 12 2 7 13
M  V30 13 1 8 14
M  V30 14 2 9 15
M  V30 15 2 11 16
M  V30 16 1 11 17
M  V30 17 2 12 18
M  V30 18 2 14 19
M  V30 19 1 16 20
M  V30 20 2 17 21
M  V30 21 2 20 22
M  V30 22 1 23 24
M  V30 23 1 23 25
M  V30 24 1 23 26
M  V30 25 1 23 27
M  V30 26 2 24 28
M  V30 27 1 24 29
M  V30 28 2 29 30
M  V30 29 1 29 31
M  V30 30 1 30 32
M  V30 31 2 31 33
M  V30 32 2 32 34
M  V30 33 2 35 36
M  V30 34 1 36 37
M  V30 35 1 36 38
M  V30 36 1 37 39
M  V30 37 2 38 40
M  V30 38 1 38 41
M  V30 39 1 39 42
M  V30 40 1 39 43
M  V30 41 1 39 44
M  V30 42 1 41 45
M  V30 43 1 41 46
M  V30 44 1 41 47
M  V30 45 1 45 48
M  V30 46 1 45 49
M  V30 47 1 45 50
M  V30 48 1 13 18
M  V30 49 1 15 19
M  V30 50 1 21 22
M  V30 51 1 33 34
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00066001.cdx

>  <name>
US20220000721A1-20220106-C00045

>  <Row No>
478

$$$$
US20220000721A1-20220106-C00046
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0 CHG=1
M  V30 2 C -1.5593 0.0365 0.0 0 CHG=-1
M  V30 3 C 1.4862 0.0365 0.0 0
M  V30 4 C 2.2172 -1.2426 0.0 0
M  V30 5 C 2.2172 1.3887 0.0 0
M  V30 6 C 3.7034 -1.206 0.0 0
M  V30 7 C 3.7034 1.4253 0.0 0
M  V30 8 C 4.4465 0.1461 0.0 0
M  V30 9 N 5.9328 0.1827 0.0 0
M  V30 10 C 6.6638 -1.0964 0.0 0
M  V30 11 C 6.6638 1.5349 0.0 0
M  V30 12 C 8.15 -1.0598 0.0 0
M  V30 13 C 8.15 1.5715 0.0 0
M  V30 14 N 8.881 0.2923 0.0 0
M  V30 15 C 10.3672 0.3289 0.0 0
M  V30 16 C 11.1103 -0.9502 0.0 0
M  V30 17 C 11.1103 1.6811 0.0 0
M  V30 18 C 12.5966 -0.9136 0.0 0
M  V30 19 C 12.5966 1.7177 0.0 0
M  V30 20 C 13.3276 0.4385 0.0 0
M  V30 21 C 14.8138 0.4751 0.0 0
M  V30 22 N 16.3001 0.5116 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 3 1 2
M  V30 2 1 1 3
M  V30 3 2 3 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 2 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 2 18 20
M  V30 20 1 20 21
M  V30 21 3 21 22
M  V30 22 1 7 8
M  V30 23 1 13 14
M  V30 24 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00067001.cdx

>  <name>
US20220000721A1-20220106-C00046

>  <Row No>
479

$$$$
US20220000721A1-20220106-C00047
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 19 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3413 0.7733 0.0 0
M  V30 3 C 1.2688 0.7733 0.0 0
M  V30 4 C -2.6826 0.0483 0.0 0
M  V30 5 C 2.5376 0.0483 0.0 0
M  V30 6 O -2.7189 -1.4259 0.0 0
M  V30 7 C -4.0239 0.8337 0.0 0
M  V30 8 C 3.8064 0.8337 0.0 0
M  V30 9 C -5.3653 0.1087 0.0 0
M  V30 10 C 5.0752 0.1087 0.0 0
M  V30 11 C -6.1507 1.45 0.0 0
M  V30 12 C -4.6402 -1.16 0.0 0
M  V30 13 O 6.3441 0.8942 0.0 0
M  V30 14 C 7.6129 0.1691 0.0 0
M  V30 15 C 8.8817 0.9546 0.0 0
M  V30 16 O 8.8455 2.5013 0.0 0
M  V30 17 C 10.1505 0.2295 0.0 0
M  V30 18 C 11.4194 1.015 0.0 0
M  V30 19 C 10.646 2.3563 0.0 0
M  V30 20 C 12.1444 -0.2537 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 15 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00068001.cdx

>  <name>
US20220000721A1-20220106-C00047

>  <Row No>
480

$$$$
US20220000721A1-20220106-C00048
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -1.3324 -0.7078 0.0 0
M  V30 3 C 1.27 -0.7078 0.0 0
M  V30 4 C -2.6649 0.0624 0.0 0
M  V30 5 C 1.9778 0.6245 0.0 0
M  V30 6 C 0.4996 -1.9778 0.0 0
M  V30 7 C -3.9974 -0.6454 0.0 0
M  V30 8 C -4.7677 0.687 0.0 0
M  V30 9 C -3.2895 -1.9154 0.0 0
M  V30 10 C 4.6636 5.9961 0.0 0
M  V30 11 C 5.9336 6.7664 0.0 0
M  V30 12 C 3.3311 6.7664 0.0 0
M  V30 13 C 7.2037 6.0586 0.0 0
M  V30 14 C 1.9987 6.0586 0.0 0
M  V30 15 C 8.4737 6.8289 0.0 0
M  V30 16 C 1.2283 7.391 0.0 0
M  V30 17 C 2.7065 4.7885 0.0 0
M  V30 18 C 7.7033 8.1614 0.0 0
M  V30 19 C 9.1815 5.5589 0.0 0
M  V30 20 C -0.2498 6.5791 0.0 0
M  V30 21 C -1.5823 5.8712 0.0 0
M  V30 22 C -1.0201 7.9115 0.0 0
M  V30 23 C 0.458 5.309 0.0 0
M  V30 24 C -2.9147 6.6415 0.0 0
M  V30 25 C -4.2472 5.9336 0.0 0
M  V30 26 C -5.0176 7.2661 0.0 0
M  V30 27 C -3.5393 4.6636 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 2 10 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 1 12 14
M  V30 13 1 13 15
M  V30 14 1 14 16
M  V30 15 1 14 17
M  V30 16 1 15 18
M  V30 17 1 15 19
M  V30 18 1 20 21
M  V30 19 1 20 22
M  V30 20 1 20 23
M  V30 21 1 21 24
M  V30 22 1 24 25
M  V30 23 1 25 26
M  V30 24 1 25 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00069001.cdx

>  <name>
US20220000721A1-20220106-C00048

>  <Row No>
481

$$$$
US20220000721A1-20220106-C00049
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 9 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2473 0.7603 0.0 0
M  V30 3 C -1.3186 0.7603 0.0 0
M  V30 4 C 1.2117 2.2809 0.0 0
M  V30 5 C -1.3543 2.2809 0.0 0
M  V30 6 N -0.1069 3.0412 0.0 0
M  V30 7 C -0.1425 4.5618 0.0 0
M  V30 8 C -1.6631 4.5975 0.0 0
M  V30 9 C 1.3067 4.5975 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 5 6
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00070001.cdx

>  <name>
US20220000721A1-20220106-C00049

>  <Row No>
482

$$$$
US20220000721A1-20220106-C00050
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00072001.cdx

>  <name>
US20220000721A1-20220106-C00050

>  <Row No>
483

$$$$
US20220000721A1-20220106-C00051
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 270 276 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.9239 -1.167 0.0 0
M  V30 3 O 0.0 -2.091 0.0 0
M  V30 4 C -2.5773 -1.0212 0.0 0
M  V30 5 C 1.167 -2.7232 0.0 0
M  V30 6 C -3.5012 -2.1883 0.0 0
M  V30 7 C -3.5012 0.4376 0.0 0
M  V30 8 C 2.3341 -1.7992 0.0 0
M  V30 9 C -5.1546 -2.0424 0.0 0
M  V30 10 C -5.1546 0.5835 0.0 0
M  V30 11 C 3.5012 -2.4314 0.0 0
M  V30 12 C -6.0786 -0.5835 0.0 0
M  V30 13 N -7.732 -0.4376 0.0 0
M  V30 14 C -8.6559 1.0212 0.0 0
M  V30 15 C -8.6559 -1.6047 0.0 0
M  V30 16 O -2.3341 30.3445 0.0 0
M  V30 17 C -2.48 28.9828 0.0 0
M  V30 18 O -1.3129 28.3507 0.0 0
M  V30 19 C -3.9389 28.3507 0.0 0
M  V30 20 C -0.1458 29.2746 0.0 0
M  V30 21 C -4.0848 26.989 0.0 0
M  V30 22 C -5.3978 29.2746 0.0 0
M  V30 23 C 1.0212 28.6424 0.0 0
M  V30 24 C -5.5437 26.3569 0.0 0
M  V30 25 C -6.8566 28.6424 0.0 0
M  V30 26 O 0.8753 27.2808 0.0 0
M  V30 27 C 2.1883 29.5664 0.0 0
M  V30 28 C -7.0025 27.2808 0.0 0
M  V30 29 O 3.3554 28.9342 0.0 0
M  V30 30 N -8.4614 26.6486 0.0 0
M  V30 31 C 4.5224 29.8582 0.0 0
M  V30 32 C -9.9203 27.5726 0.0 0
M  V30 33 C -8.6073 25.287 0.0 0
M  V30 34 C 5.6895 29.226 0.0 0
M  V30 35 C 6.8566 30.1499 0.0 0
M  V30 36 C 8.0237 29.5178 0.0 0
M  V30 37 O 9.1908 30.4417 0.0 0
M  V30 38 C 10.3579 29.8095 0.0 0
M  V30 39 C 11.525 30.7335 0.0 0
M  V30 40 O 11.3791 32.3869 0.0 0
M  V30 41 C 12.6921 30.1013 0.0 0
M  V30 42 O 13.8592 31.0253 0.0 0
M  V30 43 C 15.0263 30.3931 0.0 0
M  V30 44 O 14.8804 29.0315 0.0 0
M  V30 45 C 16.1934 31.317 0.0 0
M  V30 46 C 17.3605 30.6849 0.0 0
M  V30 47 C 16.0475 32.9704 0.0 0
M  V30 48 C 18.5276 31.6088 0.0 0
M  V30 49 C 17.2146 33.8944 0.0 0
M  V30 50 C 18.3817 33.2622 0.0 0
M  V30 51 N 19.5488 34.1861 0.0 0
M  V30 52 C 20.7159 33.554 0.0 0
M  V30 53 C 19.4029 35.8395 0.0 0
M  V30 54 O -2.3341 49.7961 0.0 0
M  V30 55 C -2.48 48.4344 0.0 0
M  V30 56 O -1.3129 47.8023 0.0 0
M  V30 57 C -3.9389 47.8023 0.0 0
M  V30 58 C -0.1458 48.7262 0.0 0
M  V30 59 C -4.0848 46.4407 0.0 0
M  V30 60 C -5.3978 48.7262 0.0 0
M  V30 61 C 1.0212 48.094 0.0 0
M  V30 62 C -5.5437 45.8085 0.0 0
M  V30 63 C -6.8566 48.094 0.0 0
M  V30 64 O 2.1883 49.018 0.0 0
M  V30 65 C -7.0025 46.7324 0.0 0
M  V30 66 C 3.3554 48.3858 0.0 0
M  V30 67 N -8.4614 46.1002 0.0 0
M  V30 68 O 3.2095 47.0242 0.0 0
M  V30 69 C 4.5224 49.3098 0.0 0
M  V30 70 C -9.9203 47.0242 0.0 0
M  V30 71 C -8.6073 44.7386 0.0 0
M  V30 72 C 5.6895 48.6776 0.0 0
M  V30 73 C 4.3766 50.9631 0.0 0
M  V30 74 C 6.8566 49.6015 0.0 0
M  V30 75 C 5.5437 51.8871 0.0 0
M  V30 76 C 6.7108 51.2549 0.0 0
M  V30 77 N 7.8778 52.1789 0.0 0
M  V30 78 C 9.0449 51.5467 0.0 0
M  V30 79 C 8.121 53.7836 0.0 0
M  V30 80 O 21.3967 19.4516 0.0 0
M  V30 81 C 20.4728 18.2845 0.0 0
M  V30 82 O 21.3967 17.3605 0.0 0
M  V30 83 C 18.8194 18.4303 0.0 0
M  V30 84 C 22.5638 16.7283 0.0 0
M  V30 85 C 17.8954 17.2632 0.0 0
M  V30 86 C 17.8954 19.8892 0.0 0
M  V30 87 C 23.7309 17.6523 0.0 0
M  V30 88 C 16.242 17.4091 0.0 0
M  V30 89 C 16.242 20.0351 0.0 0
M  V30 90 O 24.898 17.0201 0.0 0
M  V30 91 C 15.3181 18.868 0.0 0
M  V30 92 C 26.0651 17.9441 0.0 0
M  V30 93 N 13.6647 19.0139 0.0 0
M  V30 94 O 25.9192 19.5974 0.0 0
M  V30 95 C 27.2322 17.3119 0.0 0
M  V30 96 C 12.7407 20.4728 0.0 0
M  V30 97 C 12.7407 17.8468 0.0 0
M  V30 98 C 28.3993 18.2358 0.0 0
M  V30 99 C 27.0863 15.9503 0.0 0
M  V30 100 O -4.6683 12.838 0.0 0
M  V30 101 C -4.8142 14.4914 0.0 0
M  V30 102 O -6.2731 15.4153 0.0 0
M  V30 103 C -3.6471 15.4153 0.0 0
M  V30 104 C -7.732 14.7832 0.0 0
M  V30 105 C -3.793 17.0687 0.0 0
M  V30 106 C -2.48 14.7832 0.0 0
M  V30 107 C -9.1908 15.7071 0.0 0
M  V30 108 C -2.6259 17.9927 0.0 0
M  V30 109 C -1.3129 15.7071 0.0 0
M  V30 110 C -1.4588 17.3605 0.0 0
M  V30 111 N -0.2917 18.2845 0.0 0
M  V30 112 C 0.8753 17.6523 0.0 0
M  V30 113 C -0.4376 19.9378 0.0 0
M  V30 114 C 2.0424 18.5762 0.0 0
M  V30 115 C 0.7294 20.8618 0.0 0
M  V30 116 N 1.8965 20.2296 0.0 0
M  V30 117 C 3.0636 21.1536 0.0 0
M  V30 118 C 4.2307 20.5214 0.0 0
M  V30 119 C 2.9177 22.807 0.0 0
M  V30 120 C 5.3978 21.4453 0.0 0
M  V30 121 C 4.0848 23.7309 0.0 0
M  V30 122 C 5.2519 23.0987 0.0 0
M  V30 123 C 6.419 24.0227 0.0 0
M  V30 124 O 6.2731 25.6761 0.0 0
M  V30 125 O 7.5861 23.3905 0.0 0
M  V30 126 C 8.7532 24.3145 0.0 0
M  V30 127 C 9.9203 23.6823 0.0 0
M  V30 128 O -2.3341 -6.2245 0.0 0
M  V30 129 C -2.48 -7.5861 0.0 0
M  V30 130 N -1.3129 -8.2183 0.0 0
M  V30 131 C -3.9389 -8.2183 0.0 0
M  V30 132 C -0.1458 -7.2943 0.0 0
M  V30 133 C -1.4588 -9.5799 0.0 0
M  V30 134 C -4.0848 -9.5799 0.0 0
M  V30 135 C -5.3978 -7.2943 0.0 0
M  V30 136 C 1.0212 -7.9265 0.0 0
M  V30 137 C -0.2917 -10.212 0.0 0
M  V30 138 C -5.5437 -10.212 0.0 0
M  V30 139 C -6.8566 -7.9265 0.0 0
M  V30 140 C 2.1883 -7.0025 0.0 0
M  V30 141 C -0.4376 -11.5737 0.0 0
M  V30 142 C -7.0025 -9.2881 0.0 0
M  V30 143 C 3.3554 -7.6347 0.0 0
M  V30 144 N -8.4614 -9.9203 0.0 0
M  V30 145 N 4.5224 -6.7108 0.0 0
M  V30 146 C -9.9203 -8.9963 0.0 0
M  V30 147 C -8.6073 -11.2819 0.0 0
M  V30 148 C 5.6895 -7.3429 0.0 0
M  V30 149 C 4.3766 -5.0574 0.0 0
M  V30 150 O 5.5437 -8.7045 0.0 0
M  V30 151 C 6.8566 -6.419 0.0 0
M  V30 152 C 2.9177 -4.1334 0.0 0
M  V30 153 C 8.0237 -7.0512 0.0 0
M  V30 154 C 6.7108 -4.7656 0.0 0
M  V30 155 C 2.7718 -2.48 0.0 0
M  V30 156 C 9.1908 -6.1272 0.0 0
M  V30 157 C 7.8778 -3.8416 0.0 0
M  V30 158 C 9.0449 -4.4738 0.0 0
M  V30 159 N 10.212 -3.5499 0.0 0
M  V30 160 C 11.3791 -4.182 0.0 0
M  V30 161 C 10.4552 -1.9451 0.0 0
M  V30 162 O 15.1722 8.9477 0.0 0
M  V30 163 C 15.0263 7.5861 0.0 0
M  V30 164 N 16.1934 6.9539 0.0 0
M  V30 165 C 13.5674 6.9539 0.0 0
M  V30 166 C 17.3605 7.8778 0.0 0
M  V30 167 C 16.0475 5.5923 0.0 0
M  V30 168 C 13.4216 5.5923 0.0 0
M  V30 169 C 12.1086 7.8778 0.0 0
M  V30 170 C 18.5276 7.2457 0.0 0
M  V30 171 C 17.2146 4.9601 0.0 0
M  V30 172 C 11.9627 4.9601 0.0 0
M  V30 173 C 10.6497 7.2457 0.0 0
M  V30 174 C 19.6947 8.1696 0.0 0
M  V30 175 C 17.0687 3.5985 0.0 0
M  V30 176 C 10.5038 5.8841 0.0 0
M  V30 177 C 20.8618 7.5374 0.0 0
M  V30 178 N 9.0449 5.2519 0.0 0
M  V30 179 N 22.0289 8.4614 0.0 0
M  V30 180 C 7.5861 6.1758 0.0 0
M  V30 181 C 8.8991 3.8903 0.0 0
M  V30 182 C 23.196 7.8292 0.0 0
M  V30 183 C 21.883 10.1148 0.0 0
M  V30 184 O 23.0501 6.4676 0.0 0
M  V30 185 C 24.3631 8.7532 0.0 0
M  V30 186 C 20.4241 11.0387 0.0 0
M  V30 187 C 25.5302 8.121 0.0 0
M  V30 188 C 20.2782 12.6921 0.0 0
M  V30 189 O 21.3967 -6.2245 0.0 0
M  V30 190 C 21.2508 -7.5861 0.0 0
M  V30 191 N 22.4179 -8.2183 0.0 0
M  V30 192 C 19.792 -8.2183 0.0 0
M  V30 193 C 23.585 -7.2943 0.0 0
M  V30 194 C 22.272 -9.5799 0.0 0
M  V30 195 C 19.6461 -9.5799 0.0 0
M  V30 196 C 18.3331 -7.2943 0.0 0
M  V30 197 C 24.7521 -7.9265 0.0 0
M  V30 198 C 23.4391 -10.212 0.0 0
M  V30 199 C 18.1872 -10.212 0.0 0
M  V30 200 C 16.8742 -7.9265 0.0 0
M  V30 201 C 25.9192 -7.0025 0.0 0
M  V30 202 C 23.2932 -11.5737 0.0 0
M  V30 203 C 16.7283 -9.2881 0.0 0
M  V30 204 N 15.2695 -9.9203 0.0 0
M  V30 205 C 13.8106 -8.9963 0.0 0
M  V30 206 C 15.1236 -11.2819 0.0 0
M  V30 207 O -1.167 7.7806 0.0 0
M  V30 208 C -2.091 6.6135 0.0 0
M  V30 209 N -1.167 5.6895 0.0 0
M  V30 210 C -3.7444 6.7594 0.0 0
M  V30 211 C 0.0 5.0574 0.0 0
M  V30 212 C -4.6683 5.5923 0.0 0
M  V30 213 C -4.6683 8.2183 0.0 0
M  V30 214 C 1.167 5.9813 0.0 0
M  V30 215 C -6.3217 5.7382 0.0 0
M  V30 216 C -6.3217 8.3641 0.0 0
M  V30 217 O 2.3341 5.3491 0.0 0
M  V30 218 C -7.2457 7.197 0.0 0
M  V30 219 C 3.5012 6.2731 0.0 0
M  V30 220 N -8.8991 7.3429 0.0 0
M  V30 221 O 3.3554 7.9265 0.0 0
M  V30 222 C 4.6683 5.6409 0.0 0
M  V30 223 C -9.823 8.8018 0.0 0
M  V30 224 C -9.823 6.1758 0.0 0
M  V30 225 C 5.8354 6.5649 0.0 0
M  V30 226 C 4.5224 4.2793 0.0 0
M  V30 227 O -2.3341 40.0703 0.0 0
M  V30 228 C -2.48 38.7086 0.0 0
M  V30 229 N -1.3129 38.0765 0.0 0
M  V30 230 C -3.9389 38.0765 0.0 0
M  V30 231 C -0.1458 39.0004 0.0 0
M  V30 232 C -4.0848 36.7149 0.0 0
M  V30 233 C -5.3978 39.0004 0.0 0
M  V30 234 C 1.0212 38.3682 0.0 0
M  V30 235 C -5.5437 36.0827 0.0 0
M  V30 236 C -6.8566 38.3682 0.0 0
M  V30 237 N 2.1883 39.2922 0.0 0
M  V30 238 C -7.0025 37.0066 0.0 0
M  V30 239 C 3.3554 38.66 0.0 0
M  V30 240 N -8.4614 36.3744 0.0 0
M  V30 241 O 3.2095 37.2984 0.0 0
M  V30 242 C 4.5224 39.584 0.0 0
M  V30 243 C -9.9203 37.2984 0.0 0
M  V30 244 C -8.6073 35.0128 0.0 0
M  V30 245 C 5.6895 38.9518 0.0 0
M  V30 246 C 4.3766 41.2373 0.0 0
M  V30 247 C 6.8566 39.8757 0.0 0
M  V30 248 C 5.5437 42.1613 0.0 0
M  V30 249 C 6.7108 41.5291 0.0 0
M  V30 250 N 7.8778 42.4531 0.0 0
M  V30 251 C 9.0449 41.8209 0.0 0
M  V30 252 C 7.732 44.1065 0.0 0
M  V30 253 O 12.0599 0.778 0.0 0
M  V30 254 C 11.136 -0.389 0.0 0
M  V30 255 N 12.0599 -1.3129 0.0 0
M  V30 256 C 9.4826 -0.2431 0.0 0
M  V30 257 C 13.227 -1.9451 0.0 0
M  V30 258 C 8.5587 -1.4102 0.0 0
M  V30 259 C 8.5587 1.2157 0.0 0
M  V30 260 C 14.3941 -1.0212 0.0 0
M  V30 261 C 6.9053 -1.2643 0.0 0
M  V30 262 C 6.9053 1.3616 0.0 0
M  V30 263 C 15.5612 -1.6533 0.0 0
M  V30 264 C 5.9813 0.1945 0.0 0
M  V30 265 O 16.7283 -0.7294 0.0 0
M  V30 266 N 4.3279 0.3404 0.0 0
M  V30 267 C 17.8954 -1.3616 0.0 0
M  V30 268 C 3.404 1.7992 0.0 0
M  V30 269 C 3.404 -0.8266 0.0 0
M  V30 270 C 19.0625 -0.4376 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 2 7 10
M  V30 10 2 8 11
M  V30 11 2 9 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 15 2 16 17
M  V30 16 1 17 18
M  V30 17 1 17 19
M  V30 18 1 18 20
M  V30 19 2 19 21
M  V30 20 1 19 22
M  V30 21 1 20 23
M  V30 22 1 21 24
M  V30 23 2 22 25
M  V30 24 1 23 26
M  V30 25 1 23 27
M  V30 26 2 24 28
M  V30 27 1 27 29
M  V30 28 1 28 30
M  V30 29 1 29 31
M  V30 30 1 30 32
M  V30 31 1 30 33
M  V30 32 1 31 34
M  V30 33 1 34 35
M  V30 34 1 35 36
M  V30 35 1 36 37
M  V30 36 1 37 38
M  V30 37 1 38 39
M  V30 38 1 39 40
M  V30 39 1 39 41
M  V30 40 1 41 42
M  V30 41 1 42 43
M  V30 42 2 43 44
M  V30 43 1 43 45
M  V30 44 2 45 46
M  V30 45 1 45 47
M  V30 46 1 46 48
M  V30 47 2 47 49
M  V30 48 2 48 50
M  V30 49 1 50 51
M  V30 50 1 51 52
M  V30 51 1 51 53
M  V30 52 2 54 55
M  V30 53 1 55 56
M  V30 54 1 55 57
M  V30 55 1 56 58
M  V30 56 2 57 59
M  V30 57 1 57 60
M  V30 58 1 58 61
M  V30 59 1 59 62
M  V30 60 2 60 63
M  V30 61 1 61 64
M  V30 62 2 62 65
M  V30 63 1 64 66
M  V30 64 1 65 67
M  V30 65 2 66 68
M  V30 66 1 66 69
M  V30 67 1 67 70
M  V30 68 1 67 71
M  V30 69 2 69 72
M  V30 70 1 69 73
M  V30 71 1 72 74
M  V30 72 2 73 75
M  V30 73 2 74 76
M  V30 74 1 76 77
M  V30 75 1 77 78
M  V30 76 1 77 79
M  V30 77 2 80 81
M  V30 78 1 81 82
M  V30 79 1 81 83
M  V30 80 1 82 84
M  V30 81 2 83 85
M  V30 82 1 83 86
M  V30 83 1 84 87
M  V30 84 1 85 88
M  V30 85 2 86 89
M  V30 86 1 87 90
M  V30 87 2 88 91
M  V30 88 1 90 92
M  V30 89 1 91 93
M  V30 90 2 92 94
M  V30 91 1 92 95
M  V30 92 1 93 96
M  V30 93 1 93 97
M  V30 94 2 95 98
M  V30 95 1 95 99
M  V30 96 2 100 101
M  V30 97 1 101 102
M  V30 98 1 101 103
M  V30 99 1 102 104
M  V30 100 2 103 105
M  V30 101 1 103 106
M  V30 102 1 104 107
M  V30 103 1 105 108
M  V30 104 2 106 109
M  V30 105 2 108 110
M  V30 106 1 110 111
M  V30 107 1 111 112
M  V30 108 1 111 113
M  V30 109 1 112 114
M  V30 110 1 113 115
M  V30 111 1 114 116
M  V30 112 1 116 117
M  V30 113 2 117 118
M  V30 114 1 117 119
M  V30 115 1 118 120
M  V30 116 2 119 121
M  V30 117 2 120 122
M  V30 118 1 122 123
M  V30 119 2 123 124
M  V30 120 1 123 125
M  V30 121 1 125 126
M  V30 122 1 126 127
M  V30 123 2 128 129
M  V30 124 1 129 130
M  V30 125 1 129 131
M  V30 126 1 130 132
M  V30 127 1 130 133
M  V30 128 2 131 134
M  V30 129 1 131 135
M  V30 130 1 132 136
M  V30 131 1 133 137
M  V30 132 1 134 138
M  V30 133 2 135 139
M  V30 134 2 136 140
M  V30 135 2 137 141
M  V30 136 2 138 142
M  V30 137 1 140 143
M  V30 138 1 142 144
M  V30 139 1 143 145
M  V30 140 1 144 146
M  V30 141 1 144 147
M  V30 142 1 145 148
M  V30 143 1 145 149
M  V30 144 2 148 150
M  V30 145 1 148 151
M  V30 146 1 149 152
M  V30 147 2 151 153
M  V30 148 1 151 154
M  V30 149 2 152 155
M  V30 150 1 153 156
M  V30 151 2 154 157
M  V30 152 2 156 158
M  V30 153 1 158 159
M  V30 154 1 159 160
M  V30 155 1 159 161
M  V30 156 2 162 163
M  V30 157 1 163 164
M  V30 158 1 163 165
M  V30 159 1 164 166
M  V30 160 1 164 167
M  V30 161 2 165 168
M  V30 162 1 165 169
M  V30 163 1 166 170
M  V30 164 1 167 171
M  V30 165 1 168 172
M  V30 166 2 169 173
M  V30 167 2 170 174
M  V30 168 2 171 175
M  V30 169 2 172 176
M  V30 170 1 174 177
M  V30 171 1 176 178
M  V30 172 1 177 179
M  V30 173 1 178 180
M  V30 174 1 178 181
M  V30 175 1 179 182
M  V30 176 1 179 183
M  V30 177 2 182 184
M  V30 178 1 182 185
M  V30 179 1 183 186
M  V30 180 2 185 187
M  V30 181 2 186 188
M  V30 182 2 189 190
M  V30 183 1 190 191
M  V30 184 1 190 192
M  V30 185 1 191 193
M  V30 186 1 191 194
M  V30 187 2 192 195
M  V30 188 1 192 196
M  V30 189 1 193 197
M  V30 190 1 194 198
M  V30 191 1 195 199
M  V30 192 2 196 200
M  V30 193 2 197 201
M  V30 194 2 198 202
M  V30 195 2 199 203
M  V30 196 1 203 204
M  V30 197 1 204 205
M  V30 198 1 204 206
M  V30 199 2 207 208
M  V30 200 1 208 209
M  V30 201 1 208 210
M  V30 202 1 209 211
M  V30 203 2 210 212
M  V30 204 1 210 213
M  V30 205 1 211 214
M  V30 206 1 212 215
M  V30 207 2 213 216
M  V30 208 1 214 217
M  V30 209 2 215 218
M  V30 210 1 217 219
M  V30 211 1 218 220
M  V30 212 2 219 221
M  V30 213 1 219 222
M  V30 214 1 220 223
M  V30 215 1 220 224
M  V30 216 2 222 225
M  V30 217 1 222 226
M  V30 218 2 227 228
M  V30 219 1 228 229
M  V30 220 1 228 230
M  V30 221 1 229 231
M  V30 222 2 230 232
M  V30 223 1 230 233
M  V30 224 1 231 234
M  V30 225 1 232 235
M  V30 226 2 233 236
M  V30 227 1 234 237
M  V30 228 2 235 238
M  V30 229 1 237 239
M  V30 230 1 238 240
M  V30 231 2 239 241
M  V30 232 1 239 242
M  V30 233 1 240 243
M  V30 234 1 240 244
M  V30 235 2 242 245
M  V30 236 1 242 246
M  V30 237 1 245 247
M  V30 238 2 246 248
M  V30 239 2 247 249
M  V30 240 1 249 250
M  V30 241 1 250 251
M  V30 242 1 250 252
M  V30 243 2 253 254
M  V30 244 1 254 255
M  V30 245 1 254 256
M  V30 246 1 255 257
M  V30 247 2 256 258
M  V30 248 1 256 259
M  V30 249 1 257 260
M  V30 250 1 258 261
M  V30 251 2 259 262
M  V30 252 1 260 263
M  V30 253 2 261 264
M  V30 254 1 263 265
M  V30 255 1 264 266
M  V30 256 1 265 267
M  V30 257 1 266 268
M  V30 258 1 266 269
M  V30 259 2 267 270
M  V30 260 1 10 12
M  V30 261 1 25 28
M  V30 262 1 49 50
M  V30 263 1 63 65
M  V30 264 1 75 76
M  V30 265 1 89 91
M  V30 266 1 109 110
M  V30 267 1 115 116
M  V30 268 1 121 122
M  V30 269 1 139 142
M  V30 270 1 157 158
M  V30 271 1 173 176
M  V30 272 1 200 203
M  V30 273 1 216 218
M  V30 274 1 236 238
M  V30 275 1 248 249
M  V30 276 1 262 264
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00073001.cdx

>  <name>
US20220000721A1-20220106-C00051

>  <Row No>
484

$$$$
US20220000721A1-20220106-C00052
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 37 36 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.343 0.7914 0.0 0
M  V30 3 O -1.379 2.3264 0.0 0
M  V30 4 C -2.6861 0.0839 0.0 0
M  V30 5 C -2.7221 -1.379 0.0 0
M  V30 6 C -4.0292 0.8754 0.0 0
M  V30 7 C -4.0652 -2.0865 0.0 0
M  V30 8 C -5.3723 0.1678 0.0 0
M  V30 9 C -5.4083 -1.2951 0.0 0
M  V30 10 N -6.7514 -2.0026 0.0 0
M  V30 11 C -8.0945 -1.2111 0.0 0
M  V30 12 C -6.7874 -3.4656 0.0 0
M  V30 13 O 5.6601 -12.0878 0.0 0
M  V30 14 C 5.6242 -13.5508 0.0 0
M  V30 15 N 6.8953 -14.2584 0.0 0
M  V30 16 C 4.2811 -14.2584 0.0 0
M  V30 17 C 8.1665 -13.4669 0.0 0
M  V30 18 C 6.8593 -15.7214 0.0 0
M  V30 19 C 4.2451 -15.7214 0.0 0
M  V30 20 C 2.938 -13.4669 0.0 0
M  V30 21 C 9.4376 -14.1744 0.0 0
M  V30 22 C 8.1305 -16.4289 0.0 0
M  V30 23 C 2.902 -16.4289 0.0 0
M  V30 24 C 1.5949 -14.1744 0.0 0
M  V30 25 C 10.7087 -13.3829 0.0 0
M  V30 26 C 8.0945 -17.8919 0.0 0
M  V30 27 C 1.5589 -15.6374 0.0 0
M  V30 28 N 0.2158 -16.3449 0.0 0
M  V30 29 C -1.1272 -15.5535 0.0 0
M  V30 30 C 0.1798 -17.808 0.0 0
M  V30 31 C -1.9187 -7.7707 0.0 0
M  V30 32 C -3.2618 -8.4782 0.0 0
M  V30 33 C -0.6475 -8.4782 0.0 0
M  V30 34 C 0.6235 -7.6868 0.0 0
M  V30 35 C 1.8947 -8.3943 0.0 0
M  V30 36 C 3.1658 -7.6028 0.0 0
M  V30 37 C 4.437 -8.3104 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 2 7 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 10 12
M  V30 12 2 13 14
M  V30 13 1 14 15
M  V30 14 1 14 16
M  V30 15 1 15 17
M  V30 16 1 15 18
M  V30 17 2 16 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 2 20 24
M  V30 23 2 21 25
M  V30 24 2 22 26
M  V30 25 2 23 27
M  V30 26 1 27 28
M  V30 27 1 28 29
M  V30 28 1 28 30
M  V30 29 2 31 32
M  V30 30 1 31 33
M  V30 31 1 33 34
M  V30 32 1 34 35
M  V30 33 1 35 36
M  V30 34 2 36 37
M  V30 35 1 8 9
M  V30 36 1 24 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00074001.cdx

>  <name>
US20220000721A1-20220106-C00052

>  <Row No>
485

$$$$
US20220000721A1-20220106-C00053
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 42 42 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3371 0.7709 0.0 0
M  V30 3 O -1.3733 2.3129 0.0 0
M  V30 4 C -2.6743 0.0481 0.0 0
M  V30 5 C -2.7104 -1.4215 0.0 0
M  V30 6 C -4.0115 0.8191 0.0 0
M  V30 7 C -4.0476 -2.1443 0.0 0
M  V30 8 C -5.3487 0.0963 0.0 0
M  V30 9 C -5.3848 -1.3612 0.0 0
M  V30 10 N -6.722 -2.084 0.0 0
M  V30 11 C -8.0592 -1.301 0.0 0
M  V30 12 C -6.7581 -3.5537 0.0 0
M  V30 13 O -1.0601 -11.4684 0.0 0
M  V30 14 C -1.0962 -12.938 0.0 0
M  V30 15 N 0.1686 -13.6608 0.0 0
M  V30 16 C -2.4334 -13.6608 0.0 0
M  V30 17 C 1.4335 -12.8778 0.0 0
M  V30 18 C -2.4695 -15.1305 0.0 0
M  V30 19 C -3.7706 -12.8778 0.0 0
M  V30 20 C 2.6984 -13.6006 0.0 0
M  V30 21 C -3.8067 -15.8533 0.0 0
M  V30 22 C -5.1077 -13.6006 0.0 0
M  V30 23 C 3.9633 -12.8296 0.0 0
M  V30 24 C -5.1439 -15.0703 0.0 0
M  V30 25 C 5.2282 -13.5524 0.0 0
M  V30 26 N -6.481 -15.7931 0.0 0
M  V30 27 O 5.1921 -15.0221 0.0 0
M  V30 28 C 6.4931 -12.7694 0.0 0
M  V30 29 C -7.8182 -15.0101 0.0 0
M  V30 30 C -6.5172 -17.2628 0.0 0
M  V30 31 C 6.457 -11.2274 0.0 0
M  V30 32 C 7.758 -13.4922 0.0 0
M  V30 33 C 7.7219 -10.4444 0.0 0
M  V30 34 C 9.0229 -12.7092 0.0 0
M  V30 35 C 8.9867 -11.1672 0.0 0
M  V30 36 N 10.2516 -10.3842 0.0 0
M  V30 37 C 11.5165 -11.107 0.0 0
M  V30 38 C 10.2155 -8.8422 0.0 0
M  V30 39 N 3.1803 -0.5782 0.0 0
M  V30 40 C 4.4452 0.1927 0.0 0
M  V30 41 C 5.7101 -0.542 0.0 0
M  V30 42 N 6.975 0.2288 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 2 7 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 10 12
M  V30 12 2 13 14
M  V30 13 1 14 15
M  V30 14 1 14 16
M  V30 15 1 15 17
M  V30 16 2 16 18
M  V30 17 1 16 19
M  V30 18 1 17 20
M  V30 19 1 18 21
M  V30 20 2 19 22
M  V30 21 1 20 23
M  V30 22 2 21 24
M  V30 23 1 23 25
M  V30 24 1 24 26
M  V30 25 2 25 27
M  V30 26 1 25 28
M  V30 27 1 26 29
M  V30 28 1 26 30
M  V30 29 2 28 31
M  V30 30 1 28 32
M  V30 31 1 31 33
M  V30 32 2 32 34
M  V30 33 2 33 35
M  V30 34 1 35 36
M  V30 35 1 36 37
M  V30 36 1 36 38
M  V30 37 1 39 40
M  V30 38 1 40 41
M  V30 39 1 41 42
M  V30 40 1 8 9
M  V30 41 1 22 24
M  V30 42 1 34 35
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00075001.cdx

>  <name>
US20220000721A1-20220106-C00053

>  <Row No>
486

$$$$
US20220000721A1-20220106-C00054
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 31 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.327 0.7771 0.0 0
M  V30 3 O -1.3629 2.3074 0.0 0
M  V30 4 C -2.6541 0.0478 0.0 0
M  V30 5 C -2.69 -1.4107 0.0 0
M  V30 6 C -3.9812 0.8249 0.0 0
M  V30 7 C -4.0171 -2.1281 0.0 0
M  V30 8 C -5.3083 0.0956 0.0 0
M  V30 9 C -5.3442 -1.3629 0.0 0
M  V30 10 N -6.6712 -2.0802 0.0 0
M  V30 11 C -7.9983 -1.3031 0.0 0
M  V30 12 C -6.7071 -3.5388 0.0 0
M  V30 13 O 5.8343 -7.9386 0.0 0
M  V30 14 C 5.7985 -9.3972 0.0 0
M  V30 15 N 7.0538 -10.1145 0.0 0
M  V30 16 C 4.4714 -10.1145 0.0 0
M  V30 17 C 8.3092 -9.3374 0.0 0
M  V30 18 C 4.4355 -11.5731 0.0 0
M  V30 19 C 3.1443 -9.3374 0.0 0
M  V30 20 C 9.5645 -10.0547 0.0 0
M  V30 21 C 3.1084 -12.3024 0.0 0
M  V30 22 C 1.8172 -10.0547 0.0 0
M  V30 23 C 10.8199 -9.2776 0.0 0
M  V30 24 C 1.7814 -11.5253 0.0 0
M  V30 25 N 0.4543 -12.2546 0.0 0
M  V30 26 C -0.8727 -11.4774 0.0 0
M  V30 27 C 0.4184 -13.7132 0.0 0
M  V30 28 N 6.0256 0.0 0.0 0
M  V30 29 C 4.6986 -0.7173 0.0 0
M  V30 30 C 3.3715 0.0478 0.0 0
M  V30 31 C 2.0444 -0.6695 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 2 7 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 10 12
M  V30 12 2 13 14
M  V30 13 1 14 15
M  V30 14 1 14 16
M  V30 15 1 15 17
M  V30 16 2 16 18
M  V30 17 1 16 19
M  V30 18 1 17 20
M  V30 19 1 18 21
M  V30 20 2 19 22
M  V30 21 2 20 23
M  V30 22 2 21 24
M  V30 23 1 24 25
M  V30 24 1 25 26
M  V30 25 1 25 27
M  V30 26 1 28 29
M  V30 27 1 29 30
M  V30 28 2 30 31
M  V30 29 1 8 9
M  V30 30 1 22 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00076001.cdx

>  <name>
US20220000721A1-20220106-C00054

>  <Row No>
487

$$$$
US20220000721A1-20220106-C00055
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 39 38 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0394 -1.4735 0.0 0
M  V30 3 N -1.3814 -2.1971 0.0 0
M  V30 4 C 1.2235 -2.1971 0.0 0
M  V30 5 C -2.7234 -1.3946 0.0 0
M  V30 6 C 2.4866 -1.3946 0.0 0
M  V30 7 O -4.0654 -2.1182 0.0 0
M  V30 8 O -4.2101 -11.8936 0.0 0
M  V30 9 C -2.9471 -11.0911 0.0 0
M  V30 10 N -1.684 -11.8147 0.0 0
M  V30 11 C -2.9865 -9.5386 0.0 0
M  V30 12 C -1.7235 -13.2883 0.0 0
M  V30 13 C -4.3285 -8.736 0.0 0
M  V30 14 C -0.4604 -14.0119 0.0 0
M  V30 15 C -0.4999 -15.4854 0.0 0
M  V30 16 C 0.8025 -13.2093 0.0 0
M  V30 17 N -1.8419 -16.2091 0.0 0
M  V30 18 C 0.763 -16.2091 0.0 0
M  V30 19 C 2.0656 -13.9329 0.0 0
M  V30 20 C -3.1839 -15.4065 0.0 0
M  V30 21 C -1.8814 -17.6826 0.0 0
M  V30 22 C 2.0261 -15.4065 0.0 0
M  V30 23 C 3.3286 -13.1304 0.0 0
M  V30 24 C 4.5917 -13.854 0.0 0
M  V30 25 C 3.2891 -11.5779 0.0 0
M  V30 26 C 4.5917 -12.3278 0.0 0
M  V30 27 N -13.4725 -2.6313 0.0 0
M  V30 28 C -12.2094 -1.8287 0.0 0
M  V30 29 C -14.8144 -1.8287 0.0 0
M  V30 30 C -13.5119 -4.1049 0.0 0
M  V30 31 C -10.9464 -2.5524 0.0 0
M  V30 32 C -12.2489 -0.2762 0.0 0
M  V30 33 C -9.6833 -1.7498 0.0 0
M  V30 34 C -10.9858 0.5262 0.0 0
M  V30 35 C -9.7228 -0.1973 0.0 0
M  V30 36 C -8.4597 0.6052 0.0 0
M  V30 37 C -7.1967 -0.1184 0.0 0
M  V30 38 C -8.4992 2.1577 0.0 0
M  V30 39 C -7.1967 1.4077 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 8 9
M  V30 8 1 9 10
M  V30 9 1 9 11
M  V30 10 1 10 12
M  V30 11 2 11 13
M  V30 12 1 12 14
M  V30 13 2 14 15
M  V30 14 1 14 16
M  V30 15 1 15 17
M  V30 16 1 15 18
M  V30 17 2 16 19
M  V30 18 1 17 20
M  V30 19 1 17 21
M  V30 20 2 18 22
M  V30 21 1 19 23
M  V30 22 1 23 24
M  V30 23 1 23 25
M  V30 24 1 23 26
M  V30 25 1 27 28
M  V30 26 1 27 29
M  V30 27 1 27 30
M  V30 28 2 28 31
M  V30 29 1 28 32
M  V30 30 1 31 33
M  V30 31 2 32 34
M  V30 32 2 33 35
M  V30 33 1 35 36
M  V30 34 1 36 37
M  V30 35 1 36 38
M  V30 36 1 36 39
M  V30 37 1 19 22
M  V30 38 1 34 35
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00077001.cdx

>  <name>
US20220000721A1-20220106-C00055

>  <Row No>
488

$$$$
US20220000721A1-20220106-C00056
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 19 19 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3176 -0.7241 0.0 0
M  V30 3 N -2.6353 0.0474 0.0 0
M  V30 4 C -1.3532 -2.1723 0.0 0
M  V30 5 C -3.9529 -0.6766 0.0 0
M  V30 6 C -2.6709 -2.8846 0.0 0
M  V30 7 C -5.2706 0.0949 0.0 0
M  V30 8 C -6.5882 -0.6172 0.0 0
M  V30 9 C -5.3062 1.6144 0.0 0
M  V30 10 N -6.6239 -2.0655 0.0 0
M  V30 11 C -7.9059 0.1543 0.0 0
M  V30 12 C -6.6239 2.3741 0.0 0
M  V30 13 C -5.3774 -2.7777 0.0 0
M  V30 14 C -7.9415 -2.7777 0.0 0
M  V30 15 C -7.9415 1.6737 0.0 0
M  V30 16 C -6.6595 3.8936 0.0 0
M  V30 17 C -7.9771 4.6652 0.0 0
M  V30 18 C -5.413 4.6652 0.0 0
M  V30 19 C -6.6951 5.413 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 7 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 8 11
M  V30 11 2 9 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 2 11 15
M  V30 15 1 12 16
M  V30 16 1 16 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 1 12 15
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00081001.cdx

>  <name>
US20220000721A1-20220106-C00056

>  <Row No>
489

$$$$
US20220000723A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000723A1-20220106-C00001

>  <Row No>
490

$$$$
US20220000723A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000723A1-20220106-C00002

>  <Row No>
491

$$$$
US20220000723A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000723A1-20220106-C00003

>  <Row No>
492

$$$$
US20220000723A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 127 125 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.1204 -1.3245 0.0 0
M  V30 3 C 1.0435 -1.8864 0.0 0
M  V30 4 C -1.5252 -1.8864 0.0 0
M  V30 5 C 0.9231 -3.211 0.0 0
M  V30 6 C 2.2075 -2.4483 0.0 0
M  V30 7 C 2.2075 -1.0435 0.0 0
M  V30 8 C -1.6456 -3.211 0.0 0
M  V30 9 C -2.93 -2.4483 0.0 0
M  V30 10 C -2.93 -1.0435 0.0 0
M  V30 11 C -0.4816 -3.7729 0.0 0
M  V30 12 C 3.3715 -1.6055 0.0 0
M  V30 13 C 2.0871 0.5619 0.0 0
M  V30 14 C -4.3348 -1.6055 0.0 0
M  V30 15 C -3.0504 0.5619 0.0 0
M  V30 16 C 4.5355 -2.1674 0.0 0
M  V30 17 C 3.2511 1.4048 0.0 0
M  V30 18 C -5.7396 -2.1674 0.0 0
M  V30 19 C -4.4552 1.4048 0.0 0
M  V30 20 N 5.6995 -1.3245 0.0 0
M  V30 21 N 3.1307 3.0103 0.0 0
M  V30 22 N -7.1444 -1.3245 0.0 0
M  V30 23 N -4.5756 3.0103 0.0 0
M  V30 24 O -0.6422 -26.3302 0.0 0
M  V30 25 C -0.7626 -27.6547 0.0 0
M  V30 26 C 0.4013 -28.2167 0.0 0
M  V30 27 C -2.1674 -28.2167 0.0 0
M  V30 28 C 0.2809 -29.5412 0.0 0
M  V30 29 C 1.5653 -28.7786 0.0 0
M  V30 30 C 1.5653 -27.3738 0.0 0
M  V30 31 C -2.2878 -29.5412 0.0 0
M  V30 32 C -3.5722 -28.7786 0.0 0
M  V30 33 C -3.5722 -27.3738 0.0 0
M  V30 34 C 2.7293 -27.9357 0.0 0
M  V30 35 C 1.4449 -25.7683 0.0 0
M  V30 36 C -4.977 -27.9357 0.0 0
M  V30 37 C -3.6926 -25.7683 0.0 0
M  V30 38 C 3.8933 -28.4976 0.0 0
M  V30 39 C 2.6089 -24.9254 0.0 0
M  V30 40 C -6.3818 -28.4976 0.0 0
M  V30 41 C -5.0974 -24.9254 0.0 0
M  V30 42 N 5.0573 -27.6547 0.0 0
M  V30 43 N 2.4885 -23.3199 0.0 0
M  V30 44 N -7.7866 -27.6547 0.0 0
M  V30 45 N -5.2178 -23.3199 0.0 0
M  V30 46 O -0.6422 -8.6697 0.0 0
M  V30 47 C -0.7626 -9.9942 0.0 0
M  V30 48 C 0.4013 -10.5561 0.0 0
M  V30 49 C -2.1674 -10.5561 0.0 0
M  V30 50 C 0.2809 -11.8807 0.0 0
M  V30 51 C 1.5653 -11.1181 0.0 0
M  V30 52 C 1.5653 -9.7132 0.0 0
M  V30 53 C -2.2878 -11.8807 0.0 0
M  V30 54 C -3.5722 -11.1181 0.0 0
M  V30 55 C -3.5722 -9.7132 0.0 0
M  V30 56 C -1.1238 -12.4426 0.0 0
M  V30 57 C 2.7293 -10.2752 0.0 0
M  V30 58 C 1.4449 -8.1077 0.0 0
M  V30 59 C -4.977 -10.2752 0.0 0
M  V30 60 C -3.6926 -8.1077 0.0 0
M  V30 61 C 3.8933 -10.8371 0.0 0
M  V30 62 C 2.6089 -7.2648 0.0 0
M  V30 63 C -6.3818 -10.8371 0.0 0
M  V30 64 C -5.0974 -7.2648 0.0 0
M  V30 65 N 5.0573 -9.9942 0.0 0
M  V30 66 N 2.4885 -5.6593 0.0 0
M  V30 67 N -7.7866 -9.9942 0.0 0
M  V30 68 N -5.2178 -5.6593 0.0 0
M  V30 69 O -0.6422 -40.4586 0.0 0
M  V30 70 C -0.7626 -41.7831 0.0 0
M  V30 71 C 0.4013 -42.3451 0.0 0
M  V30 72 C -2.1674 -42.3451 0.0 0
M  V30 73 C 0.2809 -43.6696 0.0 0
M  V30 74 C 1.5653 -42.907 0.0 0
M  V30 75 C 1.5653 -41.5022 0.0 0
M  V30 76 C -2.2878 -43.6696 0.0 0
M  V30 77 C -3.5722 -42.907 0.0 0
M  V30 78 C -3.5722 -41.5022 0.0 0
M  V30 79 C 2.7293 -42.0641 0.0 0
M  V30 80 C 1.4449 -39.8967 0.0 0
M  V30 81 C -4.977 -42.0641 0.0 0
M  V30 82 C -3.6926 -39.8967 0.0 0
M  V30 83 C 3.8933 -42.626 0.0 0
M  V30 84 C 2.6089 -39.0538 0.0 0
M  V30 85 C -6.3818 -42.626 0.0 0
M  V30 86 C -5.0974 -39.0538 0.0 0
M  V30 87 N 5.0573 -41.7831 0.0 0
M  V30 88 N 2.4885 -37.4483 0.0 0
M  V30 89 N -7.7866 -41.7831 0.0 0
M  V30 90 N -5.2178 -37.4483 0.0 0
M  V30 91 N 0.6422 7.3853 0.0 0
M  V30 92 C 1.2041 8.7901 0.0 0
M  V30 93 C 1.2041 6.2213 0.0 0
M  V30 94 ? -0.8428 7.4254 0.0 0
M  V30 95 C 2.5286 8.9105 0.0 0
M  V30 96 C 2.5286 6.3417 0.0 0
M  V30 97 N -2.4483 7.5458 0.0 0
M  V30 98 C 3.0905 10.3153 0.0 0
M  V30 99 C 3.0905 5.1777 0.0 0
M  V30 100 C -3.2912 8.9506 0.0 0
M  V30 101 C -3.2912 6.3818 0.0 0
M  V30 102 N 4.4151 10.4357 0.0 0
M  V30 103 N 4.4151 5.2981 0.0 0
M  V30 104 C -4.8967 9.071 0.0 0
M  V30 105 C -4.8967 6.5022 0.0 0
M  V30 106 C -5.7396 10.4759 0.0 0
M  V30 107 C -5.7396 5.3382 0.0 0
M  V30 108 N -7.3451 10.5963 0.0 0
M  V30 109 N -7.3451 5.4587 0.0 0
M  V30 110 N 3.5321 -16.3761 0.0 0
M  V30 111 C 1.9266 -16.2557 0.0 0
M  V30 112 C 1.0837 -17.4196 0.0 0 CFG=2
M  V30 113 C -0.5217 -17.2992 0.0 0
M  V30 114 C 1.6456 -18.5836 0.0 0
M  V30 115 C -1.3646 -18.4632 0.0 0
M  V30 116 C 2.9701 -18.4632 0.0 0
M  V30 117 C -2.9701 -18.3428 0.0 0
M  V30 118 C 3.5321 -19.6272 0.0 0
M  V30 119 C -3.813 -16.938 0.0 0
M  V30 120 C -3.813 -19.5068 0.0 0
M  V30 121 N 4.8566 -19.5068 0.0 0
M  V30 122 C -5.4185 -16.8176 0.0 0
M  V30 123 C -5.4185 -19.3864 0.0 0
M  V30 124 C -6.2614 -15.4128 0.0 0
M  V30 125 C -6.2614 -20.5504 0.0 0
M  V30 126 N -7.8669 -15.2924 0.0 0
M  V30 127 N -7.8669 -20.43 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 4 9
M  V30 9 1 4 10
M  V30 10 1 5 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 1 9 14
M  V30 14 1 10 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 1 15 19
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 2 24 25
M  V30 24 1 25 26
M  V30 25 1 25 27
M  V30 26 1 26 28
M  V30 27 1 26 29
M  V30 28 1 26 30
M  V30 29 1 27 31
M  V30 30 1 27 32
M  V30 31 1 27 33
M  V30 32 1 29 34
M  V30 33 1 30 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 40 44
M  V30 43 1 41 45
M  V30 44 1 46 47
M  V30 45 1 47 48
M  V30 46 1 47 49
M  V30 47 1 48 50
M  V30 48 1 48 51
M  V30 49 1 48 52
M  V30 50 1 49 53
M  V30 51 1 49 54
M  V30 52 1 49 55
M  V30 53 1 50 56
M  V30 54 1 51 57
M  V30 55 1 52 58
M  V30 56 1 54 59
M  V30 57 1 55 60
M  V30 58 1 57 61
M  V30 59 1 58 62
M  V30 60 1 59 63
M  V30 61 1 60 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 69 70
M  V30 67 1 70 71
M  V30 68 1 70 72
M  V30 69 1 71 73
M  V30 70 1 71 74
M  V30 71 1 71 75
M  V30 72 1 72 76
M  V30 73 1 72 77
M  V30 74 1 72 78
M  V30 75 1 74 79
M  V30 76 1 75 80
M  V30 77 1 77 81
M  V30 78 1 78 82
M  V30 79 1 79 83
M  V30 80 1 80 84
M  V30 81 1 81 85
M  V30 82 1 82 86
M  V30 83 1 83 87
M  V30 84 1 84 88
M  V30 85 1 85 89
M  V30 86 1 86 90
M  V30 87 1 91 92
M  V30 88 1 91 93
M  V30 89 1 91 94
M  V30 90 1 92 95
M  V30 91 1 93 96
M  V30 92 1 94 97
M  V30 93 1 95 98
M  V30 94 1 96 99
M  V30 95 1 97 100
M  V30 96 1 97 101
M  V30 97 1 98 102
M  V30 98 1 99 103
M  V30 99 1 100 104
M  V30 100 1 101 105
M  V30 101 1 104 106
M  V30 102 1 105 107
M  V30 103 1 106 108
M  V30 104 1 107 109
M  V30 105 1 110 111
M  V30 106 1 112 111 CFG=1
M  V30 107 1 112 113
M  V30 108 1 112 114
M  V30 109 1 113 115
M  V30 110 1 114 116
M  V30 111 1 115 117
M  V30 112 1 116 118
M  V30 113 1 117 119
M  V30 114 1 117 120
M  V30 115 1 118 121
M  V30 116 1 119 122
M  V30 117 1 120 123
M  V30 118 1 122 124
M  V30 119 1 123 125
M  V30 120 1 124 126
M  V30 121 1 125 127
M  V30 122 1 8 11
M  V30 123 1 28 31
M  V30 124 1 53 56
M  V30 125 1 73 76
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 112)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000723A1-20220106-C00004

>  <Row No>
493

$$$$
US20220000723A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000723A1-20220106-C00005

>  <Row No>
494

$$$$
US20220000723A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000723A1-20220106-C00006

>  <Row No>
495

$$$$
US20220000723A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.3668 -1.4428 0.0 0
M  V30 3 O 1.7851 -1.8829 0.0 0
M  V30 4 O -0.5624 -2.641 0.0 0
M  V30 5 C 1.7484 -3.3746 0.0 0
M  V30 6 C 0.2934 -3.8393 0.0 0
M  V30 7 C 3.0323 -4.1083 0.0 0
M  V30 8 O 4.3161 -3.3257 0.0 0
M  V30 9 C 5.6 -4.0594 0.0 0
M  V30 10 C 6.8838 -3.2646 0.0 0
M  V30 11 C 8.1677 -3.9982 0.0 0
M  V30 12 C 6.8472 -1.6995 0.0 0
M  V30 13 C 9.4515 -3.2157 0.0 0
M  V30 14 C 8.131 -0.917 0.0 0
M  V30 15 C 9.4149 -1.6506 0.0 0
M  V30 16 C 10.6987 -0.8559 0.0 0
M  V30 17 O 11.9826 -1.5895 0.0 0
M  V30 18 C 13.2664 -0.8069 0.0 0
M  V30 19 C 14.5503 -1.5406 0.0 0
M  V30 20 O 14.5136 -3.0323 0.0 0
M  V30 21 C 15.9686 -1.027 0.0 0
M  V30 22 C 15.9319 -3.4725 0.0 0
M  V30 23 O 16.8245 -2.2253 0.0 0
M  V30 24 O 16.2987 -4.9153 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 2 22 24
M  V30 24 1 5 6
M  V30 25 1 14 15
M  V30 26 1 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000723A1-20220106-C00007

>  <Row No>
496

$$$$
US20220000723A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.7317 -1.2806 0.0 0
M  V30 3 O 2.2197 -1.244 0.0 0
M  V30 4 O 0.2195 -2.6954 0.0 0
M  V30 5 C 2.6588 -2.6588 0.0 0
M  V30 6 C 1.4147 -3.5491 0.0 0
M  V30 7 C 3.9394 -3.3906 0.0 0
M  V30 8 O 5.2201 -2.61 0.0 0
M  V30 9 C 6.5007 -3.3418 0.0 0
M  V30 10 C 7.7813 -2.549 0.0 0
M  V30 11 C 9.062 -3.2808 0.0 0
M  V30 12 C 7.7447 -0.9879 0.0 0
M  V30 13 C 7.7447 -4.037 0.0 0
M  V30 14 O 10.3426 -2.488 0.0 0
M  V30 15 C 11.6232 -3.2198 0.0 0
M  V30 16 C 12.9038 -2.4271 0.0 0
M  V30 17 O 13.3429 -0.9391 0.0 0
M  V30 18 C 14.0991 -3.2808 0.0 0
M  V30 19 C 14.8309 -0.9025 0.0 0
M  V30 20 O 15.2944 -2.3539 0.0 0
M  V30 21 O 15.5627 0.4512 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 2 19 21
M  V30 21 1 5 6
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000723A1-20220106-C00008

>  <Row No>
497

$$$$
US20220000723A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3249 -0.7162 0.0 0
M  V30 3 C -0.0358 -1.4562 0.0 0
M  V30 4 C -2.6499 -1.4443 0.0 0
M  V30 5 O -3.9749 -0.6803 0.0 0
M  V30 6 C -5.2999 -1.4085 0.0 0
M  V30 7 C -6.6249 -0.6445 0.0 0
M  V30 8 C -5.3357 -2.8648 0.0 0
M  V30 9 O -7.9499 -1.3727 0.0 0
M  V30 10 C -9.2748 -0.6087 0.0 0
M  V30 11 C -10.5998 -1.3369 0.0 0
M  V30 12 O -11.9248 -2.065 0.0 0
M  V30 13 C -11.9248 -0.5729 0.0 0
M  V30 14 O 1.8143 -6.8755 0.0 0
M  V30 15 C 0.4894 -7.6037 0.0 0
M  V30 16 C 3.0677 -7.6037 0.0 0
M  V30 17 C -0.8355 -6.8397 0.0 0
M  V30 18 C 0.4535 -9.06 0.0 0
M  V30 19 C 4.3211 -6.8397 0.0 0
M  V30 20 O -2.1605 -7.5679 0.0 0
M  V30 21 O 4.2853 -5.3118 0.0 0
M  V30 22 C 5.5744 -7.5679 0.0 0
M  V30 23 C -3.4855 -6.792 0.0 0
M  V30 24 N 6.8278 -6.792 0.0 0
M  V30 25 C -4.8105 -7.5201 0.0 0
M  V30 26 O -4.8463 -8.9764 0.0 0
M  V30 27 C -6.1355 -6.7562 0.0 0
M  V30 28 N -7.4604 -7.4843 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 4 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 13 1 14 15
M  V30 14 1 14 16
M  V30 15 1 15 17
M  V30 16 1 15 18
M  V30 17 1 16 19
M  V30 18 1 17 20
M  V30 19 1 19 21
M  V30 20 1 19 22
M  V30 21 1 20 23
M  V30 22 1 22 24
M  V30 23 1 23 25
M  V30 24 1 25 26
M  V30 25 1 25 27
M  V30 26 1 27 28
M  V30 27 1 2 3
M  V30 28 1 12 13
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000723A1-20220106-C00009

>  <Row No>
498

$$$$
US20220000723A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.3668 -1.4428 0.0 0
M  V30 3 O 1.7851 -1.8829 0.0 0
M  V30 4 O -0.5624 -2.641 0.0 0
M  V30 5 C 1.7484 -3.3746 0.0 0
M  V30 6 C 0.2934 -3.8393 0.0 0
M  V30 7 C 3.0323 -4.1083 0.0 0
M  V30 8 O 4.3161 -3.3257 0.0 0
M  V30 9 C 5.6 -4.0594 0.0 0
M  V30 10 C 6.8838 -3.2646 0.0 0
M  V30 11 C 8.1677 -3.9982 0.0 0
M  V30 12 C 6.8472 -1.6995 0.0 0
M  V30 13 C 9.4515 -3.2157 0.0 0
M  V30 14 C 8.131 -0.917 0.0 0
M  V30 15 C 9.4149 -1.6506 0.0 0
M  V30 16 C 10.6987 -0.8559 0.0 0
M  V30 17 O 11.9826 -1.5895 0.0 0
M  V30 18 C 13.2664 -0.8069 0.0 0
M  V30 19 C 14.5503 -1.5406 0.0 0
M  V30 20 O 14.5136 -3.0323 0.0 0
M  V30 21 C 15.9686 -1.027 0.0 0
M  V30 22 C 15.9319 -3.4725 0.0 0
M  V30 23 O 16.8245 -2.2253 0.0 0
M  V30 24 O 16.2987 -4.9153 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 2 22 24
M  V30 24 1 5 6
M  V30 25 1 14 15
M  V30 26 1 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000723A1-20220106-C00010

>  <Row No>
499

$$$$
US20220000723A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000723A1-20220106-C00011

>  <Row No>
500

$$$$
US20220000723A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000723A1-20220106-C00012

>  <Row No>
501

$$$$
US20220000726A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000726A1-20220106-C00001

>  <Row No>
502

$$$$
US20220000726A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000726A1-20220106-C00002

>  <Row No>
503

$$$$
US20220000726A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C -1.3409 0.7852 0.0 0
M  V30 3 C -0.0362 -1.4738 0.0 0
M  V30 4 C 1.2684 0.7852 0.0 0
M  V30 5 C -1.3771 2.3315 0.0 0
M  V30 6 C -1.3771 -2.1986 0.0 0
M  V30 7 C 1.2322 2.3315 0.0 0
M  V30 8 N -2.7181 3.1168 0.0 0
M  V30 9 N -1.4134 -3.6725 0.0 0
M  V30 10 C 2.5006 3.1168 0.0 0
M  V30 11 C -2.7543 4.6631 0.0 0
M  V30 12 C -4.0591 2.3919 0.0 0
M  V30 13 C 3.7691 2.3919 0.0 0
M  V30 14 C -4.0953 5.4483 0.0 0
M  V30 15 C -5.4 3.1651 0.0 0
M  V30 16 C 5.0376 3.1651 0.0 0
M  V30 17 N 6.3061 2.4402 0.0 0
M  V30 18 C 6.2698 0.9664 0.0 0
M  V30 19 C 7.5745 3.2255 0.0 0
M  V30 20 C 7.5383 0.2416 0.0 0
M  V30 21 C 8.843 2.5006 0.0 0
M  V30 22 N 7.502 -1.2322 0.0 0
M  V30 23 C 10.1115 3.2738 0.0 0
M  V30 24 C 11.3799 2.549 0.0 0
M  V30 25 C 12.6484 3.3342 0.0 0
M  V30 26 N 13.9169 2.6094 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000726A1-20220106-C00003

>  <Row No>
504

$$$$
US20220000726A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 795 794 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -2.1134 0.5943 0.0 0
M  V30 3 C -0.9081 0.9081 0.0 0
M  V30 4 C -0.9576 0.9576 0.0 0
M  V30 5 C -2.1629 0.6439 0.0 0
M  V30 6 O -0.1485 0.1485 0.0 0
M  V30 7 O -0.1485 0.1485 0.0 0
M  V30 8 C -2.262 0.7429 0.0 0
M  V30 9 C -1.0567 1.0567 0.0 0
M  V30 10 C -1.1062 1.1062 0.0 0
M  V30 11 C -2.3115 0.7925 0.0 0
M  V30 12 O -0.2971 0.2971 0.0 0
M  V30 13 O -0.2971 0.2971 0.0 0
M  V30 14 C -2.4106 0.8915 0.0 0
M  V30 15 C -1.2053 1.2053 0.0 0
M  V30 16 C -1.2548 1.2548 0.0 0
M  V30 17 C -2.4601 0.9411 0.0 0
M  V30 18 O -0.4457 0.4457 0.0 0
M  V30 19 O -0.4457 0.4457 0.0 0
M  V30 20 C -2.5592 1.0401 0.0 0
M  V30 21 C -1.3539 1.3539 0.0 0
M  V30 22 C -1.4034 1.4034 0.0 0
M  V30 23 C -2.6087 1.0897 0.0 0
M  V30 24 O -0.5943 0.5943 0.0 0
M  V30 25 O -0.5943 0.5943 0.0 0
M  V30 26 C -2.7078 1.1887 0.0 0
M  V30 27 C -1.5025 1.5025 0.0 0
M  V30 28 C -1.552 1.552 0.0 0
M  V30 29 C -2.7573 1.2383 0.0 0
M  V30 30 O -0.7429 0.7429 0.0 0
M  V30 31 O -0.7429 0.7429 0.0 0
M  V30 32 C -2.8564 1.3373 0.0 0
M  V30 33 C -1.6511 1.6511 0.0 0
M  V30 34 C -1.7006 1.7006 0.0 0
M  V30 35 C -2.9059 1.3869 0.0 0
M  V30 36 O -0.8915 0.8915 0.0 0
M  V30 37 O -0.8915 0.8915 0.0 0
M  V30 38 C -3.005 1.4859 0.0 0
M  V30 39 C -1.7996 1.7996 0.0 0
M  V30 40 C -1.8492 1.8492 0.0 0
M  V30 41 C -3.0545 1.5355 0.0 0
M  V30 42 O -1.0401 1.0401 0.0 0
M  V30 43 O -1.0401 1.0401 0.0 0
M  V30 44 C -3.1536 1.6345 0.0 0
M  V30 45 C -1.9482 1.9482 0.0 0
M  V30 46 C -1.9978 1.9978 0.0 0
M  V30 47 C -3.2031 1.6841 0.0 0
M  V30 48 O -1.1887 1.1887 0.0 0
M  V30 49 O -1.1887 1.1887 0.0 0
M  V30 50 C -3.3022 1.7831 0.0 0
M  V30 51 C -2.0968 2.0968 0.0 0
M  V30 52 C -2.1464 2.1464 0.0 0
M  V30 53 C -3.3517 1.8327 0.0 0
M  V30 54 O -1.3373 1.3373 0.0 0
M  V30 55 O -1.3373 1.3373 0.0 0
M  V30 56 C -3.4508 1.9317 0.0 0
M  V30 57 C -2.2454 2.2454 0.0 0
M  V30 58 C -2.295 2.295 0.0 0
M  V30 59 C -3.5003 1.9813 0.0 0
M  V30 60 O -1.4859 1.4859 0.0 0
M  V30 61 N -4.4084 2.8894 0.0 0
M  V30 62 C -0.3302 1.8492 0.0 0
M  V30 63 C -4.4579 4.1772 0.0 0
M  V30 64 C -5.5476 3.5498 0.0 0
M  V30 65 C -3.4673 4.8377 0.0 0
M  V30 66 C -6.6869 2.9884 0.0 0
M  V30 67 O -3.5168 6.1255 0.0 0
M  V30 68 N -7.8262 3.6489 0.0 0
M  V30 69 C -4.6395 4.3258 0.0 0
M  V30 70 C -8.4866 4.7881 0.0 0
M  V30 71 C -9.081 3.3847 0.0 0
M  V30 72 C -3.6489 4.9863 0.0 0
M  V30 73 C -7.9252 5.9274 0.0 0
M  V30 74 C -9.9891 4.2928 0.0 0
M  V30 75 O -3.6984 6.2741 0.0 0
M  V30 76 O -8.5857 7.0502 0.0 0
M  V30 77 N -11.2439 4.0286 0.0 0
M  V30 78 C -4.8212 4.4744 0.0 0
M  V30 79 C -8.0243 8.1894 0.0 0
M  V30 80 C -10.6826 5.1679 0.0 0
M  V30 81 C -12.3832 3.4673 0.0 0
M  V30 82 C -3.8305 5.1349 0.0 0
M  V30 83 C -11.343 6.2906 0.0 0
M  V30 84 C -12.4327 2.2785 0.0 0
M  V30 85 O -3.88 6.4227 0.0 0
M  V30 86 N -10.7816 7.4299 0.0 0
M  V30 87 N -13.572 1.7171 0.0 0
M  V30 88 C -5.0028 4.623 0.0 0
M  V30 89 C -11.6897 8.338 0.0 0
M  V30 90 C -11.1449 8.6847 0.0 0
M  V30 91 C -13.0106 0.7099 0.0 0
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M  V30 710 O -16.6761 11.8053 0.0 0
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M  V30 712 O -12.6639 1.7666 0.0 0
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M  V30 718 O -26.7313 9.2956 0.0 0
M  V30 719 O -25.2948 12.2511 0.0 0
M  V30 720 C -17.9309 11.5411 0.0 0
M  V30 721 C -12.9611 15.7515 0.0 0
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M  V30 731 C -13.9683 2.1794 0.0 0
M  V30 732 C -18.1786 -1.519 0.0 0
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M  V30 735 C -23.2474 2.9719 0.0 0
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M  V30 737 C -25.625 9.081 0.0 0
M  V30 738 C -25.0802 11.1449 0.0 0
M  V30 739 O -11.2109 16.9402 0.0 0
M  V30 740 O -12.8125 1.9152 0.0 0
M  V30 741 O -19.3178 -2.0803 0.0 0
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M  V30 747 O -25.4434 12.3997 0.0 0
M  V30 748 C -10.0221 16.9898 0.0 0
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M  V30 751 C -14.0838 -5.0028 0.0 0
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M  V30 753 C -22.1412 2.7573 0.0 0
M  V30 754 C -26.5166 0.3302 0.0 0
M  V30 755 C -24.8655 10.0386 0.0 0
M  V30 756 C -23.9739 10.9302 0.0 0
M  V30 757 C -18.3602 -1.3704 0.0 0
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M  V30 759 C -12.8785 -7.9583 0.0 0
M  V30 760 C -23.396 3.1205 0.0 0
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M  V30 762 C -25.7736 9.2296 0.0 0
M  V30 763 C -25.2288 11.2935 0.0 0
M  V30 764 O -19.4994 -1.9317 0.0 0
M  V30 765 O -12.119 -4.3589 0.0 0
M  V30 766 O -12.3172 -8.9489 0.0 0
M  V30 767 O -23.7593 4.3754 0.0 0
M  V30 768 O -28.7951 0.4292 0.0 0
M  V30 769 O -27.0285 9.5928 0.0 0
M  V30 770 O -25.592 12.5483 0.0 0
M  V30 771 C -20.6387 -1.2713 0.0 0
M  V30 772 C -14.2324 -4.8542 0.0 0
M  V30 773 C -14.2159 -7.8097 0.0 0
M  V30 774 C -25.0141 4.7386 0.0 0
M  V30 775 C -26.7148 0.4788 0.0 0
M  V30 776 C -25.0141 10.1872 0.0 0
M  V30 777 C -24.1225 11.0788 0.0 0
M  V30 778 C -13.4234 -3.9461 0.0 0
M  V30 779 C -13.0271 -7.7601 0.0 0
M  V30 780 C -27.854 -0.0825 0.0 0
M  V30 781 C -25.9222 9.3782 0.0 0
M  V30 782 C -25.3774 11.4421 0.0 0
M  V30 783 O -12.2676 -4.2103 0.0 0
M  V30 784 O -12.4658 -8.7508 0.0 0
M  V30 785 O -28.9933 0.5778 0.0 0
M  V30 786 O -27.1771 9.7414 0.0 0
M  V30 787 O -25.7406 12.6969 0.0 0
M  V30 788 C -11.4586 -3.3022 0.0 0
M  V30 789 C -14.3645 -7.6115 0.0 0
M  V30 790 C -30.1325 0.0165 0.0 0
M  V30 791 C -28.0852 8.9324 0.0 0
M  V30 792 C -26.9954 13.0602 0.0 0
M  V30 793 C -13.1757 -7.562 0.0 0
M  V30 794 O -12.6144 -8.5527 0.0 0
M  V30 795 C -11.4256 -8.5031 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 25 27
M  V30 27 1 26 28
M  V30 28 1 27 29
M  V30 29 1 28 30
M  V30 30 1 29 31
M  V30 31 1 30 32
M  V30 32 1 31 33
M  V30 33 1 32 34
M  V30 34 1 33 35
M  V30 35 1 34 36
M  V30 36 1 35 37
M  V30 37 1 36 38
M  V30 38 1 37 39
M  V30 39 1 38 40
M  V30 40 1 39 41
M  V30 41 1 40 42
M  V30 42 1 41 43
M  V30 43 1 42 44
M  V30 44 1 43 45
M  V30 45 1 44 46
M  V30 46 1 45 47
M  V30 47 1 46 48
M  V30 48 1 47 49
M  V30 49 1 48 50
M  V30 50 1 49 51
M  V30 51 1 50 52
M  V30 52 1 51 53
M  V30 53 1 52 54
M  V30 54 1 53 55
M  V30 55 1 54 56
M  V30 56 1 55 57
M  V30 57 1 56 58
M  V30 58 1 57 59
M  V30 59 1 58 60
M  V30 60 1 59 61
M  V30 61 1 60 62
M  V30 62 1 61 63
M  V30 63 1 61 64
M  V30 64 1 63 65
M  V30 65 1 64 66
M  V30 66 1 65 67
M  V30 67 1 66 68
M  V30 68 1 67 69
M  V30 69 1 68 70
M  V30 70 1 68 71
M  V30 71 1 69 72
M  V30 72 1 70 73
M  V30 73 1 71 74
M  V30 74 1 72 75
M  V30 75 1 73 76
M  V30 76 1 74 77
M  V30 77 1 75 78
M  V30 78 1 76 79
M  V30 79 1 77 80
M  V30 80 1 77 81
M  V30 81 1 78 82
M  V30 82 1 80 83
M  V30 83 1 81 84
M  V30 84 1 82 85
M  V30 85 1 83 86
M  V30 86 1 84 87
M  V30 87 1 85 88
M  V30 88 1 86 89
M  V30 89 1 86 90
M  V30 90 1 87 91
M  V30 91 1 87 92
M  V30 92 1 88 93
M  V30 93 1 89 94
M  V30 94 1 90 95
M  V30 95 1 91 96
M  V30 96 1 92 97
M  V30 97 1 93 98
M  V30 98 1 94 99
M  V30 99 1 95 100
M  V30 100 1 96 101
M  V30 101 1 97 102
M  V30 102 1 98 103
M  V30 103 1 99 104
M  V30 104 1 100 105
M  V30 105 1 100 106
M  V30 106 1 101 107
M  V30 107 1 101 108
M  V30 108 1 102 109
M  V30 109 1 102 110
M  V30 110 1 103 111
M  V30 111 1 104 112
M  V30 112 1 105 113
M  V30 113 1 106 114
M  V30 114 1 107 115
M  V30 115 1 108 116
M  V30 116 1 109 117
M  V30 117 1 110 118
M  V30 118 1 111 119
M  V30 119 1 112 120
M  V30 120 1 113 121
M  V30 121 1 114 122
M  V30 122 1 115 123
M  V30 123 1 116 124
M  V30 124 1 117 125
M  V30 125 1 118 126
M  V30 126 1 119 127
M  V30 127 1 120 128
M  V30 128 1 121 129
M  V30 129 1 122 130
M  V30 130 1 123 131
M  V30 131 1 124 132
M  V30 132 1 124 133
M  V30 133 1 125 134
M  V30 134 1 125 135
M  V30 135 1 126 136
M  V30 136 1 126 137
M  V30 137 1 127 138
M  V30 138 1 128 139
M  V30 139 1 129 140
M  V30 140 1 131 141
M  V30 141 1 132 142
M  V30 142 1 133 143
M  V30 143 1 134 144
M  V30 144 1 135 145
M  V30 145 1 136 146
M  V30 146 1 137 147
M  V30 147 1 138 148
M  V30 148 1 139 149
M  V30 149 1 140 150
M  V30 150 1 141 151
M  V30 151 1 142 152
M  V30 152 1 143 153
M  V30 153 1 144 154
M  V30 154 1 145 155
M  V30 155 1 146 156
M  V30 156 1 147 157
M  V30 157 1 148 158
M  V30 158 1 149 159
M  V30 159 1 150 160
M  V30 160 1 151 161
M  V30 161 1 152 162
M  V30 162 1 153 163
M  V30 163 1 153 164
M  V30 164 1 154 165
M  V30 165 1 155 166
M  V30 166 1 155 167
M  V30 167 1 156 168
M  V30 168 1 157 169
M  V30 169 1 157 170
M  V30 170 1 158 171
M  V30 171 1 159 172
M  V30 172 1 160 173
M  V30 173 1 161 174
M  V30 174 1 162 175
M  V30 175 1 163 176
M  V30 176 1 164 177
M  V30 177 1 165 178
M  V30 178 1 166 179
M  V30 179 1 167 180
M  V30 180 1 169 181
M  V30 181 1 170 182
M  V30 182 1 171 183
M  V30 183 1 172 184
M  V30 184 1 173 185
M  V30 185 1 174 186
M  V30 186 1 175 187
M  V30 187 1 176 188
M  V30 188 1 177 189
M  V30 189 1 178 190
M  V30 190 1 179 191
M  V30 191 1 180 192
M  V30 192 1 181 193
M  V30 193 1 182 194
M  V30 194 1 183 195
M  V30 195 1 184 196
M  V30 196 1 185 197
M  V30 197 1 186 198
M  V30 198 1 187 199
M  V30 199 1 188 200
M  V30 200 1 189 201
M  V30 201 1 189 202
M  V30 202 1 190 203
M  V30 203 1 191 204
M  V30 204 1 192 205
M  V30 205 1 193 206
M  V30 206 1 194 207
M  V30 207 1 195 208
M  V30 208 1 196 209
M  V30 209 1 197 210
M  V30 210 1 198 211
M  V30 211 1 199 212
M  V30 212 1 200 213
M  V30 213 1 201 214
M  V30 214 1 202 215
M  V30 215 1 203 216
M  V30 216 1 204 217
M  V30 217 1 206 218
M  V30 218 1 207 219
M  V30 219 1 208 220
M  V30 220 1 209 221
M  V30 221 1 210 222
M  V30 222 1 211 223
M  V30 223 1 212 224
M  V30 224 1 213 225
M  V30 225 1 214 226
M  V30 226 1 215 227
M  V30 227 1 216 228
M  V30 228 1 217 229
M  V30 229 1 218 230
M  V30 230 1 219 231
M  V30 231 1 220 232
M  V30 232 1 221 233
M  V30 233 1 222 234
M  V30 234 1 223 235
M  V30 235 1 224 236
M  V30 236 1 225 237
M  V30 237 1 226 238
M  V30 238 1 227 239
M  V30 239 1 228 240
M  V30 240 1 229 241
M  V30 241 1 230 242
M  V30 242 1 231 243
M  V30 243 1 232 244
M  V30 244 1 233 245
M  V30 245 1 234 246
M  V30 246 1 235 247
M  V30 247 1 236 248
M  V30 248 1 237 249
M  V30 249 1 238 250
M  V30 250 1 240 251
M  V30 251 1 241 252
M  V30 252 1 242 253
M  V30 253 1 243 254
M  V30 254 1 244 255
M  V30 255 1 245 256
M  V30 256 1 246 257
M  V30 257 1 247 258
M  V30 258 1 248 259
M  V30 259 1 249 260
M  V30 260 1 250 261
M  V30 261 1 251 262
M  V30 262 1 252 263
M  V30 263 1 253 264
M  V30 264 1 254 265
M  V30 265 1 255 266
M  V30 266 1 256 267
M  V30 267 1 257 268
M  V30 268 1 258 269
M  V30 269 1 259 270
M  V30 270 1 260 271
M  V30 271 1 261 272
M  V30 272 1 262 273
M  V30 273 1 263 274
M  V30 274 1 264 275
M  V30 275 1 265 276
M  V30 276 1 266 277
M  V30 277 1 267 278
M  V30 278 1 268 279
M  V30 279 1 269 280
M  V30 280 1 270 281
M  V30 281 1 271 282
M  V30 282 1 272 283
M  V30 283 1 273 284
M  V30 284 1 274 285
M  V30 285 1 275 286
M  V30 286 1 276 287
M  V30 287 1 277 288
M  V30 288 1 278 289
M  V30 289 1 279 290
M  V30 290 1 280 291
M  V30 291 1 281 292
M  V30 292 1 282 293
M  V30 293 1 283 294
M  V30 294 1 284 295
M  V30 295 1 285 296
M  V30 296 1 286 297
M  V30 297 1 287 298
M  V30 298 1 288 299
M  V30 299 1 289 300
M  V30 300 1 290 301
M  V30 301 1 291 302
M  V30 302 1 292 303
M  V30 303 1 293 304
M  V30 304 1 294 305
M  V30 305 1 295 306
M  V30 306 1 296 307
M  V30 307 1 297 308
M  V30 308 1 298 309
M  V30 309 1 299 310
M  V30 310 1 300 311
M  V30 311 1 301 312
M  V30 312 1 302 313
M  V30 313 1 303 314
M  V30 314 1 304 315
M  V30 315 1 305 316
M  V30 316 1 306 317
M  V30 317 1 307 318
M  V30 318 1 308 319
M  V30 319 1 309 320
M  V30 320 1 310 321
M  V30 321 1 311 322
M  V30 322 1 312 323
M  V30 323 1 313 324
M  V30 324 1 314 325
M  V30 325 1 315 326
M  V30 326 1 316 327
M  V30 327 1 317 328
M  V30 328 1 318 329
M  V30 329 1 319 330
M  V30 330 1 320 331
M  V30 331 1 321 332
M  V30 332 1 322 333
M  V30 333 1 323 334
M  V30 334 1 324 335
M  V30 335 1 325 336
M  V30 336 1 326 337
M  V30 337 1 327 338
M  V30 338 1 328 339
M  V30 339 1 329 340
M  V30 340 1 330 341
M  V30 341 1 331 342
M  V30 342 1 332 343
M  V30 343 1 333 344
M  V30 344 1 334 345
M  V30 345 1 335 346
M  V30 346 1 336 347
M  V30 347 1 337 348
M  V30 348 1 338 349
M  V30 349 1 339 350
M  V30 350 1 340 351
M  V30 351 1 341 352
M  V30 352 1 342 353
M  V30 353 1 343 354
M  V30 354 1 344 355
M  V30 355 1 345 356
M  V30 356 1 346 357
M  V30 357 1 347 358
M  V30 358 1 348 359
M  V30 359 1 349 360
M  V30 360 1 350 361
M  V30 361 1 351 362
M  V30 362 1 352 363
M  V30 363 1 353 364
M  V30 364 1 354 365
M  V30 365 1 355 366
M  V30 366 1 356 367
M  V30 367 1 357 368
M  V30 368 1 358 369
M  V30 369 1 359 370
M  V30 370 1 360 371
M  V30 371 1 361 372
M  V30 372 1 362 373
M  V30 373 1 363 374
M  V30 374 1 364 375
M  V30 375 1 365 376
M  V30 376 1 366 377
M  V30 377 1 367 378
M  V30 378 1 368 379
M  V30 379 1 369 380
M  V30 380 1 370 381
M  V30 381 1 371 382
M  V30 382 1 372 383
M  V30 383 1 373 384
M  V30 384 1 374 385
M  V30 385 1 375 386
M  V30 386 1 376 387
M  V30 387 1 377 388
M  V30 388 1 378 389
M  V30 389 1 379 390
M  V30 390 1 380 391
M  V30 391 1 381 392
M  V30 392 1 382 393
M  V30 393 1 383 394
M  V30 394 1 384 395
M  V30 395 1 385 396
M  V30 396 1 386 397
M  V30 397 1 387 398
M  V30 398 1 388 399
M  V30 399 1 389 400
M  V30 400 1 390 401
M  V30 401 1 391 402
M  V30 402 1 392 403
M  V30 403 1 393 404
M  V30 404 1 394 405
M  V30 405 1 395 406
M  V30 406 1 396 407
M  V30 407 1 397 408
M  V30 408 1 398 409
M  V30 409 1 399 410
M  V30 410 1 400 411
M  V30 411 1 401 412
M  V30 412 1 402 413
M  V30 413 1 403 414
M  V30 414 1 404 415
M  V30 415 1 405 416
M  V30 416 1 406 417
M  V30 417 1 407 418
M  V30 418 1 408 419
M  V30 419 1 409 420
M  V30 420 1 410 421
M  V30 421 1 411 422
M  V30 422 1 412 423
M  V30 423 1 413 424
M  V30 424 1 414 425
M  V30 425 1 415 426
M  V30 426 1 416 427
M  V30 427 1 417 428
M  V30 428 1 418 429
M  V30 429 1 419 430
M  V30 430 1 420 431
M  V30 431 1 421 432
M  V30 432 1 422 433
M  V30 433 1 423 434
M  V30 434 1 424 435
M  V30 435 1 425 436
M  V30 436 1 426 437
M  V30 437 1 427 438
M  V30 438 1 428 439
M  V30 439 1 429 440
M  V30 440 1 430 441
M  V30 441 1 431 442
M  V30 442 1 432 443
M  V30 443 1 433 444
M  V30 444 1 434 445
M  V30 445 1 435 446
M  V30 446 1 436 447
M  V30 447 1 437 448
M  V30 448 1 438 449
M  V30 449 1 439 450
M  V30 450 1 440 451
M  V30 451 1 441 452
M  V30 452 1 442 453
M  V30 453 1 443 454
M  V30 454 1 444 455
M  V30 455 1 445 456
M  V30 456 1 446 457
M  V30 457 1 447 458
M  V30 458 1 448 459
M  V30 459 1 449 460
M  V30 460 1 450 461
M  V30 461 1 451 462
M  V30 462 1 452 463
M  V30 463 1 453 464
M  V30 464 1 454 465
M  V30 465 1 455 466
M  V30 466 1 456 467
M  V30 467 1 457 468
M  V30 468 1 458 469
M  V30 469 1 459 470
M  V30 470 1 460 471
M  V30 471 1 461 472
M  V30 472 1 462 473
M  V30 473 1 463 474
M  V30 474 1 464 475
M  V30 475 1 465 476
M  V30 476 1 466 477
M  V30 477 1 467 478
M  V30 478 1 468 479
M  V30 479 1 469 480
M  V30 480 1 470 481
M  V30 481 1 471 482
M  V30 482 1 472 483
M  V30 483 1 473 484
M  V30 484 1 474 485
M  V30 485 1 475 486
M  V30 486 1 476 487
M  V30 487 1 477 488
M  V30 488 1 478 489
M  V30 489 1 479 490
M  V30 490 1 480 491
M  V30 491 1 481 492
M  V30 492 1 482 493
M  V30 493 1 483 494
M  V30 494 1 484 495
M  V30 495 1 485 496
M  V30 496 1 486 497
M  V30 497 1 487 498
M  V30 498 1 488 499
M  V30 499 1 489 500
M  V30 500 1 490 501
M  V30 501 1 491 502
M  V30 502 1 492 503
M  V30 503 1 493 504
M  V30 504 1 494 505
M  V30 505 1 495 506
M  V30 506 1 496 507
M  V30 507 1 497 508
M  V30 508 1 498 509
M  V30 509 1 499 510
M  V30 510 1 500 511
M  V30 511 1 501 512
M  V30 512 1 502 513
M  V30 513 1 503 514
M  V30 514 1 504 515
M  V30 515 1 505 516
M  V30 516 1 506 517
M  V30 517 1 507 518
M  V30 518 1 508 519
M  V30 519 1 509 520
M  V30 520 1 510 521
M  V30 521 1 511 522
M  V30 522 1 512 523
M  V30 523 1 513 524
M  V30 524 1 514 525
M  V30 525 1 515 526
M  V30 526 1 516 527
M  V30 527 1 517 528
M  V30 528 1 518 529
M  V30 529 1 519 530
M  V30 530 1 520 531
M  V30 531 1 521 532
M  V30 532 1 522 533
M  V30 533 1 523 534
M  V30 534 1 524 535
M  V30 535 1 525 536
M  V30 536 1 526 537
M  V30 537 1 527 538
M  V30 538 1 528 539
M  V30 539 1 529 540
M  V30 540 1 530 541
M  V30 541 1 531 542
M  V30 542 1 532 543
M  V30 543 1 533 544
M  V30 544 1 534 545
M  V30 545 1 535 546
M  V30 546 1 536 547
M  V30 547 1 537 548
M  V30 548 1 538 549
M  V30 549 1 539 550
M  V30 550 1 540 551
M  V30 551 1 541 552
M  V30 552 1 542 553
M  V30 553 1 543 554
M  V30 554 1 544 555
M  V30 555 1 545 556
M  V30 556 1 546 557
M  V30 557 1 547 558
M  V30 558 1 548 559
M  V30 559 1 549 560
M  V30 560 1 550 561
M  V30 561 1 551 562
M  V30 562 1 552 563
M  V30 563 1 553 564
M  V30 564 1 554 565
M  V30 565 1 555 566
M  V30 566 1 556 567
M  V30 567 1 557 568
M  V30 568 1 558 569
M  V30 569 1 559 570
M  V30 570 1 560 571
M  V30 571 1 561 572
M  V30 572 1 562 573
M  V30 573 1 563 574
M  V30 574 1 564 575
M  V30 575 1 565 576
M  V30 576 1 566 577
M  V30 577 1 567 578
M  V30 578 1 568 579
M  V30 579 1 569 580
M  V30 580 1 570 581
M  V30 581 1 571 582
M  V30 582 1 572 583
M  V30 583 1 573 584
M  V30 584 1 574 585
M  V30 585 1 575 586
M  V30 586 1 576 587
M  V30 587 1 577 588
M  V30 588 1 578 589
M  V30 589 1 579 590
M  V30 590 1 580 591
M  V30 591 1 581 592
M  V30 592 1 582 593
M  V30 593 1 583 594
M  V30 594 1 584 595
M  V30 595 1 585 596
M  V30 596 1 586 597
M  V30 597 1 587 598
M  V30 598 1 588 599
M  V30 599 1 589 600
M  V30 600 1 590 601
M  V30 601 1 591 602
M  V30 602 1 592 603
M  V30 603 1 593 604
M  V30 604 1 594 605
M  V30 605 1 595 606
M  V30 606 1 596 607
M  V30 607 1 597 608
M  V30 608 1 598 609
M  V30 609 1 599 610
M  V30 610 1 600 611
M  V30 611 1 601 612
M  V30 612 1 602 613
M  V30 613 1 603 614
M  V30 614 1 604 615
M  V30 615 1 605 616
M  V30 616 1 606 617
M  V30 617 1 607 618
M  V30 618 1 608 619
M  V30 619 1 609 620
M  V30 620 1 610 621
M  V30 621 1 611 622
M  V30 622 1 612 623
M  V30 623 1 613 624
M  V30 624 1 614 625
M  V30 625 1 615 626
M  V30 626 1 616 627
M  V30 627 1 617 628
M  V30 628 1 618 629
M  V30 629 1 619 630
M  V30 630 1 620 631
M  V30 631 1 621 632
M  V30 632 1 622 633
M  V30 633 1 623 634
M  V30 634 1 624 635
M  V30 635 1 625 636
M  V30 636 1 626 637
M  V30 637 1 627 638
M  V30 638 1 628 639
M  V30 639 1 630 640
M  V30 640 1 631 641
M  V30 641 1 632 642
M  V30 642 1 633 643
M  V30 643 1 634 644
M  V30 644 1 635 645
M  V30 645 1 636 646
M  V30 646 1 637 647
M  V30 647 1 638 648
M  V30 648 1 639 649
M  V30 649 1 640 650
M  V30 650 1 641 651
M  V30 651 1 642 652
M  V30 652 1 643 653
M  V30 653 1 644 654
M  V30 654 1 645 655
M  V30 655 1 646 656
M  V30 656 1 647 657
M  V30 657 1 648 658
M  V30 658 1 649 659
M  V30 659 1 650 660
M  V30 660 1 651 661
M  V30 661 1 652 662
M  V30 662 1 653 663
M  V30 663 1 654 664
M  V30 664 1 655 665
M  V30 665 1 656 666
M  V30 666 1 657 667
M  V30 667 1 658 668
M  V30 668 1 659 669
M  V30 669 1 660 670
M  V30 670 1 661 671
M  V30 671 1 662 672
M  V30 672 1 663 673
M  V30 673 1 664 674
M  V30 674 1 665 675
M  V30 675 1 666 676
M  V30 676 1 667 677
M  V30 677 1 668 678
M  V30 678 1 669 679
M  V30 679 1 670 680
M  V30 680 1 671 681
M  V30 681 1 672 682
M  V30 682 1 673 683
M  V30 683 1 674 684
M  V30 684 1 675 685
M  V30 685 1 676 686
M  V30 686 1 677 687
M  V30 687 1 678 688
M  V30 688 1 679 689
M  V30 689 1 680 690
M  V30 690 1 681 691
M  V30 691 1 682 692
M  V30 692 1 683 693
M  V30 693 1 684 694
M  V30 694 1 685 695
M  V30 695 1 686 696
M  V30 696 1 687 697
M  V30 697 1 688 698
M  V30 698 1 689 699
M  V30 699 1 690 700
M  V30 700 1 691 701
M  V30 701 1 692 702
M  V30 702 1 693 703
M  V30 703 1 694 704
M  V30 704 1 695 705
M  V30 705 1 696 706
M  V30 706 1 697 707
M  V30 707 1 698 708
M  V30 708 1 699 709
M  V30 709 1 700 710
M  V30 710 1 701 711
M  V30 711 1 702 712
M  V30 712 1 703 713
M  V30 713 1 704 714
M  V30 714 1 705 715
M  V30 715 1 706 716
M  V30 716 1 707 717
M  V30 717 1 708 718
M  V30 718 1 709 719
M  V30 719 1 710 720
M  V30 720 1 711 721
M  V30 721 1 712 722
M  V30 722 1 713 723
M  V30 723 1 714 724
M  V30 724 1 715 725
M  V30 725 1 716 726
M  V30 726 1 717 727
M  V30 727 1 718 728
M  V30 728 1 719 729
M  V30 729 1 721 730
M  V30 730 1 722 731
M  V30 731 1 723 732
M  V30 732 1 724 733
M  V30 733 1 725 734
M  V30 734 1 726 735
M  V30 735 1 727 736
M  V30 736 1 728 737
M  V30 737 1 729 738
M  V30 738 1 730 739
M  V30 739 1 731 740
M  V30 740 1 732 741
M  V30 741 1 733 742
M  V30 742 1 734 743
M  V30 743 1 735 744
M  V30 744 1 736 745
M  V30 745 1 737 746
M  V30 746 1 738 747
M  V30 747 1 739 748
M  V30 748 1 740 749
M  V30 749 1 741 750
M  V30 750 1 742 751
M  V30 751 1 743 752
M  V30 752 1 744 753
M  V30 753 1 745 754
M  V30 754 1 746 755
M  V30 755 1 747 756
M  V30 756 1 750 757
M  V30 757 1 751 758
M  V30 758 1 752 759
M  V30 759 1 753 760
M  V30 760 1 754 761
M  V30 761 1 755 762
M  V30 762 1 756 763
M  V30 763 1 757 764
M  V30 764 1 758 765
M  V30 765 1 759 766
M  V30 766 1 760 767
M  V30 767 1 761 768
M  V30 768 1 762 769
M  V30 769 1 763 770
M  V30 770 1 764 771
M  V30 771 1 765 772
M  V30 772 1 766 773
M  V30 773 1 767 774
M  V30 774 1 768 775
M  V30 775 1 769 776
M  V30 776 1 770 777
M  V30 777 1 772 778
M  V30 778 1 773 779
M  V30 779 1 775 780
M  V30 780 1 776 781
M  V30 781 1 777 782
M  V30 782 1 778 783
M  V30 783 1 779 784
M  V30 784 1 780 785
M  V30 785 1 781 786
M  V30 786 1 782 787
M  V30 787 1 783 788
M  V30 788 1 784 789
M  V30 789 1 785 790
M  V30 790 1 786 791
M  V30 791 1 787 792
M  V30 792 1 789 793
M  V30 793 1 793 794
M  V30 794 1 794 795
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000726A1-20220106-C00004

>  <Row No>
505

$$$$
US20220000726A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C 1.262 -0.6934 0.0 0
M  V30 3 C -1.3452 -0.6934 0.0 0
M  V30 4 C -0.7766 1.3452 0.0 0
M  V30 5 C 2.524 0.0832 0.0 0
M  V30 6 C -2.6905 0.0832 0.0 0
M  V30 7 C -0.0832 2.6905 0.0 0
M  V30 8 N 3.7861 -0.6102 0.0 0
M  V30 9 N -4.0357 -0.6102 0.0 0
M  V30 10 N -0.8598 4.0357 0.0 0
M  V30 11 C 5.0481 0.1664 0.0 0
M  V30 12 C -5.381 0.1664 0.0 0
M  V30 13 C -0.0554 5.381 0.0 0
M  V30 14 C 6.3102 -0.527 0.0 0
M  V30 15 N 7.5722 0.2496 0.0 0
M  V30 16 C 8.8343 -0.4437 0.0 0
M  V30 17 C 10.0963 0.3328 0.0 0
M  V30 18 C 11.3584 -0.3605 0.0 0
M  V30 19 N 12.6204 0.416 0.0 0
M  V30 20 C 12.3292 -0.8459 0.0 0
M  V30 21 C 14.3679 1.1927 0.0 0
M  V30 22 C 13.0226 -2.108 0.0 0
M  V30 23 C 15.63 0.4992 0.0 0
M  V30 24 N 12.246 -3.37 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000726A1-20220106-C00005

>  <Row No>
506

$$$$
US20220000726A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 65 57 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0226 -1.2704 0.0 0
M  V30 3 O -1.4293 -1.2478 0.0 0
M  V30 4 C 0.2268 -0.6352 0.0 0
M  V30 5 C -3.3804 -1.2251 0.0 0
M  V30 6 C 0.794 -1.6788 0.0 0
M  V30 7 C -5.0365 -1.2024 0.0 0
M  V30 8 C 2.0191 -1.6108 0.0 0
M  V30 9 O -6.3978 -1.1797 0.0 0
M  V30 10 C 3.4938 -0.9755 0.0 0
M  V30 11 C -7.8044 -1.157 0.0 0
M  V30 12 C 5.218 -0.9074 0.0 0
M  V30 13 C -7.8271 -3.5846 0.0 0
M  V30 14 C -7.8725 1.3612 0.0 0
M  V30 15 C 6.9423 -0.8394 0.0 0
M  V30 16 O -6.4658 -3.5619 0.0 0
M  V30 17 O -6.5566 1.4293 0.0 0
M  V30 18 C 8.6665 -0.7713 0.0 0
M  V30 19 C -5.15 -3.5392 0.0 0
M  V30 20 C -5.2861 1.4973 0.0 0
M  V30 21 O 9.506 -1.6108 0.0 0
M  V30 22 C 9.2791 -0.1361 0.0 0
M  V30 23 C -3.5392 -3.5165 0.0 0
M  V30 24 C -3.7207 1.5654 0.0 0
M  V30 25 ? 10.6857 -1.2024 0.0 0
M  V30 26 C 9.8463 -1.1797 0.0 0
M  V30 27 O -1.6334 -3.4938 0.0 0
M  V30 28 O -1.8603 1.6334 0.0 0
M  V30 29 C 11.0714 -1.1116 0.0 0
M  V30 30 C -0.2722 -3.4711 0.0 0
M  V30 31 C -0.5444 1.7015 0.0 0
M  V30 32 C 12.5461 -0.4764 0.0 0
M  V30 33 O -0.3403 -2.1099 0.0 0
M  V30 34 C 0.6806 -4.0156 0.0 0
M  V30 35 O -0.6125 3.0627 0.0 0
M  V30 36 C 0.9528 0.794 0.0 0
M  V30 37 C 1.2931 -2.8812 0.0 0
M  V30 38 C 3.4711 -3.4257 0.0 0
M  V30 39 C 5.2407 -3.4031 0.0 0
M  V30 40 C 7.0103 -3.3804 0.0 0
M  V30 41 C 8.78 -3.3577 0.0 0
M  V30 42 O 9.6648 -4.2425 0.0 0
M  V30 43 C 9.3925 -2.7224 0.0 0
M  V30 44 ? 10.8899 -3.8795 0.0 0
M  V30 45 C 9.9597 -3.7661 0.0 0
M  V30 46 C 11.1848 -3.698 0.0 0
M  V30 47 C 12.6595 -3.0627 0.0 0
M  V30 48 O 10.1639 0.5444 0.0 0
M  V30 49 C 9.1883 1.52 0.0 0
M  V30 50 ? 11.389 0.9074 0.0 0
M  V30 51 C 7.328 1.5881 0.0 0
M  V30 52 C 9.8009 2.1552 0.0 0
M  V30 53 C 5.4676 1.6561 0.0 0
M  V30 54 C 10.3681 1.1116 0.0 0
M  V30 55 C 3.6072 1.7242 0.0 0
M  V30 56 C 11.5932 1.1797 0.0 0
M  V30 57 C 0.7033 2.7678 0.0 0
M  V30 58 C 13.0679 1.8149 0.0 0
M  V30 59 C -0.4764 2.2006 0.0 0
M  V30 60 C -7.0784 1.2704 0.0 0
M  V30 61 C -7.0784 -1.2704 0.0 0
M  V30 62 C -7.0784 -3.6299 0.0 0
M  V30 63 C -2.3594 1.2704 0.0 0
M  V30 64 C -2.3594 -1.2704 0.0 0
M  V30 65 C -2.3594 -3.6299 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 23 27
M  V30 27 1 24 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 28 31
M  V30 31 1 29 32
M  V30 32 2 30 33
M  V30 33 1 30 34
M  V30 34 2 31 35
M  V30 35 1 31 36
M  V30 36 1 34 37
M  V30 37 1 37 38
M  V30 38 1 38 39
M  V30 39 1 39 40
M  V30 40 1 40 41
M  V30 41 1 41 42
M  V30 42 1 41 43
M  V30 43 1 42 44
M  V30 44 1 43 45
M  V30 45 1 45 46
M  V30 46 1 46 47
M  V30 47 1 48 49
M  V30 48 1 48 50
M  V30 49 1 49 51
M  V30 50 1 49 52
M  V30 51 1 51 53
M  V30 52 1 52 54
M  V30 53 1 53 55
M  V30 54 1 54 56
M  V30 55 1 55 57
M  V30 56 1 56 58
M  V30 57 1 57 59
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000726A1-20220106-C00006

>  <Row No>
507

$$$$
US20220000726A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000726A1-20220106-C00007

>  <Row No>
508

$$$$
US20220000726A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 64 62 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.039 -1.4697 0.0 0
M  V30 3 C -1.2876 -2.3022 0.0 0
M  V30 4 C 1.1316 -2.3022 0.0 0
M  V30 5 C -0.8584 -3.6939 0.0 0
M  V30 6 C -2.6274 -1.4958 0.0 0
M  V30 7 C 0.6243 -3.6939 0.0 0
M  V30 8 C -3.9671 -2.2241 0.0 0
M  V30 9 C -5.3068 -1.4177 0.0 0
M  V30 10 C -6.6465 -2.1461 0.0 0
M  V30 11 C -5.3458 0.13 0.0 0
M  V30 12 C -6.6855 -3.6159 0.0 0
M  V30 13 C -5.4239 -4.3443 0.0 0
M  V30 14 C -5.4629 -5.8141 0.0 0
M  V30 15 C -4.2012 -6.5425 0.0 0
M  V30 16 C -6.8026 -6.5425 0.0 0
M  V30 17 O -0.2081 7.492 0.0 0
M  V30 18 C -1.7039 7.1278 0.0 0
M  V30 19 C -3.0436 6.3994 0.0 0
M  V30 20 C -1.7429 8.6756 0.0 0
M  V30 21 C -0.4422 6.3994 0.0 0
M  V30 22 C -3.0826 4.9296 0.0 0
M  V30 23 C -3.0826 9.482 0.0 0
M  V30 24 C -4.4223 8.7537 0.0 0
M  V30 25 C -5.762 9.5601 0.0 0
M  V30 26 C -7.1018 8.8317 0.0 0
M  V30 27 C -5.8011 11.1079 0.0 0
M  V30 28 C -7.1408 7.3619 0.0 0
M  V30 29 C -5.8791 6.6335 0.0 0
M  V30 30 C -5.9181 5.1637 0.0 0
M  V30 31 C -4.6565 4.4353 0.0 0
M  V30 32 C -7.2579 4.4353 0.0 0
M  V30 33 O -13.3191 0.0 0.0 0
M  V30 34 C -14.4117 -1.0145 0.0 0
M  V30 35 C -13.15 -1.7429 0.0 0
M  V30 36 C -15.7514 -1.7429 0.0 0
M  V30 37 C -15.5043 0.078 0.0 0
M  V30 38 C -13.189 -3.2127 0.0 0
M  V30 39 C -11.8883 -0.9365 0.0 0
M  V30 40 C -15.7904 -3.2127 0.0 0
M  V30 41 C -11.9274 -3.9411 0.0 0
M  V30 42 C -10.6267 -1.6648 0.0 0
M  V30 43 C -14.5288 -3.9411 0.0 0
M  V30 44 C -10.6657 -3.1346 0.0 0
M  V30 45 C -14.5678 -5.4109 0.0 0
M  V30 46 C -9.404 -3.863 0.0 0
M  V30 47 C -13.3061 -6.1392 0.0 0
M  V30 48 C -15.9075 -6.1392 0.0 0
M  V30 49 O -10.4055 4.2662 0.0 0
M  V30 50 C -11.7453 5.0727 0.0 0
M  V30 51 C -11.7843 6.6205 0.0 0
M  V30 52 C -10.5226 7.4269 0.0 0
M  V30 53 C -10.5616 8.9748 0.0 0
M  V30 54 C -9.2609 6.6986 0.0 0
M  V30 55 C -11.9013 9.7812 0.0 0
M  V30 56 C -13.2411 9.0528 0.0 0
M  V30 57 C -14.5808 9.8592 0.0 0
M  V30 58 C -15.9205 9.1309 0.0 0
M  V30 59 C -14.6198 11.4071 0.0 0
M  V30 60 C -15.9595 7.6611 0.0 0
M  V30 61 C -14.6978 6.9327 0.0 0
M  V30 62 C -14.7369 5.4629 0.0 0
M  V30 63 C -13.4752 4.7345 0.0 0
M  V30 64 C -16.0766 4.7345 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 6 8
M  V30 8 2 8 9
M  V30 9 1 9 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 17 18
M  V30 17 1 18 19
M  V30 18 1 18 20
M  V30 19 1 18 21
M  V30 20 2 19 22
M  V30 21 1 20 23
M  V30 22 1 23 24
M  V30 23 2 24 25
M  V30 24 1 25 26
M  V30 25 1 25 27
M  V30 26 1 26 28
M  V30 27 1 28 29
M  V30 28 2 29 30
M  V30 29 1 30 31
M  V30 30 1 30 32
M  V30 31 1 33 34
M  V30 32 1 34 35
M  V30 33 1 34 36
M  V30 34 1 34 37
M  V30 35 1 35 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 1 38 41
M  V30 39 1 39 42
M  V30 40 1 40 43
M  V30 41 2 41 44
M  V30 42 2 43 45
M  V30 43 1 44 46
M  V30 44 1 45 47
M  V30 45 1 45 48
M  V30 46 1 49 50
M  V30 47 1 50 51
M  V30 48 2 51 52
M  V30 49 1 52 53
M  V30 50 1 52 54
M  V30 51 1 53 55
M  V30 52 1 55 56
M  V30 53 2 56 57
M  V30 54 1 57 58
M  V30 55 1 57 59
M  V30 56 1 58 60
M  V30 57 1 60 61
M  V30 58 2 61 62
M  V30 59 1 62 63
M  V30 60 1 62 64
M  V30 61 1 5 7
M  V30 62 1 42 44
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000726A1-20220106-C00008

>  <Row No>
509

$$$$
US20220000726A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000726A1-20220106-C00009

>  <Row No>
510

$$$$
US20220000726A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000726A1-20220106-C00010

>  <Row No>
511

$$$$
US20220000729A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Ra 0.0 0.0 0.0 0 VAL=2
M  V30 2 O -0.0408 -1.6627 0.0 0
M  V30 3 C -0.0817 -1.9353 0.0 0
M  V30 4 Si -0.1226 -3.598 0.0 0
M  V30 5 O 1.54 -3.5571 0.0 0
M  V30 6 O -0.1635 -5.2607 0.0 0
M  V30 7 O -1.8671 -3.5571 0.0 0 CHG=-1
M  V30 8 C 3.2027 -3.5162 0.0 0
M  V30 9 C -0.2044 -6.9234 0.0 0
M  V30 10 Rb -3.816 -3.489 0.0 0 CHG=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 4 1 4 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000729A1-20220106-C00001

>  <Row No>
512

$$$$
US20220000729A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Ra 0.0 0.0 0.0 0 VAL=2
M  V30 2 O -0.0408 -1.6627 0.0 0
M  V30 3 C -0.0817 -1.9353 0.0 0
M  V30 4 Si -0.1226 -3.598 0.0 0
M  V30 5 O 1.54 -3.5571 0.0 0
M  V30 6 O -0.1635 -5.2607 0.0 0
M  V30 7 O -1.8671 -3.5571 0.0 0 CHG=-1
M  V30 8 C 3.2027 -3.5162 0.0 0
M  V30 9 C -0.2044 -6.9234 0.0 0
M  V30 10 Rb -3.816 -3.489 0.0 0 CHG=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 4 1 4 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000729A1-20220106-C00002

>  <Row No>
513

$$$$
US20220000729A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.6295 0.04 0.0 0
M  V30 3 O -1.7096 0.04 0.0 0
M  V30 4 O -0.04 -1.6295 0.0 0
M  V30 5 C -0.04 1.7096 0.0 0
M  V30 6 C 3.259 0.0801 0.0 0
M  V30 7 C -3.4193 0.0801 0.0 0
M  V30 8 C -0.0801 -3.259 0.0 0
M  V30 9 C -0.0801 2.0569 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000729A1-20220106-C00003

>  <Row No>
514

$$$$
US20220000729A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 143 133 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.2095 -0.8639 0.0 0
M  V30 3 O 1.0943 -0.5759 0.0 0
M  V30 4 O 0.8639 1.2095 0.0 0
M  V30 5 C -1.4398 0.9215 0.0 0
M  V30 6 C -0.3455 -1.7278 0.0 0
M  V30 7 C 2.1886 0.3455 0.0 0
M  V30 8 C -0.3455 2.419 0.0 0
M  V30 9 C -2.8797 0.3455 0.0 0
M  V30 10 C 0.8639 -1.1519 0.0 0
M  V30 11 C 3.2829 -0.2303 0.0 0
M  V30 12 C 0.2303 3.8589 0.0 0
M  V30 13 C -4.3196 1.2671 0.0 0
M  V30 14 C -5.7595 0.6911 0.0 0
M  V30 15 C -7.1994 1.6126 0.0 0
M  V30 16 C -8.6393 1.0367 0.0 0
M  V30 17 C -10.0792 1.9582 0.0 0
M  V30 18 C -11.5191 1.3822 0.0 0
M  V30 19 C -12.9589 2.3038 0.0 0
M  V30 20 C -14.3988 1.7278 0.0 0
M  V30 21 C -15.8387 2.6493 0.0 0
M  V30 22 C -17.2786 2.0734 0.0 0
M  V30 23 Si -4.6076 17.509 0.0 0
M  V30 24 O -3.7437 18.7185 0.0 0
M  V30 25 O -3.5133 16.933 0.0 0
M  V30 26 O -5.8171 16.6451 0.0 0
M  V30 27 C -6.0475 18.4305 0.0 0
M  V30 28 C -4.9532 19.928 0.0 0
M  V30 29 C -2.419 17.8546 0.0 0
M  V30 30 C -4.9532 15.7811 0.0 0
M  V30 31 C -7.4874 17.8546 0.0 0
M  V30 32 C -4.0892 21.1375 0.0 0
M  V30 33 C -1.3246 17.2786 0.0 0
M  V30 34 C -3.6861 16.3571 0.0 0
M  V30 35 C -8.9273 18.7761 0.0 0
M  V30 36 C -10.3671 18.2001 0.0 0
M  V30 37 C -11.807 19.1217 0.0 0
M  V30 38 C -13.2469 18.5457 0.0 0
M  V30 39 C -14.6868 19.4672 0.0 0
M  V30 40 C -16.1267 18.8913 0.0 0
M  V30 41 Si -7.3722 32.7142 0.0 0
M  V30 42 O -6.5082 33.9237 0.0 0
M  V30 43 O -6.2779 32.1383 0.0 0
M  V30 44 O -8.5817 31.8503 0.0 0
M  V30 45 C -8.8121 33.6357 0.0 0
M  V30 46 C -7.7178 35.1332 0.0 0
M  V30 47 C -5.1835 33.0598 0.0 0
M  V30 48 C -7.7178 30.9863 0.0 0
M  V30 49 C -10.252 33.0598 0.0 0
M  V30 50 C -6.8538 36.3427 0.0 0
M  V30 51 C -4.0892 32.4838 0.0 0
M  V30 52 C -6.4507 31.5623 0.0 0
M  V30 53 C -11.6918 33.9813 0.0 0
M  V30 54 C -13.1317 33.4054 0.0 0
M  V30 55 C -14.5716 34.3269 0.0 0
M  V30 56 C -16.0115 33.7509 0.0 0
M  V30 57 Si -2.3038 9.676 0.0 0
M  V30 58 O -1.4974 10.8279 0.0 0
M  V30 59 O -3.4557 8.8697 0.0 0
M  V30 60 O -1.2671 9.1576 0.0 0
M  V30 61 C -3.6861 10.5399 0.0 0
M  V30 62 C -2.6493 11.9798 0.0 0
M  V30 63 C -2.6493 8.0633 0.0 0
M  V30 64 C -0.2303 10.0216 0.0 0
M  V30 65 C -5.0684 10.0216 0.0 0
M  V30 66 C -6.4507 10.8855 0.0 0
M  V30 67 C -7.8329 10.3671 0.0 0
M  V30 68 C -9.2152 11.2311 0.0 0
M  V30 69 C -10.5975 10.7127 0.0 0
M  V30 70 C -11.9798 11.5767 0.0 0
M  V30 71 C -13.3621 11.0583 0.0 0
M  V30 72 C -14.7444 11.9222 0.0 0
M  V30 73 C -16.1267 11.4039 0.0 0
M  V30 74 C -17.509 12.2678 0.0 0
M  V30 75 C -18.8913 11.7494 0.0 0
M  V30 76 Si -4.6076 25.342 0.0 0
M  V30 77 O -3.7437 26.5515 0.0 0
M  V30 78 O -5.8171 24.4781 0.0 0
M  V30 79 O -3.5133 24.766 0.0 0
M  V30 80 C -6.0475 26.2635 0.0 0
M  V30 81 C -4.9532 27.761 0.0 0
M  V30 82 C -4.9532 23.6141 0.0 0
M  V30 83 C -2.419 25.6876 0.0 0
M  V30 84 C -7.4874 25.6876 0.0 0
M  V30 85 C -8.9273 26.6091 0.0 0
M  V30 86 C -10.3671 26.0331 0.0 0
M  V30 87 C -11.807 26.9547 0.0 0
M  V30 88 C -13.2469 26.3787 0.0 0
M  V30 89 C -14.6868 27.3002 0.0 0
M  V30 90 C -16.1267 26.7243 0.0 0
M  V30 91 Si -7.3722 41.4687 0.0 0
M  V30 92 O -6.5082 42.6782 0.0 0
M  V30 93 O -8.5817 40.6048 0.0 0
M  V30 94 O -6.2779 40.8928 0.0 0
M  V30 95 C -8.8121 42.3903 0.0 0
M  V30 96 C -7.7178 43.8877 0.0 0
M  V30 97 C -7.7178 39.7409 0.0 0
M  V30 98 C -5.1835 41.8143 0.0 0
M  V30 99 C -10.252 41.8143 0.0 0
M  V30 100 C -11.6918 42.7358 0.0 0
M  V30 101 C -13.1317 42.1599 0.0 0
M  V30 102 C -14.5716 43.0814 0.0 0
M  V30 103 C -16.0115 42.5055 0.0 0
M  V30 104 Si -5.5291 49.7625 0.0 0
M  V30 105 O -6.7386 48.8986 0.0 0
M  V30 106 O -4.4348 49.1865 0.0 0
M  V30 107 O -4.6652 50.972 0.0 0
M  V30 108 C -6.969 50.684 0.0 0
M  V30 109 C -5.8747 48.0346 0.0 0
M  V30 110 C -3.3405 50.1081 0.0 0
M  V30 111 C -5.8747 52.1815 0.0 0
M  V30 112 C -8.4089 50.1081 0.0 0
M  V30 113 C -4.55 48.2074 0.0 0
M  V30 114 C -2.2462 49.5321 0.0 0
M  V30 115 C -5.0108 53.391 0.0 0
M  V30 116 Si -11.9798 50.2233 0.0 0
M  V30 117 O -11.1159 51.4328 0.0 0
M  V30 118 O -13.1893 49.3593 0.0 0
M  V30 119 O -10.8855 49.6473 0.0 0
M  V30 120 C -13.4197 51.1448 0.0 0
M  V30 121 C -12.3254 52.6423 0.0 0
M  V30 122 C -12.3254 48.4954 0.0 0
M  V30 123 C -9.7912 50.5688 0.0 0
M  V30 124 C -14.8596 50.5688 0.0 0
M  V30 125 Si -5.9899 58.517 0.0 0
M  V30 126 O -7.1994 57.6531 0.0 0
M  V30 127 O -4.8956 57.9411 0.0 0
M  V30 128 O -5.126 59.7265 0.0 0
M  V30 129 C -7.4298 59.4385 0.0 0
M  V30 130 C -6.3355 56.7892 0.0 0
M  V30 131 C -3.8013 58.8626 0.0 0
M  V30 132 C -6.3355 60.936 0.0 0
M  V30 133 C -5.0108 56.9619 0.0 0
M  V30 134 C -2.7069 58.2866 0.0 0
M  V30 135 C -5.4715 62.1455 0.0 0
M  V30 136 Si -12.4406 58.9778 0.0 0
M  V30 137 O -11.5767 60.1873 0.0 0
M  V30 138 O -13.6501 58.1138 0.0 0
M  V30 139 O -11.3463 58.4018 0.0 0
M  V30 140 C -13.8805 59.8993 0.0 0
M  V30 141 C -12.7862 61.3968 0.0 0
M  V30 142 C -12.7862 57.2499 0.0 0
M  V30 143 C -10.252 59.3234 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 23 24
M  V30 23 1 23 25
M  V30 24 1 23 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 25 29
M  V30 28 1 26 30
M  V30 29 1 27 31
M  V30 30 1 28 32
M  V30 31 1 29 33
M  V30 32 1 30 34
M  V30 33 1 31 35
M  V30 34 1 35 36
M  V30 35 1 36 37
M  V30 36 1 37 38
M  V30 37 1 38 39
M  V30 38 1 39 40
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 41 44
M  V30 42 1 41 45
M  V30 43 1 42 46
M  V30 44 1 43 47
M  V30 45 1 44 48
M  V30 46 1 45 49
M  V30 47 1 46 50
M  V30 48 1 47 51
M  V30 49 1 48 52
M  V30 50 1 49 53
M  V30 51 1 53 54
M  V30 52 1 54 55
M  V30 53 1 55 56
M  V30 54 1 57 58
M  V30 55 1 57 59
M  V30 56 1 57 60
M  V30 57 1 57 61
M  V30 58 1 58 62
M  V30 59 1 59 63
M  V30 60 1 60 64
M  V30 61 1 61 65
M  V30 62 1 65 66
M  V30 63 1 66 67
M  V30 64 1 67 68
M  V30 65 1 68 69
M  V30 66 1 69 70
M  V30 67 1 70 71
M  V30 68 1 71 72
M  V30 69 1 72 73
M  V30 70 1 73 74
M  V30 71 1 74 75
M  V30 72 1 76 77
M  V30 73 1 76 78
M  V30 74 1 76 79
M  V30 75 1 76 80
M  V30 76 1 77 81
M  V30 77 1 78 82
M  V30 78 1 79 83
M  V30 79 1 80 84
M  V30 80 1 84 85
M  V30 81 1 85 86
M  V30 82 1 86 87
M  V30 83 1 87 88
M  V30 84 1 88 89
M  V30 85 1 89 90
M  V30 86 1 91 92
M  V30 87 1 91 93
M  V30 88 1 91 94
M  V30 89 1 91 95
M  V30 90 1 92 96
M  V30 91 1 93 97
M  V30 92 1 94 98
M  V30 93 1 95 99
M  V30 94 1 99 100
M  V30 95 1 100 101
M  V30 96 1 101 102
M  V30 97 1 102 103
M  V30 98 1 104 105
M  V30 99 1 104 106
M  V30 100 1 104 107
M  V30 101 1 104 108
M  V30 102 1 105 109
M  V30 103 1 106 110
M  V30 104 1 107 111
M  V30 105 1 108 112
M  V30 106 1 109 113
M  V30 107 1 110 114
M  V30 108 1 111 115
M  V30 109 1 116 117
M  V30 110 1 116 118
M  V30 111 1 116 119
M  V30 112 1 116 120
M  V30 113 1 117 121
M  V30 114 1 118 122
M  V30 115 1 119 123
M  V30 116 1 120 124
M  V30 117 1 125 126
M  V30 118 1 125 127
M  V30 119 1 125 128
M  V30 120 1 125 129
M  V30 121 1 126 130
M  V30 122 1 127 131
M  V30 123 1 128 132
M  V30 124 1 130 133
M  V30 125 1 131 134
M  V30 126 1 132 135
M  V30 127 1 136 137
M  V30 128 1 136 138
M  V30 129 1 136 139
M  V30 130 1 136 140
M  V30 131 1 137 141
M  V30 132 1 138 142
M  V30 133 1 139 143
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000729A1-20220106-C00004

>  <Row No>
515

$$$$
US20220000729A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 7 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.6499 0.0405 0.0 0
M  V30 3 O -1.731 0.0405 0.0 0
M  V30 4 C -0.0405 1.731 0.0 0
M  V30 5 C -0.0405 -1.6499 0.0 0
M  V30 6 C 3.2998 0.0811 0.0 0
M  V30 7 C -3.4621 0.0811 0.0 0
M  V30 8 C -0.0811 2.0827 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000729A1-20220106-C00005

>  <Row No>
516

$$$$
US20220000729A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 7 6 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.6935 0.0416 0.0 0
M  V30 3 C -0.0416 1.7768 0.0 0
M  V30 4 C -1.7768 0.0416 0.0 0
M  V30 5 C -0.0416 -1.6935 0.0 0
M  V30 6 C 3.387 0.0832 0.0 0
M  V30 7 C -0.0832 2.1377 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000729A1-20220106-C00006

>  <Row No>
517

$$$$
US20220000729A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 63 57 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.1196 -0.9952 0.0 0
M  V30 3 O 1.244 -0.6842 0.0 0
M  V30 4 O 0.9952 1.1196 0.0 0
M  V30 5 C -1.3269 0.8086 0.0 0
M  V30 6 C -0.4354 -2.2392 0.0 0
M  V30 7 C 2.488 0.1244 0.0 0
M  V30 8 C -0.1244 2.2392 0.0 0
M  V30 9 C -2.6746 0.1244 0.0 0
M  V30 10 C 0.9122 -1.7831 0.0 0
M  V30 11 C 3.732 -0.5598 0.0 0
M  V30 12 C -1.5965 1.9075 0.0 0
M  V30 13 N -4.0223 0.933 0.0 0
M  V30 14 Si 1.6587 21.2314 0.0 0
M  V30 15 O 0.539 20.2362 0.0 0
M  V30 16 O 2.9027 20.5472 0.0 0
M  V30 17 O 2.6539 22.351 0.0 0
M  V30 18 C 0.311 22.04 0.0 0
M  V30 19 C 1.2232 18.9921 0.0 0
M  V30 20 C 4.1467 21.3558 0.0 0
M  V30 21 C 1.5343 23.4706 0.0 0
M  V30 22 C -1.0159 21.3558 0.0 0
M  V30 23 C 2.5709 19.4483 0.0 0
M  V30 24 C 5.3907 20.6716 0.0 0
M  V30 25 C 0.0622 23.1389 0.0 0
M  V30 26 C -2.3636 22.1644 0.0 0
M  V30 27 N -3.7113 21.4802 0.0 0
M  V30 28 Si 9.9522 0.4976 0.0 0
M  V30 29 O 8.8326 -0.4976 0.0 0
M  V30 30 O 11.1962 -0.1866 0.0 0
M  V30 31 O 10.9474 1.6172 0.0 0
M  V30 32 C 8.6045 1.3062 0.0 0
M  V30 33 C 9.5168 -1.7416 0.0 0
M  V30 34 C 12.4402 0.622 0.0 0
M  V30 35 C 9.8278 2.7368 0.0 0
M  V30 36 C 7.2568 0.622 0.0 0
M  V30 37 N 5.9091 1.4306 0.0 0
M  V30 38 Si 1.8245 10.7815 0.0 0
M  V30 39 O 0.7049 9.7863 0.0 0
M  V30 40 O 3.0686 10.0973 0.0 0
M  V30 41 O 2.8198 11.9012 0.0 0
M  V30 42 C 0.4768 11.5902 0.0 0
M  V30 43 C 1.3891 8.5423 0.0 0
M  V30 44 C 4.3126 10.9059 0.0 0
M  V30 45 C 1.7001 13.0208 0.0 0
M  V30 46 C -0.85 10.9059 0.0 0
M  V30 47 C -2.1977 11.7146 0.0 0
M  V30 48 N -3.5247 11.0303 0.0 0
M  V30 49 Si 0.6634 -8.957 0.0 0
M  V30 50 O 1.9075 -9.6412 0.0 0
M  V30 51 O 1.6587 -7.8373 0.0 0
M  V30 52 O -0.4561 -9.9522 0.0 0
M  V30 53 C -0.6634 -8.1483 0.0 0
M  V30 54 C -2.0111 -8.8326 0.0 0
M  V30 55 N -3.3588 -8.0239 0.0 0
M  V30 56 Si 11.6109 10.7815 0.0 0
M  V30 57 O 12.8549 10.0973 0.0 0
M  V30 58 O 12.6061 11.9012 0.0 0
M  V30 59 O 10.4913 9.7863 0.0 0
M  V30 60 C 10.2632 11.5902 0.0 0
M  V30 61 C 8.9155 10.9059 0.0 0
M  V30 62 C 7.5885 11.7146 0.0 0
M  V30 63 N 6.2408 11.0303 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 14 15
M  V30 14 1 14 16
M  V30 15 1 14 17
M  V30 16 1 14 18
M  V30 17 1 15 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 26 27
M  V30 26 1 28 29
M  V30 27 1 28 30
M  V30 28 1 28 31
M  V30 29 1 28 32
M  V30 30 1 29 33
M  V30 31 1 30 34
M  V30 32 1 31 35
M  V30 33 1 32 36
M  V30 34 1 36 37
M  V30 35 1 38 39
M  V30 36 1 38 40
M  V30 37 1 38 41
M  V30 38 1 38 42
M  V30 39 1 39 43
M  V30 40 1 40 44
M  V30 41 1 41 45
M  V30 42 1 42 46
M  V30 43 1 46 47
M  V30 44 1 47 48
M  V30 45 1 49 50
M  V30 46 1 49 51
M  V30 47 1 49 52
M  V30 48 1 49 53
M  V30 49 1 53 54
M  V30 50 1 54 55
M  V30 51 1 56 57
M  V30 52 1 56 58
M  V30 53 1 56 59
M  V30 54 1 56 60
M  V30 55 1 60 61
M  V30 56 1 61 62
M  V30 57 1 62 63
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000729A1-20220106-C00007

>  <Row No>
518

$$$$
US20220000729A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 75 69 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.1178 -0.9654 0.0 0
M  V30 3 O 1.2194 -0.6605 0.0 0
M  V30 4 O 0.9654 1.1178 0.0 0
M  V30 5 C -1.3718 0.8129 0.0 0
M  V30 6 C -0.4572 -2.1848 0.0 0
M  V30 7 C 2.4389 0.1524 0.0 0
M  V30 8 C -0.1524 2.2356 0.0 0
M  V30 9 C -2.7437 0.1524 0.0 0
M  V30 10 C 0.8891 -1.7275 0.0 0
M  V30 11 C 3.6583 -0.5081 0.0 0
M  V30 12 C -1.6513 1.9308 0.0 0
M  V30 13 N -4.1156 0.9654 0.0 0
M  V30 14 C -5.4875 0.3048 0.0 0
M  V30 15 C -4.1918 2.5151 0.0 0
M  V30 16 Si 0.2032 26.015 0.0 0
M  V30 17 O -0.9145 25.0496 0.0 0
M  V30 18 O 1.4226 25.3544 0.0 0
M  V30 19 O 1.1686 27.1328 0.0 0
M  V30 20 C -1.1686 26.828 0.0 0
M  V30 21 C -0.254 23.8301 0.0 0
M  V30 22 C 2.6421 26.1674 0.0 0
M  V30 23 C 0.0508 28.2506 0.0 0
M  V30 24 C -2.5405 26.1674 0.0 0
M  V30 25 C 1.0924 24.2874 0.0 0
M  V30 26 C 3.8616 25.5069 0.0 0
M  V30 27 C -1.4481 27.9458 0.0 0
M  V30 28 C -3.9124 26.9804 0.0 0
M  V30 29 N -5.2843 26.3198 0.0 0
M  V30 30 C -6.6561 27.1328 0.0 0
M  V30 31 C -5.3605 24.9226 0.0 0
M  V30 32 Si 0.2032 -8.1296 0.0 0
M  V30 33 O -0.9145 -9.095 0.0 0
M  V30 34 O 1.4226 -8.7902 0.0 0
M  V30 35 O 1.1686 -7.0118 0.0 0
M  V30 36 C -1.1686 -7.3167 0.0 0
M  V30 37 C -0.254 -10.3145 0.0 0
M  V30 38 C 2.6421 -7.9772 0.0 0
M  V30 39 C 0.0508 -5.894 0.0 0
M  V30 40 C -2.5405 -7.9772 0.0 0
M  V30 41 N -3.9124 -7.1642 0.0 0
M  V30 42 C -5.2843 -7.8248 0.0 0
M  V30 43 C -3.9886 -5.6145 0.0 0
M  V30 44 Si 1.0162 16.0561 0.0 0
M  V30 45 O -0.1016 15.0907 0.0 0
M  V30 46 O 2.2356 15.3956 0.0 0
M  V30 47 O 1.9816 17.1739 0.0 0
M  V30 48 C -0.3556 16.8691 0.0 0
M  V30 49 C 0.5589 13.8712 0.0 0
M  V30 50 C 3.4551 16.2085 0.0 0
M  V30 51 C 0.8637 18.2918 0.0 0
M  V30 52 C -1.7275 16.2085 0.0 0
M  V30 53 C -3.0994 17.0215 0.0 0
M  V30 54 N -4.4713 16.361 0.0 0
M  V30 55 C -5.8432 17.1739 0.0 0
M  V30 56 C -4.5475 14.9637 0.0 0
M  V30 57 Si -0.2032 -15.8529 0.0 0
M  V30 58 O 1.0162 -16.5134 0.0 0
M  V30 59 O 0.7621 -14.735 0.0 0
M  V30 60 O -1.321 -16.8183 0.0 0
M  V30 61 C -1.5751 -15.0399 0.0 0
M  V30 62 C -2.947 -15.7004 0.0 0
M  V30 63 N -4.3189 -14.8875 0.0 0
M  V30 64 C -5.6907 -15.548 0.0 0
M  V30 65 C -4.3951 -13.3377 0.0 0
M  V30 66 Si 0.8129 8.7394 0.0 0
M  V30 67 O 2.0324 8.0788 0.0 0
M  V30 68 O 1.7783 9.8572 0.0 0
M  V30 69 O -0.3048 7.774 0.0 0
M  V30 70 C -0.5589 9.5523 0.0 0
M  V30 71 C -1.9308 8.8918 0.0 0
M  V30 72 C -3.3026 9.7048 0.0 0
M  V30 73 N -4.6745 9.0442 0.0 0
M  V30 74 C -6.0464 9.8572 0.0 0
M  V30 75 C -4.7507 7.6469 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 15 1 16 17
M  V30 16 1 16 18
M  V30 17 1 16 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 28 29
M  V30 28 1 29 30
M  V30 29 1 29 31
M  V30 30 1 32 33
M  V30 31 1 32 34
M  V30 32 1 32 35
M  V30 33 1 32 36
M  V30 34 1 33 37
M  V30 35 1 34 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 1 40 41
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 44 45
M  V30 42 1 44 46
M  V30 43 1 44 47
M  V30 44 1 44 48
M  V30 45 1 45 49
M  V30 46 1 46 50
M  V30 47 1 47 51
M  V30 48 1 48 52
M  V30 49 1 52 53
M  V30 50 1 53 54
M  V30 51 1 54 55
M  V30 52 1 54 56
M  V30 53 1 57 58
M  V30 54 1 57 59
M  V30 55 1 57 60
M  V30 56 1 57 61
M  V30 57 1 61 62
M  V30 58 1 62 63
M  V30 59 1 63 64
M  V30 60 1 63 65
M  V30 61 1 66 67
M  V30 62 1 66 68
M  V30 63 1 66 69
M  V30 64 1 66 70
M  V30 65 1 70 71
M  V30 66 1 71 72
M  V30 67 1 72 73
M  V30 68 1 73 74
M  V30 69 1 73 75
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027002.cdx

>  <name>
US20220000729A1-20220106-C00008

>  <Row No>
519

$$$$
US20220000729A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 152 146 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.4598 -0.6122 0.0 0
M  V30 3 O 0.6122 -1.1773 0.0 0
M  V30 4 O -0.8947 1.4598 0.0 0
M  V30 5 C 1.1773 0.8947 0.0 0
M  V30 6 C -2.9197 0.2825 0.0 0
M  V30 7 C 1.9779 -1.036 0.0 0
M  V30 8 C -0.6593 3.061 0.0 0
M  V30 9 C 2.3546 0.2825 0.0 0
M  V30 10 C -4.3796 -0.3296 0.0 0
M  V30 11 C 2.5901 -2.2133 0.0 0
M  V30 12 C 0.7063 3.2023 0.0 0
M  V30 13 C 3.5319 1.1773 0.0 0
M  V30 14 N 4.7093 0.5651 0.0 0
M  V30 15 C 4.568 -0.8005 0.0 0
M  V30 16 C 5.8866 1.4598 0.0 0
M  V30 17 C 5.7453 -1.4127 0.0 0
M  V30 18 C 7.0639 0.8476 0.0 0
M  V30 19 O 5.604 -2.7784 0.0 0
M  V30 20 C 8.2413 1.7424 0.0 0
M  V30 21 Si 9.4186 1.1302 0.0 0
M  V30 22 O 10.3134 2.3546 0.0 0
M  V30 23 O 8.1942 0.1883 0.0 0
M  V30 24 O 10.5959 0.518 0.0 0
M  V30 25 C 9.136 3.5319 0.0 0
M  V30 26 C 8.0529 -1.1773 0.0 0
M  V30 27 C 11.9616 0.6593 0.0 0
M  V30 28 C 10.0308 4.7564 0.0 0
M  V30 29 C 9.3715 -1.4127 0.0 0
M  V30 30 C 12.9035 1.8837 0.0 0
M  V30 31 Si -1.1302 19.5907 0.0 0
M  V30 32 O -2.5901 18.9785 0.0 0
M  V30 33 O -0.518 18.4134 0.0 0
M  V30 34 O -2.025 21.0506 0.0 0
M  V30 35 C 0.047 20.4855 0.0 0
M  V30 36 C -4.05 19.8733 0.0 0
M  V30 37 C 0.8476 18.5547 0.0 0
M  V30 38 C -1.7895 22.6518 0.0 0
M  V30 39 C 1.2244 19.8733 0.0 0
M  V30 40 C -5.5099 19.2611 0.0 0
M  V30 41 C 1.4598 17.3773 0.0 0
M  V30 42 C -0.4238 22.7931 0.0 0
M  V30 43 C 2.4017 20.7681 0.0 0
M  V30 44 N 3.579 20.1558 0.0 0
M  V30 45 C 4.7564 21.0506 0.0 0
M  V30 46 C 3.4378 18.7901 0.0 0
M  V30 47 C 5.9337 20.4384 0.0 0
M  V30 48 C 7.111 21.3332 0.0 0
M  V30 49 Si 8.2884 20.721 0.0 0
M  V30 50 O 9.1831 21.9454 0.0 0
M  V30 51 O 7.0639 19.8262 0.0 0
M  V30 52 O 9.4657 20.1087 0.0 0
M  V30 53 C 8.0058 23.1698 0.0 0
M  V30 54 C 6.9227 18.4605 0.0 0
M  V30 55 C 10.8314 20.25 0.0 0
M  V30 56 C 8.9006 24.3471 0.0 0
M  V30 57 C 8.2413 18.225 0.0 0
M  V30 58 C 11.7733 21.4745 0.0 0
M  V30 59 Si -1.1302 37.6745 0.0 0
M  V30 60 O -2.5901 37.0623 0.0 0
M  V30 61 O -2.025 39.1344 0.0 0
M  V30 62 O -0.518 36.4972 0.0 0
M  V30 63 C 0.047 38.5693 0.0 0
M  V30 64 C -4.05 37.9571 0.0 0
M  V30 65 C -1.7895 40.7356 0.0 0
M  V30 66 C 0.8476 36.6385 0.0 0
M  V30 67 C 1.2244 37.9571 0.0 0
M  V30 68 C -5.5099 37.3449 0.0 0
M  V30 69 C -0.4238 40.8769 0.0 0
M  V30 70 C 1.4598 35.4611 0.0 0
M  V30 71 C 2.4017 38.8518 0.0 0
M  V30 72 N 3.579 38.2396 0.0 0
M  V30 73 C 4.7564 39.1344 0.0 0
M  V30 74 C 5.9337 38.5222 0.0 0
M  V30 75 C 7.111 39.417 0.0 0
M  V30 76 Si 8.2884 38.8048 0.0 0
M  V30 77 O 7.0639 37.8629 0.0 0
M  V30 78 O 9.4657 38.1925 0.0 0
M  V30 79 O 9.1831 39.9821 0.0 0
M  V30 80 C 6.9227 36.4972 0.0 0
M  V30 81 C 10.8314 38.3338 0.0 0
M  V30 82 C 8.0058 41.2065 0.0 0
M  V30 83 C 8.2413 36.2617 0.0 0
M  V30 84 C 11.7733 39.5111 0.0 0
M  V30 85 C 8.9006 42.4309 0.0 0
M  V30 86 Si 7.9116 10.9256 0.0 0
M  V30 87 O 6.6872 9.9837 0.0 0
M  V30 88 O 9.0889 10.3134 0.0 0
M  V30 89 O 8.8535 12.1029 0.0 0
M  V30 90 C 6.4517 11.8203 0.0 0
M  V30 91 C 6.5459 8.618 0.0 0
M  V30 92 C 10.4546 10.4546 0.0 0
M  V30 93 C 7.629 13.3273 0.0 0
M  V30 94 C 4.9918 11.2081 0.0 0
M  V30 95 C 3.5319 12.1029 0.0 0
M  V30 96 N 2.0721 11.4907 0.0 0
M  V30 97 C 1.9308 10.125 0.0 0
M  V30 98 C 0.6122 12.3855 0.0 0
M  V30 99 C 3.2494 9.8895 0.0 0
M  V30 100 C -0.8476 11.7733 0.0 0
M  V30 101 O 3.1081 8.5238 0.0 0
M  V30 102 C -2.3075 12.668 0.0 0
M  V30 103 Si -3.7674 12.0558 0.0 0
M  V30 104 O -5.2273 11.4436 0.0 0
M  V30 105 O -4.6622 13.5157 0.0 0
M  V30 106 O -3.1552 10.8785 0.0 0
M  V30 107 C -6.6872 12.3384 0.0 0
M  V30 108 C -4.4267 15.1169 0.0 0
M  V30 109 C -1.7895 11.0198 0.0 0
M  V30 110 Si 8.2884 28.6326 0.0 0
M  V30 111 O 7.0639 27.7378 0.0 0
M  V30 112 O 9.4657 28.0204 0.0 0
M  V30 113 O 9.2302 29.857 0.0 0
M  V30 114 C 6.8285 29.5274 0.0 0
M  V30 115 C 6.9227 26.3721 0.0 0
M  V30 116 C 10.8314 28.1617 0.0 0
M  V30 117 C 8.0058 31.0815 0.0 0
M  V30 118 C 5.3686 28.9152 0.0 0
M  V30 119 C 3.9087 29.8099 0.0 0
M  V30 120 N 2.4488 29.1977 0.0 0
M  V30 121 C 0.9889 30.0925 0.0 0
M  V30 122 C 2.3075 27.832 0.0 0
M  V30 123 C -0.4709 29.4803 0.0 0
M  V30 124 C -1.9308 30.3751 0.0 0
M  V30 125 Si -3.3907 29.7629 0.0 0
M  V30 126 O -4.8506 29.1506 0.0 0
M  V30 127 O -4.2854 31.2227 0.0 0
M  V30 128 O -2.7784 28.5855 0.0 0
M  V30 129 C -6.3104 30.0454 0.0 0
M  V30 130 C -4.05 32.8239 0.0 0
M  V30 131 C -1.4127 28.7268 0.0 0
M  V30 132 Si 8.6651 48.2234 0.0 0
M  V30 133 O 7.4878 47.3286 0.0 0
M  V30 134 O 9.8424 47.6112 0.0 0
M  V30 135 O 9.607 49.4478 0.0 0
M  V30 136 C 7.2052 49.1182 0.0 0
M  V30 137 C 7.3465 45.9629 0.0 0
M  V30 138 C 11.2081 47.7525 0.0 0
M  V30 139 C 8.3825 50.6722 0.0 0
M  V30 140 C 5.7453 48.506 0.0 0
M  V30 141 C 4.2854 49.4007 0.0 0
M  V30 142 N 2.8255 48.7885 0.0 0
M  V30 143 C 1.3657 49.6833 0.0 0
M  V30 144 C -0.0941 49.0711 0.0 0
M  V30 145 C -1.554 49.9658 0.0 0
M  V30 146 Si -3.0139 49.3536 0.0 0
M  V30 147 O -4.4738 48.7414 0.0 0
M  V30 148 O -3.9087 50.8135 0.0 0
M  V30 149 O -2.4017 48.1763 0.0 0
M  V30 150 C -5.9337 49.6362 0.0 0
M  V30 151 C -3.6732 52.4147 0.0 0
M  V30 152 C -1.036 48.3176 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 47 48
M  V30 47 1 48 49
M  V30 48 1 49 50
M  V30 49 1 49 51
M  V30 50 1 49 52
M  V30 51 1 50 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 59 60
M  V30 58 1 59 61
M  V30 59 1 59 62
M  V30 60 1 59 63
M  V30 61 1 60 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 71 72
M  V30 70 1 72 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 75 76
M  V30 74 1 76 77
M  V30 75 1 76 78
M  V30 76 1 76 79
M  V30 77 1 77 80
M  V30 78 1 78 81
M  V30 79 1 79 82
M  V30 80 1 80 83
M  V30 81 1 81 84
M  V30 82 1 82 85
M  V30 83 1 86 87
M  V30 84 1 86 88
M  V30 85 1 86 89
M  V30 86 1 86 90
M  V30 87 1 87 91
M  V30 88 1 88 92
M  V30 89 1 89 93
M  V30 90 1 90 94
M  V30 91 1 94 95
M  V30 92 1 95 96
M  V30 93 1 96 97
M  V30 94 1 96 98
M  V30 95 1 97 99
M  V30 96 1 98 100
M  V30 97 1 99 101
M  V30 98 1 100 102
M  V30 99 1 102 103
M  V30 100 1 103 104
M  V30 101 1 103 105
M  V30 102 1 103 106
M  V30 103 1 104 107
M  V30 104 1 105 108
M  V30 105 1 106 109
M  V30 106 1 110 111
M  V30 107 1 110 112
M  V30 108 1 110 113
M  V30 109 1 110 114
M  V30 110 1 111 115
M  V30 111 1 112 116
M  V30 112 1 113 117
M  V30 113 1 114 118
M  V30 114 1 118 119
M  V30 115 1 119 120
M  V30 116 1 120 121
M  V30 117 1 120 122
M  V30 118 1 121 123
M  V30 119 1 123 124
M  V30 120 1 124 125
M  V30 121 1 125 126
M  V30 122 1 125 127
M  V30 123 1 125 128
M  V30 124 1 126 129
M  V30 125 1 127 130
M  V30 126 1 128 131
M  V30 127 1 132 133
M  V30 128 1 132 134
M  V30 129 1 132 135
M  V30 130 1 132 136
M  V30 131 1 133 137
M  V30 132 1 134 138
M  V30 133 1 135 139
M  V30 134 1 136 140
M  V30 135 1 140 141
M  V30 136 1 141 142
M  V30 137 1 142 143
M  V30 138 1 143 144
M  V30 139 1 144 145
M  V30 140 1 145 146
M  V30 141 1 146 147
M  V30 142 1 146 148
M  V30 143 1 146 149
M  V30 144 1 147 150
M  V30 145 1 148 151
M  V30 146 1 149 152
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000729A1-20220106-C00009

>  <Row No>
520

$$$$
US20220000729A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 179 173 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.2274 -0.9072 0.0 0
M  V30 3 O 1.1206 -0.587 0.0 0
M  V30 4 O 0.9072 1.2274 0.0 0
M  V30 5 C -1.4408 0.9072 0.0 0
M  V30 6 C -1.3875 -2.2413 0.0 0
M  V30 7 C 2.4548 -0.4269 0.0 0
M  V30 8 C -0.3201 2.4548 0.0 0
M  V30 9 C -2.8817 0.3201 0.0 0
M  V30 10 C -0.1067 -2.4548 0.0 0
M  V30 11 C 3.362 0.8004 0.0 0
M  V30 12 C 0.587 3.6822 0.0 0
M  V30 13 C -4.3226 1.2274 0.0 0
M  V30 14 N -5.7635 0.6403 0.0 0
M  V30 15 C -5.9236 -0.6937 0.0 0
M  V30 16 C -7.2043 1.5476 0.0 0
M  V30 17 C -4.8029 -1.2807 0.0 0
M  V30 18 C -8.6452 0.9605 0.0 0
M  V30 19 C -4.963 -2.6149 0.0 0
M  V30 20 C -10.0861 1.8678 0.0 0
M  V30 21 Si -11.527 1.2807 0.0 0
M  V30 22 O -12.4342 2.7216 0.0 0
M  V30 23 O -10.9399 0.16 0.0 0
M  V30 24 O -12.9678 0.6937 0.0 0
M  V30 25 C -12.2207 4.3226 0.0 0
M  V30 26 C -9.6058 0.3201 0.0 0
M  V30 27 C -14.4087 1.6009 0.0 0
M  V30 28 C -10.8866 4.4827 0.0 0
M  V30 29 C -9.0188 -0.8004 0.0 0
M  V30 30 C -15.8496 1.0139 0.0 0
M  V30 31 Si -2.1346 20.4924 0.0 0
M  V30 32 O -3.362 19.5852 0.0 0
M  V30 33 O -1.0139 19.9054 0.0 0
M  V30 34 O -1.2274 21.7198 0.0 0
M  V30 35 C -3.5755 21.3996 0.0 0
M  V30 36 C -3.5221 18.251 0.0 0
M  V30 37 C 0.3201 20.0655 0.0 0
M  V30 38 C -2.4548 22.9472 0.0 0
M  V30 39 C -5.0163 20.8126 0.0 0
M  V30 40 C -2.2413 18.0376 0.0 0
M  V30 41 C 1.2274 21.2929 0.0 0
M  V30 42 C -1.5476 24.1746 0.0 0
M  V30 43 C -6.4572 21.7198 0.0 0
M  V30 44 N -7.8981 21.1328 0.0 0
M  V30 45 C -8.0582 19.7987 0.0 0
M  V30 46 C -9.339 22.04 0.0 0
M  V30 47 C -6.9375 19.2116 0.0 0
M  V30 48 C -10.7798 21.453 0.0 0
M  V30 49 N -7.0976 17.8775 0.0 0
M  V30 50 C -12.2207 22.3602 0.0 0
M  V30 51 Si -13.6616 21.7732 0.0 0
M  V30 52 O -14.5688 23.2141 0.0 0
M  V30 53 O -13.0746 20.6525 0.0 0
M  V30 54 O -15.1025 21.1862 0.0 0
M  V30 55 C -14.3553 24.815 0.0 0
M  V30 56 C -11.7404 20.8126 0.0 0
M  V30 57 C -16.5433 22.0934 0.0 0
M  V30 58 C -13.0212 24.9751 0.0 0
M  V30 59 C -11.1534 19.6919 0.0 0
M  V30 60 C -17.9842 21.5064 0.0 0
M  V30 61 Si -11.527 42.2656 0.0 0
M  V30 62 O -12.9678 41.6786 0.0 0
M  V30 63 O -12.4342 43.7065 0.0 0
M  V30 64 O -10.9399 41.145 0.0 0
M  V30 65 C -10.4063 43.1729 0.0 0
M  V30 66 C -14.4087 42.5858 0.0 0
M  V30 67 C -12.2207 45.3075 0.0 0
M  V30 68 C -12.1673 40.2377 0.0 0
M  V30 69 C -9.2856 42.5858 0.0 0
M  V30 70 C -15.8496 41.9988 0.0 0
M  V30 71 C -10.8866 45.4676 0.0 0
M  V30 72 C -11.9539 38.957 0.0 0
M  V30 73 C -8.1649 43.4931 0.0 0
M  V30 74 N -7.0442 42.906 0.0 0
M  V30 75 C -7.2043 41.5719 0.0 0
M  V30 76 C -5.9236 43.8132 0.0 0
M  V30 77 C -6.0836 40.9849 0.0 0
M  V30 78 C -4.8029 43.2262 0.0 0
M  V30 79 C -6.2437 39.6507 0.0 0
M  V30 80 C -3.6822 44.1334 0.0 0
M  V30 81 Si -7.6846 39.0637 0.0 0
M  V30 82 Si -2.5615 43.5464 0.0 0
M  V30 83 O -9.1255 39.9709 0.0 0
M  V30 84 O -9.1255 38.4767 0.0 0
M  V30 85 O -6.5639 38.4767 0.0 0
M  V30 86 O -3.7889 42.6392 0.0 0
M  V30 87 O -1.4408 42.9594 0.0 0
M  V30 88 O -1.6543 44.7738 0.0 0
M  V30 89 C -9.2856 41.6253 0.0 0
M  V30 90 C -10.5664 39.3839 0.0 0
M  V30 91 C -5.2832 39.0103 0.0 0
M  V30 92 C -3.949 41.3051 0.0 0
M  V30 93 C -0.1067 43.1195 0.0 0
M  V30 94 C -2.8817 46.0012 0.0 0
M  V30 95 C -10.7265 42.5325 0.0 0
M  V30 96 C -11.7938 38.4767 0.0 0
M  V30 97 C -4.3759 38.1031 0.0 0
M  V30 98 C -2.6149 41.4652 0.0 0
M  V30 99 C 0.1067 44.7205 0.0 0
M  V30 100 C -4.4827 45.7878 0.0 0
M  V30 101 Si -2.5615 11.1 0.0 0
M  V30 102 O -3.7889 10.1928 0.0 0
M  V30 103 O -1.4408 10.513 0.0 0
M  V30 104 O -1.6543 12.3274 0.0 0
M  V30 105 C -4.0024 12.0072 0.0 0
M  V30 106 C -3.949 8.8587 0.0 0
M  V30 107 C -0.1067 10.6731 0.0 0
M  V30 108 C -2.8817 13.5549 0.0 0
M  V30 109 C -5.4433 11.4202 0.0 0
M  V30 110 C -6.8841 12.3274 0.0 0
M  V30 111 N -8.325 11.7404 0.0 0
M  V30 112 C -8.4851 10.4063 0.0 0
M  V30 113 C -9.7659 12.6476 0.0 0
M  V30 114 C -7.2043 10.1928 0.0 0
M  V30 115 C -11.2068 12.0606 0.0 0
M  V30 116 C -7.3644 8.8587 0.0 0
M  V30 117 C -12.6476 12.9678 0.0 0
M  V30 118 Si -14.0885 12.3808 0.0 0
M  V30 119 O -15.5294 11.7938 0.0 0
M  V30 120 O -14.9957 13.8217 0.0 0
M  V30 121 O -13.5015 11.2601 0.0 0
M  V30 122 C -16.9703 12.701 0.0 0
M  V30 123 C -14.7823 15.4227 0.0 0
M  V30 124 C -12.1673 11.4202 0.0 0
M  V30 125 Si -2.5615 29.8848 0.0 0
M  V30 126 O -3.7889 28.9776 0.0 0
M  V30 127 O -1.4408 29.2978 0.0 0
M  V30 128 O -1.6543 31.1122 0.0 0
M  V30 129 C -4.0024 30.792 0.0 0
M  V30 130 C -3.949 27.6434 0.0 0
M  V30 131 C -0.1067 29.4579 0.0 0
M  V30 132 C -2.8817 32.3396 0.0 0
M  V30 133 C -5.4433 30.205 0.0 0
M  V30 134 C -6.8841 31.1122 0.0 0
M  V30 135 N -8.325 30.5252 0.0 0
M  V30 136 C -8.4851 29.191 0.0 0
M  V30 137 C -9.7659 31.4324 0.0 0
M  V30 138 C -7.2043 28.9776 0.0 0
M  V30 139 C -11.2068 30.8454 0.0 0
M  V30 140 N -7.3644 27.6434 0.0 0
M  V30 141 C -12.6476 31.7526 0.0 0
M  V30 142 Si -14.0885 31.1656 0.0 0
M  V30 143 O -15.5294 30.5785 0.0 0
M  V30 144 O -14.9957 32.6064 0.0 0
M  V30 145 O -13.5015 30.0449 0.0 0
M  V30 146 C -16.9703 31.4858 0.0 0
M  V30 147 C -14.7823 34.2074 0.0 0
M  V30 148 C -12.1673 30.205 0.0 0
M  V30 149 Si -2.5615 54.6465 0.0 0
M  V30 150 O -3.7889 53.7393 0.0 0
M  V30 151 O -1.4408 54.0595 0.0 0
M  V30 152 O -1.6543 55.8739 0.0 0
M  V30 153 C -4.0024 55.5537 0.0 0
M  V30 154 C -3.949 52.4051 0.0 0
M  V30 155 C -0.1067 54.2196 0.0 0
M  V30 156 C -2.8817 57.1013 0.0 0
M  V30 157 C -5.4433 54.9667 0.0 0
M  V30 158 C -6.8841 55.8739 0.0 0
M  V30 159 N -8.325 55.2869 0.0 0
M  V30 160 C -9.7659 56.1941 0.0 0
M  V30 161 C -8.4851 53.9527 0.0 0
M  V30 162 C -11.2068 55.6071 0.0 0
M  V30 163 C -7.3644 53.3657 0.0 0
M  V30 164 C -12.6476 56.5143 0.0 0
M  V30 165 C -7.5245 52.0316 0.0 0
M  V30 166 Si -14.0885 55.9273 0.0 0
M  V30 167 Si -8.9654 51.4446 0.0 0
M  V30 168 O -15.5294 55.3403 0.0 0
M  V30 169 O -14.9957 57.3682 0.0 0
M  V30 170 O -13.5015 54.8066 0.0 0
M  V30 171 O -10.4063 52.3518 0.0 0
M  V30 172 O -10.4063 50.8575 0.0 0
M  V30 173 O -7.8447 50.8575 0.0 0
M  V30 174 C -16.9703 56.2475 0.0 0
M  V30 175 C -14.7823 58.9691 0.0 0
M  V30 176 C -12.1673 54.9667 0.0 0
M  V30 177 C -10.5664 54.0061 0.0 0
M  V30 178 C -11.8472 51.7647 0.0 0
M  V30 179 C -6.5639 51.3912 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 46 48
M  V30 47 1 47 49
M  V30 48 1 48 50
M  V30 49 1 50 51
M  V30 50 1 51 52
M  V30 51 1 51 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 56 59
M  V30 58 1 57 60
M  V30 59 1 61 62
M  V30 60 1 61 63
M  V30 61 1 61 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 68 72
M  V30 70 1 69 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 74 76
M  V30 74 1 75 77
M  V30 75 1 76 78
M  V30 76 1 77 79
M  V30 77 1 78 80
M  V30 78 1 79 81
M  V30 79 1 80 82
M  V30 80 1 81 83
M  V30 81 1 81 84
M  V30 82 1 81 85
M  V30 83 1 82 86
M  V30 84 1 82 87
M  V30 85 1 82 88
M  V30 86 1 83 89
M  V30 87 1 84 90
M  V30 88 1 85 91
M  V30 89 1 86 92
M  V30 90 1 87 93
M  V30 91 1 88 94
M  V30 92 1 89 95
M  V30 93 1 90 96
M  V30 94 1 91 97
M  V30 95 1 92 98
M  V30 96 1 93 99
M  V30 97 1 94 100
M  V30 98 1 101 102
M  V30 99 1 101 103
M  V30 100 1 101 104
M  V30 101 1 101 105
M  V30 102 1 102 106
M  V30 103 1 103 107
M  V30 104 1 104 108
M  V30 105 1 105 109
M  V30 106 1 109 110
M  V30 107 1 110 111
M  V30 108 1 111 112
M  V30 109 1 111 113
M  V30 110 1 112 114
M  V30 111 1 113 115
M  V30 112 2 114 116
M  V30 113 1 115 117
M  V30 114 1 117 118
M  V30 115 1 118 119
M  V30 116 1 118 120
M  V30 117 1 118 121
M  V30 118 1 119 122
M  V30 119 1 120 123
M  V30 120 1 121 124
M  V30 121 1 125 126
M  V30 122 1 125 127
M  V30 123 1 125 128
M  V30 124 1 125 129
M  V30 125 1 126 130
M  V30 126 1 127 131
M  V30 127 1 128 132
M  V30 128 1 129 133
M  V30 129 1 133 134
M  V30 130 1 134 135
M  V30 131 1 135 136
M  V30 132 1 135 137
M  V30 133 1 136 138
M  V30 134 1 137 139
M  V30 135 1 138 140
M  V30 136 1 139 141
M  V30 137 1 141 142
M  V30 138 1 142 143
M  V30 139 1 142 144
M  V30 140 1 142 145
M  V30 141 1 143 146
M  V30 142 1 144 147
M  V30 143 1 145 148
M  V30 144 1 149 150
M  V30 145 1 149 151
M  V30 146 1 149 152
M  V30 147 1 149 153
M  V30 148 1 150 154
M  V30 149 1 151 155
M  V30 150 1 152 156
M  V30 151 1 153 157
M  V30 152 1 157 158
M  V30 153 1 158 159
M  V30 154 1 159 160
M  V30 155 1 159 161
M  V30 156 1 160 162
M  V30 157 1 161 163
M  V30 158 1 162 164
M  V30 159 1 163 165
M  V30 160 1 164 166
M  V30 161 1 165 167
M  V30 162 1 166 168
M  V30 163 1 166 169
M  V30 164 1 166 170
M  V30 165 1 167 171
M  V30 166 1 167 172
M  V30 167 1 167 173
M  V30 168 1 168 174
M  V30 169 1 169 175
M  V30 170 1 170 176
M  V30 171 1 171 177
M  V30 172 1 172 178
M  V30 173 1 173 179
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028002.cdx

>  <name>
US20220000729A1-20220106-C00010

>  <Row No>
521

$$$$
US20220000729A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 143 133 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.2095 -0.8639 0.0 0
M  V30 3 O 1.0943 -0.5759 0.0 0
M  V30 4 O 0.8639 1.2095 0.0 0
M  V30 5 C -1.4398 0.9215 0.0 0
M  V30 6 C -0.3455 -1.7278 0.0 0
M  V30 7 C 2.1886 0.3455 0.0 0
M  V30 8 C -0.3455 2.419 0.0 0
M  V30 9 C -2.8797 0.3455 0.0 0
M  V30 10 C 0.8639 -1.1519 0.0 0
M  V30 11 C 3.2829 -0.2303 0.0 0
M  V30 12 C 0.2303 3.8589 0.0 0
M  V30 13 C -4.3196 1.2671 0.0 0
M  V30 14 C -5.7595 0.6911 0.0 0
M  V30 15 C -7.1994 1.6126 0.0 0
M  V30 16 C -8.6393 1.0367 0.0 0
M  V30 17 C -10.0792 1.9582 0.0 0
M  V30 18 C -11.5191 1.3822 0.0 0
M  V30 19 C -12.9589 2.3038 0.0 0
M  V30 20 C -14.3988 1.7278 0.0 0
M  V30 21 C -15.8387 2.6493 0.0 0
M  V30 22 C -17.2786 2.0734 0.0 0
M  V30 23 Si -4.6076 17.509 0.0 0
M  V30 24 O -3.7437 18.7185 0.0 0
M  V30 25 O -3.5133 16.933 0.0 0
M  V30 26 O -5.8171 16.6451 0.0 0
M  V30 27 C -6.0475 18.4305 0.0 0
M  V30 28 C -4.9532 19.928 0.0 0
M  V30 29 C -2.419 17.8546 0.0 0
M  V30 30 C -4.9532 15.7811 0.0 0
M  V30 31 C -7.4874 17.8546 0.0 0
M  V30 32 C -4.0892 21.1375 0.0 0
M  V30 33 C -1.3246 17.2786 0.0 0
M  V30 34 C -3.6861 16.3571 0.0 0
M  V30 35 C -8.9273 18.7761 0.0 0
M  V30 36 C -10.3671 18.2001 0.0 0
M  V30 37 C -11.807 19.1217 0.0 0
M  V30 38 C -13.2469 18.5457 0.0 0
M  V30 39 C -14.6868 19.4672 0.0 0
M  V30 40 C -16.1267 18.8913 0.0 0
M  V30 41 Si -7.3722 32.7142 0.0 0
M  V30 42 O -6.5082 33.9237 0.0 0
M  V30 43 O -6.2779 32.1383 0.0 0
M  V30 44 O -8.5817 31.8503 0.0 0
M  V30 45 C -8.8121 33.6357 0.0 0
M  V30 46 C -7.7178 35.1332 0.0 0
M  V30 47 C -5.1835 33.0598 0.0 0
M  V30 48 C -7.7178 30.9863 0.0 0
M  V30 49 C -10.252 33.0598 0.0 0
M  V30 50 C -6.8538 36.3427 0.0 0
M  V30 51 C -4.0892 32.4838 0.0 0
M  V30 52 C -6.4507 31.5623 0.0 0
M  V30 53 C -11.6918 33.9813 0.0 0
M  V30 54 C -13.1317 33.4054 0.0 0
M  V30 55 C -14.5716 34.3269 0.0 0
M  V30 56 C -16.0115 33.7509 0.0 0
M  V30 57 Si -2.3038 9.676 0.0 0
M  V30 58 O -1.4974 10.8279 0.0 0
M  V30 59 O -3.4557 8.8697 0.0 0
M  V30 60 O -1.2671 9.1576 0.0 0
M  V30 61 C -3.6861 10.5399 0.0 0
M  V30 62 C -2.6493 11.9798 0.0 0
M  V30 63 C -2.6493 8.0633 0.0 0
M  V30 64 C -0.2303 10.0216 0.0 0
M  V30 65 C -5.0684 10.0216 0.0 0
M  V30 66 C -6.4507 10.8855 0.0 0
M  V30 67 C -7.8329 10.3671 0.0 0
M  V30 68 C -9.2152 11.2311 0.0 0
M  V30 69 C -10.5975 10.7127 0.0 0
M  V30 70 C -11.9798 11.5767 0.0 0
M  V30 71 C -13.3621 11.0583 0.0 0
M  V30 72 C -14.7444 11.9222 0.0 0
M  V30 73 C -16.1267 11.4039 0.0 0
M  V30 74 C -17.509 12.2678 0.0 0
M  V30 75 C -18.8913 11.7494 0.0 0
M  V30 76 Si -4.6076 25.342 0.0 0
M  V30 77 O -3.7437 26.5515 0.0 0
M  V30 78 O -5.8171 24.4781 0.0 0
M  V30 79 O -3.5133 24.766 0.0 0
M  V30 80 C -6.0475 26.2635 0.0 0
M  V30 81 C -4.9532 27.761 0.0 0
M  V30 82 C -4.9532 23.6141 0.0 0
M  V30 83 C -2.419 25.6876 0.0 0
M  V30 84 C -7.4874 25.6876 0.0 0
M  V30 85 C -8.9273 26.6091 0.0 0
M  V30 86 C -10.3671 26.0331 0.0 0
M  V30 87 C -11.807 26.9547 0.0 0
M  V30 88 C -13.2469 26.3787 0.0 0
M  V30 89 C -14.6868 27.3002 0.0 0
M  V30 90 C -16.1267 26.7243 0.0 0
M  V30 91 Si -7.3722 41.4687 0.0 0
M  V30 92 O -6.5082 42.6782 0.0 0
M  V30 93 O -8.5817 40.6048 0.0 0
M  V30 94 O -6.2779 40.8928 0.0 0
M  V30 95 C -8.8121 42.3903 0.0 0
M  V30 96 C -7.7178 43.8877 0.0 0
M  V30 97 C -7.7178 39.7409 0.0 0
M  V30 98 C -5.1835 41.8143 0.0 0
M  V30 99 C -10.252 41.8143 0.0 0
M  V30 100 C -11.6918 42.7358 0.0 0
M  V30 101 C -13.1317 42.1599 0.0 0
M  V30 102 C -14.5716 43.0814 0.0 0
M  V30 103 C -16.0115 42.5055 0.0 0
M  V30 104 Si -5.5291 49.7625 0.0 0
M  V30 105 O -6.7386 48.8986 0.0 0
M  V30 106 O -4.4348 49.1865 0.0 0
M  V30 107 O -4.6652 50.972 0.0 0
M  V30 108 C -6.969 50.684 0.0 0
M  V30 109 C -5.8747 48.0346 0.0 0
M  V30 110 C -3.3405 50.1081 0.0 0
M  V30 111 C -5.8747 52.1815 0.0 0
M  V30 112 C -8.4089 50.1081 0.0 0
M  V30 113 C -4.55 48.2074 0.0 0
M  V30 114 C -2.2462 49.5321 0.0 0
M  V30 115 C -5.0108 53.391 0.0 0
M  V30 116 Si -11.9798 50.2233 0.0 0
M  V30 117 O -11.1159 51.4328 0.0 0
M  V30 118 O -13.1893 49.3593 0.0 0
M  V30 119 O -10.8855 49.6473 0.0 0
M  V30 120 C -13.4197 51.1448 0.0 0
M  V30 121 C -12.3254 52.6423 0.0 0
M  V30 122 C -12.3254 48.4954 0.0 0
M  V30 123 C -9.7912 50.5688 0.0 0
M  V30 124 C -14.8596 50.5688 0.0 0
M  V30 125 Si -5.9899 58.517 0.0 0
M  V30 126 O -7.1994 57.6531 0.0 0
M  V30 127 O -4.8956 57.9411 0.0 0
M  V30 128 O -5.126 59.7265 0.0 0
M  V30 129 C -7.4298 59.4385 0.0 0
M  V30 130 C -6.3355 56.7892 0.0 0
M  V30 131 C -3.8013 58.8626 0.0 0
M  V30 132 C -6.3355 60.936 0.0 0
M  V30 133 C -5.0108 56.9619 0.0 0
M  V30 134 C -2.7069 58.2866 0.0 0
M  V30 135 C -5.4715 62.1455 0.0 0
M  V30 136 Si -12.4406 58.9778 0.0 0
M  V30 137 O -11.5767 60.1873 0.0 0
M  V30 138 O -13.6501 58.1138 0.0 0
M  V30 139 O -11.3463 58.4018 0.0 0
M  V30 140 C -13.8805 59.8993 0.0 0
M  V30 141 C -12.7862 61.3968 0.0 0
M  V30 142 C -12.7862 57.2499 0.0 0
M  V30 143 C -10.252 59.3234 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 23 24
M  V30 23 1 23 25
M  V30 24 1 23 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 25 29
M  V30 28 1 26 30
M  V30 29 1 27 31
M  V30 30 1 28 32
M  V30 31 1 29 33
M  V30 32 1 30 34
M  V30 33 1 31 35
M  V30 34 1 35 36
M  V30 35 1 36 37
M  V30 36 1 37 38
M  V30 37 1 38 39
M  V30 38 1 39 40
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 41 44
M  V30 42 1 41 45
M  V30 43 1 42 46
M  V30 44 1 43 47
M  V30 45 1 44 48
M  V30 46 1 45 49
M  V30 47 1 46 50
M  V30 48 1 47 51
M  V30 49 1 48 52
M  V30 50 1 49 53
M  V30 51 1 53 54
M  V30 52 1 54 55
M  V30 53 1 55 56
M  V30 54 1 57 58
M  V30 55 1 57 59
M  V30 56 1 57 60
M  V30 57 1 57 61
M  V30 58 1 58 62
M  V30 59 1 59 63
M  V30 60 1 60 64
M  V30 61 1 61 65
M  V30 62 1 65 66
M  V30 63 1 66 67
M  V30 64 1 67 68
M  V30 65 1 68 69
M  V30 66 1 69 70
M  V30 67 1 70 71
M  V30 68 1 71 72
M  V30 69 1 72 73
M  V30 70 1 73 74
M  V30 71 1 74 75
M  V30 72 1 76 77
M  V30 73 1 76 78
M  V30 74 1 76 79
M  V30 75 1 76 80
M  V30 76 1 77 81
M  V30 77 1 78 82
M  V30 78 1 79 83
M  V30 79 1 80 84
M  V30 80 1 84 85
M  V30 81 1 85 86
M  V30 82 1 86 87
M  V30 83 1 87 88
M  V30 84 1 88 89
M  V30 85 1 89 90
M  V30 86 1 91 92
M  V30 87 1 91 93
M  V30 88 1 91 94
M  V30 89 1 91 95
M  V30 90 1 92 96
M  V30 91 1 93 97
M  V30 92 1 94 98
M  V30 93 1 95 99
M  V30 94 1 99 100
M  V30 95 1 100 101
M  V30 96 1 101 102
M  V30 97 1 102 103
M  V30 98 1 104 105
M  V30 99 1 104 106
M  V30 100 1 104 107
M  V30 101 1 104 108
M  V30 102 1 105 109
M  V30 103 1 106 110
M  V30 104 1 107 111
M  V30 105 1 108 112
M  V30 106 1 109 113
M  V30 107 1 110 114
M  V30 108 1 111 115
M  V30 109 1 116 117
M  V30 110 1 116 118
M  V30 111 1 116 119
M  V30 112 1 116 120
M  V30 113 1 117 121
M  V30 114 1 118 122
M  V30 115 1 119 123
M  V30 116 1 120 124
M  V30 117 1 125 126
M  V30 118 1 125 127
M  V30 119 1 125 128
M  V30 120 1 125 129
M  V30 121 1 126 130
M  V30 122 1 127 131
M  V30 123 1 128 132
M  V30 124 1 130 133
M  V30 125 1 131 134
M  V30 126 1 132 135
M  V30 127 1 136 137
M  V30 128 1 136 138
M  V30 129 1 136 139
M  V30 130 1 136 140
M  V30 131 1 137 141
M  V30 132 1 138 142
M  V30 133 1 139 143
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000729A1-20220106-C00011

>  <Row No>
522

$$$$
US20220000729A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.1121 0.6563 0.0 0
M  V30 3 O -2.2243 0.0911 0.0 0
M  V30 4 C -1.1668 1.9691 0.0 0 CFG=2
M  V30 5 C -2.279 -1.1121 0.0 0
M  V30 6 C -2.8625 2.0238 0.0 0
M  V30 7 C 1.1304 2.0238 0.0 0
M  V30 8 C -4.1753 2.0785 0.0 0
M  V30 9 C -3.0631 -2.3337 0.0 0
M  V30 10 C -1.4768 -2.279 0.0 0
M  V30 11 C -4.3758 -2.279 0.0 0
M  V30 12 C 0.2552 -2.2243 0.0 0
M  V30 13 C -3.5006 -2.3337 0.0 0
M  V30 14 C -0.5834 -2.3337 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7 CFG=3
M  V30 7 1 6 8
M  V30 8 1 9 10
M  V30 9 1 9 11
M  V30 10 1 10 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 4)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000729A1-20220106-C00012

>  <Row No>
523

$$$$
US20220000729A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.1121 0.6563 0.0 0
M  V30 3 O -2.2243 0.0911 0.0 0
M  V30 4 C -1.1668 1.9691 0.0 0 CFG=2
M  V30 5 C -2.279 -1.1121 0.0 0
M  V30 6 C -2.8625 2.0238 0.0 0
M  V30 7 C 1.1304 2.0238 0.0 0
M  V30 8 C -4.1753 2.0785 0.0 0
M  V30 9 C -3.0631 -2.3337 0.0 0
M  V30 10 C -1.4768 -2.279 0.0 0
M  V30 11 C -4.3758 -2.279 0.0 0
M  V30 12 C 0.2552 -2.2243 0.0 0
M  V30 13 C -3.5006 -2.3337 0.0 0
M  V30 14 C -0.5834 -2.3337 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7 CFG=3
M  V30 7 1 6 8
M  V30 8 1 9 10
M  V30 9 1 9 11
M  V30 10 1 10 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 4)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000729A1-20220106-C00013

>  <Row No>
524

$$$$
US20220000729A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Ra 0.0 0.0 0.0 0 VAL=2
M  V30 2 O -0.0408 -1.6627 0.0 0
M  V30 3 C -0.0817 -1.9353 0.0 0
M  V30 4 Si -0.1226 -3.598 0.0 0
M  V30 5 O 1.54 -3.5571 0.0 0
M  V30 6 O -0.1635 -5.2607 0.0 0
M  V30 7 O -1.8671 -3.5571 0.0 0 CHG=-1
M  V30 8 C 3.2027 -3.5162 0.0 0
M  V30 9 C -0.2044 -6.9234 0.0 0
M  V30 10 Rb -3.816 -3.489 0.0 0 CHG=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 4 1 4 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00039001.cdx

>  <name>
US20220000729A1-20220106-C00014

>  <Row No>
525

$$$$
US20220000734A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000734A1-20220106-C00001

>  <Row No>
526

$$$$
US20220000734A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000734A1-20220106-C00002

>  <Row No>
527

$$$$
US20220000734A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000734A1-20220106-C00003

>  <Row No>
528

$$$$
US20220000734A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2518 -0.7272 0.0 0
M  V30 3 O 2.5036 0.0476 0.0 0
M  V30 4 C 1.216 -2.1817 0.0 0
M  V30 5 C -0.1072 -2.9089 0.0 0
M  V30 6 C -0.143 -4.3634 0.0 0
M  V30 7 C -1.4664 -5.0907 0.0 0
M  V30 8 C -2.7897 -4.3158 0.0 0
M  V30 9 C -4.1131 -5.043 0.0 0 CFG=1
M  V30 10 O -4.1488 -6.4975 0.0 0
M  V30 11 C -5.4364 -4.2561 0.0 0
M  V30 12 C -5.4722 -2.7301 0.0 0
M  V30 13 C -6.7956 -1.9552 0.0 0
M  V30 14 C -8.1189 -2.6824 0.0 0
M  V30 15 C -9.4423 -1.9075 0.0 0
M  V30 16 C -10.7656 -2.6347 0.0 0
M  V30 17 C -10.8014 -4.0892 0.0 0 CFG=1
M  V30 18 O -9.5496 -4.8165 0.0 0
M  V30 19 C -12.1247 -4.8165 0.0 0
M  V30 20 C -12.1605 -6.271 0.0 0
M  V30 21 C -13.4839 -6.9982 0.0 0
M  V30 22 C -14.8072 -6.2233 0.0 0
M  V30 23 C -16.1306 -6.9505 0.0 0
M  V30 24 C -17.4539 -6.1756 0.0 0
M  V30 25 C -18.7773 -6.9029 0.0 0
M  V30 26 C -20.1006 -6.1279 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 4 5
M  V30 5 1 5 6
M  V30 6 2 6 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 9 10 CFG=1
M  V30 10 1 9 11
M  V30 11 2 11 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18 CFG=1
M  V30 18 1 17 19
M  V30 19 1 19 20
M  V30 20 2 20 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 2 23 24
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 9 17)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000734A1-20220106-C00004

>  <Row No>
529

$$$$
US20220000734A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000734A1-20220106-C00005

>  <Row No>
530

$$$$
US20220000736A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000736A1-20220106-C00001

>  <Row No>
531

$$$$
US20220000736A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000736A1-20220106-C00002

>  <Row No>
532

$$$$
US20220000736A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000736A1-20220106-C00003

>  <Row No>
533

$$$$
US20220000736A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000736A1-20220106-C00004

>  <Row No>
534

$$$$
US20220000737A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 51 54 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0 CHG=1
M  V30 2 C -0.8706 -1.2479 0.0 0
M  V30 3 C 1.4801 0.087 0.0 0
M  V30 4 C -0.8706 1.4221 0.0 0
M  V30 5 C -0.1741 -2.4959 0.0 0
M  V30 6 C 2.1767 -1.1609 0.0 0
M  V30 7 C 1.306 -2.4088 0.0 0
M  V30 8 C 2.0025 -3.6568 0.0 0
M  V30 9 N 2.6991 -4.9048 0.0 0
M  V30 10 N 3.3956 -6.1528 0.0 0
M  V30 11 C 4.0922 -7.4008 0.0 0
M  V30 12 C 2.2057 -7.1686 0.0 0
M  V30 13 C 3.2215 -8.6487 0.0 0
M  V30 14 C 5.5723 -7.3137 0.0 0
M  V30 15 C 3.918 -9.8967 0.0 0
M  V30 16 C 6.2689 -8.5617 0.0 0
M  V30 17 C 5.3982 -9.8096 0.0 0
M  V30 18 N 2.3218 29.7193 0.0 0 CHG=1
M  V30 19 C 1.335 28.5584 0.0 0
M  V30 20 C 1.335 31.0543 0.0 0
M  V30 21 C 3.7439 30.2127 0.0 0
M  V30 22 N 2.0315 27.3104 0.0 0
M  V30 23 N -0.2321 29.1388 0.0 0
M  V30 24 C -0.2321 30.648 0.0 0
M  V30 25 N 2.7281 26.0624 0.0 0
M  V30 26 C -1.6542 28.4423 0.0 0
M  V30 27 C 3.4246 24.8144 0.0 0
M  V30 28 C 2.554 23.5664 0.0 0
M  V30 29 C 4.9048 24.9015 0.0 0
M  V30 30 C 3.2505 22.3185 0.0 0
M  V30 31 C 5.6013 23.6535 0.0 0
M  V30 32 C 4.7307 22.4055 0.0 0
M  V30 33 N 5.4272 21.1576 0.0 0
M  V30 34 C 6.9074 21.2446 0.0 0
M  V30 35 C 4.5565 19.9096 0.0 0
M  V30 36 N 2.3218 14.8596 0.0 0 CHG=1
M  V30 37 C 1.335 13.6987 0.0 0
M  V30 38 C 1.335 16.1947 0.0 0
M  V30 39 C 3.7439 15.353 0.0 0
M  V30 40 N 2.0315 12.4507 0.0 0
M  V30 41 N -0.2321 14.2792 0.0 0
M  V30 42 C -0.2321 15.7883 0.0 0
M  V30 43 N 2.7281 11.2027 0.0 0
M  V30 44 C -1.6542 13.5826 0.0 0
M  V30 45 C 3.4246 9.9548 0.0 0
M  V30 46 C 2.554 8.7068 0.0 0
M  V30 47 C 4.9048 10.0418 0.0 0
M  V30 48 C 3.2505 7.4588 0.0 0
M  V30 49 C 5.6013 8.7939 0.0 0
M  V30 50 C 4.7307 7.5459 0.0 0
M  V30 51 N 5.4272 6.2979 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 2 3 6
M  V30 6 2 5 7
M  V30 7 1 7 8
M  V30 8 2 8 9 CFG=2
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 10 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 2 15 17
M  V30 17 2 18 19
M  V30 18 1 18 20
M  V30 19 1 18 21
M  V30 20 1 19 22
M  V30 21 1 19 23
M  V30 22 2 20 24
M  V30 23 2 22 25 CFG=2
M  V30 24 1 23 26
M  V30 25 1 25 27
M  V30 26 2 27 28
M  V30 27 1 27 29
M  V30 28 1 28 30
M  V30 29 2 29 31
M  V30 30 2 30 32
M  V30 31 1 32 33
M  V30 32 1 33 34
M  V30 33 1 33 35
M  V30 34 2 36 37
M  V30 35 1 36 38
M  V30 36 1 36 39
M  V30 37 1 37 40
M  V30 38 1 37 41
M  V30 39 2 38 42
M  V30 40 2 40 43 CFG=2
M  V30 41 1 41 44
M  V30 42 1 43 45
M  V30 43 2 45 46
M  V30 44 1 45 47
M  V30 45 1 46 48
M  V30 46 2 47 49
M  V30 47 2 48 50
M  V30 48 1 50 51
M  V30 49 1 6 7
M  V30 50 1 16 17
M  V30 51 1 23 24
M  V30 52 1 31 32
M  V30 53 1 41 42
M  V30 54 1 49 50
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000737A1-20220106-C00002

>  <Row No>
535

$$$$
US20220000737A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=10
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000737A1-20220106-C00003

>  <Row No>
536

$$$$
US20220000737A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=16
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000737A1-20220106-C00004

>  <Row No>
537

$$$$
US20220000737A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 72 79 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0457 1.5245 0.0 0
M  V30 3 C -1.3721 2.3173 0.0 0
M  V30 4 C 1.1891 2.3173 0.0 0
M  V30 5 C -1.4178 3.8418 0.0 0
M  V30 6 C -2.6984 1.616 0.0 0
M  V30 7 C 1.1434 3.8418 0.0 0
M  V30 8 C 2.424 1.616 0.0 0
M  V30 9 C -0.1829 4.6346 0.0 0
M  V30 10 C -2.7442 4.6346 0.0 0
M  V30 11 C -4.0248 2.4088 0.0 0
M  V30 12 C -2.7442 0.1829 0.0 0
M  V30 13 C 2.3783 4.6346 0.0 0
M  V30 14 C 3.6589 2.4088 0.0 0
M  V30 15 C 2.3783 0.1829 0.0 0
M  V30 16 O -0.2286 6.1592 0.0 0
M  V30 17 N -2.7899 6.1592 0.0 0
M  V30 18 C -4.0705 3.9333 0.0 0
M  V30 19 ? -5.3512 1.7075 0.0 0 MASS=26
M  V30 20 C 3.6132 3.9333 0.0 0
M  V30 21 ? 2.3325 6.1592 0.0 0 MASS=25
M  V30 22 ? 4.8938 1.7075 0.0 0 MASS=23
M  V30 23 C -2.8356 7.6837 0.0 0
M  V30 24 ? -4.1163 5.4579 0.0 0 MASS=28
M  V30 25 ? -5.3969 4.7261 0.0 0 MASS=27
M  V30 26 ? 4.8481 4.7261 0.0 0 MASS=24
M  V30 27 C -4.162 8.4765 0.0 0
M  V30 28 C -1.6007 8.4765 0.0 0
M  V30 29 C -5.4884 7.7752 0.0 0
M  V30 30 C -4.2077 10.0011 0.0 0
M  V30 31 C -1.6465 10.0011 0.0 0
M  V30 32 ? -0.3658 7.7752 0.0 0 MASS=27
M  V30 33 O -5.5341 6.3421 0.0 0
M  V30 34 C -6.8147 8.568 0.0 0
M  V30 35 C -5.5341 10.7938 0.0 0
M  V30 36 C -2.9728 10.7938 0.0 0
M  V30 37 ? -0.4116 10.7938 0.0 0 MASS=26
M  V30 38 C -6.8605 10.0925 0.0 0
M  V30 39 C -8.1411 7.8667 0.0 0
M  V30 40 O -5.5798 12.3184 0.0 0
M  V30 41 C -3.0186 12.3184 0.0 0
M  V30 42 C -8.1868 10.8853 0.0 0
M  V30 43 C -9.4675 8.6595 0.0 0
M  V30 44 ? -8.1868 6.4336 0.0 0 MASS=25
M  V30 45 C -9.5132 10.184 0.0 0
M  V30 46 ? -8.2326 12.4099 0.0 0 MASS=22
M  V30 47 ? -10.7938 7.9582 0.0 0 MASS=24
M  V30 48 ? -10.8396 10.9768 0.0 0 MASS=23
M  V30 49 O -5.6103 15.6115 0.0 0
M  V30 50 C -5.6561 17.136 0.0 0
M  V30 51 C -4.4212 17.9288 0.0 0
M  V30 52 C -6.9824 17.9288 0.0 0
M  V30 53 C -4.4669 19.4533 0.0 0
M  V30 54 C -3.1863 17.2275 0.0 0
M  V30 55 C -7.0282 19.4533 0.0 0
M  V30 56 C -8.3088 17.2275 0.0 0
M  V30 57 C -5.7933 20.2461 0.0 0
M  V30 58 C -3.232 20.2461 0.0 0
M  V30 59 C -1.9514 18.0203 0.0 0
M  V30 60 C -3.232 15.7944 0.0 0
M  V30 61 C -8.3545 20.2461 0.0 0
M  V30 62 C -9.6352 18.0203 0.0 0
M  V30 63 ? -8.3545 15.7944 0.0 0 MASS=25
M  V30 64 O -5.839 21.7707 0.0 0
M  V30 65 C -1.9971 19.5448 0.0 0
M  V30 66 C -3.2778 21.7707 0.0 0
M  V30 67 ? -0.7165 17.319 0.0 0 MASS=27
M  V30 68 C -9.6809 19.5448 0.0 0
M  V30 69 ? -8.4003 21.7707 0.0 0 MASS=22
M  V30 70 ? -10.9615 17.319 0.0 0 MASS=24
M  V30 71 ? -0.7622 20.3376 0.0 0 MASS=26
M  V30 72 ? -11.0073 20.3376 0.0 0 MASS=23
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 2 8 14
M  V30 14 1 8 15
M  V30 15 2 9 16
M  V30 16 1 10 17
M  V30 17 2 10 18
M  V30 18 1 11 19
M  V30 19 2 13 20
M  V30 20 1 13 21
M  V30 21 1 14 22
M  V30 22 1 17 23
M  V30 23 1 17 24
M  V30 24 1 18 25
M  V30 25 1 20 26
M  V30 26 2 23 27
M  V30 27 1 23 28
M  V30 28 1 27 29
M  V30 29 1 27 30
M  V30 30 2 28 31
M  V30 31 1 28 32
M  V30 32 2 29 33
M  V30 33 1 29 34
M  V30 34 1 30 35
M  V30 35 2 30 36
M  V30 36 1 31 37
M  V30 37 2 34 38
M  V30 38 1 34 39
M  V30 39 2 35 40
M  V30 40 1 36 41
M  V30 41 1 38 42
M  V30 42 2 39 43
M  V30 43 1 39 44
M  V30 44 2 42 45
M  V30 45 1 42 46
M  V30 46 1 43 47
M  V30 47 1 45 48
M  V30 48 2 49 50
M  V30 49 1 50 51
M  V30 50 1 50 52
M  V30 51 2 51 53
M  V30 52 1 51 54
M  V30 53 2 52 55
M  V30 54 1 52 56
M  V30 55 1 53 57
M  V30 56 1 53 58
M  V30 57 2 54 59
M  V30 58 1 54 60
M  V30 59 1 55 61
M  V30 60 2 56 62
M  V30 61 1 56 63
M  V30 62 2 57 64
M  V30 63 2 58 65
M  V30 64 1 58 66
M  V30 65 1 59 67
M  V30 66 2 61 68
M  V30 67 1 61 69
M  V30 68 1 62 70
M  V30 69 1 65 71
M  V30 70 1 68 72
M  V30 71 1 7 9
M  V30 72 1 11 18
M  V30 73 1 14 20
M  V30 74 1 31 36
M  V30 75 1 35 38
M  V30 76 1 43 45
M  V30 77 1 55 57
M  V30 78 1 59 65
M  V30 79 1 62 68
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000737A1-20220106-C00005

>  <Row No>
538

$$$$
US20220000737A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 59 56 0 0 0
M  V30 BEGIN ATOM
M  V30 1 W 0.0 0.0 0.0 0 VAL=2
M  V30 2 C 1.3031 0.1028 0.0 0
M  V30 3 C -0.823 -1.1316 0.0 0
M  V30 4 S 3.395 0.2057 0.0 0
M  V30 5 O 3.2922 1.7146 0.0 0
M  V30 6 O 3.2922 -1.0974 0.0 0
M  V30 7 O 4.6982 0.3086 0.0 0 CHG=-1
M  V30 8 S 0.2743 8.5048 0.0 0
M  V30 9 O -1.2345 8.6077 0.0 0
M  V30 10 O 1.5775 8.6077 0.0 0
M  V30 11 O 0.1714 10.0138 0.0 0 CHG=-1
M  V30 12 C 0.1714 7.2017 0.0 0
M  V30 13 O 5.2126 9.8766 0.0 0
M  V30 14 N 4.3896 8.7449 0.0 0 CHG=1
M  V30 15 O 2.8806 8.8478 0.0 0 CHG=-1
M  V30 16 C 5.0069 7.6132 0.0 0
M  V30 17 C 4.1838 6.4815 0.0 0
M  V30 18 C 6.31 7.7161 0.0 0
M  V30 19 N 2.6749 6.5844 0.0 0
M  V30 20 C 4.8011 5.3498 0.0 0
M  V30 21 C 6.9273 6.5844 0.0 0
M  V30 22 C 1.1659 6.6873 0.0 0
M  V30 23 C 2.572 5.2812 0.0 0
M  V30 24 C 6.1043 5.4527 0.0 0
M  V30 25 C 8.2305 6.6873 0.0 0
M  V30 26 C 0.3429 5.5556 0.0 0
M  V30 27 C 0.3429 8.0247 0.0 0
M  V30 28 C -1.1659 5.6584 0.0 0
M  V30 29 C -1.1659 8.1276 0.0 0
M  V30 30 C -1.989 6.9959 0.0 0
M  V30 31 N -3.4979 7.0988 0.0 0
M  V30 32 C -5.0069 7.2017 0.0 0
M  V30 33 C -3.6008 5.7956 0.0 0
M  V30 34 C -5.8299 6.07 0.0 0
M  V30 35 C -5.8299 8.5391 0.0 0
M  V30 36 C -7.3388 6.1729 0.0 0
M  V30 37 C -7.3388 8.642 0.0 0
M  V30 38 C -8.1619 7.5103 0.0 0
M  V30 39 O -3.2922 -4.6639 0.0 0
M  V30 40 N -2.1605 -3.8409 0.0 0 CHG=1
M  V30 41 O -1.0288 -4.4582 0.0 0 CHG=-1
M  V30 42 C -2.2633 -2.3319 0.0 0
M  V30 43 C -3.6008 -1.5089 0.0 0
M  V30 44 C -1.1316 -1.5089 0.0 0
M  V30 45 C -3.7037 0.0 0.0 0
M  V30 46 C -4.9383 -2.1262 0.0 0
M  V30 47 C -1.2345 0.0 0.0 0
M  V30 48 C -2.572 0.823 0.0 0
M  V30 49 C -5.0412 0.823 0.0 0
M  V30 50 C -6.2757 -1.3031 0.0 0
M  V30 51 C -6.3786 0.2057 0.0 0
M  V30 52 C -6.0357 6.8587 0.0 0
M  V30 53 C -7.3731 7.6818 0.0 0
M  V30 54 C -2.1948 -1.0974 0.0 0
M  V30 55 C -6.5844 -0.9945 0.0 0
M  V30 56 C 6.0357 5.487 0.0 0
M  V30 57 ? 5.9328 4.1838 0.0 0 MASS=32
M  V30 58 C 0.2743 5.487 0.0 0
M  V30 59 ? 0.1714 4.1838 0.0 0 MASS=31
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 2 8 9
M  V30 8 2 8 10
M  V30 9 1 8 11
M  V30 10 1 8 12
M  V30 11 2 13 14
M  V30 12 1 14 15
M  V30 13 1 14 16
M  V30 14 2 16 17
M  V30 15 1 16 18
M  V30 16 1 17 19
M  V30 17 1 17 20
M  V30 18 2 18 21
M  V30 19 1 19 22
M  V30 20 1 19 23
M  V30 21 2 20 24
M  V30 22 1 21 25
M  V30 23 2 22 26
M  V30 24 1 22 27
M  V30 25 1 26 28
M  V30 26 2 27 29
M  V30 27 2 28 30
M  V30 28 1 30 31
M  V30 29 1 31 32
M  V30 30 1 31 33
M  V30 31 2 32 34
M  V30 32 1 32 35
M  V30 33 1 34 36
M  V30 34 2 35 37
M  V30 35 2 36 38
M  V30 36 2 39 40
M  V30 37 1 40 41
M  V30 38 1 40 42
M  V30 39 2 42 43
M  V30 40 1 42 44
M  V30 41 1 43 45
M  V30 42 1 43 46
M  V30 43 2 44 47
M  V30 44 2 45 48
M  V30 45 1 45 49
M  V30 46 1 46 50
M  V30 47 1 49 51
M  V30 48 1 52 53
M  V30 49 1 54 55
M  V30 50 1 56 57
M  V30 51 1 58 59
M  V30 52 1 21 24
M  V30 53 1 29 30
M  V30 54 1 37 38
M  V30 55 1 47 48
M  V30 56 1 50 51
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000737A1-20220106-C00006

>  <Row No>
539

$$$$
US20220000737A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -0.0348 -1.4657 0.0 0
M  V30 3 C -1.3377 0.791 0.0 0
M  V30 4 C 1.2679 0.791 0.0 0
M  V30 5 C -1.3726 -2.1636 0.0 0
M  V30 6 C 1.233 -2.1636 0.0 0
M  V30 7 C -2.6754 0.093 0.0 0
M  V30 8 C -2.7103 -1.3726 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 5 8
M  V30 8 1 7 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000737A1-20220106-C00007

>  <Row No>
540

$$$$
US20220000737A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 43 35 0 0 0
M  V30 BEGIN ATOM
M  V30 1 I 0.0 0.0 0.0 0
M  V30 2 N 4.8668 6.3268 0.0 0 CHG=1
M  V30 3 C 3.5406 5.609 0.0 0
M  V30 4 ? 6.12 5.609 0.0 0 MASS=36
M  V30 5 ? 4.8303 7.8599 0.0 0 MASS=35
M  V30 6 C 2.2144 6.3998 0.0 0
M  V30 7 C 3.5041 4.1489 0.0 0
M  V30 8 C 0.8881 5.682 0.0 0
M  V30 9 C 2.1779 3.4311 0.0 0
M  V30 10 C 0.8516 4.2219 0.0 0
M  V30 11 C -0.4745 3.5041 0.0 0
M  V30 12 C -1.8007 4.2949 0.0 0
M  V30 13 C -0.511 2.044 0.0 0
M  V30 14 C -1.8372 5.828 0.0 0
M  V30 15 C -3.1269 3.5771 0.0 0
M  V30 16 C -1.8372 1.3262 0.0 0
M  V30 17 C 0.7421 1.3262 0.0 0
M  V30 18 C -3.1634 6.6188 0.0 0
M  V30 19 C -4.4531 4.3679 0.0 0
M  V30 20 C -1.8372 -0.146 0.0 0
M  V30 21 C 0.7178 -0.1703 0.0 0
M  V30 22 C -4.4896 5.901 0.0 0
M  V30 23 C -0.6205 -0.8516 0.0 0
M  V30 24 N -5.8158 6.6797 0.0 0
M  V30 25 ? -5.8523 8.2127 0.0 0 MASS=33
M  V30 26 ? -7.142 5.9618 0.0 0 MASS=23
M  V30 27 C 0.3893 0.1946 0.0 0
M  V30 28 ? 1.8858 0.219 0.0 0 MASS=44
M  V30 29 C 0.0 -0.3893 0.0 0
M  V30 30 ? 0.73 -1.606 0.0 0 MASS=43
M  V30 31 C -0.6813 -0.3893 0.0 0
M  V30 32 ? -1.46 -1.606 0.0 0 MASS=42
M  V30 33 C -1.0707 0.1946 0.0 0
M  V30 34 ? -2.628 0.219 0.0 0 MASS=41
M  V30 35 C 2.628 4.0881 0.0 0
M  V30 36 ? 3.3459 2.8349 0.0 0 MASS=40
M  V30 37 C 1.8493 5.4508 0.0 0
M  V30 38 ? 1.0585 6.777 0.0 0 MASS=39
M  V30 39 C -3.4067 4.0881 0.0 0
M  V30 40 ? -4.1976 2.8349 0.0 0 MASS=38
M  V30 41 C -2.628 5.4508 0.0 0
M  V30 42 ? -1.9102 6.777 0.0 0 MASS=37
M  V30 43 H 2.336 4.8668 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 2 3
M  V30 2 1 2 4
M  V30 3 1 2 5
M  V30 4 1 3 6
M  V30 5 1 3 7
M  V30 6 2 6 8
M  V30 7 2 7 9
M  V30 8 1 8 10
M  V30 9 2 10 11
M  V30 10 1 11 12
M  V30 11 1 11 13
M  V30 12 2 12 14
M  V30 13 1 12 15
M  V30 14 2 13 16
M  V30 15 1 13 17
M  V30 16 1 14 18
M  V30 17 2 15 19
M  V30 18 1 16 20
M  V30 19 2 17 21
M  V30 20 2 18 22
M  V30 21 2 20 23
M  V30 22 1 22 24
M  V30 23 1 24 25
M  V30 24 1 24 26
M  V30 25 1 27 28
M  V30 26 1 29 30
M  V30 27 1 31 32
M  V30 28 1 33 34
M  V30 29 1 35 36
M  V30 30 1 37 38
M  V30 31 1 39 40
M  V30 32 1 41 42
M  V30 33 1 9 10
M  V30 34 1 19 22
M  V30 35 1 21 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000737A1-20220106-C00008

>  <Row No>
541

$$$$
US20220000737A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 34 36 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -0.0362 -1.4741 0.0 0
M  V30 3 C 1.2687 0.7733 0.0 0
M  V30 4 C -1.317 0.7612 0.0 0
M  V30 5 C 1.2325 -2.1991 0.0 0
M  V30 6 C -1.3775 -2.1991 0.0 0
M  V30 7 C 1.2566 2.2716 0.0 0
M  V30 8 C 2.5375 0.0483 0.0 0
M  V30 9 C -1.3291 2.2716 0.0 0
M  V30 10 C -2.6341 0.0241 0.0 0
M  V30 11 C 1.1962 -3.6733 0.0 0
M  V30 12 C 2.7066 -2.1629 0.0 0
M  V30 13 C -1.4137 -3.6733 0.0 0
M  V30 14 ? -2.7187 -1.4137 0.0 0 MASS=49
M  V30 15 C 2.5254 3.045 0.0 0
M  V30 16 C -0.0604 3.045 0.0 0
M  V30 17 C 3.8062 0.8337 0.0 0
M  V30 18 C -2.6462 3.045 0.0 0
M  V30 19 C -3.9512 0.7975 0.0 0
M  V30 20 C -0.145 -4.4104 0.0 0
M  V30 21 ? 2.465 -4.4104 0.0 0 MASS=52
M  V30 22 C 3.4437 -0.8216 0.0 0
M  V30 23 C 3.4437 -3.4316 0.0 0
M  V30 24 ? -2.755 -4.4104 0.0 0 MASS=50
M  V30 25 C 3.7941 2.32 0.0 0
M  V30 26 ? 2.4891 4.5916 0.0 0 MASS=47
M  V30 27 ? 5.075 0.1087 0.0 0 MASS=48
M  V30 28 C -3.9633 2.3079 0.0 0
M  V30 29 ? -2.6825 4.5916 0.0 0 MASS=45
M  V30 30 ? -5.2925 0.0725 0.0 0 MASS=46
M  V30 31 ? -0.1812 -5.8846 0.0 0 MASS=51
M  V30 32 C 5.0629 3.0933 0.0 0
M  V30 33 ? -5.2804 3.0812 0.0 0
M  V30 34 C 5.22 -3.48 0.0 0 CHG=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 2 2 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 3 8
M  V30 8 2 4 9
M  V30 9 1 4 10
M  V30 10 1 5 11
M  V30 11 1 5 12
M  V30 12 2 6 13
M  V30 13 1 6 14
M  V30 14 2 7 15
M  V30 15 1 7 16
M  V30 16 2 8 17
M  V30 17 1 9 18
M  V30 18 2 10 19
M  V30 19 2 11 20
M  V30 20 1 11 21
M  V30 21 2 12 22
M  V30 22 1 12 23
M  V30 23 1 13 24
M  V30 24 1 15 25
M  V30 25 1 15 26
M  V30 26 1 17 27
M  V30 27 2 18 28
M  V30 28 1 18 29
M  V30 29 1 19 30
M  V30 30 1 20 31
M  V30 31 2 25 32
M  V30 32 1 28 33
M  V30 33 1 9 16
M  V30 34 1 13 20
M  V30 35 1 17 25
M  V30 36 1 19 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000737A1-20220106-C00009

>  <Row No>
542

$$$$
US20220000737A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 33 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C 1.3955 -0.4331 0.0 0
M  V30 3 C -0.9143 -1.179 0.0 0
M  V30 4 C -0.5052 1.4677 0.0 0
M  V30 5 C 2.6588 0.3368 0.0 0
M  V30 6 C 1.3594 -1.9008 0.0 0
M  V30 7 C -2.4542 -1.1429 0.0 0
M  V30 8 C -0.0721 -2.358 0.0 0
M  V30 9 C 3.922 -0.3849 0.0 0
M  V30 10 ? 2.6227 1.8768 0.0 0 MASS=60
M  V30 11 C 2.6227 -2.6227 0.0 0
M  V30 12 N -3.3686 -2.3219 0.0 0
M  V30 13 C -3.3686 0.1082 0.0 0
M  V30 14 C -0.8541 -3.6212 0.0 0
M  V30 15 C 3.8859 -1.8527 0.0 0
M  V30 16 ? 5.1853 0.3849 0.0 0 MASS=59
M  V30 17 ? 2.5866 -4.0904 0.0 0 MASS=57
M  V30 18 C -4.8364 -1.8166 0.0 0
M  V30 19 C -2.6467 -3.5851 0.0 0
M  V30 20 C -4.8364 -0.3248 0.0 0
M  V30 21 C -2.6467 1.4437 0.0 0
M  V30 22 ? 5.1492 -2.5746 0.0 0 MASS=58
M  V30 23 C -6.1718 -2.5385 0.0 0
M  V30 24 C -6.1718 0.4451 0.0 0
M  V30 25 C -7.5072 -1.7565 0.0 0
M  V30 26 ? -6.2079 -4.0062 0.0 0 MASS=56
M  V30 27 C -7.5072 -0.2646 0.0 0
M  V30 28 ? -6.2079 1.985 0.0 0 MASS=53
M  V30 29 ? -8.8426 -2.4783 0.0 0 MASS=55
M  V30 30 ? -8.8426 0.5052 0.0 0 MASS=54
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 2 2 5
M  V30 5 1 2 6
M  V30 6 2 3 7
M  V30 7 1 3 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 7 12
M  V30 12 1 7 13
M  V30 13 2 8 14
M  V30 14 2 9 15
M  V30 15 1 9 16
M  V30 16 1 11 17
M  V30 17 1 12 18
M  V30 18 1 12 19
M  V30 19 1 13 20
M  V30 20 2 13 21
M  V30 21 1 15 22
M  V30 22 1 18 23
M  V30 23 1 20 24
M  V30 24 2 23 25
M  V30 25 1 23 26
M  V30 26 2 24 27
M  V30 27 1 24 28
M  V30 28 1 25 29
M  V30 29 1 27 30
M  V30 30 1 6 8
M  V30 31 1 11 15
M  V30 32 2 18 20
M  V30 33 1 25 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000737A1-20220106-C00010

>  <Row No>
543

$$$$
US20220000737A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.4309 -1.4124 0.0 0
M  V30 3 C -1.8313 -1.9989 0.0 0
M  V30 4 C 0.5266 -2.4776 0.0 0
M  V30 5 C -3.1599 -1.2208 0.0 0
M  V30 6 C -1.7116 -3.4472 0.0 0
M  V30 7 C -0.2393 -3.7345 0.0 0
M  V30 8 C 1.9869 -2.4417 0.0 0
M  V30 9 N -4.4885 -1.939 0.0 0
M  V30 10 C -3.1958 0.3112 0.0 0
M  V30 11 O -2.8008 -4.4646 0.0 0
M  V30 12 C 0.4787 -4.9913 0.0 0
M  V30 13 C 2.7051 -3.6985 0.0 0
M  V30 14 C -5.8172 -1.161 0.0 0
M  V30 15 C -4.5244 1.0772 0.0 0
M  V30 16 C 1.939 -4.9553 0.0 0
M  V30 17 C -5.8531 0.371 0.0 0
M  V30 18 C -7.1458 -1.8792 0.0 0
M  V30 19 C -7.1817 1.149 0.0 0
M  V30 20 C -8.4744 -1.1011 0.0 0
M  V30 21 ? -7.1817 -3.3395 0.0 0 MASS=63
M  V30 22 C -8.5103 0.4309 0.0 0
M  V30 23 ? -7.2176 2.6811 0.0 0 MASS=64
M  V30 24 ? -9.803 -1.8193 0.0 0 MASS=62
M  V30 25 ? -9.8389 1.2089 0.0 0 MASS=61
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 2 5 9
M  V30 9 1 5 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 2 8 13
M  V30 13 1 9 14
M  V30 14 2 10 15
M  V30 15 2 12 16
M  V30 16 1 14 17
M  V30 17 2 14 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 22 25
M  V30 25 1 6 7
M  V30 26 1 13 16
M  V30 27 1 15 17
M  V30 28 2 20 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000737A1-20220106-C00011

>  <Row No>
544

$$$$
US20220000737A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00035001.cdx

>  <name>
US20220000737A1-20220106-C00012

>  <Row No>
545

$$$$
US20220000737A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=12
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000737A1-20220106-C00013

>  <Row No>
546

$$$$
US20220000737A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=16
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000737A1-20220106-C00014

>  <Row No>
547

$$$$
US20220000737A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00038001.cdx

>  <name>
US20220000737A1-20220106-C00015

>  <Row No>
548

$$$$
US20220000737A1-20220106-C00016
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.7483 -1.1411 0.0 0
M  V30 3 N 0.6921 -1.085 0.0 0
M  V30 4 C -3.1428 -1.085 0.0 0
M  V30 5 C 2.0578 -1.0289 0.0 0
M  V30 6 C -4.5646 -1.0289 0.0 0
M  V30 7 N 4.3027 -0.9727 0.0 0 CHG=1
M  V30 8 O -3.9285 0.187 0.0 0
M  V30 9 N -6.0986 -0.9727 0.0 0
M  V30 10 A 5.818 -0.9353 0.0 0
M  V30 11 ? 4.2653 -2.0952 0.0 0 MASS=21
M  V30 12 ? 4.2653 0.2244 0.0 0 MASS=20
M  V30 13 C -8.4932 -0.9166 0.0 0
M  V30 14 C 6.9592 -0.8792 0.0 0
M  V30 15 N -9.9524 -0.8418 0.0 0 CHG=1
M  V30 16 C -11.1497 -0.7857 0.0 0
M  V30 17 ? -9.9898 -1.9642 0.0 0 MASS=19
M  V30 18 ? -10.0085 0.3554 0.0 0 MASS=18
M  V30 19 C -10.6259 -1.3469 0.0 0 CHG=-1
M  V30 20 C 3.2925 -2.6938 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 1 9 13
M  V30 13 1 10 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00039001.cdx

>  <name>
US20220000737A1-20220106-C00016

>  <Row No>
549

$$$$
US20220000737A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 5 4 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C -0.0403 1.3179 0.0 0 CFG=2
M  V30 3 C -1.7616 1.3582 0.0 0
M  V30 4 C 1.6003 1.3582 0.0 0
M  V30 5 C -3.0795 1.3985 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4 CFG=3
M  V30 4 1 3 5
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00040001.cdx

>  <name>
US20220000737A1-20220106-C00017

>  <Row No>
550

$$$$
US20220000737A1-20220106-C00018
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 7 6 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0405 1.3122 0.0 0
M  V30 3 N -1.7722 1.3528 0.0 0
M  V30 4 C -1.8128 2.6651 0.0 0 CFG=2
M  V30 5 C -3.5174 2.7057 0.0 0
M  V30 6 C -0.1894 2.7057 0.0 0
M  V30 7 C -4.8297 2.7463 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 4 1 4 5
M  V30 5 1 4 6 CFG=3
M  V30 6 1 5 7
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 4)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00041001.cdx

>  <name>
US20220000737A1-20220106-C00018

>  <Row No>
551

$$$$
US20220000737A1-20220106-C00019
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00042001.cdx

>  <name>
US20220000737A1-20220106-C00019

>  <Row No>
552

$$$$
US20220000737A1-20220106-C00020
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00043001.cdx

>  <name>
US20220000737A1-20220106-C00020

>  <Row No>
553

$$$$
US20220000737A1-20220106-C00021
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=9
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00044001.cdx

>  <name>
US20220000737A1-20220106-C00021

>  <Row No>
554

$$$$
US20220000737A1-20220106-C00022
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=10
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00046001.cdx

>  <name>
US20220000737A1-20220106-C00022

>  <Row No>
555

$$$$
US20220000737A1-20220106-C00023
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=16
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00047001.cdx

>  <name>
US20220000737A1-20220106-C00023

>  <Row No>
556

$$$$
US20220000737A1-20220106-C00024
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 72 79 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 1.5382 0.0 0
M  V30 3 C 1.2257 2.3073 0.0 0
M  V30 4 C -1.3699 2.3073 0.0 0
M  V30 5 C 2.4875 1.5862 0.0 0
M  V30 6 C 1.1897 3.8455 0.0 0
M  V30 7 C -1.406 3.8455 0.0 0
M  V30 8 C -2.7038 1.5862 0.0 0
M  V30 9 N 2.4515 0.1201 0.0 0
M  V30 10 C 3.7493 2.3553 0.0 0
M  V30 11 C -0.1442 4.6146 0.0 0
M  V30 12 C 2.4515 4.6146 0.0 0
M  V30 13 C -2.7399 4.6146 0.0 0
M  V30 14 C -4.0377 2.3553 0.0 0
M  V30 15 ? -2.7399 0.1201 0.0 0 MASS=25
M  V30 16 C 2.4154 -1.3459 0.0 0
M  V30 17 ? 1.1175 -0.6008 0.0 0 MASS=28
M  V30 18 C 3.7133 3.8935 0.0 0
M  V30 19 ? 5.0111 1.6343 0.0 0 MASS=27
M  V30 20 O -0.1802 6.1528 0.0 0
M  V30 21 C 2.4154 6.1528 0.0 0
M  V30 22 C -4.0738 3.8935 0.0 0
M  V30 23 ? -2.7759 6.1528 0.0 0 MASS=22
M  V30 24 ? -5.3716 1.6343 0.0 0 MASS=24
M  V30 25 C 3.6772 -2.0789 0.0 0
M  V30 26 C 1.0815 -2.0789 0.0 0
M  V30 27 ? 4.9751 4.6626 0.0 0 MASS=26
M  V30 28 ? -5.4077 4.6626 0.0 0 MASS=23
M  V30 29 C 4.939 -1.3098 0.0 0
M  V30 30 C 3.6412 -3.545 0.0 0
M  V30 31 C 1.0454 -3.545 0.0 0
M  V30 32 ? -0.2523 -1.3098 0.0 0 MASS=27
M  V30 33 O 4.903 0.2283 0.0 0
M  V30 34 C 6.2008 -2.0429 0.0 0
M  V30 35 C 4.903 -4.2661 0.0 0
M  V30 36 C 2.3073 -4.2661 0.0 0
M  V30 37 ? -0.2884 -4.2661 0.0 0 MASS=26
M  V30 38 C 6.1648 -3.509 0.0 0
M  V30 39 C 7.4626 -1.2738 0.0 0
M  V30 40 O 4.8669 -5.7322 0.0 0
M  V30 41 C 2.2712 -5.7322 0.0 0
M  V30 42 C 7.4266 -4.23 0.0 0
M  V30 43 C 8.7244 -2.0068 0.0 0
M  V30 44 ? 7.4266 0.2643 0.0 0 MASS=25
M  V30 45 C 8.6884 -3.4489 0.0 0
M  V30 46 ? 7.3905 -5.6961 0.0 0 MASS=22
M  V30 47 ? 9.9862 -1.2377 0.0 0 MASS=24
M  V30 48 ? 9.9502 -4.1699 0.0 0 MASS=23
M  V30 49 O -0.2884 10.1905 0.0 0
M  V30 50 C -0.3244 11.7287 0.0 0
M  V30 51 C 0.9373 12.4978 0.0 0
M  V30 52 C -1.6583 12.4978 0.0 0
M  V30 53 C 0.9012 14.036 0.0 0
M  V30 54 C 2.1991 11.7648 0.0 0
M  V30 55 C -1.6944 14.036 0.0 0
M  V30 56 C -2.9922 11.7648 0.0 0
M  V30 57 C -0.4326 14.8051 0.0 0
M  V30 58 C 2.163 14.8051 0.0 0
M  V30 59 C 3.4609 12.5339 0.0 0
M  V30 60 C 2.163 10.2987 0.0 0
M  V30 61 C -3.0283 14.8051 0.0 0
M  V30 62 C -4.3261 12.5339 0.0 0
M  V30 63 ? -3.0283 10.2987 0.0 0 MASS=25
M  V30 64 O -0.4686 16.3433 0.0 0
M  V30 65 C 3.4249 14.0841 0.0 0
M  V30 66 C 2.127 16.3433 0.0 0
M  V30 67 ? 4.7227 11.8008 0.0 0 MASS=27
M  V30 68 C -4.3622 14.0841 0.0 0
M  V30 69 ? -3.0643 16.3433 0.0 0 MASS=22
M  V30 70 ? -5.6601 11.8008 0.0 0 MASS=24
M  V30 71 ? 4.6867 14.8532 0.0 0 MASS=26
M  V30 72 ? -5.6961 14.8532 0.0 0 MASS=23
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 1 6 11
M  V30 11 2 6 12
M  V30 12 1 7 13
M  V30 13 2 8 14
M  V30 14 1 8 15
M  V30 15 1 9 16
M  V30 16 1 9 17
M  V30 17 2 10 18
M  V30 18 1 10 19
M  V30 19 2 11 20
M  V30 20 1 12 21
M  V30 21 2 13 22
M  V30 22 1 13 23
M  V30 23 1 14 24
M  V30 24 2 16 25
M  V30 25 1 16 26
M  V30 26 1 18 27
M  V30 27 1 22 28
M  V30 28 1 25 29
M  V30 29 1 25 30
M  V30 30 2 26 31
M  V30 31 1 26 32
M  V30 32 2 29 33
M  V30 33 1 29 34
M  V30 34 1 30 35
M  V30 35 2 30 36
M  V30 36 1 31 37
M  V30 37 2 34 38
M  V30 38 1 34 39
M  V30 39 2 35 40
M  V30 40 1 36 41
M  V30 41 1 38 42
M  V30 42 2 39 43
M  V30 43 1 39 44
M  V30 44 2 42 45
M  V30 45 1 42 46
M  V30 46 1 43 47
M  V30 47 1 45 48
M  V30 48 2 49 50
M  V30 49 1 50 51
M  V30 50 1 50 52
M  V30 51 2 51 53
M  V30 52 1 51 54
M  V30 53 2 52 55
M  V30 54 1 52 56
M  V30 55 1 53 57
M  V30 56 1 53 58
M  V30 57 2 54 59
M  V30 58 1 54 60
M  V30 59 1 55 61
M  V30 60 2 56 62
M  V30 61 1 56 63
M  V30 62 2 57 64
M  V30 63 2 58 65
M  V30 64 1 58 66
M  V30 65 1 59 67
M  V30 66 2 61 68
M  V30 67 1 61 69
M  V30 68 1 62 70
M  V30 69 1 65 71
M  V30 70 1 68 72
M  V30 71 1 7 11
M  V30 72 1 12 18
M  V30 73 1 14 22
M  V30 74 1 31 36
M  V30 75 1 35 38
M  V30 76 1 43 45
M  V30 77 1 55 57
M  V30 78 1 59 65
M  V30 79 1 62 68
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00048001.cdx

>  <name>
US20220000737A1-20220106-C00024

>  <Row No>
557

$$$$
US20220000737A1-20220106-C00025
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 56 53 0 0 0
M  V30 BEGIN ATOM
M  V30 1 W 0.0 0.0 0.0 0 VAL=2
M  V30 2 C 1.3214 0.0966 0.0 0
M  V30 3 C -1.0958 -0.9024 0.0 0
M  V30 4 C 3.4163 0.1933 0.0 0
M  V30 5 S 0.0 11.6027 0.0 0
M  V30 6 O -1.5148 11.6994 0.0 0
M  V30 7 O 1.3214 11.6994 0.0 0
M  V30 8 O -0.0966 13.1175 0.0 0 CHG=-1
M  V30 9 C -0.0966 10.2813 0.0 0
M  V30 10 O 5.1567 13.1497 0.0 0
M  V30 11 N 4.351 12.0217 0.0 0 CHG=1
M  V30 12 O 2.8362 12.1184 0.0 0 CHG=-1
M  V30 13 C 4.9633 10.8936 0.0 0
M  V30 14 C 4.1576 9.7656 0.0 0
M  V30 15 C 6.2848 10.9903 0.0 0
M  V30 16 N 2.6428 9.8623 0.0 0
M  V30 17 C 4.77 8.6375 0.0 0
M  V30 18 C 6.8971 9.8623 0.0 0
M  V30 19 C 1.128 9.959 0.0 0
M  V30 20 C 2.5461 8.5409 0.0 0
M  V30 21 C 6.0914 8.7342 0.0 0
M  V30 22 C 8.2186 9.959 0.0 0
M  V30 23 C 0.3222 8.8309 0.0 0
M  V30 24 C 0.3222 11.2804 0.0 0
M  V30 25 C -1.1925 8.9276 0.0 0
M  V30 26 C -1.1925 11.3771 0.0 0
M  V30 27 C -1.9982 10.249 0.0 0
M  V30 28 N -3.513 10.3457 0.0 0
M  V30 29 C -5.0278 10.4424 0.0 0
M  V30 30 C -3.6097 9.0243 0.0 0
M  V30 31 C -5.8335 9.3144 0.0 0
M  V30 32 C -5.8335 11.7638 0.0 0
M  V30 33 C -7.3483 9.4111 0.0 0
M  V30 34 C -7.3483 11.8605 0.0 0
M  V30 35 C -8.1541 10.7325 0.0 0
M  V30 36 O -3.3519 -4.641 0.0 0
M  V30 37 N -2.2238 -3.8353 0.0 0 CHG=1
M  V30 38 O -1.0958 -4.4477 0.0 0 CHG=-1
M  V30 39 C -2.3205 -2.3205 0.0 0
M  V30 40 C -3.6419 -1.5148 0.0 0
M  V30 41 C -1.1925 -1.5148 0.0 0
M  V30 42 C -3.7386 0.0 0.0 0
M  V30 43 C -4.9633 -2.1271 0.0 0
M  V30 44 C -1.2891 0.0 0.0 0
M  V30 45 C -2.6106 0.8057 0.0 0
M  V30 46 C -5.06 0.8057 0.0 0
M  V30 47 C -6.2848 -1.3214 0.0 0
M  V30 48 C -6.3815 0.1933 0.0 0
M  V30 49 C -2.8362 -1.0313 0.0 0
M  V30 50 C -6.9616 -0.9346 0.0 0
M  V30 51 C -6.4459 9.7978 0.0 0
M  V30 52 C -7.7673 10.6036 0.0 0
M  V30 53 C 5.6724 8.5086 0.0 0
M  V30 54 ? 5.5757 7.1872 0.0 0 MASS=32
M  V30 55 C 0.0 8.5086 0.0 0
M  V30 56 ? -0.0966 7.1872 0.0 0 MASS=31
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 2 5 6
M  V30 5 2 5 7
M  V30 6 1 5 8
M  V30 7 1 5 9
M  V30 8 2 10 11
M  V30 9 1 11 12
M  V30 10 1 11 13
M  V30 11 2 13 14
M  V30 12 1 13 15
M  V30 13 1 14 16
M  V30 14 1 14 17
M  V30 15 2 15 18
M  V30 16 1 16 19
M  V30 17 1 16 20
M  V30 18 2 17 21
M  V30 19 1 18 22
M  V30 20 2 19 23
M  V30 21 1 19 24
M  V30 22 1 23 25
M  V30 23 2 24 26
M  V30 24 2 25 27
M  V30 25 1 27 28
M  V30 26 1 28 29
M  V30 27 1 28 30
M  V30 28 2 29 31
M  V30 29 1 29 32
M  V30 30 1 31 33
M  V30 31 2 32 34
M  V30 32 2 33 35
M  V30 33 2 36 37
M  V30 34 1 37 38
M  V30 35 1 37 39
M  V30 36 2 39 40
M  V30 37 1 39 41
M  V30 38 1 40 42
M  V30 39 1 40 43
M  V30 40 2 41 44
M  V30 41 2 42 45
M  V30 42 1 42 46
M  V30 43 1 43 47
M  V30 44 1 46 48
M  V30 45 1 49 50
M  V30 46 1 51 52
M  V30 47 1 53 54
M  V30 48 1 55 56
M  V30 49 1 18 21
M  V30 50 1 26 27
M  V30 51 1 34 35
M  V30 52 1 44 45
M  V30 53 1 47 48
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00050001.cdx

>  <name>
US20220000737A1-20220106-C00025

>  <Row No>
558

$$$$
US20220000737A1-20220106-C00026
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -0.0348 -1.4657 0.0 0
M  V30 3 C -1.3377 0.791 0.0 0
M  V30 4 C 1.2679 0.791 0.0 0
M  V30 5 C -1.3726 -2.1636 0.0 0
M  V30 6 C 1.233 -2.1636 0.0 0
M  V30 7 C -2.6754 0.093 0.0 0
M  V30 8 C -2.7103 -1.3726 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 5 8
M  V30 8 1 7 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00051001.cdx

>  <name>
US20220000737A1-20220106-C00026

>  <Row No>
559

$$$$
US20220000737A1-20220106-C00027
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 44 35 0 0 0
M  V30 BEGIN ATOM
M  V30 1 I 0.0 0.0 0.0 0
M  V30 2 N 4.9775 6.1262 0.0 0 CHG=1
M  V30 3 C 3.6494 5.3963 0.0 0
M  V30 4 ? 6.2339 5.3963 0.0 0 MASS=36
M  V30 5 ? 4.9416 7.6578 0.0 0 MASS=35
M  V30 6 C 2.3212 6.1741 0.0 0
M  V30 7 C 3.6135 3.9365 0.0 0
M  V30 8 C 0.9931 5.4442 0.0 0
M  V30 9 C 2.2853 3.2186 0.0 0
M  V30 10 C 0.9572 3.9844 0.0 0
M  V30 11 C -0.3709 3.2665 0.0 0
M  V30 12 C -1.699 4.0442 0.0 0
M  V30 13 C -0.4068 1.8067 0.0 0
M  V30 14 C -3.0272 3.3263 0.0 0
M  V30 15 C -1.7349 5.5758 0.0 0
M  V30 16 C -1.7349 1.0888 0.0 0
M  V30 17 C 0.8495 1.0888 0.0 0
M  V30 18 C -4.3553 4.1041 0.0 0
M  V30 19 C -3.0631 6.3535 0.0 0
M  V30 20 C -1.7708 -0.3709 0.0 0
M  V30 21 C 0.8136 -0.3709 0.0 0
M  V30 22 C -4.3912 5.6356 0.0 0
M  V30 23 C -0.5145 -1.0888 0.0 0
M  V30 24 N -5.7194 6.4134 0.0 0
M  V30 25 ? -7.0475 5.6954 0.0 0 MASS=34
M  V30 26 ? -5.7553 7.9449 0.0 0 MASS=33
M  V30 27 C 0.67 0.2871 0.0 0
M  V30 28 ? 2.1298 0.323 0.0 0 MASS=44
M  V30 29 C 0.1914 -0.5743 0.0 0
M  V30 30 ? 0.9213 -1.8306 0.0 0 MASS=43
M  V30 31 C -0.8615 -0.4786 0.0 0
M  V30 32 ? -1.6392 -1.7349 0.0 0 MASS=42
M  V30 33 C -1.2443 0.2871 0.0 0
M  V30 34 ? -2.7759 0.323 0.0 0 MASS=41
M  V30 35 C 2.7759 4.0203 0.0 0
M  V30 36 ? 3.4938 2.7639 0.0 0 MASS=40
M  V30 37 C 1.8187 5.7433 0.0 0
M  V30 38 ? 1.0529 7.0715 0.0 0 MASS=39
M  V30 39 C -3.3502 4.116 0.0 0
M  V30 40 ? -4.128 2.8597 0.0 0 MASS=38
M  V30 41 C -2.5845 5.7433 0.0 0
M  V30 42 ? -1.8546 7.0715 0.0 0 MASS=37
M  V30 43 C -2.8716 4.8818 0.0 0
M  V30 44 H 2.2973 4.8818 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 2 3
M  V30 2 1 2 4
M  V30 3 1 2 5
M  V30 4 1 3 6
M  V30 5 1 3 7
M  V30 6 2 6 8
M  V30 7 2 7 9
M  V30 8 1 8 10
M  V30 9 2 10 11
M  V30 10 1 11 12
M  V30 11 1 11 13
M  V30 12 2 12 14
M  V30 13 1 12 15
M  V30 14 2 13 16
M  V30 15 1 13 17
M  V30 16 1 14 18
M  V30 17 2 15 19
M  V30 18 1 16 20
M  V30 19 2 17 21
M  V30 20 2 18 22
M  V30 21 2 20 23
M  V30 22 1 22 24
M  V30 23 1 24 25
M  V30 24 1 24 26
M  V30 25 1 27 28
M  V30 26 1 29 30
M  V30 27 1 31 32
M  V30 28 1 33 34
M  V30 29 1 35 36
M  V30 30 1 37 38
M  V30 31 1 39 40
M  V30 32 1 41 42
M  V30 33 1 9 10
M  V30 34 1 19 22
M  V30 35 1 21 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00052001.cdx

>  <name>
US20220000737A1-20220106-C00027

>  <Row No>
560

$$$$
US20220000737A1-20220106-C00028
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 34 36 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -0.0362 -1.4736 0.0 0
M  V30 3 C 1.2683 0.7851 0.0 0
M  V30 4 C -1.3166 0.773 0.0 0
M  V30 5 C 1.232 -2.1984 0.0 0
M  V30 6 C -1.377 -2.1984 0.0 0
M  V30 7 C 1.2562 2.2829 0.0 0
M  V30 8 C 2.5366 0.0603 0.0 0
M  V30 9 C -1.3287 2.2829 0.0 0
M  V30 10 C -2.6332 0.0362 0.0 0
M  V30 11 C 1.1958 -3.672 0.0 0
M  V30 12 C 2.6574 -1.7635 0.0 0
M  V30 13 C -1.4132 -3.672 0.0 0
M  V30 14 ? -2.7178 -1.4132 0.0 0 MASS=49
M  V30 15 C 2.5245 3.056 0.0 0
M  V30 16 C -0.0603 3.056 0.0 0
M  V30 17 C 3.8049 0.8455 0.0 0
M  V30 18 C -2.6453 3.056 0.0 0
M  V30 19 C -3.9498 0.8093 0.0 0
M  V30 20 C -0.1449 -4.4089 0.0 0
M  V30 21 ? 2.4641 -4.4089 0.0 0 MASS=52
M  V30 22 C 3.0198 -0.2657 0.0 0
M  V30 23 C 3.6841 -2.7902 0.0 0
M  V30 24 ? -2.754 -4.4089 0.0 0 MASS=50
M  V30 25 C 3.7928 2.3192 0.0 0
M  V30 26 ? 2.4883 4.6021 0.0 0 MASS=47
M  V30 27 ? 5.0732 0.1207 0.0 0 MASS=48
M  V30 28 C -3.9619 2.3192 0.0 0
M  V30 29 ? -2.6815 4.6021 0.0 0 MASS=45
M  V30 30 ? -5.2906 0.0845 0.0 0 MASS=46
M  V30 31 ? -0.1811 -5.8825 0.0 0 MASS=51
M  V30 32 C 5.0611 3.0922 0.0 0
M  V30 33 ? -5.2786 3.0922 0.0 0
M  V30 34 C 5.2182 -2.8023 0.0 0 CHG=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 2 2 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 3 8
M  V30 8 2 4 9
M  V30 9 1 4 10
M  V30 10 1 5 11
M  V30 11 1 5 12
M  V30 12 2 6 13
M  V30 13 1 6 14
M  V30 14 2 7 15
M  V30 15 1 7 16
M  V30 16 2 8 17
M  V30 17 1 9 18
M  V30 18 2 10 19
M  V30 19 2 11 20
M  V30 20 1 11 21
M  V30 21 2 12 22
M  V30 22 1 12 23
M  V30 23 1 13 24
M  V30 24 1 15 25
M  V30 25 1 15 26
M  V30 26 1 17 27
M  V30 27 2 18 28
M  V30 28 1 18 29
M  V30 29 1 19 30
M  V30 30 1 20 31
M  V30 31 2 25 32
M  V30 32 1 28 33
M  V30 33 1 9 16
M  V30 34 1 13 20
M  V30 35 1 17 25
M  V30 36 1 19 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00053001.cdx

>  <name>
US20220000737A1-20220106-C00028

>  <Row No>
561

$$$$
US20220000737A1-20220106-C00029
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 33 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C 1.3948 -0.4328 0.0 0
M  V30 3 C -0.9138 -1.1784 0.0 0
M  V30 4 C -0.4328 1.491 0.0 0
M  V30 5 C 2.6574 0.3366 0.0 0
M  V30 6 C 1.3587 -1.8998 0.0 0
M  V30 7 C -2.453 -1.1423 0.0 0
M  V30 8 C -0.0721 -2.3568 0.0 0
M  V30 9 C 3.92 -0.3847 0.0 0
M  V30 10 ? 2.6213 1.8758 0.0 0 MASS=60
M  V30 11 C 2.6213 -2.6213 0.0 0
M  V30 12 N -3.3668 -2.3207 0.0 0
M  V30 13 C -3.3668 0.1082 0.0 0
M  V30 14 C -0.505 -3.7757 0.0 0
M  V30 15 C 3.8839 -1.8517 0.0 0
M  V30 16 ? 5.1825 0.3847 0.0 0 MASS=59
M  V30 17 ? 2.5852 -4.0883 0.0 0 MASS=57
M  V30 18 C -4.8338 -1.8157 0.0 0
M  V30 19 C -3.0061 -3.7396 0.0 0
M  V30 20 C -4.8338 -0.3246 0.0 0
M  V30 21 C -3.0061 1.5992 0.0 0
M  V30 22 ? 5.1465 -2.5732 0.0 0 MASS=58
M  V30 23 C -6.1685 -2.5371 0.0 0
M  V30 24 C -6.1685 0.4449 0.0 0
M  V30 25 C -7.5033 -1.7676 0.0 0
M  V30 26 ? -6.2046 -4.0041 0.0 0 MASS=56
M  V30 27 C -7.5033 -0.2765 0.0 0
M  V30 28 ? -6.2046 1.984 0.0 0 MASS=53
M  V30 29 ? -8.838 -2.489 0.0 0 MASS=55
M  V30 30 ? -8.838 0.493 0.0 0 MASS=54
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 2 2 5
M  V30 5 1 2 6
M  V30 6 2 3 7
M  V30 7 1 3 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 7 12
M  V30 12 1 7 13
M  V30 13 2 8 14
M  V30 14 2 9 15
M  V30 15 1 9 16
M  V30 16 1 11 17
M  V30 17 1 12 18
M  V30 18 1 12 19
M  V30 19 1 13 20
M  V30 20 2 13 21
M  V30 21 1 15 22
M  V30 22 1 18 23
M  V30 23 1 20 24
M  V30 24 2 23 25
M  V30 25 1 23 26
M  V30 26 2 24 27
M  V30 27 1 24 28
M  V30 28 1 25 29
M  V30 29 1 27 30
M  V30 30 1 6 8
M  V30 31 1 11 15
M  V30 32 2 18 20
M  V30 33 1 25 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00054001.cdx

>  <name>
US20220000737A1-20220106-C00029

>  <Row No>
562

$$$$
US20220000737A1-20220106-C00030
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.4309 -1.4124 0.0 0
M  V30 3 C -1.8313 -1.9989 0.0 0
M  V30 4 C 0.5266 -2.4776 0.0 0
M  V30 5 C -3.1599 -1.2208 0.0 0
M  V30 6 C -1.7116 -3.4472 0.0 0
M  V30 7 C -0.2393 -3.7345 0.0 0
M  V30 8 C 1.9869 -2.4417 0.0 0
M  V30 9 N -4.4885 -1.939 0.0 0
M  V30 10 C -3.1958 0.3112 0.0 0
M  V30 11 O -2.8008 -4.4646 0.0 0
M  V30 12 C 0.4787 -4.9913 0.0 0
M  V30 13 C 2.7051 -3.6985 0.0 0
M  V30 14 C -5.8172 -1.161 0.0 0
M  V30 15 C -4.5244 1.0772 0.0 0
M  V30 16 C 1.939 -4.9553 0.0 0
M  V30 17 C -5.8531 0.371 0.0 0
M  V30 18 C -7.1458 -1.8792 0.0 0
M  V30 19 C -7.1817 1.149 0.0 0
M  V30 20 C -8.4744 -1.1011 0.0 0
M  V30 21 ? -7.1817 -3.3395 0.0 0 MASS=63
M  V30 22 C -8.5103 0.4309 0.0 0
M  V30 23 ? -7.2176 2.6811 0.0 0 MASS=64
M  V30 24 ? -9.803 -1.8193 0.0 0 MASS=62
M  V30 25 ? -9.8389 1.2089 0.0 0 MASS=61
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 2 5 9
M  V30 9 1 5 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 2 8 13
M  V30 13 1 9 14
M  V30 14 2 10 15
M  V30 15 2 12 16
M  V30 16 1 14 17
M  V30 17 2 14 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 22 25
M  V30 25 1 6 7
M  V30 26 1 13 16
M  V30 27 1 15 17
M  V30 28 2 20 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00055001.cdx

>  <name>
US20220000737A1-20220106-C00030

>  <Row No>
563

$$$$
US20220000742A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 66 73 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0584 1.5186 0.0 0
M  V30 3 O 1.1487 2.3364 0.0 0
M  V30 4 C -1.3823 2.3364 0.0 0
M  V30 5 C 2.3753 1.6355 0.0 0
M  V30 6 C -2.7063 1.6355 0.0 0
M  V30 7 C -1.4407 3.8551 0.0 0
M  V30 8 C 2.3169 0.2336 0.0 0
M  V30 9 C 3.6019 2.4532 0.0 0
M  V30 10 C -4.0303 2.4532 0.0 0
M  V30 11 C -2.7647 4.6728 0.0 0
M  V30 12 O 3.5435 -0.4672 0.0 0
M  V30 13 C 0.0778 -1.0124 0.0 0
M  V30 14 C 4.8286 1.7523 0.0 0
M  V30 15 O -5.3543 1.7523 0.0 0
M  V30 16 C -4.0887 3.9719 0.0 0
M  V30 17 O -2.8231 6.1915 0.0 0
M  V30 18 C 4.7702 0.3504 0.0 0
M  V30 19 C 0.0194 -2.4143 0.0 0
M  V30 20 C -1.246 -0.1947 0.0 0
M  V30 21 C 6.0357 2.57 0.0 0
M  V30 22 O -5.4127 4.7896 0.0 0
M  V30 23 C 5.9773 -0.3504 0.0 0
M  V30 24 C -1.3045 -3.1152 0.0 0
M  V30 25 C 1.246 -3.1152 0.0 0
M  V30 26 C -2.57 -0.8956 0.0 0
M  V30 27 O 5.9773 4.0887 0.0 0
M  V30 28 C 7.2624 1.8691 0.0 0
M  V30 29 C 7.2039 0.4672 0.0 0
M  V30 30 O -1.3629 -4.517 0.0 0
M  V30 31 C -2.6284 -2.2974 0.0 0
M  V30 32 C 2.4532 -2.2974 0.0 0
M  V30 33 C 1.1876 -4.517 0.0 0
M  V30 34 O -3.894 -0.0778 0.0 0
M  V30 35 O 8.4306 -0.2336 0.0 0
M  V30 36 O -3.9524 -2.9984 0.0 0
M  V30 37 O 2.3948 -0.7788 0.0 0
M  V30 38 C 3.6798 -2.9984 0.0 0
M  V30 39 C 2.4143 -5.218 0.0 0
M  V30 40 C -1.3045 -5.8605 0.0 0
M  V30 41 O 4.9065 -2.1806 0.0 0
M  V30 42 C 3.6214 -4.4002 0.0 0
M  V30 43 O -2.6284 -5.0427 0.0 0
M  V30 44 C -1.3629 -7.2624 0.0 0
M  V30 45 O 4.848 -5.1012 0.0 0
M  V30 46 C -3.9524 -5.7437 0.0 0
M  V30 47 O -0.1557 -7.9633 0.0 0
M  V30 48 C -2.6868 -7.9633 0.0 0
M  V30 49 C -4.0108 -7.1455 0.0 0
M  V30 50 C -5.2764 -4.9259 0.0 0
M  V30 51 C 1.0708 -7.1455 0.0 0
M  V30 52 C -5.3348 -7.8465 0.0 0
M  V30 53 C -6.6004 -5.6269 0.0 0
M  V30 54 O 1.0124 -5.6269 0.0 0
M  V30 55 C 2.278 -7.8465 0.0 0
M  V30 56 O -5.3932 -9.2483 0.0 0
M  V30 57 C -6.6588 -7.0287 0.0 0
M  V30 58 O -7.9243 -4.8091 0.0 0
M  V30 59 C 3.5046 -7.0287 0.0 0
M  V30 60 C 2.2196 -9.2483 0.0 0
M  V30 61 C 4.7312 -7.7296 0.0 0
M  V30 62 C 3.4462 -9.9493 0.0 0
M  V30 63 O 5.9578 -6.9119 0.0 0
M  V30 64 C 4.6728 -9.1315 0.0 0
M  V30 65 O 3.3878 -11.3511 0.0 0
M  V30 66 O 5.8994 -9.8324 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 2 7 11
M  V30 11 1 8 12
M  V30 12 1 8 13
M  V30 13 1 9 14
M  V30 14 1 10 15
M  V30 15 2 10 16
M  V30 16 1 11 17
M  V30 17 1 12 18
M  V30 18 2 13 19
M  V30 19 1 13 20
M  V30 20 1 14 21
M  V30 21 1 16 22
M  V30 22 1 18 23
M  V30 23 1 19 24
M  V30 24 1 19 25
M  V30 25 2 20 26
M  V30 26 1 21 27
M  V30 27 2 21 28
M  V30 28 2 23 29
M  V30 29 1 24 30
M  V30 30 2 24 31
M  V30 31 2 25 32
M  V30 32 1 25 33
M  V30 33 1 26 34
M  V30 34 1 29 35
M  V30 35 1 31 36
M  V30 36 1 32 37
M  V30 37 1 32 38
M  V30 38 2 33 39
M  V30 39 1 33 40
M  V30 40 1 38 41
M  V30 41 2 38 42
M  V30 42 1 40 43
M  V30 43 1 40 44
M  V30 44 1 42 45
M  V30 45 1 43 46
M  V30 46 1 44 47
M  V30 47 1 44 48
M  V30 48 2 46 49
M  V30 49 1 46 50
M  V30 50 1 47 51
M  V30 51 1 49 52
M  V30 52 2 50 53
M  V30 53 2 51 54
M  V30 54 1 51 55
M  V30 55 1 52 56
M  V30 56 2 52 57
M  V30 57 1 53 58
M  V30 58 2 55 59
M  V30 59 1 55 60
M  V30 60 1 59 61
M  V30 61 2 60 62
M  V30 62 1 61 63
M  V30 63 2 61 64
M  V30 64 1 62 65
M  V30 65 1 64 66
M  V30 66 1 11 16
M  V30 67 2 14 18
M  V30 68 1 26 31
M  V30 69 1 28 29
M  V30 70 1 39 42
M  V30 71 1 48 49
M  V30 72 1 53 57
M  V30 73 1 62 64
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000742A1-20220106-C00001

>  <Row No>
564

$$$$
US20220000742A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 33 36 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2617 0.769 0.0 0
M  V30 3 O 1.2256 2.3071 0.0 0
M  V30 4 C 2.5234 0.048 0.0 0
M  V30 5 C -0.1081 3.0762 0.0 0 CFG=1
M  V30 6 C 2.4874 -1.4179 0.0 0
M  V30 7 C 3.7852 0.8291 0.0 0
M  V30 8 C -0.1441 4.6143 0.0 0 CFG=2
M  V30 9 C -1.4419 2.3552 0.0 0
M  V30 10 C 3.7491 -2.1389 0.0 0
M  V30 11 C 5.0469 0.1081 0.0 0
M  V30 12 O -1.478 5.3954 0.0 0
M  V30 13 C 1.1175 5.3954 0.0 0
M  V30 14 C -2.7758 3.1243 0.0 0
M  V30 15 O 3.7131 -3.6049 0.0 0
M  V30 16 C 5.0109 -1.3578 0.0 0
M  V30 17 O 6.3087 0.8772 0.0 0
M  V30 18 C -2.8118 4.6744 0.0 0
M  V30 19 C 2.3792 4.6744 0.0 0
M  V30 20 C 1.0814 6.9335 0.0 0
M  V30 21 C -4.1096 2.4033 0.0 0
M  V30 22 O 6.2726 -2.0788 0.0 0
M  V30 23 C -4.1457 5.4555 0.0 0
M  V30 24 C 3.641 5.4555 0.0 0
M  V30 25 C 2.3432 7.7026 0.0 0
M  V30 26 O -4.1457 0.9372 0.0 0
M  V30 27 C -5.4435 3.1843 0.0 0
M  V30 28 C -5.4795 4.7345 0.0 0
M  V30 29 O 4.9027 4.7345 0.0 0
M  V30 30 C 3.6049 6.9936 0.0 0
M  V30 31 O 2.3071 9.2407 0.0 0
M  V30 32 O -6.8134 5.5035 0.0 0
M  V30 33 O 4.8667 7.7747 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=3
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 2 7 11
M  V30 11 1 8 12
M  V30 12 1 8 13 CFG=3
M  V30 13 1 9 14
M  V30 14 1 10 15
M  V30 15 2 10 16
M  V30 16 1 11 17
M  V30 17 1 12 18
M  V30 18 2 13 19
M  V30 19 1 13 20
M  V30 20 1 14 21
M  V30 21 1 16 22
M  V30 22 1 18 23
M  V30 23 1 19 24
M  V30 24 2 20 25
M  V30 25 1 21 26
M  V30 26 2 21 27
M  V30 27 2 23 28
M  V30 28 1 24 29
M  V30 29 2 24 30
M  V30 30 1 25 31
M  V30 31 1 28 32
M  V30 32 1 30 33
M  V30 33 1 11 16
M  V30 34 2 14 18
M  V30 35 1 25 30
M  V30 36 1 27 28
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 5 8)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000742A1-20220106-C00002

>  <Row No>
565

$$$$
US20220000742A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 66 73 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0553 1.5301 0.0 0
M  V30 3 O 1.1614 2.3412 0.0 0
M  V30 4 C -1.3826 2.3412 0.0 0
M  V30 5 C 2.3596 1.6407 0.0 0
M  V30 6 C -2.7099 1.6407 0.0 0
M  V30 7 C -1.4379 3.8713 0.0 0
M  V30 8 C 2.3043 0.2212 0.0 0
M  V30 9 C 3.5764 2.4334 0.0 0
M  V30 10 C -4.0372 2.4518 0.0 0
M  V30 11 C -2.7652 4.6825 0.0 0
M  V30 12 O 3.521 -0.4608 0.0 0
M  V30 13 C -0.0553 -1.0507 0.0 0
M  V30 14 C 4.7746 1.7513 0.0 0
M  V30 15 O -5.3646 1.7513 0.0 0
M  V30 16 C -4.0925 3.9819 0.0 0
M  V30 17 O -2.8205 6.2126 0.0 0
M  V30 18 C 4.7193 0.3318 0.0 0
M  V30 19 C -0.1106 -2.4702 0.0 0
M  V30 20 C -1.3826 -0.2396 0.0 0
M  V30 21 C 5.9913 2.5624 0.0 0
M  V30 22 O -5.4199 4.7931 0.0 0
M  V30 23 C 5.936 -0.3687 0.0 0
M  V30 24 C -1.4379 -3.1708 0.0 0
M  V30 25 C 1.1061 -3.1708 0.0 0
M  V30 26 C -2.7099 -0.9401 0.0 0
M  V30 27 O 5.936 4.0925 0.0 0
M  V30 28 C 7.2081 1.8619 0.0 0
M  V30 29 C 7.1528 0.4424 0.0 0
M  V30 30 O -1.4932 -4.5903 0.0 0
M  V30 31 C -2.7652 -2.3596 0.0 0
M  V30 32 C 2.3228 -2.3596 0.0 0
M  V30 33 C 1.0507 -4.5903 0.0 0
M  V30 34 O -4.0372 -0.129 0.0 0
M  V30 35 O 8.3695 -0.258 0.0 0
M  V30 36 O -4.0925 -3.0602 0.0 0
M  V30 37 O 2.2675 -0.8295 0.0 0
M  V30 38 C 3.5395 -3.0602 0.0 0
M  V30 39 C 2.2675 -5.2908 0.0 0
M  V30 40 C -1.3088 -5.8623 0.0 0
M  V30 41 O 4.7562 -2.249 0.0 0
M  V30 42 C 3.4842 -4.4797 0.0 0
M  V30 43 O -2.6362 -5.0696 0.0 0
M  V30 44 C -1.3641 -7.2818 0.0 0
M  V30 45 O 4.7009 -5.1802 0.0 0
M  V30 46 C -3.9451 -5.7517 0.0 0
M  V30 47 O -0.1659 -7.9823 0.0 0
M  V30 48 C -2.6915 -7.9639 0.0 0
M  V30 49 C -4.0004 -7.1712 0.0 0
M  V30 50 C -5.2724 -4.9405 0.0 0
M  V30 51 C 1.0507 -7.1712 0.0 0
M  V30 52 C -5.3277 -7.8717 0.0 0
M  V30 53 C -6.5997 -5.6411 0.0 0
M  V30 54 O 0.9954 -5.6411 0.0 0
M  V30 55 C 2.2675 -7.8717 0.0 0
M  V30 56 O -5.383 -9.2912 0.0 0
M  V30 57 C -6.655 -7.0606 0.0 0
M  V30 58 O -7.927 -4.8299 0.0 0
M  V30 59 C 2.2122 -9.2912 0.0 0
M  V30 60 C 3.4842 -7.0606 0.0 0
M  V30 61 C 3.4289 -9.9917 0.0 0
M  V30 62 C 4.7009 -7.7611 0.0 0
M  V30 63 O 3.3736 -11.4112 0.0 0
M  V30 64 C 4.6456 -9.1806 0.0 0
M  V30 65 O 5.9176 -6.95 0.0 0
M  V30 66 O 5.8623 -9.8811 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 2 7 11
M  V30 11 1 8 12
M  V30 12 1 8 13
M  V30 13 1 9 14
M  V30 14 1 10 15
M  V30 15 2 10 16
M  V30 16 1 11 17
M  V30 17 1 12 18
M  V30 18 2 13 19
M  V30 19 1 13 20
M  V30 20 1 14 21
M  V30 21 1 16 22
M  V30 22 1 18 23
M  V30 23 1 19 24
M  V30 24 1 19 25
M  V30 25 2 20 26
M  V30 26 1 21 27
M  V30 27 2 21 28
M  V30 28 2 23 29
M  V30 29 1 24 30
M  V30 30 2 24 31
M  V30 31 2 25 32
M  V30 32 1 25 33
M  V30 33 1 26 34
M  V30 34 1 29 35
M  V30 35 1 31 36
M  V30 36 1 32 37
M  V30 37 1 32 38
M  V30 38 2 33 39
M  V30 39 1 33 40
M  V30 40 1 38 41
M  V30 41 2 38 42
M  V30 42 1 40 43
M  V30 43 1 40 44
M  V30 44 1 42 45
M  V30 45 1 43 46
M  V30 46 1 44 47
M  V30 47 1 44 48
M  V30 48 2 46 49
M  V30 49 1 46 50
M  V30 50 1 47 51
M  V30 51 1 49 52
M  V30 52 2 50 53
M  V30 53 2 51 54
M  V30 54 1 51 55
M  V30 55 1 52 56
M  V30 56 2 52 57
M  V30 57 1 53 58
M  V30 58 2 55 59
M  V30 59 1 55 60
M  V30 60 1 59 61
M  V30 61 2 60 62
M  V30 62 1 61 63
M  V30 63 2 61 64
M  V30 64 1 62 65
M  V30 65 1 64 66
M  V30 66 1 11 16
M  V30 67 2 14 18
M  V30 68 1 26 31
M  V30 69 1 28 29
M  V30 70 1 39 42
M  V30 71 1 48 49
M  V30 72 1 53 57
M  V30 73 1 62 64
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000742A1-20220106-C00003

>  <Row No>
566

$$$$
US20220000742A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 66 73 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0523 -1.4121 0.0 0
M  V30 3 O -1.3772 -2.0745 0.0 0
M  V30 4 C 1.168 -2.0745 0.0 0
M  V30 5 C -2.6847 -1.3075 0.0 0
M  V30 6 C 1.1157 -3.4867 0.0 0
M  V30 7 C 2.3883 -1.3075 0.0 0
M  V30 8 C -2.737 0.2092 0.0 0
M  V30 9 C -4.0097 -1.9525 0.0 0
M  V30 10 C 2.336 -4.1491 0.0 0
M  V30 11 C 3.6087 -1.9699 0.0 0
M  V30 12 O -4.062 0.9588 0.0 0
M  V30 13 C -0.5404 1.5864 0.0 0
M  V30 14 C -5.3172 -1.2029 0.0 0
M  V30 15 O 2.2837 -5.5612 0.0 0
M  V30 16 C 3.5564 -3.3821 0.0 0
M  V30 17 O 4.829 -1.2029 0.0 0
M  V30 18 C -5.3695 0.3138 0.0 0
M  V30 19 C -0.5927 3.1031 0.0 0
M  V30 20 C 0.6799 0.9239 0.0 0
M  V30 21 C -6.6421 -1.8653 0.0 0
M  V30 22 O 4.7767 -4.0445 0.0 0
M  V30 23 C -6.6944 1.0808 0.0 0
M  V30 24 C 0.6276 3.8702 0.0 0
M  V30 25 C -1.9176 3.8702 0.0 0
M  V30 26 C 1.9002 1.691 0.0 0
M  V30 27 O -6.6944 -3.2775 0.0 0
M  V30 28 C -7.9671 -1.0983 0.0 0
M  V30 29 C -8.0194 0.4184 0.0 0
M  V30 30 O 0.5753 5.3869 0.0 0
M  V30 31 C 1.8479 3.2077 0.0 0
M  V30 32 C -3.2426 3.2077 0.0 0
M  V30 33 C -1.9699 5.3869 0.0 0
M  V30 34 O 3.1206 1.0285 0.0 0
M  V30 35 O -9.3443 1.1854 0.0 0
M  V30 36 O 3.0683 3.9748 0.0 0
M  V30 37 O -3.2949 1.7956 0.0 0
M  V30 38 C -4.5675 3.9748 0.0 0
M  V30 39 C -3.2949 6.154 0.0 0
M  V30 40 C 0.2266 6.7642 0.0 0
M  V30 41 O -5.8925 3.3123 0.0 0
M  V30 42 C -4.6198 5.4915 0.0 0
M  V30 43 O 1.4469 6.1191 0.0 0
M  V30 44 C 0.1743 8.2809 0.0 0
M  V30 45 O -5.9448 6.2586 0.0 0
M  V30 46 C 2.6498 6.8688 0.0 0
M  V30 47 O -1.1331 9.0479 0.0 0
M  V30 48 C 1.3946 9.0305 0.0 0
M  V30 49 C 2.5975 8.3855 0.0 0
M  V30 50 C 3.8702 6.2063 0.0 0
M  V30 51 C -2.4581 8.3855 0.0 0
M  V30 52 C 3.8179 9.1525 0.0 0
M  V30 53 C 5.0905 6.9734 0.0 0
M  V30 54 O -2.5104 6.9734 0.0 0
M  V30 55 C -3.783 9.1525 0.0 0
M  V30 56 O 3.7656 10.6693 0.0 0
M  V30 57 C 5.0382 8.4901 0.0 0
M  V30 58 C 6.3109 6.3109 0.0 0
M  V30 59 C -5.108 8.4901 0.0 0
M  V30 60 C -3.8353 10.6693 0.0 0
M  V30 61 C -6.4329 9.2572 0.0 0
M  V30 62 C -5.1603 11.4363 0.0 0
M  V30 63 O -7.7579 8.5947 0.0 0
M  V30 64 C -6.4852 10.7739 0.0 0
M  V30 65 O -5.2126 12.9531 0.0 0
M  V30 66 O -7.8102 11.5409 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 2 7 11
M  V30 11 1 8 12
M  V30 12 1 8 13
M  V30 13 1 9 14
M  V30 14 1 10 15
M  V30 15 2 10 16
M  V30 16 1 11 17
M  V30 17 1 12 18
M  V30 18 2 13 19
M  V30 19 1 13 20
M  V30 20 1 14 21
M  V30 21 1 16 22
M  V30 22 1 18 23
M  V30 23 1 19 24
M  V30 24 1 19 25
M  V30 25 2 20 26
M  V30 26 1 21 27
M  V30 27 2 21 28
M  V30 28 2 23 29
M  V30 29 1 24 30
M  V30 30 2 24 31
M  V30 31 2 25 32
M  V30 32 1 25 33
M  V30 33 1 26 34
M  V30 34 1 29 35
M  V30 35 1 31 36
M  V30 36 1 32 37
M  V30 37 1 32 38
M  V30 38 2 33 39
M  V30 39 1 33 40
M  V30 40 1 38 41
M  V30 41 2 38 42
M  V30 42 1 40 43
M  V30 43 1 40 44
M  V30 44 1 42 45
M  V30 45 1 43 46
M  V30 46 1 44 47
M  V30 47 1 44 48
M  V30 48 2 46 49
M  V30 49 1 46 50
M  V30 50 1 47 51
M  V30 51 1 49 52
M  V30 52 2 50 53
M  V30 53 2 51 54
M  V30 54 1 51 55
M  V30 55 1 52 56
M  V30 56 2 52 57
M  V30 57 1 53 58
M  V30 58 2 55 59
M  V30 59 1 55 60
M  V30 60 1 59 61
M  V30 61 2 60 62
M  V30 62 1 61 63
M  V30 63 2 61 64
M  V30 64 1 62 65
M  V30 65 1 64 66
M  V30 66 1 11 16
M  V30 67 2 14 18
M  V30 68 1 26 31
M  V30 69 1 28 29
M  V30 70 1 39 42
M  V30 71 1 48 49
M  V30 72 1 53 57
M  V30 73 1 62 64
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000742A1-20220106-C00004

>  <Row No>
567

$$$$
US20220000743A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 138 126 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.1369 -0.6121 0.0 0
M  V30 3 O 0.9182 1.1806 0.0 0
M  V30 4 O -1.1806 -0.9182 0.0 0
M  V30 5 C -1.3992 0.8745 0.0 0
M  V30 6 C 2.2738 0.2623 0.0 0
M  V30 7 C -0.2623 2.3612 0.0 0
M  V30 8 C -0.5684 -2.0551 0.0 0
M  V30 9 C -2.7985 0.2623 0.0 0
M  V30 10 C 3.4107 -0.3498 0.0 0
M  V30 11 C -1.7928 2.0988 0.0 0
M  V30 12 C 0.6996 -1.5304 0.0 0
M  V30 13 N -4.1977 1.1369 0.0 0
M  V30 14 C -5.597 0.5247 0.0 0
M  V30 15 C -4.3289 2.7547 0.0 0
M  V30 16 Si -1.749 31.8332 0.0 0
M  V30 17 O -0.6121 31.221 0.0 0
M  V30 18 O -0.8308 33.0138 0.0 0
M  V30 19 O -2.9297 30.9149 0.0 0
M  V30 20 C -3.1483 32.7077 0.0 0
M  V30 21 C 0.5247 32.0955 0.0 0
M  V30 22 C -2.0114 34.1944 0.0 0
M  V30 23 C -2.3175 29.778 0.0 0
M  V30 24 C -4.5476 32.0955 0.0 0
M  V30 25 C 1.6616 31.4834 0.0 0
M  V30 26 C -3.5418 33.9321 0.0 0
M  V30 27 C -1.0494 30.3027 0.0 0
M  V30 28 N -5.9468 32.9701 0.0 0
M  V30 29 Si 0.0 19.2398 0.0 0
M  V30 30 O 1.1369 18.6276 0.0 0
M  V30 31 O 0.9182 20.4204 0.0 0
M  V30 32 O -1.1806 18.3215 0.0 0
M  V30 33 C -1.3992 20.1144 0.0 0
M  V30 34 C 2.2738 19.5022 0.0 0
M  V30 35 C -0.2623 21.6011 0.0 0
M  V30 36 C -0.5684 17.1846 0.0 0
M  V30 37 C -2.7985 19.5022 0.0 0
M  V30 38 C 3.4107 18.89 0.0 0
M  V30 39 C -1.7928 21.3387 0.0 0
M  V30 40 C 0.6996 17.7094 0.0 0
M  V30 41 C -4.1977 20.3767 0.0 0
M  V30 42 N -5.597 19.7645 0.0 0
M  V30 43 C -6.9963 20.6391 0.0 0
M  V30 44 C -5.7282 18.409 0.0 0
M  V30 45 Si -0.6996 44.7764 0.0 0
M  V30 46 O 0.4372 44.1642 0.0 0
M  V30 47 O 0.2186 45.957 0.0 0
M  V30 48 O -1.8802 43.8581 0.0 0
M  V30 49 C -2.0988 45.6509 0.0 0
M  V30 50 C 1.5741 45.0387 0.0 0
M  V30 51 C -0.9619 47.1376 0.0 0
M  V30 52 C -1.268 42.7212 0.0 0
M  V30 53 C -3.4981 45.0387 0.0 0
M  V30 54 C 2.711 44.4265 0.0 0
M  V30 55 C -2.4924 46.8753 0.0 0
M  V30 56 C 0.0 43.2459 0.0 0
M  V30 57 C -4.8974 45.9133 0.0 0
M  V30 58 N -6.2966 45.3011 0.0 0
M  V30 59 Si 0.0 -6.2966 0.0 0
M  V30 60 O 1.1369 -6.9088 0.0 0
M  V30 61 O 0.9182 -5.116 0.0 0
M  V30 62 O -1.1806 -7.2149 0.0 0
M  V30 63 C -1.3992 -5.4221 0.0 0
M  V30 64 C 2.2738 -6.0343 0.0 0
M  V30 65 C -0.2623 -3.9354 0.0 0
M  V30 66 C -0.5684 -8.3518 0.0 0
M  V30 67 C -2.7985 -6.0343 0.0 0
M  V30 68 N -4.1977 -5.1597 0.0 0
M  V30 69 C -5.597 -5.7719 0.0 0
M  V30 70 C -4.3289 -3.5418 0.0 0
M  V30 71 Si -1.3992 25.1867 0.0 0
M  V30 72 O -0.2623 24.5745 0.0 0
M  V30 73 O -0.4809 26.3673 0.0 0
M  V30 74 O -2.5798 24.2684 0.0 0
M  V30 75 C -2.7985 26.0612 0.0 0
M  V30 76 C 0.8745 25.449 0.0 0
M  V30 77 C -1.6616 27.5479 0.0 0
M  V30 78 C -1.9677 23.1315 0.0 0
M  V30 79 C -4.1977 25.449 0.0 0
M  V30 80 N -5.597 26.3236 0.0 0
M  V30 81 Si 0.6996 12.9431 0.0 0
M  V30 82 O 1.8365 12.331 0.0 0
M  V30 83 O 1.6178 14.1238 0.0 0
M  V30 84 O -0.4809 12.0249 0.0 0
M  V30 85 C -0.6996 13.8177 0.0 0
M  V30 86 C 2.9734 13.2055 0.0 0
M  V30 87 C 0.4372 15.3044 0.0 0
M  V30 88 C 0.1311 10.888 0.0 0
M  V30 89 C -2.0988 13.2055 0.0 0
M  V30 90 C -3.4981 14.08 0.0 0
M  V30 91 N -4.8974 13.4679 0.0 0
M  V30 92 C -6.2966 14.3424 0.0 0
M  V30 93 C -5.0286 12.1123 0.0 0
M  V30 94 Si -0.3498 38.4797 0.0 0
M  V30 95 O 0.787 37.8675 0.0 0
M  V30 96 O 0.5684 39.6603 0.0 0
M  V30 97 O -1.5304 37.5614 0.0 0
M  V30 98 C -1.749 39.3542 0.0 0
M  V30 99 C 1.9239 38.742 0.0 0
M  V30 100 C -0.6121 40.8409 0.0 0
M  V30 101 C -0.9182 36.4245 0.0 0
M  V30 102 C -3.1483 38.742 0.0 0
M  V30 103 C -4.5476 39.6166 0.0 0
M  V30 104 N -5.9468 39.0044 0.0 0
M  V30 105 Si -0.3498 -13.9926 0.0 0
M  V30 106 O 0.787 -14.6048 0.0 0
M  V30 107 O 0.5684 -12.812 0.0 0
M  V30 108 O -1.5304 -14.9108 0.0 0
M  V30 109 C -1.749 -13.118 0.0 0
M  V30 110 C -3.1483 -13.7302 0.0 0
M  V30 111 N -4.5476 -12.8557 0.0 0
M  V30 112 C -5.9468 -13.4679 0.0 0
M  V30 113 C -4.6787 -11.2378 0.0 0
M  V30 114 Si 6.9963 24.1372 0.0 0
M  V30 115 O 8.1332 23.5251 0.0 0
M  V30 116 O 7.9145 25.3179 0.0 0
M  V30 117 O 5.8156 23.219 0.0 0
M  V30 118 C 5.597 25.0118 0.0 0
M  V30 119 C 4.1977 24.3996 0.0 0
M  V30 120 N 2.7985 25.2741 0.0 0
M  V30 121 Si 0.3498 6.9963 0.0 0
M  V30 122 O 1.4867 6.3841 0.0 0
M  V30 123 O 1.268 8.1769 0.0 0
M  V30 124 O -0.8308 6.078 0.0 0
M  V30 125 C -1.0494 7.8708 0.0 0
M  V30 126 C -2.4487 7.2586 0.0 0
M  V30 127 C -3.8479 8.1332 0.0 0
M  V30 128 N -5.2472 7.521 0.0 0
M  V30 129 C -6.6464 8.3955 0.0 0
M  V30 130 C -5.3784 6.1655 0.0 0
M  V30 131 Si 8.7453 37.0804 0.0 0
M  V30 132 O 9.8822 36.4682 0.0 0
M  V30 133 O 9.6636 38.261 0.0 0
M  V30 134 O 7.5647 36.1622 0.0 0
M  V30 135 C 7.3461 37.955 0.0 0
M  V30 136 C 5.9468 37.3428 0.0 0
M  V30 137 C 4.5476 38.2173 0.0 0
M  V30 138 N 3.1483 37.6051 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 15 1 16 17
M  V30 16 1 16 18
M  V30 17 1 16 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 29 30
M  V30 28 1 29 31
M  V30 29 1 29 32
M  V30 30 1 29 33
M  V30 31 1 30 34
M  V30 32 1 31 35
M  V30 33 1 32 36
M  V30 34 1 33 37
M  V30 35 1 34 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 1 37 41
M  V30 39 1 41 42
M  V30 40 1 42 43
M  V30 41 1 42 44
M  V30 42 1 45 46
M  V30 43 1 45 47
M  V30 44 1 45 48
M  V30 45 1 45 49
M  V30 46 1 46 50
M  V30 47 1 47 51
M  V30 48 1 48 52
M  V30 49 1 49 53
M  V30 50 1 50 54
M  V30 51 1 51 55
M  V30 52 1 52 56
M  V30 53 1 53 57
M  V30 54 1 57 58
M  V30 55 1 59 60
M  V30 56 1 59 61
M  V30 57 1 59 62
M  V30 58 1 59 63
M  V30 59 1 60 64
M  V30 60 1 61 65
M  V30 61 1 62 66
M  V30 62 1 63 67
M  V30 63 1 67 68
M  V30 64 1 68 69
M  V30 65 1 68 70
M  V30 66 1 71 72
M  V30 67 1 71 73
M  V30 68 1 71 74
M  V30 69 1 71 75
M  V30 70 1 72 76
M  V30 71 1 73 77
M  V30 72 1 74 78
M  V30 73 1 75 79
M  V30 74 1 79 80
M  V30 75 1 81 82
M  V30 76 1 81 83
M  V30 77 1 81 84
M  V30 78 1 81 85
M  V30 79 1 82 86
M  V30 80 1 83 87
M  V30 81 1 84 88
M  V30 82 1 85 89
M  V30 83 1 89 90
M  V30 84 1 90 91
M  V30 85 1 91 92
M  V30 86 1 91 93
M  V30 87 1 94 95
M  V30 88 1 94 96
M  V30 89 1 94 97
M  V30 90 1 94 98
M  V30 91 1 95 99
M  V30 92 1 96 100
M  V30 93 1 97 101
M  V30 94 1 98 102
M  V30 95 1 102 103
M  V30 96 1 103 104
M  V30 97 1 105 106
M  V30 98 1 105 107
M  V30 99 1 105 108
M  V30 100 1 105 109
M  V30 101 1 109 110
M  V30 102 1 110 111
M  V30 103 1 111 112
M  V30 104 1 111 113
M  V30 105 1 114 115
M  V30 106 1 114 116
M  V30 107 1 114 117
M  V30 108 1 114 118
M  V30 109 1 118 119
M  V30 110 1 119 120
M  V30 111 1 121 122
M  V30 112 1 121 123
M  V30 113 1 121 124
M  V30 114 1 121 125
M  V30 115 1 125 126
M  V30 116 1 126 127
M  V30 117 1 127 128
M  V30 118 1 128 129
M  V30 119 1 128 130
M  V30 120 1 131 132
M  V30 121 1 131 133
M  V30 122 1 131 134
M  V30 123 1 131 135
M  V30 124 1 135 136
M  V30 125 1 136 137
M  V30 126 1 137 138
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000743A1-20220106-C00001

>  <Row No>
568

$$$$
US20220000743A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 152 146 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -0.9267 1.4828 0.0 0
M  V30 3 O 0.6487 -1.2048 0.0 0
M  V30 4 O -1.4828 -0.6487 0.0 0
M  V30 5 C 1.2048 0.9267 0.0 0
M  V30 6 C -0.6487 3.1047 0.0 0
M  V30 7 C 2.0389 -1.0658 0.0 0
M  V30 8 C -2.9657 0.278 0.0 0
M  V30 9 C 2.4096 0.278 0.0 0
M  V30 10 C 0.7414 3.2437 0.0 0
M  V30 11 C 2.6876 -2.2706 0.0 0
M  V30 12 C -4.4485 -0.3707 0.0 0
M  V30 13 C 3.6144 1.2048 0.0 0
M  V30 14 N 4.8193 0.556 0.0 0
M  V30 15 C 4.6802 -0.8341 0.0 0
M  V30 16 C 6.0241 1.4828 0.0 0
M  V30 17 C 5.8851 -1.4828 0.0 0
M  V30 18 C 7.2289 0.8341 0.0 0
M  V30 19 O 5.746 -2.873 0.0 0
M  V30 20 C 8.4337 1.7609 0.0 0
M  V30 21 Si 9.6386 1.1121 0.0 0
M  V30 22 O 10.6117 2.3633 0.0 0
M  V30 23 O 10.8434 0.4633 0.0 0
M  V30 24 O 8.3874 0.139 0.0 0
M  V30 25 C 9.3605 3.6144 0.0 0
M  V30 26 C 12.2336 0.6024 0.0 0
M  V30 27 C 8.2484 -1.2511 0.0 0
M  V30 28 C 10.3337 4.8656 0.0 0
M  V30 29 C 13.2067 1.8535 0.0 0
M  V30 30 C 9.5922 -1.5292 0.0 0
M  V30 31 Si -1.8535 21.5015 0.0 0
M  V30 32 O -2.7803 22.9843 0.0 0
M  V30 33 O -1.2048 20.2967 0.0 0
M  V30 34 O -3.3364 20.8527 0.0 0
M  V30 35 C -0.6487 22.4283 0.0 0
M  V30 36 C -2.5023 24.6062 0.0 0
M  V30 37 C 0.1853 20.4357 0.0 0
M  V30 38 C -4.8193 21.7795 0.0 0
M  V30 39 C 0.556 21.7795 0.0 0
M  V30 40 C -1.1121 24.7452 0.0 0
M  V30 41 C 0.8341 19.2308 0.0 0
M  V30 42 C -6.3021 21.1308 0.0 0
M  V30 43 C 1.7609 22.7063 0.0 0
M  V30 44 N 2.9657 22.0576 0.0 0
M  V30 45 C 4.1705 22.9843 0.0 0
M  V30 46 C 2.8267 20.6674 0.0 0
M  V30 47 C 5.3753 22.3356 0.0 0
M  V30 48 C 6.5802 23.2624 0.0 0
M  V30 49 Si 7.785 22.6136 0.0 0
M  V30 50 O 8.7581 23.8648 0.0 0
M  V30 51 O 8.9898 21.9649 0.0 0
M  V30 52 O 6.5338 21.6405 0.0 0
M  V30 53 C 7.5069 25.116 0.0 0
M  V30 54 C 10.38 22.1039 0.0 0
M  V30 55 C 6.3948 20.2503 0.0 0
M  V30 56 C 8.4801 26.3671 0.0 0
M  V30 57 C 11.3531 23.3551 0.0 0
M  V30 58 C 7.7386 19.9723 0.0 0
M  V30 59 Si -1.1121 38.5544 0.0 0
M  V30 60 O -2.0389 40.0373 0.0 0
M  V30 61 O -0.4633 37.3496 0.0 0
M  V30 62 O -2.595 37.9057 0.0 0
M  V30 63 C 0.0926 39.4812 0.0 0
M  V30 64 C -1.7609 41.6592 0.0 0
M  V30 65 C 0.9267 37.4886 0.0 0
M  V30 66 C -4.0778 38.8325 0.0 0
M  V30 67 C 1.2975 38.8325 0.0 0
M  V30 68 C -0.3707 41.7982 0.0 0
M  V30 69 C 1.5755 36.2838 0.0 0
M  V30 70 C -5.5607 38.1837 0.0 0
M  V30 71 C 2.5023 39.7592 0.0 0
M  V30 72 N 3.7071 39.1105 0.0 0
M  V30 73 C 4.9119 40.0373 0.0 0
M  V30 74 C 6.1168 39.3885 0.0 0
M  V30 75 C 7.3216 40.3153 0.0 0
M  V30 76 Si 8.5264 39.6666 0.0 0
M  V30 77 O 9.4995 40.9177 0.0 0
M  V30 78 O 9.7312 39.0178 0.0 0
M  V30 79 O 7.2753 38.6934 0.0 0
M  V30 80 C 8.2484 42.1689 0.0 0
M  V30 81 C 11.1214 39.1568 0.0 0
M  V30 82 C 7.1362 37.3033 0.0 0
M  V30 83 C 9.2215 43.4201 0.0 0
M  V30 84 C 12.0946 40.408 0.0 0
M  V30 85 C 8.4801 37.0252 0.0 0
M  V30 86 Si -2.595 11.8629 0.0 0
M  V30 87 O -4.0778 11.2141 0.0 0
M  V30 88 O -1.9462 10.658 0.0 0
M  V30 89 O -3.5218 13.3457 0.0 0
M  V30 90 C -1.3901 12.7897 0.0 0
M  V30 91 C -5.5607 12.1409 0.0 0
M  V30 92 C -0.556 10.7971 0.0 0
M  V30 93 C -3.2437 14.9676 0.0 0
M  V30 94 C -0.1853 12.1409 0.0 0
M  V30 95 C 1.0194 13.0677 0.0 0
M  V30 96 N 2.2242 12.4189 0.0 0
M  V30 97 C 2.0852 11.0288 0.0 0
M  V30 98 C 3.4291 13.3457 0.0 0
M  V30 99 C 3.4291 10.7507 0.0 0
M  V30 100 C 4.6339 12.697 0.0 0
M  V30 101 O 3.2901 9.3605 0.0 0
M  V30 102 C 5.8387 13.6238 0.0 0
M  V30 103 Si 7.0436 12.975 0.0 0
M  V30 104 O 8.2484 12.3263 0.0 0
M  V30 105 O 8.0167 14.2262 0.0 0
M  V30 106 O 5.7924 12.0019 0.0 0
M  V30 107 C 9.6386 12.4653 0.0 0
M  V30 108 C 6.7655 15.4773 0.0 0
M  V30 109 C 5.6534 10.6117 0.0 0
M  V30 110 Si -1.8535 29.6572 0.0 0
M  V30 111 O -3.3364 29.0085 0.0 0
M  V30 112 O -1.2048 28.4524 0.0 0
M  V30 113 O -2.7803 31.1401 0.0 0
M  V30 114 C -0.6487 30.584 0.0 0
M  V30 115 C -4.8193 29.9353 0.0 0
M  V30 116 C 0.1853 28.5914 0.0 0
M  V30 117 C -2.5023 32.762 0.0 0
M  V30 118 C 0.556 29.9353 0.0 0
M  V30 119 C 1.7609 30.8621 0.0 0
M  V30 120 N 2.9657 30.2133 0.0 0
M  V30 121 C 4.1705 31.1401 0.0 0
M  V30 122 C 2.8267 28.8231 0.0 0
M  V30 123 C 5.3753 30.4913 0.0 0
M  V30 124 C 6.5802 31.4181 0.0 0
M  V30 125 Si 7.785 30.7694 0.0 0
M  V30 126 O 8.9898 30.1206 0.0 0
M  V30 127 O 8.7581 32.0205 0.0 0
M  V30 128 O 6.5338 29.7963 0.0 0
M  V30 129 C 10.38 30.2596 0.0 0
M  V30 130 C 7.5069 33.2717 0.0 0
M  V30 131 C 6.3948 28.4061 0.0 0
M  V30 132 Si -1.8535 47.4516 0.0 0
M  V30 133 O -3.3364 46.8028 0.0 0
M  V30 134 O -1.2048 46.2468 0.0 0
M  V30 135 O -2.7803 48.9345 0.0 0
M  V30 136 C -0.6487 48.3784 0.0 0
M  V30 137 C -4.8193 47.7296 0.0 0
M  V30 138 C 0.1853 46.3858 0.0 0
M  V30 139 C -2.5023 50.5563 0.0 0
M  V30 140 C 0.556 47.7296 0.0 0
M  V30 141 C 1.7609 48.6564 0.0 0
M  V30 142 N 2.9657 48.0077 0.0 0
M  V30 143 C 4.1705 48.9345 0.0 0
M  V30 144 C 5.3753 48.2857 0.0 0
M  V30 145 C 6.5802 49.2125 0.0 0
M  V30 146 Si 7.785 48.5637 0.0 0
M  V30 147 O 8.9898 47.915 0.0 0
M  V30 148 O 8.7581 49.8149 0.0 0
M  V30 149 O 6.5338 47.5906 0.0 0
M  V30 150 C 10.38 48.054 0.0 0
M  V30 151 C 7.5069 51.0661 0.0 0
M  V30 152 C 6.3948 46.2004 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 47 48
M  V30 47 1 48 49
M  V30 48 1 49 50
M  V30 49 1 49 51
M  V30 50 1 49 52
M  V30 51 1 50 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 59 60
M  V30 58 1 59 61
M  V30 59 1 59 62
M  V30 60 1 59 63
M  V30 61 1 60 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 71 72
M  V30 70 1 72 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 75 76
M  V30 74 1 76 77
M  V30 75 1 76 78
M  V30 76 1 76 79
M  V30 77 1 77 80
M  V30 78 1 78 81
M  V30 79 1 79 82
M  V30 80 1 80 83
M  V30 81 1 81 84
M  V30 82 1 82 85
M  V30 83 1 86 87
M  V30 84 1 86 88
M  V30 85 1 86 89
M  V30 86 1 86 90
M  V30 87 1 87 91
M  V30 88 1 88 92
M  V30 89 1 89 93
M  V30 90 1 90 94
M  V30 91 1 94 95
M  V30 92 1 95 96
M  V30 93 1 96 97
M  V30 94 1 96 98
M  V30 95 1 97 99
M  V30 96 1 98 100
M  V30 97 1 99 101
M  V30 98 1 100 102
M  V30 99 1 102 103
M  V30 100 1 103 104
M  V30 101 1 103 105
M  V30 102 1 103 106
M  V30 103 1 104 107
M  V30 104 1 105 108
M  V30 105 1 106 109
M  V30 106 1 110 111
M  V30 107 1 110 112
M  V30 108 1 110 113
M  V30 109 1 110 114
M  V30 110 1 111 115
M  V30 111 1 112 116
M  V30 112 1 113 117
M  V30 113 1 114 118
M  V30 114 1 118 119
M  V30 115 1 119 120
M  V30 116 1 120 121
M  V30 117 1 120 122
M  V30 118 1 121 123
M  V30 119 1 123 124
M  V30 120 1 124 125
M  V30 121 1 125 126
M  V30 122 1 125 127
M  V30 123 1 125 128
M  V30 124 1 126 129
M  V30 125 1 127 130
M  V30 126 1 128 131
M  V30 127 1 132 133
M  V30 128 1 132 134
M  V30 129 1 132 135
M  V30 130 1 132 136
M  V30 131 1 133 137
M  V30 132 1 134 138
M  V30 133 1 135 139
M  V30 134 1 136 140
M  V30 135 1 140 141
M  V30 136 1 141 142
M  V30 137 1 142 143
M  V30 138 1 143 144
M  V30 139 1 144 145
M  V30 140 1 145 146
M  V30 141 1 146 147
M  V30 142 1 146 148
M  V30 143 1 146 149
M  V30 144 1 147 150
M  V30 145 1 148 151
M  V30 146 1 149 152
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000743A1-20220106-C00002

>  <Row No>
569

$$$$
US20220000743A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 179 173 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -0.9474 1.5048 0.0 0
M  V30 3 O -1.5048 -0.613 0.0 0
M  V30 4 O 0.613 -1.1704 0.0 0
M  V30 5 C 1.1704 0.9474 0.0 0
M  V30 6 C -0.7245 3.1769 0.0 0
M  V30 7 C -3.0096 0.3344 0.0 0
M  V30 8 C 2.0064 -1.0032 0.0 0
M  V30 9 C 2.3408 0.3344 0.0 0
M  V30 10 C 0.6688 3.3441 0.0 0
M  V30 11 C -4.5145 -0.2786 0.0 0
M  V30 12 C 2.6195 -2.1736 0.0 0
M  V30 13 C 3.5113 1.2819 0.0 0
M  V30 14 N 4.6817 0.6688 0.0 0
M  V30 15 C 4.5145 -0.7245 0.0 0
M  V30 16 C 5.8521 1.6163 0.0 0
M  V30 17 C 5.6849 -1.3376 0.0 0
M  V30 18 C 7.0226 1.0032 0.0 0
M  V30 19 C 5.5177 -2.731 0.0 0
M  V30 20 C 8.193 1.9507 0.0 0
M  V30 21 Si 9.3635 1.3376 0.0 0
M  V30 22 O 10.3109 2.6195 0.0 0
M  V30 23 O 10.5339 0.7245 0.0 0
M  V30 24 O 8.0815 0.3901 0.0 0
M  V30 25 C 9.029 3.9014 0.0 0
M  V30 26 C 11.9273 0.8917 0.0 0
M  V30 27 C 7.9143 -1.0032 0.0 0
M  V30 28 C 9.9765 5.1833 0.0 0
M  V30 29 C 12.8748 2.1736 0.0 0
M  V30 30 C 9.252 -1.2261 0.0 0
M  V30 31 Si -1.3376 21.8481 0.0 0
M  V30 32 O -2.2851 23.353 0.0 0
M  V30 33 O -2.8424 21.235 0.0 0
M  V30 34 O -0.7245 20.6777 0.0 0
M  V30 35 C -0.1672 22.7956 0.0 0
M  V30 36 C -2.0621 25.025 0.0 0
M  V30 37 C -4.3473 22.1825 0.0 0
M  V30 38 C 0.6688 20.8449 0.0 0
M  V30 39 C 1.0032 22.1825 0.0 0
M  V30 40 C -0.6688 25.1922 0.0 0
M  V30 41 C -5.8521 21.5694 0.0 0
M  V30 42 C 1.2819 19.6744 0.0 0
M  V30 43 C 2.1736 23.13 0.0 0
M  V30 44 N 3.3441 22.5169 0.0 0
M  V30 45 C 3.1769 21.1236 0.0 0
M  V30 46 C 4.5145 23.4644 0.0 0
M  V30 47 C 4.3473 20.5105 0.0 0
M  V30 48 C 5.6849 22.8513 0.0 0
M  V30 49 N 4.1801 19.1171 0.0 0
M  V30 50 C 6.8554 23.7988 0.0 0
M  V30 51 Si 8.0258 23.1858 0.0 0
M  V30 52 O 8.9733 24.4677 0.0 0
M  V30 53 O 9.1962 22.5727 0.0 0
M  V30 54 O 6.7439 22.2383 0.0 0
M  V30 55 C 7.6914 25.7496 0.0 0
M  V30 56 C 10.5896 22.7399 0.0 0
M  V30 57 C 6.5767 20.8449 0.0 0
M  V30 58 C 8.6389 27.0315 0.0 0
M  V30 59 C 11.5371 24.0218 0.0 0
M  V30 60 C 7.9143 20.6219 0.0 0
M  V30 61 Si -1.3376 44.1422 0.0 0
M  V30 62 O -2.2851 45.647 0.0 0
M  V30 63 O -2.8424 43.5291 0.0 0
M  V30 64 O -0.7245 42.9717 0.0 0
M  V30 65 C -0.1672 45.0897 0.0 0
M  V30 66 C -2.0621 47.3191 0.0 0
M  V30 67 C -4.3473 44.4766 0.0 0
M  V30 68 C -2.0064 42.0242 0.0 0
M  V30 69 C 1.0032 44.4766 0.0 0
M  V30 70 C -0.6688 47.4863 0.0 0
M  V30 71 C -5.8521 43.8635 0.0 0
M  V30 72 C -1.7835 40.6866 0.0 0
M  V30 73 C 2.1736 45.4241 0.0 0
M  V30 74 N 3.3441 44.811 0.0 0
M  V30 75 C 4.5145 45.7585 0.0 0
M  V30 76 C 3.1769 43.4176 0.0 0
M  V30 77 C 5.6849 45.1454 0.0 0
M  V30 78 C 4.3473 42.8045 0.0 0
M  V30 79 C 6.8554 46.0929 0.0 0
M  V30 80 C 4.1801 41.4111 0.0 0
M  V30 81 Si 8.0258 45.4798 0.0 0
M  V30 82 Si 2.6752 40.7981 0.0 0
M  V30 83 O 8.9733 46.7617 0.0 0
M  V30 84 O 9.1962 44.8667 0.0 0
M  V30 85 O 6.7439 44.5323 0.0 0
M  V30 86 O 3.8457 40.185 0.0 0
M  V30 87 O 1.1704 40.185 0.0 0
M  V30 88 O 1.1704 41.7456 0.0 0
M  V30 89 C 7.6914 48.0436 0.0 0
M  V30 90 C 10.5896 45.0339 0.0 0
M  V30 91 C 6.5767 43.1389 0.0 0
M  V30 92 C 5.1833 40.7423 0.0 0
M  V30 93 C -0.3344 41.1325 0.0 0
M  V30 94 C 1.0032 43.4733 0.0 0
M  V30 95 C 6.0193 47.8207 0.0 0
M  V30 96 C 10.8126 46.706 0.0 0
M  V30 97 C 7.9701 43.3061 0.0 0
M  V30 98 C 6.1308 39.7948 0.0 0
M  V30 99 C -1.6163 40.185 0.0 0
M  V30 100 C -0.5016 44.4208 0.0 0
M  V30 101 Si -2.6752 11.5929 0.0 0
M  V30 102 O -4.1801 10.9798 0.0 0
M  V30 103 O -2.0621 10.4224 0.0 0
M  V30 104 O -3.6227 13.0977 0.0 0
M  V30 105 C -1.5048 12.5404 0.0 0
M  V30 106 C -5.6849 11.9273 0.0 0
M  V30 107 C -0.6688 10.5896 0.0 0
M  V30 108 C -3.3998 14.7698 0.0 0
M  V30 109 C -0.3344 11.9273 0.0 0
M  V30 110 C 0.836 12.8748 0.0 0
M  V30 111 N 2.0064 12.2617 0.0 0
M  V30 112 C 1.8392 10.8683 0.0 0
M  V30 113 C 3.1769 13.2092 0.0 0
M  V30 114 C 3.1769 10.6454 0.0 0
M  V30 115 C 4.3473 12.5961 0.0 0
M  V30 116 C 3.0096 9.252 0.0 0
M  V30 117 C 5.5177 13.5436 0.0 0
M  V30 118 Si 6.6882 12.9305 0.0 0
M  V30 119 O 7.8586 12.3174 0.0 0
M  V30 120 O 7.6357 14.2124 0.0 0
M  V30 121 O 5.4063 11.983 0.0 0
M  V30 122 C 9.252 12.4846 0.0 0
M  V30 123 C 6.3538 15.4943 0.0 0
M  V30 124 C 5.2391 10.5896 0.0 0
M  V30 125 Si -2.6752 31.6575 0.0 0
M  V30 126 O -4.1801 31.0444 0.0 0
M  V30 127 O -2.0621 30.4871 0.0 0
M  V30 128 O -3.6227 33.1623 0.0 0
M  V30 129 C -1.5048 32.605 0.0 0
M  V30 130 C -5.6849 31.9919 0.0 0
M  V30 131 C -0.6688 30.6543 0.0 0
M  V30 132 C -3.3998 34.8344 0.0 0
M  V30 133 C -0.3344 31.9919 0.0 0
M  V30 134 C 0.836 32.9394 0.0 0
M  V30 135 N 2.0064 32.3263 0.0 0
M  V30 136 C 1.8392 30.9329 0.0 0
M  V30 137 C 3.1769 33.2738 0.0 0
M  V30 138 C 3.1769 30.71 0.0 0
M  V30 139 C 4.3473 32.6607 0.0 0
M  V30 140 N 3.0096 29.3166 0.0 0
M  V30 141 C 5.5177 33.6082 0.0 0
M  V30 142 Si 6.6882 32.9951 0.0 0
M  V30 143 O 7.8586 32.3821 0.0 0
M  V30 144 O 7.6357 34.277 0.0 0
M  V30 145 O 5.4063 32.0476 0.0 0
M  V30 146 C 9.252 32.5493 0.0 0
M  V30 147 C 6.3538 35.559 0.0 0
M  V30 148 C 5.2391 30.6543 0.0 0
M  V30 149 Si -2.2294 57.0727 0.0 0
M  V30 150 O -3.7342 56.4596 0.0 0
M  V30 151 O -1.6163 55.9023 0.0 0
M  V30 152 O -3.1769 58.5776 0.0 0
M  V30 153 C -1.0589 58.0202 0.0 0
M  V30 154 C -5.2391 57.4071 0.0 0
M  V30 155 C -0.2229 56.0695 0.0 0
M  V30 156 C -2.9539 60.2496 0.0 0
M  V30 157 C 0.1114 57.4071 0.0 0
M  V30 158 C 1.2819 58.3546 0.0 0
M  V30 159 N 2.4523 57.7415 0.0 0
M  V30 160 C 3.6227 58.689 0.0 0
M  V30 161 C 2.2851 56.3482 0.0 0
M  V30 162 C 4.7932 58.0759 0.0 0
M  V30 163 C 3.4555 55.7351 0.0 0
M  V30 164 C 5.9636 59.0234 0.0 0
M  V30 165 C 3.2883 54.3417 0.0 0
M  V30 166 Si 7.134 58.4104 0.0 0
M  V30 167 Si 1.7835 53.7286 0.0 0
M  V30 168 O 8.3045 57.7973 0.0 0
M  V30 169 O 8.0815 59.6923 0.0 0
M  V30 170 O 5.8521 57.4629 0.0 0
M  V30 171 O 0.2786 54.6761 0.0 0
M  V30 172 O 0.2786 53.1155 0.0 0
M  V30 173 O 2.9539 53.1155 0.0 0
M  V30 174 C 9.6979 57.9645 0.0 0
M  V30 175 C 6.7996 60.9742 0.0 0
M  V30 176 C 5.6849 56.0695 0.0 0
M  V30 177 C 0.1114 56.4039 0.0 0
M  V30 178 C -1.2261 54.063 0.0 0
M  V30 179 C 4.2916 53.6729 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 46 48
M  V30 47 1 47 49
M  V30 48 1 48 50
M  V30 49 1 50 51
M  V30 50 1 51 52
M  V30 51 1 51 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 56 59
M  V30 58 1 57 60
M  V30 59 1 61 62
M  V30 60 1 61 63
M  V30 61 1 61 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 68 72
M  V30 70 1 69 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 74 76
M  V30 74 1 75 77
M  V30 75 1 76 78
M  V30 76 1 77 79
M  V30 77 1 78 80
M  V30 78 1 79 81
M  V30 79 1 80 82
M  V30 80 1 81 83
M  V30 81 1 81 84
M  V30 82 1 81 85
M  V30 83 1 82 86
M  V30 84 1 82 87
M  V30 85 1 82 88
M  V30 86 1 83 89
M  V30 87 1 84 90
M  V30 88 1 85 91
M  V30 89 1 86 92
M  V30 90 1 87 93
M  V30 91 1 88 94
M  V30 92 1 89 95
M  V30 93 1 90 96
M  V30 94 1 91 97
M  V30 95 1 92 98
M  V30 96 1 93 99
M  V30 97 1 94 100
M  V30 98 1 101 102
M  V30 99 1 101 103
M  V30 100 1 101 104
M  V30 101 1 101 105
M  V30 102 1 102 106
M  V30 103 1 103 107
M  V30 104 1 104 108
M  V30 105 1 105 109
M  V30 106 1 109 110
M  V30 107 1 110 111
M  V30 108 1 111 112
M  V30 109 1 111 113
M  V30 110 1 112 114
M  V30 111 1 113 115
M  V30 112 2 114 116
M  V30 113 1 115 117
M  V30 114 1 117 118
M  V30 115 1 118 119
M  V30 116 1 118 120
M  V30 117 1 118 121
M  V30 118 1 119 122
M  V30 119 1 120 123
M  V30 120 1 121 124
M  V30 121 1 125 126
M  V30 122 1 125 127
M  V30 123 1 125 128
M  V30 124 1 125 129
M  V30 125 1 126 130
M  V30 126 1 127 131
M  V30 127 1 128 132
M  V30 128 1 129 133
M  V30 129 1 133 134
M  V30 130 1 134 135
M  V30 131 1 135 136
M  V30 132 1 135 137
M  V30 133 1 136 138
M  V30 134 1 137 139
M  V30 135 1 138 140
M  V30 136 1 139 141
M  V30 137 1 141 142
M  V30 138 1 142 143
M  V30 139 1 142 144
M  V30 140 1 142 145
M  V30 141 1 143 146
M  V30 142 1 144 147
M  V30 143 1 145 148
M  V30 144 1 149 150
M  V30 145 1 149 151
M  V30 146 1 149 152
M  V30 147 1 149 153
M  V30 148 1 150 154
M  V30 149 1 151 155
M  V30 150 1 152 156
M  V30 151 1 153 157
M  V30 152 1 157 158
M  V30 153 1 158 159
M  V30 154 1 159 160
M  V30 155 1 159 161
M  V30 156 1 160 162
M  V30 157 1 161 163
M  V30 158 1 162 164
M  V30 159 1 163 165
M  V30 160 1 164 166
M  V30 161 1 165 167
M  V30 162 1 166 168
M  V30 163 1 166 169
M  V30 164 1 166 170
M  V30 165 1 167 171
M  V30 166 1 167 172
M  V30 167 1 167 173
M  V30 168 1 168 174
M  V30 169 1 169 175
M  V30 170 1 170 176
M  V30 171 1 171 177
M  V30 172 1 172 178
M  V30 173 1 173 179
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022002.cdx

>  <name>
US20220000743A1-20220106-C00003

>  <Row No>
570

$$$$
US20220000743A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 143 133 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.207 -0.8921 0.0 0
M  V30 3 O 1.1021 -0.5772 0.0 0
M  V30 4 O 0.8921 1.207 0.0 0
M  V30 5 C -1.4169 0.8921 0.0 0
M  V30 6 C -0.6297 -1.9942 0.0 0
M  V30 7 C 2.2042 0.3148 0.0 0
M  V30 8 C -0.3148 2.4141 0.0 0
M  V30 9 C -2.8339 0.3148 0.0 0
M  V30 10 C 0.6297 -1.4694 0.0 0
M  V30 11 C 3.3063 -0.2624 0.0 0
M  V30 12 C 0.2624 3.8311 0.0 0
M  V30 13 C -4.2509 1.207 0.0 0
M  V30 14 C -5.6679 0.6297 0.0 0
M  V30 15 C -7.0849 1.5219 0.0 0
M  V30 16 C -8.5019 0.9446 0.0 0
M  V30 17 C -9.9189 1.8368 0.0 0
M  V30 18 C -11.3359 1.2595 0.0 0
M  V30 19 C -12.7529 2.1517 0.0 0
M  V30 20 C -14.1699 1.5744 0.0 0
M  V30 21 C -15.5869 2.4666 0.0 0
M  V30 22 C -17.0039 1.8893 0.0 0
M  V30 23 Si -5.0382 16.3741 0.0 0
M  V30 24 O -6.2452 15.4819 0.0 0
M  V30 25 O -3.936 15.7968 0.0 0
M  V30 26 O -4.146 17.5812 0.0 0
M  V30 27 C -6.4551 17.2663 0.0 0
M  V30 28 C -5.6679 14.3798 0.0 0
M  V30 29 C -2.8339 16.689 0.0 0
M  V30 30 C -5.353 18.7883 0.0 0
M  V30 31 C -7.8721 16.689 0.0 0
M  V30 32 C -4.4084 14.9046 0.0 0
M  V30 33 C -1.7318 16.1117 0.0 0
M  V30 34 C -4.4609 19.9953 0.0 0
M  V30 35 C -9.2891 17.5812 0.0 0
M  V30 36 C -10.7061 17.0039 0.0 0
M  V30 37 C -12.1231 17.8961 0.0 0
M  V30 38 C -13.5401 17.3188 0.0 0
M  V30 39 C -14.9571 18.211 0.0 0
M  V30 40 C -16.3741 17.6337 0.0 0
M  V30 41 Si -7.5573 30.2292 0.0 0
M  V30 42 O -8.7643 29.337 0.0 0
M  V30 43 O -6.4551 29.6519 0.0 0
M  V30 44 O -6.6651 31.4362 0.0 0
M  V30 45 C -8.9743 31.1214 0.0 0
M  V30 46 C -8.187 28.2349 0.0 0
M  V30 47 C -5.353 30.5441 0.0 0
M  V30 48 C -7.8721 32.6433 0.0 0
M  V30 49 C -10.3912 30.5441 0.0 0
M  V30 50 C -6.9275 28.7597 0.0 0
M  V30 51 C -4.2509 29.9668 0.0 0
M  V30 52 C -6.98 33.8504 0.0 0
M  V30 53 C -11.8082 31.4362 0.0 0
M  V30 54 C -13.2252 30.8589 0.0 0
M  V30 55 C -14.6422 31.7511 0.0 0
M  V30 56 C -16.0592 31.1738 0.0 0
M  V30 57 Si -1.6794 8.8168 0.0 0
M  V30 58 O -0.5772 8.2395 0.0 0
M  V30 59 O -0.8397 9.9714 0.0 0
M  V30 60 O -2.8339 7.9771 0.0 0
M  V30 61 C -3.0963 9.709 0.0 0
M  V30 62 C 0.5248 9.1317 0.0 0
M  V30 63 C -1.9942 11.126 0.0 0
M  V30 64 C -2.2566 6.875 0.0 0
M  V30 65 C -4.5133 9.1317 0.0 0
M  V30 66 C -5.9303 10.0239 0.0 0
M  V30 67 C -7.3473 9.4466 0.0 0
M  V30 68 C -8.7643 10.3388 0.0 0
M  V30 69 C -10.1813 9.7615 0.0 0
M  V30 70 C -11.5983 10.6537 0.0 0
M  V30 71 C -13.0153 10.0764 0.0 0
M  V30 72 C -14.4323 10.9685 0.0 0
M  V30 73 C -15.8493 10.3912 0.0 0
M  V30 74 C -17.2663 11.2834 0.0 0
M  V30 75 C -18.6833 10.7061 0.0 0
M  V30 76 Si -5.0382 23.9314 0.0 0
M  V30 77 O -3.936 23.3541 0.0 0
M  V30 78 O -4.146 25.1385 0.0 0
M  V30 79 O -6.2452 23.0392 0.0 0
M  V30 80 C -6.4551 24.8236 0.0 0
M  V30 81 C -2.8339 24.2463 0.0 0
M  V30 82 C -5.353 26.3456 0.0 0
M  V30 83 C -5.6679 21.9371 0.0 0
M  V30 84 C -7.8721 24.2463 0.0 0
M  V30 85 C -9.2891 25.1385 0.0 0
M  V30 86 C -10.7061 24.5612 0.0 0
M  V30 87 C -12.1231 25.4534 0.0 0
M  V30 88 C -13.5401 24.8761 0.0 0
M  V30 89 C -14.9571 25.7683 0.0 0
M  V30 90 C -16.3741 25.191 0.0 0
M  V30 91 Si -7.5573 38.6262 0.0 0
M  V30 92 O -6.4551 38.0489 0.0 0
M  V30 93 O -6.6651 39.8332 0.0 0
M  V30 94 O -8.7643 37.734 0.0 0
M  V30 95 C -8.9743 39.5184 0.0 0
M  V30 96 C -5.353 38.9411 0.0 0
M  V30 97 C -7.8721 41.0403 0.0 0
M  V30 98 C -8.187 36.6319 0.0 0
M  V30 99 C -10.3912 38.9411 0.0 0
M  V30 100 C -11.8082 39.8332 0.0 0
M  V30 101 C -13.2252 39.256 0.0 0
M  V30 102 C -14.6422 40.1481 0.0 0
M  V30 103 C -16.0592 39.5708 0.0 0
M  V30 104 Si -6.2977 45.3438 0.0 0
M  V30 105 O -5.4055 46.5509 0.0 0
M  V30 106 O -5.1956 44.7665 0.0 0
M  V30 107 O -7.5048 44.4516 0.0 0
M  V30 108 C -7.7147 46.236 0.0 0
M  V30 109 C -6.6126 47.7579 0.0 0
M  V30 110 C -4.0935 45.6587 0.0 0
M  V30 111 C -6.9275 43.3495 0.0 0
M  V30 112 C -9.1317 45.6587 0.0 0
M  V30 113 C -5.7204 48.965 0.0 0
M  V30 114 C -2.9914 45.0814 0.0 0
M  V30 115 C -5.6154 43.5069 0.0 0
M  V30 116 Si -12.1756 45.3438 0.0 0
M  V30 117 O -11.0735 44.7665 0.0 0
M  V30 118 O -11.2834 46.5509 0.0 0
M  V30 119 O -13.3827 44.4516 0.0 0
M  V30 120 C -13.5926 46.236 0.0 0
M  V30 121 C -9.9714 45.6587 0.0 0
M  V30 122 C -12.4905 47.7579 0.0 0
M  V30 123 C -12.8054 43.3495 0.0 0
M  V30 124 C -15.0096 45.6587 0.0 0
M  V30 125 Si -7.1374 53.7408 0.0 0
M  V30 126 O -6.0353 53.1635 0.0 0
M  V30 127 O -6.2452 54.9479 0.0 0
M  V30 128 O -8.3445 52.8486 0.0 0
M  V30 129 C -8.5544 54.633 0.0 0
M  V30 130 C -4.9332 54.0557 0.0 0
M  V30 131 C -7.4523 56.1549 0.0 0
M  V30 132 C -7.7672 51.7465 0.0 0
M  V30 133 C -3.8311 53.4784 0.0 0
M  V30 134 C -6.5601 57.362 0.0 0
M  V30 135 C -6.4551 51.9039 0.0 0
M  V30 136 Si -12.5955 53.7408 0.0 0
M  V30 137 O -11.4934 53.1635 0.0 0
M  V30 138 O -11.7033 54.9479 0.0 0
M  V30 139 O -13.8025 52.8486 0.0 0
M  V30 140 C -14.0125 54.633 0.0 0
M  V30 141 C -10.3912 54.0557 0.0 0
M  V30 142 C -12.9103 56.1549 0.0 0
M  V30 143 C -13.2252 51.7465 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 23 24
M  V30 23 1 23 25
M  V30 24 1 23 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 25 29
M  V30 28 1 26 30
M  V30 29 1 27 31
M  V30 30 1 28 32
M  V30 31 1 29 33
M  V30 32 1 30 34
M  V30 33 1 31 35
M  V30 34 1 35 36
M  V30 35 1 36 37
M  V30 36 1 37 38
M  V30 37 1 38 39
M  V30 38 1 39 40
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 41 44
M  V30 42 1 41 45
M  V30 43 1 42 46
M  V30 44 1 43 47
M  V30 45 1 44 48
M  V30 46 1 45 49
M  V30 47 1 46 50
M  V30 48 1 47 51
M  V30 49 1 48 52
M  V30 50 1 49 53
M  V30 51 1 53 54
M  V30 52 1 54 55
M  V30 53 1 55 56
M  V30 54 1 57 58
M  V30 55 1 57 59
M  V30 56 1 57 60
M  V30 57 1 57 61
M  V30 58 1 58 62
M  V30 59 1 59 63
M  V30 60 1 60 64
M  V30 61 1 61 65
M  V30 62 1 65 66
M  V30 63 1 66 67
M  V30 64 1 67 68
M  V30 65 1 68 69
M  V30 66 1 69 70
M  V30 67 1 70 71
M  V30 68 1 71 72
M  V30 69 1 72 73
M  V30 70 1 73 74
M  V30 71 1 74 75
M  V30 72 1 76 77
M  V30 73 1 76 78
M  V30 74 1 76 79
M  V30 75 1 76 80
M  V30 76 1 77 81
M  V30 77 1 78 82
M  V30 78 1 79 83
M  V30 79 1 80 84
M  V30 80 1 84 85
M  V30 81 1 85 86
M  V30 82 1 86 87
M  V30 83 1 87 88
M  V30 84 1 88 89
M  V30 85 1 89 90
M  V30 86 1 91 92
M  V30 87 1 91 93
M  V30 88 1 91 94
M  V30 89 1 91 95
M  V30 90 1 92 96
M  V30 91 1 93 97
M  V30 92 1 94 98
M  V30 93 1 95 99
M  V30 94 1 99 100
M  V30 95 1 100 101
M  V30 96 1 101 102
M  V30 97 1 102 103
M  V30 98 1 104 105
M  V30 99 1 104 106
M  V30 100 1 104 107
M  V30 101 1 104 108
M  V30 102 1 105 109
M  V30 103 1 106 110
M  V30 104 1 107 111
M  V30 105 1 108 112
M  V30 106 1 109 113
M  V30 107 1 110 114
M  V30 108 1 111 115
M  V30 109 1 116 117
M  V30 110 1 116 118
M  V30 111 1 116 119
M  V30 112 1 116 120
M  V30 113 1 117 121
M  V30 114 1 118 122
M  V30 115 1 119 123
M  V30 116 1 120 124
M  V30 117 1 125 126
M  V30 118 1 125 127
M  V30 119 1 125 128
M  V30 120 1 125 129
M  V30 121 1 126 130
M  V30 122 1 127 131
M  V30 123 1 128 132
M  V30 124 1 130 133
M  V30 125 1 131 134
M  V30 126 1 132 135
M  V30 127 1 136 137
M  V30 128 1 136 138
M  V30 129 1 136 139
M  V30 130 1 136 140
M  V30 131 1 137 141
M  V30 132 1 138 142
M  V30 133 1 139 143
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000743A1-20220106-C00004

>  <Row No>
571

$$$$
US20220000743A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 13 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.757 -1.2893 0.0 0
M  V30 3 N -2.2711 -1.2775 0.0 0
M  V30 4 ? -0.0473 -2.555 0.0 0
M  V30 5 C -3.7853 -1.2657 0.0 0
M  V30 6 C -5.2994 -1.2538 0.0 0
M  V30 7 N -5.3112 -2.7443 0.0 0 CHG=1 CFG=2
M  V30 8 C -4.1047 -3.6197 0.0 0
M  V30 9 C -6.5651 -3.596 0.0 0
M  V30 10 C -6.8017 -2.3185 0.0 0
M  V30 11 N -4.6015 -5.0155 0.0 0
M  V30 12 ? -2.6142 -3.6078 0.0 0
M  V30 13 C -6.1156 -5.0037 0.0 0
M  V30 14 A 1.5141 -2.2711 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 7 10 CFG=1
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 11 13
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 7)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000743A1-20220106-C00005

>  <Row No>
572

$$$$
US20220000744A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 117 107 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 0.844 1.1817 0.0 0
M  V30 3 O -1.1817 -0.9003 0.0 0
M  V30 4 O 1.1254 -0.5627 0.0 0
M  V30 5 C -1.4068 0.9003 0.0 0
M  V30 6 C -0.3376 2.4197 0.0 0
M  V30 7 C -0.6189 -2.0258 0.0 0
M  V30 8 C 2.2509 0.3376 0.0 0
M  V30 9 C -2.8699 0.3376 0.0 0
M  V30 10 C -1.9132 2.1946 0.0 0
M  V30 11 C 0.6189 -1.5193 0.0 0
M  V30 12 C 3.32 -0.225 0.0 0
M  V30 13 N -4.3329 1.2379 0.0 0
M  V30 14 C -5.7398 0.6752 0.0 0
M  V30 15 C -4.5018 2.8699 0.0 0
M  V30 16 Si -2.2509 39.1657 0.0 0
M  V30 17 O -1.1254 38.603 0.0 0
M  V30 18 O -1.4068 40.3474 0.0 0
M  V30 19 O -3.4326 38.3216 0.0 0
M  V30 20 C -3.6577 40.066 0.0 0
M  V30 21 C 0.0 39.5033 0.0 0
M  V30 22 C -2.5885 41.5854 0.0 0
M  V30 23 C -2.8699 37.2524 0.0 0
M  V30 24 C -5.1208 39.5033 0.0 0
M  V30 25 C 1.1254 38.9406 0.0 0
M  V30 26 C -4.1641 41.4166 0.0 0
M  V30 27 C -1.6319 37.7589 0.0 0
M  V30 28 N -6.5838 40.4037 0.0 0
M  V30 29 Si -0.4501 21.1584 0.0 0
M  V30 30 O 0.3939 22.3402 0.0 0
M  V30 31 O -1.6319 20.2581 0.0 0
M  V30 32 O 0.6752 20.5957 0.0 0
M  V30 33 C -1.8569 22.0588 0.0 0
M  V30 34 C -0.7878 23.5782 0.0 0
M  V30 35 C -1.0691 19.1326 0.0 0
M  V30 36 C 1.8007 21.4961 0.0 0
M  V30 37 C -3.32 21.4961 0.0 0
M  V30 38 C -2.3634 23.3531 0.0 0
M  V30 39 C 0.1688 19.6391 0.0 0
M  V30 40 C 2.8699 20.9334 0.0 0
M  V30 41 C -4.7831 22.3964 0.0 0
M  V30 42 N -6.1899 21.8337 0.0 0
M  V30 43 C -7.653 22.7341 0.0 0
M  V30 44 C -6.3588 20.5394 0.0 0
M  V30 45 Si -0.9003 57.6231 0.0 0
M  V30 46 O -0.0562 58.8048 0.0 0
M  V30 47 O -2.082 56.7227 0.0 0
M  V30 48 O 0.225 57.0604 0.0 0
M  V30 49 C -2.3071 58.5235 0.0 0
M  V30 50 C -1.2379 60.0428 0.0 0
M  V30 51 C -1.5193 55.5973 0.0 0
M  V30 52 C 1.3505 57.9607 0.0 0
M  V30 53 C -3.7702 57.9607 0.0 0
M  V30 54 C -2.8136 59.8177 0.0 0
M  V30 55 C -0.2813 56.1037 0.0 0
M  V30 56 C 2.4197 57.398 0.0 0
M  V30 57 C -5.2333 58.8611 0.0 0
M  V30 58 N -6.6401 58.2984 0.0 0
M  V30 59 Si -1.8007 32.413 0.0 0
M  V30 60 O -0.9566 33.651 0.0 0
M  V30 61 O -2.9824 31.5126 0.0 0
M  V30 62 O -0.6752 31.8502 0.0 0
M  V30 63 C -3.2075 33.3133 0.0 0
M  V30 64 C -2.1946 34.8327 0.0 0
M  V30 65 C -2.4197 30.4434 0.0 0
M  V30 66 C 0.4501 32.7506 0.0 0
M  V30 67 C -4.6706 32.7506 0.0 0
M  V30 68 N -6.1337 33.651 0.0 0
M  V30 69 Si 0.4501 14.8559 0.0 0
M  V30 70 O 1.2942 16.0939 0.0 0
M  V30 71 O -0.7315 13.9556 0.0 0
M  V30 72 O 1.5756 14.2932 0.0 0
M  V30 73 C -0.9566 15.7563 0.0 0
M  V30 74 C 0.0562 17.2756 0.0 0
M  V30 75 C -0.1688 12.8864 0.0 0
M  V30 76 C 2.6448 15.1936 0.0 0
M  V30 77 C -2.4197 15.1936 0.0 0
M  V30 78 C -3.8828 16.0939 0.0 0
M  V30 79 N -5.3458 15.5312 0.0 0
M  V30 80 C -6.8089 16.4315 0.0 0
M  V30 81 C -5.5147 14.2369 0.0 0
M  V30 82 Si -0.9003 51.3206 0.0 0
M  V30 83 O -0.0562 52.5586 0.0 0
M  V30 84 O -2.082 50.4202 0.0 0
M  V30 85 O 0.225 50.7578 0.0 0
M  V30 86 C -2.3071 52.2209 0.0 0
M  V30 87 C -1.2942 53.7403 0.0 0
M  V30 88 C -1.5193 49.351 0.0 0
M  V30 89 C 1.2942 51.6582 0.0 0
M  V30 90 C -3.7702 51.6582 0.0 0
M  V30 91 C -5.2333 52.5586 0.0 0
M  V30 92 N -6.6964 51.9958 0.0 0
M  V30 93 Si -2.2509 27.0108 0.0 0
M  V30 94 O -1.4068 28.2488 0.0 0
M  V30 95 O -3.4326 26.1104 0.0 0
M  V30 96 O -1.1254 26.4481 0.0 0
M  V30 97 C -3.6577 27.9112 0.0 0
M  V30 98 C -5.1208 27.3484 0.0 0
M  V30 99 N -6.5838 28.2488 0.0 0
M  V30 100 Si 0.0 8.5534 0.0 0
M  V30 101 O -1.1817 7.7093 0.0 0
M  V30 102 O 0.844 9.7914 0.0 0
M  V30 103 O 1.1254 7.9907 0.0 0
M  V30 104 C -1.463 9.4537 0.0 0
M  V30 105 C -2.9261 8.891 0.0 0
M  V30 106 C -4.3892 9.7914 0.0 0
M  V30 107 N -5.8523 9.2287 0.0 0
M  V30 108 C -7.3154 10.129 0.0 0
M  V30 109 C -6.0211 7.9344 0.0 0
M  V30 110 Si -0.9003 45.4682 0.0 0
M  V30 111 O -2.082 44.6241 0.0 0
M  V30 112 O -0.0562 46.7062 0.0 0
M  V30 113 O 0.225 44.9055 0.0 0
M  V30 114 C -2.3634 46.3686 0.0 0
M  V30 115 C -3.8265 45.8058 0.0 0
M  V30 116 C -5.2896 46.7062 0.0 0
M  V30 117 N -6.7527 46.1435 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 15 1 16 17
M  V30 16 1 16 18
M  V30 17 1 16 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 29 30
M  V30 28 1 29 31
M  V30 29 1 29 32
M  V30 30 1 29 33
M  V30 31 1 30 34
M  V30 32 1 31 35
M  V30 33 1 32 36
M  V30 34 1 33 37
M  V30 35 1 34 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 1 37 41
M  V30 39 1 41 42
M  V30 40 1 42 43
M  V30 41 1 42 44
M  V30 42 1 45 46
M  V30 43 1 45 47
M  V30 44 1 45 48
M  V30 45 1 45 49
M  V30 46 1 46 50
M  V30 47 1 47 51
M  V30 48 1 48 52
M  V30 49 1 49 53
M  V30 50 1 50 54
M  V30 51 1 51 55
M  V30 52 1 52 56
M  V30 53 1 53 57
M  V30 54 1 57 58
M  V30 55 1 59 60
M  V30 56 1 59 61
M  V30 57 1 59 62
M  V30 58 1 59 63
M  V30 59 1 60 64
M  V30 60 1 61 65
M  V30 61 1 62 66
M  V30 62 1 63 67
M  V30 63 1 67 68
M  V30 64 1 69 70
M  V30 65 1 69 71
M  V30 66 1 69 72
M  V30 67 1 69 73
M  V30 68 1 70 74
M  V30 69 1 71 75
M  V30 70 1 72 76
M  V30 71 1 73 77
M  V30 72 1 77 78
M  V30 73 1 78 79
M  V30 74 1 79 80
M  V30 75 1 79 81
M  V30 76 1 82 83
M  V30 77 1 82 84
M  V30 78 1 82 85
M  V30 79 1 82 86
M  V30 80 1 83 87
M  V30 81 1 84 88
M  V30 82 1 85 89
M  V30 83 1 86 90
M  V30 84 1 90 91
M  V30 85 1 91 92
M  V30 86 1 93 94
M  V30 87 1 93 95
M  V30 88 1 93 96
M  V30 89 1 93 97
M  V30 90 1 97 98
M  V30 91 1 98 99
M  V30 92 1 100 101
M  V30 93 1 100 102
M  V30 94 1 100 103
M  V30 95 1 100 104
M  V30 96 1 104 105
M  V30 97 1 105 106
M  V30 98 1 106 107
M  V30 99 1 107 108
M  V30 100 1 107 109
M  V30 101 1 110 111
M  V30 102 1 110 112
M  V30 103 1 110 113
M  V30 104 1 110 114
M  V30 105 1 114 115
M  V30 106 1 115 116
M  V30 107 1 116 117
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000744A1-20220106-C00001

>  <Row No>
573

$$$$
US20220000744A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 19 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0151 1.0867 0.0 0
M  V30 3 O -1.0748 -1.0151 0.0 0
M  V30 4 O 1.2539 -0.7165 0.0 0
M  V30 5 C -1.3136 0.7762 0.0 0
M  V30 6 C -0.0477 2.1854 0.0 0
M  V30 7 C -0.3582 -2.269 0.0 0
M  V30 8 C 2.5078 0.0597 0.0 0
M  V30 9 C -2.6392 0.0477 0.0 0
M  V30 10 N -3.9768 0.824 0.0 0
M  V30 11 C -5.2904 0.0955 0.0 0
M  V30 12 C -4.0245 2.3526 0.0 0
M  V30 13 Si -0.3821 -8.5029 0.0 0
M  V30 14 O 0.6329 -7.4162 0.0 0
M  V30 15 O -1.4569 -9.518 0.0 0
M  V30 16 O 0.8717 -9.2314 0.0 0
M  V30 17 C -1.6958 -7.7267 0.0 0
M  V30 18 C -3.0214 -8.4551 0.0 0
M  V30 19 N -4.3589 -7.6908 0.0 0
M  V30 20 C -5.6726 -8.4193 0.0 0
M  V30 21 C -4.4067 -6.1622 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 10 12
M  V30 12 1 13 14
M  V30 13 1 13 15
M  V30 14 1 13 16
M  V30 15 1 13 17
M  V30 16 1 17 18
M  V30 17 1 18 19
M  V30 18 1 19 20
M  V30 19 1 19 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022002.cdx

>  <name>
US20220000744A1-20220106-C00002

>  <Row No>
574

$$$$
US20220000744A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 183 176 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 0.8828 1.1918 0.0 0
M  V30 3 O 1.1476 -0.6179 0.0 0
M  V30 4 O -1.1476 -0.9269 0.0 0
M  V30 5 C -1.4125 0.8828 0.0 0
M  V30 6 C -0.2648 2.3836 0.0 0
M  V30 7 C 2.4718 -0.4414 0.0 0
M  V30 8 C -1.28 -2.2511 0.0 0
M  V30 9 C -2.825 0.2648 0.0 0
M  V30 10 C 0.6621 3.5312 0.0 0
M  V30 11 C 3.3547 0.7503 0.0 0
M  V30 12 C 0.0 -2.516 0.0 0
M  V30 13 C -4.2375 1.1035 0.0 0
M  V30 14 N -5.65 0.4855 0.0 0
M  V30 15 C -5.7824 -0.8386 0.0 0
M  V30 16 C -7.0625 1.3683 0.0 0
M  V30 17 C -4.5023 -1.1035 0.0 0
M  V30 18 C -8.475 0.7503 0.0 0
M  V30 19 O -4.6347 -2.4277 0.0 0
M  V30 20 C -9.8875 1.6332 0.0 0
M  V30 21 Si -11.3 1.0152 0.0 0
M  V30 22 O -12.1829 2.4277 0.0 0
M  V30 23 O -12.7125 0.3972 0.0 0
M  V30 24 O -10.6821 -0.1324 0.0 0
M  V30 25 C -12.3153 4.0168 0.0 0
M  V30 26 C -14.1251 1.28 0.0 0
M  V30 27 C -9.3578 0.0 0.0 0
M  V30 28 C -10.991 4.1492 0.0 0
M  V30 29 C -15.5376 0.6621 0.0 0
M  V30 30 C -8.7399 -1.1476 0.0 0
M  V30 31 Si -1.0593 19.422 0.0 0
M  V30 32 O -0.1765 20.6138 0.0 0
M  V30 33 O 0.0882 18.804 0.0 0
M  V30 34 O -2.207 18.495 0.0 0
M  V30 35 C -2.4718 20.3048 0.0 0
M  V30 36 C -1.3242 21.8056 0.0 0
M  V30 37 C 1.4125 18.9806 0.0 0
M  V30 38 C -2.3394 17.1708 0.0 0
M  V30 39 C -3.8844 19.6868 0.0 0
M  V30 40 C -0.3972 22.9532 0.0 0
M  V30 41 C 2.2953 20.1724 0.0 0
M  V30 42 C -1.0593 16.9059 0.0 0
M  V30 43 C -5.2969 20.5255 0.0 0
M  V30 44 N -6.7094 19.9075 0.0 0
M  V30 45 C -8.1219 20.7903 0.0 0
M  V30 46 C -6.8418 18.5833 0.0 0
M  V30 47 C -9.5344 20.1724 0.0 0
M  V30 48 C -10.9469 21.0552 0.0 0
M  V30 49 Si -12.3594 20.4372 0.0 0
M  V30 50 O -13.2422 21.8497 0.0 0
M  V30 51 O -13.7719 19.8192 0.0 0
M  V30 52 O -11.7414 19.2895 0.0 0
M  V30 53 C -13.3747 23.4388 0.0 0
M  V30 54 C -15.1844 20.7021 0.0 0
M  V30 55 C -10.4172 19.422 0.0 0
M  V30 56 C -12.0504 23.5712 0.0 0
M  V30 57 C -16.5969 20.0841 0.0 0
M  V30 58 C -9.7992 18.2743 0.0 0
M  V30 59 Si -1.0593 36.3721 0.0 0
M  V30 60 O -0.1765 37.5639 0.0 0
M  V30 61 O 0.0882 35.7541 0.0 0
M  V30 62 O -2.207 35.4451 0.0 0
M  V30 63 C -2.4718 37.2549 0.0 0
M  V30 64 C -1.3242 38.7557 0.0 0
M  V30 65 C 1.4125 35.9307 0.0 0
M  V30 66 C -2.3394 34.1209 0.0 0
M  V30 67 C -3.8844 36.6369 0.0 0
M  V30 68 C -0.3972 39.9034 0.0 0
M  V30 69 C 2.2953 37.1225 0.0 0
M  V30 70 C -1.0593 33.8561 0.0 0
M  V30 71 C -5.2969 37.4756 0.0 0
M  V30 72 N -6.7094 36.8576 0.0 0
M  V30 73 C -8.1219 37.7405 0.0 0
M  V30 74 C -9.5344 37.1225 0.0 0
M  V30 75 C -10.9469 38.0053 0.0 0
M  V30 76 Si -12.3594 37.3873 0.0 0
M  V30 77 O -13.2422 38.7998 0.0 0
M  V30 78 O -13.7719 36.7694 0.0 0
M  V30 79 O -11.7414 36.2397 0.0 0
M  V30 80 C -13.3747 40.3889 0.0 0
M  V30 81 C -15.1844 37.6522 0.0 0
M  V30 82 C -10.4172 36.3721 0.0 0
M  V30 83 C -12.0504 40.5213 0.0 0
M  V30 84 C -16.5969 37.0342 0.0 0
M  V30 85 C -9.7992 35.2244 0.0 0
M  V30 86 Si -2.4718 10.2407 0.0 0
M  V30 87 O -1.5449 11.3883 0.0 0
M  V30 88 O -1.3242 9.6668 0.0 0
M  V30 89 O -3.6636 9.3578 0.0 0
M  V30 90 C -3.8844 11.1235 0.0 0
M  V30 91 C -2.6925 12.5801 0.0 0
M  V30 92 C 0.0 9.7992 0.0 0
M  V30 93 C -3.7961 8.0336 0.0 0
M  V30 94 C -5.2969 10.5055 0.0 0
M  V30 95 C -6.7094 11.3442 0.0 0
M  V30 96 N -8.1219 10.7262 0.0 0
M  V30 97 C -8.2543 9.402 0.0 0
M  V30 98 C -9.5344 11.609 0.0 0
M  V30 99 C -6.9742 9.1371 0.0 0
M  V30 100 C -10.9469 10.991 0.0 0
M  V30 101 O -7.1066 7.8129 0.0 0
M  V30 102 C -12.3594 11.8739 0.0 0
M  V30 103 Si -13.7719 11.2559 0.0 0
M  V30 104 O -15.1844 10.6379 0.0 0
M  V30 105 O -14.6547 12.6684 0.0 0
M  V30 106 O -13.154 10.1082 0.0 0
M  V30 107 C -16.5969 11.5207 0.0 0
M  V30 108 C -14.7872 14.2575 0.0 0
M  V30 109 C -11.8297 10.2407 0.0 0
M  V30 110 Si -2.4718 -7.4156 0.0 0
M  V30 111 O -1.5449 -6.2238 0.0 0
M  V30 112 O -1.3242 -7.9895 0.0 0
M  V30 113 O -3.6636 -8.3426 0.0 0
M  V30 114 C -3.8844 -6.5328 0.0 0
M  V30 115 C -2.6925 -5.032 0.0 0
M  V30 116 C 0.0 -7.857 0.0 0
M  V30 117 C -3.7961 -9.6668 0.0 0
M  V30 118 C -5.2969 -7.1508 0.0 0
M  V30 119 C -6.7094 -6.3121 0.0 0
M  V30 120 N -8.1219 -6.9301 0.0 0
M  V30 121 C -9.5344 -6.0473 0.0 0
M  V30 122 C -8.2543 -8.2543 0.0 0
M  V30 123 C -10.9469 -6.6652 0.0 0
M  V30 124 C -7.1066 -8.8723 0.0 0
M  V30 125 C -12.3594 -5.7824 0.0 0
M  V30 126 C -7.2391 -10.1965 0.0 0
M  V30 127 Si -13.7719 -6.4004 0.0 0
M  V30 128 Si -8.6516 -10.8145 0.0 0
M  V30 129 O -14.6547 -4.9879 0.0 0
M  V30 130 O -15.1844 -7.0184 0.0 0
M  V30 131 O -13.154 -7.5481 0.0 0
M  V30 132 O -10.0641 -9.9317 0.0 0
M  V30 133 O -7.5039 -11.4325 0.0 0
M  V30 134 O -10.0641 -11.4325 0.0 0
M  V30 135 C -14.3899 -3.4429 0.0 0
M  V30 136 C -16.5969 -6.1355 0.0 0
M  V30 137 C -11.8297 -7.4156 0.0 0
M  V30 138 C -10.1965 -8.3426 0.0 0
M  V30 139 C -6.2238 -10.9028 0.0 0
M  V30 140 C -11.4766 -10.5496 0.0 0
M  V30 141 Si -2.4718 27.5439 0.0 0
M  V30 142 O -1.5449 28.6916 0.0 0
M  V30 143 O -1.3242 26.9701 0.0 0
M  V30 144 O -3.6636 26.6611 0.0 0
M  V30 145 C -3.8844 28.4267 0.0 0
M  V30 146 C -2.6925 29.8834 0.0 0
M  V30 147 C 0.0 27.1025 0.0 0
M  V30 148 C -3.7961 25.3369 0.0 0
M  V30 149 C -5.2969 27.8087 0.0 0
M  V30 150 C -6.7094 28.6474 0.0 0
M  V30 151 N -8.1219 28.0295 0.0 0
M  V30 152 C -9.5344 28.9123 0.0 0
M  V30 153 C -8.2543 26.7052 0.0 0
M  V30 154 C -10.9469 28.2943 0.0 0
M  V30 155 C -12.3594 29.1771 0.0 0
M  V30 156 Si -13.7719 28.5591 0.0 0
M  V30 157 O -15.1844 27.9412 0.0 0
M  V30 158 O -14.6547 29.9717 0.0 0
M  V30 159 O -13.154 27.4115 0.0 0
M  V30 160 C -16.5969 28.824 0.0 0
M  V30 161 C -14.7872 31.5607 0.0 0
M  V30 162 C -11.8297 27.5439 0.0 0
M  V30 163 Si -2.4718 45.2003 0.0 0
M  V30 164 O -1.5449 46.3921 0.0 0
M  V30 165 O -1.3242 44.6264 0.0 0
M  V30 166 O -3.6636 44.2733 0.0 0
M  V30 167 C -3.8844 46.0831 0.0 0
M  V30 168 C -2.6925 47.5839 0.0 0
M  V30 169 C 0.0 44.7589 0.0 0
M  V30 170 C -3.7961 42.9491 0.0 0
M  V30 171 C -5.2969 45.4651 0.0 0
M  V30 172 C -6.7094 46.3038 0.0 0
M  V30 173 N -8.1219 45.6858 0.0 0
M  V30 174 C -9.5344 46.5687 0.0 0
M  V30 175 C -10.9469 45.9507 0.0 0
M  V30 176 C -12.3594 46.8335 0.0 0
M  V30 177 Si -13.7719 46.2155 0.0 0
M  V30 178 O -14.6547 47.628 0.0 0
M  V30 179 O -15.1844 45.5975 0.0 0
M  V30 180 O -13.154 45.0679 0.0 0
M  V30 181 C -14.3899 49.173 0.0 0
M  V30 182 C -16.5969 46.4804 0.0 0
M  V30 183 C -11.8297 45.2003 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 47 48
M  V30 47 1 48 49
M  V30 48 1 49 50
M  V30 49 1 49 51
M  V30 50 1 49 52
M  V30 51 1 50 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 59 60
M  V30 58 1 59 61
M  V30 59 1 59 62
M  V30 60 1 59 63
M  V30 61 1 60 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 71 72
M  V30 70 1 72 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 75 76
M  V30 74 1 76 77
M  V30 75 1 76 78
M  V30 76 1 76 79
M  V30 77 1 77 80
M  V30 78 1 78 81
M  V30 79 1 79 82
M  V30 80 1 80 83
M  V30 81 1 81 84
M  V30 82 1 82 85
M  V30 83 1 86 87
M  V30 84 1 86 88
M  V30 85 1 86 89
M  V30 86 1 86 90
M  V30 87 1 87 91
M  V30 88 1 88 92
M  V30 89 1 89 93
M  V30 90 1 90 94
M  V30 91 1 94 95
M  V30 92 1 95 96
M  V30 93 1 96 97
M  V30 94 1 96 98
M  V30 95 1 97 99
M  V30 96 1 98 100
M  V30 97 1 99 101
M  V30 98 1 100 102
M  V30 99 1 102 103
M  V30 100 1 103 104
M  V30 101 1 103 105
M  V30 102 1 103 106
M  V30 103 1 104 107
M  V30 104 1 105 108
M  V30 105 1 106 109
M  V30 106 1 110 111
M  V30 107 1 110 112
M  V30 108 1 110 113
M  V30 109 1 110 114
M  V30 110 1 111 115
M  V30 111 1 112 116
M  V30 112 1 113 117
M  V30 113 1 114 118
M  V30 114 1 118 119
M  V30 115 1 119 120
M  V30 116 1 120 121
M  V30 117 1 120 122
M  V30 118 1 121 123
M  V30 119 1 122 124
M  V30 120 1 123 125
M  V30 121 1 124 126
M  V30 122 1 125 127
M  V30 123 1 126 128
M  V30 124 1 127 129
M  V30 125 1 127 130
M  V30 126 1 127 131
M  V30 127 1 128 132
M  V30 128 1 128 133
M  V30 129 1 128 134
M  V30 130 1 129 135
M  V30 131 1 130 136
M  V30 132 1 131 137
M  V30 133 1 132 138
M  V30 134 1 133 139
M  V30 135 1 134 140
M  V30 136 1 141 142
M  V30 137 1 141 143
M  V30 138 1 141 144
M  V30 139 1 141 145
M  V30 140 1 142 146
M  V30 141 1 143 147
M  V30 142 1 144 148
M  V30 143 1 145 149
M  V30 144 1 149 150
M  V30 145 1 150 151
M  V30 146 1 151 152
M  V30 147 1 151 153
M  V30 148 1 152 154
M  V30 149 1 154 155
M  V30 150 1 155 156
M  V30 151 1 156 157
M  V30 152 1 156 158
M  V30 153 1 156 159
M  V30 154 1 157 160
M  V30 155 1 158 161
M  V30 156 1 159 162
M  V30 157 1 163 164
M  V30 158 1 163 165
M  V30 159 1 163 166
M  V30 160 1 163 167
M  V30 161 1 164 168
M  V30 162 1 165 169
M  V30 163 1 166 170
M  V30 164 1 167 171
M  V30 165 1 171 172
M  V30 166 1 172 173
M  V30 167 1 173 174
M  V30 168 1 174 175
M  V30 169 1 175 176
M  V30 170 1 176 177
M  V30 171 1 177 178
M  V30 172 1 177 179
M  V30 173 1 177 180
M  V30 174 1 178 181
M  V30 175 1 179 182
M  V30 176 1 180 183
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000744A1-20220106-C00003

>  <Row No>
575

$$$$
US20220000744A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 148 143 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.4347 -0.6558 0.0 0
M  V30 3 O -0.9018 1.4347 0.0 0
M  V30 4 O 0.6558 -1.1887 0.0 0
M  V30 5 C 1.1887 0.9018 0.0 0
M  V30 6 C -2.8694 0.2459 0.0 0
M  V30 7 C -0.6148 3.0334 0.0 0
M  V30 8 C 2.0496 -1.0658 0.0 0
M  V30 9 C 2.3775 0.2459 0.0 0
M  V30 10 C -4.3042 -0.4099 0.0 0
M  V30 11 C 0.7788 3.1564 0.0 0
M  V30 12 C 2.7055 -2.2545 0.0 0
M  V30 13 C 3.5663 1.1477 0.0 0
M  V30 14 N 4.7551 0.4919 0.0 0
M  V30 15 C 4.6321 -0.9018 0.0 0
M  V30 16 C 5.9439 1.3937 0.0 0
M  V30 17 C 5.9849 -1.1887 0.0 0
M  V30 18 C 7.1326 0.7788 0.0 0
M  V30 19 C 5.8619 -2.5825 0.0 0
M  V30 20 C 8.3214 1.6806 0.0 0
M  V30 21 Si 9.5102 1.0248 0.0 0
M  V30 22 O 8.3214 0.0819 0.0 0
M  V30 23 O 10.453 2.2135 0.0 0
M  V30 24 O 10.699 0.4099 0.0 0
M  V30 25 C 8.1985 -1.3117 0.0 0
M  V30 26 C 9.2643 3.4433 0.0 0
M  V30 27 C 12.0927 0.5329 0.0 0
M  V30 28 C 9.5512 -1.5987 0.0 0
M  V30 29 C 10.2071 4.6321 0.0 0
M  V30 30 C 13.0356 1.7216 0.0 0
M  V30 31 Si -1.9676 20.9881 0.0 0
M  V30 32 O -3.4023 20.3322 0.0 0
M  V30 33 O -2.8694 22.4229 0.0 0
M  V30 34 O -1.3117 19.7993 0.0 0
M  V30 35 C -0.7788 21.89 0.0 0
M  V30 36 C -4.8371 21.2341 0.0 0
M  V30 37 C -2.5825 24.0216 0.0 0
M  V30 38 C 0.0819 19.9223 0.0 0
M  V30 39 C 0.4099 21.2341 0.0 0
M  V30 40 C -6.2718 20.5782 0.0 0
M  V30 41 C -1.1887 24.1445 0.0 0
M  V30 42 C 0.7378 18.7335 0.0 0
M  V30 43 C 1.5987 22.1359 0.0 0
M  V30 44 N 2.7874 21.48 0.0 0
M  V30 45 C 2.6645 20.0863 0.0 0
M  V30 46 C 3.9762 22.3819 0.0 0
M  V30 47 C 4.0172 19.7993 0.0 0
M  V30 48 C 5.165 21.767 0.0 0
M  V30 49 N 3.8942 18.4056 0.0 0
M  V30 50 C 6.3538 22.6688 0.0 0
M  V30 51 Si 7.5426 22.0129 0.0 0
M  V30 52 O 8.4854 23.2017 0.0 0
M  V30 53 O 8.7314 21.398 0.0 0
M  V30 54 O 6.3538 21.0701 0.0 0
M  V30 55 C 7.2966 24.4315 0.0 0
M  V30 56 C 10.1251 21.521 0.0 0
M  V30 57 C 6.2308 19.6764 0.0 0
M  V30 58 C 8.4854 25.3333 0.0 0
M  V30 59 C 11.0679 22.7098 0.0 0
M  V30 60 C 7.5836 19.3894 0.0 0
M  V30 61 Si -0.9838 41.9763 0.0 0
M  V30 62 O -1.8856 43.411 0.0 0
M  V30 63 O -2.4185 41.3204 0.0 0
M  V30 64 O -0.3279 40.7875 0.0 0
M  V30 65 C 0.2049 42.8781 0.0 0
M  V30 66 C -1.5987 45.0097 0.0 0
M  V30 67 C -3.8532 42.2222 0.0 0
M  V30 68 C -1.5167 39.8447 0.0 0
M  V30 69 C 1.3937 42.2222 0.0 0
M  V30 70 C -0.2049 45.1327 0.0 0
M  V30 71 C -5.452 41.9353 0.0 0
M  V30 72 C -1.2297 38.4919 0.0 0
M  V30 73 C 2.5825 43.1241 0.0 0
M  V30 74 N 3.7713 42.4682 0.0 0
M  V30 75 C 3.6483 41.0745 0.0 0
M  V30 76 C 4.96 43.37 0.0 0
M  V30 77 C 4.8371 40.4186 0.0 0
M  V30 78 C 6.1488 42.7552 0.0 0
M  V30 79 C 4.7141 39.0248 0.0 0
M  V30 80 C 7.3376 43.657 0.0 0
M  V30 81 Si 3.2794 38.369 0.0 0
M  V30 82 Si 8.5264 43.0011 0.0 0
M  V30 83 O 1.8446 39.2708 0.0 0
M  V30 84 O 1.8446 37.7131 0.0 0
M  V30 85 O 4.4681 37.7131 0.0 0
M  V30 86 O 7.3376 42.0583 0.0 0
M  V30 87 O 9.4692 44.1899 0.0 0
M  V30 88 O 9.7152 42.3862 0.0 0
M  V30 89 C 1.7216 40.9105 0.0 0
M  V30 90 C 0.4099 38.6149 0.0 0
M  V30 91 C 5.8209 38.246 0.0 0
M  V30 92 C 7.2146 40.6645 0.0 0
M  V30 93 C 8.2804 45.4197 0.0 0
M  V30 94 C 11.1089 42.5092 0.0 0
M  V30 95 C 0.2869 41.8123 0.0 0
M  V30 96 C -0.7788 37.6721 0.0 0
M  V30 97 C 6.7637 37.3031 0.0 0
M  V30 98 C 8.6084 40.7875 0.0 0
M  V30 99 C 6.6817 45.1327 0.0 0
M  V30 100 C 11.3959 44.1079 0.0 0
M  V30 101 Si 8.1985 11.4779 0.0 0
M  V30 102 O 9.1413 12.6666 0.0 0
M  V30 103 O 9.3872 10.863 0.0 0
M  V30 104 O 7.0097 10.535 0.0 0
M  V30 105 C 6.7637 12.3797 0.0 0
M  V30 106 C 7.9525 13.8964 0.0 0
M  V30 107 C 10.781 10.9859 0.0 0
M  V30 108 C 6.8867 9.1413 0.0 0
M  V30 109 C 5.329 11.7238 0.0 0
M  V30 110 C 3.8942 12.5847 0.0 0
M  V30 111 N 2.4595 11.9288 0.0 0
M  V30 112 C 2.3365 10.535 0.0 0
M  V30 113 C 1.0248 12.8306 0.0 0
M  V30 114 C 3.6893 10.2481 0.0 0
M  V30 115 C -0.4099 12.1747 0.0 0
M  V30 116 C 3.5663 8.8543 0.0 0
M  V30 117 C -1.8446 13.0766 0.0 0
M  V30 118 Si -3.2794 12.4207 0.0 0
M  V30 119 O -4.1812 13.8554 0.0 0
M  V30 120 O -4.7141 11.7648 0.0 0
M  V30 121 O -2.6235 11.2319 0.0 0
M  V30 122 C -3.8942 15.4541 0.0 0
M  V30 123 C -6.1488 12.6666 0.0 0
M  V30 124 C -1.2297 11.3549 0.0 0
M  V30 125 Si 8.1985 29.8425 0.0 0
M  V30 126 O 9.1413 31.0313 0.0 0
M  V30 127 O 9.3872 29.2276 0.0 0
M  V30 128 O 7.0097 28.8997 0.0 0
M  V30 129 C 6.7637 30.7443 0.0 0
M  V30 130 C 7.9525 32.2611 0.0 0
M  V30 131 C 10.781 29.3506 0.0 0
M  V30 132 C 6.8867 27.5059 0.0 0
M  V30 133 C 5.329 30.0885 0.0 0
M  V30 134 C 3.8942 30.9493 0.0 0
M  V30 135 N 2.4595 30.2934 0.0 0
M  V30 136 C 2.3365 28.8997 0.0 0
M  V30 137 C 1.0248 31.1953 0.0 0
M  V30 138 C 3.6893 28.6127 0.0 0
M  V30 139 C -0.4099 30.5394 0.0 0
M  V30 140 N 3.5663 27.219 0.0 0
M  V30 141 C -1.8446 31.4412 0.0 0
M  V30 142 Si -3.2794 30.7853 0.0 0
M  V30 143 O -4.1812 32.2201 0.0 0
M  V30 144 O -4.7141 30.1295 0.0 0
M  V30 145 O -2.6235 29.5966 0.0 0
M  V30 146 C -3.8942 33.8188 0.0 0
M  V30 147 C -6.1488 31.0313 0.0 0
M  V30 148 C -1.2297 29.7195 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 46 48
M  V30 47 1 47 49
M  V30 48 1 48 50
M  V30 49 1 50 51
M  V30 50 1 51 52
M  V30 51 1 51 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 56 59
M  V30 58 1 57 60
M  V30 59 1 61 62
M  V30 60 1 61 63
M  V30 61 1 61 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 68 72
M  V30 70 1 69 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 74 76
M  V30 74 1 75 77
M  V30 75 1 76 78
M  V30 76 1 77 79
M  V30 77 1 78 80
M  V30 78 1 79 81
M  V30 79 1 80 82
M  V30 80 1 81 83
M  V30 81 1 81 84
M  V30 82 1 81 85
M  V30 83 1 82 86
M  V30 84 1 82 87
M  V30 85 1 82 88
M  V30 86 1 83 89
M  V30 87 1 84 90
M  V30 88 1 85 91
M  V30 89 1 86 92
M  V30 90 1 87 93
M  V30 91 1 88 94
M  V30 92 1 89 95
M  V30 93 1 90 96
M  V30 94 1 91 97
M  V30 95 1 92 98
M  V30 96 1 93 99
M  V30 97 1 94 100
M  V30 98 1 101 102
M  V30 99 1 101 103
M  V30 100 1 101 104
M  V30 101 1 101 105
M  V30 102 1 102 106
M  V30 103 1 103 107
M  V30 104 1 104 108
M  V30 105 1 105 109
M  V30 106 1 109 110
M  V30 107 1 110 111
M  V30 108 1 111 112
M  V30 109 1 111 113
M  V30 110 1 112 114
M  V30 111 1 113 115
M  V30 112 2 114 116
M  V30 113 1 115 117
M  V30 114 1 117 118
M  V30 115 1 118 119
M  V30 116 1 118 120
M  V30 117 1 118 121
M  V30 118 1 119 122
M  V30 119 1 120 123
M  V30 120 1 121 124
M  V30 121 1 125 126
M  V30 122 1 125 127
M  V30 123 1 125 128
M  V30 124 1 125 129
M  V30 125 1 126 130
M  V30 126 1 127 131
M  V30 127 1 128 132
M  V30 128 1 129 133
M  V30 129 1 133 134
M  V30 130 1 134 135
M  V30 131 1 135 136
M  V30 132 1 135 137
M  V30 133 1 136 138
M  V30 134 1 137 139
M  V30 135 1 138 140
M  V30 136 1 139 141
M  V30 137 1 141 142
M  V30 138 1 142 143
M  V30 139 1 142 144
M  V30 140 1 142 145
M  V30 141 1 143 146
M  V30 142 1 144 147
M  V30 143 1 145 148
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023002.cdx

>  <name>
US20220000744A1-20220106-C00004

>  <Row No>
576

$$$$
US20220000744A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 143 133 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.2168 -0.885 0.0 0
M  V30 3 O 0.885 1.2168 0.0 0
M  V30 4 O 1.1062 -0.5531 0.0 0
M  V30 5 C -1.4381 0.9403 0.0 0
M  V30 6 C -0.6084 -1.9912 0.0 0
M  V30 7 C -0.3318 2.4337 0.0 0
M  V30 8 C 2.2125 0.3318 0.0 0
M  V30 9 C -2.8762 0.3871 0.0 0
M  V30 10 C 0.6084 -1.4381 0.0 0
M  V30 11 C 0.5531 3.6506 0.0 0
M  V30 12 C 3.3187 -0.2212 0.0 0
M  V30 13 C -4.3143 1.2721 0.0 0
M  V30 14 C -5.7525 0.719 0.0 0
M  V30 15 C -7.1906 1.604 0.0 0
M  V30 16 C -8.6287 1.0509 0.0 0
M  V30 17 C -10.0669 1.9359 0.0 0
M  V30 18 C -11.505 1.3828 0.0 0
M  V30 19 C -12.9431 2.2678 0.0 0
M  V30 20 C -14.3813 1.7146 0.0 0
M  V30 21 C -15.8194 2.5996 0.0 0
M  V30 22 C -17.2575 2.0465 0.0 0
M  V30 23 Si -4.8675 18.585 0.0 0
M  V30 24 O -6.0844 17.7 0.0 0
M  V30 25 O -3.9825 19.8019 0.0 0
M  V30 26 O -3.7612 18.0319 0.0 0
M  V30 27 C -6.3056 19.5253 0.0 0
M  V30 28 C -5.4759 16.5938 0.0 0
M  V30 29 C -5.1993 21.0188 0.0 0
M  V30 30 C -2.655 18.9169 0.0 0
M  V30 31 C -7.7437 18.9722 0.0 0
M  V30 32 C -4.259 17.1469 0.0 0
M  V30 33 C -4.3143 22.2357 0.0 0
M  V30 34 C -1.5487 18.3638 0.0 0
M  V30 35 C -9.1819 19.8572 0.0 0
M  V30 36 C -10.62 19.3041 0.0 0
M  V30 37 C -12.0581 20.1891 0.0 0
M  V30 38 C -13.4963 19.636 0.0 0
M  V30 39 C -14.9344 20.521 0.0 0
M  V30 40 C -16.3725 19.9678 0.0 0
M  V30 41 Si -7.5225 32.7451 0.0 0
M  V30 42 O -8.7394 31.8601 0.0 0
M  V30 43 O -6.6375 33.962 0.0 0
M  V30 44 O -6.4162 32.192 0.0 0
M  V30 45 C -8.9606 33.6854 0.0 0
M  V30 46 C -8.1309 30.7538 0.0 0
M  V30 47 C -7.8544 35.1788 0.0 0
M  V30 48 C -5.31 33.077 0.0 0
M  V30 49 C -10.3987 33.1323 0.0 0
M  V30 50 C -6.914 31.307 0.0 0
M  V30 51 C -6.9694 36.3957 0.0 0
M  V30 52 C -4.2037 32.5238 0.0 0
M  V30 53 C -11.8369 34.0173 0.0 0
M  V30 54 C -13.275 33.4642 0.0 0
M  V30 55 C -14.7131 34.3492 0.0 0
M  V30 56 C -16.1513 33.796 0.0 0
M  V30 57 Si -2.2125 10.1775 0.0 0
M  V30 58 O -1.1615 9.6244 0.0 0
M  V30 59 O -1.3828 11.3391 0.0 0
M  V30 60 O -3.374 9.3478 0.0 0
M  V30 61 C -3.5953 11.0625 0.0 0
M  V30 62 C -0.1106 10.5094 0.0 0
M  V30 63 C -2.5443 12.5006 0.0 0
M  V30 64 C -2.8209 8.2969 0.0 0
M  V30 65 C -4.9781 10.5647 0.0 0
M  V30 66 C -6.3609 11.4497 0.0 0
M  V30 67 C -7.7437 10.8966 0.0 0
M  V30 68 C -9.1266 11.7816 0.0 0
M  V30 69 C -10.5094 11.2284 0.0 0
M  V30 70 C -11.8922 12.1134 0.0 0
M  V30 71 C -13.275 11.5603 0.0 0
M  V30 72 C -14.6578 12.4453 0.0 0
M  V30 73 C -16.0406 11.8922 0.0 0
M  V30 74 C -17.4235 12.7772 0.0 0
M  V30 75 C -18.8063 12.2241 0.0 0
M  V30 76 Si -4.8675 26.1076 0.0 0
M  V30 77 O -3.7612 25.5544 0.0 0
M  V30 78 O -3.9825 27.3244 0.0 0
M  V30 79 O -6.0844 25.2226 0.0 0
M  V30 80 C -6.3056 27.0479 0.0 0
M  V30 81 C -2.655 26.4394 0.0 0
M  V30 82 C -5.1993 28.5413 0.0 0
M  V30 83 C -5.4759 24.1163 0.0 0
M  V30 84 C -7.7437 26.4947 0.0 0
M  V30 85 C -9.1819 27.3798 0.0 0
M  V30 86 C -10.62 26.8266 0.0 0
M  V30 87 C -12.0581 27.7116 0.0 0
M  V30 88 C -13.4963 27.1585 0.0 0
M  V30 89 C -14.9344 28.0435 0.0 0
M  V30 90 C -16.3725 27.4904 0.0 0
M  V30 91 Si -7.5225 41.1526 0.0 0
M  V30 92 O -6.4162 40.5995 0.0 0
M  V30 93 O -6.6375 42.3695 0.0 0
M  V30 94 O -8.7394 40.2676 0.0 0
M  V30 95 C -8.9606 42.0929 0.0 0
M  V30 96 C -5.31 41.4845 0.0 0
M  V30 97 C -7.8544 43.5864 0.0 0
M  V30 98 C -8.1309 39.1614 0.0 0
M  V30 99 C -10.3987 41.5398 0.0 0
M  V30 100 C -11.8369 42.4248 0.0 0
M  V30 101 C -13.275 41.8717 0.0 0
M  V30 102 C -14.7131 42.7567 0.0 0
M  V30 103 C -16.1513 42.2036 0.0 0
M  V30 104 Si -5.31 48.2327 0.0 0
M  V30 105 O -4.425 49.4495 0.0 0
M  V30 106 O -6.5269 47.3477 0.0 0
M  V30 107 O -4.2037 47.6795 0.0 0
M  V30 108 C -6.7481 49.1177 0.0 0
M  V30 109 C -5.5865 50.6664 0.0 0
M  V30 110 C -5.9737 46.2414 0.0 0
M  V30 111 C -3.0975 48.5645 0.0 0
M  V30 112 C -8.1862 48.5645 0.0 0
M  V30 113 C -4.7015 51.828 0.0 0
M  V30 114 C -4.7015 46.4073 0.0 0
M  V30 115 C -1.9912 48.0114 0.0 0
M  V30 116 Si -12.39 48.2327 0.0 0
M  V30 117 O -11.2837 47.6795 0.0 0
M  V30 118 O -11.505 49.4495 0.0 0
M  V30 119 O -13.6069 47.3477 0.0 0
M  V30 120 C -13.8281 49.173 0.0 0
M  V30 121 C -10.1775 48.5645 0.0 0
M  V30 122 C -12.7219 50.6664 0.0 0
M  V30 123 C -12.9984 46.2414 0.0 0
M  V30 124 C -15.2663 48.6198 0.0 0
M  V30 125 Si -5.7525 56.6402 0.0 0
M  V30 126 O -4.8675 57.8571 0.0 0
M  V30 127 O -6.9694 55.7552 0.0 0
M  V30 128 O -4.6462 56.0871 0.0 0
M  V30 129 C -7.1906 57.5252 0.0 0
M  V30 130 C -6.029 59.074 0.0 0
M  V30 131 C -6.3609 54.6489 0.0 0
M  V30 132 C -3.54 56.9721 0.0 0
M  V30 133 C -5.144 60.2355 0.0 0
M  V30 134 C -5.0887 54.8149 0.0 0
M  V30 135 C -2.4337 56.4189 0.0 0
M  V30 136 Si -12.8325 56.6402 0.0 0
M  V30 137 O -11.9475 57.8571 0.0 0
M  V30 138 O -14.0494 55.7552 0.0 0
M  V30 139 O -11.7262 56.0871 0.0 0
M  V30 140 C -14.2706 57.5252 0.0 0
M  V30 141 C -13.1644 59.074 0.0 0
M  V30 142 C -13.4963 54.6489 0.0 0
M  V30 143 C -10.62 56.9721 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 23 24
M  V30 23 1 23 25
M  V30 24 1 23 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 25 29
M  V30 28 1 26 30
M  V30 29 1 27 31
M  V30 30 1 28 32
M  V30 31 1 29 33
M  V30 32 1 30 34
M  V30 33 1 31 35
M  V30 34 1 35 36
M  V30 35 1 36 37
M  V30 36 1 37 38
M  V30 37 1 38 39
M  V30 38 1 39 40
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 41 44
M  V30 42 1 41 45
M  V30 43 1 42 46
M  V30 44 1 43 47
M  V30 45 1 44 48
M  V30 46 1 45 49
M  V30 47 1 46 50
M  V30 48 1 47 51
M  V30 49 1 48 52
M  V30 50 1 49 53
M  V30 51 1 53 54
M  V30 52 1 54 55
M  V30 53 1 55 56
M  V30 54 1 57 58
M  V30 55 1 57 59
M  V30 56 1 57 60
M  V30 57 1 57 61
M  V30 58 1 58 62
M  V30 59 1 59 63
M  V30 60 1 60 64
M  V30 61 1 61 65
M  V30 62 1 65 66
M  V30 63 1 66 67
M  V30 64 1 67 68
M  V30 65 1 68 69
M  V30 66 1 69 70
M  V30 67 1 70 71
M  V30 68 1 71 72
M  V30 69 1 72 73
M  V30 70 1 73 74
M  V30 71 1 74 75
M  V30 72 1 76 77
M  V30 73 1 76 78
M  V30 74 1 76 79
M  V30 75 1 76 80
M  V30 76 1 77 81
M  V30 77 1 78 82
M  V30 78 1 79 83
M  V30 79 1 80 84
M  V30 80 1 84 85
M  V30 81 1 85 86
M  V30 82 1 86 87
M  V30 83 1 87 88
M  V30 84 1 88 89
M  V30 85 1 89 90
M  V30 86 1 91 92
M  V30 87 1 91 93
M  V30 88 1 91 94
M  V30 89 1 91 95
M  V30 90 1 92 96
M  V30 91 1 93 97
M  V30 92 1 94 98
M  V30 93 1 95 99
M  V30 94 1 99 100
M  V30 95 1 100 101
M  V30 96 1 101 102
M  V30 97 1 102 103
M  V30 98 1 104 105
M  V30 99 1 104 106
M  V30 100 1 104 107
M  V30 101 1 104 108
M  V30 102 1 105 109
M  V30 103 1 106 110
M  V30 104 1 107 111
M  V30 105 1 108 112
M  V30 106 1 109 113
M  V30 107 1 110 114
M  V30 108 1 111 115
M  V30 109 1 116 117
M  V30 110 1 116 118
M  V30 111 1 116 119
M  V30 112 1 116 120
M  V30 113 1 117 121
M  V30 114 1 118 122
M  V30 115 1 119 123
M  V30 116 1 120 124
M  V30 117 1 125 126
M  V30 118 1 125 127
M  V30 119 1 125 128
M  V30 120 1 125 129
M  V30 121 1 126 130
M  V30 122 1 127 131
M  V30 123 1 128 132
M  V30 124 1 130 133
M  V30 125 1 131 134
M  V30 126 1 132 135
M  V30 127 1 136 137
M  V30 128 1 136 138
M  V30 129 1 136 139
M  V30 130 1 136 140
M  V30 131 1 137 141
M  V30 132 1 138 142
M  V30 133 1 139 143
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000744A1-20220106-C00005

>  <Row No>
577

$$$$
US20220000744A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=16
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000744A1-20220106-C00007

>  <Row No>
578

$$$$
US20220000744A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 13 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.7802 -1.2886 0.0 0
M  V30 3 N -2.2935 -1.2768 0.0 0
M  V30 4 ? -0.0591 -2.5536 0.0 0
M  V30 5 C -3.8068 -1.265 0.0 0
M  V30 6 C -5.3201 -1.2531 0.0 0
M  V30 7 N -5.332 -2.7428 0.0 0 CHG=1 CFG=2
M  V30 8 C -4.1024 -3.5822 0.0 0
M  V30 9 C -6.5615 -3.6177 0.0 0
M  V30 10 C -6.8216 -2.3172 0.0 0
M  V30 11 N -4.5635 -4.9891 0.0 0
M  V30 12 ? -2.6127 -3.5704 0.0 0
M  V30 13 C -6.0768 -5.0127 0.0 0
M  V30 14 A 1.8916 -2.932 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 7 10 CFG=1
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 11 13
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 7)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000744A1-20220106-C00009

>  <Row No>
579

$$$$
US20220000744A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=16
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000744A1-20220106-C00011

>  <Row No>
580

$$$$
US20220000745A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 13 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0271 1.0972 0.0 0
M  V30 3 O -1.0855 -1.0271 0.0 0
M  V30 4 O 1.2606 -0.7236 0.0 0
M  V30 5 C -1.3189 0.7937 0.0 0
M  V30 6 C -0.0466 2.206 0.0 0
M  V30 7 C -0.3501 -2.2877 0.0 0
M  V30 8 C 2.5212 0.0466 0.0 0
M  V30 9 C -2.6496 0.0583 0.0 0
M  V30 10 C -1.5407 1.8675 0.0 0
M  V30 11 C 1.0738 -1.8792 0.0 0
M  V30 12 C 3.7701 -0.6769 0.0 0
M  V30 13 C -3.9919 0.817 0.0 0
M  V30 14 N -5.3109 0.0817 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000745A1-20220106-C00001

>  <Row No>
581

$$$$
US20220000745A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0264 1.0892 0.0 0
M  V30 3 O -1.0787 -1.0264 0.0 0
M  V30 4 O 1.2673 -0.7122 0.0 0
M  V30 5 C -1.3196 0.796 0.0 0
M  V30 6 C -0.0418 2.1994 0.0 0
M  V30 7 C -0.3561 -2.2832 0.0 0
M  V30 8 C 2.5346 0.0628 0.0 0
M  V30 9 C -2.6393 0.0733 0.0 0
M  V30 10 C -3.98 0.8274 0.0 0
M  V30 11 N -5.2892 0.0942 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000745A1-20220106-C00002

>  <Row No>
582

$$$$
US20220000745A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 7 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.024 1.0867 0.0 0
M  V30 3 O -1.0763 -1.024 0.0 0
M  V30 4 O 1.2644 -0.7105 0.0 0
M  V30 5 C -1.3166 0.7941 0.0 0
M  V30 6 C -2.6333 0.0731 0.0 0
M  V30 7 C -3.9709 0.8255 0.0 0
M  V30 8 N -5.2771 0.094 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000745A1-20220106-C00003

>  <Row No>
583

$$$$
US20220000745A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.028 1.0981 0.0 0
M  V30 3 O -1.0864 -1.028 0.0 0
M  V30 4 O 1.2617 -0.7243 0.0 0
M  V30 5 C -1.3201 0.7944 0.0 0
M  V30 6 C -0.0467 2.208 0.0 0
M  V30 7 C -0.3504 -2.2897 0.0 0
M  V30 8 C 2.5234 0.0467 0.0 0
M  V30 9 C -2.6519 0.07 0.0 0
M  V30 10 C -1.542 1.8692 0.0 0
M  V30 11 C 1.0747 -1.8808 0.0 0
M  V30 12 C 3.7734 -0.6775 0.0 0
M  V30 13 N -3.9954 0.8294 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000745A1-20220106-C00004

>  <Row No>
584

$$$$
US20220000745A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.267 -0.7062 0.0 0
M  V30 3 O 1.0281 1.08 0.0 0
M  V30 4 O -1.0904 -1.0281 0.0 0
M  V30 5 C -1.3293 0.7685 0.0 0
M  V30 6 C 2.534 0.0623 0.0 0
M  V30 7 C -0.0623 2.1705 0.0 0
M  V30 8 C -0.0623 -2.0562 0.0 0
M  V30 9 C -2.6586 0.0623 0.0 0
M  V30 10 C -3.9879 0.8308 0.0 0
M  V30 11 N -5.3172 0.1246 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000745A1-20220106-C00005

>  <Row No>
585

$$$$
US20220000745A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 7 6 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2646 -0.7048 0.0 0
M  V30 3 O 1.0262 1.078 0.0 0
M  V30 4 O -1.0884 -1.0262 0.0 0
M  V30 5 C -1.3268 0.767 0.0 0
M  V30 6 C -2.6537 0.0621 0.0 0
M  V30 7 N -3.9805 0.8292 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000745A1-20220106-C00006

>  <Row No>
586

$$$$
US20220000745A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 15 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0275 1.0852 0.0 0
M  V30 3 O -1.0968 -1.0275 0.0 0
M  V30 4 O 1.2584 -0.7042 0.0 0
M  V30 5 C -1.3277 0.7966 0.0 0
M  V30 6 C -0.0692 2.1821 0.0 0
M  V30 7 C -0.0692 -2.0551 0.0 0
M  V30 8 C 2.5169 0.0923 0.0 0
M  V30 9 C -2.6554 0.0692 0.0 0
M  V30 10 C -1.5471 1.8357 0.0 0
M  V30 11 C 1.1891 -1.2584 0.0 0
M  V30 12 C 3.7753 -0.6119 0.0 0
M  V30 13 C -3.9832 0.8659 0.0 0
M  V30 14 N -5.3109 0.1616 0.0 0
M  V30 15 C -6.6386 0.9582 0.0 0
M  V30 16 C -5.3455 -1.293 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000745A1-20220106-C00007

>  <Row No>
587

$$$$
US20220000745A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2545 -0.702 0.0 0
M  V30 3 O 1.0243 1.0819 0.0 0
M  V30 4 O -1.0934 -1.0243 0.0 0
M  V30 5 C -1.3236 0.7941 0.0 0
M  V30 6 C 2.5091 0.092 0.0 0
M  V30 7 C -0.069 2.1753 0.0 0
M  V30 8 C -0.069 -2.0487 0.0 0
M  V30 9 C -2.6472 0.069 0.0 0
M  V30 10 C -3.9708 0.8632 0.0 0
M  V30 11 N -5.2944 0.1496 0.0 0
M  V30 12 C -6.618 0.9437 0.0 0
M  V30 13 C -5.3289 -1.3005 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000745A1-20220106-C00008

>  <Row No>
588

$$$$
US20220000745A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 9 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2521 -0.7237 0.0 0
M  V30 3 O 1.0223 1.0798 0.0 0
M  V30 4 O -1.0913 -1.0223 0.0 0
M  V30 5 C -1.321 0.7926 0.0 0
M  V30 6 C -2.6421 0.0918 0.0 0
M  V30 7 C -3.9631 0.8845 0.0 0
M  V30 8 N -5.2842 0.1608 0.0 0
M  V30 9 C -6.6052 0.9534 0.0 0
M  V30 10 C -5.3186 -1.2865 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 8 10
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000745A1-20220106-C00009

>  <Row No>
589

$$$$
US20220000745A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 14 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0189 1.0788 0.0 0
M  V30 3 O -1.0908 -1.0189 0.0 0
M  V30 4 O 1.2586 -0.7192 0.0 0
M  V30 5 C -1.3306 0.7791 0.0 0
M  V30 6 C -0.0719 2.1697 0.0 0
M  V30 7 C -0.0719 -2.0378 0.0 0
M  V30 8 C 2.5173 0.0599 0.0 0
M  V30 9 C -2.6612 0.0599 0.0 0
M  V30 10 C -1.5583 1.8101 0.0 0
M  V30 11 C 1.1867 -1.2466 0.0 0
M  V30 12 C 3.776 -0.6593 0.0 0
M  V30 13 N -3.9918 0.8391 0.0 0
M  V30 14 C -5.3224 0.1198 0.0 0
M  V30 15 C -4.0277 2.3735 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000745A1-20220106-C00010

>  <Row No>
590

$$$$
US20220000745A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.0894 -1.0175 0.0 0
M  V30 3 O 1.0175 1.0774 0.0 0
M  V30 4 O 1.257 -0.7182 0.0 0
M  V30 5 C -1.3288 0.7661 0.0 0
M  V30 6 C -0.0718 -2.0351 0.0 0
M  V30 7 C -0.0718 2.1668 0.0 0
M  V30 8 C 2.514 0.0478 0.0 0
M  V30 9 C -2.6576 0.0478 0.0 0
M  V30 10 N -3.9865 0.826 0.0 0
M  V30 11 C -5.3153 0.1077 0.0 0
M  V30 12 C -4.0224 2.3583 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 10 12
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000745A1-20220106-C00011

>  <Row No>
591

$$$$
US20220000745A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2513 -0.7269 0.0 0
M  V30 3 O 1.013 1.0725 0.0 0
M  V30 4 O -1.0845 -1.013 0.0 0
M  V30 5 C -1.3228 0.7627 0.0 0
M  V30 6 C -2.6457 0.0476 0.0 0
M  V30 7 N -3.9686 0.8223 0.0 0
M  V30 8 C -5.2914 0.1072 0.0 0
M  V30 9 C -4.0043 2.3477 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000745A1-20220106-C00012

>  <Row No>
592

$$$$
US20220000745A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 20 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 0.7035 -1.278 0.0 0
M  V30 3 O -0.7856 1.3484 0.0 0
M  V30 4 O -1.3484 -0.7035 0.0 0
M  V30 5 C 1.278 0.7856 0.0 0
M  V30 6 C 2.1809 -1.2429 0.0 0
M  V30 7 C -0.4338 2.8493 0.0 0
M  V30 8 C -2.6968 0.082 0.0 0
M  V30 9 C 2.5561 0.082 0.0 0
M  V30 10 C 3.8342 0.8676 0.0 0
M  V30 11 N 5.1123 0.1641 0.0 0
M  V30 12 C 6.3904 0.9497 0.0 0
M  V30 13 C 7.6685 0.2462 0.0 0
M  V30 14 C 8.9466 1.0318 0.0 0
M  V30 15 Si 10.2247 0.3283 0.0 0
M  V30 16 O 11.5028 -0.3752 0.0 0
M  V30 17 O 11.2683 1.4422 0.0 0
M  V30 18 O 9.1108 -0.7152 0.0 0
M  V30 19 C 12.9802 -0.34 0.0 0
M  V30 20 C 10.1544 2.5561 0.0 0
M  V30 21 C 9.0756 -2.1926 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000745A1-20220106-C00013

>  <Row No>
593

$$$$
US20220000745A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.0998 -1.0303 0.0 0
M  V30 3 O 1.2618 -0.6946 0.0 0
M  V30 4 O 1.0303 1.0998 0.0 0
M  V30 5 C -1.3313 0.7756 0.0 0
M  V30 6 C -1.1345 -2.489 0.0 0
M  V30 7 C 2.7205 -0.6598 0.0 0
M  V30 8 C -0.0694 2.1996 0.0 0
M  V30 9 C -2.6627 0.081 0.0 0
M  V30 10 C 0.2778 -2.8363 0.0 0
M  V30 11 C 3.7509 0.4399 0.0 0
M  V30 12 C 0.9608 3.2994 0.0 0
M  V30 13 C -3.994 0.8566 0.0 0
M  V30 14 N -5.3254 0.162 0.0 0
M  V30 15 C -6.6567 0.9377 0.0 0
M  V30 16 C -7.9881 0.2431 0.0 0
M  V30 17 C -9.3194 1.0187 0.0 0
M  V30 18 Si -10.6508 0.3241 0.0 0
M  V30 19 O -11.4496 1.6555 0.0 0
M  V30 20 O -9.9562 -0.9377 0.0 0
M  V30 21 O -11.9821 -0.3704 0.0 0
M  V30 22 C -11.1023 3.1373 0.0 0
M  V30 23 C -8.4975 -0.903 0.0 0
M  V30 24 C -13.3135 0.4051 0.0 0
M  V30 25 C -9.6436 3.172 0.0 0
M  V30 26 C -7.7681 -2.1648 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000745A1-20220106-C00014

>  <Row No>
594

$$$$
US20220000745A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 0.7032 -1.2775 0.0 0
M  V30 3 O -0.7969 1.3478 0.0 0
M  V30 4 O -1.3478 -0.7032 0.0 0
M  V30 5 C 1.2775 0.7969 0.0 0
M  V30 6 C 2.1799 -1.2423 0.0 0
M  V30 7 C -0.4453 2.848 0.0 0
M  V30 8 C -2.6956 0.0937 0.0 0
M  V30 9 C 2.555 0.0937 0.0 0
M  V30 10 C 3.8325 0.8907 0.0 0
M  V30 11 N 5.11 0.1875 0.0 0
M  V30 12 C 6.3875 0.9845 0.0 0
M  V30 13 C 5.0748 -1.2892 0.0 0
M  V30 14 C 7.665 0.2812 0.0 0
M  V30 15 C 8.9425 1.0782 0.0 0
M  V30 16 Si 10.22 0.375 0.0 0
M  V30 17 O 11.4975 -0.3281 0.0 0
M  V30 18 O 11.2631 1.4884 0.0 0
M  V30 19 O 9.1066 -0.668 0.0 0
M  V30 20 C 12.9743 -0.293 0.0 0
M  V30 21 C 10.1497 2.6019 0.0 0
M  V30 22 C 9.0714 -2.1448 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00035001.cdx

>  <name>
US20220000745A1-20220106-C00015

>  <Row No>
595

$$$$
US20220000745A1-20220106-C00016
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.1004 -1.0309 0.0 0
M  V30 3 O 1.2626 -0.695 0.0 0
M  V30 4 O 1.0309 1.1004 0.0 0
M  V30 5 C -1.3321 0.7877 0.0 0
M  V30 6 C -1.1352 -2.4905 0.0 0
M  V30 7 C 2.7222 -0.6602 0.0 0
M  V30 8 C -0.0695 2.2009 0.0 0
M  V30 9 C -2.6642 0.0926 0.0 0
M  V30 10 C 0.278 -2.838 0.0 0
M  V30 11 C 3.7531 0.4401 0.0 0
M  V30 12 C 0.9614 3.3014 0.0 0
M  V30 13 C -3.9964 0.8803 0.0 0
M  V30 14 N -5.3285 0.1853 0.0 0
M  V30 15 C -6.6607 0.973 0.0 0
M  V30 16 C -5.3633 -1.2742 0.0 0
M  V30 17 C -7.9928 0.278 0.0 0
M  V30 18 C -9.325 1.0657 0.0 0
M  V30 19 Si -10.6571 0.3706 0.0 0
M  V30 20 O -11.4564 1.7028 0.0 0
M  V30 21 O -9.9621 -0.8919 0.0 0
M  V30 22 O -11.9893 -0.3243 0.0 0
M  V30 23 C -11.1089 3.1855 0.0 0
M  V30 24 C -8.5025 -0.8572 0.0 0
M  V30 25 C -13.3214 0.4517 0.0 0
M  V30 26 C -9.6493 3.2203 0.0 0
M  V30 27 C -7.7843 -2.1198 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 19 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000745A1-20220106-C00016

>  <Row No>
596

$$$$
US20220000745A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 0.7045 -1.2799 0.0 0
M  V30 3 O -0.7984 1.3503 0.0 0
M  V30 4 O -1.3503 -0.7045 0.0 0
M  V30 5 C 1.2799 0.7984 0.0 0
M  V30 6 C 2.184 -1.2446 0.0 0
M  V30 7 C -0.4462 2.8533 0.0 0
M  V30 8 C -2.7007 0.0821 0.0 0
M  V30 9 C 2.5598 0.0939 0.0 0
M  V30 10 C 3.8397 0.8924 0.0 0
M  V30 11 N 5.1196 0.1878 0.0 0
M  V30 12 C 5.0844 -1.2916 0.0 0
M  V30 13 C 6.3995 0.9863 0.0 0
M  V30 14 C 6.3643 -2.0079 0.0 0
M  V30 15 C 7.6794 0.2818 0.0 0
M  V30 16 O 6.3291 -3.4874 0.0 0
M  V30 17 C 8.9593 1.0802 0.0 0
M  V30 18 Si 10.2393 0.3757 0.0 0
M  V30 19 O 11.5192 -0.3287 0.0 0
M  V30 20 O 11.2843 1.4912 0.0 0
M  V30 21 O 9.1237 -0.6693 0.0 0
M  V30 22 C 12.9987 -0.2935 0.0 0
M  V30 23 C 10.1688 2.6067 0.0 0
M  V30 24 C 9.0885 -2.1488 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000745A1-20220106-C00017

>  <Row No>
597

$$$$
US20220000745A1-20220106-C00018
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.103 -1.0334 0.0 0
M  V30 3 O 1.2656 -0.6966 0.0 0
M  V30 4 O 1.0334 1.103 0.0 0
M  V30 5 C -1.3352 0.7779 0.0 0
M  V30 6 C -1.1379 -2.4964 0.0 0
M  V30 7 C 2.7286 -0.6618 0.0 0
M  V30 8 C -0.0696 2.2061 0.0 0
M  V30 9 C -2.6705 0.0812 0.0 0
M  V30 10 C 0.2786 -2.8447 0.0 0
M  V30 11 C 3.762 0.4412 0.0 0
M  V30 12 C 0.9637 3.3092 0.0 0
M  V30 13 C -4.0058 0.8708 0.0 0
M  V30 14 N -5.3411 0.1741 0.0 0
M  V30 15 C -5.376 -1.2888 0.0 0
M  V30 16 C -6.6764 0.9637 0.0 0
M  V30 17 C -4.1103 -2.0087 0.0 0
M  V30 18 C -8.0117 0.267 0.0 0
M  V30 19 O -4.1452 -3.4717 0.0 0
M  V30 20 C -9.347 1.0566 0.0 0
M  V30 21 Si -10.6823 0.3599 0.0 0
M  V30 22 O -11.4835 1.6952 0.0 0
M  V30 23 O -9.9856 -0.9056 0.0 0
M  V30 24 O -12.0176 -0.3367 0.0 0
M  V30 25 C -11.1351 3.1814 0.0 0
M  V30 26 C -8.5226 -0.8708 0.0 0
M  V30 27 C -13.3529 0.4412 0.0 0
M  V30 28 C -9.6721 3.2163 0.0 0
M  V30 29 C -7.8143 -2.1364 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00038001.cdx

>  <name>
US20220000745A1-20220106-C00018

>  <Row No>
598

$$$$
US20220000745A1-20220106-C00019
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 31 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 0.7254 -1.2694 0.0 0
M  V30 3 O -0.7858 1.342 0.0 0
M  V30 4 O -1.342 -0.7254 0.0 0
M  V30 5 C 1.2694 0.7858 0.0 0
M  V30 6 C 2.2004 -1.2332 0.0 0
M  V30 7 C -0.4231 2.8412 0.0 0
M  V30 8 C -2.684 0.0483 0.0 0
M  V30 9 C 2.5389 0.0483 0.0 0
M  V30 10 C 3.8084 0.8342 0.0 0
M  V30 11 N 5.0779 0.0967 0.0 0
M  V30 12 C 6.3474 0.8825 0.0 0
M  V30 13 C 5.0416 -1.3783 0.0 0
M  V30 14 C 7.6169 0.145 0.0 0
M  V30 15 C 6.3111 -2.1037 0.0 0
M  V30 16 C 8.8864 0.9309 0.0 0
M  V30 17 C 6.2749 -3.5787 0.0 0
M  V30 18 Si 10.1559 0.1934 0.0 0
M  V30 19 Si 4.9328 -4.3162 0.0 0
M  V30 20 O 11.4254 -0.5319 0.0 0
M  V30 21 O 11.1836 1.2936 0.0 0
M  V30 22 O 9.0556 -0.8342 0.0 0
M  V30 23 O 3.5908 -3.5424 0.0 0
M  V30 24 O 3.5908 -5.0416 0.0 0
M  V30 25 O 6.2023 -5.0416 0.0 0
M  V30 26 C 12.9004 -0.4957 0.0 0
M  V30 27 C 10.0833 2.3938 0.0 0
M  V30 28 C 9.0194 -2.3092 0.0 0
M  V30 29 C 3.5545 -1.9949 0.0 0
M  V30 30 C 2.2488 -4.2679 0.0 0
M  V30 31 C 7.4718 -4.2679 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 19 24
M  V30 24 1 19 25
M  V30 25 1 20 26
M  V30 26 1 21 27
M  V30 27 1 22 28
M  V30 28 1 23 29
M  V30 29 1 24 30
M  V30 30 1 25 31
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00039001.cdx

>  <name>
US20220000745A1-20220106-C00019

>  <Row No>
599

$$$$
US20220000745A1-20220106-C00020
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 40 39 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2609 -0.7205 0.0 0
M  V30 3 O -1.0927 -1.0207 0.0 0
M  V30 4 O 1.0207 1.0927 0.0 0
M  V30 5 C -1.3329 0.7685 0.0 0
M  V30 6 C 2.6779 -0.2882 0.0 0
M  V30 7 C -1.1288 -2.4858 0.0 0
M  V30 8 C 0.2401 2.4257 0.0 0
M  V30 9 C -2.6659 0.048 0.0 0
M  V30 10 C 3.0382 1.2008 0.0 0
M  V30 11 C 0.3362 -2.4497 0.0 0
M  V30 12 C -1.2489 2.0655 0.0 0
M  V30 13 C -3.9989 0.8286 0.0 0
M  V30 14 N -5.3318 0.108 0.0 0
M  V30 15 C -5.3679 -1.3569 0.0 0
M  V30 16 C -6.6648 0.8766 0.0 0
M  V30 17 C -4.1069 -2.0775 0.0 0
M  V30 18 C -7.9978 0.1561 0.0 0
M  V30 19 C -4.143 -3.5425 0.0 0
M  V30 20 C -9.3308 0.9366 0.0 0
M  V30 21 Si -5.4759 -4.2751 0.0 0
M  V30 22 Si -10.6637 0.2161 0.0 0
M  V30 23 O -6.8089 -3.4945 0.0 0
M  V30 24 O -4.215 -5.0076 0.0 0
M  V30 25 O -6.8089 -5.0076 0.0 0
M  V30 26 O -11.9967 -0.5043 0.0 0
M  V30 27 O -11.4803 1.3089 0.0 0
M  V30 28 O -9.643 -0.8045 0.0 0
M  V30 29 C -6.8449 -1.9574 0.0 0
M  V30 30 C -2.798 -4.5753 0.0 0
M  V30 31 C -8.298 -4.5753 0.0 0
M  V30 32 C -13.3297 0.2641 0.0 0
M  V30 33 C -11.1201 2.798 0.0 0
M  V30 34 C -10.4236 -2.0655 0.0 0
M  V30 35 C -8.1779 -1.1888 0.0 0
M  V30 36 C -1.7772 -5.596 0.0 0
M  V30 37 C -9.3908 -5.596 0.0 0
M  V30 38 C -14.8188 -0.096 0.0 0
M  V30 39 C -9.655 2.834 0.0 0
M  V30 40 C -9.691 -3.3264 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 22 27
M  V30 27 1 22 28
M  V30 28 1 23 29
M  V30 29 1 24 30
M  V30 30 1 25 31
M  V30 31 1 26 32
M  V30 32 1 27 33
M  V30 33 1 28 34
M  V30 34 1 29 35
M  V30 35 1 30 36
M  V30 36 1 31 37
M  V30 37 1 32 38
M  V30 38 1 33 39
M  V30 39 1 34 40
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00040001.cdx

>  <name>
US20220000745A1-20220106-C00020

>  <Row No>
600

$$$$
US20220000745A1-20220106-C00021
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.1051 -1.0353 0.0 0
M  V30 3 O 1.0353 1.1051 0.0 0
M  V30 4 O 1.268 -0.698 0.0 0
M  V30 5 C -1.3378 0.791 0.0 0
M  V30 6 C -1.14 -2.5012 0.0 0
M  V30 7 C 0.2443 2.443 0.0 0
M  V30 8 C 2.7338 -0.6631 0.0 0
M  V30 9 C -2.6757 0.093 0.0 0
M  V30 10 C -4.0135 0.8841 0.0 0
M  V30 11 N -5.3514 0.1861 0.0 0
M  V30 12 C -5.3863 -1.2796 0.0 0
M  V30 13 C -6.6892 0.9772 0.0 0
M  V30 14 C -4.1182 -1.9777 0.0 0
M  V30 15 C -8.0271 0.2792 0.0 0
M  V30 16 N -4.1531 -3.4435 0.0 0
M  V30 17 C -9.3649 1.0702 0.0 0
M  V30 18 Si -10.7028 0.3722 0.0 0
M  V30 19 O -12.0407 -0.3257 0.0 0
M  V30 20 O -11.5404 1.4774 0.0 0
M  V30 21 O -9.6674 -0.6631 0.0 0
M  V30 22 C -13.3785 0.4537 0.0 0
M  V30 23 C -11.1914 2.9665 0.0 0
M  V30 24 C -8.2016 -0.6282 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00041001.cdx

>  <name>
US20220000745A1-20220106-C00021

>  <Row No>
601

$$$$
US20220000745A1-20220106-C00022
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -0.8485 1.1196 0.0 0
M  V30 3 O 1.0489 -1.0489 0.0 0
M  V30 4 O -1.3553 -0.7071 0.0 0
M  V30 5 C 1.2846 0.7896 0.0 0
M  V30 6 C -0.4949 2.6281 0.0 0
M  V30 7 C 2.5338 -1.0135 0.0 0
M  V30 8 C -2.7106 0.0824 0.0 0
M  V30 9 C 2.5692 0.0824 0.0 0
M  V30 10 C 0.9899 2.6635 0.0 0
M  V30 11 C 3.2527 -2.2981 0.0 0
M  V30 12 C -4.0659 -0.6246 0.0 0
M  V30 13 C 3.8538 0.8839 0.0 0
M  V30 14 N 5.1384 0.1767 0.0 0
M  V30 15 C 5.1031 -1.3081 0.0 0
M  V30 16 C 6.423 0.9781 0.0 0
M  V30 17 C 6.3877 -2.0271 0.0 0
M  V30 18 C 7.7077 0.271 0.0 0
M  V30 19 N 6.3523 -3.512 0.0 0
M  V30 20 C 8.9923 1.0724 0.0 0
M  V30 21 Si 10.2769 0.3653 0.0 0
M  V30 22 O 11.3258 1.4849 0.0 0
M  V30 23 O 11.5615 -0.3417 0.0 0
M  V30 24 O 9.1573 -0.6835 0.0 0
M  V30 25 C 10.5126 2.8403 0.0 0
M  V30 26 C 12.9993 0.0824 0.0 0
M  V30 27 C 9.1219 -2.1685 0.0 0
M  V30 28 C 11.5615 3.9599 0.0 0
M  V30 29 C 13.7065 1.4378 0.0 0
M  V30 30 C 10.4065 -2.8874 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00042001.cdx

>  <name>
US20220000745A1-20220106-C00022

>  <Row No>
602

$$$$
US20220000745A1-20220106-C00023
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.105 -1.0352 0.0 0
M  V30 3 O 1.0352 1.105 0.0 0
M  V30 4 O 1.2679 -0.6979 0.0 0
M  V30 5 C -1.3377 0.7793 0.0 0
M  V30 6 C -1.1399 -2.501 0.0 0
M  V30 7 C -0.0697 2.2101 0.0 0
M  V30 8 C 2.7336 -0.663 0.0 0
M  V30 9 C -2.6754 0.0814 0.0 0
M  V30 10 C -4.0132 0.8724 0.0 0
M  V30 11 N -5.3509 0.1744 0.0 0
M  V30 12 C -5.3858 -1.2912 0.0 0
M  V30 13 C -6.6887 0.9655 0.0 0
M  V30 14 C -4.1179 -1.9891 0.0 0
M  V30 15 C -8.0264 0.2675 0.0 0
M  V30 16 C -4.1528 -3.4548 0.0 0
M  V30 17 C -9.3642 1.0585 0.0 0
M  V30 18 Si -10.7019 0.3606 0.0 0
M  V30 19 O -12.0397 -0.3373 0.0 0
M  V30 20 O -11.5395 1.4657 0.0 0
M  V30 21 O -9.6666 -0.6746 0.0 0
M  V30 22 C -13.3774 0.442 0.0 0
M  V30 23 C -11.1905 2.9546 0.0 0
M  V30 24 C -8.2009 -0.6397 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 1 15 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00043001.cdx

>  <name>
US20220000745A1-20220106-C00023

>  <Row No>
603

$$$$
US20220000745A1-20220106-C00024
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.1069 -1.037 0.0 0
M  V30 3 O 1.27 -0.6991 0.0 0
M  V30 4 O 1.037 1.1069 0.0 0
M  V30 5 C -1.3399 0.7923 0.0 0
M  V30 6 C -1.1419 -2.5052 0.0 0
M  V30 7 C 2.7382 -0.6641 0.0 0
M  V30 8 C -0.0699 2.2139 0.0 0
M  V30 9 C -2.6799 0.0932 0.0 0
M  V30 10 C -0.1048 -3.5422 0.0 0
M  V30 11 C 3.7752 0.4427 0.0 0
M  V30 12 C 0.6292 3.5538 0.0 0
M  V30 13 C -4.0199 0.8855 0.0 0
M  V30 14 N -5.3599 0.1864 0.0 0
M  V30 15 C -5.3949 -1.2817 0.0 0
M  V30 16 C -6.6999 0.9787 0.0 0
M  V30 17 C -4.1248 -1.9925 0.0 0
M  V30 18 C -8.0399 0.2796 0.0 0
M  V30 19 C -4.1598 -3.4606 0.0 0
M  V30 20 C -9.3799 1.0719 0.0 0
M  V30 21 Si -10.7199 0.3728 0.0 0
M  V30 22 O -11.5588 1.4798 0.0 0
M  V30 23 O -12.0599 -0.3262 0.0 0
M  V30 24 O -9.6829 -0.6641 0.0 0
M  V30 25 C -11.2093 2.9712 0.0 0
M  V30 26 C -13.3999 0.466 0.0 0
M  V30 27 C -8.2147 -0.6292 0.0 0
M  V30 28 C -9.7411 3.0062 0.0 0
M  V30 29 C -14.7399 -0.233 0.0 0
M  V30 30 C -7.5156 -1.8992 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00044001.cdx

>  <name>
US20220000745A1-20220106-C00024

>  <Row No>
604

$$$$
US20220000745A1-20220106-C00025
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 7 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0322 1.0948 0.0 0
M  V30 3 O 1.272 -0.709 0.0 0
M  V30 4 O -1.0948 -1.0322 0.0 0
M  V30 5 C -1.3346 0.7715 0.0 0
M  V30 6 C -0.0625 2.1896 0.0 0
M  V30 7 C 2.5441 0.0625 0.0 0
M  V30 8 C -0.3857 -2.3043 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00045001.cdx

>  <name>
US20220000745A1-20220106-C00025

>  <Row No>
605

$$$$
US20220000745A1-20220106-C00026
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2686 -0.7216 0.0 0
M  V30 3 O 1.0358 1.1057 0.0 0
M  V30 4 O -1.1057 -1.0358 0.0 0
M  V30 5 C -1.3384 0.803 0.0 0
M  V30 6 C 2.5373 0.0814 0.0 0
M  V30 7 C -0.0698 2.2114 0.0 0
M  V30 8 C -0.4073 -2.3045 0.0 0
M  V30 9 C 3.8059 -0.6285 0.0 0
M  V30 10 C 0.966 3.3171 0.0 0
M  V30 11 C 1.0591 -2.2696 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00046001.cdx

>  <name>
US20220000745A1-20220106-C00026

>  <Row No>
606

$$$$
US20220000745A1-20220106-C00027
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0313 1.0938 0.0 0
M  V30 3 O 1.2708 -0.7083 0.0 0
M  V30 4 O -1.0938 -1.0313 0.0 0
M  V30 5 C -1.3334 0.7708 0.0 0
M  V30 6 C -0.0625 2.1876 0.0 0
M  V30 7 C 2.5417 0.0625 0.0 0
M  V30 8 C -0.3854 -2.3022 0.0 0
M  V30 9 C -2.6668 0.0625 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00047001.cdx

>  <name>
US20220000745A1-20220106-C00027

>  <Row No>
607

$$$$
US20220000745A1-20220106-C00028
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0367 1.1066 0.0 0
M  V30 3 O -1.1066 -1.0367 0.0 0
M  V30 4 O 1.2697 -0.6989 0.0 0
M  V30 5 C -1.3396 0.7921 0.0 0
M  V30 6 C -0.0698 2.2133 0.0 0
M  V30 7 C -0.4077 -2.3064 0.0 0
M  V30 8 C 2.5394 0.0931 0.0 0
M  V30 9 C -2.6792 0.0815 0.0 0
M  V30 10 C 0.9668 3.3199 0.0 0
M  V30 11 C 1.06 -2.2715 0.0 0
M  V30 12 C 3.8092 -0.6057 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00048001.cdx

>  <name>
US20220000745A1-20220106-C00028

>  <Row No>
608

$$$$
US20220000745A1-20220106-C00029
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0255 1.0877 0.0 0
M  V30 3 O 1.2638 -0.7044 0.0 0
M  V30 4 O -1.0877 -1.0255 0.0 0
M  V30 5 C -1.326 0.7666 0.0 0
M  V30 6 C -0.0621 2.1755 0.0 0
M  V30 7 C 2.5277 0.0621 0.0 0
M  V30 8 C -0.3833 -2.2894 0.0 0
M  V30 9 C -2.652 0.0621 0.0 0
M  V30 10 C -3.978 0.8287 0.0 0
M  V30 11 C -5.304 0.1243 0.0 0
M  V30 12 C -6.6301 0.8909 0.0 0
M  V30 13 C -7.9561 0.1864 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00049001.cdx

>  <name>
US20220000745A1-20220106-C00029

>  <Row No>
609

$$$$
US20220000745A1-20220106-C00030
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 15 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0246 1.0914 0.0 0
M  V30 3 O -1.0914 -1.0246 0.0 0
M  V30 4 O 1.2585 -0.7239 0.0 0
M  V30 5 C -1.3253 0.7907 0.0 0
M  V30 6 C -0.0668 2.1829 0.0 0
M  V30 7 C -0.3675 -2.2831 0.0 0
M  V30 8 C 2.517 0.0668 0.0 0
M  V30 9 C -2.6507 0.0668 0.0 0
M  V30 10 C 0.9578 3.2744 0.0 0
M  V30 11 C 1.0357 -1.8711 0.0 0
M  V30 12 C 3.7756 -0.6571 0.0 0
M  V30 13 C -3.976 0.8575 0.0 0
M  V30 14 C -5.3014 0.1336 0.0 0
M  V30 15 C -6.6268 0.9244 0.0 0
M  V30 16 C -7.9521 0.2004 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00050001.cdx

>  <name>
US20220000745A1-20220106-C00030

>  <Row No>
610

$$$$
US20220000745A1-20220106-C00031
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 14 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0239 1.086 0.0 0
M  V30 3 O 1.2618 -0.7033 0.0 0
M  V30 4 O -1.086 -1.0239 0.0 0
M  V30 5 C -1.3239 0.7653 0.0 0
M  V30 6 C -0.062 2.172 0.0 0
M  V30 7 C 2.5237 0.062 0.0 0
M  V30 8 C -0.3826 -2.2858 0.0 0
M  V30 9 C -2.6478 0.062 0.0 0
M  V30 10 C -3.9717 0.8274 0.0 0
M  V30 11 C -5.2957 0.1241 0.0 0
M  V30 12 C -6.6196 0.8895 0.0 0
M  V30 13 C -7.9435 0.1861 0.0 0
M  V30 14 C -9.2675 0.9515 0.0 0
M  V30 15 C -10.5914 0.2482 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00051001.cdx

>  <name>
US20220000745A1-20220106-C00031

>  <Row No>
611

$$$$
US20220000745A1-20220106-C00032
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 18 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0219 1.0886 0.0 0
M  V30 3 O -1.0886 -1.0219 0.0 0
M  V30 4 O 1.2552 -0.722 0.0 0
M  V30 5 C -1.3219 0.7887 0.0 0
M  V30 6 C -0.0666 2.1772 0.0 0
M  V30 7 C -0.3665 -2.2772 0.0 0
M  V30 8 C 2.5105 0.0666 0.0 0
M  V30 9 C -2.6438 0.0666 0.0 0
M  V30 10 C 0.6553 3.4991 0.0 0
M  V30 11 C 1.033 -1.8662 0.0 0
M  V30 12 C 3.7657 -0.6553 0.0 0
M  V30 13 C -3.9657 0.8553 0.0 0
M  V30 14 C -5.2876 0.1333 0.0 0
M  V30 15 C -6.6095 0.922 0.0 0
M  V30 16 C -7.9314 0.1999 0.0 0
M  V30 17 C -9.2533 0.9886 0.0 0
M  V30 18 C -10.5752 0.2666 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00052001.cdx

>  <name>
US20220000745A1-20220106-C00032

>  <Row No>
612

$$$$
US20220000745A1-20220106-C00033
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 19 18 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0218 1.0837 0.0 0
M  V30 3 O 1.2592 -0.7018 0.0 0
M  V30 4 O -1.0837 -1.0218 0.0 0
M  V30 5 C -1.3211 0.7637 0.0 0
M  V30 6 C -0.0619 2.1675 0.0 0
M  V30 7 C 2.5184 0.0619 0.0 0
M  V30 8 C -0.3818 -2.281 0.0 0
M  V30 9 C -2.6422 0.0619 0.0 0
M  V30 10 C -3.9634 0.8257 0.0 0
M  V30 11 C -5.2845 0.1238 0.0 0
M  V30 12 C -6.6057 0.8876 0.0 0
M  V30 13 C -7.9268 0.1857 0.0 0
M  V30 14 C -9.248 0.9495 0.0 0
M  V30 15 C -10.5691 0.2477 0.0 0
M  V30 16 C -11.8903 1.0115 0.0 0
M  V30 17 C -13.2114 0.3096 0.0 0
M  V30 18 C -14.5326 1.0734 0.0 0
M  V30 19 C -15.8537 0.3715 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00053001.cdx

>  <name>
US20220000745A1-20220106-C00033

>  <Row No>
613

$$$$
US20220000745A1-20220106-C00034
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2516 -0.7199 0.0 0
M  V30 3 O -1.0854 -1.019 0.0 0
M  V30 4 O 1.019 1.0854 0.0 0
M  V30 5 C -1.318 0.7864 0.0 0
M  V30 6 C 2.5032 0.0664 0.0 0
M  V30 7 C -0.3655 -2.2706 0.0 0
M  V30 8 C -0.0664 2.1709 0.0 0
M  V30 9 C -2.6361 0.0664 0.0 0
M  V30 10 C 3.7549 -0.6535 0.0 0
M  V30 11 C 1.0301 -1.8608 0.0 0
M  V30 12 C 0.6535 3.489 0.0 0
M  V30 13 C -3.9542 0.8528 0.0 0
M  V30 14 C -5.2723 0.1329 0.0 0
M  V30 15 C -6.5904 0.9193 0.0 0
M  V30 16 C -7.9085 0.1993 0.0 0
M  V30 17 C -9.2266 0.9858 0.0 0
M  V30 18 C -10.5447 0.2658 0.0 0
M  V30 19 C -11.8628 1.0522 0.0 0
M  V30 20 C -13.1809 0.3322 0.0 0
M  V30 21 C -14.499 1.1187 0.0 0
M  V30 22 C -15.8171 0.3987 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00054001.cdx

>  <name>
US20220000745A1-20220106-C00034

>  <Row No>
614

$$$$
US20220000746A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 13 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0206 1.0902 0.0 0
M  V30 3 O -1.0902 -1.0206 0.0 0
M  V30 4 O 1.2642 -0.719 0.0 0
M  V30 5 C -1.3338 0.777 0.0 0
M  V30 6 C -0.0695 2.1804 0.0 0
M  V30 7 C -0.3711 -2.2848 0.0 0
M  V30 8 C 2.5284 0.0579 0.0 0
M  V30 9 C -2.6676 0.0579 0.0 0
M  V30 10 C -1.5541 1.8209 0.0 0
M  V30 11 C 1.0438 -1.8557 0.0 0
M  V30 12 C 3.7926 -0.6611 0.0 0
M  V30 13 C -4.0014 0.835 0.0 0
M  V30 14 N -5.3352 0.1159 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000746A1-20220106-C00001

>  <Row No>
615

$$$$
US20220000746A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0278 1.0901 0.0 0
M  V30 3 O -1.0901 -1.0278 0.0 0
M  V30 4 O 1.2666 -0.706 0.0 0
M  V30 5 C -1.3289 0.7683 0.0 0
M  V30 6 C -0.0622 2.1803 0.0 0
M  V30 7 C -0.3841 -2.2945 0.0 0
M  V30 8 C 2.5333 0.0622 0.0 0
M  V30 9 C -2.6579 0.0622 0.0 0
M  V30 10 C -3.9868 0.8306 0.0 0
M  V30 11 N -5.3158 0.1245 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000746A1-20220106-C00002

>  <Row No>
616

$$$$
US20220000746A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 7 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2634 -0.7042 0.0 0
M  V30 3 O 1.0252 1.0874 0.0 0
M  V30 4 O -1.0874 -1.0252 0.0 0
M  V30 5 C -1.3255 0.7663 0.0 0
M  V30 6 C -2.6511 0.0621 0.0 0
M  V30 7 C -3.9767 0.8284 0.0 0
M  V30 8 N -5.3023 0.1242 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000746A1-20220106-C00003

>  <Row No>
617

$$$$
US20220000746A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0218 1.0915 0.0 0
M  V30 3 O -1.0915 -1.0218 0.0 0
M  V30 4 O 1.2656 -0.7199 0.0 0
M  V30 5 C -1.3353 0.7779 0.0 0
M  V30 6 C -0.0696 2.183 0.0 0
M  V30 7 C -0.3715 -2.2875 0.0 0
M  V30 8 C 2.5313 0.058 0.0 0
M  V30 9 C -2.6707 0.058 0.0 0
M  V30 10 C -1.5559 1.823 0.0 0
M  V30 11 C 1.045 -1.8578 0.0 0
M  V30 12 C 3.797 -0.6502 0.0 0
M  V30 13 N -4.006 0.836 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000746A1-20220106-C00004

>  <Row No>
618

$$$$
US20220000746A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 9 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0282 1.0905 0.0 0
M  V30 3 O -1.0905 -1.0282 0.0 0
M  V30 4 O 1.2671 -0.7062 0.0 0
M  V30 5 C -1.3294 0.7685 0.0 0
M  V30 6 C -0.0623 2.1811 0.0 0
M  V30 7 C -0.3842 -2.2953 0.0 0
M  V30 8 C 2.5342 0.0623 0.0 0
M  V30 9 C -2.6588 0.0623 0.0 0
M  V30 10 N -3.9883 0.8309 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000746A1-20220106-C00005

>  <Row No>
619

$$$$
US20220000746A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 7 6 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2636 -0.7043 0.0 0
M  V30 3 O 1.0253 1.0875 0.0 0
M  V30 4 O -1.0875 -1.0253 0.0 0
M  V30 5 C -1.3257 0.7664 0.0 0
M  V30 6 C -2.6515 0.0621 0.0 0
M  V30 7 N -3.9772 0.8285 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000746A1-20220106-C00006

>  <Row No>
620

$$$$
US20220000746A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 15 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0307 1.1001 0.0 0
M  V30 3 O -1.1001 -1.0307 0.0 0
M  V30 4 O 1.2623 -0.6948 0.0 0
M  V30 5 C -1.3318 0.7875 0.0 0
M  V30 6 C -0.0694 2.2003 0.0 0
M  V30 7 C -0.3705 -2.293 0.0 0
M  V30 8 C 2.5246 0.0926 0.0 0
M  V30 9 C -2.6636 0.0926 0.0 0
M  V30 10 C -1.5518 1.8529 0.0 0
M  V30 11 C 1.0422 -1.8761 0.0 0
M  V30 12 C 3.7869 -0.6022 0.0 0
M  V30 13 C -3.9954 0.8801 0.0 0
M  V30 14 N -5.3272 0.1852 0.0 0
M  V30 15 C -6.659 0.9727 0.0 0
M  V30 16 C -5.3619 -1.2739 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000746A1-20220106-C00007

>  <Row No>
621

$$$$
US20220000746A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.028 1.0973 0.0 0
M  V30 3 O -1.0973 -1.028 0.0 0
M  V30 4 O 1.259 -0.693 0.0 0
M  V30 5 C -1.3283 0.7854 0.0 0
M  V30 6 C -0.0693 2.1947 0.0 0
M  V30 7 C -0.4042 -2.2871 0.0 0
M  V30 8 C 2.5181 0.0924 0.0 0
M  V30 9 C -2.6567 0.0924 0.0 0
M  V30 10 C -3.9851 0.8778 0.0 0
M  V30 11 N -5.3135 0.1848 0.0 0
M  V30 12 C -6.6419 0.9703 0.0 0
M  V30 13 C -5.3482 -1.2706 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000746A1-20220106-C00008

>  <Row No>
622

$$$$
US20220000746A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 9 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2555 -0.6911 0.0 0
M  V30 3 O 1.0252 1.0943 0.0 0
M  V30 4 O -1.0943 -1.0252 0.0 0
M  V30 5 C -1.3246 0.7832 0.0 0
M  V30 6 C -2.6493 0.0806 0.0 0
M  V30 7 C -3.974 0.8639 0.0 0
M  V30 8 N -5.2987 0.1612 0.0 0
M  V30 9 C -6.6234 0.9445 0.0 0
M  V30 10 C -5.3333 -1.2901 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 8 10
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000746A1-20220106-C00009

>  <Row No>
623

$$$$
US20220000746A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 14 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2597 -0.7198 0.0 0
M  V30 3 O -1.0917 -1.0197 0.0 0
M  V30 4 O 1.0197 1.0917 0.0 0
M  V30 5 C -1.3317 0.7678 0.0 0
M  V30 6 C 2.5194 0.0479 0.0 0
M  V30 7 C -0.0719 -2.0395 0.0 0
M  V30 8 C -0.0719 2.1835 0.0 0
M  V30 9 C -2.6634 0.0479 0.0 0
M  V30 10 C 3.7791 -0.6718 0.0 0
M  V30 11 C 1.3437 -1.6076 0.0 0
M  V30 12 C -1.5596 1.8236 0.0 0
M  V30 13 N -3.9951 0.8158 0.0 0
M  V30 14 C -5.3268 0.0959 0.0 0
M  V30 15 C -4.0311 2.3514 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000746A1-20220106-C00010

>  <Row No>
624

$$$$
US20220000746A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2563 -0.7179 0.0 0
M  V30 3 O -1.0888 -1.017 0.0 0
M  V30 4 O 1.017 1.0888 0.0 0
M  V30 5 C -1.3281 0.7657 0.0 0
M  V30 6 C 2.5126 0.0478 0.0 0
M  V30 7 C -0.0717 -2.034 0.0 0
M  V30 8 C -0.0717 2.1776 0.0 0
M  V30 9 C -2.6562 0.0478 0.0 0
M  V30 10 N -3.9844 0.8255 0.0 0
M  V30 11 C -5.3125 0.1076 0.0 0
M  V30 12 C -4.0203 2.3571 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 10 12
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000746A1-20220106-C00011

>  <Row No>
625

$$$$
US20220000746A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2486 -0.7254 0.0 0
M  V30 3 O -1.0821 -1.0108 0.0 0
M  V30 4 O 1.0108 1.0821 0.0 0
M  V30 5 C -1.3199 0.7729 0.0 0
M  V30 6 C -2.6399 0.0475 0.0 0
M  V30 7 N -3.9599 0.8205 0.0 0
M  V30 8 C -5.2799 0.0951 0.0 0
M  V30 9 C -3.9956 2.3427 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000746A1-20220106-C00012

>  <Row No>
626

$$$$
US20220000746A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 20 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.3484 -0.7035 0.0 0
M  V30 3 O -0.7856 1.3484 0.0 0
M  V30 4 O 0.7035 -1.278 0.0 0
M  V30 5 C 1.278 0.7856 0.0 0
M  V30 6 C -2.6968 0.082 0.0 0
M  V30 7 C -0.4338 2.8493 0.0 0
M  V30 8 C 2.1809 -1.2429 0.0 0
M  V30 9 C 2.5561 0.082 0.0 0
M  V30 10 C 3.8342 0.8676 0.0 0
M  V30 11 N 5.1123 0.1641 0.0 0
M  V30 12 C 6.3904 0.9497 0.0 0
M  V30 13 C 7.6685 0.2462 0.0 0
M  V30 14 C 8.9466 1.0318 0.0 0
M  V30 15 Si 10.2247 0.3283 0.0 0
M  V30 16 O 9.1108 -0.7152 0.0 0
M  V30 17 O 11.5028 -0.3752 0.0 0
M  V30 18 O 11.2683 1.4422 0.0 0
M  V30 19 C 9.0756 -2.1926 0.0 0
M  V30 20 C 12.9802 -0.34 0.0 0
M  V30 21 C 10.1544 2.5561 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000746A1-20220106-C00013

>  <Row No>
627

$$$$
US20220000746A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -0.7966 1.3473 0.0 0
M  V30 3 O 0.7029 -1.277 0.0 0
M  V30 4 O -1.3473 -0.7029 0.0 0
M  V30 5 C 1.277 0.7966 0.0 0
M  V30 6 C -0.4452 2.847 0.0 0
M  V30 7 C 2.1791 -1.2419 0.0 0
M  V30 8 C -2.6947 0.0937 0.0 0
M  V30 9 C 2.5541 0.0937 0.0 0
M  V30 10 C 1.031 2.8821 0.0 0
M  V30 11 C 2.9055 -2.5189 0.0 0
M  V30 12 C -4.042 -0.6092 0.0 0
M  V30 13 C 3.8311 0.8904 0.0 0
M  V30 14 N 5.1082 0.1874 0.0 0
M  V30 15 C 6.3852 0.9841 0.0 0
M  V30 16 C 7.6623 0.2811 0.0 0
M  V30 17 C 8.9393 1.0778 0.0 0
M  V30 18 Si 10.2164 0.3749 0.0 0
M  V30 19 O 11.2591 1.4879 0.0 0
M  V30 20 O 11.4935 -0.328 0.0 0
M  V30 21 O 9.1034 -0.6678 0.0 0
M  V30 22 C 10.1461 2.6009 0.0 0
M  V30 23 C 12.9697 -0.2929 0.0 0
M  V30 24 C 9.0682 -2.144 0.0 0
M  V30 25 C 11.1888 3.714 0.0 0
M  V30 26 C 14.0124 0.8201 0.0 0
M  V30 27 C 10.4976 -2.4955 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000746A1-20220106-C00014

>  <Row No>
628

$$$$
US20220000746A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.3478 -0.7032 0.0 0
M  V30 3 O -0.7969 1.3478 0.0 0
M  V30 4 O 0.7032 -1.2775 0.0 0
M  V30 5 C 1.2775 0.7969 0.0 0
M  V30 6 C -2.6956 0.0937 0.0 0
M  V30 7 C -0.4453 2.848 0.0 0
M  V30 8 C 2.1799 -1.2423 0.0 0
M  V30 9 C 2.555 0.0937 0.0 0
M  V30 10 C 3.8325 0.8907 0.0 0
M  V30 11 N 5.11 0.1875 0.0 0
M  V30 12 C 6.3875 0.9845 0.0 0
M  V30 13 C 5.0748 -1.2892 0.0 0
M  V30 14 C 7.665 0.2812 0.0 0
M  V30 15 C 8.9425 1.0782 0.0 0
M  V30 16 Si 10.22 0.375 0.0 0
M  V30 17 O 9.1066 -0.668 0.0 0
M  V30 18 O 11.4975 -0.3281 0.0 0
M  V30 19 O 11.2631 1.4884 0.0 0
M  V30 20 C 9.0714 -2.1448 0.0 0
M  V30 21 C 12.9743 -0.293 0.0 0
M  V30 22 C 10.1497 2.6019 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00035001.cdx

>  <name>
US20220000746A1-20220106-C00015

>  <Row No>
629

$$$$
US20220000746A1-20220106-C00016
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -0.7862 1.3495 0.0 0
M  V30 3 O 0.7041 -1.2791 0.0 0
M  V30 4 O -1.3495 -0.7041 0.0 0
M  V30 5 C 1.2791 0.7862 0.0 0
M  V30 6 C -0.4341 2.8516 0.0 0
M  V30 7 C 2.1827 -1.2439 0.0 0
M  V30 8 C -2.699 0.0704 0.0 0
M  V30 9 C 2.5582 0.0821 0.0 0
M  V30 10 C 1.0444 2.8868 0.0 0
M  V30 11 C 2.8985 -2.523 0.0 0
M  V30 12 C -4.0485 -0.6336 0.0 0
M  V30 13 C 3.8373 0.8683 0.0 0
M  V30 14 N 5.1164 0.1642 0.0 0
M  V30 15 C 6.3956 0.9505 0.0 0
M  V30 16 C 5.0812 -1.3143 0.0 0
M  V30 17 C 7.6747 0.2464 0.0 0
M  V30 18 C 8.9538 1.0444 0.0 0
M  V30 19 Si 10.2329 0.3403 0.0 0
M  V30 20 O 9.1181 -0.7041 0.0 0
M  V30 21 O 11.2773 1.4551 0.0 0
M  V30 22 O 11.512 -0.3637 0.0 0
M  V30 23 C 9.0829 -2.1827 0.0 0
M  V30 24 C 10.1625 2.5699 0.0 0
M  V30 25 C 12.9906 -0.3285 0.0 0
M  V30 26 C 10.5146 -2.5347 0.0 0
M  V30 27 C 11.2069 3.6848 0.0 0
M  V30 28 C 14.0351 0.7862 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 19 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000746A1-20220106-C00016

>  <Row No>
630

$$$$
US20220000746A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.3498 -0.7042 0.0 0
M  V30 3 O -0.7981 1.3498 0.0 0
M  V30 4 O 0.7042 -1.2793 0.0 0
M  V30 5 C 1.2793 0.7981 0.0 0
M  V30 6 C -2.6996 0.0938 0.0 0
M  V30 7 C -0.446 2.8521 0.0 0
M  V30 8 C 2.1831 -1.2441 0.0 0
M  V30 9 C 2.5587 0.0938 0.0 0
M  V30 10 C 3.8381 0.892 0.0 0
M  V30 11 N 5.1175 0.1877 0.0 0
M  V30 12 C 5.0822 -1.2911 0.0 0
M  V30 13 C 6.3968 0.9859 0.0 0
M  V30 14 C 6.5142 -1.6432 0.0 0
M  V30 15 C 7.6762 0.2816 0.0 0
M  V30 16 O 6.479 -3.1221 0.0 0
M  V30 17 C 8.9556 1.0798 0.0 0
M  V30 18 Si 10.235 0.3755 0.0 0
M  V30 19 O 9.1199 -0.669 0.0 0
M  V30 20 O 11.5143 -0.3286 0.0 0
M  V30 21 O 11.2796 1.4906 0.0 0
M  V30 22 C 9.0847 -2.1479 0.0 0
M  V30 23 C 12.9933 -0.2934 0.0 0
M  V30 24 C 10.1645 2.6057 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000746A1-20220106-C00017

>  <Row No>
631

$$$$
US20220000746A1-20220106-C00018
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -0.7982 1.3499 0.0 0
M  V30 3 O 0.7043 -1.2795 0.0 0
M  V30 4 O -1.3499 -0.7043 0.0 0
M  V30 5 C 1.2795 0.7982 0.0 0
M  V30 6 C -0.446 2.8524 0.0 0
M  V30 7 C 2.1833 -1.2442 0.0 0
M  V30 8 C -2.6998 0.0939 0.0 0
M  V30 9 C 2.559 0.0939 0.0 0
M  V30 10 C 1.0329 2.8876 0.0 0
M  V30 11 C 2.8994 -2.5237 0.0 0
M  V30 12 C -4.0498 -0.6104 0.0 0
M  V30 13 C 3.8385 0.8921 0.0 0
M  V30 14 N 5.118 0.1878 0.0 0
M  V30 15 C 5.0828 -1.2912 0.0 0
M  V30 16 C 6.3975 0.986 0.0 0
M  V30 17 C 6.3623 -2.019 0.0 0
M  V30 18 C 7.677 0.2817 0.0 0
M  V30 19 O 6.327 -3.498 0.0 0
M  V30 20 C 8.9565 1.0799 0.0 0
M  V30 21 Si 10.236 0.3756 0.0 0
M  V30 22 O 9.1208 -0.669 0.0 0
M  V30 23 O 11.2807 1.4908 0.0 0
M  V30 24 O 11.5155 -0.3286 0.0 0
M  V30 25 C 9.0856 -2.1481 0.0 0
M  V30 26 C 10.1656 2.6059 0.0 0
M  V30 27 C 12.9946 -0.2934 0.0 0
M  V30 28 C 10.5177 -2.5003 0.0 0
M  V30 29 C 11.2103 3.7211 0.0 0
M  V30 30 C 14.0393 0.8217 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00038001.cdx

>  <name>
US20220000746A1-20220106-C00018

>  <Row No>
632

$$$$
US20220000746A1-20220106-C00019
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 31 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.342 -0.7254 0.0 0
M  V30 3 O -0.7738 1.342 0.0 0
M  V30 4 O 0.7254 -1.2695 0.0 0
M  V30 5 C 1.2695 0.7738 0.0 0
M  V30 6 C -2.6841 0.0483 0.0 0
M  V30 7 C -0.411 2.8413 0.0 0
M  V30 8 C 2.2005 -1.2332 0.0 0
M  V30 9 C 2.539 0.0362 0.0 0
M  V30 10 C 3.8086 0.81 0.0 0
M  V30 11 N 5.0781 0.0725 0.0 0
M  V30 12 C 6.3476 0.8584 0.0 0
M  V30 13 C 5.0418 -1.4025 0.0 0
M  V30 14 C 7.6172 0.1209 0.0 0
M  V30 15 C 6.3114 -2.1279 0.0 0
M  V30 16 C 8.8867 0.9068 0.0 0
M  V30 17 C 6.2751 -3.603 0.0 0
M  V30 18 Si 10.1563 0.1692 0.0 0
M  V30 19 Si 4.933 -4.3406 0.0 0
M  V30 20 O 9.056 -0.8584 0.0 0
M  V30 21 O 11.4258 -0.5561 0.0 0
M  V30 22 O 11.184 1.2695 0.0 0
M  V30 23 O 3.5909 -5.066 0.0 0
M  V30 24 O 6.2026 -5.066 0.0 0
M  V30 25 O 3.5909 -3.5547 0.0 0
M  V30 26 C 9.0197 -2.3335 0.0 0
M  V30 27 C 12.9009 -0.5199 0.0 0
M  V30 28 C 10.0837 2.3698 0.0 0
M  V30 29 C 2.2488 -4.2801 0.0 0
M  V30 30 C 7.6293 -4.6307 0.0 0
M  V30 31 C 3.5547 -2.007 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 19 24
M  V30 24 1 19 25
M  V30 25 1 20 26
M  V30 26 1 21 27
M  V30 27 1 22 28
M  V30 28 1 23 29
M  V30 29 1 24 30
M  V30 30 1 25 31
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00039001.cdx

>  <name>
US20220000746A1-20220106-C00019

>  <Row No>
633

$$$$
US20220000746A1-20220106-C00020
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 40 39 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.089 -1.0172 0.0 0
M  V30 3 O 1.0172 1.089 0.0 0
M  V30 4 O 1.2565 -0.73 0.0 0
M  V30 5 C -1.3283 0.7659 0.0 0
M  V30 6 C -1.1249 -2.4772 0.0 0
M  V30 7 C -0.0718 2.178 0.0 0
M  V30 8 C 2.7166 -0.6941 0.0 0
M  V30 9 C -2.6567 0.0359 0.0 0
M  V30 10 C 0.335 -2.4413 0.0 0
M  V30 11 C -1.5557 1.819 0.0 0
M  V30 12 C 3.0756 0.7898 0.0 0
M  V30 13 C -3.9851 0.8137 0.0 0
M  V30 14 N -5.3135 0.0837 0.0 0
M  V30 15 C -6.6419 0.8616 0.0 0
M  V30 16 C -5.3494 -1.3762 0.0 0
M  V30 17 C -7.9703 0.1316 0.0 0
M  V30 18 C -4.0928 -2.0943 0.0 0
M  V30 19 C -9.2987 0.9095 0.0 0
M  V30 20 C -4.1287 -3.5543 0.0 0
M  V30 21 Si -10.6271 0.1795 0.0 0
M  V30 22 Si -5.4571 -4.2843 0.0 0
M  V30 23 O -11.393 1.5079 0.0 0
M  V30 24 O -11.9555 -0.5385 0.0 0
M  V30 25 O -9.9091 -1.077 0.0 0
M  V30 26 O -6.7855 -3.5184 0.0 0
M  V30 27 O -6.7855 -5.0024 0.0 0
M  V30 28 O -4.2005 -5.0024 0.0 0
M  V30 29 C -11.034 2.9918 0.0 0
M  V30 30 C -13.2839 0.2273 0.0 0
M  V30 31 C -10.9981 -2.0943 0.0 0
M  V30 32 C -6.8214 -1.9866 0.0 0
M  V30 33 C -8.1139 -4.2245 0.0 0
M  V30 34 C -2.7884 -4.5715 0.0 0
M  V30 35 C -9.574 3.0277 0.0 0
M  V30 36 C -14.7679 -0.1316 0.0 0
M  V30 37 C -10.6391 -3.5064 0.0 0
M  V30 38 C -8.1498 -1.2087 0.0 0
M  V30 39 C -9.203 -5.2417 0.0 0
M  V30 40 C -1.7711 -5.5888 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 22 27
M  V30 27 1 22 28
M  V30 28 1 23 29
M  V30 29 1 24 30
M  V30 30 1 25 31
M  V30 31 1 26 32
M  V30 32 1 27 33
M  V30 33 1 28 34
M  V30 34 1 29 35
M  V30 35 1 30 36
M  V30 36 1 31 37
M  V30 37 1 32 38
M  V30 38 1 33 39
M  V30 39 1 34 40
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00040001.cdx

>  <name>
US20220000746A1-20220106-C00020

>  <Row No>
634

$$$$
US20220000746A1-20220106-C00021
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.3498 -0.7042 0.0 0
M  V30 3 O -0.7981 1.3498 0.0 0
M  V30 4 O 0.7042 -1.2793 0.0 0
M  V30 5 C 1.2793 0.7981 0.0 0
M  V30 6 C -2.6996 0.0938 0.0 0
M  V30 7 C -0.446 2.8521 0.0 0
M  V30 8 C 2.1831 -1.2441 0.0 0
M  V30 9 C 2.5587 0.0938 0.0 0
M  V30 10 C 3.8381 0.892 0.0 0
M  V30 11 N 5.1175 0.1877 0.0 0
M  V30 12 C 5.0822 -1.2911 0.0 0
M  V30 13 C 6.3968 0.9859 0.0 0
M  V30 14 C 6.5142 -1.6432 0.0 0
M  V30 15 C 7.6762 0.2816 0.0 0
M  V30 16 O 6.479 -3.1221 0.0 0
M  V30 17 C 8.9556 1.0798 0.0 0
M  V30 18 Si 10.235 0.3755 0.0 0
M  V30 19 O 9.1199 -0.669 0.0 0
M  V30 20 O 11.5143 -0.3286 0.0 0
M  V30 21 O 11.2796 1.4906 0.0 0
M  V30 22 C 9.0847 -2.1479 0.0 0
M  V30 23 C 12.9933 -0.2934 0.0 0
M  V30 24 C 10.1645 2.6057 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00041001.cdx

>  <name>
US20220000746A1-20220106-C00021

>  <Row No>
635

$$$$
US20220000746A1-20220106-C00022
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -0.7982 1.3499 0.0 0
M  V30 3 O 0.7043 -1.2795 0.0 0
M  V30 4 O -1.3499 -0.7043 0.0 0
M  V30 5 C 1.2795 0.7982 0.0 0
M  V30 6 C -0.446 2.8524 0.0 0
M  V30 7 C 2.1833 -1.2442 0.0 0
M  V30 8 C -2.6998 0.0939 0.0 0
M  V30 9 C 2.559 0.0939 0.0 0
M  V30 10 C 1.0329 2.8876 0.0 0
M  V30 11 C 2.8994 -2.5237 0.0 0
M  V30 12 C -4.0498 -0.6104 0.0 0
M  V30 13 C 3.8385 0.8921 0.0 0
M  V30 14 N 5.118 0.1878 0.0 0
M  V30 15 C 5.0828 -1.2912 0.0 0
M  V30 16 C 6.3975 0.986 0.0 0
M  V30 17 C 6.3623 -2.019 0.0 0
M  V30 18 C 7.677 0.2817 0.0 0
M  V30 19 N 6.327 -3.498 0.0 0
M  V30 20 C 8.9565 1.0799 0.0 0
M  V30 21 Si 10.236 0.3756 0.0 0
M  V30 22 O 9.1208 -0.669 0.0 0
M  V30 23 O 11.2807 1.4908 0.0 0
M  V30 24 O 11.5155 -0.3286 0.0 0
M  V30 25 C 9.0856 -2.1481 0.0 0
M  V30 26 C 10.1656 2.6059 0.0 0
M  V30 27 C 12.9946 -0.2934 0.0 0
M  V30 28 C 10.5177 -2.5003 0.0 0
M  V30 29 C 11.2103 3.7211 0.0 0
M  V30 30 C 14.0393 0.8217 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00042001.cdx

>  <name>
US20220000746A1-20220106-C00022

>  <Row No>
636

$$$$
US20220000746A1-20220106-C00023
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.3498 -0.7042 0.0 0
M  V30 3 O -0.7981 1.3498 0.0 0
M  V30 4 O 0.7042 -1.2793 0.0 0
M  V30 5 C 1.2793 0.7981 0.0 0
M  V30 6 C -2.6996 0.0938 0.0 0
M  V30 7 C -0.446 2.8521 0.0 0
M  V30 8 C 2.1831 -1.2441 0.0 0
M  V30 9 C 2.5587 0.0938 0.0 0
M  V30 10 C 3.8381 0.892 0.0 0
M  V30 11 N 5.1175 0.1877 0.0 0
M  V30 12 C 5.0822 -1.2911 0.0 0
M  V30 13 C 6.3968 0.9859 0.0 0
M  V30 14 C 6.5142 -1.6432 0.0 0
M  V30 15 C 7.6762 0.2816 0.0 0
M  V30 16 C 6.479 -3.1221 0.0 0
M  V30 17 C 8.9556 1.0798 0.0 0
M  V30 18 Si 10.235 0.3755 0.0 0
M  V30 19 O 9.1199 -0.669 0.0 0
M  V30 20 O 11.5143 -0.3286 0.0 0
M  V30 21 O 11.2796 1.4906 0.0 0
M  V30 22 C 9.0847 -2.1479 0.0 0
M  V30 23 C 12.9933 -0.2934 0.0 0
M  V30 24 C 10.1645 2.6057 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 1 15 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00043001.cdx

>  <name>
US20220000746A1-20220106-C00023

>  <Row No>
637

$$$$
US20220000746A1-20220106-C00024
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.3499 -0.7043 0.0 0
M  V30 3 O -0.7982 1.3499 0.0 0
M  V30 4 O 0.7043 -1.2795 0.0 0
M  V30 5 C 1.2795 0.7982 0.0 0
M  V30 6 C -2.6998 0.0939 0.0 0
M  V30 7 C -0.446 2.8524 0.0 0
M  V30 8 C 2.1833 -1.2442 0.0 0
M  V30 9 C 2.559 0.0939 0.0 0
M  V30 10 C -4.0498 -0.6104 0.0 0
M  V30 11 C 1.0329 2.8876 0.0 0
M  V30 12 C 2.8994 -2.5237 0.0 0
M  V30 13 C 3.8385 0.8921 0.0 0
M  V30 14 N 5.118 0.1878 0.0 0
M  V30 15 C 5.0828 -1.2912 0.0 0
M  V30 16 C 6.3975 0.986 0.0 0
M  V30 17 C 6.3623 -2.019 0.0 0
M  V30 18 C 7.677 0.2817 0.0 0
M  V30 19 C 6.327 -3.498 0.0 0
M  V30 20 C 8.9565 1.0799 0.0 0
M  V30 21 Si 10.236 0.3756 0.0 0
M  V30 22 O 9.1208 -0.669 0.0 0
M  V30 23 O 11.5155 -0.3286 0.0 0
M  V30 24 O 11.2807 1.4908 0.0 0
M  V30 25 C 9.0856 -2.1481 0.0 0
M  V30 26 C 12.9946 -0.2934 0.0 0
M  V30 27 C 10.1656 2.6059 0.0 0
M  V30 28 C 10.5177 -2.5003 0.0 0
M  V30 29 C 14.0393 0.8217 0.0 0
M  V30 30 C 11.2103 3.7211 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00044001.cdx

>  <name>
US20220000746A1-20220106-C00024

>  <Row No>
638

$$$$
US20220000746A1-20220106-C00025
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 7 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0322 1.0948 0.0 0
M  V30 3 O 1.272 -0.709 0.0 0
M  V30 4 O -1.0948 -1.0322 0.0 0
M  V30 5 C -1.3346 0.7715 0.0 0
M  V30 6 C -0.0625 2.1896 0.0 0
M  V30 7 C 2.5441 0.0625 0.0 0
M  V30 8 C -0.3857 -2.3043 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00045001.cdx

>  <name>
US20220000746A1-20220106-C00025

>  <Row No>
639

$$$$
US20220000746A1-20220106-C00026
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0358 1.1057 0.0 0
M  V30 3 O 1.2686 -0.7216 0.0 0
M  V30 4 O -1.1057 -1.0358 0.0 0
M  V30 5 C -1.3384 0.803 0.0 0
M  V30 6 C -0.0698 2.2114 0.0 0
M  V30 7 C 2.5373 0.0814 0.0 0
M  V30 8 C -0.4073 -2.3045 0.0 0
M  V30 9 C 0.966 3.3171 0.0 0
M  V30 10 C 3.8059 -0.6285 0.0 0
M  V30 11 C 1.0591 -2.2696 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00046001.cdx

>  <name>
US20220000746A1-20220106-C00026

>  <Row No>
640

$$$$
US20220000746A1-20220106-C00027
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0313 1.0938 0.0 0
M  V30 3 O 1.2708 -0.7083 0.0 0
M  V30 4 O -1.0938 -1.0313 0.0 0
M  V30 5 C -1.3334 0.7708 0.0 0
M  V30 6 C -0.0625 2.1876 0.0 0
M  V30 7 C 2.5417 0.0625 0.0 0
M  V30 8 C -0.3854 -2.3022 0.0 0
M  V30 9 C -2.6668 0.0625 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00047001.cdx

>  <name>
US20220000746A1-20220106-C00027

>  <Row No>
641

$$$$
US20220000746A1-20220106-C00028
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0367 1.1066 0.0 0
M  V30 3 O 1.2697 -0.6989 0.0 0
M  V30 4 O -1.1066 -1.0367 0.0 0
M  V30 5 C -1.3396 0.7921 0.0 0
M  V30 6 C -0.0698 2.2133 0.0 0
M  V30 7 C 2.5394 0.0931 0.0 0
M  V30 8 C -0.4077 -2.3064 0.0 0
M  V30 9 C -2.6792 0.0815 0.0 0
M  V30 10 C 0.9668 3.3199 0.0 0
M  V30 11 C 3.8092 -0.6057 0.0 0
M  V30 12 C 1.06 -2.2715 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00048001.cdx

>  <name>
US20220000746A1-20220106-C00028

>  <Row No>
642

$$$$
US20220000746A1-20220106-C00029
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0255 1.0877 0.0 0
M  V30 3 O -1.0877 -1.0255 0.0 0
M  V30 4 O 1.2638 -0.7044 0.0 0
M  V30 5 C -1.326 0.7666 0.0 0
M  V30 6 C -0.0621 2.1755 0.0 0
M  V30 7 C -0.3833 -2.2894 0.0 0
M  V30 8 C 2.5277 0.0621 0.0 0
M  V30 9 C -2.652 0.0621 0.0 0
M  V30 10 C -3.978 0.8287 0.0 0
M  V30 11 C -5.304 0.1243 0.0 0
M  V30 12 C -6.6301 0.8909 0.0 0
M  V30 13 C -7.9561 0.1864 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00049001.cdx

>  <name>
US20220000746A1-20220106-C00029

>  <Row No>
643

$$$$
US20220000746A1-20220106-C00030
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 15 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0246 1.0914 0.0 0
M  V30 3 O 1.2585 -0.7239 0.0 0
M  V30 4 O -1.0914 -1.0246 0.0 0
M  V30 5 C -1.3253 0.7907 0.0 0
M  V30 6 C -0.0668 2.1829 0.0 0
M  V30 7 C 2.517 0.0668 0.0 0
M  V30 8 C -0.3675 -2.2831 0.0 0
M  V30 9 C -2.6507 0.0668 0.0 0
M  V30 10 C 0.9578 3.2744 0.0 0
M  V30 11 C 3.7756 -0.6571 0.0 0
M  V30 12 C 1.0357 -1.8711 0.0 0
M  V30 13 C -3.976 0.8575 0.0 0
M  V30 14 C -5.3014 0.1336 0.0 0
M  V30 15 C -6.6268 0.9244 0.0 0
M  V30 16 C -7.9521 0.2004 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00050001.cdx

>  <name>
US20220000746A1-20220106-C00030

>  <Row No>
644

$$$$
US20220000746A1-20220106-C00031
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 14 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0239 1.086 0.0 0
M  V30 3 O 1.2618 -0.7033 0.0 0
M  V30 4 O -1.086 -1.0239 0.0 0
M  V30 5 C -1.3239 0.7653 0.0 0
M  V30 6 C -0.062 2.172 0.0 0
M  V30 7 C 2.5237 0.062 0.0 0
M  V30 8 C -0.3826 -2.2858 0.0 0
M  V30 9 C -2.6478 0.062 0.0 0
M  V30 10 C -3.9717 0.8274 0.0 0
M  V30 11 C -5.2957 0.1241 0.0 0
M  V30 12 C -6.6196 0.8895 0.0 0
M  V30 13 C -7.9435 0.1861 0.0 0
M  V30 14 C -9.2675 0.9515 0.0 0
M  V30 15 C -10.5914 0.2482 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00051001.cdx

>  <name>
US20220000746A1-20220106-C00031

>  <Row No>
645

$$$$
US20220000746A1-20220106-C00032
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 18 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0225 1.0891 0.0 0
M  V30 3 O 1.2559 -0.7224 0.0 0
M  V30 4 O -1.0891 -1.0225 0.0 0
M  V30 5 C -1.3225 0.7891 0.0 0
M  V30 6 C -0.0666 2.1783 0.0 0
M  V30 7 C 2.5118 0.0666 0.0 0
M  V30 8 C -0.3667 -2.2784 0.0 0
M  V30 9 C -2.6451 0.0666 0.0 0
M  V30 10 C 0.9558 3.2675 0.0 0
M  V30 11 C 3.7677 -0.6557 0.0 0
M  V30 12 C 1.0336 -1.8671 0.0 0
M  V30 13 C -3.9677 0.8557 0.0 0
M  V30 14 C -5.2903 0.1333 0.0 0
M  V30 15 C -6.6129 0.9224 0.0 0
M  V30 16 C -7.9355 0.2 0.0 0
M  V30 17 C -9.2581 0.9891 0.0 0
M  V30 18 C -10.5806 0.2667 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00052001.cdx

>  <name>
US20220000746A1-20220106-C00032

>  <Row No>
646

$$$$
US20220000746A1-20220106-C00033
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 19 18 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.0218 1.0837 0.0 0
M  V30 3 O 1.2592 -0.7018 0.0 0
M  V30 4 O -1.0837 -1.0218 0.0 0
M  V30 5 C -1.3211 0.7637 0.0 0
M  V30 6 C -0.0619 2.1675 0.0 0
M  V30 7 C 2.5184 0.0619 0.0 0
M  V30 8 C -0.3818 -2.281 0.0 0
M  V30 9 C -2.6422 0.0619 0.0 0
M  V30 10 C -3.9634 0.8257 0.0 0
M  V30 11 C -5.2845 0.1238 0.0 0
M  V30 12 C -6.6057 0.8876 0.0 0
M  V30 13 C -7.9268 0.1857 0.0 0
M  V30 14 C -9.248 0.9495 0.0 0
M  V30 15 C -10.5691 0.2477 0.0 0
M  V30 16 C -11.8903 1.0115 0.0 0
M  V30 17 C -13.2114 0.3096 0.0 0
M  V30 18 C -14.5326 1.0734 0.0 0
M  V30 19 C -15.8537 0.3715 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00053001.cdx

>  <name>
US20220000746A1-20220106-C00033

>  <Row No>
647

$$$$
US20220000746A1-20220106-C00034
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.019 1.0854 0.0 0
M  V30 3 O 1.2516 -0.7199 0.0 0
M  V30 4 O -1.0854 -1.019 0.0 0
M  V30 5 C -1.318 0.7864 0.0 0
M  V30 6 C -0.0664 2.1709 0.0 0
M  V30 7 C 2.5032 0.0664 0.0 0
M  V30 8 C -0.3655 -2.2706 0.0 0
M  V30 9 C -2.6361 0.0664 0.0 0
M  V30 10 C 0.6535 3.489 0.0 0
M  V30 11 C 3.7549 -0.6535 0.0 0
M  V30 12 C 1.0301 -1.8608 0.0 0
M  V30 13 C -3.9542 0.8528 0.0 0
M  V30 14 C -5.2723 0.1329 0.0 0
M  V30 15 C -6.5904 0.9193 0.0 0
M  V30 16 C -7.9085 0.1993 0.0 0
M  V30 17 C -9.2266 0.9858 0.0 0
M  V30 18 C -10.5447 0.2658 0.0 0
M  V30 19 C -11.8628 1.0522 0.0 0
M  V30 20 C -13.1809 0.3322 0.0 0
M  V30 21 C -14.499 1.1187 0.0 0
M  V30 22 C -15.8171 0.3987 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00054001.cdx

>  <name>
US20220000746A1-20220106-C00034

>  <Row No>
648

$$$$
US20220000746A1-20220106-C00035
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=15
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00055001.cdx

>  <name>
US20220000746A1-20220106-C00035

>  <Row No>
649

$$$$
US20220000746A1-20220106-C00036
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=16
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00057001.cdx

>  <name>
US20220000746A1-20220106-C00036

>  <Row No>
650

$$$$
US20220000746A1-20220106-C00038
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 13 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.0756 -1.0519 0.0 0
M  V30 3 N -2.5886 -1.0401 0.0 0
M  V30 4 ? -0.0472 -2.0803 0.0 0
M  V30 5 C -4.1016 -1.0283 0.0 0
M  V30 6 C -5.6145 -1.0165 0.0 0
M  V30 7 N -5.6264 -2.5058 0.0 0 CHG=1 CFG=2
M  V30 8 C -4.4207 -3.3805 0.0 0
M  V30 9 C -6.8793 -3.3569 0.0 0
M  V30 10 C -7.1157 -2.0803 0.0 0
M  V30 11 N -4.9172 -4.7753 0.0 0
M  V30 12 ? -2.9314 -3.3687 0.0 0
M  V30 13 C -6.4301 -4.7635 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 7 10 CFG=1
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 11 13
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 7)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00059001.cdx

>  <name>
US20220000746A1-20220106-C00038

>  <Row No>
651

$$$$
US20220000747A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 63 57 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.1313 -0.9771 0.0 0
M  V30 3 O 1.2085 -0.6685 0.0 0
M  V30 4 O 0.9771 1.1313 0.0 0
M  V30 5 C -1.3627 0.8228 0.0 0
M  V30 6 C -0.4628 -2.1856 0.0 0
M  V30 7 C 2.417 0.1542 0.0 0
M  V30 8 C -0.1542 2.2627 0.0 0
M  V30 9 C -2.7255 0.1542 0.0 0
M  V30 10 C 0.8999 -1.7227 0.0 0
M  V30 11 C 3.6255 -0.5142 0.0 0
M  V30 12 C -1.6713 1.9542 0.0 0
M  V30 13 N -4.0883 0.9771 0.0 0
M  V30 14 Si 0.6171 26.3303 0.0 0
M  V30 15 O -0.5142 25.3532 0.0 0
M  V30 16 O 1.8256 25.6617 0.0 0
M  V30 17 O 1.5942 27.4616 0.0 0
M  V30 18 C -0.7456 27.1531 0.0 0
M  V30 19 C 0.1542 24.1446 0.0 0
M  V30 20 C 3.0341 26.4845 0.0 0
M  V30 21 C 0.4628 28.593 0.0 0
M  V30 22 C -2.1084 26.4845 0.0 0
M  V30 23 C 1.517 24.6075 0.0 0
M  V30 24 C 4.2426 25.816 0.0 0
M  V30 25 C -1.0542 28.2845 0.0 0
M  V30 26 C -3.4712 27.3074 0.0 0
M  V30 27 N -4.834 26.6388 0.0 0
M  V30 28 Si 0.0 -6.7882 0.0 0
M  V30 29 O -1.1313 -7.7653 0.0 0
M  V30 30 O 1.2085 -7.4568 0.0 0
M  V30 31 O 0.9771 -5.6569 0.0 0
M  V30 32 C -1.3627 -5.9654 0.0 0
M  V30 33 C -0.4628 -8.9739 0.0 0
M  V30 34 C 2.417 -6.634 0.0 0
M  V30 35 C -0.1542 -4.5255 0.0 0
M  V30 36 C -2.7255 -6.634 0.0 0
M  V30 37 N -4.0883 -5.8111 0.0 0
M  V30 38 Si 0.8228 15.6336 0.0 0
M  V30 39 O -0.3085 14.6565 0.0 0
M  V30 40 O 2.0313 14.965 0.0 0
M  V30 41 O 1.7999 16.765 0.0 0
M  V30 42 C -0.5399 16.4564 0.0 0
M  V30 43 C 0.3599 13.448 0.0 0
M  V30 44 C 3.2398 15.7879 0.0 0
M  V30 45 C 0.6685 17.8963 0.0 0
M  V30 46 C -1.9027 15.7879 0.0 0
M  V30 47 C -3.2655 16.6107 0.0 0
M  V30 48 N -4.6283 15.9421 0.0 0
M  V30 49 Si -0.4114 -15.2222 0.0 0
M  V30 50 O 0.7971 -15.8907 0.0 0
M  V30 51 O 0.5656 -14.0908 0.0 0
M  V30 52 O -1.5427 -16.1993 0.0 0
M  V30 53 C -1.7742 -14.3993 0.0 0
M  V30 54 C -3.137 -15.0679 0.0 0
M  V30 55 N -4.4998 -14.2451 0.0 0
M  V30 56 Si 0.6171 8.4339 0.0 0
M  V30 57 O 1.8256 7.7653 0.0 0
M  V30 58 O 1.5942 9.5653 0.0 0
M  V30 59 O -0.5142 7.4568 0.0 0
M  V30 60 C -0.7456 9.2567 0.0 0
M  V30 61 C -2.1084 8.5882 0.0 0
M  V30 62 C -3.4712 9.411 0.0 0
M  V30 63 N -4.834 8.7424 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 14 15
M  V30 14 1 14 16
M  V30 15 1 14 17
M  V30 16 1 14 18
M  V30 17 1 15 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 26 27
M  V30 26 1 28 29
M  V30 27 1 28 30
M  V30 28 1 28 31
M  V30 29 1 28 32
M  V30 30 1 29 33
M  V30 31 1 30 34
M  V30 32 1 31 35
M  V30 33 1 32 36
M  V30 34 1 36 37
M  V30 35 1 38 39
M  V30 36 1 38 40
M  V30 37 1 38 41
M  V30 38 1 38 42
M  V30 39 1 39 43
M  V30 40 1 40 44
M  V30 41 1 41 45
M  V30 42 1 42 46
M  V30 43 1 46 47
M  V30 44 1 47 48
M  V30 45 1 49 50
M  V30 46 1 49 51
M  V30 47 1 49 52
M  V30 48 1 49 53
M  V30 49 1 53 54
M  V30 50 1 54 55
M  V30 51 1 56 57
M  V30 52 1 56 58
M  V30 53 1 56 59
M  V30 54 1 56 60
M  V30 55 1 60 61
M  V30 56 1 61 62
M  V30 57 1 62 63
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000747A1-20220106-C00001

>  <Row No>
652

$$$$
US20220000747A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 75 69 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.1178 -0.9654 0.0 0
M  V30 3 O 1.2194 -0.6605 0.0 0
M  V30 4 O 0.9654 1.1178 0.0 0
M  V30 5 C -1.3718 0.8129 0.0 0
M  V30 6 C -0.4572 -2.1848 0.0 0
M  V30 7 C 2.4389 0.1524 0.0 0
M  V30 8 C -0.1524 2.2356 0.0 0
M  V30 9 C -2.7437 0.1524 0.0 0
M  V30 10 C 0.8891 -1.7275 0.0 0
M  V30 11 C 3.6583 -0.5081 0.0 0
M  V30 12 C -1.6513 1.9308 0.0 0
M  V30 13 N -4.1156 0.9654 0.0 0
M  V30 14 C -5.4875 0.3048 0.0 0
M  V30 15 C -4.1918 2.5151 0.0 0
M  V30 16 Si 0.2032 26.015 0.0 0
M  V30 17 O -0.9145 25.0496 0.0 0
M  V30 18 O 1.4226 25.3544 0.0 0
M  V30 19 O 1.1686 27.1328 0.0 0
M  V30 20 C -1.1686 26.828 0.0 0
M  V30 21 C -0.254 23.8301 0.0 0
M  V30 22 C 2.6421 26.1674 0.0 0
M  V30 23 C 0.0508 28.2506 0.0 0
M  V30 24 C -2.5405 26.1674 0.0 0
M  V30 25 C 1.0924 24.2874 0.0 0
M  V30 26 C 3.8616 25.5069 0.0 0
M  V30 27 C -1.4481 27.9458 0.0 0
M  V30 28 C -3.9124 26.9804 0.0 0
M  V30 29 N -5.2843 26.3198 0.0 0
M  V30 30 C -6.6561 27.1328 0.0 0
M  V30 31 C -5.3605 24.9226 0.0 0
M  V30 32 Si 0.4064 -8.1296 0.0 0
M  V30 33 O -0.7113 -9.095 0.0 0
M  V30 34 O 1.6259 -8.7902 0.0 0
M  V30 35 O 1.3718 -7.0118 0.0 0
M  V30 36 C -0.9654 -7.3167 0.0 0
M  V30 37 C -0.0508 -10.3145 0.0 0
M  V30 38 C 2.8453 -7.9772 0.0 0
M  V30 39 C 0.254 -5.894 0.0 0
M  V30 40 C -2.3372 -7.9772 0.0 0
M  V30 41 N -3.7091 -7.1642 0.0 0
M  V30 42 C -5.081 -7.8248 0.0 0
M  V30 43 C -3.7853 -5.6145 0.0 0
M  V30 44 Si 1.0162 16.0561 0.0 0
M  V30 45 O -0.1016 15.0907 0.0 0
M  V30 46 O 2.2356 15.3956 0.0 0
M  V30 47 O 1.9816 17.1739 0.0 0
M  V30 48 C -0.3556 16.8691 0.0 0
M  V30 49 C 0.5589 13.8712 0.0 0
M  V30 50 C 3.4551 16.2085 0.0 0
M  V30 51 C 0.8637 18.2918 0.0 0
M  V30 52 C -1.7275 16.2085 0.0 0
M  V30 53 C -3.0994 17.0215 0.0 0
M  V30 54 N -4.4713 16.361 0.0 0
M  V30 55 C -5.8432 17.1739 0.0 0
M  V30 56 C -4.5475 14.9637 0.0 0
M  V30 57 Si -0.2032 -15.8529 0.0 0
M  V30 58 O 1.0162 -16.5134 0.0 0
M  V30 59 O 0.7621 -14.735 0.0 0
M  V30 60 O -1.321 -16.8183 0.0 0
M  V30 61 C -1.5751 -15.0399 0.0 0
M  V30 62 C -2.947 -15.7004 0.0 0
M  V30 63 N -4.3189 -14.8875 0.0 0
M  V30 64 C -5.6907 -15.548 0.0 0
M  V30 65 C -4.3951 -13.3377 0.0 0
M  V30 66 Si 0.8129 8.7394 0.0 0
M  V30 67 O 2.0324 8.0788 0.0 0
M  V30 68 O 1.7783 9.8572 0.0 0
M  V30 69 O -0.3048 7.774 0.0 0
M  V30 70 C -0.5589 9.5523 0.0 0
M  V30 71 C -1.9308 8.8918 0.0 0
M  V30 72 C -3.3026 9.7048 0.0 0
M  V30 73 N -4.6745 9.0442 0.0 0
M  V30 74 C -6.0464 9.8572 0.0 0
M  V30 75 C -4.7507 7.6469 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 15 1 16 17
M  V30 16 1 16 18
M  V30 17 1 16 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 28 29
M  V30 28 1 29 30
M  V30 29 1 29 31
M  V30 30 1 32 33
M  V30 31 1 32 34
M  V30 32 1 32 35
M  V30 33 1 32 36
M  V30 34 1 33 37
M  V30 35 1 34 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 1 40 41
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 44 45
M  V30 42 1 44 46
M  V30 43 1 44 47
M  V30 44 1 44 48
M  V30 45 1 45 49
M  V30 46 1 46 50
M  V30 47 1 47 51
M  V30 48 1 48 52
M  V30 49 1 52 53
M  V30 50 1 53 54
M  V30 51 1 54 55
M  V30 52 1 54 56
M  V30 53 1 57 58
M  V30 54 1 57 59
M  V30 55 1 57 60
M  V30 56 1 57 61
M  V30 57 1 61 62
M  V30 58 1 62 63
M  V30 59 1 63 64
M  V30 60 1 63 65
M  V30 61 1 66 67
M  V30 62 1 66 68
M  V30 63 1 66 69
M  V30 64 1 66 70
M  V30 65 1 70 71
M  V30 66 1 71 72
M  V30 67 1 72 73
M  V30 68 1 73 74
M  V30 69 1 73 75
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021002.cdx

>  <name>
US20220000747A1-20220106-C00002

>  <Row No>
653

$$$$
US20220000747A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 152 146 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.4598 -0.6122 0.0 0
M  V30 3 O 0.6122 -1.1773 0.0 0
M  V30 4 O -0.8947 1.4598 0.0 0
M  V30 5 C 1.1773 0.8947 0.0 0
M  V30 6 C -2.9197 0.2825 0.0 0
M  V30 7 C 1.9779 -1.036 0.0 0
M  V30 8 C -0.6593 3.061 0.0 0
M  V30 9 C 2.3546 0.2825 0.0 0
M  V30 10 C -4.3796 -0.3296 0.0 0
M  V30 11 C 2.5901 -2.2133 0.0 0
M  V30 12 C 0.7063 3.2023 0.0 0
M  V30 13 C 3.5319 1.1773 0.0 0
M  V30 14 N 4.7093 0.5651 0.0 0
M  V30 15 C 4.568 -0.8005 0.0 0
M  V30 16 C 5.8866 1.4598 0.0 0
M  V30 17 C 5.7453 -1.4127 0.0 0
M  V30 18 C 7.0639 0.8476 0.0 0
M  V30 19 O 5.604 -2.7784 0.0 0
M  V30 20 C 8.2413 1.7424 0.0 0
M  V30 21 Si 9.4186 1.1302 0.0 0
M  V30 22 O 10.3134 2.3546 0.0 0
M  V30 23 O 8.1942 0.1883 0.0 0
M  V30 24 O 10.5959 0.518 0.0 0
M  V30 25 C 9.136 3.5319 0.0 0
M  V30 26 C 8.0529 -1.1773 0.0 0
M  V30 27 C 11.9616 0.6593 0.0 0
M  V30 28 C 10.0308 4.7564 0.0 0
M  V30 29 C 9.3715 -1.4127 0.0 0
M  V30 30 C 12.9035 1.8837 0.0 0
M  V30 31 Si -1.1302 19.5907 0.0 0
M  V30 32 O -2.5901 18.9785 0.0 0
M  V30 33 O -0.518 18.4134 0.0 0
M  V30 34 O -2.025 21.0506 0.0 0
M  V30 35 C 0.047 20.4855 0.0 0
M  V30 36 C -4.05 19.8733 0.0 0
M  V30 37 C 0.8476 18.5547 0.0 0
M  V30 38 C -1.7895 22.6518 0.0 0
M  V30 39 C 1.2244 19.8733 0.0 0
M  V30 40 C -5.5099 19.2611 0.0 0
M  V30 41 C 1.4598 17.3773 0.0 0
M  V30 42 C -0.4238 22.7931 0.0 0
M  V30 43 C 2.4017 20.7681 0.0 0
M  V30 44 N 3.579 20.1558 0.0 0
M  V30 45 C 4.7564 21.0506 0.0 0
M  V30 46 C 3.4378 18.7901 0.0 0
M  V30 47 C 5.9337 20.4384 0.0 0
M  V30 48 C 7.111 21.3332 0.0 0
M  V30 49 Si 8.2884 20.721 0.0 0
M  V30 50 O 9.1831 21.9454 0.0 0
M  V30 51 O 7.0639 19.8262 0.0 0
M  V30 52 O 9.4657 20.1087 0.0 0
M  V30 53 C 8.0058 23.1698 0.0 0
M  V30 54 C 6.9227 18.4605 0.0 0
M  V30 55 C 10.8314 20.25 0.0 0
M  V30 56 C 8.9006 24.3471 0.0 0
M  V30 57 C 8.2413 18.225 0.0 0
M  V30 58 C 11.7733 21.4745 0.0 0
M  V30 59 Si -1.1302 37.6745 0.0 0
M  V30 60 O -2.5901 37.0623 0.0 0
M  V30 61 O -2.025 39.1344 0.0 0
M  V30 62 O -0.518 36.4972 0.0 0
M  V30 63 C 0.047 38.5693 0.0 0
M  V30 64 C -4.05 37.9571 0.0 0
M  V30 65 C -1.7895 40.7356 0.0 0
M  V30 66 C 0.8476 36.6385 0.0 0
M  V30 67 C 1.2244 37.9571 0.0 0
M  V30 68 C -5.5099 37.3449 0.0 0
M  V30 69 C -0.4238 40.8769 0.0 0
M  V30 70 C 1.4598 35.4611 0.0 0
M  V30 71 C 2.4017 38.8518 0.0 0
M  V30 72 N 3.579 38.2396 0.0 0
M  V30 73 C 4.7564 39.1344 0.0 0
M  V30 74 C 5.9337 38.5222 0.0 0
M  V30 75 C 7.111 39.417 0.0 0
M  V30 76 Si 8.2884 38.8048 0.0 0
M  V30 77 O 7.0639 37.8629 0.0 0
M  V30 78 O 9.4657 38.1925 0.0 0
M  V30 79 O 9.1831 39.9821 0.0 0
M  V30 80 C 6.9227 36.4972 0.0 0
M  V30 81 C 10.8314 38.3338 0.0 0
M  V30 82 C 8.0058 41.2065 0.0 0
M  V30 83 C 8.2413 36.2617 0.0 0
M  V30 84 C 11.7733 39.5111 0.0 0
M  V30 85 C 8.9006 42.4309 0.0 0
M  V30 86 Si 7.9116 10.9256 0.0 0
M  V30 87 O 6.6872 9.9837 0.0 0
M  V30 88 O 9.0889 10.3134 0.0 0
M  V30 89 O 8.8535 12.1029 0.0 0
M  V30 90 C 6.4517 11.8203 0.0 0
M  V30 91 C 6.5459 8.618 0.0 0
M  V30 92 C 10.4546 10.4546 0.0 0
M  V30 93 C 7.629 13.3273 0.0 0
M  V30 94 C 4.9918 11.2081 0.0 0
M  V30 95 C 3.5319 12.1029 0.0 0
M  V30 96 N 2.0721 11.4907 0.0 0
M  V30 97 C 1.9308 10.125 0.0 0
M  V30 98 C 0.6122 12.3855 0.0 0
M  V30 99 C 3.2494 9.8895 0.0 0
M  V30 100 C -0.8476 11.7733 0.0 0
M  V30 101 O 3.1081 8.5238 0.0 0
M  V30 102 C -2.3075 12.668 0.0 0
M  V30 103 Si -3.7674 12.0558 0.0 0
M  V30 104 O -5.2273 11.4436 0.0 0
M  V30 105 O -4.6622 13.5157 0.0 0
M  V30 106 O -3.1552 10.8785 0.0 0
M  V30 107 C -6.6872 12.3384 0.0 0
M  V30 108 C -4.4267 15.1169 0.0 0
M  V30 109 C -1.7895 11.0198 0.0 0
M  V30 110 Si 8.2884 28.6326 0.0 0
M  V30 111 O 7.0639 27.7378 0.0 0
M  V30 112 O 9.4657 28.0204 0.0 0
M  V30 113 O 9.2302 29.857 0.0 0
M  V30 114 C 6.8285 29.5274 0.0 0
M  V30 115 C 6.9227 26.3721 0.0 0
M  V30 116 C 10.8314 28.1617 0.0 0
M  V30 117 C 8.0058 31.0815 0.0 0
M  V30 118 C 5.3686 28.9152 0.0 0
M  V30 119 C 3.9087 29.8099 0.0 0
M  V30 120 N 2.4488 29.1977 0.0 0
M  V30 121 C 0.9889 30.0925 0.0 0
M  V30 122 C 2.3075 27.832 0.0 0
M  V30 123 C -0.4709 29.4803 0.0 0
M  V30 124 C -1.9308 30.3751 0.0 0
M  V30 125 Si -3.3907 29.7629 0.0 0
M  V30 126 O -4.8506 29.1506 0.0 0
M  V30 127 O -4.2854 31.2227 0.0 0
M  V30 128 O -2.7784 28.5855 0.0 0
M  V30 129 C -6.3104 30.0454 0.0 0
M  V30 130 C -4.05 32.8239 0.0 0
M  V30 131 C -1.4127 28.7268 0.0 0
M  V30 132 Si 8.6651 48.2234 0.0 0
M  V30 133 O 7.4878 47.3286 0.0 0
M  V30 134 O 9.8424 47.6112 0.0 0
M  V30 135 O 9.607 49.4478 0.0 0
M  V30 136 C 7.2052 49.1182 0.0 0
M  V30 137 C 7.3465 45.9629 0.0 0
M  V30 138 C 11.2081 47.7525 0.0 0
M  V30 139 C 8.3825 50.6722 0.0 0
M  V30 140 C 5.7453 48.506 0.0 0
M  V30 141 C 4.2854 49.4007 0.0 0
M  V30 142 N 2.8255 48.7885 0.0 0
M  V30 143 C 1.3657 49.6833 0.0 0
M  V30 144 C -0.0941 49.0711 0.0 0
M  V30 145 C -1.554 49.9658 0.0 0
M  V30 146 Si -3.0139 49.3536 0.0 0
M  V30 147 O -4.4738 48.7414 0.0 0
M  V30 148 O -3.9087 50.8135 0.0 0
M  V30 149 O -2.4017 48.1763 0.0 0
M  V30 150 C -5.9337 49.6362 0.0 0
M  V30 151 C -3.6732 52.4147 0.0 0
M  V30 152 C -1.036 48.3176 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 47 48
M  V30 47 1 48 49
M  V30 48 1 49 50
M  V30 49 1 49 51
M  V30 50 1 49 52
M  V30 51 1 50 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 59 60
M  V30 58 1 59 61
M  V30 59 1 59 62
M  V30 60 1 59 63
M  V30 61 1 60 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 71 72
M  V30 70 1 72 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 75 76
M  V30 74 1 76 77
M  V30 75 1 76 78
M  V30 76 1 76 79
M  V30 77 1 77 80
M  V30 78 1 78 81
M  V30 79 1 79 82
M  V30 80 1 80 83
M  V30 81 1 81 84
M  V30 82 1 82 85
M  V30 83 1 86 87
M  V30 84 1 86 88
M  V30 85 1 86 89
M  V30 86 1 86 90
M  V30 87 1 87 91
M  V30 88 1 88 92
M  V30 89 1 89 93
M  V30 90 1 90 94
M  V30 91 1 94 95
M  V30 92 1 95 96
M  V30 93 1 96 97
M  V30 94 1 96 98
M  V30 95 1 97 99
M  V30 96 1 98 100
M  V30 97 1 99 101
M  V30 98 1 100 102
M  V30 99 1 102 103
M  V30 100 1 103 104
M  V30 101 1 103 105
M  V30 102 1 103 106
M  V30 103 1 104 107
M  V30 104 1 105 108
M  V30 105 1 106 109
M  V30 106 1 110 111
M  V30 107 1 110 112
M  V30 108 1 110 113
M  V30 109 1 110 114
M  V30 110 1 111 115
M  V30 111 1 112 116
M  V30 112 1 113 117
M  V30 113 1 114 118
M  V30 114 1 118 119
M  V30 115 1 119 120
M  V30 116 1 120 121
M  V30 117 1 120 122
M  V30 118 1 121 123
M  V30 119 1 123 124
M  V30 120 1 124 125
M  V30 121 1 125 126
M  V30 122 1 125 127
M  V30 123 1 125 128
M  V30 124 1 126 129
M  V30 125 1 127 130
M  V30 126 1 128 131
M  V30 127 1 132 133
M  V30 128 1 132 134
M  V30 129 1 132 135
M  V30 130 1 132 136
M  V30 131 1 133 137
M  V30 132 1 134 138
M  V30 133 1 135 139
M  V30 134 1 136 140
M  V30 135 1 140 141
M  V30 136 1 141 142
M  V30 137 1 142 143
M  V30 138 1 143 144
M  V30 139 1 144 145
M  V30 140 1 145 146
M  V30 141 1 146 147
M  V30 142 1 146 148
M  V30 143 1 146 149
M  V30 144 1 147 150
M  V30 145 1 148 151
M  V30 146 1 149 152
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000747A1-20220106-C00003

>  <Row No>
654

$$$$
US20220000747A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 179 173 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.2274 -0.9072 0.0 0
M  V30 3 O 1.1206 -0.587 0.0 0
M  V30 4 O 0.9072 1.2274 0.0 0
M  V30 5 C -1.4408 0.9072 0.0 0
M  V30 6 C -1.3875 -2.2413 0.0 0
M  V30 7 C 2.4548 -0.4269 0.0 0
M  V30 8 C -0.3201 2.4548 0.0 0
M  V30 9 C -2.8817 0.3201 0.0 0
M  V30 10 C -0.1067 -2.4548 0.0 0
M  V30 11 C 3.362 0.8004 0.0 0
M  V30 12 C 0.587 3.6822 0.0 0
M  V30 13 C -4.3226 1.2274 0.0 0
M  V30 14 N -5.7635 0.6403 0.0 0
M  V30 15 C -5.9236 -0.6937 0.0 0
M  V30 16 C -7.2043 1.5476 0.0 0
M  V30 17 C -4.8029 -1.2807 0.0 0
M  V30 18 C -8.6452 0.9605 0.0 0
M  V30 19 C -4.963 -2.6149 0.0 0
M  V30 20 C -10.0861 1.8678 0.0 0
M  V30 21 Si -11.527 1.2807 0.0 0
M  V30 22 O -12.4342 2.7216 0.0 0
M  V30 23 O -10.9399 0.16 0.0 0
M  V30 24 O -12.9678 0.6937 0.0 0
M  V30 25 C -12.2207 4.3226 0.0 0
M  V30 26 C -9.6058 0.3201 0.0 0
M  V30 27 C -14.4087 1.6009 0.0 0
M  V30 28 C -10.8866 4.4827 0.0 0
M  V30 29 C -9.0188 -0.8004 0.0 0
M  V30 30 C -15.8496 1.0139 0.0 0
M  V30 31 Si -2.1346 20.4924 0.0 0
M  V30 32 O -3.362 19.5852 0.0 0
M  V30 33 O -1.0139 19.9054 0.0 0
M  V30 34 O -1.2274 21.7198 0.0 0
M  V30 35 C -3.5755 21.3996 0.0 0
M  V30 36 C -3.5221 18.251 0.0 0
M  V30 37 C 0.3201 20.0655 0.0 0
M  V30 38 C -2.4548 22.9472 0.0 0
M  V30 39 C -5.0163 20.8126 0.0 0
M  V30 40 C -2.2413 18.0376 0.0 0
M  V30 41 C 1.2274 21.2929 0.0 0
M  V30 42 C -1.5476 24.1746 0.0 0
M  V30 43 C -6.4572 21.7198 0.0 0
M  V30 44 N -7.8981 21.1328 0.0 0
M  V30 45 C -8.0582 19.7987 0.0 0
M  V30 46 C -9.339 22.04 0.0 0
M  V30 47 C -6.9375 19.2116 0.0 0
M  V30 48 C -10.7798 21.453 0.0 0
M  V30 49 N -7.0976 17.8775 0.0 0
M  V30 50 C -12.2207 22.3602 0.0 0
M  V30 51 Si -13.6616 21.7732 0.0 0
M  V30 52 O -14.5688 23.2141 0.0 0
M  V30 53 O -13.0746 20.6525 0.0 0
M  V30 54 O -15.1025 21.1862 0.0 0
M  V30 55 C -14.3553 24.815 0.0 0
M  V30 56 C -11.7404 20.8126 0.0 0
M  V30 57 C -16.5433 22.0934 0.0 0
M  V30 58 C -13.0212 24.9751 0.0 0
M  V30 59 C -11.1534 19.6919 0.0 0
M  V30 60 C -17.9842 21.5064 0.0 0
M  V30 61 Si -11.527 42.2656 0.0 0
M  V30 62 O -12.9678 41.6786 0.0 0
M  V30 63 O -12.4342 43.7065 0.0 0
M  V30 64 O -10.9399 41.145 0.0 0
M  V30 65 C -10.4063 43.1729 0.0 0
M  V30 66 C -14.4087 42.5858 0.0 0
M  V30 67 C -12.2207 45.3075 0.0 0
M  V30 68 C -12.1673 40.2377 0.0 0
M  V30 69 C -9.2856 42.5858 0.0 0
M  V30 70 C -15.8496 41.9988 0.0 0
M  V30 71 C -10.8866 45.4676 0.0 0
M  V30 72 C -11.9539 38.957 0.0 0
M  V30 73 C -8.1649 43.4931 0.0 0
M  V30 74 N -7.0442 42.906 0.0 0
M  V30 75 C -7.2043 41.5719 0.0 0
M  V30 76 C -5.9236 43.8132 0.0 0
M  V30 77 C -6.0836 40.9849 0.0 0
M  V30 78 C -4.8029 43.2262 0.0 0
M  V30 79 C -6.2437 39.6507 0.0 0
M  V30 80 C -3.6822 44.1334 0.0 0
M  V30 81 Si -7.6846 39.0637 0.0 0
M  V30 82 Si -2.5615 43.5464 0.0 0
M  V30 83 O -9.1255 39.9709 0.0 0
M  V30 84 O -9.1255 38.4767 0.0 0
M  V30 85 O -6.5639 38.4767 0.0 0
M  V30 86 O -3.7889 42.6392 0.0 0
M  V30 87 O -1.4408 42.9594 0.0 0
M  V30 88 O -1.6543 44.7738 0.0 0
M  V30 89 C -9.2856 41.6253 0.0 0
M  V30 90 C -10.5664 39.3839 0.0 0
M  V30 91 C -5.2832 39.0103 0.0 0
M  V30 92 C -3.949 41.3051 0.0 0
M  V30 93 C -0.1067 43.1195 0.0 0
M  V30 94 C -2.8817 46.0012 0.0 0
M  V30 95 C -10.7265 42.5325 0.0 0
M  V30 96 C -11.7938 38.4767 0.0 0
M  V30 97 C -4.3759 38.1031 0.0 0
M  V30 98 C -2.6149 41.4652 0.0 0
M  V30 99 C 0.1067 44.7205 0.0 0
M  V30 100 C -4.4827 45.7878 0.0 0
M  V30 101 Si -2.5615 11.1 0.0 0
M  V30 102 O -3.7889 10.1928 0.0 0
M  V30 103 O -1.4408 10.513 0.0 0
M  V30 104 O -1.6543 12.3274 0.0 0
M  V30 105 C -4.0024 12.0072 0.0 0
M  V30 106 C -3.949 8.8587 0.0 0
M  V30 107 C -0.1067 10.6731 0.0 0
M  V30 108 C -2.8817 13.5549 0.0 0
M  V30 109 C -5.4433 11.4202 0.0 0
M  V30 110 C -6.8841 12.3274 0.0 0
M  V30 111 N -8.325 11.7404 0.0 0
M  V30 112 C -8.4851 10.4063 0.0 0
M  V30 113 C -9.7659 12.6476 0.0 0
M  V30 114 C -7.2043 10.1928 0.0 0
M  V30 115 C -11.2068 12.0606 0.0 0
M  V30 116 C -7.3644 8.8587 0.0 0
M  V30 117 C -12.6476 12.9678 0.0 0
M  V30 118 Si -14.0885 12.3808 0.0 0
M  V30 119 O -15.5294 11.7938 0.0 0
M  V30 120 O -14.9957 13.8217 0.0 0
M  V30 121 O -13.5015 11.2601 0.0 0
M  V30 122 C -16.9703 12.701 0.0 0
M  V30 123 C -14.7823 15.4227 0.0 0
M  V30 124 C -12.1673 11.4202 0.0 0
M  V30 125 Si -2.5615 29.8848 0.0 0
M  V30 126 O -3.7889 28.9776 0.0 0
M  V30 127 O -1.4408 29.2978 0.0 0
M  V30 128 O -1.6543 31.1122 0.0 0
M  V30 129 C -4.0024 30.792 0.0 0
M  V30 130 C -3.949 27.6434 0.0 0
M  V30 131 C -0.1067 29.4579 0.0 0
M  V30 132 C -2.8817 32.3396 0.0 0
M  V30 133 C -5.4433 30.205 0.0 0
M  V30 134 C -6.8841 31.1122 0.0 0
M  V30 135 N -8.325 30.5252 0.0 0
M  V30 136 C -8.4851 29.191 0.0 0
M  V30 137 C -9.7659 31.4324 0.0 0
M  V30 138 C -7.2043 28.9776 0.0 0
M  V30 139 C -11.2068 30.8454 0.0 0
M  V30 140 N -7.3644 27.6434 0.0 0
M  V30 141 C -12.6476 31.7526 0.0 0
M  V30 142 Si -14.0885 31.1656 0.0 0
M  V30 143 O -15.5294 30.5785 0.0 0
M  V30 144 O -14.9957 32.6064 0.0 0
M  V30 145 O -13.5015 30.0449 0.0 0
M  V30 146 C -16.9703 31.4858 0.0 0
M  V30 147 C -14.7823 34.2074 0.0 0
M  V30 148 C -12.1673 30.205 0.0 0
M  V30 149 Si -2.5615 54.6465 0.0 0
M  V30 150 O -3.7889 53.7393 0.0 0
M  V30 151 O -1.4408 54.0595 0.0 0
M  V30 152 O -1.6543 55.8739 0.0 0
M  V30 153 C -4.0024 55.5537 0.0 0
M  V30 154 C -3.949 52.4051 0.0 0
M  V30 155 C -0.1067 54.2196 0.0 0
M  V30 156 C -2.8817 57.1013 0.0 0
M  V30 157 C -5.4433 54.9667 0.0 0
M  V30 158 C -6.8841 55.8739 0.0 0
M  V30 159 N -8.325 55.2869 0.0 0
M  V30 160 C -9.7659 56.1941 0.0 0
M  V30 161 C -8.4851 53.9527 0.0 0
M  V30 162 C -11.2068 55.6071 0.0 0
M  V30 163 C -7.3644 53.3657 0.0 0
M  V30 164 C -12.6476 56.5143 0.0 0
M  V30 165 C -7.5245 52.0316 0.0 0
M  V30 166 Si -14.0885 55.9273 0.0 0
M  V30 167 Si -8.9654 51.4446 0.0 0
M  V30 168 O -15.5294 55.3403 0.0 0
M  V30 169 O -14.9957 57.3682 0.0 0
M  V30 170 O -13.5015 54.8066 0.0 0
M  V30 171 O -10.4063 52.3518 0.0 0
M  V30 172 O -10.4063 50.8575 0.0 0
M  V30 173 O -7.8447 50.8575 0.0 0
M  V30 174 C -16.9703 56.2475 0.0 0
M  V30 175 C -14.7823 58.9691 0.0 0
M  V30 176 C -12.1673 54.9667 0.0 0
M  V30 177 C -10.5664 54.0061 0.0 0
M  V30 178 C -11.8472 51.7647 0.0 0
M  V30 179 C -6.5639 51.3912 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 46 48
M  V30 47 1 47 49
M  V30 48 1 48 50
M  V30 49 1 50 51
M  V30 50 1 51 52
M  V30 51 1 51 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 56 59
M  V30 58 1 57 60
M  V30 59 1 61 62
M  V30 60 1 61 63
M  V30 61 1 61 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 68 72
M  V30 70 1 69 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 74 76
M  V30 74 1 75 77
M  V30 75 1 76 78
M  V30 76 1 77 79
M  V30 77 1 78 80
M  V30 78 1 79 81
M  V30 79 1 80 82
M  V30 80 1 81 83
M  V30 81 1 81 84
M  V30 82 1 81 85
M  V30 83 1 82 86
M  V30 84 1 82 87
M  V30 85 1 82 88
M  V30 86 1 83 89
M  V30 87 1 84 90
M  V30 88 1 85 91
M  V30 89 1 86 92
M  V30 90 1 87 93
M  V30 91 1 88 94
M  V30 92 1 89 95
M  V30 93 1 90 96
M  V30 94 1 91 97
M  V30 95 1 92 98
M  V30 96 1 93 99
M  V30 97 1 94 100
M  V30 98 1 101 102
M  V30 99 1 101 103
M  V30 100 1 101 104
M  V30 101 1 101 105
M  V30 102 1 102 106
M  V30 103 1 103 107
M  V30 104 1 104 108
M  V30 105 1 105 109
M  V30 106 1 109 110
M  V30 107 1 110 111
M  V30 108 1 111 112
M  V30 109 1 111 113
M  V30 110 1 112 114
M  V30 111 1 113 115
M  V30 112 2 114 116
M  V30 113 1 115 117
M  V30 114 1 117 118
M  V30 115 1 118 119
M  V30 116 1 118 120
M  V30 117 1 118 121
M  V30 118 1 119 122
M  V30 119 1 120 123
M  V30 120 1 121 124
M  V30 121 1 125 126
M  V30 122 1 125 127
M  V30 123 1 125 128
M  V30 124 1 125 129
M  V30 125 1 126 130
M  V30 126 1 127 131
M  V30 127 1 128 132
M  V30 128 1 129 133
M  V30 129 1 133 134
M  V30 130 1 134 135
M  V30 131 1 135 136
M  V30 132 1 135 137
M  V30 133 1 136 138
M  V30 134 1 137 139
M  V30 135 1 138 140
M  V30 136 1 139 141
M  V30 137 1 141 142
M  V30 138 1 142 143
M  V30 139 1 142 144
M  V30 140 1 142 145
M  V30 141 1 143 146
M  V30 142 1 144 147
M  V30 143 1 145 148
M  V30 144 1 149 150
M  V30 145 1 149 151
M  V30 146 1 149 152
M  V30 147 1 149 153
M  V30 148 1 150 154
M  V30 149 1 151 155
M  V30 150 1 152 156
M  V30 151 1 153 157
M  V30 152 1 157 158
M  V30 153 1 158 159
M  V30 154 1 159 160
M  V30 155 1 159 161
M  V30 156 1 160 162
M  V30 157 1 161 163
M  V30 158 1 162 164
M  V30 159 1 163 165
M  V30 160 1 164 166
M  V30 161 1 165 167
M  V30 162 1 166 168
M  V30 163 1 166 169
M  V30 164 1 166 170
M  V30 165 1 167 171
M  V30 166 1 167 172
M  V30 167 1 167 173
M  V30 168 1 168 174
M  V30 169 1 169 175
M  V30 170 1 170 176
M  V30 171 1 171 177
M  V30 172 1 172 178
M  V30 173 1 173 179
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022002.cdx

>  <name>
US20220000747A1-20220106-C00004

>  <Row No>
655

$$$$
US20220000747A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 143 133 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.1882 -0.8487 0.0 0
M  V30 3 O 1.1316 -0.5658 0.0 0
M  V30 4 O 0.8487 1.1882 0.0 0
M  V30 5 C -1.4711 0.9053 0.0 0
M  V30 6 C -0.3394 -1.6974 0.0 0
M  V30 7 C 2.2632 0.3394 0.0 0
M  V30 8 C -0.3394 2.3764 0.0 0
M  V30 9 C -2.9422 0.3394 0.0 0
M  V30 10 C 0.9053 -1.1316 0.0 0
M  V30 11 C 3.3949 -0.2263 0.0 0
M  V30 12 C 0.2263 3.8475 0.0 0
M  V30 13 C -4.4133 1.2447 0.0 0
M  V30 14 C -5.8845 0.6789 0.0 0
M  V30 15 C -7.3556 1.5842 0.0 0
M  V30 16 C -8.8267 1.0184 0.0 0
M  V30 17 C -10.2978 1.9237 0.0 0
M  V30 18 C -11.769 1.3579 0.0 0
M  V30 19 C -13.2401 2.2632 0.0 0
M  V30 20 C -14.7112 1.6974 0.0 0
M  V30 21 C -16.1823 2.6027 0.0 0
M  V30 22 C -17.6535 2.0369 0.0 0
M  V30 23 Si -4.9791 17.2008 0.0 0
M  V30 24 O -4.1304 18.389 0.0 0
M  V30 25 O -3.8475 16.635 0.0 0
M  V30 26 O -6.1674 16.3521 0.0 0
M  V30 27 C -6.4503 18.1061 0.0 0
M  V30 28 C -5.3186 19.5772 0.0 0
M  V30 29 C -2.7159 17.5403 0.0 0
M  V30 30 C -5.3186 15.5034 0.0 0
M  V30 31 C -7.9214 17.5403 0.0 0
M  V30 32 C -4.4699 20.7655 0.0 0
M  V30 33 C -1.5842 16.9745 0.0 0
M  V30 34 C -4.0738 16.0692 0.0 0
M  V30 35 C -9.3925 18.4456 0.0 0
M  V30 36 C -10.8636 17.8798 0.0 0
M  V30 37 C -12.3348 18.7851 0.0 0
M  V30 38 C -13.8059 18.2193 0.0 0
M  V30 39 C -15.277 19.1246 0.0 0
M  V30 40 C -16.7482 18.5588 0.0 0
M  V30 41 Si -7.6951 31.6857 0.0 0
M  V30 42 O -6.8463 32.874 0.0 0
M  V30 43 O -6.5634 31.1199 0.0 0
M  V30 44 O -8.8833 30.837 0.0 0
M  V30 45 C -9.1662 32.591 0.0 0
M  V30 46 C -8.0346 34.0622 0.0 0
M  V30 47 C -5.4318 32.0252 0.0 0
M  V30 48 C -8.0346 29.9883 0.0 0
M  V30 49 C -10.6373 32.0252 0.0 0
M  V30 50 C -7.1858 35.2504 0.0 0
M  V30 51 C -4.3002 31.4594 0.0 0
M  V30 52 C -6.7898 30.5541 0.0 0
M  V30 53 C -12.1084 32.9305 0.0 0
M  V30 54 C -13.5796 32.3647 0.0 0
M  V30 55 C -15.0507 33.27 0.0 0
M  V30 56 C -16.5218 32.7042 0.0 0
M  V30 57 Si -2.2632 9.5057 0.0 0
M  V30 58 O -1.4711 10.6373 0.0 0
M  V30 59 O -3.3949 8.7135 0.0 0
M  V30 60 O -1.2447 8.9964 0.0 0
M  V30 61 C -3.6212 10.3544 0.0 0
M  V30 62 C -2.6027 11.769 0.0 0
M  V30 63 C -2.6027 7.9214 0.0 0
M  V30 64 C -0.2263 9.8452 0.0 0
M  V30 65 C -4.9791 9.8452 0.0 0
M  V30 66 C -6.3371 10.6939 0.0 0
M  V30 67 C -7.6951 10.1847 0.0 0
M  V30 68 C -9.053 11.0334 0.0 0
M  V30 69 C -10.411 10.5242 0.0 0
M  V30 70 C -11.769 11.3729 0.0 0
M  V30 71 C -13.1269 10.8636 0.0 0
M  V30 72 C -14.4849 11.7124 0.0 0
M  V30 73 C -15.8428 11.2031 0.0 0
M  V30 74 C -17.2008 12.0519 0.0 0
M  V30 75 C -18.5588 11.5426 0.0 0
M  V30 76 Si -4.9791 24.4433 0.0 0
M  V30 77 O -4.1304 25.6315 0.0 0
M  V30 78 O -6.1674 23.5945 0.0 0
M  V30 79 O -3.8475 23.8775 0.0 0
M  V30 80 C -6.4503 25.3486 0.0 0
M  V30 81 C -5.3186 26.8197 0.0 0
M  V30 82 C -5.3186 22.7458 0.0 0
M  V30 83 C -2.7159 24.7828 0.0 0
M  V30 84 C -7.9214 24.7828 0.0 0
M  V30 85 C -9.3925 25.6881 0.0 0
M  V30 86 C -10.8636 25.1223 0.0 0
M  V30 87 C -12.3348 26.0276 0.0 0
M  V30 88 C -13.8059 25.4617 0.0 0
M  V30 89 C -15.277 26.3671 0.0 0
M  V30 90 C -16.7482 25.8012 0.0 0
M  V30 91 Si -7.6951 40.2862 0.0 0
M  V30 92 O -6.8463 41.4744 0.0 0
M  V30 93 O -8.8833 39.4374 0.0 0
M  V30 94 O -6.5634 39.7203 0.0 0
M  V30 95 C -9.1662 41.1915 0.0 0
M  V30 96 C -8.0346 42.6626 0.0 0
M  V30 97 C -8.0346 38.5887 0.0 0
M  V30 98 C -5.4318 40.6257 0.0 0
M  V30 99 C -10.6373 40.6257 0.0 0
M  V30 100 C -12.1084 41.531 0.0 0
M  V30 101 C -13.5796 40.9651 0.0 0
M  V30 102 C -15.0507 41.8705 0.0 0
M  V30 103 C -16.5218 41.3046 0.0 0
M  V30 104 Si -5.8845 48.8866 0.0 0
M  V30 105 O -7.0727 48.0379 0.0 0
M  V30 106 O -4.7528 48.3208 0.0 0
M  V30 107 O -5.0357 50.0748 0.0 0
M  V30 108 C -7.3556 49.7919 0.0 0
M  V30 109 C -6.2239 47.1891 0.0 0
M  V30 110 C -3.6212 49.2261 0.0 0
M  V30 111 C -6.2239 51.263 0.0 0
M  V30 112 C -8.8267 49.2261 0.0 0
M  V30 113 C -4.9226 47.3589 0.0 0
M  V30 114 C -2.4895 48.6603 0.0 0
M  V30 115 C -5.3752 52.4512 0.0 0
M  V30 116 Si -12.2216 49.3392 0.0 0
M  V30 117 O -11.3729 50.5275 0.0 0
M  V30 118 O -13.4098 48.4905 0.0 0
M  V30 119 O -11.09 48.7734 0.0 0
M  V30 120 C -13.6927 50.2446 0.0 0
M  V30 121 C -12.5611 51.7157 0.0 0
M  V30 122 C -12.5611 47.6418 0.0 0
M  V30 123 C -9.9583 49.6787 0.0 0
M  V30 124 C -15.1639 49.6787 0.0 0
M  V30 125 Si -6.3371 57.487 0.0 0
M  V30 126 O -7.5253 56.6383 0.0 0
M  V30 127 O -5.2055 56.9212 0.0 0
M  V30 128 O -5.4884 58.6752 0.0 0
M  V30 129 C -7.8082 58.3923 0.0 0
M  V30 130 C -6.6766 55.7896 0.0 0
M  V30 131 C -4.0738 57.8265 0.0 0
M  V30 132 C -6.6766 59.8635 0.0 0
M  V30 133 C -5.3752 55.9593 0.0 0
M  V30 134 C -2.9422 57.2607 0.0 0
M  V30 135 C -5.8279 61.0517 0.0 0
M  V30 136 Si -12.6743 57.9397 0.0 0
M  V30 137 O -11.8255 59.1279 0.0 0
M  V30 138 O -13.8625 57.0909 0.0 0
M  V30 139 O -11.5426 57.3739 0.0 0
M  V30 140 C -14.1454 58.845 0.0 0
M  V30 141 C -13.0138 60.3161 0.0 0
M  V30 142 C -13.0138 56.2422 0.0 0
M  V30 143 C -10.411 58.2792 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 23 24
M  V30 23 1 23 25
M  V30 24 1 23 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 25 29
M  V30 28 1 26 30
M  V30 29 1 27 31
M  V30 30 1 28 32
M  V30 31 1 29 33
M  V30 32 1 30 34
M  V30 33 1 31 35
M  V30 34 1 35 36
M  V30 35 1 36 37
M  V30 36 1 37 38
M  V30 37 1 38 39
M  V30 38 1 39 40
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 41 44
M  V30 42 1 41 45
M  V30 43 1 42 46
M  V30 44 1 43 47
M  V30 45 1 44 48
M  V30 46 1 45 49
M  V30 47 1 46 50
M  V30 48 1 47 51
M  V30 49 1 48 52
M  V30 50 1 49 53
M  V30 51 1 53 54
M  V30 52 1 54 55
M  V30 53 1 55 56
M  V30 54 1 57 58
M  V30 55 1 57 59
M  V30 56 1 57 60
M  V30 57 1 57 61
M  V30 58 1 58 62
M  V30 59 1 59 63
M  V30 60 1 60 64
M  V30 61 1 61 65
M  V30 62 1 65 66
M  V30 63 1 66 67
M  V30 64 1 67 68
M  V30 65 1 68 69
M  V30 66 1 69 70
M  V30 67 1 70 71
M  V30 68 1 71 72
M  V30 69 1 72 73
M  V30 70 1 73 74
M  V30 71 1 74 75
M  V30 72 1 76 77
M  V30 73 1 76 78
M  V30 74 1 76 79
M  V30 75 1 76 80
M  V30 76 1 77 81
M  V30 77 1 78 82
M  V30 78 1 79 83
M  V30 79 1 80 84
M  V30 80 1 84 85
M  V30 81 1 85 86
M  V30 82 1 86 87
M  V30 83 1 87 88
M  V30 84 1 88 89
M  V30 85 1 89 90
M  V30 86 1 91 92
M  V30 87 1 91 93
M  V30 88 1 91 94
M  V30 89 1 91 95
M  V30 90 1 92 96
M  V30 91 1 93 97
M  V30 92 1 94 98
M  V30 93 1 95 99
M  V30 94 1 99 100
M  V30 95 1 100 101
M  V30 96 1 101 102
M  V30 97 1 102 103
M  V30 98 1 104 105
M  V30 99 1 104 106
M  V30 100 1 104 107
M  V30 101 1 104 108
M  V30 102 1 105 109
M  V30 103 1 106 110
M  V30 104 1 107 111
M  V30 105 1 108 112
M  V30 106 1 109 113
M  V30 107 1 110 114
M  V30 108 1 111 115
M  V30 109 1 116 117
M  V30 110 1 116 118
M  V30 111 1 116 119
M  V30 112 1 116 120
M  V30 113 1 117 121
M  V30 114 1 118 122
M  V30 115 1 119 123
M  V30 116 1 120 124
M  V30 117 1 125 126
M  V30 118 1 125 127
M  V30 119 1 125 128
M  V30 120 1 125 129
M  V30 121 1 126 130
M  V30 122 1 127 131
M  V30 123 1 128 132
M  V30 124 1 130 133
M  V30 125 1 131 134
M  V30 126 1 132 135
M  V30 127 1 136 137
M  V30 128 1 136 138
M  V30 129 1 136 139
M  V30 130 1 136 140
M  V30 131 1 137 141
M  V30 132 1 138 142
M  V30 133 1 139 143
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000747A1-20220106-C00005

>  <Row No>
656

$$$$
US20220000747A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 13 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.7693 -1.29 0.0 0
M  V30 3 N -2.2842 -1.2782 0.0 0
M  V30 4 ? -0.0473 -2.5565 0.0 0
M  V30 5 C -3.7992 -1.2664 0.0 0
M  V30 6 C -5.3142 -1.2545 0.0 0
M  V30 7 N -5.3378 -2.7458 0.0 0 CHG=1 CFG=2
M  V30 8 C -4.1306 -3.6217 0.0 0
M  V30 9 C -6.5924 -3.598 0.0 0
M  V30 10 C -6.8055 -2.3197 0.0 0
M  V30 11 N -4.6277 -5.0183 0.0 0
M  V30 12 ? -2.6393 -3.6098 0.0 0
M  V30 13 C -6.1427 -5.0064 0.0 0
M  V30 14 C 1.5149 -2.3671 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 7 10 CFG=1
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 11 13
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 7)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000747A1-20220106-C00006

>  <Row No>
657

$$$$
US20220000747A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=15
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000747A1-20220106-C00007

>  <Row No>
658

$$$$
US20220000747A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=16
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000747A1-20220106-C00008

>  <Row No>
659

$$$$
US20220000748A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 102 93 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.1813 -0.6412 0.0 0
M  V30 3 O -1.1475 -0.945 0.0 0
M  V30 4 O 0.945 1.1475 0.0 0
M  V30 5 C -1.3838 0.8438 0.0 0
M  V30 6 C 2.3626 0.2025 0.0 0
M  V30 7 C -0.5062 -2.1264 0.0 0
M  V30 8 C -0.2025 2.2951 0.0 0
M  V30 9 C -2.7677 0.2025 0.0 0
M  V30 10 C 3.544 -0.4387 0.0 0
M  V30 11 C 0.8438 -1.6538 0.0 0
M  V30 12 C -1.7551 2.0251 0.0 0
M  V30 13 N -4.1515 1.0463 0.0 0
M  V30 14 Si 1.08 -19.9814 0.0 0
M  V30 15 O 2.2614 -20.6227 0.0 0
M  V30 16 O -0.0675 -20.9265 0.0 0
M  V30 17 O 2.0251 -18.8338 0.0 0
M  V30 18 C -0.3037 -19.1376 0.0 0
M  V30 19 C 3.4427 -19.7789 0.0 0
M  V30 20 C 0.5737 -22.1078 0.0 0
M  V30 21 C 0.8775 -17.6862 0.0 0
M  V30 22 C -1.6876 -19.7789 0.0 0
M  V30 23 C 4.624 -20.4202 0.0 0
M  V30 24 C 1.9238 -21.6353 0.0 0
M  V30 25 C -0.675 -17.9563 0.0 0
M  V30 26 C -3.0714 -18.9351 0.0 0
M  V30 27 N -4.4553 -19.5764 0.0 0
M  V30 28 C -5.8391 -18.7326 0.0 0
M  V30 29 C -4.5565 -20.9602 0.0 0
M  V30 30 Si 0.54 22.9516 0.0 0
M  V30 31 O 1.7213 22.3103 0.0 0
M  V30 32 O -0.6075 22.0065 0.0 0
M  V30 33 O 1.4851 24.0992 0.0 0
M  V30 34 C -0.8438 23.7954 0.0 0
M  V30 35 C 2.9027 23.1541 0.0 0
M  V30 36 C 0.0337 20.8252 0.0 0
M  V30 37 C 0.3375 25.2468 0.0 0
M  V30 38 C -2.2276 23.1541 0.0 0
M  V30 39 C 4.084 22.5128 0.0 0
M  V30 40 C 1.3838 21.2977 0.0 0
M  V30 41 C -1.215 24.9768 0.0 0
M  V30 42 C -3.6115 23.9979 0.0 0
M  V30 43 N -4.9953 23.3566 0.0 0
M  V30 44 Si -0.27 -6.4804 0.0 0
M  V30 45 O 0.9113 -7.1217 0.0 0
M  V30 46 O -1.4176 -7.4255 0.0 0
M  V30 47 O 0.675 -5.3328 0.0 0
M  V30 48 C -1.6538 -5.6366 0.0 0
M  V30 49 C 2.0926 -6.2779 0.0 0
M  V30 50 C -0.7763 -8.6068 0.0 0
M  V30 51 C -0.4725 -4.1853 0.0 0
M  V30 52 C -3.0377 -6.2779 0.0 0
M  V30 53 N -4.4215 -5.4341 0.0 0
M  V30 54 Si 1.8901 -27.542 0.0 0
M  V30 55 O 3.0714 -28.1832 0.0 0
M  V30 56 O 0.7425 -28.487 0.0 0
M  V30 57 O 2.8352 -26.3944 0.0 0
M  V30 58 C 0.5062 -26.6981 0.0 0
M  V30 59 C 4.2528 -27.3394 0.0 0
M  V30 60 C 1.3838 -29.6684 0.0 0
M  V30 61 C 1.6876 -25.2468 0.0 0
M  V30 62 C -0.8775 -27.3394 0.0 0
M  V30 63 C -2.2614 -26.4956 0.0 0
M  V30 64 N -3.6452 -27.1369 0.0 0
M  V30 65 C -5.0291 -26.2931 0.0 0
M  V30 66 C -3.7465 -28.5208 0.0 0
M  V30 67 Si 0.54 14.851 0.0 0
M  V30 68 O 1.7213 14.2097 0.0 0
M  V30 69 O -0.6075 13.906 0.0 0
M  V30 70 O 1.4851 15.9986 0.0 0
M  V30 71 C -0.8438 15.6948 0.0 0
M  V30 72 C 2.9027 15.0535 0.0 0
M  V30 73 C 0.0337 12.7246 0.0 0
M  V30 74 C 0.3375 17.1462 0.0 0
M  V30 75 C -2.2276 15.0535 0.0 0
M  V30 76 C -3.6115 15.8974 0.0 0
M  V30 77 N -4.9953 15.2561 0.0 0
M  V30 78 Si -0.81 -13.2309 0.0 0
M  V30 79 O 0.3712 -13.8722 0.0 0
M  V30 80 O -1.9576 -14.176 0.0 0
M  V30 81 O 0.135 -12.0833 0.0 0
M  V30 82 C -2.1939 -12.3871 0.0 0
M  V30 83 C -3.5777 -13.0284 0.0 0
M  V30 84 N -4.9616 -12.1846 0.0 0
M  V30 85 Si 2.1601 -34.0224 0.0 0
M  V30 86 O 3.3414 -34.6637 0.0 0
M  V30 87 O 1.0125 -34.9675 0.0 0
M  V30 88 O 3.1052 -32.8748 0.0 0
M  V30 89 C 0.7763 -33.1786 0.0 0
M  V30 90 C -0.6075 -33.8199 0.0 0
M  V30 91 C -1.9913 -32.9761 0.0 0
M  V30 92 N -3.3752 -33.6174 0.0 0
M  V30 93 C -4.759 -32.7736 0.0 0
M  V30 94 C -3.4765 -35.0012 0.0 0
M  V30 95 Si 0.54 7.2905 0.0 0
M  V30 96 O 1.7213 6.6492 0.0 0
M  V30 97 O -0.6075 6.3454 0.0 0
M  V30 98 O 1.4851 8.4381 0.0 0
M  V30 99 C -0.8438 8.1343 0.0 0
M  V30 100 C -2.2276 7.493 0.0 0
M  V30 101 C -3.6115 8.3368 0.0 0
M  V30 102 N -4.9953 7.6955 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 14 15
M  V30 14 1 14 16
M  V30 15 1 14 17
M  V30 16 1 14 18
M  V30 17 1 15 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 26 27
M  V30 26 1 27 28
M  V30 27 1 27 29
M  V30 28 1 30 31
M  V30 29 1 30 32
M  V30 30 1 30 33
M  V30 31 1 30 34
M  V30 32 1 31 35
M  V30 33 1 32 36
M  V30 34 1 33 37
M  V30 35 1 34 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 1 37 41
M  V30 39 1 38 42
M  V30 40 1 42 43
M  V30 41 1 44 45
M  V30 42 1 44 46
M  V30 43 1 44 47
M  V30 44 1 44 48
M  V30 45 1 45 49
M  V30 46 1 46 50
M  V30 47 1 47 51
M  V30 48 1 48 52
M  V30 49 1 52 53
M  V30 50 1 54 55
M  V30 51 1 54 56
M  V30 52 1 54 57
M  V30 53 1 54 58
M  V30 54 1 55 59
M  V30 55 1 56 60
M  V30 56 1 57 61
M  V30 57 1 58 62
M  V30 58 1 62 63
M  V30 59 1 63 64
M  V30 60 1 64 65
M  V30 61 1 64 66
M  V30 62 1 67 68
M  V30 63 1 67 69
M  V30 64 1 67 70
M  V30 65 1 67 71
M  V30 66 1 68 72
M  V30 67 1 69 73
M  V30 68 1 70 74
M  V30 69 1 71 75
M  V30 70 1 75 76
M  V30 71 1 76 77
M  V30 72 1 78 79
M  V30 73 1 78 80
M  V30 74 1 78 81
M  V30 75 1 78 82
M  V30 76 1 82 83
M  V30 77 1 83 84
M  V30 78 1 85 86
M  V30 79 1 85 87
M  V30 80 1 85 88
M  V30 81 1 85 89
M  V30 82 1 89 90
M  V30 83 1 90 91
M  V30 84 1 91 92
M  V30 85 1 92 93
M  V30 86 1 92 94
M  V30 87 1 95 96
M  V30 88 1 95 97
M  V30 89 1 95 98
M  V30 90 1 95 99
M  V30 91 1 99 100
M  V30 92 1 100 101
M  V30 93 1 101 102
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000748A1-20220106-C00001

>  <Row No>
660

$$$$
US20220000748A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 135 128 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.1195 -0.5597 0.0 0
M  V30 3 O -1.2314 -0.8956 0.0 0
M  V30 4 O 0.8956 1.2314 0.0 0
M  V30 5 C -1.4553 0.8956 0.0 0
M  V30 6 C 2.239 0.3358 0.0 0
M  V30 7 C -0.6717 -2.0151 0.0 0
M  V30 8 C -0.3358 2.4629 0.0 0
M  V30 9 C -2.9107 0.3358 0.0 0
M  V30 10 C 3.3585 -0.2239 0.0 0
M  V30 11 C 0.6157 -1.4553 0.0 0
M  V30 12 C -1.9591 2.239 0.0 0
M  V30 13 N -4.3661 1.2314 0.0 0
M  V30 14 C -5.8214 0.6717 0.0 0
M  V30 15 C -4.534 2.9107 0.0 0
M  V30 16 Si -3.1346 -56.4237 0.0 0
M  V30 17 O -4.8699 -57.0394 0.0 0
M  V30 18 O -4.0302 -54.9683 0.0 0
M  V30 19 O -2.7987 -57.5432 0.0 0
M  V30 20 C -2.0151 -55.5281 0.0 0
M  V30 21 C -6.3252 -56.1438 0.0 0
M  V30 22 C -3.8063 -53.345 0.0 0
M  V30 23 C -1.4553 -57.3753 0.0 0
M  V30 24 C -0.8956 -56.0878 0.0 0
M  V30 25 C -7.7806 -56.7036 0.0 0
M  V30 26 C -2.4629 -53.1771 0.0 0
M  V30 27 C -0.8956 -58.4948 0.0 0
M  V30 28 C 0.2239 -55.1922 0.0 0
M  V30 29 N 1.3434 -55.752 0.0 0
M  V30 30 C 2.4629 -54.8564 0.0 0
M  V30 31 C 1.1754 -57.0954 0.0 0
M  V30 32 C 3.5824 -55.4161 0.0 0
M  V30 33 C 4.7019 -54.5205 0.0 0
M  V30 34 Si 5.8214 -55.0803 0.0 0
M  V30 35 O 4.59 -55.9759 0.0 0
M  V30 36 O 6.7171 -53.8488 0.0 0
M  V30 37 O 6.941 -55.64 0.0 0
M  V30 38 C 4.422 -57.3193 0.0 0
M  V30 39 C 5.4856 -52.6173 0.0 0
M  V30 40 C 8.2844 -55.4721 0.0 0
M  V30 41 C 5.7095 -57.5432 0.0 0
M  V30 42 C 6.3812 -51.3859 0.0 0
M  V30 43 C 9.18 -54.2406 0.0 0
M  V30 44 Si -3.1346 -35.8245 0.0 0
M  V30 45 O -4.8699 -36.4403 0.0 0
M  V30 46 O -4.0302 -34.3692 0.0 0
M  V30 47 O -2.7987 -36.9441 0.0 0
M  V30 48 C -2.0151 -34.9289 0.0 0
M  V30 49 C -6.3252 -35.5447 0.0 0
M  V30 50 C -3.8063 -32.7459 0.0 0
M  V30 51 C -1.4553 -36.7761 0.0 0
M  V30 52 C -0.8956 -35.4887 0.0 0
M  V30 53 C -7.7806 -36.1044 0.0 0
M  V30 54 C -2.4629 -32.5779 0.0 0
M  V30 55 C -0.8956 -37.8957 0.0 0
M  V30 56 C 0.2239 -34.5931 0.0 0
M  V30 57 N 1.3434 -35.1528 0.0 0
M  V30 58 C 2.4629 -34.2572 0.0 0
M  V30 59 C 3.5824 -34.817 0.0 0
M  V30 60 C 4.7019 -33.9214 0.0 0
M  V30 61 Si 5.8214 -34.4811 0.0 0
M  V30 62 O 4.59 -35.3767 0.0 0
M  V30 63 O 6.7171 -33.2497 0.0 0
M  V30 64 O 6.941 -35.0409 0.0 0
M  V30 65 C 4.422 -36.7202 0.0 0
M  V30 66 C 5.4856 -32.0182 0.0 0
M  V30 67 C 8.2844 -34.873 0.0 0
M  V30 68 C 5.7095 -36.9441 0.0 0
M  V30 69 C 6.3812 -30.7867 0.0 0
M  V30 70 C 9.18 -33.6415 0.0 0
M  V30 71 Si -2.239 -8.0605 0.0 0
M  V30 72 O -1.1195 -8.6202 0.0 0
M  V30 73 O -3.4705 -8.9561 0.0 0
M  V30 74 O -1.3434 -6.829 0.0 0
M  V30 75 C -3.6944 -7.1649 0.0 0
M  V30 76 C 0.0 -7.7246 0.0 0
M  V30 77 C -2.9107 -10.0756 0.0 0
M  V30 78 C -2.5748 -5.5975 0.0 0
M  V30 79 C -5.1497 -7.7246 0.0 0
M  V30 80 C 1.1195 -8.2844 0.0 0
M  V30 81 N -6.6051 -6.829 0.0 0
M  V30 82 C -8.0605 -7.3888 0.0 0
M  V30 83 C -6.773 -5.1497 0.0 0
M  V30 84 Si 5.8214 -45.6763 0.0 0
M  V30 85 O 4.59 -46.5719 0.0 0
M  V30 86 O 6.941 -46.2361 0.0 0
M  V30 87 O 6.7171 -44.4448 0.0 0
M  V30 88 C 4.3661 -44.7807 0.0 0
M  V30 89 C 4.422 -47.9153 0.0 0
M  V30 90 C 8.2844 -46.0681 0.0 0
M  V30 91 C 5.4856 -43.2134 0.0 0
M  V30 92 C 2.9107 -45.3405 0.0 0
M  V30 93 C 1.4553 -44.4448 0.0 0
M  V30 94 N 0.0 -45.0046 0.0 0
M  V30 95 C -1.4553 -44.109 0.0 0
M  V30 96 C -0.1679 -46.348 0.0 0
M  V30 97 C -2.9107 -44.6687 0.0 0
M  V30 98 C -4.3661 -43.7731 0.0 0
M  V30 99 Si -5.8214 -44.3329 0.0 0
M  V30 100 O -6.7171 -42.8775 0.0 0
M  V30 101 O -5.4856 -45.4524 0.0 0
M  V30 102 O -7.5567 -44.9486 0.0 0
M  V30 103 C -6.4932 -41.2542 0.0 0
M  V30 104 C -4.1422 -45.2845 0.0 0
M  V30 105 C -9.0121 -44.053 0.0 0
M  V30 106 Si 6.7171 -24.6294 0.0 0
M  V30 107 O 5.4856 -25.525 0.0 0
M  V30 108 O 7.8366 -25.1891 0.0 0
M  V30 109 O 7.6127 -23.3979 0.0 0
M  V30 110 C 5.2617 -23.7337 0.0 0
M  V30 111 C 5.3177 -26.8684 0.0 0
M  V30 112 C 9.18 -25.0212 0.0 0
M  V30 113 C 6.3812 -22.1664 0.0 0
M  V30 114 C 3.8063 -24.2935 0.0 0
M  V30 115 C 2.3509 -23.3979 0.0 0
M  V30 116 N 0.8956 -23.9576 0.0 0
M  V30 117 C -0.5597 -23.062 0.0 0
M  V30 118 C -2.0151 -23.6218 0.0 0
M  V30 119 C -3.4705 -22.7262 0.0 0
M  V30 120 Si -4.9258 -23.2859 0.0 0
M  V30 121 O -5.8214 -21.8306 0.0 0
M  V30 122 O -4.59 -24.4055 0.0 0
M  V30 123 O -6.6611 -23.9017 0.0 0
M  V30 124 C -5.5975 -20.2073 0.0 0
M  V30 125 C -3.2466 -24.2375 0.0 0
M  V30 126 C -8.1165 -23.0061 0.0 0
M  V30 127 Si -0.8956 -16.5688 0.0 0
M  V30 128 O 0.2239 -17.1286 0.0 0
M  V30 129 O -2.127 -17.4644 0.0 0
M  V30 130 O 0.0 -15.3374 0.0 0
M  V30 131 C -2.3509 -15.6732 0.0 0
M  V30 132 C -3.8063 -16.233 0.0 0
M  V30 133 N -5.2617 -15.3374 0.0 0
M  V30 134 C -6.7171 -15.8971 0.0 0
M  V30 135 C -5.4296 -13.6581 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 15 1 16 17
M  V30 16 1 16 18
M  V30 17 1 16 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 28 29
M  V30 28 1 29 30
M  V30 29 1 29 31
M  V30 30 1 30 32
M  V30 31 1 32 33
M  V30 32 1 33 34
M  V30 33 1 34 35
M  V30 34 1 34 36
M  V30 35 1 34 37
M  V30 36 1 35 38
M  V30 37 1 36 39
M  V30 38 1 37 40
M  V30 39 1 38 41
M  V30 40 1 39 42
M  V30 41 1 40 43
M  V30 42 1 44 45
M  V30 43 1 44 46
M  V30 44 1 44 47
M  V30 45 1 44 48
M  V30 46 1 45 49
M  V30 47 1 46 50
M  V30 48 1 47 51
M  V30 49 1 48 52
M  V30 50 1 49 53
M  V30 51 1 50 54
M  V30 52 1 51 55
M  V30 53 1 52 56
M  V30 54 1 56 57
M  V30 55 1 57 58
M  V30 56 1 58 59
M  V30 57 1 59 60
M  V30 58 1 60 61
M  V30 59 1 61 62
M  V30 60 1 61 63
M  V30 61 1 61 64
M  V30 62 1 62 65
M  V30 63 1 63 66
M  V30 64 1 64 67
M  V30 65 1 65 68
M  V30 66 1 66 69
M  V30 67 1 67 70
M  V30 68 1 71 72
M  V30 69 1 71 73
M  V30 70 1 71 74
M  V30 71 1 71 75
M  V30 72 1 72 76
M  V30 73 1 73 77
M  V30 74 1 74 78
M  V30 75 1 75 79
M  V30 76 1 76 80
M  V30 77 1 79 81
M  V30 78 1 81 82
M  V30 79 1 81 83
M  V30 80 1 84 85
M  V30 81 1 84 86
M  V30 82 1 84 87
M  V30 83 1 84 88
M  V30 84 1 85 89
M  V30 85 1 86 90
M  V30 86 1 87 91
M  V30 87 1 88 92
M  V30 88 1 92 93
M  V30 89 1 93 94
M  V30 90 1 94 95
M  V30 91 1 94 96
M  V30 92 1 95 97
M  V30 93 1 97 98
M  V30 94 1 98 99
M  V30 95 1 99 100
M  V30 96 1 99 101
M  V30 97 1 99 102
M  V30 98 1 100 103
M  V30 99 1 101 104
M  V30 100 1 102 105
M  V30 101 1 106 107
M  V30 102 1 106 108
M  V30 103 1 106 109
M  V30 104 1 106 110
M  V30 105 1 107 111
M  V30 106 1 108 112
M  V30 107 1 109 113
M  V30 108 1 110 114
M  V30 109 1 114 115
M  V30 110 1 115 116
M  V30 111 1 116 117
M  V30 112 1 117 118
M  V30 113 1 118 119
M  V30 114 1 119 120
M  V30 115 1 120 121
M  V30 116 1 120 122
M  V30 117 1 120 123
M  V30 118 1 121 124
M  V30 119 1 122 125
M  V30 120 1 123 126
M  V30 121 1 127 128
M  V30 122 1 127 129
M  V30 123 1 127 130
M  V30 124 1 127 131
M  V30 125 1 131 132
M  V30 126 1 132 133
M  V30 127 1 133 134
M  V30 128 1 133 135
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021002.cdx

>  <name>
US20220000748A1-20220106-C00002

>  <Row No>
661

$$$$
US20220000748A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 179 173 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.69 -0.6394 0.0 0
M  V30 3 O -0.8678 1.4616 0.0 0
M  V30 4 O 0.3654 -1.1875 0.0 0
M  V30 5 C 1.1875 0.8678 0.0 0
M  V30 6 C -3.1516 0.2283 0.0 0
M  V30 7 C -0.5937 3.0603 0.0 0
M  V30 8 C 1.7356 -1.0505 0.0 0
M  V30 9 C 2.3751 0.274 0.0 0
M  V30 10 C -4.6133 -0.3654 0.0 0
M  V30 11 C 0.7764 3.1973 0.0 0
M  V30 12 C 2.3294 -2.2381 0.0 0
M  V30 13 C 3.5627 1.1419 0.0 0
M  V30 14 N 4.7503 0.5481 0.0 0
M  V30 15 C 4.6133 -0.8221 0.0 0
M  V30 16 C 5.9379 1.4159 0.0 0
M  V30 17 C 5.8008 -1.4159 0.0 0
M  V30 18 C 7.1255 0.8221 0.0 0
M  V30 19 O 5.6638 -2.7862 0.0 0
M  V30 20 C 8.313 1.69 0.0 0
M  V30 21 Si 9.5006 1.0962 0.0 0
M  V30 22 O 8.313 0.1827 0.0 0
M  V30 23 O 10.4141 2.2838 0.0 0
M  V30 24 O 10.6882 0.5024 0.0 0
M  V30 25 C 8.176 -1.1875 0.0 0
M  V30 26 C 9.2266 3.4713 0.0 0
M  V30 27 C 12.0585 0.6394 0.0 0
M  V30 28 C 9.5006 -1.4616 0.0 0
M  V30 29 C 10.1401 4.6589 0.0 0
M  V30 30 C 12.972 1.827 0.0 0
M  V30 31 Si -2.1924 -46.0417 0.0 0
M  V30 32 O -3.8824 -46.6811 0.0 0
M  V30 33 O -3.0603 -44.58 0.0 0
M  V30 34 O -1.827 -47.2293 0.0 0
M  V30 35 C -1.0048 -45.1738 0.0 0
M  V30 36 C -5.3441 -45.8133 0.0 0
M  V30 37 C -2.7862 -42.9814 0.0 0
M  V30 38 C -0.4567 -47.0922 0.0 0
M  V30 39 C 0.1827 -45.7676 0.0 0
M  V30 40 C -6.8057 -46.4071 0.0 0
M  V30 41 C -1.4159 -42.8443 0.0 0
M  V30 42 C 0.137 -48.2798 0.0 0
M  V30 43 C 1.3702 -44.8998 0.0 0
M  V30 44 N 2.5578 -45.4936 0.0 0
M  V30 45 C 2.4208 -46.8638 0.0 0
M  V30 46 C 3.7454 -44.6257 0.0 0
M  V30 47 C 3.7454 -47.1379 0.0 0
M  V30 48 C 4.933 -45.2195 0.0 0
M  V30 49 N 3.6084 -48.5082 0.0 0
M  V30 50 C 6.1206 -44.3517 0.0 0
M  V30 51 Si 7.3082 -44.9454 0.0 0
M  V30 52 O 6.1206 -45.859 0.0 0
M  V30 53 O 8.2217 -43.7579 0.0 0
M  V30 54 O 8.4957 -45.5392 0.0 0
M  V30 55 C 5.9835 -47.2293 0.0 0
M  V30 56 C 7.0341 -42.5703 0.0 0
M  V30 57 C 9.866 -45.4022 0.0 0
M  V30 58 C 7.3082 -47.5033 0.0 0
M  V30 59 C 7.9476 -41.3827 0.0 0
M  V30 60 C 10.7796 -44.2146 0.0 0
M  V30 61 Si -1.0962 -22.29 0.0 0
M  V30 62 O -2.7862 -22.9295 0.0 0
M  V30 63 O -1.964 -20.8283 0.0 0
M  V30 64 O -0.7308 -23.4776 0.0 0
M  V30 65 C 0.0913 -21.4221 0.0 0
M  V30 66 C -4.2478 -22.0616 0.0 0
M  V30 67 C -1.69 -19.2297 0.0 0
M  V30 68 C -1.9184 -24.3911 0.0 0
M  V30 69 C 1.2789 -22.0159 0.0 0
M  V30 70 C -5.8465 -22.3357 0.0 0
M  V30 71 C -0.3197 -19.0926 0.0 0
M  V30 72 C -1.6443 -25.7157 0.0 0
M  V30 73 C 2.4665 -21.1481 0.0 0
M  V30 74 N 3.6541 -21.7419 0.0 0
M  V30 75 C 4.8416 -20.874 0.0 0
M  V30 76 C 3.517 -23.1122 0.0 0
M  V30 77 C 6.0292 -21.4678 0.0 0
M  V30 78 C 4.7046 -23.706 0.0 0
M  V30 79 C 7.2168 -20.6 0.0 0
M  V30 80 C 4.5676 -25.0762 0.0 0
M  V30 81 Si 8.4044 -21.1938 0.0 0
M  V30 82 Si 3.1059 -25.67 0.0 0
M  V30 83 O 9.3179 -20.0062 0.0 0
M  V30 84 O 9.592 -21.7876 0.0 0
M  V30 85 O 7.2168 -22.1073 0.0 0
M  V30 86 O 1.6443 -26.2638 0.0 0
M  V30 87 O 4.2935 -26.2638 0.0 0
M  V30 88 O 1.6443 -24.8022 0.0 0
M  V30 89 C 8.1303 -18.8186 0.0 0
M  V30 90 C 10.9623 -21.6505 0.0 0
M  V30 91 C 7.0798 -23.4776 0.0 0
M  V30 92 C 0.1827 -25.396 0.0 0
M  V30 93 C 5.6181 -25.7157 0.0 0
M  V30 94 C 1.5073 -23.1578 0.0 0
M  V30 95 C 6.5317 -19.0926 0.0 0
M  V30 96 C 11.2363 -20.0519 0.0 0
M  V30 97 C 8.4501 -23.3405 0.0 0
M  V30 98 C -1.0048 -26.3095 0.0 0
M  V30 99 C 6.5317 -26.6292 0.0 0
M  V30 100 C 0.0456 -22.29 0.0 0
M  V30 101 Si 8.039 11.3277 0.0 0
M  V30 102 O 6.8514 10.4141 0.0 0
M  V30 103 O 9.2266 10.7339 0.0 0
M  V30 104 O 8.9525 12.5153 0.0 0
M  V30 105 C 6.5773 12.1955 0.0 0
M  V30 106 C 6.7144 9.0439 0.0 0
M  V30 107 C 10.5969 10.8709 0.0 0
M  V30 108 C 7.7649 13.7028 0.0 0
M  V30 109 C 5.1157 11.6017 0.0 0
M  V30 110 C 3.6541 12.4696 0.0 0
M  V30 111 N 2.1924 11.8758 0.0 0
M  V30 112 C 2.0554 10.5055 0.0 0
M  V30 113 C 0.7308 12.7436 0.0 0
M  V30 114 C 3.38 10.2314 0.0 0
M  V30 115 C -0.7308 12.1498 0.0 0
M  V30 116 O 3.243 8.8612 0.0 0
M  V30 117 C -2.1924 13.0177 0.0 0
M  V30 118 Si -3.6541 12.4239 0.0 0
M  V30 119 O -4.5219 13.8855 0.0 0
M  V30 120 O -3.2886 11.2363 0.0 0
M  V30 121 O -5.3441 11.7844 0.0 0
M  V30 122 C -4.2478 15.4842 0.0 0
M  V30 123 C -1.9184 11.3734 0.0 0
M  V30 124 C -6.8057 12.6523 0.0 0
M  V30 125 Si 8.039 -36.1756 0.0 0
M  V30 126 O 6.8514 -37.0891 0.0 0
M  V30 127 O 9.2266 -36.7694 0.0 0
M  V30 128 O 8.9525 -34.988 0.0 0
M  V30 129 C 6.5773 -35.3077 0.0 0
M  V30 130 C 6.7144 -38.4594 0.0 0
M  V30 131 C 10.5969 -36.6324 0.0 0
M  V30 132 C 7.7649 -33.8004 0.0 0
M  V30 133 C 5.1157 -35.9015 0.0 0
M  V30 134 C 3.6541 -35.0337 0.0 0
M  V30 135 N 2.1924 -35.6275 0.0 0
M  V30 136 C 2.0554 -36.9978 0.0 0
M  V30 137 C 0.7308 -34.7596 0.0 0
M  V30 138 C 3.38 -37.2718 0.0 0
M  V30 139 C -0.7308 -35.3534 0.0 0
M  V30 140 N 3.243 -38.6421 0.0 0
M  V30 141 C -2.1924 -34.4856 0.0 0
M  V30 142 Si -3.6541 -35.0794 0.0 0
M  V30 143 O -4.5219 -33.6177 0.0 0
M  V30 144 O -3.2886 -36.2669 0.0 0
M  V30 145 O -5.3441 -35.7188 0.0 0
M  V30 146 C -4.2478 -32.019 0.0 0
M  V30 147 C -1.9184 -36.1299 0.0 0
M  V30 148 C -6.8057 -34.851 0.0 0
M  V30 149 Si 8.4044 -9.866 0.0 0
M  V30 150 O 7.2168 -10.7796 0.0 0
M  V30 151 O 9.592 -10.4598 0.0 0
M  V30 152 O 9.3179 -8.6784 0.0 0
M  V30 153 C 6.9427 -8.9982 0.0 0
M  V30 154 C 7.0798 -12.1498 0.0 0
M  V30 155 C 10.9623 -10.3228 0.0 0
M  V30 156 C 8.1303 -7.4909 0.0 0
M  V30 157 C 5.4811 -9.592 0.0 0
M  V30 158 C 4.0195 -8.7241 0.0 0
M  V30 159 N 2.5578 -9.3179 0.0 0
M  V30 160 C 1.0962 -8.4501 0.0 0
M  V30 161 C 2.4208 -10.6882 0.0 0
M  V30 162 C -0.3654 -9.0439 0.0 0
M  V30 163 C 3.6084 -11.282 0.0 0
M  V30 164 C -1.827 -8.176 0.0 0
M  V30 165 C 3.4713 -12.6523 0.0 0
M  V30 166 Si -3.2886 -8.7698 0.0 0
M  V30 167 Si 2.0097 -13.2461 0.0 0
M  V30 168 O -4.1565 -7.3082 0.0 0
M  V30 169 O -2.9232 -9.9574 0.0 0
M  V30 170 O -4.9787 -9.4093 0.0 0
M  V30 171 O 0.5481 -12.3782 0.0 0
M  V30 172 O 0.5481 -13.8399 0.0 0
M  V30 173 O 3.1973 -13.8399 0.0 0
M  V30 174 C -3.8824 -5.7095 0.0 0
M  V30 175 C -1.5529 -9.8204 0.0 0
M  V30 176 C -6.4403 -8.5414 0.0 0
M  V30 177 C 0.411 -10.7339 0.0 0
M  V30 178 C -0.9135 -12.972 0.0 0
M  V30 179 C 4.5219 -13.2918 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 46 48
M  V30 47 1 47 49
M  V30 48 1 48 50
M  V30 49 1 50 51
M  V30 50 1 51 52
M  V30 51 1 51 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 56 59
M  V30 58 1 57 60
M  V30 59 1 61 62
M  V30 60 1 61 63
M  V30 61 1 61 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 68 72
M  V30 70 1 69 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 74 76
M  V30 74 1 75 77
M  V30 75 1 76 78
M  V30 76 1 77 79
M  V30 77 1 78 80
M  V30 78 1 79 81
M  V30 79 1 80 82
M  V30 80 1 81 83
M  V30 81 1 81 84
M  V30 82 1 81 85
M  V30 83 1 82 86
M  V30 84 1 82 87
M  V30 85 1 82 88
M  V30 86 1 83 89
M  V30 87 1 84 90
M  V30 88 1 85 91
M  V30 89 1 86 92
M  V30 90 1 87 93
M  V30 91 1 88 94
M  V30 92 1 89 95
M  V30 93 1 90 96
M  V30 94 1 91 97
M  V30 95 1 92 98
M  V30 96 1 93 99
M  V30 97 1 94 100
M  V30 98 1 101 102
M  V30 99 1 101 103
M  V30 100 1 101 104
M  V30 101 1 101 105
M  V30 102 1 102 106
M  V30 103 1 103 107
M  V30 104 1 104 108
M  V30 105 1 105 109
M  V30 106 1 109 110
M  V30 107 1 110 111
M  V30 108 1 111 112
M  V30 109 1 111 113
M  V30 110 1 112 114
M  V30 111 1 113 115
M  V30 112 1 114 116
M  V30 113 1 115 117
M  V30 114 1 117 118
M  V30 115 1 118 119
M  V30 116 1 118 120
M  V30 117 1 118 121
M  V30 118 1 119 122
M  V30 119 1 120 123
M  V30 120 1 121 124
M  V30 121 1 125 126
M  V30 122 1 125 127
M  V30 123 1 125 128
M  V30 124 1 125 129
M  V30 125 1 126 130
M  V30 126 1 127 131
M  V30 127 1 128 132
M  V30 128 1 129 133
M  V30 129 1 133 134
M  V30 130 1 134 135
M  V30 131 1 135 136
M  V30 132 1 135 137
M  V30 133 1 136 138
M  V30 134 1 137 139
M  V30 135 1 138 140
M  V30 136 1 139 141
M  V30 137 1 141 142
M  V30 138 1 142 143
M  V30 139 1 142 144
M  V30 140 1 142 145
M  V30 141 1 143 146
M  V30 142 1 144 147
M  V30 143 1 145 148
M  V30 144 1 149 150
M  V30 145 1 149 151
M  V30 146 1 149 152
M  V30 147 1 149 153
M  V30 148 1 150 154
M  V30 149 1 151 155
M  V30 150 1 152 156
M  V30 151 1 153 157
M  V30 152 1 157 158
M  V30 153 1 158 159
M  V30 154 1 159 160
M  V30 155 1 159 161
M  V30 156 1 160 162
M  V30 157 1 161 163
M  V30 158 1 162 164
M  V30 159 1 163 165
M  V30 160 1 164 166
M  V30 161 1 165 167
M  V30 162 1 166 168
M  V30 163 1 166 169
M  V30 164 1 166 170
M  V30 165 1 167 171
M  V30 166 1 167 172
M  V30 167 1 167 173
M  V30 168 1 168 174
M  V30 169 1 169 175
M  V30 170 1 170 176
M  V30 171 1 171 177
M  V30 172 1 172 178
M  V30 173 1 173 179
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021003.cdx

>  <name>
US20220000748A1-20220106-C00003

>  <Row No>
662

$$$$
US20220000748A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 54 52 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 0.451 -1.2573 0.0 0
M  V30 3 O -1.6127 -0.7243 0.0 0
M  V30 4 O -0.8063 1.3393 0.0 0
M  V30 5 C 1.2573 0.8063 0.0 0
M  V30 6 C 1.9133 -1.2163 0.0 0
M  V30 7 C -2.952 0.082 0.0 0
M  V30 8 C -0.451 2.829 0.0 0
M  V30 9 C 2.5147 0.082 0.0 0
M  V30 10 C 2.6377 -2.4737 0.0 0
M  V30 11 C -4.2914 -0.6423 0.0 0
M  V30 12 C 1.0113 2.87 0.0 0
M  V30 13 C 3.772 0.8883 0.0 0
M  V30 14 N 5.0294 0.164 0.0 0
M  V30 15 C 4.9884 -1.2983 0.0 0
M  V30 16 C 6.2868 0.9703 0.0 0
M  V30 17 C 6.3961 -1.6537 0.0 0
M  V30 18 C 7.5441 0.246 0.0 0
M  V30 19 C 6.3551 -3.116 0.0 0
M  V30 20 C 8.8015 1.0523 0.0 0
M  V30 21 Si 10.0589 0.328 0.0 0
M  V30 22 O 8.9655 -0.6833 0.0 0
M  V30 23 O 11.0702 1.4213 0.0 0
M  V30 24 O 11.3162 -0.3963 0.0 0
M  V30 25 C 8.9245 -2.1457 0.0 0
M  V30 26 C 9.9769 2.5147 0.0 0
M  V30 27 C 12.7786 -0.3553 0.0 0
M  V30 28 C 10.3322 -2.501 0.0 0
M  V30 29 C 10.9882 3.608 0.0 0
M  V30 30 C 13.79 0.738 0.0 0
M  V30 31 Si 8.6375 13.995 0.0 0
M  V30 32 O 7.5441 12.9836 0.0 0
M  V30 33 O 9.8949 13.2706 0.0 0
M  V30 34 O 9.6489 15.0883 0.0 0
M  V30 35 C 7.2981 14.8013 0.0 0
M  V30 36 C 7.5031 11.5212 0.0 0
M  V30 37 C 11.3572 13.3116 0.0 0
M  V30 38 C 8.5555 16.1817 0.0 0
M  V30 39 C 5.9588 14.077 0.0 0
M  V30 40 C 4.6194 14.8833 0.0 0
M  V30 41 N 3.28 14.159 0.0 0
M  V30 42 C 3.239 12.6966 0.0 0
M  V30 43 C 1.9407 14.9653 0.0 0
M  V30 44 C 4.6467 12.3413 0.0 0
M  V30 45 C 0.6013 14.241 0.0 0
M  V30 46 C 4.6057 10.8789 0.0 0
M  V30 47 C -0.738 15.0473 0.0 0
M  V30 48 Si -2.0773 14.323 0.0 0
M  V30 49 O -2.8837 15.6623 0.0 0
M  V30 50 O -1.6263 13.0656 0.0 0
M  V30 51 O -3.69 13.5986 0.0 0
M  V30 52 C -2.5283 17.152 0.0 0
M  V30 53 C -0.164 13.1066 0.0 0
M  V30 54 C -5.0294 14.405 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 39 40
M  V30 39 1 40 41
M  V30 40 1 41 42
M  V30 41 1 41 43
M  V30 42 1 42 44
M  V30 43 1 43 45
M  V30 44 2 44 46
M  V30 45 1 45 47
M  V30 46 1 47 48
M  V30 47 1 48 49
M  V30 48 1 48 50
M  V30 49 1 48 51
M  V30 50 1 49 52
M  V30 51 1 50 53
M  V30 52 1 51 54
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021004.cdx

>  <name>
US20220000748A1-20220106-C00004

>  <Row No>
663

$$$$
US20220000748A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 140 130 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 0.8808 1.2111 0.0 0
M  V30 3 O -1.2111 -0.8808 0.0 0
M  V30 4 O 1.101 -0.5505 0.0 0
M  V30 5 C -1.4314 0.8808 0.0 0
M  V30 6 C -0.3303 2.4223 0.0 0
M  V30 7 C -0.6606 -1.9819 0.0 0
M  V30 8 C 2.2021 0.3303 0.0 0
M  V30 9 C -2.8628 0.3303 0.0 0
M  V30 10 C 0.2202 3.8538 0.0 0
M  V30 11 C 0.6055 -1.4314 0.0 0
M  V30 12 C -4.2942 1.2111 0.0 0
M  V30 13 C -5.7256 0.6606 0.0 0
M  V30 14 C -7.157 1.5415 0.0 0
M  V30 15 C -8.5884 0.9909 0.0 0
M  V30 16 C -10.0199 1.8718 0.0 0
M  V30 17 C -11.4513 1.3213 0.0 0
M  V30 18 C -12.8827 2.2021 0.0 0
M  V30 19 C -14.3141 1.6516 0.0 0
M  V30 20 C -15.7455 2.5325 0.0 0
M  V30 21 C -17.1769 1.9819 0.0 0
M  V30 22 Si -6.6065 17.6174 0.0 0
M  V30 23 O -7.8177 16.7365 0.0 0
M  V30 24 O -5.7256 18.8286 0.0 0
M  V30 25 O -5.5054 17.0668 0.0 0
M  V30 26 C -8.0379 18.4982 0.0 0
M  V30 27 C -7.2671 15.6354 0.0 0
M  V30 28 C -6.9368 20.0398 0.0 0
M  V30 29 C -4.4043 17.9477 0.0 0
M  V30 30 C -9.4693 17.9477 0.0 0
M  V30 31 C -6.0009 16.1859 0.0 0
M  V30 32 C -6.0559 21.251 0.0 0
M  V30 33 C -10.9007 18.8286 0.0 0
M  V30 34 C -12.3321 18.278 0.0 0
M  V30 35 C -13.7636 19.1589 0.0 0
M  V30 36 C -15.195 18.6083 0.0 0
M  V30 37 C -16.6264 19.4892 0.0 0
M  V30 38 C -18.0578 18.9387 0.0 0
M  V30 39 Si -8.8087 32.1517 0.0 0
M  V30 40 O -7.9278 33.3629 0.0 0
M  V30 41 O -10.0199 31.2709 0.0 0
M  V30 42 O -7.7076 31.6012 0.0 0
M  V30 43 C -10.2401 33.0326 0.0 0
M  V30 44 C -9.139 34.5741 0.0 0
M  V30 45 C -9.4693 30.1698 0.0 0
M  V30 46 C -6.6065 32.482 0.0 0
M  V30 47 C -11.6715 32.482 0.0 0
M  V30 48 C -8.2581 35.7853 0.0 0
M  V30 49 C -8.2031 30.7203 0.0 0
M  V30 50 C -13.1029 33.3629 0.0 0
M  V30 51 C -14.5343 32.8124 0.0 0
M  V30 52 C -15.9657 33.6932 0.0 0
M  V30 53 C -17.3971 33.1427 0.0 0
M  V30 54 Si -3.083 9.6895 0.0 0
M  V30 55 O -2.2572 10.8457 0.0 0
M  V30 56 O -4.2391 8.8637 0.0 0
M  V30 57 O -2.037 9.139 0.0 0
M  V30 58 C -4.4594 10.5704 0.0 0
M  V30 59 C -3.4133 12.0018 0.0 0
M  V30 60 C -3.6886 7.8177 0.0 0
M  V30 61 C -0.9909 10.0199 0.0 0
M  V30 62 C -5.8357 10.0199 0.0 0
M  V30 63 C -7.2121 10.9007 0.0 0
M  V30 64 C -8.5884 10.3502 0.0 0
M  V30 65 C -9.9648 11.231 0.0 0
M  V30 66 C -11.3412 10.6805 0.0 0
M  V30 67 C -12.7175 11.5614 0.0 0
M  V30 68 C -14.0939 11.0108 0.0 0
M  V30 69 C -15.4702 11.8917 0.0 0
M  V30 70 C -16.8466 11.3412 0.0 0
M  V30 71 C -18.223 12.222 0.0 0
M  V30 72 C -19.5993 11.6715 0.0 0
M  V30 73 Si -6.6065 25.9856 0.0 0
M  V30 74 O -5.7256 27.1968 0.0 0
M  V30 75 O -7.8177 25.1048 0.0 0
M  V30 76 O -5.5054 25.4351 0.0 0
M  V30 77 C -8.0379 26.8665 0.0 0
M  V30 78 C -6.9368 28.408 0.0 0
M  V30 79 C -7.2671 24.0037 0.0 0
M  V30 80 C -4.4043 26.316 0.0 0
M  V30 81 C -9.4693 26.316 0.0 0
M  V30 82 C -10.9007 27.1968 0.0 0
M  V30 83 C -12.3321 26.6463 0.0 0
M  V30 84 C -13.7636 27.5272 0.0 0
M  V30 85 C -15.195 26.9766 0.0 0
M  V30 86 C -16.6264 27.8575 0.0 0
M  V30 87 C -18.0578 27.3069 0.0 0
M  V30 88 Si -8.8087 40.0796 0.0 0
M  V30 89 O -7.9278 41.2908 0.0 0
M  V30 90 O -10.0199 39.1987 0.0 0
M  V30 91 O -7.7076 39.529 0.0 0
M  V30 92 C -10.2401 40.9604 0.0 0
M  V30 93 C -9.139 42.502 0.0 0
M  V30 94 C -9.4693 38.0976 0.0 0
M  V30 95 C -6.6065 40.4099 0.0 0
M  V30 96 C -11.6715 40.4099 0.0 0
M  V30 97 C -13.1029 41.2908 0.0 0
M  V30 98 C -14.5343 40.7402 0.0 0
M  V30 99 C -15.9657 41.6211 0.0 0
M  V30 100 C -17.3971 41.0705 0.0 0
M  V30 101 Si -7.4873 48.0074 0.0 0
M  V30 102 O -8.6985 47.1265 0.0 0
M  V30 103 O -6.3863 47.4568 0.0 0
M  V30 104 O -6.6065 49.2186 0.0 0
M  V30 105 C -8.9188 48.8883 0.0 0
M  V30 106 C -8.148 46.0254 0.0 0
M  V30 107 C -5.2852 48.3377 0.0 0
M  V30 108 C -7.8177 50.4298 0.0 0
M  V30 109 C -10.3502 48.3377 0.0 0
M  V30 110 C -6.8267 46.1906 0.0 0
M  V30 111 C -4.1841 47.7872 0.0 0
M  V30 112 C -6.9368 51.641 0.0 0
M  V30 113 Si -14.0939 48.0074 0.0 0
M  V30 114 O -12.9928 47.4568 0.0 0
M  V30 115 O -15.3051 47.1265 0.0 0
M  V30 116 O -13.213 49.2186 0.0 0
M  V30 117 C -15.5253 48.8883 0.0 0
M  V30 118 C -11.8917 48.3377 0.0 0
M  V30 119 C -14.7545 46.0254 0.0 0
M  V30 120 C -14.4242 50.4298 0.0 0
M  V30 121 C -16.9567 48.3377 0.0 0
M  V30 122 Si -7.9278 56.3757 0.0 0
M  V30 123 O -9.139 55.4948 0.0 0
M  V30 124 O -6.8267 55.8251 0.0 0
M  V30 125 O -7.0469 57.5869 0.0 0
M  V30 126 C -9.3592 57.2565 0.0 0
M  V30 127 C -8.5884 54.3937 0.0 0
M  V30 128 C -5.7256 56.706 0.0 0
M  V30 129 C -8.2581 58.7981 0.0 0
M  V30 130 C -7.2671 54.5589 0.0 0
M  V30 131 C -4.6245 56.1554 0.0 0
M  V30 132 C -7.3772 60.0093 0.0 0
M  V30 133 Si -14.0939 56.3757 0.0 0
M  V30 134 O -12.9928 55.8251 0.0 0
M  V30 135 O -15.3051 55.4948 0.0 0
M  V30 136 O -13.213 57.5869 0.0 0
M  V30 137 C -15.5253 57.2565 0.0 0
M  V30 138 C -11.8917 56.706 0.0 0
M  V30 139 C -14.7545 54.3937 0.0 0
M  V30 140 C -14.4242 58.7981 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 9 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 22 23
M  V30 22 1 22 24
M  V30 23 1 22 25
M  V30 24 1 22 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 25 29
M  V30 28 1 26 30
M  V30 29 1 27 31
M  V30 30 1 28 32
M  V30 31 1 30 33
M  V30 32 1 33 34
M  V30 33 1 34 35
M  V30 34 1 35 36
M  V30 35 1 36 37
M  V30 36 1 37 38
M  V30 37 1 39 40
M  V30 38 1 39 41
M  V30 39 1 39 42
M  V30 40 1 39 43
M  V30 41 1 40 44
M  V30 42 1 41 45
M  V30 43 1 42 46
M  V30 44 1 43 47
M  V30 45 1 44 48
M  V30 46 1 45 49
M  V30 47 1 47 50
M  V30 48 1 50 51
M  V30 49 1 51 52
M  V30 50 1 52 53
M  V30 51 1 54 55
M  V30 52 1 54 56
M  V30 53 1 54 57
M  V30 54 1 54 58
M  V30 55 1 55 59
M  V30 56 1 56 60
M  V30 57 1 57 61
M  V30 58 1 58 62
M  V30 59 1 62 63
M  V30 60 1 63 64
M  V30 61 1 64 65
M  V30 62 1 65 66
M  V30 63 1 66 67
M  V30 64 1 67 68
M  V30 65 1 68 69
M  V30 66 1 69 70
M  V30 67 1 70 71
M  V30 68 1 71 72
M  V30 69 1 73 74
M  V30 70 1 73 75
M  V30 71 1 73 76
M  V30 72 1 73 77
M  V30 73 1 74 78
M  V30 74 1 75 79
M  V30 75 1 76 80
M  V30 76 1 77 81
M  V30 77 1 81 82
M  V30 78 1 82 83
M  V30 79 1 83 84
M  V30 80 1 84 85
M  V30 81 1 85 86
M  V30 82 1 86 87
M  V30 83 1 88 89
M  V30 84 1 88 90
M  V30 85 1 88 91
M  V30 86 1 88 92
M  V30 87 1 89 93
M  V30 88 1 90 94
M  V30 89 1 91 95
M  V30 90 1 92 96
M  V30 91 1 96 97
M  V30 92 1 97 98
M  V30 93 1 98 99
M  V30 94 1 99 100
M  V30 95 1 101 102
M  V30 96 1 101 103
M  V30 97 1 101 104
M  V30 98 1 101 105
M  V30 99 1 102 106
M  V30 100 1 103 107
M  V30 101 1 104 108
M  V30 102 1 105 109
M  V30 103 1 106 110
M  V30 104 1 107 111
M  V30 105 1 108 112
M  V30 106 1 113 114
M  V30 107 1 113 115
M  V30 108 1 113 116
M  V30 109 1 113 117
M  V30 110 1 114 118
M  V30 111 1 115 119
M  V30 112 1 116 120
M  V30 113 1 117 121
M  V30 114 1 122 123
M  V30 115 1 122 124
M  V30 116 1 122 125
M  V30 117 1 122 126
M  V30 118 1 123 127
M  V30 119 1 124 128
M  V30 120 1 125 129
M  V30 121 1 127 130
M  V30 122 1 128 131
M  V30 123 1 129 132
M  V30 124 1 133 134
M  V30 125 1 133 135
M  V30 126 1 133 136
M  V30 127 1 133 137
M  V30 128 1 134 138
M  V30 129 1 135 139
M  V30 130 1 136 140
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000748A1-20220106-C00005

>  <Row No>
664

$$$$
US20220000748A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 13 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.7693 -1.29 0.0 0
M  V30 3 N -2.2842 -1.2782 0.0 0
M  V30 4 ? -0.0473 -2.5565 0.0 0
M  V30 5 C -3.7992 -1.2664 0.0 0
M  V30 6 C -5.3142 -1.2545 0.0 0
M  V30 7 N -5.3378 -2.7458 0.0 0 CHG=1 CFG=2
M  V30 8 C -4.1306 -3.6217 0.0 0
M  V30 9 C -6.5924 -3.598 0.0 0
M  V30 10 C -6.8055 -2.3197 0.0 0
M  V30 11 N -4.6277 -5.0183 0.0 0
M  V30 12 ? -2.6393 -3.6098 0.0 0
M  V30 13 C -6.1427 -5.0064 0.0 0
M  V30 14 A 1.5149 -2.3671 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 7 10 CFG=1
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 11 13
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 7)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000748A1-20220106-C00006

>  <Row No>
665

$$$$
US20220000748A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=16
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000748A1-20220106-C00008

>  <Row No>
666

$$$$
US20220000749A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 63 57 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.1198 -0.9954 0.0 0
M  V30 3 O 1.2442 -0.6843 0.0 0
M  V30 4 O 0.9954 1.1198 0.0 0
M  V30 5 C -1.3272 0.8087 0.0 0
M  V30 6 C -0.4354 -2.2396 0.0 0
M  V30 7 C 2.4885 0.1244 0.0 0
M  V30 8 C -0.1244 2.2396 0.0 0
M  V30 9 C -2.6751 0.1244 0.0 0
M  V30 10 C 0.9124 -1.7834 0.0 0
M  V30 11 C 3.7328 -0.5599 0.0 0
M  V30 12 C -1.5968 1.9078 0.0 0
M  V30 13 N -4.0231 0.9332 0.0 0
M  V30 14 Si 0.8295 21.2356 0.0 0
M  V30 15 O -0.2903 20.2402 0.0 0
M  V30 16 O 2.0737 20.5513 0.0 0
M  V30 17 O 1.8249 22.3555 0.0 0
M  V30 18 C -0.4977 22.0444 0.0 0
M  V30 19 C 0.394 18.9959 0.0 0
M  V30 20 C 3.318 21.36 0.0 0
M  V30 21 C 0.705 23.4753 0.0 0
M  V30 22 C -1.8456 21.36 0.0 0
M  V30 23 C 1.7419 19.4522 0.0 0
M  V30 24 C 4.5623 20.6757 0.0 0
M  V30 25 C -0.7673 23.1435 0.0 0
M  V30 26 C -3.1729 22.1688 0.0 0
M  V30 27 N -4.5208 21.4845 0.0 0
M  V30 28 Si 9.9542 0.4977 0.0 0
M  V30 29 O 8.8343 -0.4977 0.0 0
M  V30 30 O 11.1984 -0.1866 0.0 0
M  V30 31 O 10.9496 1.6175 0.0 0
M  V30 32 C 8.6062 1.3064 0.0 0
M  V30 33 C 9.5187 -1.7419 0.0 0
M  V30 34 C 12.4427 0.6221 0.0 0
M  V30 35 C 9.8297 2.7374 0.0 0
M  V30 36 C 7.2582 0.6221 0.0 0
M  V30 37 N 5.9103 1.4309 0.0 0
M  V30 38 Si 0.9954 10.6178 0.0 0
M  V30 39 O -0.1244 9.6224 0.0 0
M  V30 40 O 2.2396 9.9334 0.0 0
M  V30 41 O 1.9908 11.7376 0.0 0
M  V30 42 C -0.3318 11.4266 0.0 0
M  V30 43 C 0.5599 8.3781 0.0 0
M  V30 44 C 3.4839 10.7422 0.0 0
M  V30 45 C 0.8709 12.8575 0.0 0
M  V30 46 C -1.6797 10.7422 0.0 0
M  V30 47 C -3.0277 11.551 0.0 0
M  V30 48 N -4.3757 10.8666 0.0 0
M  V30 49 Si -0.1659 -8.9587 0.0 0
M  V30 50 O 1.0783 -9.6431 0.0 0
M  V30 51 O 0.8295 -7.8389 0.0 0
M  V30 52 O -1.2857 -9.9542 0.0 0
M  V30 53 C -1.4931 -8.15 0.0 0
M  V30 54 C -2.8203 -8.8343 0.0 0
M  V30 55 N -4.1683 -8.0255 0.0 0
M  V30 56 Si 10.7837 10.6178 0.0 0
M  V30 57 O 12.028 9.9334 0.0 0
M  V30 58 O 11.7791 11.7376 0.0 0
M  V30 59 O 9.6638 9.6224 0.0 0
M  V30 60 C 9.4357 11.4266 0.0 0
M  V30 61 C 8.0878 10.7422 0.0 0
M  V30 62 C 6.7398 11.551 0.0 0
M  V30 63 N 5.4126 10.8666 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 14 15
M  V30 14 1 14 16
M  V30 15 1 14 17
M  V30 16 1 14 18
M  V30 17 1 15 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 26 27
M  V30 26 1 28 29
M  V30 27 1 28 30
M  V30 28 1 28 31
M  V30 29 1 28 32
M  V30 30 1 29 33
M  V30 31 1 30 34
M  V30 32 1 31 35
M  V30 33 1 32 36
M  V30 34 1 36 37
M  V30 35 1 38 39
M  V30 36 1 38 40
M  V30 37 1 38 41
M  V30 38 1 38 42
M  V30 39 1 39 43
M  V30 40 1 40 44
M  V30 41 1 41 45
M  V30 42 1 42 46
M  V30 43 1 46 47
M  V30 44 1 47 48
M  V30 45 1 49 50
M  V30 46 1 49 51
M  V30 47 1 49 52
M  V30 48 1 49 53
M  V30 49 1 53 54
M  V30 50 1 54 55
M  V30 51 1 56 57
M  V30 52 1 56 58
M  V30 53 1 56 59
M  V30 54 1 56 60
M  V30 55 1 60 61
M  V30 56 1 61 62
M  V30 57 1 62 63
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000749A1-20220106-C00001

>  <Row No>
667

$$$$
US20220000749A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 75 69 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.1178 -0.9654 0.0 0
M  V30 3 O 1.2194 -0.6605 0.0 0
M  V30 4 O 0.9654 1.1178 0.0 0
M  V30 5 C -1.3718 0.8129 0.0 0
M  V30 6 C -0.4572 -2.1848 0.0 0
M  V30 7 C 2.4389 0.1524 0.0 0
M  V30 8 C -0.1524 2.2356 0.0 0
M  V30 9 C -2.7437 0.1524 0.0 0
M  V30 10 C 0.8891 -1.7275 0.0 0
M  V30 11 C 3.6583 -0.5081 0.0 0
M  V30 12 C -1.6513 1.9308 0.0 0
M  V30 13 N -4.1156 0.9654 0.0 0
M  V30 14 C -5.4875 0.3048 0.0 0
M  V30 15 C -4.1918 2.5151 0.0 0
M  V30 16 Si 0.2032 26.015 0.0 0
M  V30 17 O -0.9145 25.0496 0.0 0
M  V30 18 O 1.4226 25.3544 0.0 0
M  V30 19 O 1.1686 27.1328 0.0 0
M  V30 20 C -1.1686 26.828 0.0 0
M  V30 21 C -0.254 23.8301 0.0 0
M  V30 22 C 2.6421 26.1674 0.0 0
M  V30 23 C 0.0508 28.2506 0.0 0
M  V30 24 C -2.5405 26.1674 0.0 0
M  V30 25 C 1.0924 24.2874 0.0 0
M  V30 26 C 3.8616 25.5069 0.0 0
M  V30 27 C -1.4481 27.9458 0.0 0
M  V30 28 C -3.9124 26.9804 0.0 0
M  V30 29 N -5.2843 26.3198 0.0 0
M  V30 30 C -6.6561 27.1328 0.0 0
M  V30 31 C -5.3605 24.9226 0.0 0
M  V30 32 Si 0.2032 -8.1296 0.0 0
M  V30 33 O -0.9145 -9.095 0.0 0
M  V30 34 O 1.4226 -8.7902 0.0 0
M  V30 35 O 1.1686 -7.0118 0.0 0
M  V30 36 C -1.1686 -7.3167 0.0 0
M  V30 37 C -0.254 -10.3145 0.0 0
M  V30 38 C 2.6421 -7.9772 0.0 0
M  V30 39 C 0.0508 -5.894 0.0 0
M  V30 40 C -2.5405 -7.9772 0.0 0
M  V30 41 N -3.9124 -7.1642 0.0 0
M  V30 42 C -5.2843 -7.8248 0.0 0
M  V30 43 C -3.9886 -5.6145 0.0 0
M  V30 44 Si 1.2194 16.0561 0.0 0
M  V30 45 O 0.1016 15.0907 0.0 0
M  V30 46 O 2.4389 15.3956 0.0 0
M  V30 47 O 2.1848 17.1739 0.0 0
M  V30 48 C -0.1524 16.8691 0.0 0
M  V30 49 C 0.7621 13.8712 0.0 0
M  V30 50 C 3.6583 16.2085 0.0 0
M  V30 51 C 1.067 18.2918 0.0 0
M  V30 52 C -1.5243 16.2085 0.0 0
M  V30 53 C -2.8962 17.0215 0.0 0
M  V30 54 N -4.268 16.361 0.0 0
M  V30 55 C -5.6399 17.1739 0.0 0
M  V30 56 C -4.3443 14.9637 0.0 0
M  V30 57 Si 0.0 -15.8529 0.0 0
M  V30 58 O 1.2194 -16.5134 0.0 0
M  V30 59 O 0.9654 -14.735 0.0 0
M  V30 60 O -1.1178 -16.8183 0.0 0
M  V30 61 C -1.3718 -15.0399 0.0 0
M  V30 62 C -2.7437 -15.7004 0.0 0
M  V30 63 N -4.1156 -14.8875 0.0 0
M  V30 64 C -5.4875 -15.548 0.0 0
M  V30 65 C -4.1918 -13.3377 0.0 0
M  V30 66 Si 0.8129 8.7394 0.0 0
M  V30 67 O 2.0324 8.0788 0.0 0
M  V30 68 O 1.7783 9.8572 0.0 0
M  V30 69 O -0.3048 7.774 0.0 0
M  V30 70 C -0.5589 9.5523 0.0 0
M  V30 71 C -1.9308 8.8918 0.0 0
M  V30 72 C -3.3026 9.7048 0.0 0
M  V30 73 N -4.6745 9.0442 0.0 0
M  V30 74 C -6.0464 9.8572 0.0 0
M  V30 75 C -4.7507 7.6469 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 15 1 16 17
M  V30 16 1 16 18
M  V30 17 1 16 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 28 29
M  V30 28 1 29 30
M  V30 29 1 29 31
M  V30 30 1 32 33
M  V30 31 1 32 34
M  V30 32 1 32 35
M  V30 33 1 32 36
M  V30 34 1 33 37
M  V30 35 1 34 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 1 40 41
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 44 45
M  V30 42 1 44 46
M  V30 43 1 44 47
M  V30 44 1 44 48
M  V30 45 1 45 49
M  V30 46 1 46 50
M  V30 47 1 47 51
M  V30 48 1 48 52
M  V30 49 1 52 53
M  V30 50 1 53 54
M  V30 51 1 54 55
M  V30 52 1 54 56
M  V30 53 1 57 58
M  V30 54 1 57 59
M  V30 55 1 57 60
M  V30 56 1 57 61
M  V30 57 1 61 62
M  V30 58 1 62 63
M  V30 59 1 63 64
M  V30 60 1 63 65
M  V30 61 1 66 67
M  V30 62 1 66 68
M  V30 63 1 66 69
M  V30 64 1 66 70
M  V30 65 1 70 71
M  V30 66 1 71 72
M  V30 67 1 72 73
M  V30 68 1 73 74
M  V30 69 1 73 75
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021002.cdx

>  <name>
US20220000749A1-20220106-C00002

>  <Row No>
668

$$$$
US20220000749A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 152 146 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.4598 -0.6122 0.0 0
M  V30 3 O 0.6122 -1.1773 0.0 0
M  V30 4 O -0.8947 1.4598 0.0 0
M  V30 5 C 1.1773 0.8947 0.0 0
M  V30 6 C -2.9197 0.2825 0.0 0
M  V30 7 C 1.9779 -1.036 0.0 0
M  V30 8 C -0.6593 3.061 0.0 0
M  V30 9 C 2.3546 0.2825 0.0 0
M  V30 10 C -4.3796 -0.3296 0.0 0
M  V30 11 C 2.5901 -2.2133 0.0 0
M  V30 12 C 0.7063 3.2023 0.0 0
M  V30 13 C 3.5319 1.1773 0.0 0
M  V30 14 N 4.7093 0.5651 0.0 0
M  V30 15 C 4.568 -0.8005 0.0 0
M  V30 16 C 5.8866 1.4598 0.0 0
M  V30 17 C 5.7453 -1.4127 0.0 0
M  V30 18 C 7.0639 0.8476 0.0 0
M  V30 19 O 5.604 -2.7784 0.0 0
M  V30 20 C 8.2413 1.7424 0.0 0
M  V30 21 Si 9.4186 1.1302 0.0 0
M  V30 22 O 10.3134 2.3546 0.0 0
M  V30 23 O 8.1942 0.1883 0.0 0
M  V30 24 O 10.5959 0.518 0.0 0
M  V30 25 C 9.136 3.5319 0.0 0
M  V30 26 C 8.0529 -1.1773 0.0 0
M  V30 27 C 11.9616 0.6593 0.0 0
M  V30 28 C 10.0308 4.7564 0.0 0
M  V30 29 C 9.3715 -1.4127 0.0 0
M  V30 30 C 12.9035 1.8837 0.0 0
M  V30 31 Si -1.1302 19.5907 0.0 0
M  V30 32 O -2.5901 18.9785 0.0 0
M  V30 33 O -0.518 18.4134 0.0 0
M  V30 34 O -2.025 21.0506 0.0 0
M  V30 35 C 0.047 20.4855 0.0 0
M  V30 36 C -4.05 19.8733 0.0 0
M  V30 37 C 0.8476 18.5547 0.0 0
M  V30 38 C -1.7895 22.6518 0.0 0
M  V30 39 C 1.2244 19.8733 0.0 0
M  V30 40 C -5.5099 19.2611 0.0 0
M  V30 41 C 1.4598 17.3773 0.0 0
M  V30 42 C -0.4238 22.7931 0.0 0
M  V30 43 C 2.4017 20.7681 0.0 0
M  V30 44 N 3.579 20.1558 0.0 0
M  V30 45 C 4.7564 21.0506 0.0 0
M  V30 46 C 3.4378 18.7901 0.0 0
M  V30 47 C 5.9337 20.4384 0.0 0
M  V30 48 C 7.111 21.3332 0.0 0
M  V30 49 Si 8.2884 20.721 0.0 0
M  V30 50 O 9.1831 21.9454 0.0 0
M  V30 51 O 7.0639 19.8262 0.0 0
M  V30 52 O 9.4657 20.1087 0.0 0
M  V30 53 C 8.0058 23.1698 0.0 0
M  V30 54 C 6.9227 18.4605 0.0 0
M  V30 55 C 10.8314 20.25 0.0 0
M  V30 56 C 8.9006 24.3471 0.0 0
M  V30 57 C 8.2413 18.225 0.0 0
M  V30 58 C 11.7733 21.4745 0.0 0
M  V30 59 Si -1.1302 37.6745 0.0 0
M  V30 60 O -2.5901 37.0623 0.0 0
M  V30 61 O -2.025 39.1344 0.0 0
M  V30 62 O -0.518 36.4972 0.0 0
M  V30 63 C 0.047 38.5693 0.0 0
M  V30 64 C -4.05 37.9571 0.0 0
M  V30 65 C -1.7895 40.7356 0.0 0
M  V30 66 C 0.8476 36.6385 0.0 0
M  V30 67 C 1.2244 37.9571 0.0 0
M  V30 68 C -5.5099 37.3449 0.0 0
M  V30 69 C -0.4238 40.8769 0.0 0
M  V30 70 C 1.4598 35.4611 0.0 0
M  V30 71 C 2.4017 38.8518 0.0 0
M  V30 72 N 3.579 38.2396 0.0 0
M  V30 73 C 4.7564 39.1344 0.0 0
M  V30 74 C 5.9337 38.5222 0.0 0
M  V30 75 C 7.111 39.417 0.0 0
M  V30 76 Si 8.2884 38.8048 0.0 0
M  V30 77 O 7.0639 37.8629 0.0 0
M  V30 78 O 9.4657 38.1925 0.0 0
M  V30 79 O 9.1831 39.9821 0.0 0
M  V30 80 C 6.9227 36.4972 0.0 0
M  V30 81 C 10.8314 38.3338 0.0 0
M  V30 82 C 8.0058 41.2065 0.0 0
M  V30 83 C 8.2413 36.2617 0.0 0
M  V30 84 C 11.7733 39.5111 0.0 0
M  V30 85 C 8.9006 42.4309 0.0 0
M  V30 86 Si 7.9116 10.9256 0.0 0
M  V30 87 O 6.6872 9.9837 0.0 0
M  V30 88 O 9.0889 10.3134 0.0 0
M  V30 89 O 8.8535 12.1029 0.0 0
M  V30 90 C 6.4517 11.8203 0.0 0
M  V30 91 C 6.5459 8.618 0.0 0
M  V30 92 C 10.4546 10.4546 0.0 0
M  V30 93 C 7.629 13.3273 0.0 0
M  V30 94 C 4.9918 11.2081 0.0 0
M  V30 95 C 3.5319 12.1029 0.0 0
M  V30 96 N 2.0721 11.4907 0.0 0
M  V30 97 C 1.9308 10.125 0.0 0
M  V30 98 C 0.6122 12.3855 0.0 0
M  V30 99 C 3.2494 9.8895 0.0 0
M  V30 100 C -0.8476 11.7733 0.0 0
M  V30 101 O 3.1081 8.5238 0.0 0
M  V30 102 C -2.3075 12.668 0.0 0
M  V30 103 Si -3.7674 12.0558 0.0 0
M  V30 104 O -5.2273 11.4436 0.0 0
M  V30 105 O -4.6622 13.5157 0.0 0
M  V30 106 O -3.1552 10.8785 0.0 0
M  V30 107 C -6.6872 12.3384 0.0 0
M  V30 108 C -4.4267 15.1169 0.0 0
M  V30 109 C -1.7895 11.0198 0.0 0
M  V30 110 Si 8.2884 28.6326 0.0 0
M  V30 111 O 7.0639 27.7378 0.0 0
M  V30 112 O 9.4657 28.0204 0.0 0
M  V30 113 O 9.2302 29.857 0.0 0
M  V30 114 C 6.8285 29.5274 0.0 0
M  V30 115 C 6.9227 26.3721 0.0 0
M  V30 116 C 10.8314 28.1617 0.0 0
M  V30 117 C 8.0058 31.0815 0.0 0
M  V30 118 C 5.3686 28.9152 0.0 0
M  V30 119 C 3.9087 29.8099 0.0 0
M  V30 120 N 2.4488 29.1977 0.0 0
M  V30 121 C 0.9889 30.0925 0.0 0
M  V30 122 C 2.3075 27.832 0.0 0
M  V30 123 C -0.4709 29.4803 0.0 0
M  V30 124 C -1.9308 30.3751 0.0 0
M  V30 125 Si -3.3907 29.7629 0.0 0
M  V30 126 O -4.8506 29.1506 0.0 0
M  V30 127 O -4.2854 31.2227 0.0 0
M  V30 128 O -2.7784 28.5855 0.0 0
M  V30 129 C -6.3104 30.0454 0.0 0
M  V30 130 C -4.05 32.8239 0.0 0
M  V30 131 C -1.4127 28.7268 0.0 0
M  V30 132 Si 8.6651 48.2234 0.0 0
M  V30 133 O 7.4878 47.3286 0.0 0
M  V30 134 O 9.8424 47.6112 0.0 0
M  V30 135 O 9.607 49.4478 0.0 0
M  V30 136 C 7.2052 49.1182 0.0 0
M  V30 137 C 7.3465 45.9629 0.0 0
M  V30 138 C 11.2081 47.7525 0.0 0
M  V30 139 C 8.3825 50.6722 0.0 0
M  V30 140 C 5.7453 48.506 0.0 0
M  V30 141 C 4.2854 49.4007 0.0 0
M  V30 142 N 2.8255 48.7885 0.0 0
M  V30 143 C 1.3657 49.6833 0.0 0
M  V30 144 C -0.0941 49.0711 0.0 0
M  V30 145 C -1.554 49.9658 0.0 0
M  V30 146 Si -3.0139 49.3536 0.0 0
M  V30 147 O -4.4738 48.7414 0.0 0
M  V30 148 O -3.9087 50.8135 0.0 0
M  V30 149 O -2.4017 48.1763 0.0 0
M  V30 150 C -5.9337 49.6362 0.0 0
M  V30 151 C -3.6732 52.4147 0.0 0
M  V30 152 C -1.036 48.3176 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 47 48
M  V30 47 1 48 49
M  V30 48 1 49 50
M  V30 49 1 49 51
M  V30 50 1 49 52
M  V30 51 1 50 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 59 60
M  V30 58 1 59 61
M  V30 59 1 59 62
M  V30 60 1 59 63
M  V30 61 1 60 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 71 72
M  V30 70 1 72 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 75 76
M  V30 74 1 76 77
M  V30 75 1 76 78
M  V30 76 1 76 79
M  V30 77 1 77 80
M  V30 78 1 78 81
M  V30 79 1 79 82
M  V30 80 1 80 83
M  V30 81 1 81 84
M  V30 82 1 82 85
M  V30 83 1 86 87
M  V30 84 1 86 88
M  V30 85 1 86 89
M  V30 86 1 86 90
M  V30 87 1 87 91
M  V30 88 1 88 92
M  V30 89 1 89 93
M  V30 90 1 90 94
M  V30 91 1 94 95
M  V30 92 1 95 96
M  V30 93 1 96 97
M  V30 94 1 96 98
M  V30 95 1 97 99
M  V30 96 1 98 100
M  V30 97 1 99 101
M  V30 98 1 100 102
M  V30 99 1 102 103
M  V30 100 1 103 104
M  V30 101 1 103 105
M  V30 102 1 103 106
M  V30 103 1 104 107
M  V30 104 1 105 108
M  V30 105 1 106 109
M  V30 106 1 110 111
M  V30 107 1 110 112
M  V30 108 1 110 113
M  V30 109 1 110 114
M  V30 110 1 111 115
M  V30 111 1 112 116
M  V30 112 1 113 117
M  V30 113 1 114 118
M  V30 114 1 118 119
M  V30 115 1 119 120
M  V30 116 1 120 121
M  V30 117 1 120 122
M  V30 118 1 121 123
M  V30 119 1 123 124
M  V30 120 1 124 125
M  V30 121 1 125 126
M  V30 122 1 125 127
M  V30 123 1 125 128
M  V30 124 1 126 129
M  V30 125 1 127 130
M  V30 126 1 128 131
M  V30 127 1 132 133
M  V30 128 1 132 134
M  V30 129 1 132 135
M  V30 130 1 132 136
M  V30 131 1 133 137
M  V30 132 1 134 138
M  V30 133 1 135 139
M  V30 134 1 136 140
M  V30 135 1 140 141
M  V30 136 1 141 142
M  V30 137 1 142 143
M  V30 138 1 143 144
M  V30 139 1 144 145
M  V30 140 1 145 146
M  V30 141 1 146 147
M  V30 142 1 146 148
M  V30 143 1 146 149
M  V30 144 1 147 150
M  V30 145 1 148 151
M  V30 146 1 149 152
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000749A1-20220106-C00003

>  <Row No>
669

$$$$
US20220000749A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 179 173 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.2274 -0.9072 0.0 0
M  V30 3 O 1.1206 -0.587 0.0 0
M  V30 4 O 0.9072 1.2274 0.0 0
M  V30 5 C -1.4408 0.9072 0.0 0
M  V30 6 C -1.3875 -2.2413 0.0 0
M  V30 7 C 2.4548 -0.4269 0.0 0
M  V30 8 C -0.3201 2.4548 0.0 0
M  V30 9 C -2.8817 0.3201 0.0 0
M  V30 10 C -0.1067 -2.4548 0.0 0
M  V30 11 C 3.362 0.8004 0.0 0
M  V30 12 C 0.587 3.6822 0.0 0
M  V30 13 C -4.3226 1.2274 0.0 0
M  V30 14 N -5.7635 0.6403 0.0 0
M  V30 15 C -5.9236 -0.6937 0.0 0
M  V30 16 C -7.2043 1.5476 0.0 0
M  V30 17 C -4.8029 -1.2807 0.0 0
M  V30 18 C -8.6452 0.9605 0.0 0
M  V30 19 C -4.963 -2.6149 0.0 0
M  V30 20 C -10.0861 1.8678 0.0 0
M  V30 21 Si -11.527 1.2807 0.0 0
M  V30 22 O -12.4342 2.7216 0.0 0
M  V30 23 O -10.9399 0.16 0.0 0
M  V30 24 O -12.9678 0.6937 0.0 0
M  V30 25 C -12.2207 4.3226 0.0 0
M  V30 26 C -9.6058 0.3201 0.0 0
M  V30 27 C -14.4087 1.6009 0.0 0
M  V30 28 C -10.8866 4.4827 0.0 0
M  V30 29 C -9.0188 -0.8004 0.0 0
M  V30 30 C -15.8496 1.0139 0.0 0
M  V30 31 Si -2.1346 20.4924 0.0 0
M  V30 32 O -3.362 19.5852 0.0 0
M  V30 33 O -1.0139 19.9054 0.0 0
M  V30 34 O -1.2274 21.7198 0.0 0
M  V30 35 C -3.5755 21.3996 0.0 0
M  V30 36 C -3.5221 18.251 0.0 0
M  V30 37 C 0.3201 20.0655 0.0 0
M  V30 38 C -2.4548 22.9472 0.0 0
M  V30 39 C -5.0163 20.8126 0.0 0
M  V30 40 C -2.2413 18.0376 0.0 0
M  V30 41 C 1.2274 21.2929 0.0 0
M  V30 42 C -1.5476 24.1746 0.0 0
M  V30 43 C -6.4572 21.7198 0.0 0
M  V30 44 N -7.8981 21.1328 0.0 0
M  V30 45 C -8.0582 19.7987 0.0 0
M  V30 46 C -9.339 22.04 0.0 0
M  V30 47 C -6.9375 19.2116 0.0 0
M  V30 48 C -10.7798 21.453 0.0 0
M  V30 49 N -7.0976 17.8775 0.0 0
M  V30 50 C -12.2207 22.3602 0.0 0
M  V30 51 Si -13.6616 21.7732 0.0 0
M  V30 52 O -14.5688 23.2141 0.0 0
M  V30 53 O -13.0746 20.6525 0.0 0
M  V30 54 O -15.1025 21.1862 0.0 0
M  V30 55 C -14.3553 24.815 0.0 0
M  V30 56 C -11.7404 20.8126 0.0 0
M  V30 57 C -16.5433 22.0934 0.0 0
M  V30 58 C -13.0212 24.9751 0.0 0
M  V30 59 C -11.1534 19.6919 0.0 0
M  V30 60 C -17.9842 21.5064 0.0 0
M  V30 61 Si -11.527 42.2656 0.0 0
M  V30 62 O -12.9678 41.6786 0.0 0
M  V30 63 O -12.4342 43.7065 0.0 0
M  V30 64 O -10.9399 41.145 0.0 0
M  V30 65 C -10.4063 43.1729 0.0 0
M  V30 66 C -14.4087 42.5858 0.0 0
M  V30 67 C -12.2207 45.3075 0.0 0
M  V30 68 C -12.1673 40.2377 0.0 0
M  V30 69 C -9.2856 42.5858 0.0 0
M  V30 70 C -15.8496 41.9988 0.0 0
M  V30 71 C -10.8866 45.4676 0.0 0
M  V30 72 C -11.9539 38.957 0.0 0
M  V30 73 C -8.1649 43.4931 0.0 0
M  V30 74 N -7.0442 42.906 0.0 0
M  V30 75 C -7.2043 41.5719 0.0 0
M  V30 76 C -5.9236 43.8132 0.0 0
M  V30 77 C -6.0836 40.9849 0.0 0
M  V30 78 C -4.8029 43.2262 0.0 0
M  V30 79 C -6.2437 39.6507 0.0 0
M  V30 80 C -3.6822 44.1334 0.0 0
M  V30 81 Si -7.6846 39.0637 0.0 0
M  V30 82 Si -2.5615 43.5464 0.0 0
M  V30 83 O -9.1255 39.9709 0.0 0
M  V30 84 O -9.1255 38.4767 0.0 0
M  V30 85 O -6.5639 38.4767 0.0 0
M  V30 86 O -3.7889 42.6392 0.0 0
M  V30 87 O -1.4408 42.9594 0.0 0
M  V30 88 O -1.6543 44.7738 0.0 0
M  V30 89 C -9.2856 41.6253 0.0 0
M  V30 90 C -10.5664 39.3839 0.0 0
M  V30 91 C -5.2832 39.0103 0.0 0
M  V30 92 C -3.949 41.3051 0.0 0
M  V30 93 C -0.1067 43.1195 0.0 0
M  V30 94 C -2.8817 46.0012 0.0 0
M  V30 95 C -10.7265 42.5325 0.0 0
M  V30 96 C -11.7938 38.4767 0.0 0
M  V30 97 C -4.3759 38.1031 0.0 0
M  V30 98 C -2.6149 41.4652 0.0 0
M  V30 99 C 0.1067 44.7205 0.0 0
M  V30 100 C -4.4827 45.7878 0.0 0
M  V30 101 Si -2.5615 11.1 0.0 0
M  V30 102 O -3.7889 10.1928 0.0 0
M  V30 103 O -1.4408 10.513 0.0 0
M  V30 104 O -1.6543 12.3274 0.0 0
M  V30 105 C -4.0024 12.0072 0.0 0
M  V30 106 C -3.949 8.8587 0.0 0
M  V30 107 C -0.1067 10.6731 0.0 0
M  V30 108 C -2.8817 13.5549 0.0 0
M  V30 109 C -5.4433 11.4202 0.0 0
M  V30 110 C -6.8841 12.3274 0.0 0
M  V30 111 N -8.325 11.7404 0.0 0
M  V30 112 C -8.4851 10.4063 0.0 0
M  V30 113 C -9.7659 12.6476 0.0 0
M  V30 114 C -7.2043 10.1928 0.0 0
M  V30 115 C -11.2068 12.0606 0.0 0
M  V30 116 C -7.3644 8.8587 0.0 0
M  V30 117 C -12.6476 12.9678 0.0 0
M  V30 118 Si -14.0885 12.3808 0.0 0
M  V30 119 O -15.5294 11.7938 0.0 0
M  V30 120 O -14.9957 13.8217 0.0 0
M  V30 121 O -13.5015 11.2601 0.0 0
M  V30 122 C -16.9703 12.701 0.0 0
M  V30 123 C -14.7823 15.4227 0.0 0
M  V30 124 C -12.1673 11.4202 0.0 0
M  V30 125 Si -2.5615 29.8848 0.0 0
M  V30 126 O -3.7889 28.9776 0.0 0
M  V30 127 O -1.4408 29.2978 0.0 0
M  V30 128 O -1.6543 31.1122 0.0 0
M  V30 129 C -4.0024 30.792 0.0 0
M  V30 130 C -3.949 27.6434 0.0 0
M  V30 131 C -0.1067 29.4579 0.0 0
M  V30 132 C -2.8817 32.3396 0.0 0
M  V30 133 C -5.4433 30.205 0.0 0
M  V30 134 C -6.8841 31.1122 0.0 0
M  V30 135 N -8.325 30.5252 0.0 0
M  V30 136 C -8.4851 29.191 0.0 0
M  V30 137 C -9.7659 31.4324 0.0 0
M  V30 138 C -7.2043 28.9776 0.0 0
M  V30 139 C -11.2068 30.8454 0.0 0
M  V30 140 N -7.3644 27.6434 0.0 0
M  V30 141 C -12.6476 31.7526 0.0 0
M  V30 142 Si -14.0885 31.1656 0.0 0
M  V30 143 O -15.5294 30.5785 0.0 0
M  V30 144 O -14.9957 32.6064 0.0 0
M  V30 145 O -13.5015 30.0449 0.0 0
M  V30 146 C -16.9703 31.4858 0.0 0
M  V30 147 C -14.7823 34.2074 0.0 0
M  V30 148 C -12.1673 30.205 0.0 0
M  V30 149 Si -2.5615 54.6465 0.0 0
M  V30 150 O -3.7889 53.7393 0.0 0
M  V30 151 O -1.4408 54.0595 0.0 0
M  V30 152 O -1.6543 55.8739 0.0 0
M  V30 153 C -4.0024 55.5537 0.0 0
M  V30 154 C -3.949 52.4051 0.0 0
M  V30 155 C -0.1067 54.2196 0.0 0
M  V30 156 C -2.8817 57.1013 0.0 0
M  V30 157 C -5.4433 54.9667 0.0 0
M  V30 158 C -6.8841 55.8739 0.0 0
M  V30 159 N -8.325 55.2869 0.0 0
M  V30 160 C -9.7659 56.1941 0.0 0
M  V30 161 C -8.4851 53.9527 0.0 0
M  V30 162 C -11.2068 55.6071 0.0 0
M  V30 163 C -7.3644 53.3657 0.0 0
M  V30 164 C -12.6476 56.5143 0.0 0
M  V30 165 C -7.5245 52.0316 0.0 0
M  V30 166 Si -14.0885 55.9273 0.0 0
M  V30 167 Si -8.9654 51.4446 0.0 0
M  V30 168 O -15.5294 55.3403 0.0 0
M  V30 169 O -14.9957 57.3682 0.0 0
M  V30 170 O -13.5015 54.8066 0.0 0
M  V30 171 O -10.4063 52.3518 0.0 0
M  V30 172 O -10.4063 50.8575 0.0 0
M  V30 173 O -7.8447 50.8575 0.0 0
M  V30 174 C -16.9703 56.2475 0.0 0
M  V30 175 C -14.7823 58.9691 0.0 0
M  V30 176 C -12.1673 54.9667 0.0 0
M  V30 177 C -10.5664 54.0061 0.0 0
M  V30 178 C -11.8472 51.7647 0.0 0
M  V30 179 C -6.5639 51.3912 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 46 48
M  V30 47 1 47 49
M  V30 48 1 48 50
M  V30 49 1 50 51
M  V30 50 1 51 52
M  V30 51 1 51 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 56 59
M  V30 58 1 57 60
M  V30 59 1 61 62
M  V30 60 1 61 63
M  V30 61 1 61 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 68 72
M  V30 70 1 69 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 74 76
M  V30 74 1 75 77
M  V30 75 1 76 78
M  V30 76 1 77 79
M  V30 77 1 78 80
M  V30 78 1 79 81
M  V30 79 1 80 82
M  V30 80 1 81 83
M  V30 81 1 81 84
M  V30 82 1 81 85
M  V30 83 1 82 86
M  V30 84 1 82 87
M  V30 85 1 82 88
M  V30 86 1 83 89
M  V30 87 1 84 90
M  V30 88 1 85 91
M  V30 89 1 86 92
M  V30 90 1 87 93
M  V30 91 1 88 94
M  V30 92 1 89 95
M  V30 93 1 90 96
M  V30 94 1 91 97
M  V30 95 1 92 98
M  V30 96 1 93 99
M  V30 97 1 94 100
M  V30 98 1 101 102
M  V30 99 1 101 103
M  V30 100 1 101 104
M  V30 101 1 101 105
M  V30 102 1 102 106
M  V30 103 1 103 107
M  V30 104 1 104 108
M  V30 105 1 105 109
M  V30 106 1 109 110
M  V30 107 1 110 111
M  V30 108 1 111 112
M  V30 109 1 111 113
M  V30 110 1 112 114
M  V30 111 1 113 115
M  V30 112 2 114 116
M  V30 113 1 115 117
M  V30 114 1 117 118
M  V30 115 1 118 119
M  V30 116 1 118 120
M  V30 117 1 118 121
M  V30 118 1 119 122
M  V30 119 1 120 123
M  V30 120 1 121 124
M  V30 121 1 125 126
M  V30 122 1 125 127
M  V30 123 1 125 128
M  V30 124 1 125 129
M  V30 125 1 126 130
M  V30 126 1 127 131
M  V30 127 1 128 132
M  V30 128 1 129 133
M  V30 129 1 133 134
M  V30 130 1 134 135
M  V30 131 1 135 136
M  V30 132 1 135 137
M  V30 133 1 136 138
M  V30 134 1 137 139
M  V30 135 1 138 140
M  V30 136 1 139 141
M  V30 137 1 141 142
M  V30 138 1 142 143
M  V30 139 1 142 144
M  V30 140 1 142 145
M  V30 141 1 143 146
M  V30 142 1 144 147
M  V30 143 1 145 148
M  V30 144 1 149 150
M  V30 145 1 149 151
M  V30 146 1 149 152
M  V30 147 1 149 153
M  V30 148 1 150 154
M  V30 149 1 151 155
M  V30 150 1 152 156
M  V30 151 1 153 157
M  V30 152 1 157 158
M  V30 153 1 158 159
M  V30 154 1 159 160
M  V30 155 1 159 161
M  V30 156 1 160 162
M  V30 157 1 161 163
M  V30 158 1 162 164
M  V30 159 1 163 165
M  V30 160 1 164 166
M  V30 161 1 165 167
M  V30 162 1 166 168
M  V30 163 1 166 169
M  V30 164 1 166 170
M  V30 165 1 167 171
M  V30 166 1 167 172
M  V30 167 1 167 173
M  V30 168 1 168 174
M  V30 169 1 169 175
M  V30 170 1 170 176
M  V30 171 1 171 177
M  V30 172 1 172 178
M  V30 173 1 173 179
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022002.cdx

>  <name>
US20220000749A1-20220106-C00004

>  <Row No>
670

$$$$
US20220000749A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 143 133 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.2091 -0.8637 0.0 0
M  V30 3 O 1.094 -0.5758 0.0 0
M  V30 4 O 0.8637 1.2091 0.0 0
M  V30 5 C -1.4395 0.9212 0.0 0
M  V30 6 C -0.3454 -1.7274 0.0 0
M  V30 7 C 2.188 0.3454 0.0 0
M  V30 8 C -0.3454 2.4183 0.0 0
M  V30 9 C -2.879 0.3454 0.0 0
M  V30 10 C 0.9212 -1.1516 0.0 0
M  V30 11 C 3.282 -0.2303 0.0 0
M  V30 12 C 0.2303 3.8578 0.0 0
M  V30 13 C -4.3185 1.2667 0.0 0
M  V30 14 C -5.758 0.6909 0.0 0
M  V30 15 C -7.1975 1.6122 0.0 0
M  V30 16 C -8.637 1.0364 0.0 0
M  V30 17 C -10.0765 1.9577 0.0 0
M  V30 18 C -11.516 1.3819 0.0 0
M  V30 19 C -12.9556 2.3032 0.0 0
M  V30 20 C -14.3951 1.7274 0.0 0
M  V30 21 C -15.8346 2.6487 0.0 0
M  V30 22 C -17.2741 2.0728 0.0 0
M  V30 23 Si -5.067 17.5044 0.0 0
M  V30 24 O -4.2033 18.7136 0.0 0
M  V30 25 O -3.973 16.9286 0.0 0
M  V30 26 O -6.2762 16.6407 0.0 0
M  V30 27 C -6.5065 18.4257 0.0 0
M  V30 28 C -5.4125 19.9228 0.0 0
M  V30 29 C -2.879 17.8499 0.0 0
M  V30 30 C -5.4125 15.777 0.0 0
M  V30 31 C -7.9461 17.8499 0.0 0
M  V30 32 C -4.5488 21.132 0.0 0
M  V30 33 C -1.7849 17.2741 0.0 0
M  V30 34 C -4.1457 16.3528 0.0 0
M  V30 35 C -9.3856 18.7712 0.0 0
M  V30 36 C -10.8251 18.1954 0.0 0
M  V30 37 C -12.2646 19.1167 0.0 0
M  V30 38 C -13.7041 18.5409 0.0 0
M  V30 39 C -15.1436 19.4621 0.0 0
M  V30 40 C -16.5831 18.8863 0.0 0
M  V30 41 Si -7.3702 32.245 0.0 0
M  V30 42 O -6.5065 33.4542 0.0 0
M  V30 43 O -6.2762 31.6692 0.0 0
M  V30 44 O -8.5794 31.3813 0.0 0
M  V30 45 C -8.8098 33.1663 0.0 0
M  V30 46 C -7.7157 34.6634 0.0 0
M  V30 47 C -5.1822 32.5905 0.0 0
M  V30 48 C -7.7157 30.5176 0.0 0
M  V30 49 C -10.2493 32.5905 0.0 0
M  V30 50 C -6.852 35.8726 0.0 0
M  V30 51 C -4.0882 32.0147 0.0 0
M  V30 52 C -6.449 31.0934 0.0 0
M  V30 53 C -11.6888 33.5118 0.0 0
M  V30 54 C -13.1283 32.936 0.0 0
M  V30 55 C -14.5678 33.8573 0.0 0
M  V30 56 C -16.0073 33.2815 0.0 0
M  V30 57 Si -2.3032 9.6735 0.0 0
M  V30 58 O -1.497 10.8251 0.0 0
M  V30 59 O -3.4548 8.8673 0.0 0
M  V30 60 O -1.2667 9.1552 0.0 0
M  V30 61 C -3.6851 10.5372 0.0 0
M  V30 62 C -2.6487 11.9767 0.0 0
M  V30 63 C -2.6487 8.0612 0.0 0
M  V30 64 C -0.2303 10.019 0.0 0
M  V30 65 C -5.067 10.019 0.0 0
M  V30 66 C -6.449 10.8827 0.0 0
M  V30 67 C -7.8309 10.3644 0.0 0
M  V30 68 C -9.2128 11.2281 0.0 0
M  V30 69 C -10.5948 10.7099 0.0 0
M  V30 70 C -11.9767 11.5736 0.0 0
M  V30 71 C -13.3586 11.0554 0.0 0
M  V30 72 C -14.7405 11.9191 0.0 0
M  V30 73 C -16.1225 11.4009 0.0 0
M  V30 74 C -17.5044 12.2646 0.0 0
M  V30 75 C -18.8863 11.7464 0.0 0
M  V30 76 Si -5.067 25.3354 0.0 0
M  V30 77 O -4.2033 26.5445 0.0 0
M  V30 78 O -6.2762 24.4716 0.0 0
M  V30 79 O -3.973 24.7596 0.0 0
M  V30 80 C -6.5065 26.2566 0.0 0
M  V30 81 C -5.4125 27.7537 0.0 0
M  V30 82 C -5.4125 23.6079 0.0 0
M  V30 83 C -2.879 25.6808 0.0 0
M  V30 84 C -7.9461 25.6808 0.0 0
M  V30 85 C -9.3856 26.6021 0.0 0
M  V30 86 C -10.8251 26.0263 0.0 0
M  V30 87 C -12.2646 26.9476 0.0 0
M  V30 88 C -13.7041 26.3718 0.0 0
M  V30 89 C -15.1436 27.2931 0.0 0
M  V30 90 C -16.5831 26.7173 0.0 0
M  V30 91 Si -7.3702 41.4579 0.0 0
M  V30 92 O -6.5065 42.6671 0.0 0
M  V30 93 O -8.5794 40.5942 0.0 0
M  V30 94 O -6.2762 40.8821 0.0 0
M  V30 95 C -8.8098 42.3792 0.0 0
M  V30 96 C -7.7157 43.8763 0.0 0
M  V30 97 C -7.7157 39.7305 0.0 0
M  V30 98 C -5.1822 41.8034 0.0 0
M  V30 99 C -10.2493 41.8034 0.0 0
M  V30 100 C -11.6888 42.7247 0.0 0
M  V30 101 C -13.1283 42.1489 0.0 0
M  V30 102 C -14.5678 43.0701 0.0 0
M  V30 103 C -16.0073 42.4943 0.0 0
M  V30 104 Si -5.5277 49.7495 0.0 0
M  V30 105 O -6.7369 48.8858 0.0 0
M  V30 106 O -4.4336 49.1737 0.0 0
M  V30 107 O -4.664 50.9587 0.0 0
M  V30 108 C -6.9672 50.6708 0.0 0
M  V30 109 C -5.8732 48.0221 0.0 0
M  V30 110 C -3.3396 50.095 0.0 0
M  V30 111 C -5.8732 52.1679 0.0 0
M  V30 112 C -8.4067 50.095 0.0 0
M  V30 113 C -4.5488 48.1948 0.0 0
M  V30 114 C -2.2456 49.5192 0.0 0
M  V30 115 C -5.0095 53.377 0.0 0
M  V30 116 Si -12.4373 50.2101 0.0 0
M  V30 117 O -11.5736 51.4193 0.0 0
M  V30 118 O -13.6465 49.3464 0.0 0
M  V30 119 O -11.3433 49.6343 0.0 0
M  V30 120 C -13.8768 51.1314 0.0 0
M  V30 121 C -12.7828 52.6285 0.0 0
M  V30 122 C -12.7828 48.4827 0.0 0
M  V30 123 C -10.2493 50.5556 0.0 0
M  V30 124 C -15.3164 50.5556 0.0 0
M  V30 125 Si -5.9883 58.5017 0.0 0
M  V30 126 O -7.1975 57.638 0.0 0
M  V30 127 O -4.8943 57.9259 0.0 0
M  V30 128 O -5.1246 59.7109 0.0 0
M  V30 129 C -7.4278 59.423 0.0 0
M  V30 130 C -6.3338 56.7743 0.0 0
M  V30 131 C -3.8003 58.8472 0.0 0
M  V30 132 C -6.3338 60.9201 0.0 0
M  V30 133 C -5.0095 56.947 0.0 0
M  V30 134 C -2.7062 58.2714 0.0 0
M  V30 135 C -5.4701 62.1293 0.0 0
M  V30 136 Si -12.898 58.9623 0.0 0
M  V30 137 O -12.0343 60.1715 0.0 0
M  V30 138 O -14.1072 58.0986 0.0 0
M  V30 139 O -11.8039 58.3865 0.0 0
M  V30 140 C -14.3375 59.8836 0.0 0
M  V30 141 C -13.2435 61.3807 0.0 0
M  V30 142 C -13.2435 57.2349 0.0 0
M  V30 143 C -10.7099 59.3078 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 23 24
M  V30 23 1 23 25
M  V30 24 1 23 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 25 29
M  V30 28 1 26 30
M  V30 29 1 27 31
M  V30 30 1 28 32
M  V30 31 1 29 33
M  V30 32 1 30 34
M  V30 33 1 31 35
M  V30 34 1 35 36
M  V30 35 1 36 37
M  V30 36 1 37 38
M  V30 37 1 38 39
M  V30 38 1 39 40
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 41 44
M  V30 42 1 41 45
M  V30 43 1 42 46
M  V30 44 1 43 47
M  V30 45 1 44 48
M  V30 46 1 45 49
M  V30 47 1 46 50
M  V30 48 1 47 51
M  V30 49 1 48 52
M  V30 50 1 49 53
M  V30 51 1 53 54
M  V30 52 1 54 55
M  V30 53 1 55 56
M  V30 54 1 57 58
M  V30 55 1 57 59
M  V30 56 1 57 60
M  V30 57 1 57 61
M  V30 58 1 58 62
M  V30 59 1 59 63
M  V30 60 1 60 64
M  V30 61 1 61 65
M  V30 62 1 65 66
M  V30 63 1 66 67
M  V30 64 1 67 68
M  V30 65 1 68 69
M  V30 66 1 69 70
M  V30 67 1 70 71
M  V30 68 1 71 72
M  V30 69 1 72 73
M  V30 70 1 73 74
M  V30 71 1 74 75
M  V30 72 1 76 77
M  V30 73 1 76 78
M  V30 74 1 76 79
M  V30 75 1 76 80
M  V30 76 1 77 81
M  V30 77 1 78 82
M  V30 78 1 79 83
M  V30 79 1 80 84
M  V30 80 1 84 85
M  V30 81 1 85 86
M  V30 82 1 86 87
M  V30 83 1 87 88
M  V30 84 1 88 89
M  V30 85 1 89 90
M  V30 86 1 91 92
M  V30 87 1 91 93
M  V30 88 1 91 94
M  V30 89 1 91 95
M  V30 90 1 92 96
M  V30 91 1 93 97
M  V30 92 1 94 98
M  V30 93 1 95 99
M  V30 94 1 99 100
M  V30 95 1 100 101
M  V30 96 1 101 102
M  V30 97 1 102 103
M  V30 98 1 104 105
M  V30 99 1 104 106
M  V30 100 1 104 107
M  V30 101 1 104 108
M  V30 102 1 105 109
M  V30 103 1 106 110
M  V30 104 1 107 111
M  V30 105 1 108 112
M  V30 106 1 109 113
M  V30 107 1 110 114
M  V30 108 1 111 115
M  V30 109 1 116 117
M  V30 110 1 116 118
M  V30 111 1 116 119
M  V30 112 1 116 120
M  V30 113 1 117 121
M  V30 114 1 118 122
M  V30 115 1 119 123
M  V30 116 1 120 124
M  V30 117 1 125 126
M  V30 118 1 125 127
M  V30 119 1 125 128
M  V30 120 1 125 129
M  V30 121 1 126 130
M  V30 122 1 127 131
M  V30 123 1 128 132
M  V30 124 1 130 133
M  V30 125 1 131 134
M  V30 126 1 132 135
M  V30 127 1 136 137
M  V30 128 1 136 138
M  V30 129 1 136 139
M  V30 130 1 136 140
M  V30 131 1 137 141
M  V30 132 1 138 142
M  V30 133 1 139 143
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000749A1-20220106-C00005

>  <Row No>
671

$$$$
US20220000749A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 46 42 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -0.0866 -1.4724 0.0 0
M  V30 3 O 1.4724 0.0866 0.0 0
M  V30 4 C -0.0866 1.6457 0.0 0
M  V30 5 ? -1.6457 0.0866 0.0 0
M  V30 6 C 1.1837 -2.1654 0.0 0
M  V30 7 ? 2.9449 0.1732 0.0 0
M  V30 8 C 1.0971 -3.6379 0.0 0
M  V30 9 O 2.3675 -4.3308 0.0 0
M  V30 10 ? 2.2809 -5.8033 0.0 0
M  V30 11 Si -0.6929 -14.7827 0.0 0
M  V30 12 O -0.7795 -16.2552 0.0 0
M  V30 13 O 0.7795 -14.696 0.0 0
M  V30 14 C -0.7795 -13.1369 0.0 0
M  V30 15 ? -2.3386 -14.696 0.0 0
M  V30 16 C 0.4908 -16.9481 0.0 0
M  V30 17 ? 2.252 -14.6094 0.0 0
M  V30 18 C 0.4042 -18.4206 0.0 0
M  V30 19 C 1.6746 -19.1135 0.0 0
M  V30 20 O 1.5879 -20.586 0.0 0
M  V30 21 ? 2.8583 -21.279 0.0 0
M  V30 22 Si -0.6929 29.5654 0.0 0
M  V30 23 O 0.7795 29.652 0.0 0
M  V30 24 C -0.7795 28.0929 0.0 0
M  V30 25 C -0.7795 31.2111 0.0 0
M  V30 26 ? -2.3386 29.652 0.0 0
M  V30 27 ? 2.252 29.7386 0.0 0
M  V30 28 C 0.4908 27.3999 0.0 0
M  V30 29 O 0.4042 25.9274 0.0 0
M  V30 30 C 1.6746 25.2345 0.0 0
M  V30 31 C 1.5879 23.762 0.0 0
M  V30 32 O 2.8583 23.0691 0.0 0
M  V30 33 ? 2.7717 21.5966 0.0 0
M  V30 34 Si -0.6929 14.0897 0.0 0
M  V30 35 O 0.7795 14.1763 0.0 0
M  V30 36 C -0.7795 12.6172 0.0 0
M  V30 37 C -0.7795 15.7354 0.0 0
M  V30 38 ? -2.3386 14.1763 0.0 0
M  V30 39 ? 2.252 14.263 0.0 0
M  V30 40 C 0.4908 11.9243 0.0 0
M  V30 41 C 0.4042 10.4518 0.0 0
M  V30 42 O 1.6746 9.7588 0.0 0
M  V30 43 C 1.5879 8.2864 0.0 0
M  V30 44 C 2.8583 7.5934 0.0 0
M  V30 45 O 2.7717 6.1209 0.0 0
M  V30 46 ? 4.0421 5.428 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 11 12
M  V30 11 1 11 13
M  V30 12 1 11 14
M  V30 13 1 11 15
M  V30 14 1 12 16
M  V30 15 1 13 17
M  V30 16 1 16 18
M  V30 17 1 18 19
M  V30 18 1 19 20
M  V30 19 1 20 21
M  V30 20 1 22 23
M  V30 21 1 22 24
M  V30 22 1 22 25
M  V30 23 1 22 26
M  V30 24 1 23 27
M  V30 25 1 24 28
M  V30 26 1 28 29
M  V30 27 1 29 30
M  V30 28 1 30 31
M  V30 29 1 31 32
M  V30 30 1 32 33
M  V30 31 1 34 35
M  V30 32 1 34 36
M  V30 33 1 34 37
M  V30 34 1 34 38
M  V30 35 1 35 39
M  V30 36 1 36 40
M  V30 37 1 40 41
M  V30 38 1 41 42
M  V30 39 1 42 43
M  V30 40 1 43 44
M  V30 41 1 44 45
M  V30 42 1 45 46
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000749A1-20220106-C00006

>  <Row No>
672

$$$$
US20220000749A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0 CFG=2
M  V30 2 O 1.3283 0.0485 0.0 0
M  V30 3 C -0.0485 -1.3283 0.0 0
M  V30 4 C -0.0485 1.4255 0.0 0
M  V30 5 ? -1.4255 0.0485 0.0 0
M  V30 6 ? 2.6567 0.0971 0.0 0
M  V30 7 C -0.0971 -2.6567 0.0 0
M  V30 8 C -0.1457 -3.985 0.0 0
M  V30 9 O 1.7495 -3.9364 0.0 0
M  V30 10 C 3.0779 -3.8878 0.0 0
M  V30 11 C 4.8112 -3.8392 0.0 0
M  V30 12 O 6.8524 -3.7906 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4 CFG=3
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 1)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000749A1-20220106-C00007

>  <Row No>
673

$$$$
US20220000749A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0 CFG=2
M  V30 2 O 1.3283 0.0485 0.0 0
M  V30 3 C -0.0485 -1.3283 0.0 0
M  V30 4 C -0.0485 1.4255 0.0 0
M  V30 5 ? -1.4255 0.0485 0.0 0
M  V30 6 ? 2.6567 0.0971 0.0 0
M  V30 7 C -0.0971 -2.6567 0.0 0
M  V30 8 C -0.1457 -3.985 0.0 0
M  V30 9 O 1.7495 -3.9364 0.0 0
M  V30 10 C 3.0779 -3.8878 0.0 0
M  V30 11 C 4.8112 -3.8392 0.0 0
M  V30 12 O 6.8524 -3.7906 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4 CFG=3
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 1)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000749A1-20220106-C00008

>  <Row No>
674

$$$$
US20220000749A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.3892 0.0555 0.0 0
M  V30 3 C -0.0555 1.5004 0.0 0
M  V30 4 C -1.5004 0.0555 0.0 0
M  V30 5 C -0.0555 -1.3892 0.0 0
M  V30 6 C 2.7785 0.1111 0.0 0
M  V30 7 Si -1.1855 18.9684 0.0 0 CFG=2
M  V30 8 O 0.2037 19.024 0.0 0
M  V30 9 C -1.2411 17.5792 0.0 0
M  V30 10 C -1.2411 20.4689 0.0 0
M  V30 11 ? -2.6859 19.024 0.0 0
M  V30 12 ? 1.593 19.0796 0.0 0
M  V30 13 C -1.2966 16.1899 0.0 0
M  V30 14 C -1.3522 14.8006 0.0 0
M  V30 15 O 0.6668 14.8561 0.0 0
M  V30 16 C 2.0561 14.9117 0.0 0
M  V30 17 C 3.89 14.9673 0.0 0
M  V30 18 O 6.0573 15.0229 0.0 0
M  V30 19 Si -1.1855 9.9288 0.0 0
M  V30 20 O 0.2037 9.9843 0.0 0
M  V30 21 C -1.2411 11.4292 0.0 0
M  V30 22 C -1.2411 8.5395 0.0 0
M  V30 23 ? -2.6859 9.9843 0.0 0
M  V30 24 ? 1.593 10.0399 0.0 0
M  V30 25 Si -1.1855 5.0385 0.0 0
M  V30 26 C -1.2411 6.5389 0.0 0
M  V30 27 C 0.2037 5.094 0.0 0
M  V30 28 C -1.2411 3.6492 0.0 0
M  V30 29 ? -2.6859 5.094 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 7 8
M  V30 7 1 7 9
M  V30 8 1 7 10 CFG=3
M  V30 9 1 7 11
M  V30 10 1 8 12
M  V30 11 1 9 13
M  V30 12 1 13 14
M  V30 13 1 14 15
M  V30 14 1 15 16
M  V30 15 1 16 17
M  V30 16 1 17 18
M  V30 17 1 19 20
M  V30 18 1 19 21
M  V30 19 1 19 22
M  V30 20 1 19 23
M  V30 21 1 20 24
M  V30 22 1 25 26
M  V30 23 1 25 27
M  V30 24 1 25 28
M  V30 25 1 25 29
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 7)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000749A1-20220106-C00009

>  <Row No>
675

$$$$
US20220000749A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0 CFG=2
M  V30 2 O 1.3054 0.0515 0.0 0
M  V30 3 O -1.5459 0.0515 0.0 0
M  V30 4 C -0.0515 -1.3054 0.0 0
M  V30 5 C -0.0515 1.4085 0.0 0
M  V30 6 Si 3.4697 0.103 0.0 0
M  V30 7 Si -3.1777 0.103 0.0 0
M  V30 8 C -0.103 -2.6109 0.0 0
M  V30 9 O 4.9985 0.1545 0.0 0
M  V30 10 C 3.4182 1.5115 0.0 0
M  V30 11 C 3.4182 -1.2023 0.0 0
M  V30 12 C -4.5862 0.1545 0.0 0
M  V30 13 C -3.2292 1.5115 0.0 0
M  V30 14 C -3.2292 -1.2023 0.0 0
M  V30 15 C -0.1545 -3.9163 0.0 0
M  V30 16 Si 6.596 0.2061 0.0 0
M  V30 17 O 1.8551 -3.8648 0.0 0
M  V30 18 C 6.5444 1.6146 0.0 0
M  V30 19 C 6.5444 -1.0993 0.0 0
M  V30 20 C 7.9014 0.2576 0.0 0
M  V30 21 C 3.1605 -3.8133 0.0 0
M  V30 22 C 4.8611 -3.7617 0.0 0
M  V30 23 O 6.8708 -3.7102 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3 CFG=1
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 7 13
M  V30 13 1 7 14
M  V30 14 1 8 15
M  V30 15 1 9 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 1)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000749A1-20220106-C00010

>  <Row No>
676

$$$$
US20220000749A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 2 1 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C 0.7042 -1.3244 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000749A1-20220106-C00011

>  <Row No>
677

$$$$
US20220000749A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C 0.517 -0.8092 0.0 0
M  V30 3 C 0.4495 0.9665 0.0 0
M  V30 4 C -0.0224 -1.6859 0.0 0
M  V30 5 C -0.1573 1.8657 0.0 0
M  V30 6 N 0.4945 -2.4951 0.0 0
M  V30 7 C 0.2922 2.8323 0.0 0
M  V30 8 C -0.4495 3.9112 0.0 0 CFG=2
M  V30 9 C 2.3153 3.9787 0.0 0
M  V30 10 C -3.0571 3.9337 0.0 0
M  V30 11 C 3.5516 4.0461 0.0 0
M  V30 12 ? -4.136 3.9562 0.0 0
M  V30 13 C 6.3839 4.1136 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 7 8
M  V30 8 1 8 9 CFG=1
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 8)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000749A1-20220106-C00012

>  <Row No>
678

$$$$
US20220000749A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000749A1-20220106-C00013

>  <Row No>
679

$$$$
US20220000749A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000749A1-20220106-C00014

>  <Row No>
680

$$$$
US20220000749A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 19 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0 CFG=2
M  V30 2 O 1.3933 0.048 0.0 0
M  V30 3 O -2.05 0.048 0.0 0
M  V30 4 C -0.048 -1.3933 0.0 0
M  V30 5 C -0.048 1.4894 0.0 0
M  V30 6 Si 3.2993 0.096 0.0 0
M  V30 7 Si -3.5395 0.096 0.0 0
M  V30 8 C 1.1371 -2.082 0.0 0
M  V30 9 O 4.6926 0.1441 0.0 0
M  V30 10 C 3.2512 1.5855 0.0 0
M  V30 11 C 3.2512 -1.2972 0.0 0
M  V30 12 A -5.029 0.1441 0.0 0
M  V30 13 C -3.5875 1.5855 0.0 0
M  V30 14 C -3.5875 -1.2972 0.0 0
M  V30 15 C 1.089 -3.4754 0.0 0
M  V30 16 C 6.4064 0.1921 0.0 0
M  V30 17 N -0.1921 -4.1641 0.0 0
M  V30 18 C -0.2402 -5.5575 0.0 0
M  V30 19 C 0.9449 -6.2462 0.0 0
M  V30 20 N 2.1301 -5.4614 0.0 0
M  V30 21 C -4.4844 0.3843 0.0 0
M  V30 22 C -0.7687 0.3843 0.0 0
M  V30 23 C 2.5625 0.3843 0.0 0
M  V30 24 C 5.1251 0.3843 0.0 0
M  V30 25 C 1.5375 0.3843 0.0 0
M  V30 26 C -1.9219 0.3843 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3 CFG=1
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 7 13
M  V30 13 1 7 14
M  V30 14 1 8 15
M  V30 15 1 9 16
M  V30 16 1 15 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 1)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000749A1-20220106-C00015

>  <Row No>
681

$$$$
US20220000749A1-20220106-C00016
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0 CFG=2
M  V30 2 O 1.5584 0.0687 0.0 0
M  V30 3 C -0.0687 -1.2604 0.0 0
M  V30 4 C -0.0687 1.3979 0.0 0
M  V30 5 ? -2.0625 0.0687 0.0 0
M  V30 6 C 4.446 0.1375 0.0 0
M  V30 7 N 0.8021 -2.1313 0.0 0
M  V30 8 C 0.3896 -3.3459 0.0 0
M  V30 9 C 2.0167 -1.7188 0.0 0
M  V30 10 C 1.2604 -4.2168 0.0 0
M  V30 11 C 2.8876 -2.5896 0.0 0
M  V30 12 O 2.4751 -3.8043 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5 CFG=1
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 11 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 1)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00035001.cdx

>  <name>
US20220000749A1-20220106-C00016

>  <Row No>
682

$$$$
US20220000749A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0 CFG=2
M  V30 2 O 1.5584 0.0687 0.0 0
M  V30 3 C -0.0687 -1.2604 0.0 0
M  V30 4 C -0.0687 1.3979 0.0 0
M  V30 5 ? -2.0625 0.0687 0.0 0
M  V30 6 C 4.446 0.1375 0.0 0
M  V30 7 N 0.8021 -2.1313 0.0 0
M  V30 8 C 0.3896 -3.3459 0.0 0
M  V30 9 C 2.0167 -1.7188 0.0 0
M  V30 10 C 1.2604 -4.2168 0.0 0
M  V30 11 C 2.8876 -2.5896 0.0 0
M  V30 12 O 2.4751 -3.8043 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5 CFG=1
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 11 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 1)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000749A1-20220106-C00017

>  <Row No>
683

$$$$
US20220000749A1-20220106-C00018
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 18 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0 CFG=2
M  V30 2 O 1.5187 0.067 0.0 0
M  V30 3 C -0.067 -1.2283 0.0 0
M  V30 4 C -0.067 1.3623 0.0 0
M  V30 5 ? -2.01 0.067 0.0 0
M  V30 6 C 4.3328 0.134 0.0 0
M  V30 7 N 0.7816 -2.077 0.0 0
M  V30 8 C 0.3796 -3.2607 0.0 0
M  V30 9 C 1.9654 -1.675 0.0 0
M  V30 10 C 1.2283 -4.1094 0.0 0
M  V30 11 C 2.8141 -2.5237 0.0 0
M  V30 12 O 2.412 -3.7074 0.0 0
M  V30 13 Si -0.536 9.291 0.0 0
M  V30 14 O 0.9827 9.358 0.0 0
M  V30 15 C -0.603 10.6534 0.0 0
M  V30 16 C -0.603 8.0626 0.0 0
M  V30 17 ? -2.546 9.358 0.0 0
M  V30 18 ? 2.8141 9.425 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5 CFG=1
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 13 14
M  V30 13 1 13 15
M  V30 14 1 13 16
M  V30 15 1 13 17
M  V30 16 1 14 18
M  V30 17 1 11 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 1)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000749A1-20220106-C00018

>  <Row No>
684

$$$$
US20220000749A1-20220106-C00019
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 18 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0 CFG=2
M  V30 2 O 1.5187 0.067 0.0 0
M  V30 3 C -0.067 -1.2283 0.0 0
M  V30 4 C -0.067 1.3623 0.0 0
M  V30 5 ? -2.01 0.067 0.0 0
M  V30 6 C 4.3328 0.134 0.0 0
M  V30 7 N 0.7816 -2.077 0.0 0
M  V30 8 C 0.3796 -3.2607 0.0 0
M  V30 9 C 1.9654 -1.675 0.0 0
M  V30 10 C 1.2283 -4.1094 0.0 0
M  V30 11 C 2.8141 -2.5237 0.0 0
M  V30 12 O 2.412 -3.7074 0.0 0
M  V30 13 Si -0.536 9.291 0.0 0
M  V30 14 O 0.9827 9.358 0.0 0
M  V30 15 C -0.603 10.6534 0.0 0
M  V30 16 C -0.603 8.0626 0.0 0
M  V30 17 ? -2.546 9.358 0.0 0
M  V30 18 ? 2.8141 9.425 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5 CFG=1
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 13 14
M  V30 13 1 13 15
M  V30 14 1 13 16
M  V30 15 1 13 17
M  V30 16 1 14 18
M  V30 17 1 11 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 1)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00038001.cdx

>  <name>
US20220000749A1-20220106-C00019

>  <Row No>
685

$$$$
US20220000749A1-20220106-C00020
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00039001.cdx

>  <name>
US20220000749A1-20220106-C00020

>  <Row No>
686

$$$$
US20220000749A1-20220106-C00021
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00040001.cdx

>  <name>
US20220000749A1-20220106-C00021

>  <Row No>
687

$$$$
US20220000749A1-20220106-C00022
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.0578 0.6347 0.0 0
M  V30 3 O -2.1157 0.1154 0.0 0
M  V30 4 C -1.1155 1.8464 0.0 0 CFG=2
M  V30 5 C -2.1734 -0.9809 0.0 0
M  V30 6 C -2.7119 1.9041 0.0 0
M  V30 7 ? 1.3078 1.9041 0.0 0
M  V30 8 ? -3.9236 1.9618 0.0 0
M  V30 9 C -1.2309 -4.9238 0.0 0
M  V30 10 C -2.8273 -4.8661 0.0 0
M  V30 11 C 0.6731 -4.8661 0.0 0
M  V30 12 ? -4.366 -4.8084 0.0 0
M  V30 13 C -3.0774 -4.9238 0.0 0
M  V30 14 C -0.1538 -4.9238 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7 CFG=3
M  V30 7 1 6 8
M  V30 8 1 9 10
M  V30 9 1 9 11
M  V30 10 1 10 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 4)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00041001.cdx

>  <name>
US20220000749A1-20220106-C00022

>  <Row No>
688

$$$$
US20220000749A1-20220106-C00023
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.0578 0.6347 0.0 0
M  V30 3 O -2.1157 0.1154 0.0 0
M  V30 4 C -1.1155 1.8464 0.0 0 CFG=2
M  V30 5 C -2.1734 -0.9809 0.0 0
M  V30 6 C -2.7119 1.9041 0.0 0
M  V30 7 ? 1.3078 1.9041 0.0 0
M  V30 8 ? -3.9236 1.9618 0.0 0
M  V30 9 C -1.2309 -4.9238 0.0 0
M  V30 10 C -2.8273 -4.8661 0.0 0
M  V30 11 C 0.6731 -4.8661 0.0 0
M  V30 12 ? -4.366 -4.8084 0.0 0
M  V30 13 C -3.0774 -4.9238 0.0 0
M  V30 14 C -0.1538 -4.9238 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7 CFG=3
M  V30 7 1 6 8
M  V30 8 1 9 10
M  V30 9 1 9 11
M  V30 10 1 10 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 4)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00042001.cdx

>  <name>
US20220000749A1-20220106-C00023

>  <Row No>
689

$$$$
US20220000749A1-20220106-C00024
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0 CFG=2
M  V30 2 O 1.2909 0.0516 0.0 0
M  V30 3 C -0.0516 -1.2909 0.0 0
M  V30 4 C -0.0516 1.3942 0.0 0
M  V30 5 ? -1.3942 0.0516 0.0 0
M  V30 6 ? 2.5819 0.1032 0.0 0
M  V30 7 C -0.1032 -2.5819 0.0 0
M  V30 8 C -0.1549 -3.8728 0.0 0
M  V30 9 O 1.945 -3.8212 0.0 0
M  V30 10 C 3.236 -3.7696 0.0 0
M  V30 11 C 4.9228 -3.7179 0.0 0
M  V30 12 O 7.0916 -3.6663 0.0 0
M  V30 13 C 1.2393 -3.4425 0.0 0
M  V30 14 C 5.7834 -3.4425 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4 CFG=3
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 7 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 1)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00056001.cdx

>  <name>
US20220000749A1-20220106-C00024

>  <Row No>
690

$$$$
US20220000749A1-20220106-C00025
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0 CFG=2
M  V30 2 O 1.5584 0.0687 0.0 0
M  V30 3 C -0.0687 -1.2604 0.0 0
M  V30 4 C -0.0687 1.3979 0.0 0
M  V30 5 ? -2.0625 0.0687 0.0 0
M  V30 6 C 4.446 0.1375 0.0 0
M  V30 7 N 0.8021 -2.1313 0.0 0
M  V30 8 C 0.3896 -3.3459 0.0 0
M  V30 9 C 2.0167 -1.7188 0.0 0
M  V30 10 C 1.2604 -4.2168 0.0 0
M  V30 11 C 2.8876 -2.5896 0.0 0
M  V30 12 O 2.4751 -3.8043 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5 CFG=1
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 11 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 1)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00057001.cdx

>  <name>
US20220000749A1-20220106-C00025

>  <Row No>
691

$$$$
US20220000749A1-20220106-C00026
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.0578 0.6347 0.0 0
M  V30 3 O -2.1157 0.1154 0.0 0
M  V30 4 C -1.1155 1.8464 0.0 0 CFG=2
M  V30 5 C -2.1734 -0.9809 0.0 0
M  V30 6 C -2.7119 1.9041 0.0 0
M  V30 7 ? 1.3078 1.9041 0.0 0
M  V30 8 ? -3.9236 1.9618 0.0 0
M  V30 9 C -1.2309 -4.9238 0.0 0
M  V30 10 C -2.8273 -4.8661 0.0 0
M  V30 11 C 0.6731 -4.8661 0.0 0
M  V30 12 ? -4.366 -4.8084 0.0 0
M  V30 13 C -3.0774 -4.9238 0.0 0
M  V30 14 C -0.1538 -4.9238 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7 CFG=3
M  V30 7 1 6 8
M  V30 8 1 9 10
M  V30 9 1 9 11
M  V30 10 1 10 12
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 4)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00058001.cdx

>  <name>
US20220000749A1-20220106-C00026

>  <Row No>
692

$$$$
US20220000750A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 48 44 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 0.7528 1.3175 0.0 0
M  V30 3 O -0.8705 -1.1763 0.0 0
M  V30 4 O 1.2469 -0.6352 0.0 0
M  V30 5 C -1.3646 0.7999 0.0 0
M  V30 6 C -0.1882 2.6115 0.0 0
M  V30 7 C -0.2588 -2.4233 0.0 0
M  V30 8 C 2.4468 0.2352 0.0 0
M  V30 9 C -2.7292 0.1176 0.0 0
M  V30 10 C -1.6939 2.2586 0.0 0
M  V30 11 C 1.0822 -1.8822 0.0 0
M  V30 12 C 3.6938 -0.3999 0.0 0
M  V30 13 N -4.0938 0.9175 0.0 0
M  V30 14 Si 0.7528 24.0923 0.0 0
M  V30 15 O 1.5057 25.4099 0.0 0
M  V30 16 O -0.1176 22.9159 0.0 0
M  V30 17 O 1.9998 23.4571 0.0 0
M  V30 18 C -0.6117 24.8923 0.0 0
M  V30 19 C 0.5646 26.7039 0.0 0
M  V30 20 C 0.494 21.669 0.0 0
M  V30 21 C 3.1997 24.3276 0.0 0
M  V30 22 C -1.9763 24.21 0.0 0
M  V30 23 C -0.9411 26.351 0.0 0
M  V30 24 C 1.8351 22.2101 0.0 0
M  V30 25 C 4.4467 23.6923 0.0 0
M  V30 26 C -3.3409 25.0099 0.0 0
M  V30 27 N -4.7055 24.3276 0.0 0
M  V30 28 Si -0.5646 -8.0935 0.0 0
M  V30 29 O 0.1882 -6.7759 0.0 0
M  V30 30 O -1.4351 -9.2699 0.0 0
M  V30 31 O 0.6823 -8.7287 0.0 0
M  V30 32 C -1.9292 -7.2935 0.0 0
M  V30 33 C -0.7528 -5.4819 0.0 0
M  V30 34 C -0.8234 -10.5168 0.0 0
M  V30 35 C 1.8822 -7.8582 0.0 0
M  V30 36 C -3.2938 -7.9758 0.0 0
M  V30 37 N -4.6584 -7.1759 0.0 0
M  V30 38 Si 0.9411 12.0461 0.0 0
M  V30 39 O 1.6939 13.3637 0.0 0
M  V30 40 O 0.0705 10.8697 0.0 0
M  V30 41 O 2.188 11.4109 0.0 0
M  V30 42 C -0.4234 12.8461 0.0 0
M  V30 43 C 0.7528 14.6577 0.0 0
M  V30 44 C 0.6823 9.6228 0.0 0
M  V30 45 C 3.3879 12.2814 0.0 0
M  V30 46 C -1.7881 12.1638 0.0 0
M  V30 47 C -3.1527 12.9637 0.0 0
M  V30 48 N -4.5173 12.2814 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 14 15
M  V30 14 1 14 16
M  V30 15 1 14 17
M  V30 16 1 14 18
M  V30 17 1 15 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 26 27
M  V30 26 1 28 29
M  V30 27 1 28 30
M  V30 28 1 28 31
M  V30 29 1 28 32
M  V30 30 1 29 33
M  V30 31 1 30 34
M  V30 32 1 31 35
M  V30 33 1 32 36
M  V30 34 1 36 37
M  V30 35 1 38 39
M  V30 36 1 38 40
M  V30 37 1 38 41
M  V30 38 1 38 42
M  V30 39 1 39 43
M  V30 40 1 40 44
M  V30 41 1 41 45
M  V30 42 1 42 46
M  V30 43 1 46 47
M  V30 44 1 47 48
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000750A1-20220106-C00001

>  <Row No>
693

$$$$
US20220000750A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 56 52 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 0.7439 1.325 0.0 0
M  V30 3 O -0.8833 -1.1855 0.0 0
M  V30 4 O 1.2553 -0.6276 0.0 0
M  V30 5 C -1.3715 0.7903 0.0 0
M  V30 6 C -0.1859 2.6036 0.0 0
M  V30 7 C -0.2789 -2.4409 0.0 0
M  V30 8 C 2.4409 0.2324 0.0 0
M  V30 9 C -2.7199 0.0929 0.0 0
M  V30 10 C -1.697 2.2317 0.0 0
M  V30 11 C 1.0693 -1.9062 0.0 0
M  V30 12 C 3.6962 -0.3951 0.0 0
M  V30 13 N -4.0914 0.8833 0.0 0
M  V30 14 C -5.4398 0.1859 0.0 0
M  V30 15 C -4.1844 2.3944 0.0 0
M  V30 16 Si 0.7439 23.8049 0.0 0
M  V30 17 O 1.4878 25.13 0.0 0
M  V30 18 O -0.1394 22.6193 0.0 0
M  V30 19 O 1.9992 23.1772 0.0 0
M  V30 20 C -0.6276 24.5953 0.0 0
M  V30 21 C 0.5579 26.4086 0.0 0
M  V30 22 C 0.4649 21.364 0.0 0
M  V30 23 C 3.1848 24.0374 0.0 0
M  V30 24 C -1.9759 23.8979 0.0 0
M  V30 25 C -0.9298 26.0366 0.0 0
M  V30 26 C 1.8132 21.8986 0.0 0
M  V30 27 C 4.4401 23.4097 0.0 0
M  V30 28 C -3.3475 24.6883 0.0 0
M  V30 29 N -4.6958 23.9909 0.0 0
M  V30 30 C -6.0674 24.7813 0.0 0
M  V30 31 C -4.7423 22.5728 0.0 0
M  V30 32 Si -0.5579 -11.7164 0.0 0
M  V30 33 O 0.1859 -10.3914 0.0 0
M  V30 34 O -1.4413 -12.902 0.0 0
M  V30 35 O 0.6974 -12.3441 0.0 0
M  V30 36 C -1.9295 -10.926 0.0 0
M  V30 37 C -0.7439 -9.1128 0.0 0
M  V30 38 C -0.8368 -14.1574 0.0 0
M  V30 39 C 1.883 -11.484 0.0 0
M  V30 40 C -3.2778 -11.6235 0.0 0
M  V30 41 N -4.6494 -10.8331 0.0 0
M  V30 42 C -5.9977 -11.5305 0.0 0
M  V30 43 C -4.7423 -9.322 0.0 0
M  V30 44 Si 0.7439 11.7164 0.0 0
M  V30 45 O 1.4878 13.0415 0.0 0
M  V30 46 O -0.1394 10.5308 0.0 0
M  V30 47 O 1.9992 11.0888 0.0 0
M  V30 48 C -0.6276 12.5068 0.0 0
M  V30 49 C 0.5579 14.3201 0.0 0
M  V30 50 C 0.4649 9.2755 0.0 0
M  V30 51 C 3.1848 11.9489 0.0 0
M  V30 52 C -1.9759 11.8094 0.0 0
M  V30 53 C -3.3475 12.5998 0.0 0
M  V30 54 N -4.6958 11.9024 0.0 0
M  V30 55 C -6.0674 12.6928 0.0 0
M  V30 56 C -4.7423 10.4844 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 15 1 16 17
M  V30 16 1 16 18
M  V30 17 1 16 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 28 29
M  V30 28 1 29 30
M  V30 29 1 29 31
M  V30 30 1 32 33
M  V30 31 1 32 34
M  V30 32 1 32 35
M  V30 33 1 32 36
M  V30 34 1 33 37
M  V30 35 1 34 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 1 40 41
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 44 45
M  V30 42 1 44 46
M  V30 43 1 44 47
M  V30 44 1 44 48
M  V30 45 1 45 49
M  V30 46 1 46 50
M  V30 47 1 47 51
M  V30 48 1 48 52
M  V30 49 1 52 53
M  V30 50 1 53 54
M  V30 51 1 54 55
M  V30 52 1 54 56
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021002.cdx

>  <name>
US20220000750A1-20220106-C00002

>  <Row No>
694

$$$$
US20220000750A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 70 67 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.2521 -0.8463 0.0 0
M  V30 3 O -0.9622 1.2173 0.0 0
M  V30 4 O 0.8347 -1.1941 0.0 0
M  V30 5 C 1.2521 0.8115 0.0 0
M  V30 6 C -2.6549 -0.2086 0.0 0
M  V30 7 C -0.4869 2.6549 0.0 0
M  V30 8 C 2.2955 -1.1593 0.0 0
M  V30 9 C 2.5273 0.1275 0.0 0
M  V30 10 C -3.9997 -0.8811 0.0 0
M  V30 11 C 0.9738 2.6781 0.0 0
M  V30 12 C 2.9911 -2.423 0.0 0
M  V30 13 C 3.7794 0.939 0.0 0
M  V30 14 N 5.0547 0.255 0.0 0
M  V30 15 C 6.3068 1.0666 0.0 0
M  V30 16 C 7.5821 0.3825 0.0 0
M  V30 17 C 8.8342 1.1941 0.0 0
M  V30 18 Si 10.1095 0.5101 0.0 0
M  V30 19 O 10.8979 1.8085 0.0 0
M  V30 20 O 9.2516 -0.7187 0.0 0
M  V30 21 O 11.3964 -0.1391 0.0 0
M  V30 22 C 10.1907 3.1766 0.0 0
M  V30 23 C 9.2052 -2.1795 0.0 0
M  V30 24 C 12.8572 -0.1043 0.0 0
M  V30 25 C 11.0254 4.4403 0.0 0
M  V30 26 C 10.5617 -2.6896 0.0 0
M  V30 27 C 13.5992 1.2173 0.0 0
M  V30 28 Si 8.811 -11.3152 0.0 0
M  V30 29 O 9.5994 -10.0168 0.0 0
M  V30 30 O 7.9531 -12.5441 0.0 0
M  V30 31 O 10.0979 -11.9645 0.0 0
M  V30 32 C 7.4662 -10.5501 0.0 0
M  V30 33 C 8.8922 -8.6487 0.0 0
M  V30 34 C 7.9067 -14.0049 0.0 0
M  V30 35 C 11.5587 -11.9297 0.0 0
M  V30 36 C 6.1445 -11.292 0.0 0
M  V30 37 C 4.7997 -10.5269 0.0 0
M  V30 38 N 3.478 -11.2689 0.0 0
M  V30 39 C 2.1332 -10.5037 0.0 0
M  V30 40 C 3.4664 -12.7296 0.0 0
M  V30 41 C 0.8115 -11.2457 0.0 0
M  V30 42 C -0.5333 -10.4805 0.0 0
M  V30 43 Si -1.8549 -11.2225 0.0 0
M  V30 44 O -2.8172 -10.0052 0.0 0
M  V30 45 O -1.0202 -12.4166 0.0 0
M  V30 46 O -3.107 -12.0688 0.0 0
M  V30 47 C -2.3418 -8.5676 0.0 0
M  V30 48 C 0.4405 -12.3818 0.0 0
M  V30 49 C -4.5098 -11.4312 0.0 0
M  V30 50 Si 8.811 10.9442 0.0 0
M  V30 51 O 9.5994 12.2427 0.0 0
M  V30 52 O 7.9531 9.7153 0.0 0
M  V30 53 O 10.0979 10.295 0.0 0
M  V30 54 C 7.4662 11.721 0.0 0
M  V30 55 C 8.8922 13.6107 0.0 0
M  V30 56 C 7.9067 8.2545 0.0 0
M  V30 57 C 11.5587 10.3298 0.0 0
M  V30 58 C 6.1445 10.979 0.0 0
M  V30 59 C 4.7997 11.7558 0.0 0
M  V30 60 N 3.478 11.0138 0.0 0
M  V30 61 C 2.1332 11.7906 0.0 0
M  V30 62 C 0.8115 11.0486 0.0 0
M  V30 63 C -0.5333 11.8138 0.0 0
M  V30 64 Si -1.8549 11.0718 0.0 0
M  V30 65 O -2.8172 12.2891 0.0 0
M  V30 66 O -1.0202 9.8776 0.0 0
M  V30 67 O -3.107 10.2254 0.0 0
M  V30 68 C -2.3418 13.7267 0.0 0
M  V30 69 C 0.4405 9.9124 0.0 0
M  V30 70 C -4.5098 10.8631 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 28 29
M  V30 28 1 28 30
M  V30 29 1 28 31
M  V30 30 1 28 32
M  V30 31 1 29 33
M  V30 32 1 30 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 36 37
M  V30 36 1 37 38
M  V30 37 1 38 39
M  V30 38 1 38 40
M  V30 39 1 39 41
M  V30 40 1 41 42
M  V30 41 1 42 43
M  V30 42 1 43 44
M  V30 43 1 43 45
M  V30 44 1 43 46
M  V30 45 1 44 47
M  V30 46 1 45 48
M  V30 47 1 46 49
M  V30 48 1 50 51
M  V30 49 1 50 52
M  V30 50 1 50 53
M  V30 51 1 50 54
M  V30 52 1 51 55
M  V30 53 1 52 56
M  V30 54 1 53 57
M  V30 55 1 54 58
M  V30 56 1 58 59
M  V30 57 1 59 60
M  V30 58 1 60 61
M  V30 59 1 61 62
M  V30 60 1 62 63
M  V30 61 1 63 64
M  V30 62 1 64 65
M  V30 63 1 64 66
M  V30 64 1 64 67
M  V30 65 1 65 68
M  V30 66 1 66 69
M  V30 67 1 67 70
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000750A1-20220106-C00003

>  <Row No>
695

$$$$
US20220000750A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 82 79 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.2152 -0.7386 0.0 0
M  V30 3 O -0.9293 1.1676 0.0 0
M  V30 4 O 0.7386 -1.0722 0.0 0
M  V30 5 C 1.1199 0.7863 0.0 0
M  V30 6 C -2.5496 -0.0953 0.0 0
M  V30 7 C -0.5242 2.5496 0.0 0
M  V30 8 C 2.073 -1.0008 0.0 0
M  V30 9 C 2.2637 0.1668 0.0 0
M  V30 10 C -3.8364 -0.691 0.0 0
M  V30 11 C 0.8101 2.6211 0.0 0
M  V30 12 C 2.6926 -2.1445 0.0 0
M  V30 13 C 3.3836 0.9531 0.0 0
M  V30 14 N 4.5274 0.3336 0.0 0
M  V30 15 C 4.4797 -1.0008 0.0 0
M  V30 16 C 5.6473 1.1199 0.0 0
M  V30 17 C 5.7665 -1.239 0.0 0
M  V30 18 C 6.7911 0.5004 0.0 0
M  V30 19 O 5.7188 -2.5734 0.0 0
M  V30 20 C 7.911 1.2867 0.0 0
M  V30 21 Si 9.0548 0.6672 0.0 0
M  V30 22 O 8.2208 -0.4289 0.0 0
M  V30 23 O 10.2224 0.0953 0.0 0
M  V30 24 O 9.7459 1.9062 0.0 0
M  V30 25 C 8.1255 -1.7633 0.0 0
M  V30 26 C 11.5568 0.1668 0.0 0
M  V30 27 C 9.031 3.2168 0.0 0
M  V30 28 C 9.3408 -2.216 0.0 0
M  V30 29 C 12.2002 1.4297 0.0 0
M  V30 30 C 9.8888 4.3368 0.0 0
M  V30 31 Si 0.0 24.4004 0.0 0
M  V30 32 O -1.382 23.5426 0.0 0
M  V30 33 O -1.0484 25.7349 0.0 0
M  V30 34 O 0.8578 23.1614 0.0 0
M  V30 35 C 1.3105 25.2821 0.0 0
M  V30 36 C -2.907 24.2813 0.0 0
M  V30 37 C -0.5718 27.2837 0.0 0
M  V30 38 C 2.3352 23.2328 0.0 0
M  V30 39 C 2.6449 24.5672 0.0 0
M  V30 40 C -4.3844 23.5903 0.0 0
M  V30 41 C 0.9054 27.3552 0.0 0
M  V30 42 C 3.05 21.9223 0.0 0
M  V30 43 C 3.9555 25.4489 0.0 0
M  V30 44 N 5.2899 24.734 0.0 0
M  V30 45 C 6.6005 25.6157 0.0 0
M  V30 46 C 5.2422 23.2567 0.0 0
M  V30 47 C 7.9349 24.9009 0.0 0
M  V30 48 C 9.2455 25.7825 0.0 0
M  V30 49 Si 10.5799 25.0677 0.0 0
M  V30 50 O 9.6505 23.8047 0.0 0
M  V30 51 O 11.3662 26.4735 0.0 0
M  V30 52 O 11.9143 24.4004 0.0 0
M  V30 53 C 9.5552 22.3035 0.0 0
M  V30 54 C 10.556 27.9747 0.0 0
M  V30 55 C 13.3916 24.4719 0.0 0
M  V30 56 C 10.9611 21.7793 0.0 0
M  V30 57 C 11.676 29.1185 0.0 0
M  V30 58 C 14.5592 25.5681 0.0 0
M  V30 59 Si 9.5314 14.2971 0.0 0
M  V30 60 O 8.6021 13.0342 0.0 0
M  V30 61 O 10.8658 13.6299 0.0 0
M  V30 62 O 10.3177 15.703 0.0 0
M  V30 63 C 8.054 15.1549 0.0 0
M  V30 64 C 8.5068 11.533 0.0 0
M  V30 65 C 12.3432 13.7014 0.0 0
M  V30 66 C 9.1978 16.9659 0.0 0
M  V30 67 C 6.6005 14.4163 0.0 0
M  V30 68 C 5.1231 15.2741 0.0 0
M  V30 69 N 3.6696 14.5354 0.0 0
M  V30 70 C 3.6219 13.058 0.0 0
M  V30 71 C 2.1922 15.3932 0.0 0
M  V30 72 C 5.0993 12.7721 0.0 0
M  V30 73 C 0.7386 14.6545 0.0 0
M  V30 74 O 5.0278 11.2947 0.0 0
M  V30 75 C -0.7386 15.5124 0.0 0
M  V30 76 Si -2.1922 14.7737 0.0 0
M  V30 77 O -3.2406 16.1081 0.0 0
M  V30 78 O -1.3344 13.5346 0.0 0
M  V30 79 O -3.5742 13.9159 0.0 0
M  V30 80 C -2.7641 17.657 0.0 0
M  V30 81 C 0.1429 13.6061 0.0 0
M  V30 82 C -5.0993 14.6545 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 47 48
M  V30 47 1 48 49
M  V30 48 1 49 50
M  V30 49 1 49 51
M  V30 50 1 49 52
M  V30 51 1 50 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 59 60
M  V30 58 1 59 61
M  V30 59 1 59 62
M  V30 60 1 59 63
M  V30 61 1 60 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 67 68
M  V30 66 1 68 69
M  V30 67 1 69 70
M  V30 68 1 69 71
M  V30 69 1 70 72
M  V30 70 1 71 73
M  V30 71 1 72 74
M  V30 72 1 73 75
M  V30 73 1 75 76
M  V30 74 1 76 77
M  V30 75 1 76 78
M  V30 76 1 76 79
M  V30 77 1 77 80
M  V30 78 1 78 81
M  V30 79 1 79 82
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022002.cdx

>  <name>
US20220000750A1-20220106-C00004

>  <Row No>
696

$$$$
US20220000750A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 94 91 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -0.9475 1.2164 0.0 0
M  V30 3 O 0.8194 -1.178 0.0 0
M  V30 4 O -1.2548 -0.8322 0.0 0
M  V30 5 C 1.242 0.8194 0.0 0
M  V30 6 C -0.4609 2.6633 0.0 0
M  V30 7 C -0.1536 -2.3048 0.0 0
M  V30 8 C -2.6633 -0.1664 0.0 0
M  V30 9 C 2.5096 0.1152 0.0 0
M  V30 10 C 0.9987 2.6889 0.0 0
M  V30 11 C 0.2817 -3.6877 0.0 0
M  V30 12 C -4.123 -0.6146 0.0 0
M  V30 13 C 3.7517 0.9347 0.0 0
M  V30 14 N 5.0193 0.2304 0.0 0
M  V30 15 C 5.0065 -1.2292 0.0 0
M  V30 16 C 6.2614 1.0499 0.0 0
M  V30 17 C 6.2742 -1.9462 0.0 0
M  V30 18 C 7.529 0.3457 0.0 0
M  V30 19 C 6.2358 -3.406 0.0 0
M  V30 20 C 8.7711 1.1652 0.0 0
M  V30 21 Si 4.8913 -4.1358 0.0 0
M  V30 22 Si 10.0387 0.4609 0.0 0
M  V30 23 O 6.1077 -4.9297 0.0 0
M  V30 24 O 3.598 -4.9169 0.0 0
M  V30 25 O 3.5468 -3.3291 0.0 0
M  V30 26 O 10.8326 1.7542 0.0 0
M  V30 27 O 11.3192 -0.2176 0.0 0
M  V30 28 O 9.2064 -0.7554 0.0 0
M  V30 29 C 7.5162 -4.4815 0.0 0
M  V30 30 C 2.2279 -4.187 0.0 0
M  V30 31 C 3.5084 -1.7926 0.0 0
M  V30 32 C 9.8082 2.9194 0.0 0
M  V30 33 C 12.7789 -0.1792 0.0 0
M  V30 34 C 9.1552 -2.2151 0.0 0
M  V30 35 C 8.579 -5.4547 0.0 0
M  V30 36 C 1.178 -5.2498 0.0 0
M  V30 37 C 2.2407 -0.9091 0.0 0
M  V30 38 C 8.3229 2.5609 0.0 0
M  V30 39 C 13.2271 1.2804 0.0 0
M  V30 40 Si 8.6046 -11.7801 0.0 0
M  V30 41 O 9.3857 -10.4869 0.0 0
M  V30 42 O 7.7723 -12.9966 0.0 0
M  V30 43 O 9.8851 -12.4588 0.0 0
M  V30 44 C 7.2601 -10.9991 0.0 0
M  V30 45 C 8.6558 -9.1168 0.0 0
M  V30 46 C 7.7211 -14.4563 0.0 0
M  V30 47 C 11.3448 -12.4204 0.0 0
M  V30 48 C 5.9413 -11.7417 0.0 0
M  V30 49 C 4.5968 -10.9607 0.0 0
M  V30 50 N 3.2779 -11.7033 0.0 0
M  V30 51 C 3.2651 -13.163 0.0 0
M  V30 52 C 1.9334 -10.9222 0.0 0
M  V30 53 C 4.6864 -13.4703 0.0 0
M  V30 54 C 0.6146 -11.6649 0.0 0
M  V30 55 O 4.6736 -14.9301 0.0 0
M  V30 56 C -0.7298 -10.8838 0.0 0
M  V30 57 Si -2.0487 -11.6265 0.0 0
M  V30 58 O -2.9962 -10.4101 0.0 0
M  V30 59 O -1.2292 -12.8045 0.0 0
M  V30 60 O -3.3035 -12.4588 0.0 0
M  V30 61 C -2.5096 -8.9631 0.0 0
M  V30 62 C 0.2304 -12.7661 0.0 0
M  V30 63 C -4.712 -11.7929 0.0 0
M  V30 64 Si 8.6046 13.1118 0.0 0
M  V30 65 O 7.7723 11.8954 0.0 0
M  V30 66 O 9.8851 12.4332 0.0 0
M  V30 67 O 9.3857 14.4051 0.0 0
M  V30 68 C 7.2601 13.8929 0.0 0
M  V30 69 C 7.7211 10.4357 0.0 0
M  V30 70 C 11.3448 12.4716 0.0 0
M  V30 71 C 8.3613 15.5703 0.0 0
M  V30 72 C 5.9413 13.1502 0.0 0
M  V30 73 C 4.5968 13.9313 0.0 0
M  V30 74 N 3.2779 13.1886 0.0 0
M  V30 75 C 1.9334 13.9697 0.0 0
M  V30 76 C 3.2651 11.7289 0.0 0
M  V30 77 C 0.6146 13.2271 0.0 0
M  V30 78 C 4.5328 11.0119 0.0 0
M  V30 79 C -0.7298 14.0081 0.0 0
M  V30 80 C 4.4943 9.5521 0.0 0
M  V30 81 Si -2.0487 13.2655 0.0 0
M  V30 82 Si 3.1499 8.8223 0.0 0
M  V30 83 O -2.9962 14.4819 0.0 0
M  V30 84 O -1.2292 12.0875 0.0 0
M  V30 85 O -3.3035 12.4332 0.0 0
M  V30 86 O 1.8054 9.629 0.0 0
M  V30 87 O 1.8566 8.0284 0.0 0
M  V30 88 O 4.3663 8.0284 0.0 0
M  V30 89 C -2.5096 15.9288 0.0 0
M  V30 90 C 0.2304 12.1259 0.0 0
M  V30 91 C -4.712 13.099 0.0 0
M  V30 92 C 1.767 11.1655 0.0 0
M  V30 93 C 0.4865 8.7583 0.0 0
M  V30 94 C 5.7748 8.4766 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 22 27
M  V30 27 1 22 28
M  V30 28 1 23 29
M  V30 29 1 24 30
M  V30 30 1 25 31
M  V30 31 1 26 32
M  V30 32 1 27 33
M  V30 33 1 28 34
M  V30 34 1 29 35
M  V30 35 1 30 36
M  V30 36 1 31 37
M  V30 37 1 32 38
M  V30 38 1 33 39
M  V30 39 1 40 41
M  V30 40 1 40 42
M  V30 41 1 40 43
M  V30 42 1 40 44
M  V30 43 1 41 45
M  V30 44 1 42 46
M  V30 45 1 43 47
M  V30 46 1 44 48
M  V30 47 1 48 49
M  V30 48 1 49 50
M  V30 49 1 50 51
M  V30 50 1 50 52
M  V30 51 1 51 53
M  V30 52 1 52 54
M  V30 53 1 53 55
M  V30 54 1 54 56
M  V30 55 1 56 57
M  V30 56 1 57 58
M  V30 57 1 57 59
M  V30 58 1 57 60
M  V30 59 1 58 61
M  V30 60 1 59 62
M  V30 61 1 60 63
M  V30 62 1 64 65
M  V30 63 1 64 66
M  V30 64 1 64 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 68 72
M  V30 70 1 72 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 74 76
M  V30 74 1 75 77
M  V30 75 1 76 78
M  V30 76 1 77 79
M  V30 77 1 78 80
M  V30 78 1 79 81
M  V30 79 1 80 82
M  V30 80 1 81 83
M  V30 81 1 81 84
M  V30 82 1 81 85
M  V30 83 1 82 86
M  V30 84 1 82 87
M  V30 85 1 82 88
M  V30 86 1 83 89
M  V30 87 1 84 90
M  V30 88 1 85 91
M  V30 89 1 86 92
M  V30 90 1 87 93
M  V30 91 1 88 94
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022003.cdx

>  <name>
US20220000750A1-20220106-C00005

>  <Row No>
697

$$$$
US20220000750A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 81 78 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -0.8751 -1.2062 0.0 0
M  V30 3 O 0.7568 1.3245 0.0 0
M  V30 4 O 1.2535 -0.6386 0.0 0
M  V30 5 C -1.3718 0.8041 0.0 0
M  V30 6 C -0.9697 -2.649 0.0 0
M  V30 7 C 0.0 2.7436 0.0 0
M  V30 8 C 2.6963 -0.5676 0.0 0
M  V30 9 C -2.7436 0.0946 0.0 0
M  V30 10 C 0.3311 -3.1693 0.0 0
M  V30 11 C 1.1116 3.7369 0.0 0
M  V30 12 C 3.5004 0.7095 0.0 0
M  V30 13 C -4.1154 0.8987 0.0 0
M  V30 14 N -5.4872 0.1892 0.0 0
M  V30 15 C -5.5345 -1.2535 0.0 0
M  V30 16 C -6.8826 0.9933 0.0 0
M  V30 17 C -4.3282 -1.9631 0.0 0
M  V30 18 C -8.2545 0.2838 0.0 0
M  V30 19 C -4.3992 -3.4058 0.0 0
M  V30 20 C -9.6499 1.0879 0.0 0
M  V30 21 Si -11.0217 0.3784 0.0 0
M  V30 22 O -12.3226 -0.4257 0.0 0
M  V30 23 O -10.2176 -0.7805 0.0 0
M  V30 24 O -12.0151 1.6319 0.0 0
M  V30 25 C -13.7653 0.2601 0.0 0
M  V30 26 C -8.7748 -0.7095 0.0 0
M  V30 27 C -11.5657 3.122 0.0 0
M  V30 28 C -15.1845 -0.3311 0.0 0
M  V30 29 C -8.1598 -1.9631 0.0 0
M  V30 30 Si -10.9744 24.2195 0.0 0
M  V30 31 O -12.2753 23.4153 0.0 0
M  V30 32 O -10.1703 23.0605 0.0 0
M  V30 33 O -11.9678 25.473 0.0 0
M  V30 34 C -9.7445 25.0709 0.0 0
M  V30 35 C -13.718 24.1012 0.0 0
M  V30 36 C -8.7275 23.1315 0.0 0
M  V30 37 C -11.5184 26.9631 0.0 0
M  V30 38 C -8.5146 24.4087 0.0 0
M  V30 39 C -15.1371 23.5099 0.0 0
M  V30 40 C -7.8287 22.0435 0.0 0
M  V30 41 C -10.0756 27.0577 0.0 0
M  V30 42 C -7.2847 25.2602 0.0 0
M  V30 43 N -6.0312 24.5979 0.0 0
M  V30 44 C -4.8013 25.4494 0.0 0
M  V30 45 C -6.0785 23.1551 0.0 0
M  V30 46 C -3.5477 24.7871 0.0 0
M  V30 47 C -4.8486 22.4929 0.0 0
M  V30 48 C -2.3178 25.6386 0.0 0
M  V30 49 C -4.9195 21.0501 0.0 0
M  V30 50 Si -1.0643 24.9763 0.0 0
M  V30 51 O -1.9394 23.7701 0.0 0
M  V30 52 O 0.1892 24.3377 0.0 0
M  V30 53 O -0.3074 26.3008 0.0 0
M  V30 54 C -2.034 22.3273 0.0 0
M  V30 55 C 1.6319 24.4087 0.0 0
M  V30 56 C -1.3718 27.5071 0.0 0
M  V30 57 C -0.6622 21.9489 0.0 0
M  V30 58 Si -1.8921 12.8666 0.0 0
M  V30 59 O -2.7672 11.6603 0.0 0
M  V30 60 O -0.6386 12.228 0.0 0
M  V30 61 O -1.1352 14.1911 0.0 0
M  V30 62 C -3.2876 13.6707 0.0 0
M  V30 63 C -2.8618 10.2176 0.0 0
M  V30 64 C 0.8041 12.2989 0.0 0
M  V30 65 C -2.1996 15.3973 0.0 0
M  V30 66 C -4.6594 12.9612 0.0 0
M  V30 67 C -6.0548 13.7653 0.0 0
M  V30 68 N -7.4266 13.0558 0.0 0
M  V30 69 C -7.4739 11.613 0.0 0
M  V30 70 C -8.8221 13.8599 0.0 0
M  V30 71 C -6.244 10.9508 0.0 0
M  V30 72 C -10.1939 13.1504 0.0 0
M  V30 73 C -6.315 9.508 0.0 0
M  V30 74 C -11.5657 13.9546 0.0 0
M  V30 75 Si -12.9375 13.245 0.0 0
M  V30 76 O -13.9309 14.4985 0.0 0
M  V30 77 O -14.2384 12.4408 0.0 0
M  V30 78 O -12.1334 12.0861 0.0 0
M  V30 79 C -13.4815 15.9886 0.0 0
M  V30 80 C -15.6811 13.1267 0.0 0
M  V30 81 C -10.6906 12.157 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 30 31
M  V30 30 1 30 32
M  V30 31 1 30 33
M  V30 32 1 30 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 42 43
M  V30 42 1 43 44
M  V30 43 1 43 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 46 48
M  V30 47 1 47 49
M  V30 48 1 48 50
M  V30 49 1 50 51
M  V30 50 1 50 52
M  V30 51 1 50 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 58 59
M  V30 57 1 58 60
M  V30 58 1 58 61
M  V30 59 1 58 62
M  V30 60 1 59 63
M  V30 61 1 60 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 66 67
M  V30 65 1 67 68
M  V30 66 1 68 69
M  V30 67 1 68 70
M  V30 68 1 69 71
M  V30 69 1 70 72
M  V30 70 2 71 73
M  V30 71 1 72 74
M  V30 72 1 74 75
M  V30 73 1 75 76
M  V30 74 1 75 77
M  V30 75 1 75 78
M  V30 76 1 76 79
M  V30 77 1 77 80
M  V30 78 1 78 81
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022004.cdx

>  <name>
US20220000750A1-20220106-C00006

>  <Row No>
698

$$$$
US20220000750A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2254 -0.7104 0.0 0
M  V30 3 O 1.03 1.1366 0.0 0
M  V30 4 O -1.1188 -1.03 0.0 0
M  V30 5 C -1.332 0.8347 0.0 0
M  V30 6 C 2.4509 0.1065 0.0 0
M  V30 7 C -0.1065 2.2733 0.0 0
M  V30 8 C -0.3907 -2.2555 0.0 0
M  V30 9 C -2.6818 0.142 0.0 0
M  V30 10 Si -1.7049 8.3828 0.0 0
M  V30 11 O -0.6748 9.5195 0.0 0
M  V30 12 O -2.8238 7.3527 0.0 0
M  V30 13 O -0.4795 7.6724 0.0 0
M  V30 14 C -3.037 9.2176 0.0 0
M  V30 15 C -1.776 10.6561 0.0 0
M  V30 16 C -2.1134 6.1273 0.0 0
M  V30 17 C 0.7459 8.5071 0.0 0
M  V30 18 C -0.7281 11.7573 0.0 0
M  V30 19 C -0.6748 6.1805 0.0 0
M  V30 20 C 1.9891 7.8145 0.0 0
M  V30 21 Si -1.7049 18.1865 0.0 0
M  V30 22 O -0.4617 17.4939 0.0 0
M  V30 23 O -0.6926 19.3232 0.0 0
M  V30 24 O -2.8416 17.1564 0.0 0
M  V30 25 C -3.0547 18.9857 0.0 0
M  V30 26 C 0.7636 18.3108 0.0 0
M  V30 27 C -1.8293 20.4421 0.0 0
M  V30 28 C -2.1134 15.9487 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 10 11
M  V30 10 1 10 12
M  V30 11 1 10 13
M  V30 12 1 10 14
M  V30 13 1 11 15
M  V30 14 1 12 16
M  V30 15 1 13 17
M  V30 16 1 15 18
M  V30 17 1 16 19
M  V30 18 1 17 20
M  V30 19 1 21 22
M  V30 20 1 21 23
M  V30 21 1 21 24
M  V30 22 1 21 25
M  V30 23 1 22 26
M  V30 24 1 23 27
M  V30 25 1 24 28
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000750A1-20220106-C00007

>  <Row No>
699

$$$$
US20220000750A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 56 52 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.2323 -0.6702 0.0 0
M  V30 3 O 0.9945 1.1026 0.0 0
M  V30 4 O -1.1026 -0.9945 0.0 0
M  V30 5 C -1.362 0.7999 0.0 0
M  V30 6 C 2.4646 0.1297 0.0 0
M  V30 7 C -0.108 2.2268 0.0 0
M  V30 8 C -0.4107 -2.2052 0.0 0
M  V30 9 C -2.724 0.1297 0.0 0
M  V30 10 C 3.6753 -0.5621 0.0 0
M  V30 11 C 0.8864 3.351 0.0 0
M  V30 12 C 0.9296 -1.7295 0.0 0
M  V30 13 C -4.0861 0.9296 0.0 0
M  V30 14 C -5.4481 0.2594 0.0 0
M  V30 15 C -6.8102 1.0593 0.0 0
M  V30 16 C -8.1722 0.3891 0.0 0
M  V30 17 Si 2.0754 -10.8963 0.0 0
M  V30 18 O 3.3078 -11.5665 0.0 0
M  V30 19 O 3.0699 -9.772 0.0 0
M  V30 20 O 0.9512 -11.8908 0.0 0
M  V30 21 C 0.735 -10.0747 0.0 0
M  V30 22 C 4.5401 -10.7666 0.0 0
M  V30 23 C 1.9673 -8.6478 0.0 0
M  V30 24 C 1.643 -13.1015 0.0 0
M  V30 25 C -0.6269 -10.7666 0.0 0
M  V30 26 C -1.989 -9.9666 0.0 0
M  V30 27 C -3.351 -10.6368 0.0 0
M  V30 28 C -4.713 -9.8369 0.0 0
M  V30 29 C -6.0751 -10.5071 0.0 0
M  V30 30 C -7.4371 -9.7072 0.0 0
M  V30 31 C -8.7775 -10.399 0.0 0
M  V30 32 Si -0.5188 11.7611 0.0 0
M  V30 33 O 0.4756 12.8853 0.0 0
M  V30 34 O -1.643 10.7666 0.0 0
M  V30 35 O 0.7134 11.0908 0.0 0
M  V30 36 C -1.8592 12.5826 0.0 0
M  V30 37 C -0.6269 14.0095 0.0 0
M  V30 38 C -0.9512 9.5558 0.0 0
M  V30 39 C 1.9241 11.9124 0.0 0
M  V30 40 C -3.2213 11.8908 0.0 0
M  V30 41 C -4.5833 12.6907 0.0 0
M  V30 42 C -5.9454 12.0205 0.0 0
M  V30 43 C -7.3074 12.8204 0.0 0
M  V30 44 C -8.6694 12.1502 0.0 0
M  V30 45 Si -5.7075 22.1385 0.0 0
M  V30 46 O -4.7347 23.2627 0.0 0
M  V30 47 O -6.8318 21.144 0.0 0
M  V30 48 O -4.4968 21.4467 0.0 0
M  V30 49 C -7.0696 22.9384 0.0 0
M  V30 50 C -5.8373 24.4086 0.0 0
M  V30 51 C -6.1399 19.9333 0.0 0
M  V30 52 C -3.2645 22.2466 0.0 0
M  V30 53 C -8.4316 22.2682 0.0 0
M  V30 54 C -4.8211 25.5112 0.0 0
M  V30 55 C -4.7563 19.9982 0.0 0
M  V30 56 C -2.0322 21.5764 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 17 18
M  V30 17 1 17 19
M  V30 18 1 17 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 25 26
M  V30 25 1 26 27
M  V30 26 1 27 28
M  V30 27 1 28 29
M  V30 28 1 29 30
M  V30 29 1 30 31
M  V30 30 1 32 33
M  V30 31 1 32 34
M  V30 32 1 32 35
M  V30 33 1 32 36
M  V30 34 1 33 37
M  V30 35 1 34 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 1 40 41
M  V30 39 1 41 42
M  V30 40 1 42 43
M  V30 41 1 43 44
M  V30 42 1 45 46
M  V30 43 1 45 47
M  V30 44 1 45 48
M  V30 45 1 45 49
M  V30 46 1 46 50
M  V30 47 1 47 51
M  V30 48 1 48 52
M  V30 49 1 49 53
M  V30 50 1 50 54
M  V30 51 1 51 55
M  V30 52 1 52 56
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023002.cdx

>  <name>
US20220000750A1-20220106-C00008

>  <Row No>
700

$$$$
US20220000750A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 59 56 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.111 -0.6079 0.0 0
M  V30 3 O 0.9014 1.0272 0.0 0
M  V30 4 O -1.0272 -0.9014 0.0 0
M  V30 5 C -1.2368 0.7547 0.0 0
M  V30 6 C 2.2221 0.1467 0.0 0
M  V30 7 C -0.1048 2.0544 0.0 0
M  V30 8 C -0.3983 -2.0125 0.0 0
M  V30 9 C -2.4737 0.1257 0.0 0
M  V30 10 C 3.3332 -0.4612 0.0 0
M  V30 11 C 0.5031 3.2913 0.0 0
M  V30 12 C 0.8595 -1.6142 0.0 0
M  V30 13 C -3.7315 0.8595 0.0 0
M  V30 14 C -4.9684 0.2515 0.0 0
M  V30 15 C -6.2263 0.9853 0.0 0
M  V30 16 C -7.4631 0.3773 0.0 0
M  V30 17 C -8.721 1.111 0.0 0
M  V30 18 C -9.9579 0.5031 0.0 0
M  V30 19 C -11.1947 1.2368 0.0 0
M  V30 20 C -12.4316 0.6289 0.0 0
M  V30 21 C -13.6685 1.3626 0.0 0
M  V30 22 C -14.9054 0.7337 0.0 0
M  V30 23 Si -3.0188 21.4671 0.0 0
M  V30 24 O -1.9077 22.704 0.0 0
M  V30 25 O -4.2556 20.356 0.0 0
M  V30 26 O -1.6771 20.6914 0.0 0
M  V30 27 C -4.4862 22.3895 0.0 0
M  V30 28 C -3.1236 23.9618 0.0 0
M  V30 29 C -3.48 19.0143 0.0 0
M  V30 30 C -0.3354 21.5929 0.0 0
M  V30 31 C -5.9537 21.6138 0.0 0
M  V30 32 C -1.9915 25.1777 0.0 0
M  V30 33 C -1.9706 19.4965 0.0 0
M  V30 34 C 1.0062 20.7962 0.0 0
M  V30 35 C -7.4422 22.4943 0.0 0
M  V30 36 C -8.9097 21.7187 0.0 0
M  V30 37 C -10.3771 22.5992 0.0 0
M  V30 38 C -11.8446 21.8235 0.0 0
M  V30 39 C -13.3121 22.704 0.0 0
M  V30 40 C -14.7796 21.9283 0.0 0
M  V30 41 Si 0.5031 11.2367 0.0 0
M  V30 42 O 1.4884 12.3268 0.0 0
M  V30 43 O -0.5869 10.2514 0.0 0
M  V30 44 O 1.698 10.5658 0.0 0
M  V30 45 C -0.8175 12.0543 0.0 0
M  V30 46 C 0.3983 13.4379 0.0 0
M  V30 47 C 0.0838 9.0564 0.0 0
M  V30 48 C 2.893 11.3834 0.0 0
M  V30 49 C -2.1383 11.3834 0.0 0
M  V30 50 C -3.48 12.1591 0.0 0
M  V30 51 C -4.8007 11.4882 0.0 0
M  V30 52 C -6.1424 12.2639 0.0 0
M  V30 53 C -7.4631 11.593 0.0 0
M  V30 54 C -8.8048 12.3687 0.0 0
M  V30 55 C -10.1256 11.6979 0.0 0
M  V30 56 C -11.4673 12.4735 0.0 0
M  V30 57 C -12.788 11.8027 0.0 0
M  V30 58 C -14.1297 12.5784 0.0 0
M  V30 59 C -15.4504 11.9075 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 23 24
M  V30 23 1 23 25
M  V30 24 1 23 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 25 29
M  V30 28 1 26 30
M  V30 29 1 27 31
M  V30 30 1 28 32
M  V30 31 1 29 33
M  V30 32 1 30 34
M  V30 33 1 31 35
M  V30 34 1 35 36
M  V30 35 1 36 37
M  V30 36 1 37 38
M  V30 37 1 38 39
M  V30 38 1 39 40
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 41 44
M  V30 42 1 41 45
M  V30 43 1 42 46
M  V30 44 1 43 47
M  V30 45 1 44 48
M  V30 46 1 45 49
M  V30 47 1 49 50
M  V30 48 1 50 51
M  V30 49 1 51 52
M  V30 50 1 52 53
M  V30 51 1 53 54
M  V30 52 1 54 55
M  V30 53 1 55 56
M  V30 54 1 56 57
M  V30 55 1 57 58
M  V30 56 1 58 59
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023003.cdx

>  <name>
US20220000750A1-20220106-C00009

>  <Row No>
701

$$$$
US20220000750A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.4578 0.0358 0.0 0
M  V30 3 O -0.0358 1.5295 0.0 0
M  V30 4 O -0.0358 -1.4578 0.0 0
M  V30 5 C -1.3264 -0.7169 0.0 0
M  V30 6 C 2.1748 1.3622 0.0 0
M  V30 7 C -1.3502 2.3182 0.0 0
M  V30 8 C 1.2069 -2.1867 0.0 0
M  V30 9 C -2.6528 0.0477 0.0 0
M  V30 10 C 3.6326 1.398 0.0 0
M  V30 11 C -1.3861 3.8477 0.0 0
M  V30 12 C 1.171 -3.6446 0.0 0
M  V30 13 C -3.9911 -0.6572 0.0 0
M  V30 14 N -5.3056 0.1314 0.0 0
M  V30 15 Si 8.2212 -5.8313 0.0 0
M  V30 16 O 8.1854 -7.2892 0.0 0
M  V30 17 O 8.1854 -4.3018 0.0 0
M  V30 18 O 9.6791 -5.7955 0.0 0
M  V30 19 C 6.8948 -6.5483 0.0 0
M  V30 20 C 9.4281 -8.0301 0.0 0
M  V30 21 C 6.859 -3.5251 0.0 0
M  V30 22 C 5.5684 -5.7835 0.0 0
M  V30 23 C 9.3923 -9.4879 0.0 0
M  V30 24 C 6.8351 -1.9955 0.0 0
M  V30 25 C 4.242 -6.5005 0.0 0
M  V30 26 N 2.9156 -5.7238 0.0 0
M  V30 27 O -0.2867 9.7508 0.0 0
M  V30 28 C -1.6131 10.5156 0.0 0
M  V30 29 C -2.9395 9.7986 0.0 0
M  V30 30 O 3.9194 0.2867 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 15 16
M  V30 15 1 15 17
M  V30 16 1 15 18
M  V30 17 1 15 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 19 22
M  V30 21 1 20 23
M  V30 22 1 21 24
M  V30 23 1 22 25
M  V30 24 1 25 26
M  V30 25 1 27 28
M  V30 26 1 28 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000750A1-20220106-C00010

>  <Row No>
702

$$$$
US20220000750A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 52 44 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -0.0392 1.5309 0.0 0
M  V30 3 O 1.4524 0.0392 0.0 0
M  V30 4 O -0.0392 -1.4524 0.0 0
M  V30 5 C -1.3346 -0.7196 0.0 0
M  V30 6 C -1.3608 2.3552 0.0 0
M  V30 7 C 2.172 1.3739 0.0 0
M  V30 8 C 1.2038 -2.1851 0.0 0
M  V30 9 C -2.6693 0.0785 0.0 0
M  V30 10 C -1.4 3.8862 0.0 0
M  V30 11 C 3.6245 1.4131 0.0 0
M  V30 12 C 1.1645 -3.6375 0.0 0
M  V30 13 C -4.0039 -0.628 0.0 0
M  V30 14 N -5.3255 0.1831 0.0 0
M  V30 15 Si -0.314 13.3989 0.0 0
M  V30 16 O 1.1383 13.4381 0.0 0
M  V30 17 O -0.3532 14.9298 0.0 0
M  V30 18 O -0.3532 11.9464 0.0 0
M  V30 19 C -1.6486 12.6792 0.0 0
M  V30 20 C 1.858 14.7728 0.0 0
M  V30 21 C -1.6748 15.7541 0.0 0
M  V30 22 C 0.8897 11.2137 0.0 0
M  V30 23 C -2.9833 13.4774 0.0 0
M  V30 24 C 3.3104 14.812 0.0 0
M  V30 25 C -1.7141 17.2851 0.0 0
M  V30 26 C 0.8505 9.7613 0.0 0
M  V30 27 C -4.318 12.7708 0.0 0
M  V30 28 N -5.6395 13.5821 0.0 0
M  V30 29 Si 7.6415 -5.862 0.0 0
M  V30 30 O 7.6023 -7.3144 0.0 0
M  V30 31 O 9.0939 -5.8227 0.0 0
M  V30 32 O 7.6023 -4.331 0.0 0
M  V30 33 C 6.3069 -6.5816 0.0 0
M  V30 34 C 8.8453 -8.0472 0.0 0
M  V30 35 C 4.9722 -5.7835 0.0 0
M  V30 36 C 8.8061 -9.4996 0.0 0
M  V30 37 C 3.6375 -6.5031 0.0 0
M  V30 38 N 2.3029 -5.705 0.0 0
M  V30 39 Si 6.4901 7.2228 0.0 0
M  V30 40 O 6.4508 5.7704 0.0 0
M  V30 41 O 7.9425 7.2621 0.0 0
M  V30 42 O 6.4508 8.7537 0.0 0
M  V30 43 C 5.1554 6.5031 0.0 0
M  V30 44 C 7.6939 5.0376 0.0 0
M  V30 45 C 3.8207 7.3013 0.0 0
M  V30 46 C 7.6546 3.5852 0.0 0
M  V30 47 C 2.4861 6.5816 0.0 0
M  V30 48 N 1.1514 7.3798 0.0 0
M  V30 49 C 11.724 -5.862 0.0 0
M  V30 50 C 3.8731 0.314 0.0 0
M  V30 51 C 10.5725 7.2228 0.0 0
M  V30 52 C 3.8731 13.3989 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 15 16
M  V30 15 1 15 17
M  V30 16 1 15 18
M  V30 17 1 15 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 23 27
M  V30 26 1 27 28
M  V30 27 1 29 30
M  V30 28 1 29 31
M  V30 29 1 29 32
M  V30 30 1 29 33
M  V30 31 1 30 34
M  V30 32 1 33 35
M  V30 33 1 34 36
M  V30 34 1 35 37
M  V30 35 1 37 38
M  V30 36 1 39 40
M  V30 37 1 39 41
M  V30 38 1 39 42
M  V30 39 1 39 43
M  V30 40 1 40 44
M  V30 41 1 43 45
M  V30 42 1 44 46
M  V30 43 1 45 47
M  V30 44 1 47 48
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000750A1-20220106-C00011

>  <Row No>
703

$$$$
US20220000750A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 48 44 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -0.0756 -1.4114 0.0 0
M  V30 3 O 1.4114 0.0756 0.0 0
M  V30 4 O -0.0756 1.5626 0.0 0
M  V30 5 C -1.361 -0.6552 0.0 0
M  V30 6 C 1.1341 -2.0919 0.0 0
M  V30 7 C 2.0667 1.4366 0.0 0
M  V30 8 C -1.4366 2.3943 0.0 0
M  V30 9 C -2.722 0.1512 0.0 0
M  V30 10 C 1.0585 -3.5033 0.0 0
M  V30 11 C 3.4781 1.5122 0.0 0
M  V30 12 C -1.5122 3.9569 0.0 0
M  V30 13 C -4.083 -0.504 0.0 0
M  V30 14 N -5.444 0.3276 0.0 0
M  V30 15 Si 6.6538 -25.4054 0.0 0
M  V30 16 O 5.0911 -25.3298 0.0 0
M  V30 17 O 8.3928 -25.3298 0.0 0
M  V30 18 O 6.5781 -23.8428 0.0 0
M  V30 19 C 6.5781 -26.8168 0.0 0
M  V30 20 Si 3.2008 -25.2542 0.0 0
M  V30 21 C 9.0481 -23.9688 0.0 0
M  V30 22 C 7.7879 -27.4721 0.0 0
M  V30 23 O 3.1252 -23.6915 0.0 0
M  V30 24 C 3.1252 -26.6656 0.0 0
M  V30 25 C 1.6382 -25.1786 0.0 0
M  V30 26 C 10.4595 -23.8932 0.0 0
M  V30 27 C 7.7123 -28.8835 0.0 0
M  V30 28 C 1.7642 -22.885 0.0 0
M  V30 29 C 4.335 -27.3209 0.0 0
M  V30 30 N 8.9221 -29.5388 0.0 0
M  V30 31 C 1.6886 -21.3224 0.0 0
M  V30 32 C 4.2594 -28.7323 0.0 0
M  V30 33 N 5.4692 -29.3876 0.0 0
M  V30 34 Si 3.8309 -10.888 0.0 0
M  V30 35 O 3.7553 -12.2994 0.0 0
M  V30 36 O 5.2423 -10.8124 0.0 0
M  V30 37 O 3.7553 -9.3254 0.0 0
M  V30 38 C 2.4699 -11.5433 0.0 0
M  V30 39 C 4.9651 -12.9799 0.0 0
M  V30 40 C 5.8976 -9.4514 0.0 0
M  V30 41 C 1.1089 -10.7368 0.0 0
M  V30 42 C 4.8895 -14.3913 0.0 0
M  V30 43 C 7.3091 -9.3758 0.0 0
M  V30 44 C -0.252 -11.3921 0.0 0
M  V30 45 N -1.613 -10.5603 0.0 0
M  V30 46 O -0.6048 -11.0896 0.0 0
M  V30 47 C -1.9658 -10.2831 0.0 0
M  V30 48 C -3.3269 -10.9384 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 15 16
M  V30 15 1 15 17
M  V30 16 1 15 18
M  V30 17 1 15 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 19 22
M  V30 21 1 20 23
M  V30 22 1 20 24
M  V30 23 1 20 25
M  V30 24 1 21 26
M  V30 25 1 22 27
M  V30 26 1 23 28
M  V30 27 1 24 29
M  V30 28 1 27 30
M  V30 29 1 28 31
M  V30 30 1 29 32
M  V30 31 1 32 33
M  V30 32 1 34 35
M  V30 33 1 34 36
M  V30 34 1 34 37
M  V30 35 1 34 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 1 38 41
M  V30 39 1 39 42
M  V30 40 1 40 43
M  V30 41 1 41 44
M  V30 42 1 44 45
M  V30 43 1 46 47
M  V30 44 1 47 48
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000750A1-20220106-C00012

>  <Row No>
704

$$$$
US20220000750A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.6573 0.0394 0.0 0
M  V30 3 C -1.4863 0.0394 0.0 0
M  V30 4 C -0.0394 1.4863 0.0 0
M  V30 5 C -0.0394 -1.4074 0.0 0
M  V30 6 Si 3.0647 0.0789 0.0 0
M  V30 7 C 3.0252 1.5652 0.0 0
M  V30 8 C 3.0252 -1.3284 0.0 0
M  V30 9 C 4.722 0.1183 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 6 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000750A1-20220106-C00013

>  <Row No>
705

$$$$
US20220000750A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.4757 0.0406 0.0 0
M  V30 3 O 1.6517 0.0406 0.0 0
M  V30 4 C -0.0406 1.4757 0.0 0
M  V30 5 C -0.0406 -1.3945 0.0 0
M  V30 6 Si -3.2087 0.0812 0.0 0
M  V30 7 Si 3.0462 0.0812 0.0 0
M  V30 8 C -4.6845 0.1218 0.0 0
M  V30 9 C -3.2493 1.5569 0.0 0
M  V30 10 C -3.2493 -1.3132 0.0 0
M  V30 11 C 3.0056 1.5569 0.0 0
M  V30 12 C 3.0056 -1.3132 0.0 0
M  V30 13 C 4.698 0.1218 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 1 7 13
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000750A1-20220106-C00014

>  <Row No>
706

$$$$
US20220000750A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 17 16 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.6573 0.0407 0.0 0
M  V30 3 O -1.4807 0.0407 0.0 0
M  V30 4 C -0.0407 1.4807 0.0 0
M  V30 5 C -0.0407 -1.3992 0.0 0
M  V30 6 Si 3.0566 0.0815 0.0 0
M  V30 7 Si -3.2196 0.0815 0.0 0
M  V30 8 O 4.7139 0.1222 0.0 0
M  V30 9 C 3.0158 1.5622 0.0 0
M  V30 10 C 3.0158 -1.3177 0.0 0
M  V30 11 C -4.7004 0.1222 0.0 0
M  V30 12 C -3.2603 1.5622 0.0 0
M  V30 13 C -3.2603 -1.3177 0.0 0
M  V30 14 Si 6.1132 0.163 0.0 0
M  V30 15 C 6.0724 1.6437 0.0 0
M  V30 16 C 6.0724 -1.2362 0.0 0
M  V30 17 C 7.7706 0.2037 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 1 7 13
M  V30 13 1 8 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000750A1-20220106-C00015

>  <Row No>
707

$$$$
US20220000751A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 48 44 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.1206 -0.9961 0.0 0
M  V30 3 O 1.2451 -0.6848 0.0 0
M  V30 4 O 0.9961 1.1206 0.0 0
M  V30 5 C -1.3489 0.8093 0.0 0
M  V30 6 C -0.4358 -2.2413 0.0 0
M  V30 7 C 2.4903 0.1245 0.0 0
M  V30 8 C -0.1245 2.2413 0.0 0
M  V30 9 C -2.6979 0.1245 0.0 0
M  V30 10 C 0.9131 -1.7847 0.0 0
M  V30 11 C 3.7355 -0.5603 0.0 0
M  V30 12 C -1.5979 1.9092 0.0 0
M  V30 13 N -4.0468 0.9338 0.0 0
M  V30 14 Si 0.8301 21.2513 0.0 0
M  V30 15 O -0.2905 20.2551 0.0 0
M  V30 16 O 2.0753 20.5664 0.0 0
M  V30 17 O 1.8262 22.3719 0.0 0
M  V30 18 C -0.498 22.0606 0.0 0
M  V30 19 C 0.3943 19.0099 0.0 0
M  V30 20 C 3.3205 21.3758 0.0 0
M  V30 21 C 0.7056 23.4926 0.0 0
M  V30 22 C -1.847 21.3758 0.0 0
M  V30 23 C 1.7432 19.4665 0.0 0
M  V30 24 C 4.5657 20.6909 0.0 0
M  V30 25 C -0.7678 23.1606 0.0 0
M  V30 26 C -3.1959 22.1852 0.0 0
M  V30 27 N -4.5449 21.5003 0.0 0
M  V30 28 Si 9.9615 0.498 0.0 0
M  V30 29 O 8.8408 -0.498 0.0 0
M  V30 30 O 11.2067 -0.1867 0.0 0
M  V30 31 O 10.9577 1.6187 0.0 0
M  V30 32 C 8.6125 1.3074 0.0 0
M  V30 33 C 9.5257 -1.7432 0.0 0
M  V30 34 C 12.4519 0.6225 0.0 0
M  V30 35 C 9.837 2.7394 0.0 0
M  V30 36 C 7.2636 0.6225 0.0 0
M  V30 37 N 5.9146 1.4319 0.0 0
M  V30 38 Si 0.9961 10.7916 0.0 0
M  V30 39 O -0.1245 9.7955 0.0 0
M  V30 40 O 2.2413 10.1068 0.0 0
M  V30 41 O 1.9923 11.9123 0.0 0
M  V30 42 C -0.3528 11.601 0.0 0
M  V30 43 C 0.5603 8.5503 0.0 0
M  V30 44 C 3.4865 10.9162 0.0 0
M  V30 45 C 0.8716 13.033 0.0 0
M  V30 46 C -1.7017 10.9162 0.0 0
M  V30 47 C -3.0507 11.7255 0.0 0
M  V30 48 N -4.3996 11.0407 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 14 15
M  V30 14 1 14 16
M  V30 15 1 14 17
M  V30 16 1 14 18
M  V30 17 1 15 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 26 27
M  V30 26 1 28 29
M  V30 27 1 28 30
M  V30 28 1 28 31
M  V30 29 1 28 32
M  V30 30 1 29 33
M  V30 31 1 30 34
M  V30 32 1 31 35
M  V30 33 1 32 36
M  V30 34 1 36 37
M  V30 35 1 38 39
M  V30 36 1 38 40
M  V30 37 1 38 41
M  V30 38 1 38 42
M  V30 39 1 39 43
M  V30 40 1 40 44
M  V30 41 1 41 45
M  V30 42 1 42 46
M  V30 43 1 46 47
M  V30 44 1 47 48
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000751A1-20220106-C00001

>  <Row No>
708

$$$$
US20220000751A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 56 52 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.1206 -0.9678 0.0 0
M  V30 3 O 1.2225 -0.6622 0.0 0
M  V30 4 O 0.9678 1.1206 0.0 0
M  V30 5 C -1.3753 0.815 0.0 0
M  V30 6 C -0.4584 -2.1903 0.0 0
M  V30 7 C 2.445 0.1528 0.0 0
M  V30 8 C -0.1528 2.2413 0.0 0
M  V30 9 C -2.7507 0.1528 0.0 0
M  V30 10 C 0.8914 -1.7319 0.0 0
M  V30 11 C 3.6676 -0.5093 0.0 0
M  V30 12 C -1.6555 1.9356 0.0 0
M  V30 13 N -4.126 0.9678 0.0 0
M  V30 14 C -5.5014 0.3056 0.0 0
M  V30 15 C -4.2024 2.5214 0.0 0
M  V30 16 Si 0.2037 26.0807 0.0 0
M  V30 17 O -0.9169 25.1129 0.0 0
M  V30 18 O 1.4262 25.4185 0.0 0
M  V30 19 O 1.1715 27.2014 0.0 0
M  V30 20 C -1.1715 26.8957 0.0 0
M  V30 21 C -0.2546 23.8903 0.0 0
M  V30 22 C 2.6488 26.2335 0.0 0
M  V30 23 C 0.0509 28.322 0.0 0
M  V30 24 C -2.5469 26.2335 0.0 0
M  V30 25 C 1.0951 24.3488 0.0 0
M  V30 26 C 3.8713 25.5713 0.0 0
M  V30 27 C -1.4517 28.0164 0.0 0
M  V30 28 C -3.9223 27.0486 0.0 0
M  V30 29 N -5.2976 26.3864 0.0 0
M  V30 30 C -6.673 27.2014 0.0 0
M  V30 31 C -5.374 24.9855 0.0 0
M  V30 32 Si 0.2037 -8.1502 0.0 0
M  V30 33 O -0.9169 -9.118 0.0 0
M  V30 34 O 1.4262 -8.8124 0.0 0
M  V30 35 O 1.1715 -7.0295 0.0 0
M  V30 36 C -1.1715 -7.3352 0.0 0
M  V30 37 C -0.2546 -10.3406 0.0 0
M  V30 38 C 2.6488 -7.9974 0.0 0
M  V30 39 C 0.0509 -5.9089 0.0 0
M  V30 40 C -2.5469 -7.9974 0.0 0
M  V30 41 N -3.9223 -7.1823 0.0 0
M  V30 42 C -5.2976 -7.8446 0.0 0
M  V30 43 C -3.9987 -5.6287 0.0 0
M  V30 44 Si 1.0187 16.0967 0.0 0
M  V30 45 O -0.1018 15.1288 0.0 0
M  V30 46 O 2.2413 15.4345 0.0 0
M  V30 47 O 1.9866 17.2173 0.0 0
M  V30 48 C -0.3565 16.9117 0.0 0
M  V30 49 C 0.5603 13.9063 0.0 0
M  V30 50 C 3.4638 16.2495 0.0 0
M  V30 51 C 0.8659 18.338 0.0 0
M  V30 52 C -1.7319 16.2495 0.0 0
M  V30 53 C -3.1072 17.0645 0.0 0
M  V30 54 N -4.4826 16.4023 0.0 0
M  V30 55 C -5.8579 17.2173 0.0 0
M  V30 56 C -4.559 15.0015 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 15 1 16 17
M  V30 16 1 16 18
M  V30 17 1 16 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 28 29
M  V30 28 1 29 30
M  V30 29 1 29 31
M  V30 30 1 32 33
M  V30 31 1 32 34
M  V30 32 1 32 35
M  V30 33 1 32 36
M  V30 34 1 33 37
M  V30 35 1 34 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 1 40 41
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 44 45
M  V30 42 1 44 46
M  V30 43 1 44 47
M  V30 44 1 44 48
M  V30 45 1 45 49
M  V30 46 1 46 50
M  V30 47 1 47 51
M  V30 48 1 48 52
M  V30 49 1 52 53
M  V30 50 1 53 54
M  V30 51 1 54 55
M  V30 52 1 54 56
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024002.cdx

>  <name>
US20220000751A1-20220106-C00002

>  <Row No>
709

$$$$
US20220000751A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 152 146 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.4598 -0.6122 0.0 0
M  V30 3 O 0.6122 -1.1773 0.0 0
M  V30 4 O -0.8947 1.4598 0.0 0
M  V30 5 C 1.1773 0.8947 0.0 0
M  V30 6 C -2.9197 0.2825 0.0 0
M  V30 7 C 1.9779 -1.036 0.0 0
M  V30 8 C -0.6593 3.061 0.0 0
M  V30 9 C 2.3546 0.2825 0.0 0
M  V30 10 C -4.3796 -0.3296 0.0 0
M  V30 11 C 2.5901 -2.2133 0.0 0
M  V30 12 C 0.7063 3.2023 0.0 0
M  V30 13 C 3.5319 1.1773 0.0 0
M  V30 14 N 4.7093 0.5651 0.0 0
M  V30 15 C 4.568 -0.8005 0.0 0
M  V30 16 C 5.8866 1.4598 0.0 0
M  V30 17 C 5.7453 -1.4127 0.0 0
M  V30 18 C 7.0639 0.8476 0.0 0
M  V30 19 O 5.604 -2.7784 0.0 0
M  V30 20 C 8.2413 1.7424 0.0 0
M  V30 21 Si 9.4186 1.1302 0.0 0
M  V30 22 O 10.3134 2.3546 0.0 0
M  V30 23 O 8.1942 0.1883 0.0 0
M  V30 24 O 10.5959 0.518 0.0 0
M  V30 25 C 9.136 3.5319 0.0 0
M  V30 26 C 8.0529 -1.1773 0.0 0
M  V30 27 C 11.9616 0.6593 0.0 0
M  V30 28 C 10.0308 4.7564 0.0 0
M  V30 29 C 9.3715 -1.4127 0.0 0
M  V30 30 C 12.9035 1.8837 0.0 0
M  V30 31 Si -1.1302 19.5907 0.0 0
M  V30 32 O -2.5901 18.9785 0.0 0
M  V30 33 O -0.518 18.4134 0.0 0
M  V30 34 O -2.025 21.0506 0.0 0
M  V30 35 C 0.047 20.4855 0.0 0
M  V30 36 C -4.05 19.8733 0.0 0
M  V30 37 C 0.8476 18.5547 0.0 0
M  V30 38 C -1.7895 22.6518 0.0 0
M  V30 39 C 1.2244 19.8733 0.0 0
M  V30 40 C -5.5099 19.2611 0.0 0
M  V30 41 C 1.4598 17.3773 0.0 0
M  V30 42 C -0.4238 22.7931 0.0 0
M  V30 43 C 2.4017 20.7681 0.0 0
M  V30 44 N 3.579 20.1558 0.0 0
M  V30 45 C 4.7564 21.0506 0.0 0
M  V30 46 C 3.4378 18.7901 0.0 0
M  V30 47 C 5.9337 20.4384 0.0 0
M  V30 48 C 7.111 21.3332 0.0 0
M  V30 49 Si 8.2884 20.721 0.0 0
M  V30 50 O 9.1831 21.9454 0.0 0
M  V30 51 O 7.0639 19.8262 0.0 0
M  V30 52 O 9.4657 20.1087 0.0 0
M  V30 53 C 8.0058 23.1698 0.0 0
M  V30 54 C 6.9227 18.4605 0.0 0
M  V30 55 C 10.8314 20.25 0.0 0
M  V30 56 C 8.9006 24.3471 0.0 0
M  V30 57 C 8.2413 18.225 0.0 0
M  V30 58 C 11.7733 21.4745 0.0 0
M  V30 59 Si -1.1302 37.6745 0.0 0
M  V30 60 O -2.5901 37.0623 0.0 0
M  V30 61 O -2.025 39.1344 0.0 0
M  V30 62 O -0.518 36.4972 0.0 0
M  V30 63 C 0.047 38.5693 0.0 0
M  V30 64 C -4.05 37.9571 0.0 0
M  V30 65 C -1.7895 40.7356 0.0 0
M  V30 66 C 0.8476 36.6385 0.0 0
M  V30 67 C 1.2244 37.9571 0.0 0
M  V30 68 C -5.5099 37.3449 0.0 0
M  V30 69 C -0.4238 40.8769 0.0 0
M  V30 70 C 1.4598 35.4611 0.0 0
M  V30 71 C 2.4017 38.8518 0.0 0
M  V30 72 N 3.579 38.2396 0.0 0
M  V30 73 C 4.7564 39.1344 0.0 0
M  V30 74 C 5.9337 38.5222 0.0 0
M  V30 75 C 7.111 39.417 0.0 0
M  V30 76 Si 8.2884 38.8048 0.0 0
M  V30 77 O 7.0639 37.8629 0.0 0
M  V30 78 O 9.4657 38.1925 0.0 0
M  V30 79 O 9.1831 39.9821 0.0 0
M  V30 80 C 6.9227 36.4972 0.0 0
M  V30 81 C 10.8314 38.3338 0.0 0
M  V30 82 C 8.0058 41.2065 0.0 0
M  V30 83 C 8.2413 36.2617 0.0 0
M  V30 84 C 11.7733 39.5111 0.0 0
M  V30 85 C 8.9006 42.4309 0.0 0
M  V30 86 Si 7.9116 10.9256 0.0 0
M  V30 87 O 6.6872 9.9837 0.0 0
M  V30 88 O 9.0889 10.3134 0.0 0
M  V30 89 O 8.8535 12.1029 0.0 0
M  V30 90 C 6.4517 11.8203 0.0 0
M  V30 91 C 6.5459 8.618 0.0 0
M  V30 92 C 10.4546 10.4546 0.0 0
M  V30 93 C 7.629 13.3273 0.0 0
M  V30 94 C 4.9918 11.2081 0.0 0
M  V30 95 C 3.5319 12.1029 0.0 0
M  V30 96 N 2.0721 11.4907 0.0 0
M  V30 97 C 1.9308 10.125 0.0 0
M  V30 98 C 0.6122 12.3855 0.0 0
M  V30 99 C 3.2494 9.8895 0.0 0
M  V30 100 C -0.8476 11.7733 0.0 0
M  V30 101 O 3.1081 8.5238 0.0 0
M  V30 102 C -2.3075 12.668 0.0 0
M  V30 103 Si -3.7674 12.0558 0.0 0
M  V30 104 O -5.2273 11.4436 0.0 0
M  V30 105 O -4.6622 13.5157 0.0 0
M  V30 106 O -3.1552 10.8785 0.0 0
M  V30 107 C -6.6872 12.3384 0.0 0
M  V30 108 C -4.4267 15.1169 0.0 0
M  V30 109 C -1.7895 11.0198 0.0 0
M  V30 110 Si 8.2884 28.6326 0.0 0
M  V30 111 O 7.0639 27.7378 0.0 0
M  V30 112 O 9.4657 28.0204 0.0 0
M  V30 113 O 9.2302 29.857 0.0 0
M  V30 114 C 6.8285 29.5274 0.0 0
M  V30 115 C 6.9227 26.3721 0.0 0
M  V30 116 C 10.8314 28.1617 0.0 0
M  V30 117 C 8.0058 31.0815 0.0 0
M  V30 118 C 5.3686 28.9152 0.0 0
M  V30 119 C 3.9087 29.8099 0.0 0
M  V30 120 N 2.4488 29.1977 0.0 0
M  V30 121 C 0.9889 30.0925 0.0 0
M  V30 122 C 2.3075 27.832 0.0 0
M  V30 123 C -0.4709 29.4803 0.0 0
M  V30 124 C -1.9308 30.3751 0.0 0
M  V30 125 Si -3.3907 29.7629 0.0 0
M  V30 126 O -4.8506 29.1506 0.0 0
M  V30 127 O -4.2854 31.2227 0.0 0
M  V30 128 O -2.7784 28.5855 0.0 0
M  V30 129 C -6.3104 30.0454 0.0 0
M  V30 130 C -4.05 32.8239 0.0 0
M  V30 131 C -1.4127 28.7268 0.0 0
M  V30 132 Si 8.6651 48.2234 0.0 0
M  V30 133 O 7.4878 47.3286 0.0 0
M  V30 134 O 9.8424 47.6112 0.0 0
M  V30 135 O 9.607 49.4478 0.0 0
M  V30 136 C 7.2052 49.1182 0.0 0
M  V30 137 C 7.3465 45.9629 0.0 0
M  V30 138 C 11.2081 47.7525 0.0 0
M  V30 139 C 8.3825 50.6722 0.0 0
M  V30 140 C 5.7453 48.506 0.0 0
M  V30 141 C 4.2854 49.4007 0.0 0
M  V30 142 N 2.8255 48.7885 0.0 0
M  V30 143 C 1.3657 49.6833 0.0 0
M  V30 144 C -0.0941 49.0711 0.0 0
M  V30 145 C -1.554 49.9658 0.0 0
M  V30 146 Si -3.0139 49.3536 0.0 0
M  V30 147 O -4.4738 48.7414 0.0 0
M  V30 148 O -3.9087 50.8135 0.0 0
M  V30 149 O -2.4017 48.1763 0.0 0
M  V30 150 C -5.9337 49.6362 0.0 0
M  V30 151 C -3.6732 52.4147 0.0 0
M  V30 152 C -1.036 48.3176 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 47 48
M  V30 47 1 48 49
M  V30 48 1 49 50
M  V30 49 1 49 51
M  V30 50 1 49 52
M  V30 51 1 50 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 59 60
M  V30 58 1 59 61
M  V30 59 1 59 62
M  V30 60 1 59 63
M  V30 61 1 60 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 71 72
M  V30 70 1 72 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 75 76
M  V30 74 1 76 77
M  V30 75 1 76 78
M  V30 76 1 76 79
M  V30 77 1 77 80
M  V30 78 1 78 81
M  V30 79 1 79 82
M  V30 80 1 80 83
M  V30 81 1 81 84
M  V30 82 1 82 85
M  V30 83 1 86 87
M  V30 84 1 86 88
M  V30 85 1 86 89
M  V30 86 1 86 90
M  V30 87 1 87 91
M  V30 88 1 88 92
M  V30 89 1 89 93
M  V30 90 1 90 94
M  V30 91 1 94 95
M  V30 92 1 95 96
M  V30 93 1 96 97
M  V30 94 1 96 98
M  V30 95 1 97 99
M  V30 96 1 98 100
M  V30 97 1 99 101
M  V30 98 1 100 102
M  V30 99 1 102 103
M  V30 100 1 103 104
M  V30 101 1 103 105
M  V30 102 1 103 106
M  V30 103 1 104 107
M  V30 104 1 105 108
M  V30 105 1 106 109
M  V30 106 1 110 111
M  V30 107 1 110 112
M  V30 108 1 110 113
M  V30 109 1 110 114
M  V30 110 1 111 115
M  V30 111 1 112 116
M  V30 112 1 113 117
M  V30 113 1 114 118
M  V30 114 1 118 119
M  V30 115 1 119 120
M  V30 116 1 120 121
M  V30 117 1 120 122
M  V30 118 1 121 123
M  V30 119 1 123 124
M  V30 120 1 124 125
M  V30 121 1 125 126
M  V30 122 1 125 127
M  V30 123 1 125 128
M  V30 124 1 126 129
M  V30 125 1 127 130
M  V30 126 1 128 131
M  V30 127 1 132 133
M  V30 128 1 132 134
M  V30 129 1 132 135
M  V30 130 1 132 136
M  V30 131 1 133 137
M  V30 132 1 134 138
M  V30 133 1 135 139
M  V30 134 1 136 140
M  V30 135 1 140 141
M  V30 136 1 141 142
M  V30 137 1 142 143
M  V30 138 1 143 144
M  V30 139 1 144 145
M  V30 140 1 145 146
M  V30 141 1 146 147
M  V30 142 1 146 148
M  V30 143 1 146 149
M  V30 144 1 147 150
M  V30 145 1 148 151
M  V30 146 1 149 152
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000751A1-20220106-C00003

>  <Row No>
710

$$$$
US20220000751A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 179 173 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.2274 -0.9072 0.0 0
M  V30 3 O 1.1206 -0.587 0.0 0
M  V30 4 O 0.9072 1.2274 0.0 0
M  V30 5 C -1.4408 0.9072 0.0 0
M  V30 6 C -1.3875 -2.2413 0.0 0
M  V30 7 C 2.4548 -0.4269 0.0 0
M  V30 8 C -0.3201 2.4548 0.0 0
M  V30 9 C -2.8817 0.3201 0.0 0
M  V30 10 C -0.1067 -2.4548 0.0 0
M  V30 11 C 3.362 0.8004 0.0 0
M  V30 12 C 0.587 3.6822 0.0 0
M  V30 13 C -4.3226 1.2274 0.0 0
M  V30 14 N -5.7635 0.6403 0.0 0
M  V30 15 C -5.9236 -0.6937 0.0 0
M  V30 16 C -7.2043 1.5476 0.0 0
M  V30 17 C -4.8029 -1.2807 0.0 0
M  V30 18 C -8.6452 0.9605 0.0 0
M  V30 19 C -4.963 -2.6149 0.0 0
M  V30 20 C -10.0861 1.8678 0.0 0
M  V30 21 Si -11.527 1.2807 0.0 0
M  V30 22 O -12.4342 2.7216 0.0 0
M  V30 23 O -10.9399 0.16 0.0 0
M  V30 24 O -12.9678 0.6937 0.0 0
M  V30 25 C -12.2207 4.3226 0.0 0
M  V30 26 C -9.6058 0.3201 0.0 0
M  V30 27 C -14.4087 1.6009 0.0 0
M  V30 28 C -10.8866 4.4827 0.0 0
M  V30 29 C -9.0188 -0.8004 0.0 0
M  V30 30 C -15.8496 1.0139 0.0 0
M  V30 31 Si -2.1346 20.4924 0.0 0
M  V30 32 O -3.362 19.5852 0.0 0
M  V30 33 O -1.0139 19.9054 0.0 0
M  V30 34 O -1.2274 21.7198 0.0 0
M  V30 35 C -3.5755 21.3996 0.0 0
M  V30 36 C -3.5221 18.251 0.0 0
M  V30 37 C 0.3201 20.0655 0.0 0
M  V30 38 C -2.4548 22.9472 0.0 0
M  V30 39 C -5.0163 20.8126 0.0 0
M  V30 40 C -2.2413 18.0376 0.0 0
M  V30 41 C 1.2274 21.2929 0.0 0
M  V30 42 C -1.5476 24.1746 0.0 0
M  V30 43 C -6.4572 21.7198 0.0 0
M  V30 44 N -7.8981 21.1328 0.0 0
M  V30 45 C -8.0582 19.7987 0.0 0
M  V30 46 C -9.339 22.04 0.0 0
M  V30 47 C -6.9375 19.2116 0.0 0
M  V30 48 C -10.7798 21.453 0.0 0
M  V30 49 N -7.0976 17.8775 0.0 0
M  V30 50 C -12.2207 22.3602 0.0 0
M  V30 51 Si -13.6616 21.7732 0.0 0
M  V30 52 O -14.5688 23.2141 0.0 0
M  V30 53 O -13.0746 20.6525 0.0 0
M  V30 54 O -15.1025 21.1862 0.0 0
M  V30 55 C -14.3553 24.815 0.0 0
M  V30 56 C -11.7404 20.8126 0.0 0
M  V30 57 C -16.5433 22.0934 0.0 0
M  V30 58 C -13.0212 24.9751 0.0 0
M  V30 59 C -11.1534 19.6919 0.0 0
M  V30 60 C -17.9842 21.5064 0.0 0
M  V30 61 Si -11.527 42.2656 0.0 0
M  V30 62 O -12.9678 41.6786 0.0 0
M  V30 63 O -12.4342 43.7065 0.0 0
M  V30 64 O -10.9399 41.145 0.0 0
M  V30 65 C -10.4063 43.1729 0.0 0
M  V30 66 C -14.4087 42.5858 0.0 0
M  V30 67 C -12.2207 45.3075 0.0 0
M  V30 68 C -12.1673 40.2377 0.0 0
M  V30 69 C -9.2856 42.5858 0.0 0
M  V30 70 C -15.8496 41.9988 0.0 0
M  V30 71 C -10.8866 45.4676 0.0 0
M  V30 72 C -11.9539 38.957 0.0 0
M  V30 73 C -8.1649 43.4931 0.0 0
M  V30 74 N -7.0442 42.906 0.0 0
M  V30 75 C -7.2043 41.5719 0.0 0
M  V30 76 C -5.9236 43.8132 0.0 0
M  V30 77 C -6.0836 40.9849 0.0 0
M  V30 78 C -4.8029 43.2262 0.0 0
M  V30 79 C -6.2437 39.6507 0.0 0
M  V30 80 C -3.6822 44.1334 0.0 0
M  V30 81 Si -7.6846 39.0637 0.0 0
M  V30 82 Si -2.5615 43.5464 0.0 0
M  V30 83 O -9.1255 39.9709 0.0 0
M  V30 84 O -9.1255 38.4767 0.0 0
M  V30 85 O -6.5639 38.4767 0.0 0
M  V30 86 O -3.7889 42.6392 0.0 0
M  V30 87 O -1.4408 42.9594 0.0 0
M  V30 88 O -1.6543 44.7738 0.0 0
M  V30 89 C -9.2856 41.6253 0.0 0
M  V30 90 C -10.5664 39.3839 0.0 0
M  V30 91 C -5.2832 39.0103 0.0 0
M  V30 92 C -3.949 41.3051 0.0 0
M  V30 93 C -0.1067 43.1195 0.0 0
M  V30 94 C -2.8817 46.0012 0.0 0
M  V30 95 C -10.7265 42.5325 0.0 0
M  V30 96 C -11.7938 38.4767 0.0 0
M  V30 97 C -4.3759 38.1031 0.0 0
M  V30 98 C -2.6149 41.4652 0.0 0
M  V30 99 C 0.1067 44.7205 0.0 0
M  V30 100 C -4.4827 45.7878 0.0 0
M  V30 101 Si -2.5615 11.1 0.0 0
M  V30 102 O -3.7889 10.1928 0.0 0
M  V30 103 O -1.4408 10.513 0.0 0
M  V30 104 O -1.6543 12.3274 0.0 0
M  V30 105 C -4.0024 12.0072 0.0 0
M  V30 106 C -3.949 8.8587 0.0 0
M  V30 107 C -0.1067 10.6731 0.0 0
M  V30 108 C -2.8817 13.5549 0.0 0
M  V30 109 C -5.4433 11.4202 0.0 0
M  V30 110 C -6.8841 12.3274 0.0 0
M  V30 111 N -8.325 11.7404 0.0 0
M  V30 112 C -8.4851 10.4063 0.0 0
M  V30 113 C -9.7659 12.6476 0.0 0
M  V30 114 C -7.2043 10.1928 0.0 0
M  V30 115 C -11.2068 12.0606 0.0 0
M  V30 116 C -7.3644 8.8587 0.0 0
M  V30 117 C -12.6476 12.9678 0.0 0
M  V30 118 Si -14.0885 12.3808 0.0 0
M  V30 119 O -15.5294 11.7938 0.0 0
M  V30 120 O -14.9957 13.8217 0.0 0
M  V30 121 O -13.5015 11.2601 0.0 0
M  V30 122 C -16.9703 12.701 0.0 0
M  V30 123 C -14.7823 15.4227 0.0 0
M  V30 124 C -12.1673 11.4202 0.0 0
M  V30 125 Si -2.5615 29.8848 0.0 0
M  V30 126 O -3.7889 28.9776 0.0 0
M  V30 127 O -1.4408 29.2978 0.0 0
M  V30 128 O -1.6543 31.1122 0.0 0
M  V30 129 C -4.0024 30.792 0.0 0
M  V30 130 C -3.949 27.6434 0.0 0
M  V30 131 C -0.1067 29.4579 0.0 0
M  V30 132 C -2.8817 32.3396 0.0 0
M  V30 133 C -5.4433 30.205 0.0 0
M  V30 134 C -6.8841 31.1122 0.0 0
M  V30 135 N -8.325 30.5252 0.0 0
M  V30 136 C -8.4851 29.191 0.0 0
M  V30 137 C -9.7659 31.4324 0.0 0
M  V30 138 C -7.2043 28.9776 0.0 0
M  V30 139 C -11.2068 30.8454 0.0 0
M  V30 140 N -7.3644 27.6434 0.0 0
M  V30 141 C -12.6476 31.7526 0.0 0
M  V30 142 Si -14.0885 31.1656 0.0 0
M  V30 143 O -15.5294 30.5785 0.0 0
M  V30 144 O -14.9957 32.6064 0.0 0
M  V30 145 O -13.5015 30.0449 0.0 0
M  V30 146 C -16.9703 31.4858 0.0 0
M  V30 147 C -14.7823 34.2074 0.0 0
M  V30 148 C -12.1673 30.205 0.0 0
M  V30 149 Si -2.5615 54.6465 0.0 0
M  V30 150 O -3.7889 53.7393 0.0 0
M  V30 151 O -1.4408 54.0595 0.0 0
M  V30 152 O -1.6543 55.8739 0.0 0
M  V30 153 C -4.0024 55.5537 0.0 0
M  V30 154 C -3.949 52.4051 0.0 0
M  V30 155 C -0.1067 54.2196 0.0 0
M  V30 156 C -2.8817 57.1013 0.0 0
M  V30 157 C -5.4433 54.9667 0.0 0
M  V30 158 C -6.8841 55.8739 0.0 0
M  V30 159 N -8.325 55.2869 0.0 0
M  V30 160 C -9.7659 56.1941 0.0 0
M  V30 161 C -8.4851 53.9527 0.0 0
M  V30 162 C -11.2068 55.6071 0.0 0
M  V30 163 C -7.3644 53.3657 0.0 0
M  V30 164 C -12.6476 56.5143 0.0 0
M  V30 165 C -7.5245 52.0316 0.0 0
M  V30 166 Si -14.0885 55.9273 0.0 0
M  V30 167 Si -8.9654 51.4446 0.0 0
M  V30 168 O -15.5294 55.3403 0.0 0
M  V30 169 O -14.9957 57.3682 0.0 0
M  V30 170 O -13.5015 54.8066 0.0 0
M  V30 171 O -10.4063 52.3518 0.0 0
M  V30 172 O -10.4063 50.8575 0.0 0
M  V30 173 O -7.8447 50.8575 0.0 0
M  V30 174 C -16.9703 56.2475 0.0 0
M  V30 175 C -14.7823 58.9691 0.0 0
M  V30 176 C -12.1673 54.9667 0.0 0
M  V30 177 C -10.5664 54.0061 0.0 0
M  V30 178 C -11.8472 51.7647 0.0 0
M  V30 179 C -6.5639 51.3912 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 1 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 31 32
M  V30 31 1 31 33
M  V30 32 1 31 34
M  V30 33 1 31 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 36 40
M  V30 39 1 37 41
M  V30 40 1 38 42
M  V30 41 1 39 43
M  V30 42 1 43 44
M  V30 43 1 44 45
M  V30 44 1 44 46
M  V30 45 1 45 47
M  V30 46 1 46 48
M  V30 47 1 47 49
M  V30 48 1 48 50
M  V30 49 1 50 51
M  V30 50 1 51 52
M  V30 51 1 51 53
M  V30 52 1 51 54
M  V30 53 1 52 55
M  V30 54 1 53 56
M  V30 55 1 54 57
M  V30 56 1 55 58
M  V30 57 1 56 59
M  V30 58 1 57 60
M  V30 59 1 61 62
M  V30 60 1 61 63
M  V30 61 1 61 64
M  V30 62 1 61 65
M  V30 63 1 62 66
M  V30 64 1 63 67
M  V30 65 1 64 68
M  V30 66 1 65 69
M  V30 67 1 66 70
M  V30 68 1 67 71
M  V30 69 1 68 72
M  V30 70 1 69 73
M  V30 71 1 73 74
M  V30 72 1 74 75
M  V30 73 1 74 76
M  V30 74 1 75 77
M  V30 75 1 76 78
M  V30 76 1 77 79
M  V30 77 1 78 80
M  V30 78 1 79 81
M  V30 79 1 80 82
M  V30 80 1 81 83
M  V30 81 1 81 84
M  V30 82 1 81 85
M  V30 83 1 82 86
M  V30 84 1 82 87
M  V30 85 1 82 88
M  V30 86 1 83 89
M  V30 87 1 84 90
M  V30 88 1 85 91
M  V30 89 1 86 92
M  V30 90 1 87 93
M  V30 91 1 88 94
M  V30 92 1 89 95
M  V30 93 1 90 96
M  V30 94 1 91 97
M  V30 95 1 92 98
M  V30 96 1 93 99
M  V30 97 1 94 100
M  V30 98 1 101 102
M  V30 99 1 101 103
M  V30 100 1 101 104
M  V30 101 1 101 105
M  V30 102 1 102 106
M  V30 103 1 103 107
M  V30 104 1 104 108
M  V30 105 1 105 109
M  V30 106 1 109 110
M  V30 107 1 110 111
M  V30 108 1 111 112
M  V30 109 1 111 113
M  V30 110 1 112 114
M  V30 111 1 113 115
M  V30 112 2 114 116
M  V30 113 1 115 117
M  V30 114 1 117 118
M  V30 115 1 118 119
M  V30 116 1 118 120
M  V30 117 1 118 121
M  V30 118 1 119 122
M  V30 119 1 120 123
M  V30 120 1 121 124
M  V30 121 1 125 126
M  V30 122 1 125 127
M  V30 123 1 125 128
M  V30 124 1 125 129
M  V30 125 1 126 130
M  V30 126 1 127 131
M  V30 127 1 128 132
M  V30 128 1 129 133
M  V30 129 1 133 134
M  V30 130 1 134 135
M  V30 131 1 135 136
M  V30 132 1 135 137
M  V30 133 1 136 138
M  V30 134 1 137 139
M  V30 135 1 138 140
M  V30 136 1 139 141
M  V30 137 1 141 142
M  V30 138 1 142 143
M  V30 139 1 142 144
M  V30 140 1 142 145
M  V30 141 1 143 146
M  V30 142 1 144 147
M  V30 143 1 145 148
M  V30 144 1 149 150
M  V30 145 1 149 151
M  V30 146 1 149 152
M  V30 147 1 149 153
M  V30 148 1 150 154
M  V30 149 1 151 155
M  V30 150 1 152 156
M  V30 151 1 153 157
M  V30 152 1 157 158
M  V30 153 1 158 159
M  V30 154 1 159 160
M  V30 155 1 159 161
M  V30 156 1 160 162
M  V30 157 1 161 163
M  V30 158 1 162 164
M  V30 159 1 163 165
M  V30 160 1 164 166
M  V30 161 1 165 167
M  V30 162 1 166 168
M  V30 163 1 166 169
M  V30 164 1 166 170
M  V30 165 1 167 171
M  V30 166 1 167 172
M  V30 167 1 167 173
M  V30 168 1 168 174
M  V30 169 1 169 175
M  V30 170 1 170 176
M  V30 171 1 171 177
M  V30 172 1 172 178
M  V30 173 1 173 179
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025002.cdx

>  <name>
US20220000751A1-20220106-C00004

>  <Row No>
711

$$$$
US20220000751A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 143 133 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.2091 -0.8637 0.0 0
M  V30 3 O 1.094 -0.5758 0.0 0
M  V30 4 O 0.8637 1.2091 0.0 0
M  V30 5 C -1.4395 0.9212 0.0 0
M  V30 6 C -0.3454 -1.7274 0.0 0
M  V30 7 C 2.188 0.3454 0.0 0
M  V30 8 C -0.3454 2.4183 0.0 0
M  V30 9 C -2.879 0.3454 0.0 0
M  V30 10 C 0.9212 -1.1516 0.0 0
M  V30 11 C 3.282 -0.2303 0.0 0
M  V30 12 C 0.2303 3.8578 0.0 0
M  V30 13 C -4.3185 1.2667 0.0 0
M  V30 14 C -5.758 0.6909 0.0 0
M  V30 15 C -7.1975 1.6122 0.0 0
M  V30 16 C -8.637 1.0364 0.0 0
M  V30 17 C -10.0765 1.9577 0.0 0
M  V30 18 C -11.516 1.3819 0.0 0
M  V30 19 C -12.9556 2.3032 0.0 0
M  V30 20 C -14.3951 1.7274 0.0 0
M  V30 21 C -15.8346 2.6487 0.0 0
M  V30 22 C -17.2741 2.0728 0.0 0
M  V30 23 Si -5.067 16.5831 0.0 0
M  V30 24 O -4.2033 17.7923 0.0 0
M  V30 25 O -3.973 16.0073 0.0 0
M  V30 26 O -6.2762 15.7194 0.0 0
M  V30 27 C -6.5065 17.5044 0.0 0
M  V30 28 C -5.4125 19.0015 0.0 0
M  V30 29 C -2.879 16.9286 0.0 0
M  V30 30 C -5.4125 14.8557 0.0 0
M  V30 31 C -7.9461 16.9286 0.0 0
M  V30 32 C -4.5488 20.2107 0.0 0
M  V30 33 C -1.7849 16.3528 0.0 0
M  V30 34 C -4.1457 15.4315 0.0 0
M  V30 35 C -9.3856 17.8499 0.0 0
M  V30 36 C -10.8251 17.2741 0.0 0
M  V30 37 C -12.2646 18.1954 0.0 0
M  V30 38 C -13.7041 17.6196 0.0 0
M  V30 39 C -15.1436 18.5409 0.0 0
M  V30 40 C -16.5831 17.9651 0.0 0
M  V30 41 Si -7.3702 32.7057 0.0 0
M  V30 42 O -6.5065 33.9148 0.0 0
M  V30 43 O -6.2762 32.1298 0.0 0
M  V30 44 O -8.5794 31.8419 0.0 0
M  V30 45 C -8.8098 33.6269 0.0 0
M  V30 46 C -7.7157 35.124 0.0 0
M  V30 47 C -5.1822 33.0511 0.0 0
M  V30 48 C -7.7157 30.9782 0.0 0
M  V30 49 C -10.2493 33.0511 0.0 0
M  V30 50 C -6.852 36.3332 0.0 0
M  V30 51 C -4.0882 32.4753 0.0 0
M  V30 52 C -6.449 31.554 0.0 0
M  V30 53 C -11.6888 33.9724 0.0 0
M  V30 54 C -13.1283 33.3966 0.0 0
M  V30 55 C -14.5678 34.3179 0.0 0
M  V30 56 C -16.0073 33.7421 0.0 0
M  V30 57 Si -2.3032 9.6735 0.0 0
M  V30 58 O -1.497 10.8251 0.0 0
M  V30 59 O -3.4548 8.8673 0.0 0
M  V30 60 O -1.2667 9.1552 0.0 0
M  V30 61 C -3.6851 10.5372 0.0 0
M  V30 62 C -2.6487 11.9767 0.0 0
M  V30 63 C -2.6487 8.0612 0.0 0
M  V30 64 C -0.2303 10.019 0.0 0
M  V30 65 C -5.067 10.019 0.0 0
M  V30 66 C -6.449 10.8827 0.0 0
M  V30 67 C -7.8309 10.3644 0.0 0
M  V30 68 C -9.2128 11.2281 0.0 0
M  V30 69 C -10.5948 10.7099 0.0 0
M  V30 70 C -11.9767 11.5736 0.0 0
M  V30 71 C -13.3586 11.0554 0.0 0
M  V30 72 C -14.7405 11.9191 0.0 0
M  V30 73 C -16.1225 11.4009 0.0 0
M  V30 74 C -17.5044 12.2646 0.0 0
M  V30 75 C -18.8863 11.7464 0.0 0
M  V30 76 Si -5.067 25.3354 0.0 0
M  V30 77 O -4.2033 26.5445 0.0 0
M  V30 78 O -6.2762 24.4716 0.0 0
M  V30 79 O -3.973 24.7596 0.0 0
M  V30 80 C -6.5065 26.2566 0.0 0
M  V30 81 C -5.4125 27.7537 0.0 0
M  V30 82 C -5.4125 23.6079 0.0 0
M  V30 83 C -2.879 25.6808 0.0 0
M  V30 84 C -7.9461 25.6808 0.0 0
M  V30 85 C -9.3856 26.6021 0.0 0
M  V30 86 C -10.8251 26.0263 0.0 0
M  V30 87 C -12.2646 26.9476 0.0 0
M  V30 88 C -13.7041 26.3718 0.0 0
M  V30 89 C -15.1436 27.2931 0.0 0
M  V30 90 C -16.5831 26.7173 0.0 0
M  V30 91 Si -7.3702 41.4579 0.0 0
M  V30 92 O -6.5065 42.6671 0.0 0
M  V30 93 O -8.5794 40.5942 0.0 0
M  V30 94 O -6.2762 40.8821 0.0 0
M  V30 95 C -8.8098 42.3792 0.0 0
M  V30 96 C -7.7157 43.8763 0.0 0
M  V30 97 C -7.7157 39.7305 0.0 0
M  V30 98 C -5.1822 41.8034 0.0 0
M  V30 99 C -10.2493 41.8034 0.0 0
M  V30 100 C -11.6888 42.7247 0.0 0
M  V30 101 C -13.1283 42.1489 0.0 0
M  V30 102 C -14.5678 43.0701 0.0 0
M  V30 103 C -16.0073 42.4943 0.0 0
M  V30 104 Si -5.5277 49.7495 0.0 0
M  V30 105 O -6.7369 48.8858 0.0 0
M  V30 106 O -4.4336 49.1737 0.0 0
M  V30 107 O -4.664 50.9587 0.0 0
M  V30 108 C -6.9672 50.6708 0.0 0
M  V30 109 C -5.8732 48.0221 0.0 0
M  V30 110 C -3.3396 50.095 0.0 0
M  V30 111 C -5.8732 52.1679 0.0 0
M  V30 112 C -8.4067 50.095 0.0 0
M  V30 113 C -4.5488 48.1948 0.0 0
M  V30 114 C -2.2456 49.5192 0.0 0
M  V30 115 C -5.0095 53.377 0.0 0
M  V30 116 Si -12.4373 50.2101 0.0 0
M  V30 117 O -11.5736 51.4193 0.0 0
M  V30 118 O -13.6465 49.3464 0.0 0
M  V30 119 O -11.3433 49.6343 0.0 0
M  V30 120 C -13.8768 51.1314 0.0 0
M  V30 121 C -12.7828 52.6285 0.0 0
M  V30 122 C -12.7828 48.4827 0.0 0
M  V30 123 C -10.2493 50.5556 0.0 0
M  V30 124 C -15.3164 50.5556 0.0 0
M  V30 125 Si -5.9883 58.5017 0.0 0
M  V30 126 O -7.1975 57.638 0.0 0
M  V30 127 O -4.8943 57.9259 0.0 0
M  V30 128 O -5.1246 59.7109 0.0 0
M  V30 129 C -7.4278 59.423 0.0 0
M  V30 130 C -6.3338 56.7743 0.0 0
M  V30 131 C -3.8003 58.8472 0.0 0
M  V30 132 C -6.3338 60.9201 0.0 0
M  V30 133 C -5.0095 56.947 0.0 0
M  V30 134 C -2.7062 58.2714 0.0 0
M  V30 135 C -5.4701 62.1293 0.0 0
M  V30 136 Si -12.898 58.9623 0.0 0
M  V30 137 O -12.0343 60.1715 0.0 0
M  V30 138 O -14.1072 58.0986 0.0 0
M  V30 139 O -11.8039 58.3865 0.0 0
M  V30 140 C -14.3375 59.8836 0.0 0
M  V30 141 C -13.2435 61.3807 0.0 0
M  V30 142 C -13.2435 57.2349 0.0 0
M  V30 143 C -10.7099 59.3078 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 23 24
M  V30 23 1 23 25
M  V30 24 1 23 26
M  V30 25 1 23 27
M  V30 26 1 24 28
M  V30 27 1 25 29
M  V30 28 1 26 30
M  V30 29 1 27 31
M  V30 30 1 28 32
M  V30 31 1 29 33
M  V30 32 1 30 34
M  V30 33 1 31 35
M  V30 34 1 35 36
M  V30 35 1 36 37
M  V30 36 1 37 38
M  V30 37 1 38 39
M  V30 38 1 39 40
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 41 44
M  V30 42 1 41 45
M  V30 43 1 42 46
M  V30 44 1 43 47
M  V30 45 1 44 48
M  V30 46 1 45 49
M  V30 47 1 46 50
M  V30 48 1 47 51
M  V30 49 1 48 52
M  V30 50 1 49 53
M  V30 51 1 53 54
M  V30 52 1 54 55
M  V30 53 1 55 56
M  V30 54 1 57 58
M  V30 55 1 57 59
M  V30 56 1 57 60
M  V30 57 1 57 61
M  V30 58 1 58 62
M  V30 59 1 59 63
M  V30 60 1 60 64
M  V30 61 1 61 65
M  V30 62 1 65 66
M  V30 63 1 66 67
M  V30 64 1 67 68
M  V30 65 1 68 69
M  V30 66 1 69 70
M  V30 67 1 70 71
M  V30 68 1 71 72
M  V30 69 1 72 73
M  V30 70 1 73 74
M  V30 71 1 74 75
M  V30 72 1 76 77
M  V30 73 1 76 78
M  V30 74 1 76 79
M  V30 75 1 76 80
M  V30 76 1 77 81
M  V30 77 1 78 82
M  V30 78 1 79 83
M  V30 79 1 80 84
M  V30 80 1 84 85
M  V30 81 1 85 86
M  V30 82 1 86 87
M  V30 83 1 87 88
M  V30 84 1 88 89
M  V30 85 1 89 90
M  V30 86 1 91 92
M  V30 87 1 91 93
M  V30 88 1 91 94
M  V30 89 1 91 95
M  V30 90 1 92 96
M  V30 91 1 93 97
M  V30 92 1 94 98
M  V30 93 1 95 99
M  V30 94 1 99 100
M  V30 95 1 100 101
M  V30 96 1 101 102
M  V30 97 1 102 103
M  V30 98 1 104 105
M  V30 99 1 104 106
M  V30 100 1 104 107
M  V30 101 1 104 108
M  V30 102 1 105 109
M  V30 103 1 106 110
M  V30 104 1 107 111
M  V30 105 1 108 112
M  V30 106 1 109 113
M  V30 107 1 110 114
M  V30 108 1 111 115
M  V30 109 1 116 117
M  V30 110 1 116 118
M  V30 111 1 116 119
M  V30 112 1 116 120
M  V30 113 1 117 121
M  V30 114 1 118 122
M  V30 115 1 119 123
M  V30 116 1 120 124
M  V30 117 1 125 126
M  V30 118 1 125 127
M  V30 119 1 125 128
M  V30 120 1 125 129
M  V30 121 1 126 130
M  V30 122 1 127 131
M  V30 123 1 128 132
M  V30 124 1 130 133
M  V30 125 1 131 134
M  V30 126 1 132 135
M  V30 127 1 136 137
M  V30 128 1 136 138
M  V30 129 1 136 139
M  V30 130 1 136 140
M  V30 131 1 137 141
M  V30 132 1 138 142
M  V30 133 1 139 143
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000751A1-20220106-C00005

>  <Row No>
712

$$$$
US20220000751A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.6891 0.0402 0.0 0
M  V30 3 O 0.2144 -1.4344 0.0 0
M  V30 4 O 0.2144 1.5148 0.0 0
M  V30 5 C -1.3137 -0.6836 0.0 0
M  V30 6 C 2.3728 1.3539 0.0 0
M  V30 7 C 1.555 -1.8767 0.0 0
M  V30 8 C -0.9518 2.5068 0.0 0
M  V30 9 C -2.6275 0.0804 0.0 0
M  V30 10 C 3.8072 1.3941 0.0 0
M  V30 11 C 1.7695 -3.2843 0.0 0
M  V30 12 C -0.7373 3.9948 0.0 0
M  V30 13 C -3.9412 -0.6032 0.0 0
M  V30 14 N -5.255 0.1608 0.0 0
M  V30 15 Si 6.9709 -4.5043 0.0 0
M  V30 16 O 7.1854 -5.9387 0.0 0
M  V30 17 O 7.1854 -2.9894 0.0 0
M  V30 18 O 8.66 -4.464 0.0 0
M  V30 19 C 5.6571 -5.1879 0.0 0
M  V30 20 C 8.526 -6.381 0.0 0
M  V30 21 C 6.0191 -1.9974 0.0 0
M  V30 22 C 4.3434 -4.4238 0.0 0
M  V30 23 C 8.7404 -7.7886 0.0 0
M  V30 24 C 6.2336 -0.5094 0.0 0
M  V30 25 C 3.0296 -5.1075 0.0 0
M  V30 26 N 1.7159 -4.3434 0.0 0
M  V30 27 O -0.3217 10.6172 0.0 0
M  V30 28 C -1.6354 11.3814 0.0 0
M  V30 29 C -2.9492 10.6977 0.0 0
M  V30 30 O 4.826 0.3217 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 15 16
M  V30 15 1 15 17
M  V30 16 1 15 18
M  V30 17 1 15 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 19 22
M  V30 21 1 20 23
M  V30 22 1 21 24
M  V30 23 1 22 25
M  V30 24 1 25 26
M  V30 25 1 27 28
M  V30 26 1 28 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000751A1-20220106-C00006

>  <Row No>
713

$$$$
US20220000751A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 46 42 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.4444 0.0424 0.0 0
M  V30 3 O -0.0424 1.5294 0.0 0
M  V30 4 O -0.0424 -1.4444 0.0 0
M  V30 5 C -1.3311 -0.7222 0.0 0
M  V30 6 C 2.1666 1.3736 0.0 0
M  V30 7 C -1.3736 2.3366 0.0 0
M  V30 8 C 1.2037 -2.1666 0.0 0
M  V30 9 C -2.6623 0.0849 0.0 0
M  V30 10 C 3.6111 1.4161 0.0 0
M  V30 11 C -1.4161 3.866 0.0 0
M  V30 12 C 1.1612 -3.6111 0.0 0
M  V30 13 C -3.9935 -0.6372 0.0 0
M  V30 14 N -5.3246 0.1699 0.0 0
M  V30 15 Si -0.3398 14.5012 0.0 0
M  V30 16 O 1.1045 14.5437 0.0 0
M  V30 17 O -0.3823 16.0307 0.0 0
M  V30 18 O -0.3823 13.0568 0.0 0
M  V30 19 C -1.671 13.779 0.0 0
M  V30 20 C 1.8268 15.8749 0.0 0
M  V30 21 C -1.7135 16.8379 0.0 0
M  V30 22 C 0.8638 12.3345 0.0 0
M  V30 23 C -3.0022 14.5862 0.0 0
M  V30 24 C 3.2712 15.9174 0.0 0
M  V30 25 C -1.756 18.3673 0.0 0
M  V30 26 C 0.8213 10.8901 0.0 0
M  V30 27 C -4.3333 13.864 0.0 0
M  V30 28 N -5.6645 14.6712 0.0 0
M  V30 29 Si 6.0044 8.4968 0.0 0
M  V30 30 O 5.9619 7.0523 0.0 0
M  V30 31 O 7.4488 8.5393 0.0 0
M  V30 32 O 5.9619 10.0262 0.0 0
M  V30 33 C 4.6732 7.7746 0.0 0
M  V30 34 C 7.2081 6.3301 0.0 0
M  V30 35 C 3.342 8.5818 0.0 0
M  V30 36 C 7.1656 4.8856 0.0 0
M  V30 37 C 2.0109 7.8595 0.0 0
M  V30 38 N 0.6797 8.6667 0.0 0
M  V30 39 Si 7.1373 -5.6645 0.0 0
M  V30 40 O 8.5818 -5.622 0.0 0
M  V30 41 O 7.0948 -4.1351 0.0 0
M  V30 42 O 7.0948 -7.109 0.0 0
M  V30 43 C 5.8061 -6.3867 0.0 0
M  V30 44 C 4.475 -5.5795 0.0 0
M  V30 45 C 3.1438 -6.3018 0.0 0
M  V30 46 N 1.8126 -5.4946 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 13 14
M  V30 14 1 15 16
M  V30 15 1 15 17
M  V30 16 1 15 18
M  V30 17 1 15 19
M  V30 18 1 16 20
M  V30 19 1 17 21
M  V30 20 1 18 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 23 27
M  V30 26 1 27 28
M  V30 27 1 29 30
M  V30 28 1 29 31
M  V30 29 1 29 32
M  V30 30 1 29 33
M  V30 31 1 30 34
M  V30 32 1 33 35
M  V30 33 1 34 36
M  V30 34 1 35 37
M  V30 35 1 37 38
M  V30 36 1 39 40
M  V30 37 1 39 41
M  V30 38 1 39 42
M  V30 39 1 39 43
M  V30 40 1 43 44
M  V30 41 1 44 45
M  V30 42 1 45 46
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000751A1-20220106-C00007

>  <Row No>
714

$$$$
US20220000751A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 73 65 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.5193 0.0406 0.0 0
M  V30 3 O 1.6956 0.0406 0.0 0
M  V30 4 O -0.0406 1.5193 0.0 0
M  V30 5 C -0.0406 -1.4379 0.0 0
M  V30 6 Si -3.0386 0.0813 0.0 0
M  V30 7 C 2.3875 1.3565 0.0 0
M  V30 8 C 1.1937 -2.1297 0.0 0
M  V30 9 O -3.0793 1.6007 0.0 0
M  V30 10 C -3.0793 -1.3565 0.0 0
M  V30 11 C -4.5579 0.122 0.0 0
M  V30 12 C 3.8254 1.3972 0.0 0
M  V30 13 C 1.153 -3.5677 0.0 0
M  V30 14 C -4.3952 2.3739 0.0 0
M  V30 15 C -1.8449 -2.0483 0.0 0
M  V30 16 N 2.1569 -4.5715 0.0 0
M  V30 17 C -4.4359 3.8932 0.0 0
M  V30 18 C -1.8856 -3.4863 0.0 0
M  V30 19 N -0.8817 -4.4901 0.0 0
M  V30 20 Si -2.9301 4.8835 0.0 0
M  V30 21 O -1.2344 4.9242 0.0 0
M  V30 22 O -2.713 3.4456 0.0 0
M  V30 23 O -2.713 6.4029 0.0 0
M  V30 24 C -4.2459 4.1917 0.0 0
M  V30 25 C -0.5426 6.2401 0.0 0
M  V30 26 C -1.3701 2.9979 0.0 0
M  V30 27 C -5.5618 4.9649 0.0 0
M  V30 28 C 0.8953 6.2808 0.0 0
M  V30 29 C -1.153 1.5871 0.0 0
M  V30 30 C -6.8776 4.2731 0.0 0
M  V30 31 N -8.1935 5.0463 0.0 0
M  V30 32 Si -7.054 9.7671 0.0 0
M  V30 33 O -5.3583 9.8078 0.0 0
M  V30 34 O -6.8369 8.3292 0.0 0
M  V30 35 O -6.8369 11.2864 0.0 0
M  V30 36 C -8.3698 9.0753 0.0 0
M  V30 37 C -4.6665 11.1236 0.0 0
M  V30 38 C -5.494 7.8815 0.0 0
M  V30 39 C -9.6857 9.8485 0.0 0
M  V30 40 C -3.2285 11.1643 0.0 0
M  V30 41 C -5.2769 6.4707 0.0 0
M  V30 42 C -11.0015 9.1566 0.0 0
M  V30 43 N -12.3174 9.9299 0.0 0
M  V30 44 Si -0.217 -12.2631 0.0 0
M  V30 45 O -1.7363 -12.2224 0.0 0
M  V30 46 O 1.3972 -12.2224 0.0 0
M  V30 47 O -0.2577 -10.7438 0.0 0
M  V30 48 C -0.2577 -13.7011 0.0 0
M  V30 49 Si -3.2557 -12.1817 0.0 0
M  V30 50 C 2.089 -10.9066 0.0 0
M  V30 51 O -3.2964 -10.6624 0.0 0
M  V30 52 C -3.2964 -13.6197 0.0 0
M  V30 53 C -4.775 -12.141 0.0 0
M  V30 54 C -4.6122 -9.8892 0.0 0
M  V30 55 Si -10.8523 -7.7051 0.0 0
M  V30 56 O -9.1566 -7.6644 0.0 0
M  V30 57 O -10.6353 -9.1431 0.0 0
M  V30 58 O -10.6353 -6.1858 0.0 0
M  V30 59 C -12.3717 -7.6644 0.0 0
M  V30 60 C -8.4648 -6.3486 0.0 0
M  V30 61 C -9.2923 -9.5907 0.0 0
M  V30 62 Si -3.3642 -7.7051 0.0 0
M  V30 63 O -1.6685 -7.6644 0.0 0
M  V30 64 O -3.1471 -9.1431 0.0 0
M  V30 65 O -3.1471 -6.1858 0.0 0
M  V30 66 C -4.8835 -7.6644 0.0 0
M  V30 67 C -0.9767 -6.3486 0.0 0
M  V30 68 C -1.8042 -9.5907 0.0 0
M  V30 69 O -7.054 13.891 0.0 0
M  V30 70 C -8.3698 14.6642 0.0 0
M  V30 71 C -9.6857 13.9724 0.0 0
M  V30 72 O -6.0773 4.2324 0.0 0
M  V30 73 C -7.5966 4.2731 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 8 13
M  V30 13 1 9 14
M  V30 14 1 10 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 18 19
M  V30 19 1 20 21
M  V30 20 1 20 22
M  V30 21 1 20 23
M  V30 22 1 20 24
M  V30 23 1 21 25
M  V30 24 1 22 26
M  V30 25 1 24 27
M  V30 26 1 25 28
M  V30 27 1 26 29
M  V30 28 1 27 30
M  V30 29 1 30 31
M  V30 30 1 32 33
M  V30 31 1 32 34
M  V30 32 1 32 35
M  V30 33 1 32 36
M  V30 34 1 33 37
M  V30 35 1 34 38
M  V30 36 1 36 39
M  V30 37 1 37 40
M  V30 38 1 38 41
M  V30 39 1 39 42
M  V30 40 1 42 43
M  V30 41 1 44 45
M  V30 42 1 44 46
M  V30 43 1 44 47
M  V30 44 1 44 48
M  V30 45 1 45 49
M  V30 46 1 46 50
M  V30 47 1 49 51
M  V30 48 1 49 52
M  V30 49 1 49 53
M  V30 50 1 51 54
M  V30 51 1 55 56
M  V30 52 1 55 57
M  V30 53 1 55 58
M  V30 54 1 55 59
M  V30 55 1 56 60
M  V30 56 1 57 61
M  V30 57 1 62 63
M  V30 58 1 62 64
M  V30 59 1 62 65
M  V30 60 1 62 66
M  V30 61 1 63 67
M  V30 62 1 64 68
M  V30 63 1 69 70
M  V30 64 1 70 71
M  V30 65 1 72 73
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000751A1-20220106-C00008

>  <Row No>
715

$$$$
US20220000751A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.4724 0.0362 0.0 0
M  V30 3 C -1.5448 0.0362 0.0 0
M  V30 4 C -0.0362 1.5448 0.0 0
M  V30 5 C -0.0362 -1.4724 0.0 0
M  V30 6 Si 2.9448 0.0724 0.0 0
M  V30 7 C 2.9086 1.6172 0.0 0
M  V30 8 C 2.9086 -1.3999 0.0 0
M  V30 9 C 4.4172 0.1086 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 6 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000751A1-20220106-C00009

>  <Row No>
716

$$$$
US20220000751A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -1.5355 0.0359 0.0 0
M  V30 3 O 1.4635 0.0359 0.0 0
M  V30 4 C -0.0359 1.5355 0.0 0
M  V30 5 C -0.0359 -1.4635 0.0 0
M  V30 6 Si -3.0711 0.0719 0.0 0
M  V30 7 Si 2.9271 0.0719 0.0 0
M  V30 8 C -4.6066 0.1079 0.0 0
M  V30 9 C -3.1071 1.6075 0.0 0
M  V30 10 C -3.1071 -1.3915 0.0 0
M  V30 11 C 2.8911 1.6075 0.0 0
M  V30 12 C 2.8911 -1.3915 0.0 0
M  V30 13 C 4.3907 0.1079 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 1 7 13
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000751A1-20220106-C00010

>  <Row No>
717

$$$$
US20220000751A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 17 16 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O 1.4679 0.036 0.0 0
M  V30 3 O -1.5401 0.036 0.0 0
M  V30 4 C -0.036 1.5401 0.0 0
M  V30 5 C -0.036 -1.4679 0.0 0
M  V30 6 Si 2.9359 0.0721 0.0 0
M  V30 7 Si -3.0803 0.0721 0.0 0
M  V30 8 O 4.4039 0.1082 0.0 0
M  V30 9 C 2.8998 1.6123 0.0 0
M  V30 10 C 2.8998 -1.3957 0.0 0
M  V30 11 C -4.6205 0.1082 0.0 0
M  V30 12 C -3.1164 1.6123 0.0 0
M  V30 13 C -3.1164 -1.3957 0.0 0
M  V30 14 Si 5.8719 0.1443 0.0 0
M  V30 15 C 5.8358 1.6845 0.0 0
M  V30 16 C 5.8358 -1.3235 0.0 0
M  V30 17 C 7.3398 0.1804 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 1 7 13
M  V30 13 1 8 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000751A1-20220106-C00011

>  <Row No>
718

$$$$
US20220000752A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.4504 -0.4279 0.0 0
M  V30 3 O -2.6868 0.4755 0.0 0
M  V30 4 C -1.9497 -1.807 0.0 0
M  V30 5 C -3.9233 -0.3566 0.0 0 CFG=2
M  V30 6 O -1.1175 -2.9721 0.0 0
M  V30 7 C -3.4715 -1.7714 0.0 0
M  V30 8 C -5.3975 0.0713 0.0 0 CFG=2
M  V30 9 O -4.375 -2.9365 0.0 0
M  V30 10 O -5.8255 1.5455 0.0 0
M  V30 11 C -6.4793 -0.9392 0.0 0
M  V30 12 O -7.9536 -0.5112 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=3
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 8 10 CFG=1
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 1 5 7
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 5 8)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000752A1-20220106-C00001

>  <Row No>
719

$$$$
US20220000752A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000752A1-20220106-C00002

>  <Row No>
720

$$$$
US20220000752A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 7 6 0 0 0
M  V30 BEGIN ATOM
M  V30 1 P 0.0 0.0 0.0 0 CFG=2
M  V30 2 O 0.3593 1.4838 0.0 0
M  V30 3 O -0.4289 -1.4143 0.0 0
M  V30 4 O 1.4143 -0.3593 0.0 0 CHG=-1
M  V30 5 C -1.4838 0.4057 0.0 0
M  V30 6 C 0.9853 -1.7737 0.0 0
M  V30 7 C -2.9677 0.8115 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5 CFG=3
M  V30 5 1 3 6
M  V30 6 1 5 7
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 1)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000752A1-20220106-C00003

>  <Row No>
721

$$$$
US20220000752A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.2968 -0.6799 0.0 0
M  V30 3 C 1.5864 -0.768 0.0 0
M  V30 4 C -2.5937 0.0755 0.0 0
M  V30 5 C 2.8077 -0.0125 0.0 0
M  V30 6 O -3.8905 -0.6043 0.0 0
M  V30 7 O 3.8024 -1.0072 0.0 0
M  V30 8 C -5.1874 0.151 0.0 0
M  V30 9 C -6.4842 -0.5288 0.0 0
M  V30 10 C -7.7937 0.2014 0.0 0
M  V30 11 C -9.0905 0.9569 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000752A1-20220106-C00004

>  <Row No>
722

$$$$
US20220000752A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 5 4 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Y 0.0 0.0 0.0 0 VAL=1
M  V30 2 C -1.3096 0.7551 0.0 0
M  V30 3 O -1.345 2.2653 0.0 0
M  V30 4 C -2.6193 0.0471 0.0 0
M  V30 5 C -3.929 -0.6607 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 4 5
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000752A1-20220106-C00005

>  <Row No>
723

$$$$
US20220000752A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.2968 -0.6799 0.0 0
M  V30 3 C 1.5864 -0.768 0.0 0
M  V30 4 C -2.5937 0.0755 0.0 0
M  V30 5 C 2.8077 -0.0125 0.0 0
M  V30 6 O -3.8905 -0.6043 0.0 0
M  V30 7 O 3.8024 -1.0072 0.0 0
M  V30 8 C -5.1874 0.151 0.0 0
M  V30 9 C -6.4842 -0.5288 0.0 0
M  V30 10 C -7.7937 0.2014 0.0 0
M  V30 11 C -9.0905 0.9569 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000752A1-20220106-C00006

>  <Row No>
724

$$$$
US20220000752A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 6 5 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.3574 1.4758 0.0 0
M  V30 3 O -0.4266 -1.4066 0.0 0
M  V30 4 C -1.4758 0.4035 0.0 0
M  V30 5 C 1.4066 -0.3574 0.0 0
M  V30 6 C -2.9517 0.8071 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000752A1-20220106-C00007

>  <Row No>
725

$$$$
US20220000752A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 6 5 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.0358 1.5282 0.0 0
M  V30 3 O -0.0358 -1.4565 0.0 0
M  V30 4 C -1.5282 0.0358 0.0 0
M  V30 5 C 1.4565 0.0358 0.0 0
M  V30 6 C -3.0564 0.0716 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000752A1-20220106-C00008

>  <Row No>
726

$$$$
US20220000752A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.2968 -0.6799 0.0 0
M  V30 3 C 1.5864 -0.768 0.0 0
M  V30 4 C -2.5937 0.0755 0.0 0
M  V30 5 C 2.8077 -0.0125 0.0 0
M  V30 6 O -3.8905 -0.6043 0.0 0
M  V30 7 O 3.8024 -1.0072 0.0 0
M  V30 8 C -5.1874 0.151 0.0 0
M  V30 9 C -6.4842 -0.5288 0.0 0
M  V30 10 C -7.7937 0.2014 0.0 0
M  V30 11 C -9.0905 0.9569 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000752A1-20220106-C00009

>  <Row No>
727

$$$$
US20220000752A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 6 5 0 0 0
M  V30 BEGIN ATOM
M  V30 1 U 0.0 0.0 0.0 0 VAL=1
M  V30 2 O -1.3116 -0.7089 0.0 0
M  V30 3 C -2.6232 0.0472 0.0 0
M  V30 4 O -2.6587 1.5597 0.0 0
M  V30 5 C -3.9349 -0.6617 0.0 0
M  V30 6 C -5.2465 -1.3707 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 2 3 4
M  V30 4 1 3 5
M  V30 5 1 5 6
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000752A1-20220106-C00010

>  <Row No>
728

$$$$
US20220000752A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.2968 -0.6799 0.0 0
M  V30 3 C 1.5864 -0.768 0.0 0
M  V30 4 C -2.5937 0.0755 0.0 0
M  V30 5 C 2.8077 -0.0125 0.0 0
M  V30 6 O -3.8905 -0.6043 0.0 0
M  V30 7 O 3.8024 -1.0072 0.0 0
M  V30 8 C -5.1874 0.151 0.0 0
M  V30 9 C -6.4842 -0.5288 0.0 0
M  V30 10 C -7.7937 0.2014 0.0 0
M  V30 11 C -9.0905 0.9569 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000752A1-20220106-C00011

>  <Row No>
729

$$$$
US20220000752A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 7 6 0 0 0
M  V30 BEGIN ATOM
M  V30 1 W 0.0 0.0 0.0 0 VAL=1
M  V30 2 C 0.3619 -1.4242 0.0 0 CFG=2
M  V30 3 O 1.0857 -2.6967 0.0 0
M  V30 4 C -1.1324 -1.7861 0.0 0
M  V30 5 C 1.3892 -0.3268 0.0 0
M  V30 6 C 2.5099 -2.2648 0.0 0
M  V30 7 C -2.6267 -2.148 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=3
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000752A1-20220106-C00012

>  <Row No>
730

$$$$
US20220000752A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 13 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.4848 0.0365 0.0 0
M  V30 3 C -0.7789 -1.2779 0.0 0
M  V30 4 O 2.2151 1.3875 0.0 0
M  V30 5 C 2.2151 -1.2414 0.0 0
M  V30 6 C -0.0486 -2.5559 0.0 0
M  V30 7 C -2.3368 -1.2414 0.0 0
M  V30 8 C 3.7 1.424 0.0 0
M  V30 9 O 3.7 -1.2049 0.0 0
M  V30 10 C 1.424 -2.5194 0.0 0
M  V30 11 O -0.8398 -3.8339 0.0 0
M  V30 12 C -3.8947 -1.2049 0.0 0
M  V30 13 O 2.1542 -3.7974 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 10 13
M  V30 13 1 6 10
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000752A1-20220106-C00013

>  <Row No>
731

$$$$
US20220000752A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 51 53 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.4099 -0.3896 0.0 0
M  V30 3 O -2.6158 0.5194 0.0 0
M  V30 4 C -1.9109 -1.6882 0.0 0
M  V30 5 C -3.8218 -0.2782 0.0 0 CFG=1
M  V30 6 O -1.1131 -2.8199 0.0 0
M  V30 7 C -3.395 -1.6326 0.0 0
M  V30 8 C -5.2503 0.1484 0.0 0 CFG=1
M  V30 9 C -2.7457 -3.6919 0.0 0
M  V30 10 O -4.3041 -2.7643 0.0 0
M  V30 11 O -5.677 1.5769 0.0 0
M  V30 12 C -6.3449 -0.8348 0.0 0
M  V30 13 C -6.3449 -0.8348 0.0 0
M  V30 14 C -3.8403 -4.6752 0.0 0
M  V30 15 C -2.0778 -4.8607 0.0 0
M  V30 16 C -7.1612 1.6326 0.0 0
M  V30 17 O -7.6621 -0.1113 0.0 0
M  V30 18 C -8.6454 1.6882 0.0 0
M  V30 19 C -7.5879 3.0611 0.0 0
M  V30 20 O -2.2262 18.9976 0.0 0
M  V30 21 C -3.6362 18.608 0.0 0
M  V30 22 O -4.8421 19.5171 0.0 0
M  V30 23 C -4.1371 17.3094 0.0 0
M  V30 24 C -6.048 18.7194 0.0 0 CFG=1
M  V30 25 O -3.3394 16.1777 0.0 0
M  V30 26 C -5.6213 17.365 0.0 0
M  V30 27 C -7.4766 19.1461 0.0 0 CFG=1
M  V30 28 C -4.972 15.3057 0.0 0
M  V30 29 O -6.5304 16.2333 0.0 0
M  V30 30 O -7.9033 20.5746 0.0 0
M  V30 31 C -8.5712 18.1628 0.0 0
M  V30 32 C -6.0666 14.3224 0.0 0
M  V30 33 C -4.3041 14.1369 0.0 0
M  V30 34 O -9.9997 18.5895 0.0 0
M  V30 35 O -0.742 8.7567 0.0 0
M  V30 36 C -2.152 8.3671 0.0 0
M  V30 37 O -3.3579 9.2762 0.0 0
M  V30 38 C -2.6529 7.0684 0.0 0
M  V30 39 C -4.5638 8.4784 0.0 0 CFG=1
M  V30 40 O -1.8552 5.9367 0.0 0
M  V30 41 C -4.1371 7.1241 0.0 0
M  V30 42 C -5.9924 8.9051 0.0 0 CFG=1
M  V30 43 O -5.0462 5.9924 0.0 0
M  V30 44 O -6.4191 10.3337 0.0 0
M  V30 45 C -7.087 7.9218 0.0 0
M  V30 46 C -7.9033 10.3893 0.0 0
M  V30 47 O -8.4042 8.6454 0.0 0
M  V30 48 C -9.3875 10.445 0.0 0
M  V30 49 C -8.33 11.8179 0.0 0
M  V30 50 C 0.1484 5.6399 0.0 0
M  V30 51 C -0.742 13.6545 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=1
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 8 12 CFG=3
M  V30 12 1 8 13
M  V30 13 1 9 14
M  V30 14 1 9 15
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 2 20 21
M  V30 20 1 21 22
M  V30 21 1 21 23
M  V30 22 1 24 22 CFG=1
M  V30 23 1 23 25
M  V30 24 2 23 26
M  V30 25 1 24 27
M  V30 26 1 25 28
M  V30 27 1 26 29
M  V30 28 1 27 30 CFG=3
M  V30 29 1 27 31
M  V30 30 1 28 32
M  V30 31 1 28 33
M  V30 32 1 31 34
M  V30 33 2 35 36
M  V30 34 1 36 37
M  V30 35 1 36 38
M  V30 36 1 39 37 CFG=1
M  V30 37 1 38 40
M  V30 38 2 38 41
M  V30 39 1 39 42
M  V30 40 1 41 43
M  V30 41 1 42 44 CFG=3
M  V30 42 1 42 45
M  V30 43 1 44 46
M  V30 44 1 45 47
M  V30 45 1 46 48
M  V30 46 1 46 49
M  V30 47 1 5 7
M  V30 48 1 9 10
M  V30 49 1 16 17
M  V30 50 1 24 26
M  V30 51 1 28 29
M  V30 52 1 39 41
M  V30 53 1 46 47
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(6 5 8 24 27 39 42)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00035001.cdx

>  <name>
US20220000752A1-20220106-C00014

>  <Row No>
732

$$$$
US20220000752A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.4504 -0.4279 0.0 0
M  V30 3 O -2.6868 0.4755 0.0 0
M  V30 4 C -1.9497 -1.807 0.0 0
M  V30 5 C -3.9233 -0.3566 0.0 0 CFG=2
M  V30 6 O -1.1175 -2.9721 0.0 0
M  V30 7 C -3.4715 -1.7714 0.0 0
M  V30 8 C -5.3975 0.0713 0.0 0 CFG=2
M  V30 9 O -4.375 -2.9365 0.0 0
M  V30 10 O -5.8255 1.5455 0.0 0
M  V30 11 C -6.4793 -0.9392 0.0 0
M  V30 12 O -7.9536 -0.5112 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=3
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 8 10 CFG=1
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 1 5 7
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 5 8)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000752A1-20220106-C00015

>  <Row No>
733

$$$$
US20220000753A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000753A1-20220106-C00003

>  <Row No>
734

$$$$
US20220000753A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 1.136 0.7477 0.0 0
M  V30 3 O -1.2223 -0.6615 0.0 0
M  V30 4 O 0.6615 -1.136 0.0 0 CHG=-1
M  V30 5 C -0.7477 1.2223 0.0 0
M  V30 6 C -2.5885 1.2655 0.0 0 CFG=1
M  V30 7 O -2.6316 2.6748 0.0 0
M  V30 8 C -4.4292 1.3086 0.0 0
M  V30 9 C -5.8385 1.3517 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 6 8 CFG=3
M  V30 8 1 8 9
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 6)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000753A1-20220106-C00004

>  <Row No>
735

$$$$
US20220000753A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000753A1-20220106-C00005

>  <Row No>
736

$$$$
US20220000754A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=15
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000754A1-20220106-C00002

>  <Row No>
737

$$$$
US20220000754A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000754A1-20220106-C00003

>  <Row No>
738

$$$$
US20220000754A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000754A1-20220106-C00004

>  <Row No>
739

$$$$
US20220000757A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000757A1-20220106-C00001

>  <Row No>
740

$$$$
US20220000757A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000757A1-20220106-C00002

>  <Row No>
741

$$$$
US20220000757A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 60 59 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0211 -1.3938 0.0 0
M  V30 3 O -1.4994 -1.3304 0.0 0
M  V30 4 C 0.2956 -0.7813 0.0 0
M  V30 5 C -3.759 -1.2671 0.0 0
M  V30 6 C 0.9714 -1.964 0.0 0
M  V30 7 C -5.6597 -1.2037 0.0 0
M  V30 8 C 2.3652 -1.9428 0.0 0
M  V30 9 O -6.969 -1.1403 0.0 0
M  V30 10 C 3.8857 -1.3304 0.0 0
M  V30 11 C -8.4473 -1.077 0.0 0
M  V30 12 C 5.7019 -1.3093 0.0 0
M  V30 13 C -8.5107 1.5838 0.0 0
M  V30 14 C -8.5107 -3.7379 0.0 0
M  V30 15 C 7.5181 -1.2882 0.0 0
M  V30 16 O -7.1591 1.6472 0.0 0
M  V30 17 O -7.1591 -3.6746 0.0 0
M  V30 18 C 9.3343 -1.2671 0.0 0
M  V30 19 C -5.9765 1.7105 0.0 0
M  V30 20 C -5.9765 -3.6112 0.0 0
M  V30 21 O 10.2846 -2.2174 0.0 0
M  V30 22 C 10.0312 -0.6124 0.0 0
M  V30 23 C -4.2025 1.7739 0.0 0
M  V30 24 C -4.2025 -3.5478 0.0 0
M  V30 25 ? 11.6362 -1.8373 0.0 0
M  V30 26 C 10.6647 -1.7528 0.0 0
M  V30 27 O -2.0696 1.8373 0.0 0
M  V30 28 O -2.0696 -3.4845 0.0 0
M  V30 29 C 12.0163 -1.6894 0.0 0
M  V30 30 C -0.718 1.9006 0.0 0
M  V30 31 C -0.718 -3.4211 0.0 0
M  V30 32 C 13.4524 -1.0348 0.0 0
M  V30 33 O -0.7813 3.3789 0.0 0
M  V30 34 C -0.4434 2.5553 0.0 0
M  V30 35 O -0.7813 -1.9428 0.0 0
M  V30 36 C -0.4434 -2.7665 0.0 0
M  V30 37 C 0.19 1.4149 0.0 0
M  V30 38 C 0.19 -3.9069 0.0 0
M  V30 39 C 1.5416 1.4782 0.0 0
M  V30 40 C 1.5416 -3.8435 0.0 0
M  V30 41 C 3.0199 2.1329 0.0 0
M  V30 42 C 3.0199 -3.1888 0.0 0
M  V30 43 C 4.7938 2.1963 0.0 0
M  V30 44 C 4.7938 -3.1255 0.0 0
M  V30 45 C 6.5678 2.2596 0.0 0
M  V30 46 C 6.5678 -3.0621 0.0 0
M  V30 47 C 8.3417 2.323 0.0 0
M  V30 48 C 8.3417 -2.9988 0.0 0
M  V30 49 O 8.9753 1.1826 0.0 0
M  V30 50 C 9.0386 2.9776 0.0 0
M  V30 51 O 8.9753 -4.1392 0.0 0
M  V30 52 C 9.0386 -2.3441 0.0 0
M  V30 53 ? 10.3268 1.2459 0.0 0
M  V30 54 C 9.6722 1.8373 0.0 0
M  V30 55 ? 10.3268 -4.0758 0.0 0
M  V30 56 C 9.6722 -3.4845 0.0 0
M  V30 57 C 11.0238 1.9006 0.0 0
M  V30 58 C 11.0238 -3.4211 0.0 0
M  V30 59 C 12.4598 2.5553 0.0 0
M  V30 60 C 12.4598 -2.7665 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 1 19 23
M  V30 23 1 20 24
M  V30 24 1 21 25
M  V30 25 1 22 26
M  V30 26 1 23 27
M  V30 27 1 24 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 28 31
M  V30 31 1 29 32
M  V30 32 2 30 33
M  V30 33 1 30 34
M  V30 34 2 31 35
M  V30 35 1 31 36
M  V30 36 1 34 37
M  V30 37 1 36 38
M  V30 38 1 37 39
M  V30 39 1 38 40
M  V30 40 1 39 41
M  V30 41 1 40 42
M  V30 42 1 41 43
M  V30 43 1 42 44
M  V30 44 1 43 45
M  V30 45 1 44 46
M  V30 46 1 45 47
M  V30 47 1 46 48
M  V30 48 1 47 49
M  V30 49 1 47 50
M  V30 50 1 48 51
M  V30 51 1 48 52
M  V30 52 1 49 53
M  V30 53 1 50 54
M  V30 54 1 51 55
M  V30 55 1 52 56
M  V30 56 1 54 57
M  V30 57 1 56 58
M  V30 58 1 57 59
M  V30 59 1 58 60
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000757A1-20220106-C00003

>  <Row No>
742

$$$$
US20220000757A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C -1.3409 0.7852 0.0 0
M  V30 3 C -0.0362 -1.4738 0.0 0
M  V30 4 C 1.2684 0.7852 0.0 0
M  V30 5 C -1.3771 2.3315 0.0 0
M  V30 6 C -1.3771 -2.1986 0.0 0
M  V30 7 C 1.2322 2.3315 0.0 0
M  V30 8 N -2.7181 3.1168 0.0 0
M  V30 9 N -1.4134 -3.6725 0.0 0
M  V30 10 C 2.5006 3.1168 0.0 0
M  V30 11 C -4.0591 2.3919 0.0 0
M  V30 12 C -2.7543 4.6631 0.0 0
M  V30 13 C 3.7691 2.3919 0.0 0
M  V30 14 C -5.4 3.1651 0.0 0
M  V30 15 C -4.0953 5.4483 0.0 0
M  V30 16 C 5.0376 3.1651 0.0 0
M  V30 17 N 6.3061 2.4402 0.0 0
M  V30 18 C 6.2698 0.9664 0.0 0
M  V30 19 C 7.5745 3.2255 0.0 0
M  V30 20 C 7.5383 0.2416 0.0 0
M  V30 21 C 8.843 2.5006 0.0 0
M  V30 22 N 7.502 -1.2322 0.0 0
M  V30 23 C 10.1115 3.2738 0.0 0
M  V30 24 C 11.3799 2.549 0.0 0
M  V30 25 C 12.6484 3.3342 0.0 0
M  V30 26 N 13.9169 2.6094 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000757A1-20220106-C00004

>  <Row No>
743

$$$$
US20220000757A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 112 111 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.7725 1.3191 0.0 0
M  V30 3 C 1.4499 0.0356 0.0 0
M  V30 4 C -2.2937 1.3548 0.0 0
M  V30 5 N -3.0543 2.674 0.0 0
M  V30 6 C -4.3735 1.949 0.0 0
M  V30 7 C -3.8268 3.9932 0.0 0
M  V30 8 C -4.4092 0.4991 0.0 0
M  V30 9 C -3.1019 5.3124 0.0 0
M  V30 10 O -5.7284 -0.2139 0.0 0
M  V30 11 N -3.8625 6.6316 0.0 0
M  V30 12 C -5.764 -1.6638 0.0 0
M  V30 13 C -2.4601 6.2751 0.0 0
M  V30 14 C -3.5059 8.1053 0.0 0
M  V30 15 C -1.4499 7.3566 0.0 0
M  V30 16 C -4.5874 9.1868 0.0 0
M  V30 17 O -0.0475 7.0 0.0 0
M  V30 18 N -4.2309 10.6605 0.0 0
M  V30 19 C 0.9626 8.0815 0.0 0
M  V30 20 C -5.5501 9.9355 0.0 0
M  V30 21 C -4.9915 11.9797 0.0 0
M  V30 22 C -6.8693 10.708 0.0 0
M  V30 23 C -4.2784 13.2989 0.0 0
M  V30 24 O -8.1885 9.9831 0.0 0
M  V30 25 N -5.0391 14.6181 0.0 0
M  V30 26 C -9.5077 10.7556 0.0 0
M  V30 27 C -3.6367 14.2616 0.0 0
M  V30 28 C -5.7997 15.9373 0.0 0
M  V30 29 C -2.6265 15.3431 0.0 0
M  V30 30 C -5.0866 17.2565 0.0 0
M  V30 31 O -1.2241 14.9865 0.0 0
M  V30 32 N -5.8472 18.5757 0.0 0
M  V30 33 C -0.2139 16.068 0.0 0
M  V30 34 C -7.1664 17.8626 0.0 0
M  V30 35 C -5.8829 20.0969 0.0 0
M  V30 36 C -8.4856 18.6351 0.0 0
M  V30 37 C -4.635 20.8576 0.0 0
M  V30 38 N -9.8048 17.922 0.0 0
M  V30 39 C -4.6706 22.3788 0.0 0
M  V30 40 C -10.2327 19.3957 0.0 0
M  V30 41 C -10.5773 16.6742 0.0 0
M  V30 42 N -3.4227 23.1513 0.0 0
M  V30 43 C -11.7064 19.8236 0.0 0
M  V30 44 C -12.0985 16.7098 0.0 0
M  V30 45 C -2.7097 24.4705 0.0 0
M  V30 46 C -2.0203 23.5791 0.0 0
M  V30 47 N -12.1342 21.2973 0.0 0
M  V30 48 N -12.8592 15.4619 0.0 0
M  V30 49 C -3.4703 25.7897 0.0 0
M  V30 50 C -1.0101 22.5689 0.0 0
M  V30 51 C -11.124 22.3788 0.0 0
M  V30 52 C -12.5621 22.771 0.0 0
M  V30 53 C -13.287 16.9356 0.0 0
M  V30 54 C -14.3329 15.1054 0.0 0
M  V30 55 N -2.7572 27.1089 0.0 0
M  V30 56 N 0.3921 22.9968 0.0 0
M  V30 57 C -11.5519 23.8525 0.0 0
M  V30 58 C -14.0358 23.1988 0.0 0
M  V30 59 C -14.7607 17.3635 0.0 0
M  V30 60 C -14.7607 13.703 0.0 0
M  V30 61 C -3.8387 28.1904 0.0 0
M  V30 62 C -3.185 28.5826 0.0 0
M  V30 63 C -0.3803 24.316 0.0 0
M  V30 64 C 1.64 22.2837 0.0 0
M  V30 65 O -10.5417 24.934 0.0 0
M  V30 66 N -14.4636 24.6725 0.0 0
M  V30 67 O -15.1886 18.8372 0.0 0
M  V30 68 N -16.2344 13.3464 0.0 0
M  V30 69 C -5.3124 27.8339 0.0 0
M  V30 70 C -2.1748 29.6641 0.0 0
M  V30 71 C 0.3446 25.6352 0.0 0
M  V30 72 C 2.8879 23.0562 0.0 0
M  V30 73 C -10.9695 26.4077 0.0 0
M  V30 74 C -14.8914 26.1462 0.0 0
M  V30 75 C -15.9373 25.1004 0.0 0
M  V30 76 C -16.6623 19.265 0.0 0
M  V30 77 C -15.8779 11.944 0.0 0
M  V30 78 C -17.5536 14.1071 0.0 0
M  V30 79 O -6.3939 28.9154 0.0 0
M  V30 80 N -2.6027 31.1378 0.0 0
M  V30 81 O -0.4278 26.9544 0.0 0
M  V30 82 N 4.1358 22.3431 0.0 0
M  V30 83 C -16.3651 26.5741 0.0 0
M  V30 84 C -17.0188 24.0902 0.0 0
M  V30 85 C -16.9594 10.9339 0.0 0
M  V30 86 C -18.8728 13.394 0.0 0
M  V30 87 C -7.8676 28.5588 0.0 0
M  V30 88 C -1.8777 32.457 0.0 0
M  V30 89 C -4.1239 31.1735 0.0 0
M  V30 90 C 0.2971 28.2736 0.0 0
M  V30 91 C 5.146 21.3329 0.0 0
M  V30 92 C 4.1002 23.8644 0.0 0
M  V30 93 O -16.793 28.0478 0.0 0
M  V30 94 O -18.4925 24.518 0.0 0
M  V30 95 O -16.6028 9.5315 0.0 0
M  V30 96 O -20.192 14.1546 0.0 0
M  V30 97 C -0.4278 32.4927 0.0 0
M  V30 98 C -4.8846 32.4927 0.0 0
M  V30 99 C 6.5484 21.7608 0.0 0
M  V30 100 C 5.3481 24.6369 0.0 0
M  V30 101 C -18.2667 28.4756 0.0 0
M  V30 102 C -19.574 23.5078 0.0 0
M  V30 103 C -17.6843 8.5213 0.0 0
M  V30 104 C -21.5112 13.4415 0.0 0
M  V30 105 O 0.2852 33.8119 0.0 0
M  V30 106 O -6.4058 32.5283 0.0 0
M  V30 107 O 7.5586 20.7506 0.0 0
M  V30 108 O 5.3124 26.1581 0.0 0
M  V30 109 C 1.7351 33.8475 0.0 0
M  V30 110 C -7.1664 33.8475 0.0 0
M  V30 111 C 8.961 21.1784 0.0 0
M  V30 112 C 6.5603 26.9306 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 4 5
M  V30 5 1 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 25 27
M  V30 27 1 25 28
M  V30 28 1 27 29
M  V30 29 1 28 30
M  V30 30 1 29 31
M  V30 31 1 30 32
M  V30 32 1 31 33
M  V30 33 1 32 34
M  V30 34 1 32 35
M  V30 35 1 34 36
M  V30 36 1 35 37
M  V30 37 1 36 38
M  V30 38 1 37 39
M  V30 39 1 38 40
M  V30 40 1 38 41
M  V30 41 1 39 42
M  V30 42 1 40 43
M  V30 43 1 41 44
M  V30 44 1 42 45
M  V30 45 1 42 46
M  V30 46 1 43 47
M  V30 47 1 44 48
M  V30 48 1 45 49
M  V30 49 1 46 50
M  V30 50 1 47 51
M  V30 51 1 47 52
M  V30 52 1 48 53
M  V30 53 1 48 54
M  V30 54 1 49 55
M  V30 55 1 50 56
M  V30 56 1 51 57
M  V30 57 1 52 58
M  V30 58 1 53 59
M  V30 59 1 54 60
M  V30 60 1 55 61
M  V30 61 1 55 62
M  V30 62 1 56 63
M  V30 63 1 56 64
M  V30 64 1 57 65
M  V30 65 1 58 66
M  V30 66 1 59 67
M  V30 67 1 60 68
M  V30 68 1 61 69
M  V30 69 1 62 70
M  V30 70 1 63 71
M  V30 71 1 64 72
M  V30 72 1 65 73
M  V30 73 1 66 74
M  V30 74 1 66 75
M  V30 75 1 67 76
M  V30 76 1 68 77
M  V30 77 1 68 78
M  V30 78 1 69 79
M  V30 79 1 70 80
M  V30 80 1 71 81
M  V30 81 1 72 82
M  V30 82 1 74 83
M  V30 83 1 75 84
M  V30 84 1 77 85
M  V30 85 1 78 86
M  V30 86 1 79 87
M  V30 87 1 80 88
M  V30 88 1 80 89
M  V30 89 1 81 90
M  V30 90 1 82 91
M  V30 91 1 82 92
M  V30 92 1 83 93
M  V30 93 1 84 94
M  V30 94 1 85 95
M  V30 95 1 86 96
M  V30 96 1 88 97
M  V30 97 1 89 98
M  V30 98 1 91 99
M  V30 99 1 92 100
M  V30 100 1 93 101
M  V30 101 1 94 102
M  V30 102 1 95 103
M  V30 103 1 96 104
M  V30 104 1 97 105
M  V30 105 1 98 106
M  V30 106 1 99 107
M  V30 107 1 100 108
M  V30 108 1 105 109
M  V30 109 1 106 110
M  V30 110 1 107 111
M  V30 111 1 108 112
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000757A1-20220106-C00005

>  <Row No>
744

$$$$
US20220000757A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C -0.7641 1.3476 0.0 0
M  V30 3 C 1.2642 -0.6946 0.0 0
M  V30 4 C -1.3476 -0.6946 0.0 0
M  V30 5 C -0.0694 2.6952 0.0 0
M  V30 6 C 2.5285 0.0833 0.0 0
M  V30 7 C -2.6952 0.0833 0.0 0
M  V30 8 N -0.8474 4.0429 0.0 0 CHG=1
M  V30 9 N 3.7928 -0.6112 0.0 0
M  V30 10 N -4.0429 -0.6112 0.0 0
M  V30 11 C -0.1528 5.3905 0.0 0
M  V30 12 C 5.0571 0.1667 0.0 0
M  V30 13 C -5.3905 0.1667 0.0 0
M  V30 14 C 6.3213 -0.5279 0.0 0
M  V30 15 N 7.5856 0.25 0.0 0
M  V30 16 C 8.8499 -0.4445 0.0 0
M  V30 17 C 10.1142 0.3334 0.0 0
M  V30 18 C 11.3785 -0.3612 0.0 0
M  V30 19 N 12.6427 0.4167 0.0 0
M  V30 20 C 12.351 -0.8474 0.0 0
M  V30 21 C 14.3933 1.1948 0.0 0
M  V30 22 C 13.0456 -2.1117 0.0 0
M  V30 23 C 15.6576 0.5001 0.0 0
M  V30 24 N 12.2676 -3.376 0.0 0 CHG=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000757A1-20220106-C00006

>  <Row No>
745

$$$$
US20220000757A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000757A1-20220106-C00007

>  <Row No>
746

$$$$
US20220000757A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00040001.cdx

>  <name>
US20220000757A1-20220106-C00008

>  <Row No>
747

$$$$
US20220000757A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00041001.cdx

>  <name>
US20220000757A1-20220106-C00009

>  <Row No>
748

$$$$
US20220000757A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00042001.cdx

>  <name>
US20220000757A1-20220106-C00010

>  <Row No>
749

$$$$
US20220000758A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000758A1-20220106-C00001

>  <Row No>
750

$$$$
US20220000758A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000758A1-20220106-C00002

>  <Row No>
751

$$$$
US20220000758A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -2.1617 0.6079 0.0 0
M  V30 3 C 1.199 0.0506 0.0 0
M  V30 4 C -2.8541 -0.439 0.0 0
M  V30 5 C 2.8034 0.1013 0.0 0
M  V30 6 C -3.8674 0.1688 0.0 0
M  V30 7 O 2.7528 -1.0977 0.0 0
M  V30 8 C 4.0363 -0.4053 0.0 0
M  V30 9 O 4.6274 0.7262 0.0 0
M  V30 10 C 6.5189 0.2195 0.0 0
M  V30 11 C 8.1233 0.2702 0.0 0
M  V30 12 C 9.7615 0.3208 0.0 0
M  V30 13 C 0.5404 0.4053 0.0 0
M  V30 14 C 5.6745 0.4053 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 2 11 12
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000758A1-20220106-C00003

>  <Row No>
752

$$$$
US20220000758A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000758A1-20220106-C00004

>  <Row No>
753

$$$$
US20220000759A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 17 16 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -3.5855 -0.6162 0.0 0
M  V30 3 O 0.5042 -0.9524 0.0 0
M  V30 4 C 0.056 -1.3726 0.0 0
M  V30 5 ? 0.112 0.9524 0.0 0
M  V30 6 Si -2.6331 0.056 0.0 0
M  V30 7 Si 2.6891 -0.084 0.0 0
M  V30 8 N -0.028 -2.4931 0.0 0
M  V30 9 C -2.9693 1.1765 0.0 0
M  V30 10 C -2.9693 -1.2045 0.0 0
M  V30 11 ? -4.4539 0.0 0.0 0
M  V30 12 C 2.6051 1.2045 0.0 0
M  V30 13 C 2.6051 -1.2045 0.0 0
M  V30 14 ? 4.706 0.0 0.0 0
M  V30 15 C -1.1485 -2.9973 0.0 0
M  V30 16 C -1.2325 -4.1178 0.0 0
M  V30 17 N -2.353 -4.622 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 7 13
M  V30 13 1 7 14
M  V30 14 1 8 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000759A1-20220106-C00001

>  <Row No>
754

$$$$
US20220000759A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 18 18 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 1.5334 0.0 0
M  V30 3 C -1.3657 2.3122 0.0 0
M  V30 4 C 1.2219 2.3122 0.0 0
M  V30 5 O -2.6955 1.5933 0.0 0
M  V30 6 C -1.4017 3.8456 0.0 0
M  V30 7 C 1.186 3.8456 0.0 0
M  V30 8 C 2.4799 1.5933 0.0 0
M  V30 9 C -2.7195 0.1317 0.0 0
M  V30 10 O -2.7315 4.6244 0.0 0
M  V30 11 C -0.1437 4.6244 0.0 0
M  V30 12 C 2.4439 4.6244 0.0 0
M  V30 13 C 3.7378 2.3721 0.0 0
M  V30 14 C -4.1092 3.9894 0.0 0
M  V30 15 O -0.1797 6.1579 0.0 0
M  V30 16 C 4.9958 1.6532 0.0 0
M  V30 17 C 6.2537 2.42 0.0 0
M  V30 18 C 4.9598 0.1916 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 8 13
M  V30 13 1 10 14
M  V30 14 2 11 15
M  V30 15 2 13 16
M  V30 16 1 16 17
M  V30 17 1 16 18
M  V30 18 1 7 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000759A1-20220106-C00002

>  <Row No>
755

$$$$
US20220000759A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 17 16 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Si 0.0 0.0 0.0 0
M  V30 2 O -3.5855 -0.6162 0.0 0
M  V30 3 O 0.5042 -0.9524 0.0 0
M  V30 4 C 0.056 -1.3726 0.0 0
M  V30 5 ? 0.112 0.9524 0.0 0
M  V30 6 Si -2.6331 0.056 0.0 0
M  V30 7 Si 2.6891 -0.084 0.0 0
M  V30 8 N -0.028 -2.4931 0.0 0
M  V30 9 C -2.9693 1.1765 0.0 0
M  V30 10 C -2.9693 -1.2045 0.0 0
M  V30 11 ? -4.4539 0.0 0.0 0
M  V30 12 C 2.6051 1.2045 0.0 0
M  V30 13 C 2.6051 -1.2045 0.0 0
M  V30 14 ? 4.706 0.0 0.0 0
M  V30 15 C -1.1485 -2.9973 0.0 0
M  V30 16 C -1.2325 -4.1178 0.0 0
M  V30 17 N -2.353 -4.622 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 1 7 13
M  V30 13 1 7 14
M  V30 14 1 8 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000759A1-20220106-C00003

>  <Row No>
756

$$$$
US20220000762A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000762A1-20220106-C00001

>  <Row No>
757

$$$$
US20220000762A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 14 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.9982 0.0468 0.0 0
M  V30 3 C -3.5281 0.0936 0.0 0 CFG=2
M  V30 4 C -3.5749 -1.3425 0.0 0
M  V30 5 C -5.058 0.1405 0.0 0
M  V30 6 C -2.3416 -2.0606 0.0 0
M  V30 7 C -5.8697 -1.0927 0.0 0
M  V30 8 C -2.3885 -3.4969 0.0 0
M  V30 9 C -7.3996 -1.0459 0.0 0
M  V30 10 C -1.1552 -4.215 0.0 0
M  V30 11 C -8.2114 -2.2792 0.0 0
M  V30 12 C -1.202 -5.6512 0.0 0
M  V30 13 C 0.0312 -6.3693 0.0 0
M  V30 14 C -0.0156 -7.8055 0.0 0
M  V30 15 C 1.2176 -8.5236 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 4 1 3 5 CFG=3
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 3)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000762A1-20220106-C00002

>  <Row No>
758

$$$$
US20220000762A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 19 18 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -2.0078 0.047 0.0 0
M  V30 3 C -3.545 0.0941 0.0 0 CFG=2
M  V30 4 C -3.592 -1.3489 0.0 0
M  V30 5 C -5.0822 0.1411 0.0 0
M  V30 6 C -2.3528 -2.0705 0.0 0
M  V30 7 C -5.8979 -1.098 0.0 0
M  V30 8 C -2.3999 -3.5136 0.0 0
M  V30 9 C -7.4351 -1.0509 0.0 0
M  V30 10 C -1.1607 -4.2352 0.0 0
M  V30 11 C -8.2508 -2.2901 0.0 0
M  V30 12 C -1.2078 -5.6783 0.0 0
M  V30 13 C -9.788 -2.243 0.0 0
M  V30 14 C 0.0313 -6.3998 0.0 0
M  V30 15 C -10.6037 -3.4822 0.0 0
M  V30 16 C -0.0156 -7.8429 0.0 0
M  V30 17 C 1.2235 -8.5645 0.0 0
M  V30 18 C 1.1764 -10.0076 0.0 0
M  V30 19 C 2.4156 -10.7292 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 4 1 3 5 CFG=3
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 3)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000762A1-20220106-C00003

>  <Row No>
759

$$$$
US20220000772A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 40 44 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.5421 0.0361 0.0 0
M  V30 3 C -2.4577 -1.1445 0.0 0
M  V30 4 C -2.4577 1.2891 0.0 0
M  V30 5 C -3.9276 -0.6385 0.0 0
M  V30 6 C -2.0963 -2.5662 0.0 0
M  V30 7 C -3.9276 0.8554 0.0 0
M  V30 8 C -5.2649 -1.3734 0.0 0
M  V30 9 N -0.6746 -2.9276 0.0 0
M  V30 10 C -3.1926 -3.5902 0.0 0
M  V30 11 C -5.2649 1.6385 0.0 0
M  V30 12 C -6.6022 -0.5903 0.0 0
M  V30 13 C -0.3132 -4.3492 0.0 0
M  V30 14 C -4.6866 -3.1565 0.0 0
M  V30 15 C -2.8312 -5.0119 0.0 0
M  V30 16 C -6.6022 0.9035 0.0 0
M  V30 17 C -1.4096 -5.3733 0.0 0
M  V30 18 C 1.1084 -4.7107 0.0 0
M  V30 19 C -5.7829 -4.1806 0.0 0
M  V30 20 C -3.9276 -6.0359 0.0 0
M  V30 21 C -7.9395 1.6867 0.0 0
M  V30 22 C -1.0481 -6.795 0.0 0
M  V30 23 C 1.4698 -6.1323 0.0 0
M  V30 24 C -5.4215 -5.6022 0.0 0
M  V30 25 O -7.9757 3.2288 0.0 0
M  V30 26 O -9.2768 0.9517 0.0 0
M  V30 27 C 0.3734 -7.1564 0.0 0
M  V30 28 C -10.6141 1.7348 0.0 0
M  V30 29 N 0.7349 -8.578 0.0 0
M  V30 30 C 2.1565 -8.9395 0.0 0
M  V30 31 C -0.3614 -9.6021 0.0 0
M  V30 32 O 2.518 -10.3611 0.0 0
M  V30 33 C 3.1806 -7.8431 0.0 0
M  V30 34 N 4.6022 -8.2046 0.0 0
M  V30 35 C 4.9637 -9.6262 0.0 0
M  V30 36 C 5.6263 -7.1082 0.0 0
M  V30 37 C 6.3853 -9.9877 0.0 0
M  V30 38 C 7.048 -7.4696 0.0 0
M  V30 39 N 7.4094 -8.8913 0.0 0
M  V30 40 C 8.8311 -9.2527 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 9 13
M  V30 13 2 10 14
M  V30 14 1 10 15
M  V30 15 2 11 16
M  V30 16 2 13 17
M  V30 17 1 13 18
M  V30 18 1 14 19
M  V30 19 2 15 20
M  V30 20 1 16 21
M  V30 21 1 17 22
M  V30 22 2 18 23
M  V30 23 2 19 24
M  V30 24 2 21 25
M  V30 25 1 21 26
M  V30 26 2 22 27
M  V30 27 1 26 28
M  V30 28 1 27 29
M  V30 29 1 29 30
M  V30 30 1 29 31
M  V30 31 2 30 32
M  V30 32 1 30 33
M  V30 33 1 33 34
M  V30 34 1 34 35
M  V30 35 1 34 36
M  V30 36 1 35 37
M  V30 37 1 36 38
M  V30 38 1 37 39
M  V30 39 1 39 40
M  V30 40 2 5 7
M  V30 41 1 12 16
M  V30 42 1 20 24
M  V30 43 1 23 27
M  V30 44 1 38 39
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000772A1-20220106-C00001

>  <Row No>
760

$$$$
US20220000776A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 32 33 0 0 0
M  V30 BEGIN ATOM
M  V30 1 I 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4679 0.0 0
M  V30 3 C 1.2273 -2.1899 0.0 0
M  V30 4 C -1.3717 -2.1899 0.0 0
M  V30 5 O 2.4907 -1.4198 0.0 0
M  V30 6 C 1.1912 -3.6578 0.0 0
M  V30 7 C -1.4078 -3.6578 0.0 0
M  V30 8 C 3.7541 -2.1417 0.0 0
M  V30 9 I 2.4546 -4.3798 0.0 0
M  V30 10 C -0.1443 -4.3798 0.0 0
M  V30 11 C -2.7434 -4.3798 0.0 0
M  V30 12 C 5.0175 -1.3596 0.0 0
M  V30 13 O -2.7795 -5.8478 0.0 0
M  V30 14 C -4.079 -3.5977 0.0 0
M  V30 15 N 6.2809 -2.0816 0.0 0
M  V30 16 C -5.5469 -4.0308 0.0 0
M  V30 17 C -4.1151 -2.0575 0.0 0
M  V30 18 C 7.5443 -1.2995 0.0 0
M  V30 19 C 6.2448 -3.5495 0.0 0
M  V30 20 C -6.4614 -2.7795 0.0 0
M  V30 21 C -6.2087 -5.3665 0.0 0
M  V30 22 O -5.583 -1.5521 0.0 0
M  V30 23 C -2.8517 -1.2754 0.0 0
M  V30 24 C 7.5082 0.2406 0.0 0
M  V30 25 C 7.5082 -4.2715 0.0 0
M  V30 26 C -7.9895 -2.8998 0.0 0
M  V30 27 C -7.7369 -5.4868 0.0 0
M  V30 28 C -2.8878 0.2647 0.0 0
M  V30 29 C -8.6513 -4.2354 0.0 0
M  V30 30 C -1.6243 1.0468 0.0 0
M  V30 31 C -1.6604 2.5869 0.0 0
M  V30 32 Cl 3.7541 -5.0055 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 14 16
M  V30 16 2 14 17
M  V30 17 1 15 18
M  V30 18 1 15 19
M  V30 19 2 16 20
M  V30 20 1 16 21
M  V30 21 1 17 22
M  V30 22 1 17 23
M  V30 23 1 18 24
M  V30 24 1 19 25
M  V30 25 1 20 26
M  V30 26 2 21 27
M  V30 27 1 23 28
M  V30 28 2 26 29
M  V30 29 1 28 30
M  V30 30 1 30 31
M  V30 31 1 7 10
M  V30 32 1 20 22
M  V30 33 1 27 29
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000776A1-20220106-C00001

>  <Row No>
761

$$$$
US20220000778A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 42 41 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0365 -1.4857 0.0 0
M  V30 3 O 1.2421 -2.2163 0.0 0
M  V30 4 C -1.3882 -2.2163 0.0 0
M  V30 5 C 2.5208 -1.4248 0.0 0 CFG=2
M  V30 6 C -2.74 -1.4248 0.0 0
M  V30 7 C 3.7995 -2.1555 0.0 0
M  V30 8 C 2.4843 0.1339 0.0 0
M  V30 9 C -4.0917 -2.1555 0.0 0
M  V30 10 C 5.0782 -1.3639 0.0 0
M  V30 11 C 3.7629 -3.6412 0.0 0
M  V30 12 C 3.7629 0.9255 0.0 0
M  V30 13 C -5.4435 -1.3639 0.0 0
M  V30 14 C 6.3569 -2.0946 0.0 0
M  V30 15 C 5.0416 -4.384 0.0 0
M  V30 16 C 5.0416 0.1826 0.0 0
M  V30 17 N -6.7953 -2.0946 0.0 0
M  V30 18 C 7.6355 -1.303 0.0 0
M  V30 19 C 6.3203 -3.5925 0.0 0
M  V30 20 C 6.3203 0.9742 0.0 0
M  V30 21 C -8.147 -1.303 0.0 0
M  V30 22 C -6.8318 -3.5803 0.0 0
M  V30 23 C 8.9142 -2.0337 0.0 0
M  V30 24 C 7.599 -4.3353 0.0 0
M  V30 25 C 7.806 1.0107 0.0 0
M  V30 26 C 10.3999 -1.9971 0.0 0
M  V30 27 C 9.0847 -4.2988 0.0 0
M  V30 28 C 9.0847 0.2679 0.0 0
M  V30 29 C 11.6786 -1.2056 0.0 0
M  V30 30 C 10.3634 -3.5072 0.0 0
M  V30 31 C 10.3634 1.0594 0.0 0
M  V30 32 C 12.9573 -1.9362 0.0 0
M  V30 33 C 11.6421 -4.2501 0.0 0
M  V30 34 C 11.6421 0.3166 0.0 0
M  V30 35 C 14.236 -1.1447 0.0 0
M  V30 36 C 12.9208 -3.4585 0.0 0
M  V30 37 C 12.9208 1.1081 0.0 0
M  V30 38 C 15.5147 -1.8754 0.0 0
M  V30 39 C 14.1995 -4.2013 0.0 0
M  V30 40 C 14.1995 0.3653 0.0 0
M  V30 41 C 16.7934 -1.096 0.0 0
M  V30 42 C 15.4782 -3.4098 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=1
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 1 15 19
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 1 17 22
M  V30 22 1 18 23
M  V30 23 1 19 24
M  V30 24 2 20 25
M  V30 25 2 23 26
M  V30 26 2 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 28 31
M  V30 31 1 29 32
M  V30 32 1 30 33
M  V30 33 1 31 34
M  V30 34 1 32 35
M  V30 35 1 33 36
M  V30 36 1 34 37
M  V30 37 1 35 38
M  V30 38 1 36 39
M  V30 39 1 37 40
M  V30 40 1 38 41
M  V30 41 1 39 42
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 5)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000778A1-20220106-C00001

>  <Row No>
762

$$$$
US20220000778A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 42 41 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0365 -1.4857 0.0 0
M  V30 3 O 1.2421 -2.2163 0.0 0
M  V30 4 C -1.3882 -2.2163 0.0 0
M  V30 5 C 2.5208 -1.4248 0.0 0 CFG=2
M  V30 6 C -2.74 -1.4248 0.0 0
M  V30 7 C 3.7995 -2.1555 0.0 0
M  V30 8 C 2.4843 0.1339 0.0 0
M  V30 9 C -4.0917 -2.1555 0.0 0
M  V30 10 C 5.0782 -1.3639 0.0 0
M  V30 11 C 3.7629 -3.6412 0.0 0
M  V30 12 C 3.7629 0.9255 0.0 0
M  V30 13 C -5.4435 -1.3639 0.0 0
M  V30 14 C 6.3569 -2.0946 0.0 0
M  V30 15 C 5.0416 -4.384 0.0 0
M  V30 16 C 5.0416 0.1826 0.0 0
M  V30 17 N -6.7953 -2.0946 0.0 0
M  V30 18 C 7.6355 -1.303 0.0 0
M  V30 19 C 6.3203 -3.5925 0.0 0
M  V30 20 C 6.3203 0.9742 0.0 0
M  V30 21 C -8.147 -1.303 0.0 0
M  V30 22 C -6.8318 -3.5803 0.0 0
M  V30 23 C 8.9142 -2.0337 0.0 0
M  V30 24 C 7.599 -4.3353 0.0 0
M  V30 25 C 7.806 1.0107 0.0 0
M  V30 26 C 10.3999 -1.9971 0.0 0
M  V30 27 C 9.0847 -4.2988 0.0 0
M  V30 28 C 9.0847 0.2679 0.0 0
M  V30 29 C 11.6786 -1.2056 0.0 0
M  V30 30 C 10.3634 -3.5072 0.0 0
M  V30 31 C 10.3634 1.0594 0.0 0
M  V30 32 C 12.9573 -1.9362 0.0 0
M  V30 33 C 11.6421 -4.2501 0.0 0
M  V30 34 C 11.6421 0.3166 0.0 0
M  V30 35 C 14.236 -1.1447 0.0 0
M  V30 36 C 12.9208 -3.4585 0.0 0
M  V30 37 C 12.9208 1.1081 0.0 0
M  V30 38 C 15.5147 -1.8754 0.0 0
M  V30 39 C 14.1995 -4.2013 0.0 0
M  V30 40 C 14.1995 0.3653 0.0 0
M  V30 41 C 16.7934 -1.096 0.0 0
M  V30 42 C 15.4782 -3.4098 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=1
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 1 15 19
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 1 17 22
M  V30 22 1 18 23
M  V30 23 1 19 24
M  V30 24 2 20 25
M  V30 25 2 23 26
M  V30 26 2 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 28 31
M  V30 31 1 29 32
M  V30 32 1 30 33
M  V30 33 1 31 34
M  V30 34 1 32 35
M  V30 35 1 33 36
M  V30 36 1 34 37
M  V30 37 1 35 38
M  V30 38 1 36 39
M  V30 39 1 37 40
M  V30 40 1 38 41
M  V30 41 1 39 42
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 5)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000778A1-20220106-C00002

>  <Row No>
763

$$$$
US20220000778A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 42 41 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0365 -1.4857 0.0 0
M  V30 3 O 1.2421 -2.2163 0.0 0
M  V30 4 C -1.3882 -2.2163 0.0 0
M  V30 5 C 2.5208 -1.4248 0.0 0 CFG=2
M  V30 6 C -2.74 -1.4248 0.0 0
M  V30 7 C 3.7995 -2.1555 0.0 0
M  V30 8 C 2.4843 0.1339 0.0 0
M  V30 9 C -4.0917 -2.1555 0.0 0
M  V30 10 C 5.0782 -1.3639 0.0 0
M  V30 11 C 3.7629 -3.6412 0.0 0
M  V30 12 C 3.7629 0.9255 0.0 0
M  V30 13 C -5.4435 -1.3639 0.0 0
M  V30 14 C 6.3569 -2.0946 0.0 0
M  V30 15 C 5.0416 -4.384 0.0 0
M  V30 16 C 5.0416 0.1826 0.0 0
M  V30 17 N -6.7953 -2.0946 0.0 0
M  V30 18 C 7.6355 -1.303 0.0 0
M  V30 19 C 6.3203 -3.5925 0.0 0
M  V30 20 C 6.3203 0.9742 0.0 0
M  V30 21 C -8.147 -1.303 0.0 0
M  V30 22 C -6.8318 -3.5803 0.0 0
M  V30 23 C 8.9142 -2.0337 0.0 0
M  V30 24 C 7.599 -4.3353 0.0 0
M  V30 25 C 7.806 1.0107 0.0 0
M  V30 26 C 10.3999 -1.9971 0.0 0
M  V30 27 C 9.0847 -4.2988 0.0 0
M  V30 28 C 9.0847 0.2679 0.0 0
M  V30 29 C 11.6786 -1.2056 0.0 0
M  V30 30 C 10.3634 -3.5072 0.0 0
M  V30 31 C 10.3634 1.0594 0.0 0
M  V30 32 C 12.9573 -1.9362 0.0 0
M  V30 33 C 11.6421 -4.2501 0.0 0
M  V30 34 C 11.6421 0.3166 0.0 0
M  V30 35 C 14.236 -1.1447 0.0 0
M  V30 36 C 12.9208 -3.4585 0.0 0
M  V30 37 C 12.9208 1.1081 0.0 0
M  V30 38 C 15.5147 -1.8754 0.0 0
M  V30 39 C 14.1995 -4.2013 0.0 0
M  V30 40 C 14.1995 0.3653 0.0 0
M  V30 41 C 16.7934 -1.096 0.0 0
M  V30 42 C 15.4782 -3.4098 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=1
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 1 15 19
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 1 17 22
M  V30 22 1 18 23
M  V30 23 1 19 24
M  V30 24 2 20 25
M  V30 25 2 23 26
M  V30 26 2 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 28 31
M  V30 31 1 29 32
M  V30 32 1 30 33
M  V30 33 1 31 34
M  V30 34 1 32 35
M  V30 35 1 33 36
M  V30 36 1 34 37
M  V30 37 1 35 38
M  V30 38 1 36 39
M  V30 39 1 37 40
M  V30 40 1 38 41
M  V30 41 1 39 42
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 5)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000778A1-20220106-C00003

>  <Row No>
764

$$$$
US20220000778A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 44 43 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0345 -1.4496 0.0 0
M  V30 3 O 1.2195 -2.1398 0.0 0
M  V30 4 N -1.3575 -2.1398 0.0 0
M  V30 5 C 2.4735 -1.3575 0.0 0
M  V30 6 C -2.6806 -1.3575 0.0 0
M  V30 7 C 3.7275 -2.0478 0.0 0
M  V30 8 C -4.0036 -2.0478 0.0 0 CFG=2
M  V30 9 O 4.9815 -1.2655 0.0 0
M  V30 10 O -4.0381 -3.4974 0.0 0
M  V30 11 C -5.3267 -1.2655 0.0 0
M  V30 12 C 6.2356 -1.9558 0.0 0
M  V30 13 C -5.3612 -4.1877 0.0 0
M  V30 14 O -6.6497 -1.9558 0.0 0
M  V30 15 C 7.4896 -1.1734 0.0 0
M  V30 16 C -6.6843 -3.4054 0.0 0
M  V30 17 C -7.9728 -1.1734 0.0 0
M  V30 18 O 8.7436 -1.8637 0.0 0
M  V30 19 C -8.0073 -4.0957 0.0 0
M  V30 20 C -9.2959 -1.8637 0.0 0
M  V30 21 C 9.9976 -1.0814 0.0 0
M  V30 22 C -9.3304 -3.3133 0.0 0
M  V30 23 C -10.6189 -1.0814 0.0 0
M  V30 24 C -10.6534 -4.0036 0.0 0
M  V30 25 C -11.942 -1.7717 0.0 0
M  V30 26 C -11.9765 -3.2213 0.0 0
M  V30 27 C -13.265 -0.9894 0.0 0
M  V30 28 C -13.2995 -3.9116 0.0 0
M  V30 29 C -14.5881 -1.6797 0.0 0
M  V30 30 C -14.6226 -3.1293 0.0 0
M  V30 31 C -15.9111 -0.8973 0.0 0
M  V30 32 C -15.9456 -3.8196 0.0 0
M  V30 33 C -17.2342 -1.5876 0.0 0
M  V30 34 C -17.2687 -3.0372 0.0 0
M  V30 35 C -18.5572 -0.8053 0.0 0
M  V30 36 C -18.5918 -3.7275 0.0 0
M  V30 37 C -19.8803 -1.4956 0.0 0
M  V30 38 C -19.9148 -2.9452 0.0 0
M  V30 39 C -21.2033 -0.7132 0.0 0
M  V30 40 C -21.2379 -3.6355 0.0 0
M  V30 41 C -22.5264 -1.4035 0.0 0
M  V30 42 C -22.5609 -2.8531 0.0 0
M  V30 43 C -23.8495 -0.6212 0.0 0
M  V30 44 C -25.1725 -1.3115 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 8 10 CFG=3
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 25 27
M  V30 27 1 26 28
M  V30 28 1 27 29
M  V30 29 1 28 30
M  V30 30 1 29 31
M  V30 31 1 30 32
M  V30 32 1 31 33
M  V30 33 1 32 34
M  V30 34 1 33 35
M  V30 35 1 34 36
M  V30 36 1 35 37
M  V30 37 1 36 38
M  V30 38 1 37 39
M  V30 39 1 38 40
M  V30 40 1 39 41
M  V30 41 1 40 42
M  V30 42 1 41 43
M  V30 43 1 43 44
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 8)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000778A1-20220106-C00004

>  <Row No>
765

$$$$
US20220000778A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 42 41 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0365 -1.4857 0.0 0
M  V30 3 O 1.2421 -2.2163 0.0 0
M  V30 4 C -1.3882 -2.2163 0.0 0
M  V30 5 C 2.5208 -1.4248 0.0 0 CFG=2
M  V30 6 C -2.74 -1.4248 0.0 0
M  V30 7 C 3.7995 -2.1555 0.0 0
M  V30 8 C 2.4843 0.1339 0.0 0
M  V30 9 C -4.0917 -2.1555 0.0 0
M  V30 10 C 5.0782 -1.3639 0.0 0
M  V30 11 C 3.7629 -3.6412 0.0 0
M  V30 12 C 3.7629 0.9255 0.0 0
M  V30 13 C -5.4435 -1.3639 0.0 0
M  V30 14 C 6.3569 -2.0946 0.0 0
M  V30 15 C 5.0416 -4.384 0.0 0
M  V30 16 C 5.0416 0.1826 0.0 0
M  V30 17 N -6.7953 -2.0946 0.0 0
M  V30 18 C 7.6355 -1.303 0.0 0
M  V30 19 C 6.3203 -3.5925 0.0 0
M  V30 20 C 6.3203 0.9742 0.0 0
M  V30 21 C -8.147 -1.303 0.0 0
M  V30 22 C -6.8318 -3.5803 0.0 0
M  V30 23 C 8.9142 -2.0337 0.0 0
M  V30 24 C 7.599 -4.3353 0.0 0
M  V30 25 C 7.806 1.0107 0.0 0
M  V30 26 C 10.3999 -1.9971 0.0 0
M  V30 27 C 9.0847 -4.2988 0.0 0
M  V30 28 C 9.0847 0.2679 0.0 0
M  V30 29 C 11.6786 -1.2056 0.0 0
M  V30 30 C 10.3634 -3.5072 0.0 0
M  V30 31 C 10.3634 1.0594 0.0 0
M  V30 32 C 12.9573 -1.9362 0.0 0
M  V30 33 C 11.6421 -4.2501 0.0 0
M  V30 34 C 11.6421 0.3166 0.0 0
M  V30 35 C 14.236 -1.1447 0.0 0
M  V30 36 C 12.9208 -3.4585 0.0 0
M  V30 37 C 12.9208 1.1081 0.0 0
M  V30 38 C 15.5147 -1.8754 0.0 0
M  V30 39 C 14.1995 -4.2013 0.0 0
M  V30 40 C 14.1995 0.3653 0.0 0
M  V30 41 C 16.7934 -1.096 0.0 0
M  V30 42 C 15.4782 -3.4098 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=1
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 1 15 19
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 1 17 22
M  V30 22 1 18 23
M  V30 23 1 19 24
M  V30 24 2 20 25
M  V30 25 2 23 26
M  V30 26 2 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 28 31
M  V30 31 1 29 32
M  V30 32 1 30 33
M  V30 33 1 31 34
M  V30 34 1 32 35
M  V30 35 1 33 36
M  V30 36 1 34 37
M  V30 37 1 35 38
M  V30 38 1 36 39
M  V30 39 1 37 40
M  V30 40 1 38 41
M  V30 41 1 39 42
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 5)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000778A1-20220106-C00005

>  <Row No>
766

$$$$
US20220000778A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 42 41 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0365 -1.4857 0.0 0
M  V30 3 O 1.2421 -2.2163 0.0 0
M  V30 4 C -1.3882 -2.2163 0.0 0
M  V30 5 C 2.5208 -1.4248 0.0 0 CFG=2
M  V30 6 C -2.74 -1.4248 0.0 0
M  V30 7 C 3.7995 -2.1555 0.0 0
M  V30 8 C 2.4843 0.1339 0.0 0
M  V30 9 C -4.0917 -2.1555 0.0 0
M  V30 10 C 5.0782 -1.3639 0.0 0
M  V30 11 C 3.7629 -3.6412 0.0 0
M  V30 12 C 3.7629 0.9255 0.0 0
M  V30 13 C -5.4435 -1.3639 0.0 0
M  V30 14 C 6.3569 -2.0946 0.0 0
M  V30 15 C 5.0416 -4.384 0.0 0
M  V30 16 C 5.0416 0.1826 0.0 0
M  V30 17 N -6.7953 -2.0946 0.0 0
M  V30 18 C 7.6355 -1.303 0.0 0
M  V30 19 C 6.3203 -3.5925 0.0 0
M  V30 20 C 6.3203 0.9742 0.0 0
M  V30 21 C -8.147 -1.303 0.0 0
M  V30 22 C -6.8318 -3.5803 0.0 0
M  V30 23 C 8.9142 -2.0337 0.0 0
M  V30 24 C 7.599 -4.3353 0.0 0
M  V30 25 C 7.806 1.0107 0.0 0
M  V30 26 C 10.3999 -1.9971 0.0 0
M  V30 27 C 9.0847 -4.2988 0.0 0
M  V30 28 C 9.0847 0.2679 0.0 0
M  V30 29 C 11.6786 -1.2056 0.0 0
M  V30 30 C 10.3634 -3.5072 0.0 0
M  V30 31 C 10.3634 1.0594 0.0 0
M  V30 32 C 12.9573 -1.9362 0.0 0
M  V30 33 C 11.6421 -4.2501 0.0 0
M  V30 34 C 11.6421 0.3166 0.0 0
M  V30 35 C 14.236 -1.1447 0.0 0
M  V30 36 C 12.9208 -3.4585 0.0 0
M  V30 37 C 12.9208 1.1081 0.0 0
M  V30 38 C 15.5147 -1.8754 0.0 0
M  V30 39 C 14.1995 -4.2013 0.0 0
M  V30 40 C 14.1995 0.3653 0.0 0
M  V30 41 C 16.7934 -1.096 0.0 0
M  V30 42 C 15.4782 -3.4098 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=1
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 14 18
M  V30 18 1 15 19
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 1 17 22
M  V30 22 1 18 23
M  V30 23 1 19 24
M  V30 24 2 20 25
M  V30 25 2 23 26
M  V30 26 2 24 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 1 28 31
M  V30 31 1 29 32
M  V30 32 1 30 33
M  V30 33 1 31 34
M  V30 34 1 32 35
M  V30 35 1 33 36
M  V30 36 1 34 37
M  V30 37 1 35 38
M  V30 38 1 36 39
M  V30 39 1 37 40
M  V30 40 1 38 41
M  V30 41 1 39 42
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 5)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000778A1-20220106-C00006

>  <Row No>
767

$$$$
US20220000781A9-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000781A9-20220106-C00001

>  <Row No>
768

$$$$
US20220000786A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 36 39 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0358 -1.4952 0.0 0
M  V30 3 O 1.256 -2.213 0.0 0
M  V30 4 C -1.3637 -2.201 0.0 0 CFG=1
M  V30 5 O -2.1532 -3.4571 0.0 0
M  V30 6 C -2.6915 -1.4115 0.0 0
M  V30 7 C -3.481 -4.1628 0.0 0
M  V30 8 C -4.0193 -2.1173 0.0 0
M  V30 9 C -3.5169 -5.6222 0.0 0
M  V30 10 C -4.8088 -3.3853 0.0 0
M  V30 11 C -4.8447 -6.328 0.0 0
M  V30 12 C -6.1366 -4.0911 0.0 0
M  V30 13 C -6.1725 -5.5385 0.0 0
M  V30 14 C -4.8806 -7.7874 0.0 0
M  V30 15 N -6.2084 -8.4932 0.0 0
M  V30 16 C -6.2443 -9.9526 0.0 0
M  V30 17 C -7.5362 -7.7037 0.0 0
M  V30 18 O -7.4884 -10.8019 0.0 0
M  V30 19 N -5.072 -10.8019 0.0 0
M  V30 20 C -8.864 -8.4094 0.0 0
M  V30 21 C -7.0697 -12.1895 0.0 0
M  V30 22 C -5.5624 -12.1895 0.0 0
M  V30 23 C -10.1918 -7.6199 0.0 0
M  V30 24 C -7.8592 -13.4456 0.0 0
M  V30 25 C -4.8566 -13.4456 0.0 0
M  V30 26 O -11.5196 -8.3257 0.0 0
M  V30 27 C -7.1534 -14.7016 0.0 0
M  V30 28 C -5.6462 -14.7016 0.0 0
M  V30 29 C -12.8475 -7.5482 0.0 0
M  V30 30 C -12.8833 -6.017 0.0 0
M  V30 31 C -14.1753 -8.2539 0.0 0
M  V30 32 C -14.2112 -5.2394 0.0 0
M  V30 33 C -15.5031 -7.4764 0.0 0
M  V30 34 C -15.539 -5.9452 0.0 0
M  V30 35 O -16.8668 -5.1677 0.0 0
M  V30 36 C -18.1946 -5.8734 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 4 5 CFG=1
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 7 10
M  V30 10 1 9 11
M  V30 11 2 10 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 16 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 21 24
M  V30 24 1 22 25
M  V30 25 1 23 26
M  V30 26 2 24 27
M  V30 27 2 25 28
M  V30 28 1 26 29
M  V30 29 2 29 30
M  V30 30 1 29 31
M  V30 31 1 30 32
M  V30 32 2 31 33
M  V30 33 2 32 34
M  V30 34 1 34 35
M  V30 35 1 35 36
M  V30 36 1 12 13
M  V30 37 2 21 22
M  V30 38 1 27 28
M  V30 39 1 33 34
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 4)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000786A1-20220106-C00001

>  <Row No>
769

$$$$
US20220000787A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.1824 0.7883 0.0 0
M  V30 3 C 2.3649 0.1182 0.0 0
M  V30 4 C 1.1233 2.3255 0.0 0
M  V30 5 C 3.5473 0.9065 0.0 0
M  V30 6 C 2.3058 3.1138 0.0 0
M  V30 7 C 3.4882 2.4437 0.0 0 CFG=2
M  V30 8 C 4.7298 0.2364 0.0 0
M  V30 9 C 4.6707 3.232 0.0 0 CFG=1
M  V30 10 C 3.4291 3.9809 0.0 0
M  V30 11 C 5.9123 1.0248 0.0 0
M  V30 12 C 4.6116 4.7692 0.0 0
M  V30 13 C 5.8531 2.562 0.0 0 CFG=1
M  V30 14 O 3.2714 5.5575 0.0 0
M  V30 15 C 5.794 5.5575 0.0 0
M  V30 16 C 7.0356 3.3503 0.0 0 CFG=1
M  V30 17 C 6.9765 4.8875 0.0 0 CFG=1
M  V30 18 C 9.5188 3.4094 0.0 0
M  V30 19 C 8.159 5.6758 0.0 0 CFG=1
M  V30 20 C 6.9174 6.4247 0.0 0
M  V30 21 C 9.4597 4.9466 0.0 0
M  V30 22 O 9.5385 6.1093 0.0 0
M  V30 23 C 8.0998 7.213 0.0 0
M  V30 24 O 6.7597 8.0013 0.0 0
M  V30 25 C 9.2823 8.0013 0.0 0
M  V30 26 O 9.2232 9.5385 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 7 10 CFG=1
M  V30 10 1 8 11
M  V30 11 1 9 12 CFG=1
M  V30 12 1 9 13
M  V30 13 2 12 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 15 17
M  V30 17 1 16 18 CFG=1
M  V30 18 1 17 19
M  V30 19 1 17 20 CFG=1
M  V30 20 1 18 21
M  V30 21 1 19 22 CFG=3
M  V30 22 1 19 23
M  V30 23 2 23 24
M  V30 24 1 23 25
M  V30 25 1 25 26
M  V30 26 1 6 7
M  V30 27 1 13 11 CFG=3
M  V30 28 1 16 17
M  V30 29 1 19 21
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(6 7 9 13 16 17 19)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000787A1-20220106-C00001

>  <Row No>
770

$$$$
US20220000789A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 6 0 0 0
M  V30 BEGIN ATOM
M  V30 1 P 0.0 0.0 0.0 0
M  V30 2 C -4.2339 0.3024 0.0 0
M  V30 3 C -5.7334 0.3402 0.0 0
M  V30 4 C -2.6966 0.3402 0.0 0
M  V30 5 A -7.3464 0.378 0.0 0
M  V30 6 C -1.2727 0.378 0.0 0
M  V30 7 C 2.0161 0.3024 0.0 0
M  V30 8 C 0.5166 0.3402 0.0 0
M  V30 9 C 3.44 0.3402 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 3
M  V30 2 1 2 4
M  V30 3 1 3 5
M  V30 4 1 4 6
M  V30 5 1 7 8
M  V30 6 1 7 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000789A1-20220106-C00001

>  <Row No>
771

$$$$
US20220000789A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 6 0 0 0
M  V30 BEGIN ATOM
M  V30 1 P 0.0 0.0 0.0 0
M  V30 2 C -4.2339 0.3024 0.0 0
M  V30 3 C -5.7334 0.3402 0.0 0
M  V30 4 C -2.6966 0.3402 0.0 0
M  V30 5 A -7.3464 0.378 0.0 0
M  V30 6 C -1.2727 0.378 0.0 0
M  V30 7 C 2.0161 0.3024 0.0 0
M  V30 8 C 0.5166 0.3402 0.0 0
M  V30 9 C 3.44 0.3402 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 3
M  V30 2 1 2 4
M  V30 3 1 3 5
M  V30 4 1 4 6
M  V30 5 1 7 8
M  V30 6 1 7 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000789A1-20220106-C00002

>  <Row No>
772

$$$$
US20220000789A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 6 0 0 0
M  V30 BEGIN ATOM
M  V30 1 P 0.0 0.0 0.0 0
M  V30 2 C -4.2339 0.3024 0.0 0
M  V30 3 C -5.7334 0.3402 0.0 0
M  V30 4 C -2.6966 0.3402 0.0 0
M  V30 5 A -7.3464 0.378 0.0 0
M  V30 6 C -1.2727 0.378 0.0 0
M  V30 7 C 2.0161 0.3024 0.0 0
M  V30 8 C 0.5166 0.3402 0.0 0
M  V30 9 C 3.44 0.3402 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 3
M  V30 2 1 2 4
M  V30 3 1 3 5
M  V30 4 1 4 6
M  V30 5 1 7 8
M  V30 6 1 7 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000789A1-20220106-C00003

>  <Row No>
773

$$$$
US20220000789A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 14 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C 0.7246 -1.268 0.0 0
M  V30 3 C 0.7246 1.3405 0.0 0
M  V30 4 C -1.5458 0.0362 0.0 0
M  V30 5 C 2.1979 -1.2318 0.0 0
M  V30 6 C 2.1979 1.3767 0.0 0
M  V30 7 C -3.0916 0.0724 0.0 0
M  V30 8 C -1.582 1.582 0.0 0
M  V30 9 C -1.582 -1.4371 0.0 0
M  V30 10 C 2.9225 0.1086 0.0 0
M  V30 11 C 4.3959 0.1449 0.0 0
M  V30 12 C 5.8693 0.1811 0.0 0
M  V30 13 C 4.2872 1.6907 0.0 0
M  V30 14 C 4.4321 -1.3284 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 2 3 6
M  V30 6 1 4 7
M  V30 7 1 4 8
M  V30 8 1 4 9
M  V30 9 2 5 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 1 6 10
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000789A1-20220106-C00004

>  <Row No>
774

$$$$
US20220000789A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C 0.8461 -1.1846 0.0 0
M  V30 3 C 0.8461 1.2571 0.0 0
M  V30 4 C -1.5472 0.0362 0.0 0
M  V30 5 C 2.2483 -0.6769 0.0 0
M  V30 6 C 2.2483 0.8219 0.0 0
M  V30 7 C -1.5835 1.5835 0.0 0
M  V30 8 C -1.5835 -1.4384 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 2 2 5
M  V30 5 2 3 6
M  V30 6 1 4 7
M  V30 7 1 4 8
M  V30 8 1 5 6
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000789A1-20220106-C00006

>  <Row No>
775

$$$$
US20220000789A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 N 1.4295 0.5175 0.0 0
M  V30 3 N -0.0369 -1.5034 0.0 0
M  V30 4 C 2.2922 -0.6901 0.0 0
M  V30 5 C 1.3925 -1.9471 0.0 0
M  V30 6 C -1.3186 -2.3661 0.0 0
M  V30 7 C 3.7957 -0.6531 0.0 0
M  V30 8 C -2.2552 -1.2447 0.0 0
M  V30 9 C -0.4559 -3.4136 0.0 0
M  V30 10 C 3.7587 0.9242 0.0 0
M  V30 11 C 3.7587 -2.1566 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 1 7 10
M  V30 10 1 7 11
M  V30 11 2 4 5
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000789A1-20220106-C00007

>  <Row No>
776

$$$$
US20220000789A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 9 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.4368 -1.4077 0.0 0
M  V30 3 N -0.4854 -2.597 0.0 0
M  V30 4 C 1.8446 -1.8446 0.0 0
M  V30 5 C -2.0387 -2.5606 0.0 0
M  V30 6 C 0.364 -3.7863 0.0 0
M  V30 7 C 1.8082 -3.3251 0.0 0
M  V30 8 C -2.0751 -1.0072 0.0 0
M  V30 9 C -2.0751 -4.0411 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 1 6 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000789A1-20220106-C00008

>  <Row No>
777

$$$$
US20220000789A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.0349 1.4906 0.0 0
M  V30 3 C 1.3742 0.4192 0.0 0
M  V30 4 C -1.479 0.2096 0.0 0
M  V30 5 C 0.5473 -1.3043 0.0 0
M  V30 6 C -2.3757 -0.92 0.0 0
M  V30 7 C -0.3493 -2.4339 0.0 0
M  V30 8 N -1.8284 -2.2243 0.0 0
M  V30 9 C -2.7251 -3.354 0.0 0
M  V30 10 C -4.1342 -2.2942 0.0 0
M  V30 11 C -1.3858 -4.3439 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 9 11
M  V30 11 1 7 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000789A1-20220106-C00009

>  <Row No>
778

$$$$
US20220000789A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3167 0.761 0.0 0
M  V30 3 C 1.2442 0.761 0.0 0
M  V30 4 C -2.6334 0.0724 0.0 0
M  V30 5 C -1.3529 2.271 0.0 0
M  V30 6 C 1.2079 2.271 0.0 0
M  V30 7 C -3.5877 1.3891 0.0 0
M  V30 8 C -1.7515 -1.1717 0.0 0
M  V30 9 C -0.1087 3.032 0.0 0
M  V30 10 O 5.7983 0.2899 0.0 0
M  V30 11 C 4.4816 1.0509 0.0 0
M  V30 12 C 7.0426 1.0509 0.0 0
M  V30 13 C 4.4454 2.5609 0.0 0
M  V30 14 C 7.0063 2.5609 0.0 0
M  V30 15 C 3.1287 3.3219 0.0 0
M  V30 16 C 5.6896 3.3219 0.0 0
M  V30 17 C 3.8172 4.6387 0.0 0
M  V30 18 C 2.3676 2.0777 0.0 0
M  V30 19 O 12.1766 0.2899 0.0 0
M  V30 20 C 10.8599 1.0509 0.0 0
M  V30 21 C 13.4208 1.0509 0.0 0
M  V30 22 C 10.8236 2.5609 0.0 0
M  V30 23 C 13.3846 2.5609 0.0 0
M  V30 24 C 12.0679 3.3219 0.0 0
M  V30 25 C 12.0316 4.8319 0.0 0
M  V30 26 C 10.5216 4.8682 0.0 0
M  V30 27 C 13.4691 4.8682 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 10 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 1 12 14
M  V30 13 1 13 15
M  V30 14 1 13 16
M  V30 15 1 15 17
M  V30 16 1 15 18
M  V30 17 1 19 20
M  V30 18 1 19 21
M  V30 19 1 20 22
M  V30 20 1 21 23
M  V30 21 1 22 24
M  V30 22 1 24 25
M  V30 23 1 25 26
M  V30 24 1 25 27
M  V30 25 1 6 9
M  V30 26 1 14 16
M  V30 27 1 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000789A1-20220106-C00010

>  <Row No>
779

$$$$
US20220000789A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 7 7 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -1.3438 0.8018 0.0 0
M  V30 3 C 0.35 -1.4229 0.0 0
M  V30 4 C 1.4229 0.4178 0.0 0
M  V30 5 C -0.6098 2.1456 0.0 0
M  V30 6 C -2.1456 -0.4743 0.0 0
M  V30 7 C 1.773 -1.005 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 7
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00035001.cdx

>  <name>
US20220000789A1-20220106-C00011

>  <Row No>
780

$$$$
US20220000789A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.0349 1.4906 0.0 0
M  V30 3 C 1.3742 0.4192 0.0 0
M  V30 4 C -1.479 0.2096 0.0 0
M  V30 5 C 0.5473 -1.3043 0.0 0
M  V30 6 C -2.3757 -0.92 0.0 0
M  V30 7 C -0.3493 -2.4339 0.0 0
M  V30 8 N -1.8284 -2.2243 0.0 0
M  V30 9 C -2.7251 -3.354 0.0 0
M  V30 10 C -4.1342 -2.2942 0.0 0
M  V30 11 C -1.3858 -4.3439 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 9 11
M  V30 11 1 7 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000789A1-20220106-C00012

>  <Row No>
781

$$$$
US20220000789A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C -1.2877 -0.7206 0.0 0
M  V30 3 C -0.059 1.4886 0.0 0
M  V30 4 C 1.2286 -0.6852 0.0 0
M  V30 5 C -2.1856 0.7915 0.0 0
M  V30 6 C -0.4607 -2.162 0.0 0
M  V30 7 C 1.1578 2.2565 0.0 0
M  V30 8 C 2.4455 0.0827 0.0 0
M  V30 9 N 2.3865 1.5713 0.0 0
M  V30 10 C 3.6033 2.3274 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 1 8 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000789A1-20220106-C00013

>  <Row No>
782

$$$$
US20220000789A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 13 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.2224 -1.4048 0.0 0
M  V30 3 C -1.475 -0.2224 0.0 0
M  V30 4 C -1.2526 -1.6272 0.0 0
M  V30 5 C -2.7511 -1.4633 0.0 0
M  V30 6 C -0.6555 -2.915 0.0 0
M  V30 7 C -3.6174 -2.634 0.0 0
M  V30 8 C -1.5219 -4.0857 0.0 0
M  V30 9 N -3.0204 -3.9218 0.0 0
M  V30 10 C -3.8867 -5.0925 0.0 0
M  V30 11 C -5.3383 -4.074 0.0 0
M  V30 12 C -2.5052 -6.0408 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 10 12
M  V30 12 1 3 4
M  V30 13 1 8 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00038001.cdx

>  <name>
US20220000789A1-20220106-C00014

>  <Row No>
783

$$$$
US20220000789A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 14 15 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0352 -1.4442 0.0 0
M  V30 3 O -1.2681 -2.3249 0.0 0
M  V30 4 C 1.1272 -2.2779 0.0 0
M  V30 5 C -0.8454 -3.6518 0.0 0
M  V30 6 C 0.634 -3.6518 0.0 0
M  V30 7 C -2.3484 -3.4639 0.0 0
M  V30 8 C -0.27 -4.9669 0.0 0
M  V30 9 C -3.2408 -4.6264 0.0 0
M  V30 10 C -1.1624 -6.1294 0.0 0
M  V30 11 N -2.6654 -5.9415 0.0 0
M  V30 12 C -3.5578 -7.104 0.0 0
M  V30 13 C -5.0021 -6.0472 0.0 0
M  V30 14 C -2.184 -8.0903 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 1 12 14
M  V30 14 1 5 6
M  V30 15 1 10 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00039001.cdx

>  <name>
US20220000789A1-20220106-C00015

>  <Row No>
784

$$$$
US20220000789A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 N 1.2815 -0.3858 0.0 0
M  V30 3 N -0.8681 -1.0885 0.0 0
M  V30 4 C 1.2401 -1.7362 0.0 0
M  V30 5 C -0.0688 -2.1634 0.0 0
M  V30 6 C -2.2874 -1.0472 0.0 0
M  V30 7 C -3.0315 0.1929 0.0 0
M  V30 8 C -3.0315 -2.2047 0.0 0
M  V30 9 C -4.4646 0.2342 0.0 0
M  V30 10 C -4.4646 -2.1634 0.0 0
M  V30 11 C -5.2087 -0.9232 0.0 0
M  V30 12 C -6.9725 -0.8819 0.0 0
M  V30 13 N -7.8544 -2.3701 0.0 0
M  V30 14 ? -7.0138 0.5511 0.0 0
M  V30 15 ? -8.2816 -0.2342 0.0 0
M  V30 16 C -7.3032 -3.7067 0.0 0
M  V30 17 C -8.3229 -4.6437 0.0 0
M  V30 18 C -6.3662 -2.687 0.0 0
M  V30 19 C 1.3228 -2.7559 0.0 0
M  V30 20 C 2.9075 -1.9429 0.0 0
M  V30 21 C -0.3307 -1.0059 0.0 0
M  V30 22 ? 2.0118 -4.0925 0.0 0
M  V30 23 ? 0.4547 -4.0788 0.0 0
M  V30 24 C 4.3406 -1.9016 0.0 0
M  V30 25 C 5.5118 -2.3149 0.0 0
M  V30 26 C 6.9174 -2.7008 0.0 0
M  V30 27 C -4.0788 -0.8819 0.0 0
M  V30 28 C 5.0709 -1.9842 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 6 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 1 12 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 16 17
M  V30 17 1 16 18
M  V30 18 1 19 20
M  V30 19 1 19 21
M  V30 20 1 19 22
M  V30 21 1 19 23
M  V30 22 1 20 24
M  V30 23 1 25 26
M  V30 24 2 4 5
M  V30 25 1 10 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00041001.cdx

>  <name>
US20220000789A1-20220106-C00017

>  <Row No>
785

$$$$
US20220000789A1-20220106-C00018
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.7006 -0.744 0.0 0
M  V30 3 C 1.4615 0.0398 0.0 0
M  V30 4 C -3.109 0.0797 0.0 0
M  V30 5 ? -1.0097 -1.9265 0.0 0
M  V30 6 ? -2.4712 -1.9265 0.0 0
M  V30 7 N -3.1622 1.5412 0.0 0
M  V30 8 C -4.5041 -0.3321 0.0 0
M  V30 9 N -4.5572 2.0195 0.0 0
M  V30 10 N -5.3677 0.8503 0.0 0
M  V30 11 C -6.8292 0.8901 0.0 0
M  V30 12 C -7.5999 2.1524 0.0 0
M  V30 13 C -7.5999 -0.2923 0.0 0
M  V30 14 C -9.0614 2.1922 0.0 0
M  V30 15 C -9.0614 -0.2524 0.0 0
M  V30 16 C -9.832 1.0097 0.0 0
M  V30 17 C -11.1208 1.0496 0.0 0
M  V30 18 N -12.0243 -0.3055 0.0 0
M  V30 19 C -11.2935 -1.6608 0.0 0
M  V30 20 C -12.5557 -2.3517 0.0 0
M  V30 21 C -10.111 -0.8901 0.0 0
M  V30 22 C -8.9285 1.3818 0.0 0
M  V30 23 C -10.4432 2.8831 0.0 0
M  V30 24 C 2.3384 0.0 0.0 0
M  V30 25 C 3.7202 0.0398 0.0 0
M  V30 26 C 1.8069 0.3188 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 2 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 7 9
M  V30 9 1 8 10
M  V30 10 1 10 11
M  V30 11 2 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 2 14 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 19 21
M  V30 21 1 22 23
M  V30 22 1 24 25
M  V30 23 1 9 10
M  V30 24 1 15 16
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00046001.cdx

>  <name>
US20220000789A1-20220106-C00018

>  <Row No>
786

$$$$
US20220000789A1-20220106-C00019
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 N 1.3862 -0.458 0.0 0
M  V30 3 N -0.9282 -1.1692 0.0 0
M  V30 4 C 1.326 -1.9287 0.0 0
M  V30 5 C -2.4711 -1.1331 0.0 0
M  V30 6 C -0.1084 -2.3626 0.0 0
M  V30 7 C 2.5917 -2.652 0.0 0
M  V30 8 C -3.2547 -2.3988 0.0 0
M  V30 9 C -3.2547 0.2049 0.0 0
M  V30 10 C 3.8574 -1.8684 0.0 0
M  V30 11 ? 1.8081 -3.9177 0.0 0
M  V30 12 ? 3.315 -3.9177 0.0 0
M  V30 13 C -4.7977 -2.3626 0.0 0
M  V30 14 C -4.7977 0.241 0.0 0
M  V30 15 C -5.5812 -1.0246 0.0 0
M  V30 16 C -7.1242 -0.9884 0.0 0
M  V30 17 N -7.9077 -2.2542 0.0 0
M  V30 18 C -7.1724 -3.5199 0.0 0
M  V30 19 C -5.9067 -2.7363 0.0 0
M  V30 20 C -8.5105 -4.2432 0.0 0
M  V30 21 C 6.2683 -1.6394 0.0 0
M  V30 22 C 7.739 -1.6032 0.0 0
M  V30 23 C -4.9182 -0.5786 0.0 0
M  V30 24 C -6.2563 0.2049 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 1 7 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 1 8 13
M  V30 13 2 9 14
M  V30 14 2 13 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 21 22
M  V30 21 1 23 24
M  V30 22 2 4 6
M  V30 23 1 14 15
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00047001.cdx

>  <name>
US20220000789A1-20220106-C00019

>  <Row No>
787

$$$$
US20220000789A1-20220106-C00020
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 19 18 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 N 1.3963 -0.4613 0.0 0
M  V30 3 N -0.9349 -1.1777 0.0 0
M  V30 4 C 1.3356 -1.9427 0.0 0
M  V30 5 C -0.1092 -2.3798 0.0 0
M  V30 6 C -2.489 -1.1413 0.0 0
M  V30 7 C 2.6105 -2.6712 0.0 0
M  V30 8 N -3.2783 -2.4162 0.0 0
M  V30 9 ? -2.5255 0.4128 0.0 0
M  V30 10 ? -3.9946 -0.7042 0.0 0
M  V30 11 C 3.8854 -1.8819 0.0 0
M  V30 12 ? 1.8212 -3.9461 0.0 0
M  V30 13 ? 3.339 -3.9461 0.0 0
M  V30 14 C -2.5498 -3.6911 0.0 0
M  V30 15 C 5.3667 -1.8455 0.0 0
M  V30 16 C -1.2749 -2.9019 0.0 0
M  V30 17 C -3.8975 -4.4196 0.0 0
M  V30 18 C 8.0622 -2.1369 0.0 0
M  V30 19 C 9.5435 -2.1005 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 1 7 13
M  V30 13 1 8 14
M  V30 14 1 11 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 17 1 18 19
M  V30 18 2 4 5
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00048001.cdx

>  <name>
US20220000789A1-20220106-C00020

>  <Row No>
788

$$$$
US20220000789A1-20220106-C00021
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 19 18 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 N 1.3884 -0.4423 0.0 0
M  V30 3 N -0.9461 -1.1672 0.0 0
M  V30 4 C 1.327 -1.9168 0.0 0
M  V30 5 C -0.1105 -2.3714 0.0 0
M  V30 6 C -2.4943 -1.1304 0.0 0
M  V30 7 C 2.5926 -2.6171 0.0 0
M  V30 8 N -3.2683 -2.396 0.0 0
M  V30 9 ? -2.5311 0.4177 0.0 0
M  V30 10 ? -3.981 -0.7126 0.0 0
M  V30 11 C 3.8581 -1.843 0.0 0
M  V30 12 ? 1.8185 -3.8827 0.0 0
M  V30 13 ? 3.2929 -3.8827 0.0 0
M  V30 14 C -2.6663 -3.9441 0.0 0
M  V30 15 C 5.3326 -1.8062 0.0 0
M  V30 16 C -1.4007 -3.1701 0.0 0
M  V30 17 C -4.0056 -4.6445 0.0 0
M  V30 18 C 8.0604 -1.9659 0.0 0
M  V30 19 C 9.5348 -1.929 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 6 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 7 11
M  V30 11 1 7 12
M  V30 12 1 7 13
M  V30 13 1 8 14
M  V30 14 1 11 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 17 1 18 19
M  V30 18 2 4 5
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00049001.cdx

>  <name>
US20220000789A1-20220106-C00021

>  <Row No>
789

$$$$
US20220000789A1-20220106-C00022
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00050001.cdx

>  <name>
US20220000789A1-20220106-C00022

>  <Row No>
790

$$$$
US20220000789A1-20220106-C00023
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 15 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 N 1.4474 -0.205 0.0 0
M  V30 3 N -0.7357 -1.3026 0.0 0
M  V30 4 C 1.6524 -1.6524 0.0 0
M  V30 5 C 0.2894 -2.3279 0.0 0
M  V30 6 C -2.2796 -1.2664 0.0 0
M  V30 7 C 2.9551 -2.3158 0.0 0
M  V30 8 C -3.8235 -1.2302 0.0 0
M  V30 9 C 4.4266 -2.2796 0.0 0
M  V30 10 N -4.6075 -2.4967 0.0 0
M  V30 11 ? -3.8597 0.3136 0.0 0
M  V30 12 ? -5.3192 -0.796 0.0 0
M  V30 13 C -4.2457 -3.92 0.0 0
M  V30 14 C -2.8224 -3.4858 0.0 0
M  V30 15 C -5.7413 -4.2819 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 13 14
M  V30 14 1 13 15
M  V30 15 2 4 5
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00056001.cdx

>  <name>
US20220000789A1-20220106-C00023

>  <Row No>
791

$$$$
US20220000789A1-20220106-C00024
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 N -1.4841 0.2754 0.0 0
M  V30 3 C 0.1836 -1.3923 0.0 0
M  V30 4 C -2.2032 -0.9639 0.0 0 CFG=2
M  V30 5 N -1.1475 -2.0196 0.0 0
M  V30 6 C 1.4229 -2.0196 0.0 0
M  V30 7 C -3.7026 -0.918 0.0 0
M  V30 8 C 2.8305 -1.9737 0.0 0
M  V30 9 C -4.483 -2.1267 0.0 0
M  V30 10 C -4.483 0.3825 0.0 0
M  V30 11 C -5.9824 -2.0808 0.0 0
M  V30 12 C -5.9824 0.4284 0.0 0
M  V30 13 C -6.7627 -0.7803 0.0 0
M  V30 14 C -8.2622 -0.7344 0.0 0
M  V30 15 N -9.0425 -1.9431 0.0 0
M  V30 16 ? -8.3081 0.765 0.0 0
M  V30 17 ? -9.7157 -0.306 0.0 0
M  V30 18 C -8.7059 -3.3048 0.0 0
M  V30 19 C -7.3441 -2.8764 0.0 0
M  V30 20 C -10.1594 -3.6414 0.0 0
M  V30 21 C -6.1201 -0.3672 0.0 0
M  V30 22 C -7.1299 1.5912 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7 CFG=3
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 7 10
M  V30 10 1 9 11
M  V30 11 2 10 12
M  V30 12 2 11 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 21 22
M  V30 21 1 4 5
M  V30 22 1 12 13
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 4)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00057001.cdx

>  <name>
US20220000789A1-20220106-C00024

>  <Row No>
792

$$$$
US20220000789A1-20220106-C00026
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.7944 -1.2358 0.0 0
M  V30 3 C 1.4376 0.0378 0.0 0
M  V30 4 C -2.3077 -1.198 0.0 0
M  V30 5 C 2.1564 1.3493 0.0 0
M  V30 6 N -3.1022 -2.4338 0.0 0
M  V30 7 ? -2.3455 0.3152 0.0 0
M  V30 8 ? -3.7706 -0.7692 0.0 0
M  V30 9 N 3.594 1.3871 0.0 0
M  V30 10 C -2.3834 -3.6697 0.0 0
M  V30 11 N 4.2372 2.7365 0.0 0
M  V30 12 C 4.6281 0.3152 0.0 0
M  V30 13 C -1.1475 -2.8752 0.0 0
M  V30 14 C -3.6949 -4.3885 0.0 0
M  V30 15 C -1.6646 -4.9055 0.0 0
M  V30 16 N 5.6622 2.5347 0.0 0
M  V30 17 C 5.8639 1.1097 0.0 0
M  V30 18 C 5.8513 0.0 0.0 0
M  V30 19 C 5.019 1.3619 0.0 0
M  V30 20 C 7.289 0.0378 0.0 0
M  V30 21 ? 5.9648 -1.3997 0.0 0
M  V30 22 ? 4.7794 -0.9962 0.0 0
M  V30 23 C 2.0177 0.6053 0.0 0
M  V30 24 C 0.7062 2.2194 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 1 10 15
M  V30 15 2 11 16
M  V30 16 2 12 17
M  V30 17 1 18 19
M  V30 18 1 18 20
M  V30 19 1 18 21
M  V30 20 1 18 22
M  V30 21 1 23 24
M  V30 22 1 16 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00059001.cdx

>  <name>
US20220000789A1-20220106-C00026

>  <Row No>
793

$$$$
US20220000789A1-20220106-C00027
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.7986 -1.2422 0.0 0
M  V30 3 C 1.4451 0.038 0.0 0
M  V30 4 C -2.3197 -1.2042 0.0 0
M  V30 5 C 2.1676 1.3563 0.0 0
M  V30 6 N -3.1184 -2.4465 0.0 0
M  V30 7 ? -2.3578 0.3169 0.0 0
M  V30 8 ? -3.7902 -0.7732 0.0 0
M  V30 9 N 3.6127 1.3944 0.0 0
M  V30 10 C -2.7634 -3.8409 0.0 0
M  V30 11 N 4.2592 2.7507 0.0 0
M  V30 12 C 4.6522 0.3169 0.0 0
M  V30 13 C -1.369 -3.4099 0.0 0
M  V30 14 C -4.2339 -4.1958 0.0 0
M  V30 15 C -2.4085 -5.2353 0.0 0
M  V30 16 N 5.6917 2.5479 0.0 0
M  V30 17 C 5.8945 1.1155 0.0 0
M  V30 18 C 7.1368 0.3929 0.0 0
M  V30 19 C 8.5819 0.4309 0.0 0
M  V30 20 ? 7.2509 -1.0141 0.0 0
M  V30 21 ? 6.0593 -0.6084 0.0 0
M  V30 22 C 2.0282 0.6084 0.0 0
M  V30 23 C 0.7098 2.231 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 1 10 15
M  V30 15 2 11 16
M  V30 16 2 12 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 22 23
M  V30 22 1 16 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00060001.cdx

>  <name>
US20220000789A1-20220106-C00027

>  <Row No>
794

$$$$
US20220000789A1-20220106-C00028
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.7935 -1.2343 0.0 0
M  V30 3 C 1.4359 0.0377 0.0 0
M  V30 4 C -2.305 -1.1965 0.0 0
M  V30 5 C 2.1538 1.3477 0.0 0
M  V30 6 N -3.0985 -2.4309 0.0 0
M  V30 7 ? -2.3428 0.3148 0.0 0
M  V30 8 ? -3.7661 -0.7683 0.0 0
M  V30 9 N 3.5897 1.3855 0.0 0
M  V30 10 C -2.3805 -3.6653 0.0 0
M  V30 11 N 4.2321 2.7332 0.0 0
M  V30 12 C 4.6226 0.3148 0.0 0
M  V30 13 C -1.1462 -2.8718 0.0 0
M  V30 14 C -3.6905 -4.3833 0.0 0
M  V30 15 N 5.6554 2.5317 0.0 0
M  V30 16 C 5.857 1.1084 0.0 0
M  V30 17 N 7.1543 0.0 0.0 0
M  V30 18 C 5.6428 0.0377 0.0 0
M  V30 19 C 7.8723 -1.2343 0.0 0
M  V30 20 C 7.8723 1.3099 0.0 0
M  V30 21 C 4.2573 1.1336 0.0 0
M  V30 22 ? 5.7562 -1.3603 0.0 0
M  V30 23 ? 4.5722 -0.9572 0.0 0
M  V30 24 C 9.3082 -1.1965 0.0 0
M  V30 25 C 9.3082 1.3477 0.0 0
M  V30 26 C 10.0262 0.1133 0.0 0
M  V30 27 C 2.0153 0.6045 0.0 0
M  V30 28 C 0.7053 2.2168 0.0 0
M  V30 29 C 8.4643 0.6045 0.0 0
M  V30 30 C 8.817 2.0657 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 2 11 15
M  V30 15 2 12 16
M  V30 16 1 17 18
M  V30 17 1 17 19
M  V30 18 1 17 20
M  V30 19 1 18 21
M  V30 20 1 18 22
M  V30 21 1 18 23
M  V30 22 1 19 24
M  V30 23 1 20 25
M  V30 24 1 24 26
M  V30 25 1 27 28
M  V30 26 1 29 30
M  V30 27 1 15 16
M  V30 28 1 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00065001.cdx

>  <name>
US20220000789A1-20220106-C00028

>  <Row No>
795

$$$$
US20220000789A1-20220106-C00029
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.8025 -1.2483 0.0 0
M  V30 3 C 1.4521 0.0382 0.0 0
M  V30 4 C -2.3311 -1.2101 0.0 0
M  V30 5 C 2.1782 1.363 0.0 0
M  V30 6 N -3.1336 -2.4585 0.0 0
M  V30 7 ? -2.3693 0.3184 0.0 0
M  V30 8 ? -3.8087 -0.777 0.0 0
M  V30 9 N 3.6304 1.4012 0.0 0
M  V30 10 C -2.7769 -3.8597 0.0 0
M  V30 11 N 4.2801 2.7642 0.0 0
M  V30 12 C 4.675 0.3184 0.0 0
M  V30 13 C -1.3757 -3.4266 0.0 0
M  V30 14 C -4.2546 -4.2164 0.0 0
M  V30 15 C -2.4203 -5.2609 0.0 0
M  V30 16 N 5.7195 2.5604 0.0 0
M  V30 17 C 5.9233 1.1209 0.0 0
M  V30 18 C 7.2354 0.5095 0.0 0
M  V30 19 N 8.6876 0.5477 0.0 0
M  V30 20 ? 7.35 -0.9044 0.0 0
M  V30 21 ? 6.1526 -0.4967 0.0 0
M  V30 22 C 9.4136 -0.7006 0.0 0
M  V30 23 C 9.4136 1.8725 0.0 0
M  V30 24 C 10.8658 -0.6623 0.0 0
M  V30 25 C 10.8658 1.9107 0.0 0
M  V30 26 C 11.5919 0.6623 0.0 0
M  V30 27 C 10.1907 1.1209 0.0 0
M  V30 28 C 10.5474 2.5986 0.0 0
M  V30 29 C 2.0381 0.6114 0.0 0
M  V30 30 C 0.7133 2.2419 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7
M  V30 7 1 4 8
M  V30 8 1 5 9
M  V30 9 1 6 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 1 10 15
M  V30 15 2 11 16
M  V30 16 2 12 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 19 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 1 24 26
M  V30 26 1 27 28
M  V30 27 1 29 30
M  V30 28 1 16 17
M  V30 29 1 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00066001.cdx

>  <name>
US20220000789A1-20220106-C00029

>  <Row No>
796

$$$$
US20220000789A1-20220106-C00030
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3943 -0.5839 0.0 0 CFG=2
M  V30 3 C 1.1678 -0.8342 0.0 0
M  V30 4 O -2.6336 0.3217 0.0 0
M  V30 5 C -1.5849 -2.0259 0.0 0
M  V30 6 C 0.9772 -2.2761 0.0 0
M  V30 7 C -4.0279 -0.2621 0.0 0
M  V30 8 C -0.4171 -2.8601 0.0 0
M  V30 9 C -5.2673 0.6435 0.0 0
M  V30 10 N -5.3031 2.1689 0.0 0
M  V30 11 C -6.7212 0.2145 0.0 0
M  V30 12 N -6.757 2.6694 0.0 0
M  V30 13 N -7.6269 1.4538 0.0 0
M  V30 14 C -9.1523 1.4896 0.0 0
M  V30 15 C -9.915 0.2383 0.0 0
M  V30 16 C -9.915 2.8124 0.0 0
M  V30 17 C -11.4404 0.274 0.0 0
M  V30 18 C -11.4404 2.8481 0.0 0
M  V30 19 C -12.215 1.5968 0.0 0
M  V30 20 C -13.7404 1.6326 0.0 0
M  V30 21 N -14.515 0.3813 0.0 0
M  V30 22 C -14.5508 -1.0725 0.0 0
M  V30 23 C -16.0762 -1.0367 0.0 0
M  V30 24 C -13.0969 -1.0367 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4 CFG=1
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 9 11
M  V30 11 2 10 12
M  V30 12 1 11 13
M  V30 13 1 13 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 2 17 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 22 24
M  V30 24 1 6 8
M  V30 25 1 12 13
M  V30 26 1 18 19
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00069001.cdx

>  <name>
US20220000789A1-20220106-C00030

>  <Row No>
797

$$$$
US20220000789A1-20220106-C00031
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 30 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 1.451 0.0356 0.0 0
M  V30 3 O 0.7136 1.3202 0.0 0
M  V30 4 C -0.1903 -1.4391 0.0 0
M  V30 5 C -1.2369 0.9039 0.0 0
M  V30 6 C -1.5818 -2.0219 0.0 0
M  V30 7 C -2.6285 0.3211 0.0 0
M  V30 8 N -2.8188 -1.118 0.0 0
M  V30 9 C -4.2104 -1.7008 0.0 0
M  V30 10 C -5.4473 -0.7968 0.0 0
M  V30 11 N -5.483 0.7255 0.0 0
M  V30 12 C -6.8983 -1.225 0.0 0
M  V30 13 N -6.934 1.225 0.0 0
M  V30 14 N -7.8023 0.0118 0.0 0
M  V30 15 C -9.3247 0.0475 0.0 0
M  V30 16 C -10.0859 -1.2012 0.0 0
M  V30 17 O -11.6083 -1.1655 0.0 0
M  V30 18 C -12.3695 -2.4144 0.0 0
M  V30 19 C -13.8919 -2.3787 0.0 0
M  V30 20 O -14.665 -3.6276 0.0 0
M  V30 21 C -16.1874 -3.5919 0.0 0
M  V30 22 C -16.9605 -4.8407 0.0 0
M  V30 23 O -18.4829 -4.805 0.0 0
M  V30 24 C -19.2441 -6.0539 0.0 0
M  V30 25 C -20.7665 -6.0182 0.0 0
M  V30 26 N -21.5396 -7.2671 0.0 0
M  V30 27 C -23.062 -7.2314 0.0 0
M  V30 28 C -23.0977 -5.709 0.0 0
M  V30 29 C -23.0977 -8.6824 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 2 10 12
M  V30 12 2 11 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 26 1 26 27
M  V30 27 1 27 28
M  V30 28 1 27 29
M  V30 29 1 7 8
M  V30 30 1 13 14
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00070001.cdx

>  <name>
US20220000789A1-20220106-C00031

>  <Row No>
798

$$$$
US20220000789A1-20220106-C00032
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 27 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.7274 1.3458 0.0 0
M  V30 3 C -1.5519 0.0363 0.0 0
M  V30 4 C 2.2067 1.3822 0.0 0
M  V30 5 C -2.3279 -1.2367 0.0 0
M  V30 6 O 2.9341 2.728 0.0 0
M  V30 7 O -3.8799 -1.2003 0.0 0
M  V30 8 C 4.4134 2.7644 0.0 0
M  V30 9 C -4.6559 -2.4734 0.0 0
M  V30 10 C 5.1409 4.1103 0.0 0
M  V30 11 C -6.2078 -2.437 0.0 0
M  V30 12 N 6.6201 4.1466 0.0 0
M  V30 13 N -6.9838 -3.7101 0.0 0
M  V30 14 N 7.4688 5.4076 0.0 0
M  V30 15 C 7.4688 2.9584 0.0 0
M  V30 16 C -8.5358 -3.6738 0.0 0
M  V30 17 N 8.8753 4.9711 0.0 0
M  V30 18 C 8.8753 3.4676 0.0 0
M  V30 19 C -8.5722 -2.1218 0.0 0
M  V30 20 C -8.5722 -5.153 0.0 0
M  V30 21 C 10.0635 2.6189 0.0 0
M  V30 22 C 9.8695 1.1518 0.0 0
M  V30 23 C 11.4094 3.2858 0.0 0
M  V30 24 C 11.0578 0.3031 0.0 0
M  V30 25 C 12.5976 2.437 0.0 0
M  V30 26 C 12.4036 0.9699 0.0 0
M  V30 27 N 13.5918 0.1212 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 15 18
M  V30 18 1 16 19
M  V30 19 1 16 20
M  V30 20 1 18 21
M  V30 21 2 21 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 2 23 25
M  V30 25 2 24 26
M  V30 26 1 26 27
M  V30 27 1 17 18
M  V30 28 1 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00071001.cdx

>  <name>
US20220000789A1-20220106-C00032

>  <Row No>
799

$$$$
US20220000789A1-20220106-C00033
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 N 1.3888 -0.431 0.0 0
M  V30 3 N -0.9099 -1.1733 0.0 0
M  V30 4 C 1.3529 -1.8917 0.0 0
M  V30 5 C -2.4424 -1.1374 0.0 0
M  V30 6 C -0.0718 -2.3466 0.0 0
M  V30 7 C -3.2206 -2.3945 0.0 0
M  V30 8 C -3.2206 0.1915 0.0 0
M  V30 9 C -4.7532 -2.3586 0.0 0
M  V30 10 C -4.7532 0.2274 0.0 0
M  V30 11 C -5.5194 -1.0296 0.0 0
M  V30 12 C -7.052 -0.9937 0.0 0
M  V30 13 N -7.8302 -2.2508 0.0 0
M  V30 14 C -9.3627 -2.2149 0.0 0
M  V30 15 C -9.3986 -0.6824 0.0 0
M  V30 16 C -9.3986 -3.6756 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 2 9 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 2 4 6
M  V30 17 1 10 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00072001.cdx

>  <name>
US20220000789A1-20220106-C00033

>  <Row No>
800

$$$$
US20220000789A1-20220106-C00034
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 18 19 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3823 -0.5789 0.0 0
M  V30 3 C -2.6111 0.319 0.0 0
M  V30 4 N -2.6466 1.8313 0.0 0
M  V30 5 C -4.0526 -0.1063 0.0 0
M  V30 6 N -4.088 2.3275 0.0 0
M  V30 7 N -4.9505 1.1224 0.0 0
M  V30 8 C -6.4629 1.1578 0.0 0
M  V30 9 C -7.2309 -0.0827 0.0 0
M  V30 10 C -7.2309 2.4693 0.0 0
M  V30 11 C -8.7432 -0.0472 0.0 0
M  V30 12 C -8.7432 2.5048 0.0 0
M  V30 13 C -9.5112 1.2642 0.0 0
M  V30 14 C -11.0235 1.2996 0.0 0
M  V30 15 N -11.7915 0.059 0.0 0
M  V30 16 C -13.3039 0.0945 0.0 0
M  V30 17 C -13.3393 1.6068 0.0 0
M  V30 18 C -13.3393 -1.3469 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 4 2 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 1 7 8
M  V30 8 2 8 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 2 10 12
M  V30 12 2 11 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 16 18
M  V30 18 1 6 7
M  V30 19 1 12 13
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00073001.cdx

>  <name>
US20220000789A1-20220106-C00034

>  <Row No>
801

$$$$
US20220000789A1-20220106-C00035
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 19 20 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.7664 -1.2574 0.0 0 CFG=2
M  V30 3 C 1.461 0.0359 0.0 0
M  V30 4 O -2.2994 -1.2215 0.0 0
M  V30 5 C -0.0479 -2.5149 0.0 0
M  V30 6 C 2.1916 -1.2215 0.0 0
M  V30 7 C -3.0658 0.1077 0.0 0
M  V30 8 C 1.4131 -2.479 0.0 0
M  V30 9 C -4.5988 0.1437 0.0 0
M  V30 10 C -5.3652 -1.1137 0.0 0
M  V30 11 C -5.3652 1.473 0.0 0
M  V30 12 C -6.8982 -1.0778 0.0 0
M  V30 13 C -6.8982 1.5089 0.0 0
M  V30 14 C -7.6646 0.2514 0.0 0
M  V30 15 C -9.1976 0.2874 0.0 0
M  V30 16 N -9.976 -0.97 0.0 0
M  V30 17 C -11.509 -0.9341 0.0 0
M  V30 18 C -11.5449 0.5988 0.0 0
M  V30 19 C -11.5449 -2.3952 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4 CFG=1
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 2 11 13
M  V30 13 2 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 17 19
M  V30 19 1 6 8
M  V30 20 1 13 14
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00074001.cdx

>  <name>
US20220000789A1-20220106-C00035

>  <Row No>
802

$$$$
US20220000789A1-20220106-C00036
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3126 0.7568 0.0 0 CFG=2
M  V30 3 C 1.2416 0.7568 0.0 0
M  V30 4 O -2.6252 0.0473 0.0 0
M  V30 5 C -1.348 2.2704 0.0 0
M  V30 6 C 1.2061 2.2704 0.0 0
M  V30 7 C -3.9378 0.8159 0.0 0
M  V30 8 C -0.1064 3.039 0.0 0
M  V30 9 C -5.2504 0.1064 0.0 0
M  V30 10 C -6.563 0.875 0.0 0
M  V30 11 N -6.5984 2.3887 0.0 0
M  V30 12 C -8.0057 0.4493 0.0 0
M  V30 13 N -8.0411 2.8853 0.0 0
M  V30 14 N -8.9044 1.6791 0.0 0
M  V30 15 C -10.418 1.7146 0.0 0
M  V30 16 C -11.1866 0.473 0.0 0
M  V30 17 C -11.1866 3.0272 0.0 0
M  V30 18 C -12.7003 0.5084 0.0 0
M  V30 19 C -12.7003 3.0627 0.0 0
M  V30 20 C -13.4689 1.821 0.0 0
M  V30 21 C -14.9826 1.8565 0.0 0
M  V30 22 N -15.7394 0.6149 0.0 0
M  V30 23 C -17.253 0.6503 0.0 0
M  V30 24 C -17.2885 2.164 0.0 0
M  V30 25 C -17.2885 -0.7922 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4 CFG=3
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 2 10 12
M  V30 12 2 11 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 2 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 23 25
M  V30 25 1 6 8
M  V30 26 1 13 14
M  V30 27 1 19 20
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00075001.cdx

>  <name>
US20220000789A1-20220106-C00036

>  <Row No>
803

$$$$
US20220000789A1-20220106-C00037
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3126 0.7568 0.0 0 CFG=2
M  V30 3 C 1.2416 0.7568 0.0 0
M  V30 4 O -2.6252 0.0473 0.0 0
M  V30 5 C -1.348 2.2704 0.0 0
M  V30 6 C 1.2061 2.2704 0.0 0
M  V30 7 C -3.9378 0.8159 0.0 0
M  V30 8 C -0.1064 3.039 0.0 0
M  V30 9 C -5.2504 0.1064 0.0 0
M  V30 10 N -6.563 0.875 0.0 0
M  V30 11 N -6.5984 2.3887 0.0 0
M  V30 12 C -8.0057 0.4493 0.0 0
M  V30 13 N -8.0411 2.8853 0.0 0
M  V30 14 C -8.9044 1.6791 0.0 0
M  V30 15 C -10.418 1.7146 0.0 0
M  V30 16 C -11.1866 0.473 0.0 0
M  V30 17 C -11.1866 3.0272 0.0 0
M  V30 18 C -12.7003 0.5084 0.0 0
M  V30 19 C -12.7003 3.0627 0.0 0
M  V30 20 C -13.4689 1.821 0.0 0
M  V30 21 C -14.9826 1.8565 0.0 0
M  V30 22 N -15.7394 0.6149 0.0 0
M  V30 23 C -17.253 0.6503 0.0 0
M  V30 24 C -17.2885 2.164 0.0 0
M  V30 25 C -17.2885 -0.7922 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4 CFG=3
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 10 12
M  V30 12 2 11 13
M  V30 13 2 12 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 2 18 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 23 25
M  V30 25 1 6 8
M  V30 26 1 13 14
M  V30 27 1 19 20
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00076001.cdx

>  <name>
US20220000789A1-20220106-C00037

>  <Row No>
804

$$$$
US20220000789A1-20220106-C00038
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3199 -0.7134 0.0 0
M  V30 3 C 1.2485 -0.7134 0.0 0
M  V30 4 O -2.6398 0.0475 0.0 0
M  V30 5 C -1.3556 -2.1642 0.0 0
M  V30 6 C 1.2129 -2.1642 0.0 0
M  V30 7 C -3.9598 -0.6659 0.0 0
M  V30 8 C -0.107 -2.8776 0.0 0
M  V30 9 C -5.2797 0.0951 0.0 0
M  V30 10 N -5.3154 1.6172 0.0 0
M  V30 11 C -6.7304 -0.3329 0.0 0
M  V30 12 N -6.7661 2.1166 0.0 0
M  V30 13 N -7.6342 0.9037 0.0 0
M  V30 14 C -9.1562 0.9394 0.0 0
M  V30 15 C -9.9292 -0.3091 0.0 0
M  V30 16 C -9.9292 2.2593 0.0 0
M  V30 17 C -11.4513 -0.2734 0.0 0
M  V30 18 C -11.4513 2.295 0.0 0
M  V30 19 C -12.2242 1.0464 0.0 0
M  V30 20 C -13.7463 1.0821 0.0 0
M  V30 21 N -14.5192 -0.1664 0.0 0
M  V30 22 C -14.5192 2.402 0.0 0
M  V30 23 C -16.0413 -0.1308 0.0 0
M  V30 24 C -16.077 1.3912 0.0 0
M  V30 25 C -16.077 -1.5815 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 9 11
M  V30 11 2 10 12
M  V30 12 1 11 13
M  V30 13 1 13 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 2 17 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 23 25
M  V30 25 1 6 8
M  V30 26 1 12 13
M  V30 27 1 18 19
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00077001.cdx

>  <name>
US20220000789A1-20220106-C00038

>  <Row No>
805

$$$$
US20220000789A1-20220106-C00039
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3195 -0.7132 0.0 0 CFG=2
M  V30 3 C 1.2482 -0.7132 0.0 0
M  V30 4 O -2.6391 0.0475 0.0 0
M  V30 5 C -1.3552 -2.1635 0.0 0
M  V30 6 C 1.2125 -2.1635 0.0 0
M  V30 7 C -3.9586 -0.6657 0.0 0
M  V30 8 C -0.1069 -2.8887 0.0 0
M  V30 9 C -5.2782 0.0951 0.0 0
M  V30 10 N -5.3138 1.6167 0.0 0
M  V30 11 C -6.7285 -0.3328 0.0 0
M  V30 12 N -6.7642 2.116 0.0 0
M  V30 13 N -7.632 0.9034 0.0 0
M  V30 14 C -9.1536 0.9391 0.0 0
M  V30 15 C -9.9263 2.2586 0.0 0
M  V30 16 C -9.9263 -0.309 0.0 0
M  V30 17 C -11.448 2.2943 0.0 0
M  V30 18 C -11.448 -0.2734 0.0 0
M  V30 19 C -12.2207 1.0461 0.0 0
M  V30 20 C -12.2207 3.6139 0.0 0
M  V30 21 C -13.7423 1.0817 0.0 0
M  V30 22 N -14.5151 -0.1664 0.0 0
M  V30 23 C -16.0367 -0.1307 0.0 0
M  V30 24 C -16.0724 1.3908 0.0 0
M  V30 25 C -16.0724 -1.581 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4 CFG=1
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 9 11
M  V30 11 2 10 12
M  V30 12 1 11 13
M  V30 13 1 13 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 2 17 19
M  V30 19 1 17 20
M  V30 20 1 19 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 23 25
M  V30 25 1 6 8
M  V30 26 1 12 13
M  V30 27 1 18 19
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00078001.cdx

>  <name>
US20220000789A1-20220106-C00039

>  <Row No>
806

$$$$
US20220000789A1-20220106-C00040
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.3221 -0.7146 0.0 0 CFG=2
M  V30 3 C 1.2507 -0.7146 0.0 0
M  V30 4 O -2.6443 0.0476 0.0 0
M  V30 5 C -1.3579 -2.1678 0.0 0
M  V30 6 C 1.2149 -2.1678 0.0 0
M  V30 7 C -3.9665 -0.667 0.0 0
M  V30 8 C -0.1072 -2.8825 0.0 0
M  V30 9 C -5.2886 0.0952 0.0 0
M  V30 10 N -5.3244 1.6199 0.0 0
M  V30 11 C -6.7418 -0.3335 0.0 0
M  V30 12 N -6.7776 2.1202 0.0 0
M  V30 13 N -7.6471 0.9052 0.0 0
M  V30 14 C -9.1718 0.941 0.0 0
M  V30 15 C -9.9341 2.2631 0.0 0
M  V30 16 C -11.4588 2.2989 0.0 0
M  V30 17 N -12.2211 1.0482 0.0 0
M  V30 18 C -13.7458 1.0839 0.0 0
M  V30 19 C -13.7815 2.6086 0.0 0
M  V30 20 C -13.7815 -0.3692 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4 CFG=1
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 2 9 11
M  V30 11 2 10 12
M  V30 12 1 11 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 6 8
M  V30 21 1 12 13
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00079001.cdx

>  <name>
US20220000789A1-20220106-C00040

>  <Row No>
807

$$$$
US20220000789A1-20220106-C00041
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.462 -0.3537 0.0 0
M  V30 3 C -0.4244 1.462 0.0 0
M  V30 4 C -1.8864 1.1083 0.0 0
M  V30 5 O -3.1952 1.8746 0.0 0
M  V30 6 C -4.5039 1.1672 0.0 0
M  V30 7 C -5.8126 1.9336 0.0 0
M  V30 8 N -5.848 3.4428 0.0 0
M  V30 9 C -7.2511 1.5091 0.0 0
M  V30 10 N -7.2864 3.938 0.0 0
M  V30 11 N -8.1471 2.7353 0.0 0
M  V30 12 C -9.6563 2.7707 0.0 0
M  V30 13 C -10.4227 1.5327 0.0 0
M  V30 14 C -10.4227 4.0794 0.0 0
M  V30 15 C -11.9319 1.5681 0.0 0
M  V30 16 C -11.9319 4.1148 0.0 0
M  V30 17 C -12.6982 2.8768 0.0 0
M  V30 18 C -14.2074 2.9122 0.0 0
M  V30 19 N -14.9738 1.6742 0.0 0
M  V30 20 C -16.483 1.7096 0.0 0
M  V30 21 C -16.5183 3.2187 0.0 0
M  V30 22 C -16.5183 0.2711 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 4 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 2 7 9
M  V30 9 2 8 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 2 15 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 20 22
M  V30 22 1 3 4
M  V30 23 1 10 11
M  V30 24 1 16 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00080001.cdx

>  <name>
US20220000789A1-20220106-C00041

>  <Row No>
808

$$$$
US20220000789A1-20220106-C00042
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.319 -0.713 0.0 0
M  V30 3 C 1.2477 -0.713 0.0 0
M  V30 4 C -2.6381 0.0475 0.0 0
M  V30 5 C 1.2121 -2.1627 0.0 0
M  V30 6 N -2.6737 1.5686 0.0 0
M  V30 7 C -4.0879 -0.3802 0.0 0
M  V30 8 O 2.4598 -2.8758 0.0 0
M  V30 9 N -4.1235 2.0677 0.0 0
M  V30 10 N -4.991 0.8556 0.0 0
M  V30 11 C 3.7076 -2.1152 0.0 0
M  V30 12 C -6.5121 0.8912 0.0 0
M  V30 13 C 3.6719 -0.5941 0.0 0
M  V30 14 C -7.2845 -0.3565 0.0 0
M  V30 15 C -7.2845 2.2103 0.0 0
M  V30 16 O 2.3529 0.1663 0.0 0
M  V30 17 C -8.8056 -0.3208 0.0 0
M  V30 18 C -8.8056 2.2459 0.0 0
M  V30 19 C 2.3172 1.6874 0.0 0
M  V30 20 C -9.578 0.9982 0.0 0
M  V30 21 C -11.0991 1.0338 0.0 0
M  V30 22 N -11.8716 -0.2139 0.0 0
M  V30 23 C -13.3926 -0.1782 0.0 0
M  V30 24 C -13.4283 1.3428 0.0 0
M  V30 25 C -13.4283 -1.628 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 2 12 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 1 16 19
M  V30 19 2 17 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 23 25
M  V30 25 1 9 10
M  V30 26 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00081001.cdx

>  <name>
US20220000789A1-20220106-C00042

>  <Row No>
809

$$$$
US20220000789A1-20220106-C00043
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 N 1.3958 -0.4331 0.0 0
M  V30 3 N -0.9145 -1.1792 0.0 0
M  V30 4 C 1.3597 -1.9012 0.0 0
M  V30 5 C -2.4547 -1.1431 0.0 0
M  V30 6 C -0.0721 -2.3584 0.0 0
M  V30 7 C 2.6231 -2.6231 0.0 0
M  V30 8 C -3.2368 -2.4066 0.0 0
M  V30 9 C -3.2368 0.1925 0.0 0
M  V30 10 N 3.8866 -1.841 0.0 0
M  V30 11 C -4.7771 -2.3705 0.0 0
M  V30 12 C -4.7771 0.2286 0.0 0
M  V30 13 C 5.1501 -2.563 0.0 0
M  V30 14 C 3.8505 -0.3008 0.0 0
M  V30 15 C -5.5472 -1.0348 0.0 0
M  V30 16 C 6.4135 -1.7929 0.0 0
M  V30 17 C 5.114 0.4692 0.0 0
M  V30 18 C -7.0874 -0.9987 0.0 0
M  V30 19 N 6.3774 -0.2526 0.0 0
M  V30 20 N -7.8695 -2.2622 0.0 0
M  V30 21 C 7.6409 0.5174 0.0 0
M  V30 22 C -9.4098 -2.2261 0.0 0
M  V30 23 C -9.4459 -0.6858 0.0 0
M  V30 24 C -9.4459 -3.6941 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 2 9 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 2 11 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 22 23
M  V30 23 1 22 24
M  V30 24 2 4 6
M  V30 25 1 12 15
M  V30 26 1 17 19
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00082001.cdx

>  <name>
US20220000789A1-20220106-C00043

>  <Row No>
810

$$$$
US20220000789A1-20220106-C00044
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 18 19 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.4605 -0.3533 0.0 0
M  V30 3 C -0.424 1.4605 0.0 0
M  V30 4 C -1.8846 1.1072 0.0 0
M  V30 5 O -3.192 1.861 0.0 0
M  V30 6 C -4.4994 1.1543 0.0 0
M  V30 7 C -5.8069 1.9081 0.0 0
M  V30 8 N -5.8422 3.4158 0.0 0
M  V30 9 C -7.2439 1.4841 0.0 0
M  V30 10 N -7.2792 3.9105 0.0 0
M  V30 11 N -8.1391 2.7091 0.0 0
M  V30 12 C -9.6468 2.7444 0.0 0
M  V30 13 C -10.4006 4.0518 0.0 0
M  V30 14 C -11.9083 4.0872 0.0 0
M  V30 15 N -12.6621 2.8504 0.0 0
M  V30 16 C -14.1698 2.8857 0.0 0
M  V30 17 C -14.2051 4.3934 0.0 0
M  V30 18 C -14.2051 1.4487 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 4 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 2 7 9
M  V30 9 2 8 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 16 18
M  V30 18 1 3 4
M  V30 19 1 10 11
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00083001.cdx

>  <name>
US20220000789A1-20220106-C00044

>  <Row No>
811

$$$$
US20220000789A1-20220106-C00045
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 16 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.1188 1.5087 0.0 0
M  V30 3 O 1.4374 2.1621 0.0 0
M  V30 4 C -1.1167 2.4116 0.0 0
M  V30 5 C 2.6017 1.3305 0.0 0
M  V30 6 N -1.1523 3.9322 0.0 0
M  V30 7 C -2.566 1.9839 0.0 0
M  V30 8 C 3.9204 1.9839 0.0 0
M  V30 9 C -2.6017 4.4312 0.0 0
M  V30 10 N -3.4689 3.2194 0.0 0
M  V30 11 C -4.9896 3.2551 0.0 0
M  V30 12 C -5.7618 2.0077 0.0 0
M  V30 13 N -7.2824 2.0433 0.0 0
M  V30 14 C -8.3635 3.1244 0.0 0
M  V30 15 C -9.4446 2.1146 0.0 0
M  V30 16 C -7.3537 4.2055 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 1 14 15
M  V30 15 1 14 16
M  V30 16 1 9 10
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00084001.cdx

>  <name>
US20220000789A1-20220106-C00045

>  <Row No>
812

$$$$
US20220000789A1-20220106-C00046
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 19 20 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 1.251 0.7625 0.0 0
M  V30 3 O 1.0127 -1.0127 0.0 0
M  V30 4 C -0.7744 -1.251 0.0 0
M  V30 5 C -0.7744 1.3225 0.0 0
M  V30 6 C -2.2995 -1.2153 0.0 0
M  V30 7 C -2.2995 1.3582 0.0 0
M  V30 8 N -3.0621 0.1072 0.0 0
M  V30 9 C -4.5872 0.1429 0.0 0
M  V30 10 C -5.3497 -1.108 0.0 0
M  V30 11 C -5.3497 1.4655 0.0 0
M  V30 12 C -6.8748 -1.0723 0.0 0
M  V30 13 C -6.8748 1.5012 0.0 0
M  V30 14 C -7.6374 0.2502 0.0 0
M  V30 15 C -9.1624 0.2859 0.0 0
M  V30 16 N -9.925 -0.9651 0.0 0
M  V30 17 C -11.4501 -0.9293 0.0 0
M  V30 18 C -11.4858 0.5957 0.0 0
M  V30 19 C -11.4858 -2.3829 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 2 11 13
M  V30 13 2 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 17 19
M  V30 19 1 7 8
M  V30 20 1 13 14
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00085001.cdx

>  <name>
US20220000789A1-20220106-C00046

>  <Row No>
813

$$$$
US20220000789A1-20220106-C00047
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.0357 1.5234 0.0 0
M  V30 3 O 1.4044 0.4284 0.0 0
M  V30 4 C 0.357 -1.4044 0.0 0
M  V30 5 C -1.4758 0.4284 0.0 0
M  V30 6 C -0.726 -2.416 0.0 0
M  V30 7 C -2.5589 -0.5831 0.0 0
M  V30 8 N -2.2018 -1.9876 0.0 0
M  V30 9 C -3.2849 -2.9992 0.0 0
M  V30 10 C -4.7607 -2.8326 0.0 0
M  V30 11 N -5.6652 -1.5948 0.0 0
M  V30 12 C -5.6652 -3.999 0.0 0
M  V30 13 N -7.1173 -2.0233 0.0 0
M  V30 14 N -7.1173 -3.4991 0.0 0
M  V30 15 C -8.4384 -4.2132 0.0 0
M  V30 16 C -9.7595 -3.4396 0.0 0
M  V30 17 O -11.0806 -4.1537 0.0 0
M  V30 18 C -12.4017 -3.3801 0.0 0
M  V30 19 C -13.7228 -4.0942 0.0 0
M  V30 20 C -15.0439 -3.3206 0.0 0
M  V30 21 C -16.365 -4.0347 0.0 0
M  V30 22 C -17.1386 -2.7136 0.0 0
M  V30 23 C -15.6509 -5.2844 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 2 10 12
M  V30 12 2 11 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 21 23
M  V30 23 1 7 8
M  V30 24 1 13 14
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00086001.cdx

>  <name>
US20220000789A1-20220106-C00047

>  <Row No>
814

$$$$
US20220000789A1-20220106-C00048
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.0356 1.5212 0.0 0
M  V30 3 O 1.4023 0.4278 0.0 0
M  V30 4 C 0.3565 -1.4023 0.0 0
M  V30 5 C -1.4736 0.4278 0.0 0
M  V30 6 C -0.7249 -2.4125 0.0 0
M  V30 7 C -2.5551 -0.5823 0.0 0
M  V30 8 N -2.1986 -1.9847 0.0 0
M  V30 9 C -3.2801 -2.9949 0.0 0
M  V30 10 C -4.7538 -2.8285 0.0 0
M  V30 11 N -5.657 -1.5925 0.0 0
M  V30 12 C -5.657 -3.9932 0.0 0
M  V30 13 N -7.107 -2.0203 0.0 0
M  V30 14 N -7.107 -3.494 0.0 0
M  V30 15 C -8.4262 -4.2071 0.0 0
M  V30 16 C -9.7454 -3.4346 0.0 0
M  V30 17 O -11.0646 -4.1477 0.0 0
M  V30 18 C -12.3838 -3.3752 0.0 0
M  V30 19 C -13.7029 -4.0883 0.0 0
M  V30 20 O -15.0221 -3.3158 0.0 0
M  V30 21 C -16.3413 -4.0288 0.0 0
M  V30 22 C -17.6605 -3.2563 0.0 0
M  V30 23 N -18.9797 -3.9694 0.0 0
M  V30 24 C -20.2989 -3.1969 0.0 0
M  V30 25 C -19.5858 -1.8777 0.0 0
M  V30 26 C -21.0595 -4.4448 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 2 10 12
M  V30 12 2 11 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 1 24 26
M  V30 26 1 7 8
M  V30 27 1 13 14
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00087001.cdx

>  <name>
US20220000789A1-20220106-C00048

>  <Row No>
815

$$$$
US20220000789A1-20220106-C00049
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 32 33 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.0355 1.5186 0.0 0
M  V30 3 O 1.3999 0.4271 0.0 0
M  V30 4 C 0.3559 -1.3999 0.0 0
M  V30 5 C -1.4711 0.4271 0.0 0
M  V30 6 C -0.7237 -2.4084 0.0 0
M  V30 7 C -2.5508 -0.5813 0.0 0
M  V30 8 N -2.1948 -1.9813 0.0 0
M  V30 9 C -3.2745 -2.9897 0.0 0
M  V30 10 C -4.7457 -2.8236 0.0 0
M  V30 11 N -5.6473 -1.5898 0.0 0
M  V30 12 C -5.6473 -3.9863 0.0 0
M  V30 13 N -7.0948 -2.0169 0.0 0
M  V30 14 N -7.0948 -3.488 0.0 0
M  V30 15 C -8.4117 -4.1999 0.0 0
M  V30 16 C -9.7287 -3.4287 0.0 0
M  V30 17 O -11.0456 -4.1406 0.0 0
M  V30 18 C -12.3625 -3.3694 0.0 0
M  V30 19 C -13.6795 -4.0813 0.0 0
M  V30 20 O -14.9964 -3.3101 0.0 0
M  V30 21 C -16.3133 -4.0219 0.0 0
M  V30 22 C -17.6303 -3.2508 0.0 0
M  V30 23 O -18.9472 -3.9626 0.0 0
M  V30 24 C -20.2641 -3.1914 0.0 0
M  V30 25 C -21.5811 -3.9033 0.0 0
M  V30 26 O -22.898 -3.1321 0.0 0
M  V30 27 C -24.2149 -3.844 0.0 0
M  V30 28 C -25.5319 -3.0728 0.0 0
M  V30 29 N -26.8488 -3.7847 0.0 0
M  V30 30 C -28.1658 -3.0135 0.0 0
M  V30 31 C -27.4539 -1.6965 0.0 0
M  V30 32 C -28.9251 -4.2592 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 2 10 12
M  V30 12 2 11 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 26 1 26 27
M  V30 27 1 27 28
M  V30 28 1 28 29
M  V30 29 1 29 30
M  V30 30 1 30 31
M  V30 31 1 30 32
M  V30 32 1 7 8
M  V30 33 1 13 14
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00088001.cdx

>  <name>
US20220000789A1-20220106-C00049

>  <Row No>
816

$$$$
US20220000789A1-20220106-C00050
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.2251 -1.4218 0.0 0
M  V30 3 O 1.3626 -0.4739 0.0 0
M  V30 4 C -1.5166 0.1658 0.0 0
M  V30 5 C 0.8057 1.2559 0.0 0
M  V30 6 C -2.3935 -1.019 0.0 0
M  V30 7 N -3.9101 -0.8531 0.0 0
M  V30 8 C -4.9884 -1.8602 0.0 0
M  V30 9 C -4.5855 0.5213 0.0 0
M  V30 10 C -6.4577 -1.6944 0.0 0
M  V30 11 N -7.3582 -0.4621 0.0 0
M  V30 12 C -7.3582 -2.8556 0.0 0
M  V30 13 N -8.8038 -0.8886 0.0 0
M  V30 14 N -8.8038 -2.3579 0.0 0
M  V30 15 C -10.119 -3.0807 0.0 0
M  V30 16 C -11.4343 -2.3105 0.0 0
M  V30 17 O -12.7495 -3.0333 0.0 0
M  V30 18 C -14.0648 -2.2631 0.0 0
M  V30 19 C -15.38 -2.9859 0.0 0
M  V30 20 O -16.6953 -2.2157 0.0 0
M  V30 21 C -18.0105 -2.9385 0.0 0
M  V30 22 C -19.3257 -2.1683 0.0 0
M  V30 23 O -20.641 -2.8911 0.0 0
M  V30 24 C -21.9562 -2.1209 0.0 0
M  V30 25 C -23.2715 -2.8437 0.0 0
M  V30 26 C -24.5867 -2.0735 0.0 0
M  V30 27 C -25.902 -2.7963 0.0 0
M  V30 28 C -26.6721 -1.4811 0.0 0
M  V30 29 C -25.1792 -4.0405 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 10 11
M  V30 11 2 10 12
M  V30 12 2 11 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 26 1 26 27
M  V30 27 1 27 28
M  V30 28 1 27 29
M  V30 29 1 13 14
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00089001.cdx

>  <name>
US20220000789A1-20220106-C00050

>  <Row No>
817

$$$$
US20220000789A1-20220106-C00051
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 32 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.2137 -1.437 0.0 0
M  V30 3 C -1.5082 -0.2137 0.0 0
M  V30 4 C -1.2945 -1.6508 0.0 0
M  V30 5 C -0.7007 -2.969 0.0 0
M  V30 6 C -2.8146 -1.4726 0.0 0
M  V30 7 C -1.5914 -4.1448 0.0 0
M  V30 8 C -3.7054 -2.6484 0.0 0
M  V30 9 N -3.1115 -3.9666 0.0 0
M  V30 10 C -4.1923 -4.9761 0.0 0
M  V30 11 C -5.665 -4.8099 0.0 0
M  V30 12 N -6.5676 -3.5747 0.0 0
M  V30 13 C -6.5676 -5.9737 0.0 0
M  V30 14 N -8.0165 -4.0023 0.0 0
M  V30 15 N -8.0165 -5.4749 0.0 0
M  V30 16 C -9.3347 -6.1994 0.0 0
M  V30 17 C -10.653 -5.4274 0.0 0
M  V30 18 O -11.9713 -6.1519 0.0 0
M  V30 19 C -13.2896 -5.3799 0.0 0
M  V30 20 C -14.6078 -6.1044 0.0 0
M  V30 21 O -15.9261 -5.3324 0.0 0
M  V30 22 C -17.2444 -6.0569 0.0 0
M  V30 23 C -18.5626 -5.2849 0.0 0
M  V30 24 O -19.8809 -6.0094 0.0 0
M  V30 25 C -21.1992 -5.2374 0.0 0
M  V30 26 C -22.5175 -5.9619 0.0 0
M  V30 27 C -23.8357 -5.1899 0.0 0
M  V30 28 C -25.154 -5.9144 0.0 0
M  V30 29 C -25.926 -4.5961 0.0 0
M  V30 30 C -24.4295 -7.1614 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 2 11 13
M  V30 13 2 12 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 26 1 26 27
M  V30 27 1 27 28
M  V30 28 1 28 29
M  V30 29 1 28 30
M  V30 30 1 3 4
M  V30 31 1 8 9
M  V30 32 1 14 15
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00090001.cdx

>  <name>
US20220000789A1-20220106-C00051

>  <Row No>
818

$$$$
US20220000789A1-20220106-C00052
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 80 84 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.875 1.0208 0.0 0
M  V30 3 C 1.2638 0.0729 0.0 0
M  V30 4 C -0.4131 -1.2152 0.0 0
M  V30 5 C -1.0208 1.0208 0.0 0
M  V30 6 C -1.7743 -1.4826 0.0 0
M  V30 7 C -2.3819 0.7534 0.0 0
M  V30 8 N -2.7951 -0.4618 0.0 0
M  V30 9 C -4.0347 -1.0694 0.0 0
M  V30 10 C -5.2743 -0.3159 0.0 0
M  V30 11 N -5.3229 1.0937 0.0 0
M  V30 12 C -6.6354 -0.6319 0.0 0
M  V30 13 N -6.6597 1.6041 0.0 0
M  V30 14 N -7.4861 0.5347 0.0 0
M  V30 15 C -8.8958 0.6076 0.0 0
M  V30 16 C -9.6493 -0.4861 0.0 0
M  V30 17 O -11.059 -0.4131 0.0 0
M  V30 18 C -11.8125 -1.5069 0.0 0
M  V30 19 C -13.2223 -1.434 0.0 0
M  V30 20 O -13.9757 -2.5277 0.0 0
M  V30 21 C -15.3855 -2.4548 0.0 0
M  V30 22 C -16.1389 -3.5486 0.0 0
M  V30 23 O -17.5487 -3.4757 0.0 0
M  V30 24 C -18.3021 -4.5694 0.0 0
M  V30 25 C -19.7119 -4.4965 0.0 0
M  V30 26 N -20.4653 -5.5903 0.0 0
M  V30 27 C -21.8751 -5.5173 0.0 0
M  V30 28 C -21.948 -4.1076 0.0 0
M  V30 29 C -21.948 -6.7812 0.0 0
M  V30 30 O -1.3611 11.4722 0.0 0
M  V30 31 C -3.0868 10.8889 0.0 0 CFG=2
M  V30 32 C -0.0729 10.5 0.0 0
M  V30 33 O -4.6423 11.8125 0.0 0
M  V30 34 C -3.4027 9.2118 0.0 0
M  V30 35 C -0.3888 8.8229 0.0 0
M  V30 36 C -6.2222 11.0347 0.0 0
M  V30 37 C -2.1145 8.2396 0.0 0
M  V30 38 C -7.7778 11.9584 0.0 0
M  V30 39 N -7.7778 13.8056 0.0 0
M  V30 40 C -9.5521 11.5695 0.0 0
M  V30 41 N -9.5035 14.4861 0.0 0
M  V30 42 N -10.5729 13.0764 0.0 0
M  V30 43 C -12.4202 13.1493 0.0 0
M  V30 44 C -13.3438 11.7396 0.0 0
M  V30 45 C -13.3438 14.7049 0.0 0
M  V30 46 C -15.191 11.8125 0.0 0
M  V30 47 C -15.191 14.7778 0.0 0
M  V30 48 C -16.1146 13.3924 0.0 0
M  V30 49 C -17.9619 13.4653 0.0 0
M  V30 50 N -18.8855 12.0556 0.0 0
M  V30 51 C -18.9584 10.3542 0.0 0
M  V30 52 C -20.8056 10.4271 0.0 0
M  V30 53 C -17.257 10.4271 0.0 0
M  V30 54 O -13.6111 -24.5001 0.0 0
M  V30 55 C -12.9792 -23.2119 0.0 0
M  V30 56 C -15.0938 -24.4272 0.0 0
M  V30 57 C -11.6424 -23.139 0.0 0
M  V30 58 C -15.8716 -25.5695 0.0 0
M  V30 59 O -11.0104 -21.8508 0.0 0
M  V30 60 O -17.3542 -25.4966 0.0 0
M  V30 61 C -9.6736 -21.7779 0.0 0
M  V30 62 C -18.132 -26.639 0.0 0
M  V30 63 C -9.0417 -20.4897 0.0 0
M  V30 64 C -19.6146 -26.5661 0.0 0
M  V30 65 N -7.7049 -20.4167 0.0 0
M  V30 66 N -20.3924 -27.7084 0.0 0
M  V30 67 N -6.9271 -19.2258 0.0 0
M  V30 68 C -6.9757 -21.4862 0.0 0
M  V30 69 C -21.8751 -27.6355 0.0 0
M  V30 70 N -5.6632 -19.6146 0.0 0
M  V30 71 C -5.7118 -21.0001 0.0 0
M  V30 72 C -21.948 -26.1529 0.0 0
M  V30 73 C -21.948 -28.9723 0.0 0
M  V30 74 C -4.5694 -21.632 0.0 0
M  V30 75 C -4.6423 -22.9688 0.0 0
M  V30 76 C -3.4271 -20.8542 0.0 0
M  V30 77 C -3.5 -23.6008 0.0 0
M  V30 78 C -2.2847 -21.4862 0.0 0
M  V30 79 C -2.3576 -22.823 0.0 0
M  V30 80 C -1.2152 -23.455 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 2 10 12
M  V30 12 2 11 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 26 1 26 27
M  V30 27 1 27 28
M  V30 28 1 27 29
M  V30 29 1 30 31
M  V30 30 1 30 32
M  V30 31 1 31 33 CFG=1
M  V30 32 1 31 34
M  V30 33 1 32 35
M  V30 34 1 33 36
M  V30 35 1 34 37
M  V30 36 1 36 38
M  V30 37 1 38 39
M  V30 38 2 38 40
M  V30 39 2 39 41
M  V30 40 1 40 42
M  V30 41 1 42 43
M  V30 42 2 43 44
M  V30 43 1 43 45
M  V30 44 1 44 46
M  V30 45 2 45 47
M  V30 46 2 46 48
M  V30 47 1 48 49
M  V30 48 1 49 50
M  V30 49 1 50 51
M  V30 50 1 51 52
M  V30 51 1 51 53
M  V30 52 1 54 55
M  V30 53 1 54 56
M  V30 54 1 55 57
M  V30 55 1 56 58
M  V30 56 1 57 59
M  V30 57 1 58 60
M  V30 58 1 59 61
M  V30 59 1 60 62
M  V30 60 1 61 63
M  V30 61 1 62 64
M  V30 62 1 63 65
M  V30 63 1 64 66
M  V30 64 1 65 67
M  V30 65 1 65 68
M  V30 66 1 66 69
M  V30 67 2 67 70
M  V30 68 2 68 71
M  V30 69 1 69 72
M  V30 70 1 69 73
M  V30 71 1 71 74
M  V30 72 2 74 75
M  V30 73 1 74 76
M  V30 74 1 75 77
M  V30 75 2 76 78
M  V30 76 2 77 79
M  V30 77 1 79 80
M  V30 78 1 7 8
M  V30 79 1 13 14
M  V30 80 1 35 37
M  V30 81 1 41 42
M  V30 82 1 47 48
M  V30 83 1 70 71
M  V30 84 1 78 79
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 31)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00091001.cdx

>  <name>
US20220000789A1-20220106-C00052

>  <Row No>
819

$$$$
US20220000789A1-20220106-C00053
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 56 58 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.9527 1.1114 0.0 0
M  V30 3 C 1.3761 0.0793 0.0 0
M  V30 4 C -0.4498 -1.3232 0.0 0
M  V30 5 C -1.1114 1.1114 0.0 0
M  V30 6 C -1.9318 -1.6143 0.0 0
M  V30 7 C -2.5934 0.8203 0.0 0
M  V30 8 N -3.0433 -0.5028 0.0 0
M  V30 9 C -4.393 -1.1644 0.0 0
M  V30 10 C -5.7427 -0.344 0.0 0
M  V30 11 N -5.7956 1.1908 0.0 0
M  V30 12 C -7.2247 -0.688 0.0 0
M  V30 13 N -7.2511 1.7466 0.0 0
M  V30 14 N -8.1509 0.5822 0.0 0
M  V30 15 C -9.6858 0.6616 0.0 0
M  V30 16 C -10.5062 -0.5292 0.0 0
M  V30 17 O -12.0412 -0.4498 0.0 0
M  V30 18 C -12.8616 -1.6407 0.0 0
M  V30 19 C -14.3965 -1.5613 0.0 0
M  V30 20 O -15.2169 -2.7522 0.0 0
M  V30 21 C -16.7518 -2.6728 0.0 0
M  V30 22 C -17.5722 -3.8637 0.0 0
M  V30 23 O -19.1071 -3.7843 0.0 0
M  V30 24 C -19.9275 -4.9752 0.0 0
M  V30 25 C -21.4624 -4.8958 0.0 0
M  V30 26 N -22.2828 -6.0867 0.0 0
M  V30 27 C -23.8177 -6.0073 0.0 0
M  V30 28 C -23.8971 -4.4724 0.0 0
M  V30 29 C -23.8971 -7.3835 0.0 0
M  V30 30 O -14.8199 -26.6759 0.0 0
M  V30 31 C -14.1318 -25.2733 0.0 0
M  V30 32 C -16.4342 -26.5965 0.0 0
M  V30 33 C -12.6763 -25.1939 0.0 0
M  V30 34 C -17.2811 -27.8403 0.0 0
M  V30 35 O -11.9882 -23.7913 0.0 0
M  V30 36 O -18.8954 -27.7609 0.0 0
M  V30 37 C -10.5327 -23.7119 0.0 0
M  V30 38 C -19.7422 -29.0047 0.0 0
M  V30 39 C -9.8446 -22.3093 0.0 0
M  V30 40 C -21.3566 -28.9253 0.0 0
M  V30 41 N -8.3891 -22.2299 0.0 0
M  V30 42 N -22.2034 -30.1691 0.0 0
M  V30 43 N -7.5422 -20.9331 0.0 0
M  V30 44 C -7.5952 -23.3943 0.0 0
M  V30 45 C -23.8177 -30.0898 0.0 0
M  V30 46 N -6.1661 -21.3566 0.0 0
M  V30 47 C -6.219 -22.865 0.0 0
M  V30 48 C -23.8971 -28.4754 0.0 0
M  V30 49 C -23.8971 -31.5453 0.0 0
M  V30 50 C -4.9752 -23.5531 0.0 0
M  V30 51 C -5.0546 -25.0086 0.0 0
M  V30 52 C -3.7314 -22.7062 0.0 0
M  V30 53 C -3.8108 -25.6967 0.0 0
M  V30 54 C -2.4876 -23.3943 0.0 0
M  V30 55 C -2.567 -24.8498 0.0 0
M  V30 56 C -1.3232 -25.5379 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 8 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 2 10 12
M  V30 12 2 11 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 19 20
M  V30 20 1 20 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 26 1 26 27
M  V30 27 1 27 28
M  V30 28 1 27 29
M  V30 29 1 30 31
M  V30 30 1 30 32
M  V30 31 1 31 33
M  V30 32 1 32 34
M  V30 33 1 33 35
M  V30 34 1 34 36
M  V30 35 1 35 37
M  V30 36 1 36 38
M  V30 37 1 37 39
M  V30 38 1 38 40
M  V30 39 1 39 41
M  V30 40 1 40 42
M  V30 41 1 41 43
M  V30 42 1 41 44
M  V30 43 1 42 45
M  V30 44 2 43 46
M  V30 45 2 44 47
M  V30 46 1 45 48
M  V30 47 1 45 49
M  V30 48 1 47 50
M  V30 49 2 50 51
M  V30 50 1 50 52
M  V30 51 1 51 53
M  V30 52 2 52 54
M  V30 53 2 53 55
M  V30 54 1 55 56
M  V30 55 1 7 8
M  V30 56 1 13 14
M  V30 57 1 46 47
M  V30 58 1 54 55
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00092001.cdx

>  <name>
US20220000789A1-20220106-C00053

>  <Row No>
820

$$$$
US20220000789A1-20220106-C00054
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 6 0 0 0
M  V30 BEGIN ATOM
M  V30 1 P 0.0 0.0 0.0 0
M  V30 2 C -4.6066 0.1919 0.0 0
M  V30 3 C -6.1422 0.2279 0.0 0
M  V30 4 C -3.143 0.2279 0.0 0
M  V30 5 A -7.6777 0.2639 0.0 0
M  V30 6 C -1.6795 0.2639 0.0 0
M  V30 7 C 2.4952 0.2879 0.0 0
M  V30 8 C 0.9597 0.3239 0.0 0
M  V30 9 C 3.9588 0.3239 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 3
M  V30 2 1 2 4
M  V30 3 1 3 5
M  V30 4 1 4 6
M  V30 5 1 7 8
M  V30 6 1 7 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00094001.cdx

>  <name>
US20220000789A1-20220106-C00054

>  <Row No>
821

$$$$
US20220000789A1-20220106-C00055
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 6 0 0 0
M  V30 BEGIN ATOM
M  V30 1 P 0.0 0.0 0.0 0
M  V30 2 C -4.6066 0.1919 0.0 0
M  V30 3 C -6.1422 0.2279 0.0 0
M  V30 4 C -3.143 0.2279 0.0 0
M  V30 5 A -7.6777 0.2639 0.0 0
M  V30 6 C -1.6795 0.2639 0.0 0
M  V30 7 C 2.4952 0.2879 0.0 0
M  V30 8 C 0.9597 0.3239 0.0 0
M  V30 9 C 3.9588 0.3239 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 3
M  V30 2 1 2 4
M  V30 3 1 3 5
M  V30 4 1 4 6
M  V30 5 1 7 8
M  V30 6 1 7 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00107001.cdx

>  <name>
US20220000789A1-20220106-C00055

>  <Row No>
822

$$$$
US20220000794A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.1884 0.7987 0.0 0
M  V30 3 C 1.13 2.2794 0.0 0
M  V30 4 C 2.3769 0.1168 0.0 0
M  V30 5 C 2.3379 3.0782 0.0 0
M  V30 6 C -1.3637 3.7017 0.0 0 CFG=2
M  V30 7 C 3.5848 0.9156 0.0 0
M  V30 8 O 2.2794 4.5589 0.0 0
M  V30 9 C 3.5458 2.3963 0.0 0
M  V30 10 C -1.4222 5.1824 0.0 0
M  V30 11 C -2.6496 3.0198 0.0 0 CFG=2
M  V30 12 C 4.7732 0.2337 0.0 0
M  V30 13 C -2.7081 5.9812 0.0 0
M  V30 14 C -2.7081 1.656 0.0 0
M  V30 15 C -3.9355 3.8186 0.0 0
M  V30 16 C 5.9812 1.0325 0.0 0
M  V30 17 C -3.9939 5.2993 0.0 0
M  V30 18 C -2.7665 7.4619 0.0 0
M  V30 19 C -1.5196 0.9741 0.0 0
M  V30 20 C -3.9939 0.9741 0.0 0
M  V30 21 C 7.1891 0.3506 0.0 0
M  V30 22 C 8.3971 1.1494 0.0 0
M  V30 23 C 9.5855 0.4675 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 6 3 CFG=1
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 5 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 2 10 13
M  V30 13 1 11 14 CFG=3
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 2 14 19
M  V30 19 1 14 20
M  V30 20 1 16 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 7 9
M  V30 24 1 15 17
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 6 11)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000794A1-20220106-C00001

>  <Row No>
823

$$$$
US20220000794A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2576 0.7665 0.0 0
M  V30 3 C -1.3295 0.7665 0.0 0
M  V30 4 C 1.2217 2.2996 0.0 0
M  V30 5 C 2.5152 0.0359 0.0 0
M  V30 6 C -1.3654 2.2996 0.0 0 CFG=1
M  V30 7 C -2.8147 0.4072 0.0 0
M  V30 8 C -2.108 -0.491 0.0 0
M  V30 9 C 2.4793 3.0782 0.0 0
M  V30 10 C -0.1077 3.0782 0.0 0 CFG=1
M  V30 11 C 3.7729 0.8144 0.0 0
M  V30 12 C -2.6949 3.0782 0.0 0
M  V30 13 O 2.4434 4.6113 0.0 0
M  V30 14 C 3.737 2.3595 0.0 0
M  V30 15 C -0.1437 4.6113 0.0 0
M  V30 16 C 5.0305 0.0838 0.0 0
M  V30 17 C -2.7308 4.6113 0.0 0
M  V30 18 C -1.4732 5.3779 0.0 0
M  V30 19 C 6.2882 0.8504 0.0 0
M  V30 20 C -1.5091 6.911 0.0 0
M  V30 21 C 7.5458 0.1197 0.0 0
M  V30 22 C 8.8035 0.8863 0.0 0
M  V30 23 C 10.0611 0.1557 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 3 8
M  V30 8 1 4 9
M  V30 9 1 4 10
M  V30 10 2 5 11
M  V30 11 1 6 12 CFG=3
M  V30 12 1 9 13
M  V30 13 2 9 14
M  V30 14 1 10 15 CFG=1
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 2 15 18
M  V30 18 1 16 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 6 10
M  V30 24 1 11 14
M  V30 25 1 17 18
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 6 10)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000794A1-20220106-C00002

>  <Row No>
824

$$$$
US20220000796A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.1909 0.7875 0.0 0
M  V30 3 C 1.1333 2.2859 0.0 0
M  V30 4 C 2.3819 0.1152 0.0 0
M  V30 5 C 2.3243 3.0735 0.0 0
M  V30 6 C -1.3254 3.8227 0.0 0 CFG=2
M  V30 7 C 3.5729 0.9028 0.0 0
M  V30 8 O 2.2667 4.5718 0.0 0
M  V30 9 C 3.5153 2.4012 0.0 0
M  V30 10 C -1.383 5.321 0.0 0
M  V30 11 C -2.6125 3.1503 0.0 0 CFG=2
M  V30 12 C 4.7639 0.2305 0.0 0
M  V30 13 C -2.6701 6.1086 0.0 0
M  V30 14 C -2.6701 1.7672 0.0 0
M  V30 15 C -3.8995 3.9379 0.0 0
M  V30 16 C 5.9549 1.0181 0.0 0
M  V30 17 C -3.9571 5.4363 0.0 0
M  V30 18 C -2.7277 7.607 0.0 0
M  V30 19 C -1.4791 1.0949 0.0 0
M  V30 20 C -3.9571 1.0949 0.0 0
M  V30 21 C 7.1459 0.3457 0.0 0
M  V30 22 C 8.3369 1.1333 0.0 0
M  V30 23 C 9.5279 0.461 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 6 3 CFG=1
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 5 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 2 10 13
M  V30 13 1 11 14 CFG=3
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 2 14 19
M  V30 19 1 14 20
M  V30 20 1 16 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 7 9
M  V30 24 1 15 17
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 6 11)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000796A1-20220106-C00001

>  <Row No>
825

$$$$
US20220000798A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 17 18 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0351 -1.4764 0.0 0
M  V30 3 C 1.2421 -2.1913 0.0 0
M  V30 4 C -1.3827 -2.1913 0.0 0
M  V30 5 C 1.2069 -3.6677 0.0 0
M  V30 6 C -1.4179 -3.6677 0.0 0
M  V30 7 O 2.4842 -4.3708 0.0 0
M  V30 8 C -0.1406 -4.3708 0.0 0
M  V30 9 C -2.7654 -4.3708 0.0 0
M  V30 10 C -2.8006 -5.8473 0.0 0
M  V30 11 C -4.1482 -6.5504 0.0 0
M  V30 12 C -4.1834 -8.0269 0.0 0
M  V30 13 C -5.4958 -5.7653 0.0 0
M  V30 14 C -5.5309 -8.73 0.0 0
M  V30 15 C -6.8434 -6.4684 0.0 0
M  V30 16 C -6.8785 -7.9332 0.0 0
M  V30 17 O -8.2261 -8.6363 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 2 9 10
M  V30 10 1 10 11
M  V30 11 2 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 2 13 15
M  V30 15 2 14 16
M  V30 16 1 16 17
M  V30 17 1 6 8
M  V30 18 1 15 16
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000798A1-20220106-C00001

>  <Row No>
826

$$$$
US20220000799A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 6 3 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Y 0.0 0.0 0.0 0 VAL=1
M  V30 2 C 1.4995 0.0357 0.0 0
M  V30 3 C 2.9991 0.0714 0.0 0
M  V30 4 C 4.4987 0.1071 0.0 0
M  V30 5 C 0.6664 0.2856 0.0 0
M  V30 6 C 2.0946 0.2856 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000799A1-20220106-C00001

>  <Row No>
827

$$$$
US20220000799A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 6 3 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C 1.4753 0.0362 0.0 0
M  V30 3 A -1.5479 0.0362 0.0 0
M  V30 4 C 2.9507 0.0725 0.0 0
M  V30 5 C -0.8707 0.2902 0.0 0
M  V30 6 C 0.5804 0.2902 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000799A1-20220106-C00002

>  <Row No>
828

$$$$
US20220000799A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 6 3 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C 1.4753 0.0362 0.0 0
M  V30 3 A -1.5479 0.0362 0.0 0
M  V30 4 C 2.9507 0.0725 0.0 0
M  V30 5 C -0.8707 0.2902 0.0 0
M  V30 6 C 0.5804 0.2902 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000799A1-20220106-C00003

>  <Row No>
829

$$$$
US20220000799A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C -0.0362 -1.4759 0.0 0
M  V30 3 C 1.2702 0.7863 0.0 0
M  V30 4 C 1.2339 -2.2018 0.0 0
M  V30 5 C 2.5405 0.0604 0.0 0
M  V30 6 C 2.5042 -1.4154 0.0 0
M  V30 7 C 3.5809 -0.4839 0.0 0
M  V30 8 C 2.0324 -0.4476 0.0 0
M  V30 9 C 5.0569 -0.4476 0.0 0
M  V30 10 C 3.5447 1.0646 0.0 0
M  V30 11 C 3.5447 -1.9598 0.0 0
M  V30 12 C 0.0 -0.2903 0.0 0
M  V30 13 C -1.3428 0.4839 0.0 0
M  V30 14 C 0.0 -0.6774 0.0 0
M  V30 15 C -1.3428 -1.4154 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 2 4 6
M  V30 6 1 7 8
M  V30 7 1 7 9
M  V30 8 1 7 10
M  V30 9 1 7 11
M  V30 10 1 12 13
M  V30 11 1 14 15
M  V30 12 1 5 6
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000799A1-20220106-C00004

>  <Row No>
830

$$$$
US20220000799A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 4 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Y 0.0 0.0 0.0 0 VAL=1
M  V30 2 C 1.4813 0.0364 0.0 0
M  V30 3 C 2.9626 0.0728 0.0 0
M  V30 4 C 1.1656 5.9253 0.0 0
M  V30 5 A -0.3885 5.9618 0.0 0
M  V30 6 C 2.6469 5.9618 0.0 0
M  V30 7 C 0.6799 0.2914 0.0 0
M  V30 8 C 2.137 0.2914 0.0 0
M  V30 9 C 0.5828 5.9253 0.0 0
M  V30 10 C 2.0398 5.9253 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 4 5
M  V30 4 1 4 6
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000799A1-20220106-C00005

>  <Row No>
831

$$$$
US20220000799A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 6 3 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Y 0.0 0.0 0.0 0 VAL=1
M  V30 2 C 1.4995 0.0357 0.0 0
M  V30 3 C 2.9991 0.0714 0.0 0
M  V30 4 C 4.4987 0.1071 0.0 0
M  V30 5 C 0.6664 0.2856 0.0 0
M  V30 6 C 2.0946 0.2856 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000799A1-20220106-C00006

>  <Row No>
832

$$$$
US20220000799A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 ? 1.2999 -0.7411 0.0 0
M  V30 3 C 2.5756 0.0364 0.0 0
M  V30 4 C 3.8513 -0.6925 0.0 0
M  V30 5 C 2.5392 1.5915 0.0 0
M  V30 6 C 5.127 0.085 0.0 0
M  V30 7 C 3.8149 2.3812 0.0 0
M  V30 8 C 5.0906 1.6401 0.0 0
M  V30 9 C 6.4027 -0.6439 0.0 0
M  V30 10 C 6.3663 2.4298 0.0 0
M  V30 11 C 7.6784 0.1336 0.0 0
M  V30 12 C 7.642 1.7009 0.0 0
M  V30 13 C 6.3298 3.985 0.0 0
M  V30 14 C 8.9177 2.4906 0.0 0
M  V30 15 C 7.6055 4.7625 0.0 0
M  V30 16 C 8.8812 4.0457 0.0 0
M  V30 17 C 10.327 2.0532 0.0 0
M  V30 18 C 10.2905 4.556 0.0 0
M  V30 19 C 9.1849 5.3093 0.0 0
M  V30 20 C 11.1775 3.3168 0.0 0
M  V30 21 C 9.8532 6.0625 0.0 0
M  V30 22 C 11.5662 5.3457 0.0 0
M  V30 23 A 3.6934 1.0691 0.0 0
M  V30 24 C 7.5812 3.4018 0.0 0
M  V30 25 B 6.2205 1.0691 0.0 0
M  V30 26 H 10.1083 3.4018 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 2 3 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 2 6 8
M  V30 8 1 6 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 10 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 1 14 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 1 7 8
M  V30 23 1 11 12
M  V30 24 1 15 16
M  V30 25 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000799A1-20220106-C00007

>  <Row No>
833

$$$$
US20220000799A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 30 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2827 0.7672 0.0 0
M  V30 3 C 2.5655 0.0359 0.0 0
M  V30 4 C 1.2708 2.2898 0.0 0
M  V30 5 C 3.8483 0.8032 0.0 0
M  V30 6 C 2.5535 3.0571 0.0 0
M  V30 7 C 3.8363 2.3138 0.0 0
M  V30 8 C 5.1311 0.0599 0.0 0
M  V30 9 C 5.1191 3.081 0.0 0
M  V30 10 C 3.8004 3.8483 0.0 0
M  V30 11 C 6.4139 0.8272 0.0 0
M  V30 12 C 6.4019 2.3377 0.0 0
M  V30 13 C 5.1071 4.5916 0.0 0
M  V30 14 C 7.6847 3.105 0.0 0
M  V30 15 C 6.3899 5.3589 0.0 0
M  V30 16 C 3.7764 5.3709 0.0 0
M  V30 17 C 7.6727 4.6156 0.0 0
M  V30 18 C 9.0874 2.6495 0.0 0
M  V30 19 C 9.0874 5.0951 0.0 0
M  V30 20 C 8.0324 6.1022 0.0 0
M  V30 21 C 9.9506 3.8723 0.0 0
M  V30 22 O 10.574 5.1071 0.0 0
M  V30 23 C 9.8067 6.4259 0.0 0
M  V30 24 ? 11.3053 6.4139 0.0 0
M  V30 25 O 9.0394 7.7566 0.0 0
M  V30 26 C 11.2693 6.4619 0.0 0
M  V30 27 A 2.4936 1.7263 0.0 0
M  V30 28 C 6.2341 3.9322 0.0 0
M  V30 29 B 5.0832 1.7263 0.0 0
M  V30 30 H 8.7277 3.9322 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 1 9 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 14 18
M  V30 18 1 17 19
M  V30 19 1 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 19 23
M  V30 23 1 22 24
M  V30 24 2 23 25
M  V30 25 1 23 26
M  V30 26 1 6 7
M  V30 27 1 11 12
M  V30 28 1 15 17
M  V30 29 1 19 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000799A1-20220106-C00008

>  <Row No>
834

$$$$
US20220000799A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C -1.3257 -0.7032 0.0 0 CFG=2
M  V30 3 C -2.6515 0.0922 0.0 0
M  V30 4 C -1.3603 -2.1557 0.0 0
M  V30 5 C -3.9772 -0.6109 0.0 0
M  V30 6 C -5.303 0.1844 0.0 0
M  V30 7 C -4.0118 -2.0635 0.0 0
M  V30 8 C -6.6287 -0.5187 0.0 0
M  V30 9 C -5.3375 -2.7667 0.0 0
M  V30 10 C -6.6633 -1.9713 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=1
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 2 8 10
M  V30 10 1 9 10
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000799A1-20220106-C00009

>  <Row No>
835

$$$$
US20220000799A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 19 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C 1.4361 -0.2919 0.0 0
M  V30 3 C -1.2143 -0.9107 0.0 0
M  V30 4 C 2.0433 -1.6113 0.0 0
M  V30 5 C 2.4753 0.8173 0.0 0
M  V30 6 C -1.2493 -2.3819 0.0 0
M  V30 7 C -2.5571 -0.105 0.0 0
M  V30 8 N 1.3661 -2.9307 0.0 0
M  V30 9 C -0.105 -3.2927 0.0 0
M  V30 10 C -2.5921 -3.0825 0.0 0
M  V30 11 C -3.8999 -0.8173 0.0 0
M  V30 12 C -0.5254 -4.7172 0.0 0
M  V30 13 C -3.9349 -2.2885 0.0 0
M  V30 14 C -2.02 -5.0675 0.0 0
M  V30 15 C 0.5137 -5.7564 0.0 0
M  V30 16 C -5.2777 -2.9891 0.0 0
M  V30 17 C -2.4403 -6.492 0.0 0
M  V30 18 C 0.0934 -7.1809 0.0 0
M  V30 19 C -1.4011 -7.5312 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 2 3 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 2 7 11
M  V30 11 1 9 12
M  V30 12 2 10 13
M  V30 13 2 12 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 2 15 18
M  V30 18 2 17 19
M  V30 19 2 8 9
M  V30 20 1 11 13
M  V30 21 1 18 19
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000799A1-20220106-C00010

>  <Row No>
836

$$$$
US20220000799A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.31 -0.7317 0.0 0
M  V30 3 N -2.62 0.0236 0.0 0
M  V30 4 N -1.3454 -2.1951 0.0 0
M  V30 5 C -3.9536 -0.6845 0.0 0
M  V30 6 ? -2.6318 1.5342 0.0 0
M  V30 7 C -2.679 -2.9033 0.0 0
M  V30 8 O -5.2873 0.0944 0.0 0
M  V30 9 C -3.989 -2.1479 0.0 0
M  V30 10 O -2.7144 -4.3667 0.0 0
M  V30 11 ? -4.0245 -3.6114 0.0 0
M  V30 12 ? -5.3227 -1.369 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 7 10
M  V30 10 1 9 11
M  V30 11 1 9 12
M  V30 12 1 7 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000799A1-20220106-C00011

>  <Row No>
837

$$$$
US20220000799A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -1.4469 0.9937 0.0 0
M  V30 3 C 1.3772 1.0285 0.0 0 CFG=2
M  V30 4 C -2.8939 1.0111 0.0 0
M  V30 5 C -0.767 2.2837 0.0 0
M  V30 6 C 0.6101 2.3012 0.0 0 CFG=2
M  V30 7 C 2.7545 1.0808 0.0 0
M  V30 8 C -3.6784 2.3012 0.0 0
M  V30 9 ? -3.6436 -0.2092 0.0 0
M  V30 10 C -1.5515 3.5738 0.0 0
M  V30 11 C 1.29 3.5913 0.0 0
M  V30 12 C 2.2314 4.5327 0.0 0
M  V30 13 C 3.4344 2.3709 0.0 0
M  V30 14 C 3.4344 -0.1046 0.0 0
M  V30 15 C -2.9985 3.5913 0.0 0
M  V30 16 C -0.8716 4.8639 0.0 0
M  V30 17 C 2.6673 3.6436 0.0 0
M  V30 18 C 0.5055 4.8813 0.0 0 CFG=1
M  V30 19 C 2.9985 4.8988 0.0 0
M  V30 20 N 1.691 5.6659 0.0 0
M  V30 21 C 1.6387 7.1477 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 3 1 CFG=3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 4 9
M  V30 9 2 5 10
M  V30 10 1 6 11
M  V30 11 1 6 12 CFG=1
M  V30 12 1 7 13
M  V30 13 1 7 14
M  V30 14 2 8 15
M  V30 15 1 10 16
M  V30 16 1 11 17
M  V30 17 1 11 18
M  V30 18 1 12 19
M  V30 19 1 18 20 CFG=1
M  V30 20 1 20 21
M  V30 21 1 5 6
M  V30 22 1 10 15
M  V30 23 2 13 17
M  V30 24 1 16 18
M  V30 25 1 19 20
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 3 6 18)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000799A1-20220106-C00012

>  <Row No>
838

$$$$
US20220000799A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 9 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 C -1.4689 -0.4334 0.0 0 CFG=2
M  V30 3 C 0.8428 -1.1799 0.0 0
M  V30 4 N -1.505 -1.9023 0.0 0
M  V30 5 C -3.01 -0.3973 0.0 0
M  V30 6 C -0.0722 -2.3598 0.0 0
M  V30 7 C -3.0461 -1.8662 0.0 0
M  V30 8 O -4.1418 -2.8896 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=3
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 7 8
M  V30 8 1 4 6
M  V30 9 1 5 7
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000799A1-20220106-C00013

>  <Row No>
839

$$$$
US20220000799A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 10 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 C -1.3417 -0.7252 0.0 0 CFG=2
M  V30 3 C 1.2692 -0.7252 0.0 0
M  V30 4 N -1.378 -2.1999 0.0 0
M  V30 5 C -2.8889 -0.689 0.0 0
M  V30 6 C 1.2329 -2.1999 0.0 0
M  V30 7 C -2.9252 -2.1637 0.0 0
M  V30 8 C -0.1087 -2.9252 0.0 0
M  V30 9 O -4.0252 -3.1911 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=3
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 4 8
M  V30 8 2 7 9
M  V30 9 1 5 7
M  V30 10 2 6 8
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000799A1-20220106-C00014

>  <Row No>
840

$$$$
US20220000799A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 9 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.0242 1.0965 0.0 0
M  V30 3 N 2.4944 1.1327 0.0 0
M  V30 4 C 0.9881 2.639 0.0 0
M  V30 5 C 3.8922 0.6989 0.0 0
M  V30 6 C 2.4582 2.6752 0.0 0 CFG=1
M  V30 7 C 4.7358 1.9521 0.0 0
M  V30 8 C 3.8561 3.1813 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 6 3 CFG=1
M  V30 6 2 5 7
M  V30 7 1 6 8
M  V30 8 1 4 6
M  V30 9 1 7 8
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 6)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00035001.cdx

>  <name>
US20220000799A1-20220106-C00015

>  <Row No>
841

$$$$
US20220000799A1-20220106-C00016
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 34 37 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.012 1.5181 0.0 0
M  V30 3 C -1.3253 2.2892 0.0 0
M  V30 4 C 1.253 2.3013 0.0 0
M  V30 5 C -2.6628 1.5543 0.0 0
M  V30 6 C -1.3374 3.8074 0.0 0
M  V30 7 C 2.5182 1.5663 0.0 0
M  V30 8 C 1.241 3.8074 0.0 0 CFG=2
M  V30 9 O -2.6989 0.0843 0.0 0
M  V30 10 C -3.9761 2.3254 0.0 0
M  V30 11 C -2.6507 4.5906 0.0 0
M  V30 12 C -0.0722 4.5906 0.0 0
M  V30 13 O 2.482 0.0963 0.0 0
M  V30 14 C 3.7833 2.3495 0.0 0 CFG=1
M  V30 15 C 2.5061 4.5906 0.0 0
M  V30 16 C -3.9881 3.8436 0.0 0
M  V30 17 ? -2.6628 6.1088 0.0 0
M  V30 18 C -0.8554 5.928 0.0 0
M  V30 19 C 0.6626 5.928 0.0 0
M  V30 20 O 3.7472 0.8795 0.0 0
M  V30 21 C 5.0485 1.6145 0.0 0
M  V30 22 C 3.7713 3.8436 0.0 0 CFG=2
M  V30 23 C 2.47 6.1329 0.0 0
M  V30 24 O 5.0123 0.1445 0.0 0
M  V30 25 C 6.3136 2.3977 0.0 0
M  V30 26 C 5.0364 4.6267 0.0 0
M  V30 27 C 6.3015 3.8797 0.0 0
M  V30 28 C 7.5787 1.6627 0.0 0
M  V30 29 N 5.0003 6.169 0.0 0
M  V30 30 O 7.5667 4.6629 0.0 0
M  V30 31 O 7.5426 0.1927 0.0 0
M  V30 32 N 8.8439 2.4459 0.0 0
M  V30 33 C 6.2654 6.9522 0.0 0
M  V30 34 C 3.6628 6.9522 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 8 4 CFG=3
M  V30 8 1 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 6 12
M  V30 12 1 7 13
M  V30 13 1 7 14
M  V30 14 1 8 15
M  V30 15 2 10 16
M  V30 16 1 11 17
M  V30 17 1 12 18
M  V30 18 1 12 19
M  V30 19 1 14 20 CFG=1
M  V30 20 1 14 21
M  V30 21 1 14 22
M  V30 22 1 15 23
M  V30 23 2 21 24
M  V30 24 1 21 25
M  V30 25 1 22 26 CFG=3
M  V30 26 2 25 27
M  V30 27 1 25 28
M  V30 28 1 26 29
M  V30 29 1 27 30
M  V30 30 2 28 31
M  V30 31 1 28 32
M  V30 32 1 29 33
M  V30 33 1 29 34
M  V30 34 1 8 12
M  V30 35 1 11 16
M  V30 36 1 15 22
M  V30 37 1 26 27
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 8 14 22)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000799A1-20220106-C00016

>  <Row No>
842

$$$$
US20220000799A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.012 -1.491 0.0 0
M  V30 3 C 1.2505 -2.2365 0.0 0
M  V30 4 C -1.3226 -2.2365 0.0 0
M  V30 5 C 2.513 -1.4429 0.0 0
M  V30 6 C 1.2384 -3.7275 0.0 0
M  V30 7 C -1.3346 -3.7275 0.0 0
M  V30 8 C -2.6333 -1.4429 0.0 0
M  V30 9 O 2.4769 0.0961 0.0 0
M  V30 10 O 3.7756 -2.1763 0.0 0
M  V30 11 N -0.0721 -4.473 0.0 0
M  V30 12 C -2.6453 -4.461 0.0 0
M  V30 13 C -3.9439 -2.1884 0.0 0
M  V30 14 C -0.1082 -5.9399 0.0 0
M  V30 15 C -3.9559 -3.6794 0.0 0
M  V30 16 C -2.6814 -5.9279 0.0 0
M  V30 17 C -5.2786 -1.4068 0.0 0
M  V30 18 N -5.2666 -4.4249 0.0 0
M  V30 19 C -5.2786 -5.9159 0.0 0
M  V30 20 C -6.5772 -3.6553 0.0 0
M  V30 21 C -6.5892 -6.6614 0.0 0
M  V30 22 C -7.8879 -4.4008 0.0 0
M  V30 23 N -7.8999 -5.8798 0.0 0
M  V30 24 ? -9.2105 -6.6253 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 3 6
M  V30 6 2 4 7
M  V30 7 1 4 8
M  V30 8 2 5 9
M  V30 9 1 5 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 2 8 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 15 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 7 11
M  V30 25 1 13 15
M  V30 26 1 22 23
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000799A1-20220106-C00017

>  <Row No>
843

$$$$
US20220000799A1-20220106-C00018
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 29 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.277 0.7638 0.0 0
M  V30 3 O 1.2412 2.2914 0.0 0
M  V30 4 C 2.554 0.0358 0.0 0 CFG=2
M  V30 5 C -0.0835 3.0553 0.0 0 CFG=2
M  V30 6 C 3.831 0.7996 0.0 0 CFG=2
M  V30 7 C 2.5182 -1.4202 0.0 0
M  V30 8 C -0.1193 4.5829 0.0 0 CFG=2
M  V30 9 C -1.4083 2.3392 0.0 0
M  V30 10 O 5.108 0.0596 0.0 0
M  V30 11 C 3.7952 2.3272 0.0 0 CFG=2
M  V30 12 O -1.4441 5.3587 0.0 0
M  V30 13 C 1.1338 5.3587 0.0 0 CFG=1
M  V30 14 C -1.4441 3.8668 0.0 0
M  V30 15 ? 6.3851 0.8235 0.0 0
M  V30 16 C 5.0484 3.0911 0.0 0 CFG=1
M  V30 17 C 2.4705 3.103 0.0 0
M  V30 18 O 2.3869 4.6426 0.0 0
M  V30 19 C 1.098 6.8863 0.0 0 CFG=1
M  V30 20 C 5.0126 4.6187 0.0 0 CFG=1
M  V30 21 C 6.3015 2.363 0.0 0
M  V30 22 C 2.375 7.6502 0.0 0
M  V30 23 C -0.2267 7.6621 0.0 0
M  V30 24 O 4.9768 6.1464 0.0 0
M  V30 25 C 3.6878 5.3945 0.0 0
M  V30 26 C 6.2657 5.3825 0.0 0
M  V30 27 O 2.3392 9.1778 0.0 0
M  V30 28 C 3.652 6.9221 0.0 0 CFG=2
M  V30 29 C 4.9052 7.686 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 4 7 CFG=3
M  V30 7 1 5 8
M  V30 8 1 5 9 CFG=1
M  V30 9 1 6 10 CFG=1
M  V30 10 1 6 11
M  V30 11 1 8 12
M  V30 12 1 8 13
M  V30 13 1 8 14 CFG=1
M  V30 14 1 10 15
M  V30 15 1 11 16
M  V30 16 1 11 17 CFG=1
M  V30 17 1 13 18 CFG=3
M  V30 18 1 13 19
M  V30 19 1 16 20
M  V30 20 1 16 21 CFG=1
M  V30 21 1 19 22
M  V30 22 1 19 23 CFG=3
M  V30 23 1 20 24 CFG=3
M  V30 24 1 20 25
M  V30 25 1 20 26
M  V30 26 2 22 27
M  V30 27 1 22 28
M  V30 28 1 28 29 CFG=1
M  V30 29 1 25 28
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(10 4 5 6 8 11 13 16 19 20 28)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00038001.cdx

>  <name>
US20220000799A1-20220106-C00018

>  <Row No>
844

$$$$
US20220000799A1-20220106-C00020
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 34 36 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.7268 -1.272 0.0 0
M  V30 3 O 0.7268 1.3447 0.0 0
M  V30 4 O -1.5506 0.0363 0.0 0
M  V30 5 F -3.8766 -2.229 0.0 0
M  V30 6 C -2.6046 -1.4295 0.0 0
M  V30 7 C -1.3325 -2.1684 0.0 0
M  V30 8 C -2.6409 0.1211 0.0 0
M  V30 9 C -0.0605 -1.381 0.0 0
M  V30 10 C -1.3689 0.9085 0.0 0
M  V30 11 C -0.0969 0.1696 0.0 0
M  V30 12 C 1.1751 0.957 0.0 0
M  V30 13 C 2.4471 0.2301 0.0 0 CFG=2
M  V30 14 N 2.4107 -1.2477 0.0 0
M  V30 15 C 3.7191 1.0176 0.0 0
M  V30 16 C 1.066 -1.9867 0.0 0
M  V30 17 O 3.6828 2.5682 0.0 0
M  V30 18 O 4.9911 0.2907 0.0 0
M  V30 19 O -0.2786 -1.1993 0.0 0
M  V30 20 O 1.0297 -3.4647 0.0 0
M  V30 21 C -0.3149 -4.1916 0.0 0
M  V30 22 C -0.3513 -5.6695 0.0 0
M  V30 23 C 0.8359 -6.5176 0.0 0
M  V30 24 C -1.6112 -6.5176 0.0 0
M  V30 25 C 0.327 -7.9228 0.0 0
M  V30 26 C 2.2775 -6.1662 0.0 0
M  V30 27 C -1.1751 -7.9228 0.0 0
M  V30 28 C -3.1255 -6.1662 0.0 0
M  V30 29 C 1.2962 -9.001 0.0 0
M  V30 30 C 3.2466 -7.2444 0.0 0
M  V30 31 C -2.2169 -9.001 0.0 0
M  V30 32 C -4.1673 -7.2444 0.0 0
M  V30 33 C 2.7378 -8.6497 0.0 0
M  V30 34 C -3.7312 -8.6497 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 5 6
M  V30 5 2 6 7
M  V30 6 1 6 8
M  V30 7 1 7 9
M  V30 8 2 8 10
M  V30 9 2 9 11
M  V30 10 1 11 12
M  V30 11 1 12 13
M  V30 12 1 13 14 CFG=1
M  V30 13 1 13 15
M  V30 14 1 14 16
M  V30 15 2 15 17
M  V30 16 1 15 18
M  V30 17 2 16 19
M  V30 18 1 16 20
M  V30 19 1 20 21
M  V30 20 1 21 22
M  V30 21 1 22 23
M  V30 22 1 22 24
M  V30 23 2 23 25
M  V30 24 1 23 26
M  V30 25 2 24 27
M  V30 26 1 24 28
M  V30 27 1 25 29
M  V30 28 2 26 30
M  V30 29 1 27 31
M  V30 30 2 28 32
M  V30 31 2 29 33
M  V30 32 2 31 34
M  V30 33 1 10 11
M  V30 34 1 25 27
M  V30 35 1 30 33
M  V30 36 1 32 34
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 13)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00040001.cdx

>  <name>
US20220000799A1-20220106-C00020

>  <Row No>
845

$$$$
US20220000799A1-20220106-C00021
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 6 3 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Y 0.0 0.0 0.0 0 VAL=1
M  V30 2 C 1.4995 0.0357 0.0 0
M  V30 3 C 2.9991 0.0714 0.0 0
M  V30 4 C 4.4987 0.1071 0.0 0
M  V30 5 C 0.6664 0.2856 0.0 0
M  V30 6 C 2.1898 0.2856 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00042001.cdx

>  <name>
US20220000799A1-20220106-C00021

>  <Row No>
846

$$$$
US20220000799A1-20220106-C00022
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 6 3 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C 1.4753 0.0362 0.0 0
M  V30 3 A -1.5479 0.0362 0.0 0
M  V30 4 C 2.9507 0.0725 0.0 0
M  V30 5 C -0.8707 0.2902 0.0 0
M  V30 6 C 0.6772 0.2902 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00043001.cdx

>  <name>
US20220000799A1-20220106-C00022

>  <Row No>
847

$$$$
US20220000799A1-20220106-C00023
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 C 0.0 0.0 0.0 0
M  V30 2 C 1.2481 0.7607 0.0 0
M  V30 3 C -1.3194 0.7607 0.0 0
M  V30 4 C 1.2124 2.2823 0.0 0
M  V30 5 C -1.3551 2.2823 0.0 0
M  V30 6 C -0.1069 3.0549 0.0 0
M  V30 7 C 1.997 1.8068 0.0 0
M  V30 8 C 0.4754 1.8425 0.0 0
M  V30 9 C 3.4472 1.8425 0.0 0
M  V30 10 C 1.9613 3.3283 0.0 0
M  V30 11 C 1.9613 0.3566 0.0 0
M  V30 12 C -1.2362 1.997 0.0 0
M  V30 13 C -2.5557 2.7697 0.0 0
M  V30 14 C -1.2362 1.6166 0.0 0
M  V30 15 C -2.5557 0.9034 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 2 4 6
M  V30 6 1 7 8
M  V30 7 1 7 9
M  V30 8 1 7 10
M  V30 9 1 7 11
M  V30 10 1 12 13
M  V30 11 1 14 15
M  V30 12 1 5 6
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00044001.cdx

>  <name>
US20220000799A1-20220106-C00023

>  <Row No>
848

$$$$
US20220000799A1-20220106-C00024
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 10 4 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Y 0.0 0.0 0.0 0 VAL=1
M  V30 2 C 1.4813 0.0364 0.0 0
M  V30 3 C 2.9626 0.0728 0.0 0
M  V30 4 C 1.1656 3.2055 0.0 0
M  V30 5 A -0.3885 3.2419 0.0 0
M  V30 6 C 2.6469 3.2419 0.0 0
M  V30 7 C 0.6799 0.2914 0.0 0
M  V30 8 C 2.137 0.2914 0.0 0
M  V30 9 C 0.5828 3.2055 0.0 0
M  V30 10 C 2.0398 3.2055 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 4 5
M  V30 4 1 4 6
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00045001.cdx

>  <name>
US20220000799A1-20220106-C00024

>  <Row No>
849

$$$$
US20220000799A1-20220106-C00025
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 7 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 S -1.2991 0.7628 0.0 0
M  V30 3 O -2.0738 2.0857 0.0 0
M  V30 4 O -0.5721 2.0857 0.0 0
M  V30 5 ? -2.5982 0.0357 0.0 0
M  V30 6 S 8.1047 1.0488 0.0 0 CFG=2
M  V30 7 O 8.0689 2.5744 0.0 0
M  V30 8 O 9.3562 0.3337 0.0 0 CHG=-1
M  V30 9 ? 6.8056 0.3098 0.0 0
M  V30 10 S -1.907 -1.4302 0.0 0
M  V30 11 S 7.5326 -1.4302 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 2 6 7
M  V30 6 1 6 8 CFG=3
M  V30 7 1 6 9
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 6)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00046001.cdx

>  <name>
US20220000799A1-20220106-C00025

>  <Row No>
850

$$$$
US20220000799A1-20220106-C00026
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 77 71 0 0 0
M  V30 BEGIN ATOM
M  V30 1 I 0.0 0.0 0.0 0
M  V30 2 C -1.5347 0.0289 0.0 0
M  V30 3 C -2.3166 -1.2451 0.0 0
M  V30 4 C -2.3745 1.4189 0.0 0
M  V30 5 C -3.9093 -1.1583 0.0 0
M  V30 6 ? -1.5926 -2.5193 0.0 0
M  V30 7 C -3.9672 1.5058 0.0 0
M  V30 8 C -4.7491 0.2316 0.0 0
M  V30 9 F -4.807 2.8958 0.0 0
M  V30 10 S 12.5099 -5.7916 0.0 0
M  V30 11 F 13.1759 -4.4016 0.0 0
M  V30 12 O 11.1199 -4.9518 0.0 0
M  V30 13 O 13.7261 -6.4576 0.0 0
M  V30 14 C 11.728 -7.0657 0.0 0
M  V30 15 C 10.1932 -7.0368 0.0 0
M  V30 16 C 12.4519 -8.3399 0.0 0
M  V30 17 C 9.4113 -8.3109 0.0 0
M  V30 18 C 11.6701 -9.614 0.0 0
M  V30 19 C 7.8186 -8.2241 0.0 0
M  V30 20 C 10.1353 -9.5851 0.0 0
M  V30 21 C 6.9789 -9.4403 0.0 0
M  V30 22 C 6.9789 -6.8341 0.0 0
M  V30 23 ? 9.3534 -10.8592 0.0 0
M  V30 24 C 5.3862 -9.3534 0.0 0
M  V30 25 ? 7.6449 -10.6565 0.0 0
M  V30 26 C 5.3862 -6.7472 0.0 0
M  V30 27 C 4.5464 -7.9634 0.0 0
M  V30 28 F 4.5464 -5.3572 0.0 0
M  V30 29 S 6.4866 -26.4098 0.0 0
M  V30 30 F 7.1526 -25.0198 0.0 0
M  V30 31 O 5.0966 -25.57 0.0 0
M  V30 32 O 7.7028 -27.0758 0.0 0
M  V30 33 C 5.6468 -27.626 0.0 0
M  V30 34 F 4.0541 -27.5391 0.0 0
M  V30 35 C 6.3128 -28.8422 0.0 0
M  V30 36 C 7.7318 -28.7554 0.0 0
M  V30 37 C 8.3978 -27.3654 0.0 0
M  V30 38 C 8.3978 -29.9716 0.0 0
M  V30 39 C 9.8168 -27.2785 0.0 0
M  V30 40 C 9.8168 -29.8847 0.0 0
M  V30 41 C 10.4828 -28.4947 0.0 0
M  V30 42 N 11.9017 -28.4079 0.0 0
M  V30 43 C 12.5678 -29.6241 0.0 0
M  V30 44 C 12.5678 -27.0179 0.0 0
M  V30 45 S 4.8649 -29.1897 0.0 0
M  V30 46 O 3.2722 -29.1029 0.0 0
M  V30 47 O 6.2839 -29.1029 0.0 0
M  V30 48 S -6.0232 -18.9965 0.0 0
M  V30 49 O -6.863 -17.6065 0.0 0
M  V30 50 O -5.3572 -20.2127 0.0 0
M  V30 51 S -3.4749 -20.3865 0.0 0
M  V30 52 O -4.3147 -21.6027 0.0 0
M  V30 53 O -2.8089 -18.9965 0.0 0
M  V30 54 S 3.9383 -7.4132 0.0 0
M  V30 55 O 3.0985 -6.0232 0.0 0
M  V30 56 O 4.6043 -8.6295 0.0 0
M  V30 57 S -6.0232 1.8533 0.0 0
M  V30 58 O -6.863 3.2433 0.0 0
M  V30 59 O -5.3572 0.637 0.0 0
M  V30 60 S -5.3282 -20.8498 0.0 0
M  V30 61 F -4.112 -21.5158 0.0 0
M  V30 62 C -6.7182 -21.5158 0.0 0
M  V30 63 H -8.1082 -20.6761 0.0 0 MASS=2
M  V30 64 F -5.0966 -17.6065 0.0 0
M  V30 65 C -4.4305 -18.8227 0.0 0
M  V30 66 F -5.2703 -20.039 0.0 0
M  V30 67 O -0.9266 -18.7648 0.0 0
M  V30 68 C 0.4922 -18.6779 0.0 0
M  V30 69 C -1.7664 -19.9811 0.0 0
M  V30 70 C 1.1583 -17.2879 0.0 0
M  V30 71 C 1.1583 -19.8942 0.0 0
M  V30 72 C 2.5772 -17.2011 0.0 0
M  V30 73 C 2.5772 -19.8073 0.0 0
M  V30 74 C 3.2433 -18.4173 0.0 0
M  V30 75 N 4.6622 -18.3304 0.0 0
M  V30 76 C 5.3282 -19.5467 0.0 0
M  V30 77 C 5.3282 -16.9405 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 7 9
M  V30 9 1 10 11
M  V30 10 2 10 12
M  V30 11 2 10 13
M  V30 12 1 10 14
M  V30 13 2 14 15
M  V30 14 1 14 16
M  V30 15 1 15 17
M  V30 16 2 16 18
M  V30 17 1 17 19
M  V30 18 2 17 20
M  V30 19 2 19 21
M  V30 20 1 19 22
M  V30 21 1 20 23
M  V30 22 1 21 24
M  V30 23 1 21 25
M  V30 24 2 22 26
M  V30 25 2 24 27
M  V30 26 1 26 28
M  V30 27 1 29 30
M  V30 28 2 29 31
M  V30 29 2 29 32
M  V30 30 1 29 33
M  V30 31 1 33 34
M  V30 32 2 33 35
M  V30 33 1 35 36
M  V30 34 2 36 37
M  V30 35 1 36 38
M  V30 36 1 37 39
M  V30 37 2 38 40
M  V30 38 2 39 41
M  V30 39 1 41 42
M  V30 40 1 42 43
M  V30 41 1 42 44
M  V30 42 2 45 46
M  V30 43 2 45 47
M  V30 44 2 48 49
M  V30 45 2 48 50
M  V30 46 2 51 52
M  V30 47 2 51 53
M  V30 48 2 54 55
M  V30 49 2 54 56
M  V30 50 2 57 58
M  V30 51 2 57 59
M  V30 52 1 60 61
M  V30 53 1 60 62
M  V30 54 1 62 63
M  V30 55 1 64 65
M  V30 56 1 65 66
M  V30 57 1 67 68
M  V30 58 1 67 69
M  V30 59 2 68 70
M  V30 60 1 68 71
M  V30 61 1 70 72
M  V30 62 2 71 73
M  V30 63 2 72 74
M  V30 64 1 74 75
M  V30 65 1 75 76
M  V30 66 1 75 77
M  V30 67 1 7 8
M  V30 68 1 18 20
M  V30 69 1 26 27
M  V30 70 1 40 41
M  V30 71 1 73 74
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00047001.cdx

>  <name>
US20220000799A1-20220106-C00026

>  <Row No>
851

$$$$
US20220000799A1-20220106-C00027
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 40 38 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.8114 -1.4697 0.0 0
M  V30 3 O 0.8114 1.5615 0.0 0
M  V30 4 O -1.7912 0.0459 0.0 0
M  V30 5 S 2.327 -13.7175 0.0 0
M  V30 6 O 3.1385 -12.1559 0.0 0
M  V30 7 F -4.4092 -2.4495 0.0 0
M  V30 8 C -3.3069 -1.7606 0.0 0
M  V30 9 C -2.2046 -2.3577 0.0 0
M  V30 10 C -3.3528 -0.398 0.0 0
M  V30 11 C -1.1023 -1.6687 0.0 0
M  V30 12 C -2.2505 0.2908 0.0 0
M  V30 13 C -1.1482 -0.3061 0.0 0
M  V30 14 C -0.0459 0.3827 0.0 0
M  V30 15 C 1.0563 -0.2143 0.0 0
M  V30 16 O 1.0104 -1.485 0.0 0
M  V30 17 N 2.1586 0.4746 0.0 0
M  V30 18 O 8.0835 -15.4322 0.0 0
M  V30 19 C 8.0376 -13.641 0.0 0
M  V30 20 N 9.5073 -12.7377 0.0 0
M  V30 21 C 6.476 -12.7377 0.0 0
M  V30 22 C 4.9144 -13.5491 0.0 0
M  V30 23 C 4.8685 -15.2485 0.0 0
M  V30 24 C 3.3528 -12.6458 0.0 0
M  V30 25 C 3.3069 -16.0599 0.0 0
M  V30 26 C 1.7912 -13.4573 0.0 0
M  V30 27 C 1.7453 -15.1566 0.0 0
M  V30 28 O 0.1837 -15.9681 0.0 0
M  V30 29 O 0.1377 -17.6675 0.0 0 CHG=-1
M  V30 30 O 14.4524 -2.0821 0.0 0
M  V30 31 C 14.4065 -0.7195 0.0 0
M  V30 32 N 15.5088 -0.0306 0.0 0
M  V30 33 C 13.2123 -0.0306 0.0 0
M  V30 34 C 12.0181 -0.6277 0.0 0
M  V30 35 C 11.9722 -1.8984 0.0 0
M  V30 36 C 10.824 0.0612 0.0 0
M  V30 37 C 10.778 -2.4954 0.0 0
M  V30 38 C 9.6298 -0.5358 0.0 0
M  V30 39 C 9.5839 -1.8065 0.0 0
M  V30 40 O 8.3897 -2.4036 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 2 5 6
M  V30 5 1 7 8
M  V30 6 2 8 9
M  V30 7 1 8 10
M  V30 8 1 9 11
M  V30 9 2 10 12
M  V30 10 2 11 13
M  V30 11 1 13 14
M  V30 12 1 14 15
M  V30 13 2 15 16
M  V30 14 1 15 17
M  V30 15 2 18 19
M  V30 16 1 19 20
M  V30 17 1 19 21
M  V30 18 1 21 22
M  V30 19 2 22 23
M  V30 20 1 22 24
M  V30 21 1 23 25
M  V30 22 2 24 26
M  V30 23 2 25 27
M  V30 24 1 27 28
M  V30 25 1 28 29
M  V30 26 2 30 31
M  V30 27 1 31 32
M  V30 28 1 31 33
M  V30 29 1 33 34
M  V30 30 2 34 35
M  V30 31 1 34 36
M  V30 32 1 35 37
M  V30 33 2 36 38
M  V30 34 2 37 39
M  V30 35 1 39 40
M  V30 36 1 12 13
M  V30 37 1 26 27
M  V30 38 1 38 39
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00049001.cdx

>  <name>
US20220000799A1-20220106-C00027

>  <Row No>
852

$$$$
US20220000799A1-20220106-C00028
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 56 54 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0362 -1.4745 0.0 0
M  V30 3 O 1.2448 -2.1876 0.0 0
M  V30 4 C -1.3899 -2.1876 0.0 0
M  V30 5 C -2.7436 -1.402 0.0 0
M  V30 6 C -1.4261 -3.6621 0.0 0
M  V30 7 C -4.0972 -2.1151 0.0 0
M  V30 8 C -2.7798 -4.3752 0.0 0
M  V30 9 F -5.4509 -1.3295 0.0 0
M  V30 10 C -4.1335 -3.5896 0.0 0
M  V30 11 S -0.7735 -12.0863 0.0 0
M  V30 12 O -2.1272 -11.2886 0.0 0
M  V30 13 O 0.5076 -12.7994 0.0 0
M  V30 14 S -5.608 -2.9007 0.0 0
M  V30 15 O -6.9617 -2.103 0.0 0
M  V30 16 O -4.3269 -3.6138 0.0 0
M  V30 17 S -6.6716 6.1882 0.0 0
M  V30 18 O -8.0253 6.9738 0.0 0
M  V30 19 O -5.3905 5.4751 0.0 0
M  V30 20 F -6.4783 7.9286 0.0 0
M  V30 21 C -5.1971 7.2155 0.0 0
M  V30 22 C -3.9159 8.0132 0.0 0
M  V30 23 C -5.2334 5.741 0.0 0
M  V30 24 C -2.6348 7.3001 0.0 0
M  V30 25 C -3.9522 5.0279 0.0 0
M  V30 26 C -1.3536 8.0978 0.0 0
M  V30 27 C -2.671 5.8256 0.0 0
M  V30 28 O -1.3899 9.6449 0.0 0
M  V30 29 O -0.0725 7.3847 0.0 0
M  V30 30 F -0.6768 -10.4426 0.0 0
M  V30 31 C 0.6043 -11.1557 0.0 0
M  V30 32 C 1.8854 -10.3701 0.0 0
M  V30 33 C 0.568 -12.6302 0.0 0
M  V30 34 C 3.1666 -11.0832 0.0 0
M  V30 35 C 1.8492 -13.3433 0.0 0
M  V30 36 C 4.4477 -10.2976 0.0 0
M  V30 37 C 3.1303 -12.5577 0.0 0
M  V30 38 O 4.4115 -8.7505 0.0 0
M  V30 39 N 5.7289 -11.0107 0.0 0
M  V30 40 C 7.0101 -10.225 0.0 0
M  V30 41 C 8.2912 -10.9381 0.0 0
M  V30 42 C 6.9738 -8.678 0.0 0
M  V30 43 C 9.5724 -10.1525 0.0 0
M  V30 44 C 8.255 -7.8924 0.0 0
M  V30 45 C 10.8535 -10.8656 0.0 0
M  V30 46 C 9.5361 -8.6055 0.0 0
M  V30 47 C 12.1347 -11.5787 0.0 0
M  V30 48 N 4.1577 -1.1602 0.0 0
M  V30 49 C 5.4388 -0.3625 0.0 0
M  V30 50 C 6.72 -1.0756 0.0 0
M  V30 51 C 5.4026 1.1844 0.0 0
M  V30 52 C 8.0011 -0.2779 0.0 0
M  V30 53 C 6.6837 1.9821 0.0 0
M  V30 54 C 9.2823 -0.991 0.0 0
M  V30 55 C 7.9649 1.269 0.0 0
M  V30 56 C 10.5635 -1.7041 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 2 7 10
M  V30 10 2 11 12
M  V30 11 2 11 13
M  V30 12 2 14 15
M  V30 13 2 14 16
M  V30 14 2 17 18
M  V30 15 2 17 19
M  V30 16 1 20 21
M  V30 17 2 21 22
M  V30 18 1 21 23
M  V30 19 1 22 24
M  V30 20 2 23 25
M  V30 21 1 24 26
M  V30 22 2 24 27
M  V30 23 2 26 28
M  V30 24 1 26 29
M  V30 25 1 30 31
M  V30 26 2 31 32
M  V30 27 1 31 33
M  V30 28 1 32 34
M  V30 29 2 33 35
M  V30 30 1 34 36
M  V30 31 2 34 37
M  V30 32 2 36 38
M  V30 33 1 36 39
M  V30 34 1 39 40
M  V30 35 2 40 41
M  V30 36 1 40 42
M  V30 37 1 41 43
M  V30 38 2 42 44
M  V30 39 1 43 45
M  V30 40 2 43 46
M  V30 41 3 45 47
M  V30 42 1 48 49
M  V30 43 2 49 50
M  V30 44 1 49 51
M  V30 45 1 50 52
M  V30 46 2 51 53
M  V30 47 1 52 54
M  V30 48 2 52 55
M  V30 49 3 54 56
M  V30 50 1 8 10
M  V30 51 1 25 27
M  V30 52 1 35 37
M  V30 53 1 44 46
M  V30 54 1 53 55
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00050001.cdx

>  <name>
US20220000799A1-20220106-C00028

>  <Row No>
853

$$$$
US20220000799A1-20220106-C00029
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 89 97 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 S -0.0659 1.671 0.0 0
M  V30 3 O 1.4731 1.737 0.0 0
M  V30 4 O -1.737 1.737 0.0 0
M  V30 5 C -0.1319 3.3421 0.0 0
M  V30 6 C -1.5831 4.1996 0.0 0
M  V30 7 C 1.1873 4.1996 0.0 0
M  V30 8 C -1.649 5.8707 0.0 0
M  V30 9 C 1.1213 5.8707 0.0 0
M  V30 10 C -0.3298 6.7283 0.0 0
M  V30 11 C -0.3957 8.3993 0.0 0
M  V30 12 C 0.9234 9.2569 0.0 0
M  V30 13 S -0.5277 -12.1373 0.0 0
M  V30 14 F -0.5936 -13.6765 0.0 0
M  V30 15 O 1.0114 -12.0713 0.0 0
M  V30 16 O -2.1987 -12.0713 0.0 0
M  V30 17 C -0.5936 -10.6641 0.0 0
M  V30 18 C -1.8689 -9.8945 0.0 0
M  V30 19 C 0.5496 -9.8945 0.0 0
M  V30 20 C -1.9349 -8.4213 0.0 0
M  V30 21 C 0.4837 -8.4213 0.0 0
M  V30 22 C -0.7915 -7.6518 0.0 0
M  V30 23 C -0.8575 -6.1786 0.0 0
M  V30 24 C 0.2858 -5.409 0.0 0
M  V30 25 S -0.1759 -19.7011 0.0 0
M  V30 26 O -1.715 -19.0195 0.0 0
M  V30 27 O 1.2313 -20.2508 0.0 0
M  V30 28 F -0.3518 -17.9421 0.0 0
M  V30 29 C 0.9015 -18.4258 0.0 0
M  V30 30 C 1.9789 -17.5024 0.0 0
M  V30 31 C 1.0114 -19.7891 0.0 0
M  V30 32 C 3.2322 -17.9861 0.0 0
M  V30 33 C 2.2647 -20.2728 0.0 0
M  V30 34 C 3.3421 -19.3274 0.0 0
M  V30 35 C 4.5954 -19.8111 0.0 0
M  V30 36 N 4.6834 -21.1743 0.0 0
M  V30 37 C 4.3756 -23.9008 0.0 0
M  V30 38 C 5.0792 -22.6255 0.0 0
M  V30 39 C 5.5849 -24.4725 0.0 0
M  V30 40 C 2.9683 -24.2527 0.0 0
M  V30 41 C 6.2665 -23.2412 0.0 0
M  V30 42 C 3.6719 -23.0213 0.0 0
M  V30 43 C 6.7502 -25.5499 0.0 0
M  V30 44 N 8.0475 -25.0442 0.0 0
M  V30 45 N 8.4213 -23.615 0.0 0
M  V30 46 C 9.1249 -25.8138 0.0 0
M  V30 47 N 9.8066 -23.549 0.0 0
M  V30 48 C 10.2024 -24.9123 0.0 0
M  V30 49 C 11.4996 -25.2861 0.0 0
M  V30 50 O 12.4891 -24.2746 0.0 0
M  V30 51 C 13.7864 -24.6484 0.0 0
M  V30 52 C 14.0063 -25.9677 0.0 0
M  V30 53 C 14.7758 -23.637 0.0 0
M  V30 54 C 15.3036 -26.3415 0.0 0
M  V30 55 C 12.8849 -26.8472 0.0 0
M  V30 56 C 16.0731 -24.0108 0.0 0
M  V30 57 N 16.293 -25.3301 0.0 0
M  V30 58 C 15.5234 -27.6608 0.0 0
M  V30 59 C 13.1048 -28.1665 0.0 0
M  V30 60 O 17.0626 -22.9993 0.0 0
M  V30 61 C 17.5903 -25.7039 0.0 0
M  V30 62 C 14.4021 -28.5403 0.0 0
M  V30 63 O 17.4144 -3.1662 0.0 0
M  V30 64 C 16.315 -4.0457 0.0 0
M  V30 65 N 16.5349 -5.343 0.0 0
M  V30 66 C 14.9298 -3.54 0.0 0
M  V30 67 C 15.4355 -6.2225 0.0 0
M  V30 68 C 17.7882 -5.7168 0.0 0
M  V30 69 C 13.8304 -4.4195 0.0 0
M  V30 70 C 14.0502 -5.7168 0.0 0
M  V30 71 C 15.6554 -7.5198 0.0 0
M  V30 72 O 12.4451 -3.9138 0.0 0
M  V30 73 C 12.9508 -6.5963 0.0 0
M  V30 74 C 14.556 -8.3993 0.0 0
M  V30 75 C 11.3457 -4.7933 0.0 0
M  V30 76 C 13.1707 -7.8936 0.0 0
M  V30 77 C 9.9605 -4.2876 0.0 0
M  V30 78 N 9.4548 -2.9024 0.0 0
M  V30 79 C 8.7731 -5.0352 0.0 0
M  V30 80 N 7.9816 -2.8364 0.0 0
M  V30 81 N 7.5858 -4.1557 0.0 0
M  V30 82 C 6.2006 -4.5295 0.0 0
M  V30 83 C 4.9252 -3.1882 0.0 0
M  V30 84 C 5.5849 -2.1328 0.0 0
M  V30 85 C 3.606 -2.6825 0.0 0
M  V30 86 C 4.2876 -1.4072 0.0 0
M  V30 87 C 3.7599 0.1319 0.0 0
M  V30 88 C 2.1987 -3.0123 0.0 0
M  V30 89 C 2.9024 -1.781 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 2 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 2 8 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 1 13 14
M  V30 13 2 13 15
M  V30 14 2 13 16
M  V30 15 1 13 17
M  V30 16 2 17 18
M  V30 17 1 17 19
M  V30 18 1 18 20
M  V30 19 2 19 21
M  V30 20 2 20 22
M  V30 21 1 22 23
M  V30 22 1 23 24
M  V30 23 2 25 26
M  V30 24 2 25 27
M  V30 25 1 28 29
M  V30 26 2 29 30
M  V30 27 1 29 31
M  V30 28 1 30 32
M  V30 29 2 31 33
M  V30 30 2 32 34
M  V30 31 1 34 35
M  V30 32 1 35 36
M  V30 33 1 36 37
M  V30 34 1 36 38
M  V30 35 1 37 39
M  V30 36 1 37 40
M  V30 37 1 38 41
M  V30 38 1 38 42
M  V30 39 1 39 43
M  V30 40 1 43 44
M  V30 41 1 44 45
M  V30 42 1 44 46
M  V30 43 2 45 47
M  V30 44 2 46 48
M  V30 45 1 48 49
M  V30 46 1 49 50
M  V30 47 1 50 51
M  V30 48 1 51 52
M  V30 49 2 51 53
M  V30 50 2 52 54
M  V30 51 1 52 55
M  V30 52 1 53 56
M  V30 53 1 54 57
M  V30 54 1 54 58
M  V30 55 2 55 59
M  V30 56 2 56 60
M  V30 57 1 57 61
M  V30 58 2 58 62
M  V30 59 2 63 64
M  V30 60 1 64 65
M  V30 61 1 64 66
M  V30 62 1 65 67
M  V30 63 1 65 68
M  V30 64 2 66 69
M  V30 65 2 67 70
M  V30 66 1 67 71
M  V30 67 1 69 72
M  V30 68 1 70 73
M  V30 69 2 71 74
M  V30 70 1 72 75
M  V30 71 2 73 76
M  V30 72 1 75 77
M  V30 73 1 77 78
M  V30 74 2 77 79
M  V30 75 2 78 80
M  V30 76 1 79 81
M  V30 77 1 81 82
M  V30 78 1 82 83
M  V30 79 1 82 84
M  V30 80 1 83 85
M  V30 81 1 84 86
M  V30 82 1 85 87
M  V30 83 1 85 88
M  V30 84 1 86 89
M  V30 85 1 9 10
M  V30 86 1 21 22
M  V30 87 1 33 34
M  V30 88 1 40 42
M  V30 89 1 41 43
M  V30 90 1 47 48
M  V30 91 1 56 57
M  V30 92 1 59 62
M  V30 93 1 69 70
M  V30 94 1 74 76
M  V30 95 1 80 81
M  V30 96 1 86 87
M  V30 97 1 88 89
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00051001.cdx

>  <name>
US20220000799A1-20220106-C00029

>  <Row No>
854

$$$$
US20220000799A1-20220106-C00030
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0 CFG=2
M  V30 2 F 1.2602 -0.7057 0.0 0
M  V30 3 O -0.7813 1.3358 0.0 0
M  V30 4 N 1.0334 1.0586 0.0 0
M  V30 5 C -1.3358 -0.7057 0.0 0
M  V30 6 ? 2.4575 0.6931 0.0 0
M  V30 7 C -2.6717 0.0756 0.0 0
M  V30 8 C -1.3737 -2.155 0.0 0
M  V30 9 C -4.0076 -0.6301 0.0 0
M  V30 10 C -2.7096 -2.8608 0.0 0
M  V30 11 C -4.0455 -2.0794 0.0 0
M  V30 12 S 12.7036 0.3024 0.0 0
M  V30 13 O 11.9222 1.6383 0.0 0
M  V30 14 O 13.4093 1.6383 0.0 0
M  V30 15 N 13.9891 -0.4284 0.0 0
M  V30 16 C 11.3677 -0.4032 0.0 0
M  V30 17 ? 15.2745 0.3276 0.0 0
M  V30 18 C 10.0318 0.378 0.0 0
M  V30 19 C 11.3299 -1.8526 0.0 0
M  V30 20 C 8.6959 -0.3276 0.0 0
M  V30 21 C 9.994 -2.5583 0.0 0
M  V30 22 C 8.6581 -1.7769 0.0 0
M  V30 23 H 4.3353 -0.7057 0.0 0 MASS=3
M  V30 24 ? 5.8098 -0.6931 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2 CFG=3
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 1 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 2 9 11
M  V30 11 2 12 13
M  V30 12 2 12 14
M  V30 13 1 12 15
M  V30 14 1 12 16
M  V30 15 1 15 17
M  V30 16 2 16 18
M  V30 17 1 16 19
M  V30 18 1 18 20
M  V30 19 2 19 21
M  V30 20 2 20 22
M  V30 21 1 23 24
M  V30 22 1 10 11
M  V30 23 1 21 22
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 1)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00052001.cdx

>  <name>
US20220000799A1-20220106-C00030

>  <Row No>
855

$$$$
US20220000799A1-20220106-C00031
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 9 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 F 1.4606 0.0521 0.0 0
M  V30 3 O -0.0521 1.5649 0.0 0
M  V30 4 O -0.0521 -1.4606 0.0 0
M  V30 5 ? -1.5301 0.0173 0.0 0
M  V30 6 S -17.8057 6.2598 0.0 0
M  V30 7 O -17.8578 4.7992 0.0 0
M  V30 8 O -17.8578 7.8247 0.0 0
M  V30 9 O -16.3451 6.3119 0.0 0 CHG=-1
M  V30 10 ? -19.3359 6.2772 0.0 0
M  V30 11 Na -15.4409 7.3726 0.0 0 CHG=1
M  V30 12 C -13.076 0.4173 0.0 0
M  V30 13 C -11.6154 0.4694 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 1 5
M  V30 5 2 6 7
M  V30 6 2 6 8
M  V30 7 1 6 9
M  V30 8 1 6 10
M  V30 9 1 12 13
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00053001.cdx

>  <name>
US20220000799A1-20220106-C00031

>  <Row No>
856

$$$$
US20220000799A1-20220106-C00032
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 33 32 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 S -1.3021 0.7645 0.0 0
M  V30 3 O -2.0905 2.0905 0.0 0
M  V30 4 N -0.5614 2.0666 0.0 0
M  V30 5 C -2.6281 0.0477 0.0 0
M  V30 6 ? 0.9198 2.0785 0.0 0
M  V30 7 C -3.9541 0.8362 0.0 0
M  V30 8 C -2.6639 -1.4096 0.0 0
M  V30 9 C -5.2801 0.1194 0.0 0
M  V30 10 C -3.9899 -2.1263 0.0 0
M  V30 11 C -5.3159 -1.3379 0.0 0
M  V30 12 S 11.8504 1.0512 0.0 0
M  V30 13 F 13.1047 0.3344 0.0 0
M  V30 14 O 11.0619 2.3772 0.0 0
M  V30 15 N 12.591 2.3533 0.0 0
M  V30 16 C 10.5244 0.3344 0.0 0
M  V30 17 ? 14.0723 2.3653 0.0 0
M  V30 18 C 9.1984 1.1229 0.0 0
M  V30 19 C 10.4885 -1.1229 0.0 0
M  V30 20 C 7.8723 0.4061 0.0 0
M  V30 21 C 9.1625 -1.8396 0.0 0
M  V30 22 C 7.8365 -1.0512 0.0 0
M  V30 23 S -1.8157 11.277 0.0 0
M  V30 24 O -1.8516 12.806 0.0 0
M  V30 25 C -3.1417 10.5602 0.0 0
M  V30 26 C -0.5614 10.5602 0.0 0
M  V30 27 C -4.4677 11.3486 0.0 0
M  V30 28 C -3.1776 9.1028 0.0 0
M  V30 29 C -5.7937 10.6319 0.0 0
M  V30 30 C -4.5036 8.386 0.0 0
M  V30 31 C -5.8296 9.1745 0.0 0
M  V30 32 N 2.867 9.7479 0.0 0
M  V30 33 C 4.3244 9.7837 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 2 9 11
M  V30 11 1 12 13
M  V30 12 2 12 14
M  V30 13 2 12 15
M  V30 14 1 12 16
M  V30 15 1 15 17
M  V30 16 2 16 18
M  V30 17 1 16 19
M  V30 18 1 18 20
M  V30 19 2 19 21
M  V30 20 2 20 22
M  V30 21 2 23 24
M  V30 22 1 23 25
M  V30 23 1 23 26
M  V30 24 2 25 27
M  V30 25 1 25 28
M  V30 26 1 27 29
M  V30 27 2 28 30
M  V30 28 2 29 31
M  V30 29 1 32 33
M  V30 30 1 10 11
M  V30 31 1 21 22
M  V30 32 1 30 31
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00054001.cdx

>  <name>
US20220000799A1-20220106-C00032

>  <Row No>
857

$$$$
US20220000799A1-20220106-C00033
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 S -1.3391 -0.7014 0.0 0
M  V30 3 O -2.117 0.6376 0.0 0
M  V30 4 O -0.6376 -1.964 0.0 0
M  V30 5 C -2.6782 -1.4028 0.0 0
M  V30 6 C -4.0173 -0.6249 0.0 0
M  V30 7 Cl -5.3564 -1.3263 0.0 0
M  V30 8 Cl -3.775 -6.6318 0.0 0
M  V30 9 C -2.5124 -5.8538 0.0 0
M  V30 10 C -1.2498 -6.5553 0.0 0
M  V30 11 S 0.0127 -5.7773 0.0 0
M  V30 12 F 1.2753 -4.9993 0.0 0
M  V30 13 O -0.7652 -4.4382 0.0 0
M  V30 14 O 0.7141 -7.0399 0.0 0
M  V30 15 S 12.8555 -5.7135 0.0 0
M  V30 16 F 14.1181 -4.9356 0.0 0
M  V30 17 O 12.0776 -4.3744 0.0 0
M  V30 18 O 13.557 -6.9762 0.0 0
M  V30 19 C 11.5164 -6.415 0.0 0
M  V30 20 C 10.1773 -5.637 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 8 9
M  V30 8 1 9 10
M  V30 9 1 10 11
M  V30 10 1 11 12
M  V30 11 2 11 13
M  V30 12 2 11 14
M  V30 13 1 15 16
M  V30 14 2 15 17
M  V30 15 2 15 18
M  V30 16 1 15 19
M  V30 17 2 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00055001.cdx

>  <name>
US20220000799A1-20220106-C00033

>  <Row No>
858

$$$$
US20220000799A1-20220106-C00034
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 13 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 F 1.2676 -0.7065 0.0 0
M  V30 3 O 0.7065 1.3299 0.0 0
M  V30 4 O -0.7688 -1.2676 0.0 0
M  V30 5 C -1.3299 0.7688 0.0 0
M  V30 6 C -2.6598 0.0623 0.0 0
M  V30 7 S 10.2239 0.0831 0.0 0
M  V30 8 F 11.4915 -0.6234 0.0 0
M  V30 9 O 10.9304 1.413 0.0 0
M  V30 10 O 9.455 -1.1844 0.0 0
M  V30 11 C 8.8939 0.8519 0.0 0
M  V30 12 C 7.564 0.1454 0.0 0
M  V30 13 C 6.2341 0.9143 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 1 5
M  V30 5 2 5 6
M  V30 6 1 7 8
M  V30 7 2 7 9
M  V30 8 2 7 10
M  V30 9 1 7 11
M  V30 10 1 11 12
M  V30 11 1 12 13
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00056001.cdx

>  <name>
US20220000799A1-20220106-C00034

>  <Row No>
859

$$$$
US20220000799A1-20220106-C00035
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 42 43 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.7192 -1.2586 0.0 0
M  V30 3 O 0.7192 1.3305 0.0 0
M  V30 4 O -1.5343 0.0359 0.0 0
M  V30 5 S 6.5208 -3.7398 0.0 0
M  V30 6 F 6.4848 -5.2022 0.0 0
M  V30 7 O 7.9832 -3.7039 0.0 0
M  V30 8 O 4.9865 -3.7039 0.0 0
M  V30 9 O 6.4848 -2.2055 0.0 0
M  V30 10 C 5.1543 -1.4264 0.0 0
M  V30 11 C 3.8237 -2.1576 0.0 0
M  V30 12 C 5.1183 0.1078 0.0 0
M  V30 13 C 2.4932 -1.3904 0.0 0
M  V30 14 C 3.7878 0.875 0.0 0
M  V30 15 C 2.4572 0.1438 0.0 0
M  V30 16 C 1.1267 0.9109 0.0 0
M  V30 17 C -0.2037 0.1917 0.0 0
M  V30 18 C 0.3476 2.2415 0.0 0
M  V30 19 C 1.8579 2.2415 0.0 0
M  V30 20 C -0.2397 -1.2706 0.0 0
M  V30 21 C -1.5343 0.9589 0.0 0
M  V30 22 C -1.5702 -2.0017 0.0 0
M  V30 23 C -2.8648 0.2397 0.0 0
M  V30 24 C -2.9008 -1.2346 0.0 0
M  V30 25 F -4.2313 -1.9658 0.0 0
M  V30 26 O -11.1237 6.0413 0.0 0
M  V30 27 C -9.8651 6.8085 0.0 0
M  V30 28 C -8.6065 6.0893 0.0 0
M  V30 29 C -9.9011 8.3428 0.0 0
M  V30 30 C -7.3479 6.8564 0.0 0
M  V30 31 C -8.6424 9.1219 0.0 0
M  V30 32 C -7.3838 8.3907 0.0 0
M  V30 33 C -6.1252 9.1699 0.0 0
M  V30 34 C -4.8666 8.4507 0.0 0
M  V30 35 C -6.8924 10.5004 0.0 0
M  V30 36 C -5.406 10.5004 0.0 0
M  V30 37 C -4.9026 6.9883 0.0 0
M  V30 38 C -3.608 9.2298 0.0 0
M  V30 39 C -3.6439 6.2691 0.0 0
M  V30 40 C -2.3494 8.5106 0.0 0
M  V30 41 C -2.3853 7.0362 0.0 0
M  V30 42 O -1.1267 6.317 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 5 6
M  V30 5 2 5 7
M  V30 6 2 5 8
M  V30 7 1 5 9
M  V30 8 1 9 10
M  V30 9 2 10 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 2 12 14
M  V30 13 2 13 15
M  V30 14 1 15 16
M  V30 15 1 16 17
M  V30 16 1 16 18
M  V30 17 1 16 19
M  V30 18 2 17 20
M  V30 19 1 17 21
M  V30 20 1 20 22
M  V30 21 2 21 23
M  V30 22 2 22 24
M  V30 23 1 24 25
M  V30 24 1 26 27
M  V30 25 2 27 28
M  V30 26 1 27 29
M  V30 27 1 28 30
M  V30 28 2 29 31
M  V30 29 2 30 32
M  V30 30 1 32 33
M  V30 31 1 33 34
M  V30 32 1 33 35
M  V30 33 1 33 36
M  V30 34 2 34 37
M  V30 35 1 34 38
M  V30 36 1 37 39
M  V30 37 2 38 40
M  V30 38 2 39 41
M  V30 39 1 41 42
M  V30 40 1 14 15
M  V30 41 1 23 24
M  V30 42 1 31 32
M  V30 43 1 40 41
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00057001.cdx

>  <name>
US20220000799A1-20220106-C00035

>  <Row No>
860

$$$$
US20220000799A1-20220106-C00037
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 34 36 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.7268 -1.272 0.0 0
M  V30 3 O 0.7268 1.3447 0.0 0
M  V30 4 O -1.5506 0.0363 0.0 0
M  V30 5 F -3.8766 -2.229 0.0 0
M  V30 6 C -2.6046 -1.4295 0.0 0
M  V30 7 C -1.3325 -2.1684 0.0 0
M  V30 8 C -2.6409 0.1211 0.0 0
M  V30 9 C -0.0605 -1.381 0.0 0
M  V30 10 C -1.3689 0.9085 0.0 0
M  V30 11 C -0.0969 0.1696 0.0 0
M  V30 12 C 1.1751 0.957 0.0 0
M  V30 13 C 2.4471 0.2301 0.0 0 CFG=2
M  V30 14 N 2.4107 -1.2477 0.0 0
M  V30 15 C 3.7191 1.0176 0.0 0
M  V30 16 C 1.066 -1.9867 0.0 0
M  V30 17 O 3.6828 2.5682 0.0 0
M  V30 18 O 4.9911 0.2907 0.0 0
M  V30 19 O -0.2786 -1.1993 0.0 0
M  V30 20 O 1.0297 -3.4647 0.0 0
M  V30 21 C -0.3149 -4.1916 0.0 0
M  V30 22 C -0.3513 -5.6695 0.0 0
M  V30 23 C 0.8359 -6.5176 0.0 0
M  V30 24 C -1.6112 -6.5176 0.0 0
M  V30 25 C 0.327 -7.9228 0.0 0
M  V30 26 C 2.2775 -6.1662 0.0 0
M  V30 27 C -1.1751 -7.9228 0.0 0
M  V30 28 C -3.1255 -6.1662 0.0 0
M  V30 29 C 1.2962 -9.001 0.0 0
M  V30 30 C 3.2466 -7.2444 0.0 0
M  V30 31 C -2.2169 -9.001 0.0 0
M  V30 32 C -4.1673 -7.2444 0.0 0
M  V30 33 C 2.7378 -8.6497 0.0 0
M  V30 34 C -3.7312 -8.6497 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 5 6
M  V30 5 2 6 7
M  V30 6 1 6 8
M  V30 7 1 7 9
M  V30 8 2 8 10
M  V30 9 2 9 11
M  V30 10 1 11 12
M  V30 11 1 12 13
M  V30 12 1 13 14 CFG=1
M  V30 13 1 13 15
M  V30 14 1 14 16
M  V30 15 2 15 17
M  V30 16 1 15 18
M  V30 17 2 16 19
M  V30 18 1 16 20
M  V30 19 1 20 21
M  V30 20 1 21 22
M  V30 21 1 22 23
M  V30 22 1 22 24
M  V30 23 2 23 25
M  V30 24 1 23 26
M  V30 25 2 24 27
M  V30 26 1 24 28
M  V30 27 1 25 29
M  V30 28 2 26 30
M  V30 29 1 27 31
M  V30 30 2 28 32
M  V30 31 2 29 33
M  V30 32 2 31 34
M  V30 33 1 10 11
M  V30 34 1 25 27
M  V30 35 1 30 33
M  V30 36 1 32 34
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 13)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00061001.cdx

>  <name>
US20220000799A1-20220106-C00037

>  <Row No>
861

$$$$
US20220000799A1-20220106-C00038
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 64 69 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.7381 -1.2705 0.0 0
M  V30 3 O 0.7381 1.3431 0.0 0
M  V30 4 O -1.5489 0.0363 0.0 0
M  V30 5 F -3.8722 -2.2265 0.0 0
M  V30 6 C -2.6016 -1.4521 0.0 0
M  V30 7 C -1.331 -2.1781 0.0 0
M  V30 8 C -2.6379 0.0968 0.0 0
M  V30 9 C -0.0605 -1.3915 0.0 0
M  V30 10 C -1.3673 0.8712 0.0 0
M  V30 11 C -0.0968 0.1573 0.0 0
M  V30 12 C 1.1737 0.9438 0.0 0
M  V30 13 C 2.4443 0.2178 0.0 0 CFG=2
M  V30 14 N 2.408 -1.2584 0.0 0
M  V30 15 C 3.7149 0.9922 0.0 0
M  V30 16 C 1.0648 -1.9845 0.0 0
M  V30 17 O 3.6786 2.5411 0.0 0
M  V30 18 O 4.9855 0.2662 0.0 0
M  V30 19 O -0.2783 -1.1979 0.0 0
M  V30 20 O 1.0285 -3.4608 0.0 0
M  V30 21 C -0.3146 -4.1989 0.0 0
M  V30 22 C -0.3509 -5.6752 0.0 0
M  V30 23 C 0.8349 -6.5223 0.0 0
M  V30 24 C -1.6094 -6.5223 0.0 0
M  V30 25 C 0.3267 -7.926 0.0 0
M  V30 26 C 2.2749 -6.1714 0.0 0
M  V30 27 C -1.1737 -7.926 0.0 0
M  V30 28 C -3.122 -6.1714 0.0 0
M  V30 29 C 1.2947 -9.003 0.0 0
M  V30 30 C 3.243 -7.2484 0.0 0
M  V30 31 C -2.2144 -9.003 0.0 0
M  V30 32 C -4.1626 -7.2484 0.0 0
M  V30 33 C 2.7347 -8.6521 0.0 0
M  V30 34 C -3.727 -8.6521 0.0 0
M  V30 35 O -9.5838 6.0988 0.0 0
M  V30 36 C -8.3132 5.3727 0.0 0
M  V30 37 O -8.3495 3.8964 0.0 0
M  V30 38 N -7.0426 6.1593 0.0 0
M  V30 39 C -9.6927 3.1704 0.0 0
M  V30 40 C -7.0789 7.7082 0.0 0 CFG=2
M  V30 41 C -9.729 1.6941 0.0 0
M  V30 42 C -5.8084 8.4947 0.0 0
M  V30 43 C -8.4221 8.4947 0.0 0
M  V30 44 C -8.5431 0.847 0.0 0
M  V30 45 C -10.9875 0.847 0.0 0
M  V30 46 O -5.8447 10.0436 0.0 0
M  V30 47 O -4.5378 7.7687 0.0 0
M  V30 48 C -9.7653 7.7687 0.0 0
M  V30 49 C -9.0514 -0.5566 0.0 0
M  V30 50 C -7.1031 1.1979 0.0 0
M  V30 51 C -10.5519 -0.5566 0.0 0
M  V30 52 C -12.5001 1.1979 0.0 0
M  V30 53 C -9.8016 6.2924 0.0 0
M  V30 54 C -11.1085 8.5552 0.0 0
M  V30 55 C -8.0833 -1.6336 0.0 0
M  V30 56 C -6.1351 0.121 0.0 0
M  V30 57 C -11.5926 -1.6336 0.0 0
M  V30 58 C -13.5408 0.121 0.0 0
M  V30 59 C -11.1448 5.5663 0.0 0
M  V30 60 C -12.4517 7.8292 0.0 0
M  V30 61 C -6.6433 -1.2826 0.0 0
M  V30 62 C -13.1052 -1.2826 0.0 0
M  V30 63 C -12.488 6.3408 0.0 0
M  V30 64 O -13.8312 5.6147 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 5 6
M  V30 5 2 6 7
M  V30 6 1 6 8
M  V30 7 1 7 9
M  V30 8 2 8 10
M  V30 9 2 9 11
M  V30 10 1 11 12
M  V30 11 1 12 13
M  V30 12 1 13 14 CFG=1
M  V30 13 1 13 15
M  V30 14 1 14 16
M  V30 15 2 15 17
M  V30 16 1 15 18
M  V30 17 2 16 19
M  V30 18 1 16 20
M  V30 19 1 20 21
M  V30 20 1 21 22
M  V30 21 1 22 23
M  V30 22 1 22 24
M  V30 23 2 23 25
M  V30 24 1 23 26
M  V30 25 2 24 27
M  V30 26 1 24 28
M  V30 27 1 25 29
M  V30 28 2 26 30
M  V30 29 1 27 31
M  V30 30 2 28 32
M  V30 31 2 29 33
M  V30 32 2 31 34
M  V30 33 2 35 36
M  V30 34 1 36 37
M  V30 35 1 36 38
M  V30 36 1 37 39
M  V30 37 1 40 38 CFG=1
M  V30 38 1 39 41
M  V30 39 1 40 42
M  V30 40 1 40 43
M  V30 41 1 41 44
M  V30 42 1 41 45
M  V30 43 2 42 46
M  V30 44 1 42 47
M  V30 45 1 43 48
M  V30 46 2 44 49
M  V30 47 1 44 50
M  V30 48 2 45 51
M  V30 49 1 45 52
M  V30 50 2 48 53
M  V30 51 1 48 54
M  V30 52 1 49 55
M  V30 53 2 50 56
M  V30 54 1 51 57
M  V30 55 2 52 58
M  V30 56 1 53 59
M  V30 57 2 54 60
M  V30 58 2 55 61
M  V30 59 2 57 62
M  V30 60 2 59 63
M  V30 61 1 63 64
M  V30 62 1 10 11
M  V30 63 1 25 27
M  V30 64 1 30 33
M  V30 65 1 32 34
M  V30 66 1 49 51
M  V30 67 1 56 61
M  V30 68 1 58 62
M  V30 69 1 60 63
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 13 40)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00062001.cdx

>  <name>
US20220000799A1-20220106-C00038

>  <Row No>
862

$$$$
US20220000799A1-20220106-C00039
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 44 36 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Y 0.0 0.0 0.0 0 VAL=3
M  V30 2 O -0.0727 1.3828 0.0 0
M  V30 3 C -1.3828 0.0727 0.0 0
M  V30 4 C 1.2373 0.0727 0.0 0
M  V30 5 S -0.1455 2.7657 0.0 0
M  V30 6 N -3.9302 0.1213 0.0 0
M  V30 7 C 3.4693 0.1455 0.0 0
M  V30 8 F -0.2183 4.1486 0.0 0
M  V30 9 O -1.5284 2.8385 0.0 0
M  V30 10 O 1.0917 2.8385 0.0 0
M  V30 11 O 3.3965 1.5284 0.0 0
M  V30 12 N 4.7066 0.2183 0.0 0
M  V30 13 Y -7.5694 7.9576 0.0 0 VAL=3
M  V30 14 O -7.6422 9.3404 0.0 0
M  V30 15 C -8.9523 8.0303 0.0 0
M  V30 16 C -6.3321 8.0303 0.0 0
M  V30 17 S -7.7149 10.7233 0.0 0
M  V30 18 N -11.4997 8.0789 0.0 0
M  V30 19 C -4.1001 8.1031 0.0 0
M  V30 20 F -7.7877 12.1062 0.0 0
M  V30 21 O -9.0978 10.7961 0.0 0
M  V30 22 O -6.4776 10.7961 0.0 0
M  V30 23 O -4.1728 9.486 0.0 0
M  V30 24 C -2.8627 8.1759 0.0 0
M  V30 25 C -1.6254 8.2487 0.0 0
M  V30 26 F -4.8521 24.2609 0.0 0
M  V30 27 C -6.0652 24.9888 0.0 0
M  V30 28 H -7.2782 24.4065 0.0 0 MASS=2
M  V30 29 O -5.6285 15.7211 0.0 0
M  V30 30 C -5.7013 14.4838 0.0 0
M  V30 31 C -4.464 14.5565 0.0 0
M  V30 32 A -8.0789 15.2116 0.0 0
M  V30 33 C -3.2267 14.6293 0.0 0
M  V30 34 O -6.0167 19.991 0.0 0
M  V30 35 C -6.0895 18.7537 0.0 0
M  V30 36 C -4.8521 18.8265 0.0 0
M  V30 37 A -8.467 19.4815 0.0 0
M  V30 38 C -3.6148 18.8993 0.0 0
M  V30 39 N -9.1221 14.3625 0.0 0
M  V30 40 A -7.8848 13.7802 0.0 0
M  V30 41 N -9.7043 18.6324 0.0 0
M  V30 42 A -8.467 18.0501 0.0 0
M  V30 43 N -11.4511 24.8432 0.0 0
M  V30 44 C -10.2138 24.916 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 2 5 9
M  V30 9 2 5 10
M  V30 10 2 7 11
M  V30 11 1 7 12
M  V30 12 1 13 14
M  V30 13 1 13 15
M  V30 14 1 13 16
M  V30 15 1 14 17
M  V30 16 1 15 18
M  V30 17 1 16 19
M  V30 18 1 17 20
M  V30 19 2 17 21
M  V30 20 2 17 22
M  V30 21 2 19 23
M  V30 22 1 19 24
M  V30 23 1 24 25
M  V30 24 1 26 27
M  V30 25 1 27 28
M  V30 26 2 29 30
M  V30 27 1 30 31
M  V30 28 1 30 32
M  V30 29 1 31 33
M  V30 30 2 34 35
M  V30 31 1 35 36
M  V30 32 1 35 37
M  V30 33 1 36 38
M  V30 34 1 39 40
M  V30 35 1 41 42
M  V30 36 1 43 44
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00063001.cdx

>  <name>
US20220000799A1-20220106-C00039

>  <Row No>
863

$$$$
US20220000799A1-20220106-C00040
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Y 0.0 0.0 0.0 0 VAL=3
M  V30 2 O -0.0602 1.2859 0.0 0
M  V30 3 C -1.2859 0.0602 0.0 0
M  V30 4 C 1.1854 0.0602 0.0 0
M  V30 5 S -0.1205 2.5919 0.0 0
M  V30 6 N -3.697 0.1004 0.0 0
M  V30 7 C 3.6368 0.1205 0.0 0
M  V30 8 F -0.1808 3.8779 0.0 0
M  V30 9 O -1.4065 2.6522 0.0 0
M  V30 10 O 1.0649 2.6522 0.0 0
M  V30 11 O 3.5765 1.4065 0.0 0
M  V30 12 N 4.8222 0.1808 0.0 0
M  V30 13 Y 8.1979 -7.3941 0.0 0 VAL=3
M  V30 14 O 8.1376 -6.0278 0.0 0
M  V30 15 C 6.8315 -7.3339 0.0 0
M  V30 16 C 9.4637 -7.3339 0.0 0
M  V30 17 S 8.0773 -4.6615 0.0 0
M  V30 18 N 4.2596 -7.2937 0.0 0
M  V30 19 C 11.7342 -7.2736 0.0 0
M  V30 20 O 6.711 -4.6012 0.0 0
M  V30 21 O 9.3231 -4.6012 0.0 0
M  V30 22 O 8.017 -3.2952 0.0 0 CHG=-1
M  V30 23 O 11.6739 -5.9073 0.0 0
M  V30 24 N 13.0001 -7.2133 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 2 5 9
M  V30 9 2 5 10
M  V30 10 2 7 11
M  V30 11 1 7 12
M  V30 12 1 13 14
M  V30 13 1 13 15
M  V30 14 1 13 16
M  V30 15 1 14 17
M  V30 16 1 15 18
M  V30 17 1 16 19
M  V30 18 2 17 20
M  V30 19 2 17 21
M  V30 20 1 17 22
M  V30 21 2 19 23
M  V30 22 1 19 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00064001.cdx

>  <name>
US20220000799A1-20220106-C00040

>  <Row No>
864

$$$$
US20220000799A1-20220106-C00041
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 224 236 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -1.0794 -1.7647 0.0 0
M  V30 3 O 2.0388 0.0514 0.0 0
M  V30 4 O -1.0794 1.8675 0.0 0
M  V30 5 S 17.2706 16.174 0.0 0
M  V30 6 F 15.4716 14.6834 0.0 0
M  V30 7 O 18.7612 14.4778 0.0 0
M  V30 8 O 15.6772 17.9731 0.0 0
M  V30 9 O 18.9668 17.7674 0.0 0
M  V30 10 C 18.5385 19.6693 0.0 0
M  V30 11 C 16.688 20.3032 0.0 0
M  V30 12 C 19.9091 20.9886 0.0 0
M  V30 13 C 16.2597 22.205 0.0 0
M  V30 14 C 19.4808 22.8904 0.0 0
M  V30 15 C 17.6304 23.5243 0.0 0
M  V30 16 C 17.202 25.4261 0.0 0
M  V30 17 C 15.3516 26.0601 0.0 0 CFG=2
M  V30 18 N 14.4435 24.4324 0.0 0
M  V30 19 C 15.6086 27.979 0.0 0
M  V30 20 C 13.0386 23.1474 0.0 0
M  V30 21 O 17.4419 28.0133 0.0 0
M  V30 22 N 15.2831 29.898 0.0 0
M  V30 23 O 14.0666 21.6568 0.0 0
M  V30 24 C 11.291 22.3592 0.0 0 CFG=1
M  V30 25 C 14.3921 31.6456 0.0 0 CFG=2
M  V30 26 N 11.805 20.6116 0.0 0
M  V30 27 C 9.372 22.1365 0.0 0
M  V30 28 C 13.0043 33.0506 0.0 0
M  V30 29 C 15.8828 32.8107 0.0 0 CFG=2
M  V30 30 S 7.453 22.4963 0.0 0
M  V30 31 O 14.0495 34.6269 0.0 0
M  V30 32 C 11.291 33.9587 0.0 0
M  V30 33 C 17.5618 32.0911 0.0 0
M  V30 34 C 15.6429 34.7468 0.0 0
M  V30 35 S 5.7226 23.4044 0.0 0
M  V30 36 C 9.372 34.3013 0.0 0 CFG=2
M  V30 37 C 19.0525 33.2562 0.0 0
M  V30 38 C 4.3347 24.8093 0.0 0
M  V30 39 C 7.453 34.0786 0.0 0
M  V30 40 C 9.3206 36.2374 0.0 0
M  V30 41 C 3.4438 26.557 0.0 0 CFG=2
M  V30 42 O 6.8362 35.929 0.0 0
M  V30 43 N 5.7054 33.2905 0.0 0
M  V30 44 C 7.6244 37.214 0.0 0
M  V30 45 N 3.1011 28.4759 0.0 0
M  V30 46 C 1.5934 26.043 0.0 0
M  V30 47 C 4.3005 32.0054 0.0 0 CFG=2
M  V30 48 C 7.573 39.1501 0.0 0
M  V30 49 C 3.3581 30.3949 0.0 0
M  V30 50 O 0.137 27.3794 0.0 0
M  V30 51 N 1.1479 24.2439 0.0 0
M  V30 52 C 2.7242 33.1877 0.0 0
M  V30 53 O 9.1664 40.1267 0.0 0
M  V30 54 N 5.8768 40.1267 0.0 0
M  V30 55 O 1.5077 31.0288 0.0 0
M  V30 56 C -0.6339 23.5415 0.0 0 CFG=2
M  V30 57 C 2.3644 22.8732 0.0 0
M  V30 58 C 2.8784 35.1237 0.0 0
M  V30 59 C -2.3301 24.5352 0.0 0
M  V30 60 C -0.4968 21.7082 0.0 0
M  V30 61 C 1.3706 21.2798 0.0 0
M  V30 62 O 4.5575 35.9119 0.0 0
M  V30 63 N 1.3021 36.306 0.0 0
M  V30 64 O -2.3815 26.4713 0.0 0
M  V30 65 N -4.0263 23.6614 0.0 0
M  V30 66 C -5.7226 24.6551 0.0 0 CFG=2
M  V30 67 C -5.774 26.5912 0.0 0
M  V30 68 C -7.4188 23.7813 0.0 0
M  V30 69 O -7.4702 27.585 0.0 0
M  V30 70 N -4.1805 27.5678 0.0 0
M  V30 71 C -7.4702 21.948 0.0 0
M  V30 72 C -4.2319 29.5039 0.0 0
M  V30 73 C -9.1664 21.0742 0.0 0
M  V30 74 C -5.8768 21.0571 0.0 0
M  V30 75 C -2.6385 30.4805 0.0 0
M  V30 76 O -1.0451 29.6067 0.0 0
M  V30 77 N -2.6899 32.4166 0.0 0
M  V30 78 C -4.3861 33.3933 0.0 0 CFG=2
M  V30 79 C -4.4375 35.3293 0.0 0
M  V30 80 C -6.0824 32.5194 0.0 0
M  V30 81 O -2.8441 36.306 0.0 0
M  V30 82 N -6.1338 36.306 0.0 0
M  V30 83 C -7.7786 33.4961 0.0 0
M  V30 84 C -6.1852 38.2421 0.0 0
M  V30 85 C -9.4748 34.4727 0.0 0
M  V30 86 C -4.5917 39.2187 0.0 0
M  V30 87 O -2.9983 38.3449 0.0 0
M  V30 88 O -4.6431 41.1548 0.0 0
M  V30 89 F -5.7568 2.8784 0.0 0
M  V30 90 C -4.7459 2.313 0.0 0
M  V30 91 C -4.7973 1.1136 0.0 0
M  V30 92 C -3.7351 2.9812 0.0 0
M  V30 93 C -3.7865 0.5482 0.0 0
M  V30 94 C -2.7242 2.4158 0.0 0
M  V30 95 C -2.7756 1.2164 0.0 0
M  V30 96 C -1.7647 0.651 0.0 0
M  V30 97 C -0.5996 1.0108 0.0 0 CFG=2
M  V30 98 N 0.2056 0.2056 0.0 0
M  V30 99 C -0.3426 2.2787 0.0 0
M  V30 100 C -0.1542 -0.9594 0.0 0
M  V30 101 O -1.2507 3.1868 0.0 0
M  V30 102 N 0.8224 2.6385 0.0 0
M  V30 103 O -1.422 -1.2164 0.0 0
M  V30 104 C 0.651 -1.7647 0.0 0 CFG=1
M  V30 105 C 1.0794 3.9064 0.0 0 CFG=2
M  V30 106 N 1.8332 -1.5248 0.0 0
M  V30 107 C 0.4112 -2.9469 0.0 0
M  V30 108 C 2.2444 4.2662 0.0 0
M  V30 109 C 0.1713 4.8145 0.0 0
M  V30 110 C 2.3301 -0.3598 0.0 0
M  V30 111 C 2.3301 -2.5529 0.0 0
M  V30 112 C 1.4392 -3.4438 0.0 0
M  V30 113 O 2.5014 5.5341 0.0 0
M  V30 114 N 3.0497 3.4609 0.0 0
M  V30 115 C 0.4283 6.0824 0.0 0
M  V30 116 O 1.6105 0.7196 0.0 0
M  V30 117 C 3.8721 -0.2398 0.0 0 CFG=1
M  V30 118 C 4.2319 3.7008 0.0 0 CFG=2
M  V30 119 C 2.8099 2.2787 0.0 0
M  V30 120 C 1.542 6.5621 0.0 0
M  V30 121 C -0.394 7.0761 0.0 0
M  V30 122 N 4.4889 -1.2164 0.0 0
M  V30 123 C 4.369 0.908 0.0 0
M  V30 124 C 4.7288 4.8659 0.0 0
M  V30 125 C 4.7288 2.6728 0.0 0
M  V30 126 C 3.8379 1.7818 0.0 0
M  V30 127 C 1.422 7.8643 0.0 0
M  V30 128 C 2.57 6.0652 0.0 0
M  V30 129 N 0.2227 8.1555 0.0 0
M  V30 130 C 3.8893 -2.2444 0.0 0
M  V30 131 C 5.5684 1.028 0.0 0
M  V30 132 O 4.0092 5.9453 0.0 0
M  V30 133 N 5.9282 4.9858 0.0 0
M  V30 134 C 2.3986 8.5839 0.0 0
M  V30 135 C 3.5466 6.7848 0.0 0
M  V30 136 O 2.5871 -2.2616 0.0 0
M  V30 137 C 4.5061 -3.2211 0.0 0 CFG=1
M  V30 138 C 6.1852 2.1074 0.0 0
M  V30 139 C 6.288 0.137 0.0 0
M  V30 140 C 6.425 6.1509 0.0 0 CFG=2
M  V30 141 C 3.4267 8.087 0.0 0
M  V30 142 N 3.9064 -4.2491 0.0 0
M  V30 143 C 5.7054 -3.1011 0.0 0
M  V30 144 C 7.3502 1.8504 0.0 0
M  V30 145 C 5.8254 3.3753 0.0 0
M  V30 146 N 7.4016 0.6168 0.0 0
M  V30 147 C 7.6244 6.2708 0.0 0
M  V30 148 C 5.7054 7.2303 0.0 0
M  V30 149 C 2.6043 -4.2662 0.0 0
M  V30 150 C 6.3222 -4.0777 0.0 0
M  V30 151 C 8.1555 2.7585 0.0 0
M  V30 152 C 6.6306 4.2833 0.0 0
M  V30 153 O 8.2412 5.2942 0.0 0
M  V30 154 N 8.1213 7.4359 0.0 0
M  V30 155 C 6.2023 8.3954 0.0 0
M  V30 156 O 1.8846 -3.2039 0.0 0
M  V30 157 C 2.0217 -5.3456 0.0 0 CFG=1
M  V30 158 C 7.5216 -3.9578 0.0 0
M  V30 159 C 7.7957 4.0263 0.0 0
M  V30 160 C 9.3206 7.5558 0.0 0 CFG=2
M  V30 161 N 7.3331 8.858 0.0 0
M  V30 162 C 5.4142 9.4063 0.0 0
M  V30 163 N 0.7196 -5.3799 0.0 0
M  V30 164 C 2.6557 -6.3051 0.0 0
M  V30 165 C 8.1384 -4.9344 0.0 0
M  V30 166 C 9.8003 8.7381 0.0 0
M  V30 167 C 9.9374 6.5964 0.0 0
M  V30 168 C 7.2474 10.1601 0.0 0
M  V30 169 C 6.0481 10.4686 0.0 0
M  V30 170 C 0.137 -6.425 0.0 0
M  V30 171 C 3.855 -6.168 0.0 0
M  V30 172 N 9.3377 -4.8145 0.0 0
M  V30 173 O 9.0636 9.8003 0.0 0
M  V30 174 N 10.9997 8.8751 0.0 0
M  V30 175 C 9.3377 5.5512 0.0 0
M  V30 176 C 8.087 11.0511 0.0 0
M  V30 177 C 5.7054 11.7364 0.0 0
M  V30 178 O 0.771 -7.3845 0.0 0
M  V30 179 C -1.165 -6.4593 0.0 0 CFG=1
M  V30 180 C 4.5917 -7.059 0.0 0
M  V30 181 C 4.4547 -5.0886 0.0 0
M  V30 182 C 11.4794 10.0573 0.0 0 CFG=2
M  V30 183 C 9.9545 4.5917 0.0 0
M  V30 184 C 7.7443 12.319 0.0 0
M  V30 185 C 6.545 12.6274 0.0 0
M  V30 186 N -1.8675 -7.4359 0.0 0
M  V30 187 C -2.0046 -5.4656 0.0 0
M  V30 188 C 5.7054 -6.5621 0.0 0
M  V30 189 C 4.369 -8.2412 0.0 0
M  V30 190 N 5.6198 -5.3285 0.0 0
M  V30 191 C 10.7427 11.1196 0.0 0
M  V30 192 C 12.6788 10.1944 0.0 0
M  V30 193 N 9.3549 3.5466 0.0 0
M  V30 194 C -1.4734 -8.5496 0.0 0
M  V30 195 C -3.1354 -7.0932 0.0 0
M  V30 196 C -3.2211 -5.8596 0.0 0
M  V30 197 C 6.6135 -7.2646 0.0 0
M  V30 198 C 5.2771 -8.9437 0.0 0
M  V30 199 O 11.2224 12.3018 0.0 0
M  V30 200 N 9.4405 11.0854 0.0 0
M  V30 201 C 13.1585 11.3766 0.0 0
M  V30 202 C 9.9717 2.5871 0.0 0
M  V30 203 O -0.2912 -8.6695 0.0 0
M  V30 204 C -2.6557 -9.8346 0.0 0 CFG=1
M  V30 205 C 6.3908 -8.4468 0.0 0
M  V30 206 C 14.3579 11.5137 0.0 0
M  V30 207 N 9.372 1.542 0.0 0
M  V30 208 N 11.171 2.7071 0.0 0
M  V30 209 N -3.9407 -9.6119 0.0 0
M  V30 210 C -2.2616 -10.9483 0.0 0
M  V30 211 N 14.8376 12.6959 0.0 0
M  V30 212 C -4.4375 -8.3954 0.0 0
M  V30 213 C -3.0669 -11.8564 0.0 0
M  V30 214 C 16.037 12.833 0.0 0
M  V30 215 O -3.7351 -7.3845 0.0 0
M  V30 216 C -5.7226 -8.1727 0.0 0 CFG=1
M  V30 217 C -3.8721 -12.7645 0.0 0
M  V30 218 N 16.6709 11.8735 0.0 0
M  V30 219 N 16.4996 14.0152 0.0 0
M  V30 220 N -6.5278 -9.0807 0.0 0
M  V30 221 C -6.2194 -6.9562 0.0 0 CFG=2
M  V30 222 C -7.5044 -6.7334 0.0 0
M  V30 223 C -5.517 -5.9453 0.0 0
M  V30 224 C -8.0013 -5.517 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 5 6
M  V30 5 2 5 7
M  V30 6 2 5 8
M  V30 7 1 5 9
M  V30 8 1 9 10
M  V30 9 2 10 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 2 12 14
M  V30 13 2 13 15
M  V30 14 1 15 16
M  V30 15 1 17 16 CFG=3
M  V30 16 1 17 18
M  V30 17 1 17 19
M  V30 18 1 18 20
M  V30 19 2 19 21
M  V30 20 1 19 22
M  V30 21 2 20 23
M  V30 22 1 20 24
M  V30 23 1 25 22 CFG=3
M  V30 24 1 24 26 CFG=1
M  V30 25 1 24 27
M  V30 26 1 25 28
M  V30 27 1 25 29
M  V30 28 1 27 30
M  V30 29 2 28 31
M  V30 30 1 28 32
M  V30 31 1 29 33
M  V30 32 1 29 34 CFG=1
M  V30 33 1 30 35
M  V30 34 1 32 36
M  V30 35 1 33 37
M  V30 36 1 35 38
M  V30 37 1 36 39
M  V30 38 1 36 40 CFG=3
M  V30 39 1 38 41
M  V30 40 2 39 42
M  V30 41 1 39 43
M  V30 42 1 40 44
M  V30 43 1 41 45
M  V30 44 1 41 46 CFG=1
M  V30 45 1 43 47
M  V30 46 1 44 48
M  V30 47 1 45 49
M  V30 48 2 46 50
M  V30 49 1 46 51
M  V30 50 1 47 52 CFG=3
M  V30 51 2 48 53
M  V30 52 1 48 54
M  V30 53 2 49 55
M  V30 54 1 51 56
M  V30 55 1 51 57
M  V30 56 1 52 58
M  V30 57 1 56 59 CFG=1
M  V30 58 1 56 60
M  V30 59 1 57 61
M  V30 60 2 58 62
M  V30 61 1 58 63
M  V30 62 2 59 64
M  V30 63 1 59 65
M  V30 64 1 66 65 CFG=1
M  V30 65 1 66 67
M  V30 66 1 66 68
M  V30 67 2 67 69
M  V30 68 1 67 70
M  V30 69 1 68 71
M  V30 70 1 70 72
M  V30 71 1 71 73
M  V30 72 1 71 74
M  V30 73 1 72 75
M  V30 74 2 75 76
M  V30 75 1 75 77
M  V30 76 1 78 77 CFG=1
M  V30 77 1 78 79
M  V30 78 1 78 80
M  V30 79 2 79 81
M  V30 80 1 79 82
M  V30 81 1 80 83
M  V30 82 1 82 84
M  V30 83 3 83 85
M  V30 84 1 84 86
M  V30 85 2 86 87
M  V30 86 1 86 88
M  V30 87 1 89 90
M  V30 88 2 90 91
M  V30 89 1 90 92
M  V30 90 1 91 93
M  V30 91 2 92 94
M  V30 92 2 93 95
M  V30 93 1 95 96
M  V30 94 1 96 97
M  V30 95 1 97 98 CFG=1
M  V30 96 1 97 99
M  V30 97 1 98 100
M  V30 98 2 99 101
M  V30 99 1 99 102
M  V30 100 2 100 103
M  V30 101 1 104 100 CFG=1
M  V30 102 1 105 102 CFG=1
M  V30 103 1 104 106
M  V30 104 1 104 107
M  V30 105 1 105 108
M  V30 106 1 105 109
M  V30 107 1 106 110
M  V30 108 1 106 111
M  V30 109 1 107 112
M  V30 110 2 108 113
M  V30 111 1 108 114
M  V30 112 1 109 115
M  V30 113 2 110 116
M  V30 114 1 110 117
M  V30 115 1 114 118
M  V30 116 1 114 119
M  V30 117 1 115 120
M  V30 118 2 115 121
M  V30 119 1 117 122 CFG=3
M  V30 120 1 117 123
M  V30 121 1 118 124 CFG=3
M  V30 122 1 118 125
M  V30 123 1 119 126
M  V30 124 2 120 127
M  V30 125 1 120 128
M  V30 126 1 121 129
M  V30 127 1 122 130
M  V30 128 1 123 131
M  V30 129 2 124 132
M  V30 130 1 124 133
M  V30 131 1 127 134
M  V30 132 2 128 135
M  V30 133 2 130 136
M  V30 134 1 130 137
M  V30 135 1 131 138
M  V30 136 2 131 139
M  V30 137 1 140 133 CFG=1
M  V30 138 2 134 141
M  V30 139 1 137 142 CFG=3
M  V30 140 1 137 143
M  V30 141 2 138 144
M  V30 142 1 138 145
M  V30 143 1 139 146
M  V30 144 1 140 147
M  V30 145 1 140 148
M  V30 146 1 142 149
M  V30 147 1 143 150
M  V30 148 1 144 151
M  V30 149 2 145 152
M  V30 150 2 147 153
M  V30 151 1 147 154
M  V30 152 1 148 155
M  V30 153 2 149 156
M  V30 154 1 149 157
M  V30 155 1 150 158
M  V30 156 2 151 159
M  V30 157 1 160 154 CFG=3
M  V30 158 1 155 161
M  V30 159 2 155 162
M  V30 160 1 157 163 CFG=3
M  V30 161 1 157 164
M  V30 162 1 158 165
M  V30 163 1 160 166
M  V30 164 1 160 167
M  V30 165 1 161 168
M  V30 166 1 162 169
M  V30 167 1 163 170
M  V30 168 1 164 171
M  V30 169 1 165 172
M  V30 170 2 166 173
M  V30 171 1 166 174
M  V30 172 1 167 175
M  V30 173 1 168 176
M  V30 174 1 169 177
M  V30 175 2 170 178
M  V30 176 1 179 170 CFG=1
M  V30 177 1 171 180
M  V30 178 2 171 181
M  V30 179 1 182 174 CFG=3
M  V30 180 1 175 183
M  V30 181 2 176 184
M  V30 182 2 177 185
M  V30 183 1 179 186
M  V30 184 1 179 187
M  V30 185 2 180 188
M  V30 186 1 180 189
M  V30 187 1 181 190
M  V30 188 1 182 191
M  V30 189 1 182 192
M  V30 190 1 183 193
M  V30 191 1 186 194
M  V30 192 1 186 195
M  V30 193 1 187 196
M  V30 194 1 188 197
M  V30 195 2 189 198
M  V30 196 2 191 199
M  V30 197 1 191 200
M  V30 198 1 192 201
M  V30 199 1 193 202
M  V30 200 2 194 203
M  V30 201 1 194 204
M  V30 202 2 197 205
M  V30 203 1 201 206
M  V30 204 2 202 207
M  V30 205 1 202 208
M  V30 206 1 204 209 CFG=3
M  V30 207 1 204 210
M  V30 208 1 206 211
M  V30 209 1 209 212
M  V30 210 1 210 213
M  V30 211 1 211 214
M  V30 212 2 212 215
M  V30 213 1 212 216
M  V30 214 3 213 217
M  V30 215 2 214 218
M  V30 216 1 214 219
M  V30 217 1 216 220 CFG=1
M  V30 218 1 216 221
M  V30 219 1 221 222
M  V30 220 1 221 223 CFG=3
M  V30 221 1 222 224
M  V30 222 1 14 15
M  V30 223 1 47 49
M  V30 224 1 60 61
M  V30 225 1 94 95
M  V30 226 1 111 112
M  V30 227 1 125 126
M  V30 228 1 127 129
M  V30 229 1 135 141
M  V30 230 1 144 146
M  V30 231 1 152 159
M  V30 232 2 168 169
M  V30 233 1 184 185
M  V30 234 1 188 190
M  V30 235 1 195 196
M  V30 236 1 198 205
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(24 17 24 25 29 36 41 47 56 66 78 97 104 105 117 118 137 140 157 160 179 182 204 216 221)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00066001.cdx

>  <name>
US20220000799A1-20220106-C00041

>  <Row No>
865

$$$$
US20220000799A1-20220106-C00042
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 157 159 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.6581 -1.2065 0.0 0
M  V30 3 O 0.6581 1.4259 0.0 0
M  V30 4 O -1.6087 0.1096 0.0 0
M  V30 5 S 1.1699 -36.8548 0.0 0
M  V30 6 F 0.1828 -37.9517 0.0 0
M  V30 7 O 2.2668 -37.6226 0.0 0
M  V30 8 O -0.1462 -35.8676 0.0 0
M  V30 9 O 1.9378 -35.5386 0.0 0
M  V30 10 C 1.2065 -34.0395 0.0 0
M  V30 11 C -0.4021 -33.7836 0.0 0
M  V30 12 C 1.9743 -32.7233 0.0 0
M  V30 13 C -1.1334 -32.2845 0.0 0
M  V30 14 C 1.2431 -31.2242 0.0 0
M  V30 15 C -0.3656 -30.9683 0.0 0
M  V30 16 C -1.0968 -29.4692 0.0 0
M  V30 17 C -0.329 -28.153 0.0 0 CFG=2
M  V30 18 N 0.914 -28.738 0.0 0
M  V30 19 C -1.499 -26.983 0.0 0
M  V30 20 C 2.3034 -28.8842 0.0 0
M  V30 21 O -2.8153 -27.7508 0.0 0
M  V30 22 N -2.3034 -25.5205 0.0 0
M  V30 23 O 2.1937 -30.2736 0.0 0
M  V30 24 C 3.6927 -28.5551 0.0 0 CFG=1
M  V30 25 C -2.6324 -23.9117 0.0 0 CFG=2
M  V30 26 N 4.0584 -29.8714 0.0 0
M  V30 27 C 4.9359 -27.7508 0.0 0
M  V30 28 C -2.5228 -22.303 0.0 0
M  V30 29 C -4.2412 -23.802 0.0 0
M  V30 30 S 5.8865 -26.5808 0.0 0
M  V30 31 O -4.0584 -21.718 0.0 0
M  V30 32 N -1.9378 -20.8405 0.0 0
M  V30 33 C -5.1187 -25.0086 0.0 0
M  V30 34 S 6.4715 -25.1183 0.0 0
M  V30 35 C -0.9871 -19.6705 0.0 0 CFG=2
M  V30 36 C -4.4606 -26.2152 0.0 0
M  V30 37 C -6.7274 -24.8989 0.0 0
M  V30 38 C 6.6177 -23.5095 0.0 0
M  V30 39 C 0.2559 -18.8661 0.0 0
M  V30 40 C -1.9743 -18.3543 0.0 0
M  V30 41 C -5.3381 -27.4217 0.0 0
M  V30 42 C -7.6049 -26.1055 0.0 0
M  V30 43 C 6.2887 -21.9008 0.0 0 CFG=2
M  V30 44 O -0.329 -17.3305 0.0 0
M  V30 45 C 1.6453 -18.5005 0.0 0
M  V30 46 C -1.4624 -16.8552 0.0 0
M  V30 47 C -6.9468 -27.312 0.0 0
M  V30 48 N 5.4843 -20.4383 0.0 0
M  V30 49 C 7.6049 -21.3158 0.0 0
M  V30 50 C 2.9981 -18.6468 0.0 0 CFG=2
M  V30 51 C -2.4496 -15.539 0.0 0
M  V30 52 C 4.3143 -19.2683 0.0 0
M  V30 53 O 7.8243 -19.7436 0.0 0
M  V30 54 N 8.6287 -22.2299 0.0 0
M  V30 55 C 3.3637 -17.1111 0.0 0
M  V30 56 O -1.9378 -14.0399 0.0 0
M  V30 57 N -4.0584 -15.5755 0.0 0
M  V30 58 O 5.0821 -17.9521 0.0 0
M  V30 59 C 9.9815 -21.7911 0.0 0 CFG=2
M  V30 60 C 8.3727 -23.6192 0.0 0
M  V30 61 C 2.2668 -15.868 0.0 0
M  V30 62 C 10.4933 -20.2921 0.0 0
M  V30 63 C 10.6396 -22.9977 0.0 0
M  V30 64 C 9.6524 -24.1311 0.0 0
M  V30 65 O 2.6324 -14.3324 0.0 0
M  V30 66 N 0.6946 -16.0508 0.0 0
M  V30 67 O 9.5062 -18.9758 0.0 0
M  V30 68 N 11.8827 -20.0361 0.0 0
M  V30 69 C 12.3946 -18.5371 0.0 0 CFG=2
M  V30 70 C 13.784 -18.2811 0.0 0
M  V30 71 C 11.4074 -17.2208 0.0 0
M  V30 72 O 14.2958 -16.7821 0.0 0
M  V30 73 N 14.5518 -19.378 0.0 0
M  V30 74 C 9.7987 -17.2574 0.0 0
M  V30 75 C 15.9411 -19.1221 0.0 0
M  V30 76 C 8.8115 -15.9411 0.0 0
M  V30 77 C 16.7455 -20.2189 0.0 0
M  V30 78 N 7.2027 -15.9777 0.0 0
M  V30 79 O 18.1349 -19.9264 0.0 0
M  V30 80 N 16.0508 -21.4986 0.0 0
M  V30 81 C 6.2156 -14.6615 0.0 0
M  V30 82 C 16.7089 -22.7052 0.0 0 CFG=2
M  V30 83 N 6.7274 -13.1624 0.0 0
M  V30 84 N 4.6068 -14.698 0.0 0
M  V30 85 C 15.8314 -23.9117 0.0 0
M  V30 86 C 18.0983 -22.5955 0.0 0
M  V30 87 O 14.2227 -23.802 0.0 0
M  V30 88 N 16.4896 -25.1183 0.0 0
M  V30 89 C 19.0489 -23.5461 0.0 0
M  V30 90 C 15.6121 -26.3248 0.0 0
M  V30 91 C 19.9996 -24.4967 0.0 0
M  V30 92 C 16.2702 -27.5314 0.0 0
M  V30 93 O 17.6596 -27.4217 0.0 0
M  V30 94 O 15.3927 -28.738 0.0 0
M  V30 95 F -4.3874 -1.4624 0.0 0
M  V30 96 C -3.1809 -0.5849 0.0 0
M  V30 97 C -1.9743 -1.2431 0.0 0
M  V30 98 C -3.2906 1.0237 0.0 0
M  V30 99 C -0.7678 -0.3656 0.0 0
M  V30 100 C -2.084 1.9012 0.0 0
M  V30 101 C -0.8774 1.2431 0.0 0
M  V30 102 C 0.329 2.1206 0.0 0
M  V30 103 C 1.5356 1.4624 0.0 0 CFG=1
M  V30 104 C 1.4259 0.0731 0.0 0
M  V30 105 C 2.7421 2.3399 0.0 0
M  V30 106 O 0.0 -0.5849 0.0 0
M  V30 107 N 2.6324 -0.5849 0.0 0
M  V30 108 C 3.9487 1.6818 0.0 0
M  V30 109 C 2.5228 -1.9743 0.0 0
M  V30 110 O 3.839 0.2924 0.0 0
M  V30 111 C 5.1552 2.5593 0.0 0 CFG=1
M  V30 112 C 3.7293 -2.6324 0.0 0
M  V30 113 N 6.3618 1.9012 0.0 0
M  V30 114 C 5.0456 4.1681 0.0 0
M  V30 115 O 4.9359 -1.7549 0.0 0
M  V30 116 N 3.6196 -4.0218 0.0 0
M  V30 117 C 7.5684 2.7787 0.0 0
M  V30 118 C 3.6196 5.0456 0.0 0
M  V30 119 C 6.2521 5.0456 0.0 0
M  V30 120 C 4.8262 -4.6799 0.0 0 CFG=2
M  V30 121 O 7.4587 4.3874 0.0 0
M  V30 122 C 8.7749 2.1206 0.0 0 CFG=2
M  V30 123 C 4.7165 -6.0693 0.0 0
M  V30 124 C 6.0327 -3.8024 0.0 0
M  V30 125 C 8.6652 0.7312 0.0 0
M  V30 126 C 9.9815 2.9981 0.0 0
M  V30 127 O 3.2906 -6.7274 0.0 0
M  V30 128 N 5.9231 -6.7274 0.0 0
M  V30 129 C 7.2393 -4.4606 0.0 0
M  V30 130 C 7.2393 0.0731 0.0 0
M  V30 131 C 11.188 2.3399 0.0 0
M  V30 132 C 5.8134 -8.1168 0.0 0
M  V30 133 C 8.4459 -5.1187 0.0 0
M  V30 134 O 5.8134 0.9506 0.0 0
M  V30 135 O 7.1296 -1.3162 0.0 0
M  V30 136 O 11.0783 0.9506 0.0 0
M  V30 137 C 12.3946 3.2174 0.0 0 CFG=1
M  V30 138 C 7.0199 -8.7749 0.0 0
M  V30 139 N 13.6011 2.5593 0.0 0
M  V30 140 C 12.2849 4.8262 0.0 0
M  V30 141 O 8.2265 -7.8974 0.0 0
M  V30 142 O 6.9102 -10.1643 0.0 0
M  V30 143 C 14.8077 3.4368 0.0 0
M  V30 144 C 13.4915 5.7037 0.0 0
M  V30 145 O 14.698 5.0456 0.0 0
M  V30 146 C 16.0143 2.7787 0.0 0 CFG=1
M  V30 147 C 13.3818 7.3124 0.0 0
M  V30 148 N 15.9046 1.3893 0.0 0
M  V30 149 C 17.2208 3.6562 0.0 0
M  V30 150 C 14.5883 8.1899 0.0 0
M  V30 151 C 18.4274 2.9981 0.0 0
M  V30 152 N 14.4786 9.7987 0.0 0
M  V30 153 C 19.6339 3.8756 0.0 0
M  V30 154 N 20.8405 3.2174 0.0 0
M  V30 155 C 22.047 4.0949 0.0 0
M  V30 156 N 23.2536 3.4368 0.0 0
M  V30 157 N 21.9374 5.7037 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 5 6
M  V30 5 2 5 7
M  V30 6 2 5 8
M  V30 7 1 5 9
M  V30 8 1 9 10
M  V30 9 2 10 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 2 12 14
M  V30 13 2 13 15
M  V30 14 1 15 16
M  V30 15 1 17 16 CFG=1
M  V30 16 1 17 18
M  V30 17 1 17 19
M  V30 18 1 18 20
M  V30 19 2 19 21
M  V30 20 1 19 22
M  V30 21 2 20 23
M  V30 22 1 20 24
M  V30 23 1 22 25
M  V30 24 1 24 26 CFG=3
M  V30 25 1 24 27
M  V30 26 1 25 28
M  V30 27 1 25 29 CFG=1
M  V30 28 1 27 30
M  V30 29 2 28 31
M  V30 30 1 28 32
M  V30 31 1 29 33
M  V30 32 1 30 34
M  V30 33 1 32 35
M  V30 34 2 33 36
M  V30 35 1 33 37
M  V30 36 1 34 38
M  V30 37 1 35 39
M  V30 38 1 35 40 CFG=1
M  V30 39 1 36 41
M  V30 40 2 37 42
M  V30 41 1 38 43
M  V30 42 2 39 44
M  V30 43 1 39 45
M  V30 44 1 40 46
M  V30 45 2 41 47
M  V30 46 1 43 48
M  V30 47 1 43 49 CFG=3
M  V30 48 1 45 50
M  V30 49 1 46 51
M  V30 50 1 48 52
M  V30 51 2 49 53
M  V30 52 1 49 54
M  V30 53 1 50 55 CFG=1
M  V30 54 2 51 56
M  V30 55 1 51 57
M  V30 56 2 52 58
M  V30 57 1 54 59
M  V30 58 1 54 60
M  V30 59 1 55 61
M  V30 60 1 59 62 CFG=3
M  V30 61 1 59 63
M  V30 62 1 60 64
M  V30 63 2 61 65
M  V30 64 1 61 66
M  V30 65 2 62 67
M  V30 66 1 62 68
M  V30 67 1 69 68 CFG=1
M  V30 68 1 69 70
M  V30 69 1 69 71
M  V30 70 2 70 72
M  V30 71 1 70 73
M  V30 72 1 71 74
M  V30 73 1 73 75
M  V30 74 1 74 76
M  V30 75 1 75 77
M  V30 76 1 76 78
M  V30 77 2 77 79
M  V30 78 1 77 80
M  V30 79 1 78 81
M  V30 80 1 82 80 CFG=1
M  V30 81 2 81 83
M  V30 82 1 81 84
M  V30 83 1 82 85
M  V30 84 1 82 86
M  V30 85 2 85 87
M  V30 86 1 85 88
M  V30 87 1 86 89
M  V30 88 1 88 90
M  V30 89 3 89 91
M  V30 90 1 90 92
M  V30 91 2 92 93
M  V30 92 1 92 94
M  V30 93 1 95 96
M  V30 94 2 96 97
M  V30 95 1 96 98
M  V30 96 1 97 99
M  V30 97 2 98 100
M  V30 98 2 99 101
M  V30 99 1 101 102
M  V30 100 1 103 102 CFG=3
M  V30 101 1 103 104
M  V30 102 1 103 105
M  V30 103 2 104 106
M  V30 104 1 104 107
M  V30 105 1 105 108
M  V30 106 1 107 109
M  V30 107 2 108 110
M  V30 108 1 108 111
M  V30 109 1 109 112
M  V30 110 1 111 113 CFG=3
M  V30 111 1 111 114
M  V30 112 2 112 115
M  V30 113 1 112 116
M  V30 114 1 113 117
M  V30 115 1 114 118
M  V30 116 1 114 119
M  V30 117 1 120 116 CFG=1
M  V30 118 2 117 121
M  V30 119 1 117 122
M  V30 120 1 120 123
M  V30 121 1 120 124
M  V30 122 1 122 125 CFG=1
M  V30 123 1 122 126
M  V30 124 2 123 127
M  V30 125 1 123 128
M  V30 126 1 124 129
M  V30 127 1 125 130
M  V30 128 1 126 131
M  V30 129 1 128 132
M  V30 130 3 129 133
M  V30 131 2 130 134
M  V30 132 1 130 135
M  V30 133 2 131 136
M  V30 134 1 131 137
M  V30 135 1 132 138
M  V30 136 1 137 139 CFG=3
M  V30 137 1 137 140
M  V30 138 2 138 141
M  V30 139 1 138 142
M  V30 140 1 139 143
M  V30 141 1 140 144
M  V30 142 2 143 145
M  V30 143 1 143 146
M  V30 144 1 144 147
M  V30 145 1 146 148 CFG=3
M  V30 146 1 146 149
M  V30 147 1 147 150
M  V30 148 1 149 151
M  V30 149 1 150 152
M  V30 150 1 151 153
M  V30 151 1 153 154
M  V30 152 1 154 155
M  V30 153 2 155 156
M  V30 154 1 155 157
M  V30 155 1 14 15
M  V30 156 1 42 47
M  V30 157 1 50 52
M  V30 158 1 63 64
M  V30 159 1 100 101
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(15 17 24 25 35 43 50 59 69 82 103 111 120 122 137 146)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00067001.cdx

>  <name>
US20220000799A1-20220106-C00042

>  <Row No>
866

$$$$
US20220000799A1-20220106-C00043
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 108 114 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.2181 0.8411 0.0 0
M  V30 3 C 2.4363 0.174 0.0 0
M  V30 4 C 1.1311 2.4363 0.0 0
M  V30 5 O 2.3493 -1.2471 0.0 0
M  V30 6 C 3.6545 1.0151 0.0 0
M  V30 7 C 2.3493 3.2775 0.0 0
M  V30 8 Cl 4.8727 0.348 0.0 0
M  V30 9 C 3.5675 2.6104 0.0 0
M  V30 10 N 2.2623 4.8727 0.0 0
M  V30 11 N 3.4805 5.7139 0.0 0
M  V30 12 C 3.3935 7.3091 0.0 0
M  V30 13 C 4.6117 8.1502 0.0 0
M  V30 14 C 2.0013 8.1502 0.0 0
M  V30 15 C 4.5247 9.7455 0.0 0
M  V30 16 C 1.9143 9.7455 0.0 0
M  V30 17 O 5.7429 10.5866 0.0 0
M  V30 18 C 3.1324 10.5866 0.0 0
M  V30 19 S 6.9611 9.9195 0.0 0
M  V30 20 F 8.1792 9.2524 0.0 0
M  V30 21 O 7.6282 11.3117 0.0 0
M  V30 22 O 6.1199 8.7013 0.0 0
M  V30 23 Cl 8.5853 0.6961 0.0 0
M  V30 24 C 9.8035 1.5372 0.0 0
M  V30 25 C 11.0217 0.8701 0.0 0
M  V30 26 C 9.7165 3.1324 0.0 0
M  V30 27 O 10.9347 -0.551 0.0 0
M  V30 28 C 12.2399 1.7112 0.0 0
M  V30 29 C 10.9347 3.9736 0.0 0
M  V30 30 Cl 13.4581 1.0441 0.0 0
M  V30 31 C 12.1529 3.3065 0.0 0
M  V30 32 N 10.8477 5.5688 0.0 0
M  V30 33 N 12.0659 6.41 0.0 0
M  V30 34 C 11.9788 8.0052 0.0 0
M  V30 35 C 10.5866 8.8464 0.0 0
M  V30 36 C 13.197 8.8464 0.0 0
M  V30 37 C 10.4996 10.4416 0.0 0
M  V30 38 C 13.11 10.4416 0.0 0
M  V30 39 C 11.7178 11.2827 0.0 0
M  V30 40 O 11.6308 12.878 0.0 0
M  V30 41 S 12.849 13.7191 0.0 0
M  V30 42 F 14.0672 14.5603 0.0 0
M  V30 43 O 12.0079 15.1113 0.0 0
M  V30 44 O 13.5161 12.5009 0.0 0
M  V30 45 Cl 10.6736 20.8833 0.0 0
M  V30 46 C 11.8918 21.7244 0.0 0
M  V30 47 C 13.11 21.0573 0.0 0
M  V30 48 C 11.8048 23.3196 0.0 0
M  V30 49 C 14.3282 21.8984 0.0 0
M  V30 50 C 13.023 24.1608 0.0 0
M  V30 51 Cl 15.5464 21.2313 0.0 0
M  V30 52 C 14.2412 23.4937 0.0 0
M  V30 53 C 12.936 25.756 0.0 0
M  V30 54 O 14.0672 26.7422 0.0 0
M  V30 55 N 11.6308 26.7422 0.0 0
M  V30 56 C 13.5161 28.2504 0.0 0
M  V30 57 C 12.0079 28.2504 0.0 0
M  V30 58 C 14.1832 29.6426 0.0 0
M  V30 59 C 11.1667 29.6426 0.0 0
M  V30 60 C 13.3421 31.0349 0.0 0
M  V30 61 C 11.8338 31.0349 0.0 0
M  V30 62 C 14.0092 32.4271 0.0 0
M  V30 63 O 13.168 33.8193 0.0 0
M  V30 64 O 15.4304 32.5141 0.0 0
M  V30 65 S 23.2036 9.7455 0.0 0
M  V30 66 F 24.4218 9.0784 0.0 0
M  V30 67 O 23.8707 11.1377 0.0 0
M  V30 68 O 22.3625 8.5273 0.0 0
M  V30 69 O 21.8114 10.5866 0.0 0
M  V30 70 C 20.4192 9.9195 0.0 0
M  V30 71 C 20.3322 8.4983 0.0 0
M  V30 72 C 19.027 10.7607 0.0 0
M  V30 73 C 18.9399 7.8312 0.0 0
M  V30 74 C 17.6347 10.0935 0.0 0
M  V30 75 N 18.8529 6.41 0.0 0
M  V30 76 C 17.5477 8.6723 0.0 0
M  V30 77 N 17.4607 5.7429 0.0 0
M  V30 78 C 17.3737 4.3216 0.0 0
M  V30 79 C 15.9815 3.6545 0.0 0
M  V30 80 C 18.5919 3.6545 0.0 0
M  V30 81 C 15.8945 2.2333 0.0 0
M  V30 82 C 18.5049 2.2333 0.0 0
M  V30 83 C 17.1127 1.5662 0.0 0
M  V30 84 C 14.5022 1.5662 0.0 0
M  V30 85 C 19.7231 1.5662 0.0 0
M  V30 86 O 17.0256 0.145 0.0 0
M  V30 87 S 29.2366 12.762 0.0 0
M  V30 88 F 30.4548 13.6031 0.0 0
M  V30 89 O 28.3954 14.1542 0.0 0
M  V30 90 O 29.9037 11.5438 0.0 0
M  V30 91 O 27.8444 12.0949 0.0 0
M  V30 92 C 27.7573 10.6736 0.0 0
M  V30 93 C 26.3651 10.0065 0.0 0
M  V30 94 C 28.9755 10.0065 0.0 0
M  V30 95 C 26.2781 8.5853 0.0 0
M  V30 96 C 28.8885 8.5853 0.0 0
M  V30 97 C 27.4963 7.9182 0.0 0
M  V30 98 N 27.4093 6.497 0.0 0
M  V30 99 N 26.0171 5.8299 0.0 0
M  V30 100 C 25.9301 4.4086 0.0 0
M  V30 101 C 24.5378 3.7415 0.0 0
M  V30 102 C 27.1482 3.7415 0.0 0
M  V30 103 C 24.4508 2.3203 0.0 0
M  V30 104 C 27.0612 2.3203 0.0 0
M  V30 105 C 25.669 1.6532 0.0 0
M  V30 106 C 23.0586 1.6532 0.0 0
M  V30 107 C 28.2794 1.6532 0.0 0
M  V30 108 O 25.582 0.232 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 6 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 10 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 1 15 17
M  V30 17 2 15 18
M  V30 18 1 17 19
M  V30 19 1 19 20
M  V30 20 2 19 21
M  V30 21 2 19 22
M  V30 22 1 23 24
M  V30 23 2 24 25
M  V30 24 1 24 26
M  V30 25 1 25 27
M  V30 26 1 25 28
M  V30 27 2 26 29
M  V30 28 1 28 30
M  V30 29 2 28 31
M  V30 30 1 29 32
M  V30 31 2 32 33
M  V30 32 1 33 34
M  V30 33 2 34 35
M  V30 34 1 34 36
M  V30 35 1 35 37
M  V30 36 2 36 38
M  V30 37 2 37 39
M  V30 38 1 39 40
M  V30 39 1 40 41
M  V30 40 1 41 42
M  V30 41 2 41 43
M  V30 42 2 41 44
M  V30 43 1 45 46
M  V30 44 2 46 47
M  V30 45 1 46 48
M  V30 46 1 47 49
M  V30 47 2 48 50
M  V30 48 1 49 51
M  V30 49 2 49 52
M  V30 50 1 50 53
M  V30 51 1 53 54
M  V30 52 2 53 55
M  V30 53 1 54 56
M  V30 54 1 55 57
M  V30 55 1 56 58
M  V30 56 1 57 59
M  V30 57 2 58 60
M  V30 58 2 59 61
M  V30 59 1 60 62
M  V30 60 2 62 63
M  V30 61 1 62 64
M  V30 62 1 65 66
M  V30 63 2 65 67
M  V30 64 2 65 68
M  V30 65 1 65 69
M  V30 66 1 69 70
M  V30 67 2 70 71
M  V30 68 1 70 72
M  V30 69 1 71 73
M  V30 70 2 72 74
M  V30 71 1 73 75
M  V30 72 2 73 76
M  V30 73 2 75 77
M  V30 74 1 77 78
M  V30 75 2 78 79
M  V30 76 1 78 80
M  V30 77 1 79 81
M  V30 78 2 80 82
M  V30 79 2 81 83
M  V30 80 1 81 84
M  V30 81 1 82 85
M  V30 82 1 83 86
M  V30 83 1 87 88
M  V30 84 2 87 89
M  V30 85 2 87 90
M  V30 86 1 87 91
M  V30 87 1 91 92
M  V30 88 2 92 93
M  V30 89 1 92 94
M  V30 90 1 93 95
M  V30 91 2 94 96
M  V30 92 2 95 97
M  V30 93 1 97 98
M  V30 94 2 98 99
M  V30 95 1 99 100
M  V30 96 2 100 101
M  V30 97 1 100 102
M  V30 98 1 101 103
M  V30 99 2 102 104
M  V30 100 2 103 105
M  V30 101 1 103 106
M  V30 102 1 104 107
M  V30 103 1 105 108
M  V30 104 1 7 9
M  V30 105 1 16 18
M  V30 106 1 29 31
M  V30 107 1 38 39
M  V30 108 1 50 52
M  V30 109 2 56 57
M  V30 110 1 60 61
M  V30 111 1 74 76
M  V30 112 1 82 83
M  V30 113 1 96 97
M  V30 114 1 104 105
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00068001.cdx

>  <name>
US20220000799A1-20220106-C00043

>  <Row No>
867

$$$$
US20220000799A1-20220106-C00044
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 50 54 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.5829 1.3919 0.0 0
M  V30 3 C 2.0225 1.5823 0.0 0
M  V30 4 C -0.3212 2.6293 0.0 0
M  V30 5 O 2.8553 0.4164 0.0 0
M  V30 6 C 2.6055 2.9743 0.0 0
M  V30 7 C 0.2617 4.0212 0.0 0
M  V30 8 Cl 4.045 3.1646 0.0 0
M  V30 9 C 1.7013 4.2116 0.0 0
M  V30 10 C -0.6424 5.2586 0.0 0
M  V30 11 O -0.2141 6.71 0.0 0
M  V30 12 N -2.1653 5.2943 0.0 0
M  V30 13 C -1.4514 7.6142 0.0 0
M  V30 14 N -2.665 6.7457 0.0 0
M  V30 15 C -1.4871 9.1371 0.0 0
M  V30 16 C -0.2379 9.9104 0.0 0
M  V30 17 C -2.8077 9.9104 0.0 0
M  V30 18 C -0.2736 11.4333 0.0 0
M  V30 19 C -2.8434 11.4333 0.0 0
M  V30 20 O 0.9755 12.1947 0.0 0
M  V30 21 C -1.5942 12.1947 0.0 0
M  V30 22 S 2.2248 11.4809 0.0 0
M  V30 23 F 3.474 10.767 0.0 0
M  V30 24 O 2.9386 12.8015 0.0 0
M  V30 25 O 1.4514 10.2317 0.0 0
M  V30 26 Cl 7.8046 0.2855 0.0 0
M  V30 27 C 8.3876 1.6775 0.0 0
M  V30 28 C 9.8271 1.8678 0.0 0
M  V30 29 C 7.4834 2.9148 0.0 0
M  V30 30 O 10.66 0.7019 0.0 0
M  V30 31 C 10.4101 3.2598 0.0 0
M  V30 32 C 8.0663 4.3068 0.0 0
M  V30 33 Cl 11.8497 3.4502 0.0 0
M  V30 34 C 9.5059 4.4971 0.0 0
M  V30 35 C 7.1621 5.5441 0.0 0
M  V30 36 O 7.5904 6.9956 0.0 0
M  V30 37 N 5.6393 5.5798 0.0 0
M  V30 38 C 6.3531 7.8998 0.0 0
M  V30 39 N 5.1396 7.0313 0.0 0
M  V30 40 C 6.3174 9.4226 0.0 0
M  V30 41 C 4.9968 10.1841 0.0 0
M  V30 42 C 7.5667 10.1841 0.0 0
M  V30 43 C 4.9611 11.7069 0.0 0
M  V30 44 C 7.531 11.7069 0.0 0
M  V30 45 C 6.2104 12.4802 0.0 0
M  V30 46 O 6.1747 14.0031 0.0 0
M  V30 47 S 4.8541 14.7764 0.0 0
M  V30 48 F 3.5335 15.5498 0.0 0
M  V30 49 O 5.5679 16.097 0.0 0
M  V30 50 O 4.0807 13.5272 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 6 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 1 10 11
M  V30 11 2 10 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 1 20 22
M  V30 22 1 22 23
M  V30 23 2 22 24
M  V30 24 2 22 25
M  V30 25 1 26 27
M  V30 26 2 27 28
M  V30 27 1 27 29
M  V30 28 1 28 30
M  V30 29 1 28 31
M  V30 30 2 29 32
M  V30 31 1 31 33
M  V30 32 2 31 34
M  V30 33 1 32 35
M  V30 34 1 35 36
M  V30 35 2 35 37
M  V30 36 1 36 38
M  V30 37 1 37 39
M  V30 38 1 38 40
M  V30 39 2 40 41
M  V30 40 1 40 42
M  V30 41 1 41 43
M  V30 42 2 42 44
M  V30 43 2 43 45
M  V30 44 1 45 46
M  V30 45 1 46 47
M  V30 46 1 47 48
M  V30 47 2 47 49
M  V30 48 2 47 50
M  V30 49 1 7 9
M  V30 50 2 13 14
M  V30 51 1 19 21
M  V30 52 1 32 34
M  V30 53 2 38 39
M  V30 54 1 44 45
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00069001.cdx

>  <name>
US20220000799A1-20220106-C00044

>  <Row No>
868

$$$$
US20220000799A1-20220106-C00045
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 145 154 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.5505 -0.6645 0.0 0
M  V30 3 C -1.6835 -2.1265 0.0 0
M  V30 4 C -3.1011 0.2658 0.0 0
M  V30 5 C -3.234 -2.791 0.0 0
M  V30 6 C -0.3987 -2.791 0.0 0
M  V30 7 C -4.6517 -0.3987 0.0 0
M  V30 8 C -4.7846 -1.8607 0.0 0
M  V30 9 C 0.886 -1.8607 0.0 0
M  V30 10 C -6.3352 -2.5252 0.0 0 CFG=1
M  V30 11 C 2.1708 -2.5252 0.0 0
M  V30 12 C 0.7531 -0.1329 0.0 0
M  V30 13 O -7.8858 -1.5948 0.0 0
M  V30 14 C -6.4681 -3.9872 0.0 0 CFG=1
M  V30 15 C 3.4556 -1.5948 0.0 0
M  V30 16 C 2.0379 0.7974 0.0 0
M  V30 17 C -9.4364 -2.2594 0.0 0 CFG=2
M  V30 18 O -5.1834 -4.6517 0.0 0
M  V30 19 C -8.0187 -4.6517 0.0 0 CFG=1
M  V30 20 C 3.3227 0.1329 0.0 0
M  V30 21 C -9.5693 -3.7214 0.0 0 CFG=1
M  V30 22 C -10.987 -1.329 0.0 0
M  V30 23 O -8.1517 -6.1137 0.0 0
M  V30 24 O 4.6074 1.0632 0.0 0
M  V30 25 O -11.1199 -4.3859 0.0 0
M  V30 26 O -12.5376 -1.9936 0.0 0
M  V30 27 S 5.8922 0.3987 0.0 0
M  V30 28 F 7.177 -0.2658 0.0 0
M  V30 29 O 6.5568 1.9493 0.0 0
M  V30 30 O 4.9619 -0.886 0.0 0
M  V30 31 Cl -0.7088 34.7333 0.0 0
M  V30 32 C -2.2594 34.0687 0.0 0
M  V30 33 C -2.3923 32.6068 0.0 0
M  V30 34 C -3.81 34.9991 0.0 0
M  V30 35 C -3.9429 31.9422 0.0 0
M  V30 36 C -1.1075 31.9422 0.0 0
M  V30 37 C -5.3606 34.3346 0.0 0
M  V30 38 C -5.4935 32.8726 0.0 0
M  V30 39 C 0.1772 32.8726 0.0 0
M  V30 40 C -7.0441 32.208 0.0 0 CFG=1
M  V30 41 C 1.4619 32.208 0.0 0
M  V30 42 C 0.0443 34.6004 0.0 0
M  V30 43 O -8.5947 33.1384 0.0 0
M  V30 44 C -7.177 30.746 0.0 0 CFG=1
M  V30 45 C 2.7467 33.1384 0.0 0
M  V30 46 C 1.329 35.5307 0.0 0
M  V30 47 C -10.1453 32.4738 0.0 0 CFG=2
M  V30 48 O -5.8922 30.0815 0.0 0
M  V30 49 C -8.7276 30.0815 0.0 0 CFG=1
M  V30 50 C 2.6138 34.8662 0.0 0
M  V30 51 C -10.2782 31.0119 0.0 0 CFG=1
M  V30 52 C -11.6959 33.4042 0.0 0
M  V30 53 O -8.8605 28.6195 0.0 0
M  V30 54 O 3.8986 35.7966 0.0 0
M  V30 55 O -11.8288 30.3473 0.0 0
M  V30 56 O -13.2465 32.7397 0.0 0
M  V30 57 C 3.7657 37.5244 0.0 0
M  V30 58 F 3.6328 39.2522 0.0 0
M  V30 59 F 2.2151 38.4547 0.0 0
M  V30 60 F 5.0505 38.4547 0.0 0
M  V30 61 Cl -6.0251 45.3659 0.0 0
M  V30 62 C -7.2213 44.8786 0.0 0
M  V30 63 C -7.3542 43.8153 0.0 0
M  V30 64 C -8.4175 45.6318 0.0 0
M  V30 65 C -8.5504 43.328 0.0 0
M  V30 66 C -6.4238 43.328 0.0 0
M  V30 67 C -9.6136 45.1444 0.0 0
M  V30 68 C -9.7465 44.0812 0.0 0
M  V30 69 C -5.4935 44.0812 0.0 0
M  V30 70 C -10.9427 43.5938 0.0 0 CFG=1
M  V30 71 C -4.5631 43.5938 0.0 0
M  V30 72 C -5.6264 45.4102 0.0 0
M  V30 73 O -12.1389 44.347 0.0 0
M  V30 74 C -11.0756 42.5306 0.0 0 CFG=1
M  V30 75 C -3.6328 44.347 0.0 0
M  V30 76 C -4.696 46.1634 0.0 0
M  V30 77 C -13.3351 43.8596 0.0 0 CFG=2
M  V30 78 O -10.1453 42.0432 0.0 0
M  V30 79 C -12.2718 42.0432 0.0 0 CFG=1
M  V30 80 C -3.7657 45.6761 0.0 0
M  V30 81 C -13.468 42.7964 0.0 0 CFG=1
M  V30 82 C -14.5312 44.6128 0.0 0
M  V30 83 O -12.4047 40.98 0.0 0
M  V30 84 O -2.8353 46.4292 0.0 0
M  V30 85 O -14.6642 42.3091 0.0 0
M  V30 86 O -15.7274 44.1255 0.0 0
M  V30 87 C -2.9682 48.157 0.0 0
M  V30 88 C -1.6835 49.0874 0.0 0
M  V30 89 Cl -5.3163 10.2782 0.0 0
M  V30 90 C -6.6011 9.7465 0.0 0
M  V30 91 C -6.734 8.5504 0.0 0
M  V30 92 C -7.8858 10.544 0.0 0
M  V30 93 C -8.0187 8.0187 0.0 0
M  V30 94 C -5.715 8.0187 0.0 0
M  V30 95 C -9.1706 10.0124 0.0 0
M  V30 96 C -9.3035 8.8162 0.0 0
M  V30 97 C -4.696 8.8162 0.0 0
M  V30 98 C -10.5883 8.2846 0.0 0 CFG=1
M  V30 99 C -3.6771 8.2846 0.0 0
M  V30 100 C -4.8289 10.2782 0.0 0
M  V30 101 O -11.8731 9.082 0.0 0
M  V30 102 C -10.7212 7.0884 0.0 0 CFG=1
M  V30 103 C -2.6581 9.082 0.0 0
M  V30 104 C -3.81 11.0756 0.0 0
M  V30 105 C -13.1579 8.5504 0.0 0 CFG=2
M  V30 106 O -9.7022 6.5568 0.0 0
M  V30 107 C -12.006 6.5568 0.0 0 CFG=1
M  V30 108 C -2.791 10.544 0.0 0
M  V30 109 C -13.2908 7.3542 0.0 0 CFG=1
M  V30 110 C -14.4426 9.3478 0.0 0
M  V30 111 O -12.1389 5.3606 0.0 0
M  V30 112 O -1.7721 11.3414 0.0 0
M  V30 113 O -14.5755 6.8226 0.0 0
M  V30 114 O -15.7274 8.8162 0.0 0
M  V30 115 Cl -2.8353 22.6829 0.0 0
M  V30 116 C -4.3859 22.0184 0.0 0
M  V30 117 C -4.5188 20.5564 0.0 0
M  V30 118 C -5.9365 22.9488 0.0 0
M  V30 119 C -6.0694 19.8919 0.0 0
M  V30 120 C -3.234 19.8919 0.0 0
M  V30 121 C -7.4871 22.2842 0.0 0
M  V30 122 C -7.62 20.8222 0.0 0
M  V30 123 C -1.9493 20.8222 0.0 0
M  V30 124 C -9.1706 20.1577 0.0 0 CFG=1
M  V30 125 C -0.6645 20.1577 0.0 0
M  V30 126 C -2.0822 22.55 0.0 0
M  V30 127 O -10.7212 21.088 0.0 0
M  V30 128 C -9.3035 18.6957 0.0 0 CFG=1
M  V30 129 C 0.6202 21.088 0.0 0
M  V30 130 C -0.7974 23.4804 0.0 0
M  V30 131 C -12.2718 20.4235 0.0 0 CFG=2
M  V30 132 O -8.0187 18.0312 0.0 0
M  V30 133 C -10.8541 18.0312 0.0 0 CFG=1
M  V30 134 C 0.4873 22.8159 0.0 0
M  V30 135 C -12.4047 18.9615 0.0 0 CFG=1
M  V30 136 C -13.8224 21.3539 0.0 0
M  V30 137 O -10.987 16.5692 0.0 0
M  V30 138 C 1.7721 23.7462 0.0 0
M  V30 139 O -13.9553 18.297 0.0 0
M  V30 140 O -15.373 20.6893 0.0 0
M  V30 141 S 0.7088 9.5693 0.0 0
M  V30 142 F 2.1708 9.7022 0.0 0
M  V30 143 F -1.0189 9.7022 0.0 0
M  V30 144 O 0.5759 11.2971 0.0 0
M  V30 145 O 0.5759 8.1073 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 1 10 8 CFG=3
M  V30 10 2 9 11
M  V30 11 1 9 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 2 12 16
M  V30 16 1 13 17
M  V30 17 1 14 18 CFG=1
M  V30 18 1 14 19
M  V30 19 2 15 20
M  V30 20 1 17 21
M  V30 21 1 17 22 CFG=3
M  V30 22 1 19 23 CFG=3
M  V30 23 1 20 24
M  V30 24 1 21 25 CFG=1
M  V30 25 1 22 26
M  V30 26 1 24 27
M  V30 27 1 27 28
M  V30 28 2 27 29
M  V30 29 2 27 30
M  V30 30 1 31 32
M  V30 31 2 32 33
M  V30 32 1 32 34
M  V30 33 1 33 35
M  V30 34 1 33 36
M  V30 35 2 34 37
M  V30 36 2 35 38
M  V30 37 1 36 39
M  V30 38 1 40 38 CFG=3
M  V30 39 2 39 41
M  V30 40 1 39 42
M  V30 41 1 40 43
M  V30 42 1 40 44
M  V30 43 1 41 45
M  V30 44 2 42 46
M  V30 45 1 43 47
M  V30 46 1 44 48 CFG=1
M  V30 47 1 44 49
M  V30 48 2 45 50
M  V30 49 1 47 51
M  V30 50 1 47 52 CFG=3
M  V30 51 1 49 53 CFG=3
M  V30 52 1 50 54
M  V30 53 1 51 55 CFG=1
M  V30 54 1 52 56
M  V30 55 1 54 57
M  V30 56 1 57 58
M  V30 57 1 57 59
M  V30 58 1 57 60
M  V30 59 1 61 62
M  V30 60 2 62 63
M  V30 61 1 62 64
M  V30 62 1 63 65
M  V30 63 1 63 66
M  V30 64 2 64 67
M  V30 65 2 65 68
M  V30 66 1 66 69
M  V30 67 1 70 68 CFG=3
M  V30 68 2 69 71
M  V30 69 1 69 72
M  V30 70 1 70 73
M  V30 71 1 70 74
M  V30 72 1 71 75
M  V30 73 2 72 76
M  V30 74 1 73 77
M  V30 75 1 74 78 CFG=1
M  V30 76 1 74 79
M  V30 77 2 75 80
M  V30 78 1 77 81
M  V30 79 1 77 82 CFG=3
M  V30 80 1 79 83 CFG=3
M  V30 81 1 80 84
M  V30 82 1 81 85 CFG=1
M  V30 83 1 82 86
M  V30 84 1 84 87
M  V30 85 1 87 88
M  V30 86 1 89 90
M  V30 87 2 90 91
M  V30 88 1 90 92
M  V30 89 1 91 93
M  V30 90 1 91 94
M  V30 91 2 92 95
M  V30 92 2 93 96
M  V30 93 1 94 97
M  V30 94 1 98 96 CFG=3
M  V30 95 2 97 99
M  V30 96 1 97 100
M  V30 97 1 98 101
M  V30 98 1 98 102
M  V30 99 1 99 103
M  V30 100 2 100 104
M  V30 101 1 101 105
M  V30 102 1 102 106 CFG=1
M  V30 103 1 102 107
M  V30 104 2 103 108
M  V30 105 1 105 109
M  V30 106 1 105 110 CFG=3
M  V30 107 1 107 111 CFG=3
M  V30 108 1 108 112
M  V30 109 1 109 113 CFG=1
M  V30 110 1 110 114
M  V30 111 1 115 116
M  V30 112 2 116 117
M  V30 113 1 116 118
M  V30 114 1 117 119
M  V30 115 1 117 120
M  V30 116 2 118 121
M  V30 117 2 119 122
M  V30 118 1 120 123
M  V30 119 1 124 122 CFG=3
M  V30 120 2 123 125
M  V30 121 1 123 126
M  V30 122 1 124 127
M  V30 123 1 124 128
M  V30 124 1 125 129
M  V30 125 2 126 130
M  V30 126 1 127 131
M  V30 127 1 128 132 CFG=1
M  V30 128 1 128 133
M  V30 129 2 129 134
M  V30 130 1 131 135
M  V30 131 1 131 136 CFG=3
M  V30 132 1 133 137 CFG=3
M  V30 133 1 134 138
M  V30 134 1 135 139 CFG=1
M  V30 135 1 136 140
M  V30 136 1 141 142
M  V30 137 1 141 143
M  V30 138 2 141 144
M  V30 139 2 141 145
M  V30 140 1 7 8
M  V30 141 1 16 20
M  V30 142 1 19 21
M  V30 143 1 37 38
M  V30 144 1 46 50
M  V30 145 1 49 51
M  V30 146 1 67 68
M  V30 147 1 76 80
M  V30 148 1 79 81
M  V30 149 1 95 96
M  V30 150 1 104 108
M  V30 151 1 107 109
M  V30 152 1 121 122
M  V30 153 1 130 134
M  V30 154 1 133 135
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(25 10 14 17 19 21 40 44 47 49 51 70 74 77 79 81 98 102 105 107 109 124 128 131 133 135)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00070001.cdx

>  <name>
US20220000799A1-20220106-C00045

>  <Row No>
869

$$$$
US20220000799A1-20220106-C00046
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 94 103 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O 0.7006 -1.2308 0.0 0
M  V30 3 O 0.7006 1.3444 0.0 0
M  V30 4 O -1.5527 0.0568 0.0 0
M  V30 5 S -0.4544 13.9372 0.0 0
M  V30 6 O 0.2461 12.7064 0.0 0
M  V30 7 O 0.2461 15.2817 0.0 0
M  V30 8 O -2.0072 13.9941 0.0 0
M  V30 9 F -4.0902 11.3619 0.0 0
M  V30 10 C -2.8594 12.1762 0.0 0
M  V30 11 C -1.6285 11.4755 0.0 0
M  V30 12 C -2.9162 13.7289 0.0 0
M  V30 13 C -0.3976 12.2898 0.0 0
M  V30 14 C -1.6853 14.5432 0.0 0
M  V30 15 C -0.4544 13.8426 0.0 0
M  V30 16 C 0.8332 11.5891 0.0 0
M  V30 17 C 0.7763 14.6568 0.0 0
M  V30 18 C 2.064 12.4034 0.0 0
M  V30 19 C 2.0072 13.9562 0.0 0
M  V30 20 C 0.7195 16.2096 0.0 0
M  V30 21 C 3.2381 14.7705 0.0 0
M  V30 22 C 1.9504 17.0239 0.0 0
M  V30 23 C 3.1813 16.3233 0.0 0 CFG=2
M  V30 24 C 4.6015 14.3539 0.0 0
M  V30 25 C 4.5447 16.8535 0.0 0
M  V30 26 C 3.276 17.8571 0.0 0
M  V30 27 C 5.4537 15.6037 0.0 0
M  V30 28 O 4.9613 18.3305 0.0 0
M  V30 29 C 5.965 17.1565 0.0 0
M  V30 30 C 7.4041 17.2133 0.0 0
M  V30 31 F -4.0902 -2.1208 0.0 0
M  V30 32 C -2.8594 -1.3066 0.0 0
M  V30 33 C -1.6285 -2.0072 0.0 0
M  V30 34 C -2.9162 0.2461 0.0 0
M  V30 35 C -0.3976 -1.193 0.0 0
M  V30 36 C -1.6853 1.0604 0.0 0
M  V30 37 C -0.4544 0.3597 0.0 0
M  V30 38 C 0.8332 -1.8936 0.0 0
M  V30 39 C 0.7763 1.174 0.0 0
M  V30 40 C 2.064 -1.0793 0.0 0
M  V30 41 C 2.0072 0.4734 0.0 0
M  V30 42 C 0.7195 2.7268 0.0 0
M  V30 43 C 3.2381 1.2876 0.0 0
M  V30 44 C 1.9504 3.5411 0.0 0
M  V30 45 C 3.1813 2.8404 0.0 0 CFG=2
M  V30 46 C 4.6015 0.871 0.0 0
M  V30 47 C 4.5447 3.3707 0.0 0
M  V30 48 C 3.276 4.3743 0.0 0
M  V30 49 C 5.4537 2.1208 0.0 0
M  V30 50 O 4.9613 4.8477 0.0 0
M  V30 51 C 5.965 3.6736 0.0 0
M  V30 52 N 6.9307 4.8666 0.0 0
M  V30 53 C 6.6656 2.4428 0.0 0
M  V30 54 N 8.2373 4.2985 0.0 0
M  V30 55 N 8.0669 2.8215 0.0 0
M  V30 56 C 9.1463 1.8557 0.0 0
M  V30 57 C 10.5097 2.386 0.0 0
M  V30 58 O 11.5891 1.4202 0.0 0
M  V30 59 C 12.9525 1.9504 0.0 0
M  V30 60 C 14.0319 0.9847 0.0 0
M  V30 61 O 15.3954 1.5149 0.0 0
M  V30 62 C 16.4747 0.5491 0.0 0
M  V30 63 C 17.8382 1.0793 0.0 0
M  V30 64 O 18.9176 0.1136 0.0 0
M  V30 65 C 20.281 0.6438 0.0 0
M  V30 66 C 21.3604 -0.3219 0.0 0
M  V30 67 C 22.7238 0.2083 0.0 0
M  V30 68 C 24.1062 0.6627 0.0 0
M  V30 69 O 25.4885 0.3219 0.0 0
M  V30 70 C 24.0494 2.2155 0.0 0
M  V30 71 C 22.7049 3.0298 0.0 0
M  V30 72 C 25.2802 3.0298 0.0 0
M  V30 73 C 22.6481 4.5826 0.0 0
M  V30 74 C 25.2234 4.5826 0.0 0
M  V30 75 C 23.8789 5.3969 0.0 0
M  V30 76 C 21.3036 5.3969 0.0 0
M  V30 77 C 23.8221 7.8207 0.0 0
M  V30 78 O 21.6444 6.8929 0.0 0
M  V30 79 O 19.9591 4.6962 0.0 0
M  V30 80 C 22.4776 8.635 0.0 0
M  V30 81 C 25.053 8.635 0.0 0
M  V30 82 C 22.4208 10.1878 0.0 0
M  V30 83 C 21.1331 7.9344 0.0 0
M  V30 84 C 24.9962 10.1878 0.0 0
M  V30 85 C 26.2839 7.9344 0.0 0
M  V30 86 O 23.6517 11.0021 0.0 0
M  V30 87 C 21.0763 11.0021 0.0 0
M  V30 88 C 19.7886 8.7486 0.0 0
M  V30 89 C 26.2271 11.0021 0.0 0
M  V30 90 C 27.5148 8.7486 0.0 0
M  V30 91 C 19.7318 10.3014 0.0 0
M  V30 92 C 27.4579 10.3014 0.0 0
M  V30 93 O 18.3873 11.1157 0.0 0
M  V30 94 O 28.6888 11.1157 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 2 5 6
M  V30 5 2 5 7
M  V30 6 2 5 8
M  V30 7 1 9 10
M  V30 8 2 10 11
M  V30 9 1 10 12
M  V30 10 1 11 13
M  V30 11 2 12 14
M  V30 12 2 13 15
M  V30 13 1 13 16
M  V30 14 1 15 17
M  V30 15 1 16 18
M  V30 16 1 17 19
M  V30 17 1 17 20
M  V30 18 1 19 21
M  V30 19 1 20 22
M  V30 20 1 21 23
M  V30 21 1 21 24
M  V30 22 1 23 25
M  V30 23 1 23 26 CFG=1
M  V30 24 1 24 27
M  V30 25 1 25 28
M  V30 26 1 25 29
M  V30 27 3 29 30
M  V30 28 1 31 32
M  V30 29 2 32 33
M  V30 30 1 32 34
M  V30 31 1 33 35
M  V30 32 2 34 36
M  V30 33 2 35 37
M  V30 34 1 35 38
M  V30 35 1 37 39
M  V30 36 1 38 40
M  V30 37 1 39 41
M  V30 38 1 39 42
M  V30 39 1 41 43
M  V30 40 1 42 44
M  V30 41 1 43 45
M  V30 42 1 43 46
M  V30 43 1 45 47
M  V30 44 1 45 48 CFG=1
M  V30 45 1 46 49
M  V30 46 1 47 50
M  V30 47 1 47 51
M  V30 48 1 51 52
M  V30 49 2 51 53
M  V30 50 2 52 54
M  V30 51 1 53 55
M  V30 52 1 55 56
M  V30 53 1 56 57
M  V30 54 1 57 58
M  V30 55 1 58 59
M  V30 56 1 59 60
M  V30 57 1 60 61
M  V30 58 1 61 62
M  V30 59 1 62 63
M  V30 60 1 63 64
M  V30 61 1 64 65
M  V30 62 1 65 66
M  V30 63 1 66 67
M  V30 64 1 67 68
M  V30 65 2 68 69
M  V30 66 1 68 70
M  V30 67 2 70 71
M  V30 68 1 70 72
M  V30 69 1 71 73
M  V30 70 2 72 74
M  V30 71 2 73 75
M  V30 72 1 73 76
M  V30 73 1 75 77
M  V30 74 2 76 78
M  V30 75 1 76 79
M  V30 76 2 77 80
M  V30 77 1 77 81
M  V30 78 1 80 82
M  V30 79 1 80 83
M  V30 80 2 81 84
M  V30 81 1 81 85
M  V30 82 1 82 86
M  V30 83 2 82 87
M  V30 84 2 83 88
M  V30 85 1 84 89
M  V30 86 2 85 90
M  V30 87 1 87 91
M  V30 88 2 89 92
M  V30 89 2 91 93
M  V30 90 1 92 94
M  V30 91 1 14 15
M  V30 92 1 18 19
M  V30 93 1 22 23
M  V30 94 1 25 27
M  V30 95 1 36 37
M  V30 96 1 40 41
M  V30 97 1 44 45
M  V30 98 1 47 49
M  V30 99 1 54 55
M  V30 100 1 74 75
M  V30 101 1 84 86
M  V30 102 1 88 91
M  V30 103 1 90 92
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 23 45)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00071001.cdx

>  <name>
US20220000799A1-20220106-C00046

>  <Row No>
870

$$$$
US20220000799A1-20220106-C00047
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 49 49 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.8102 -1.2443 0.0 0
M  V30 3 O 1.4468 0.0434 0.0 0
M  V30 4 O -0.8102 1.3311 0.0 0
M  V30 5 S -5.556 6.3663 0.0 0
M  V30 6 F -4.1091 6.4097 0.0 0
M  V30 7 F -7.0898 6.4097 0.0 0
M  V30 8 O -5.5995 7.9 0.0 0
M  V30 9 O -5.5995 4.9194 0.0 0
M  V30 10 S 1.0417 1.852 0.0 0
M  V30 11 C 1.8954 0.6945 0.0 0
M  V30 12 C -0.4196 1.4179 0.0 0
M  V30 13 N 0.9549 -0.463 0.0 0
M  V30 14 N 3.3423 0.7379 0.0 0
M  V30 15 C -0.463 -0.0289 0.0 0
M  V30 16 C -1.7507 2.2282 0.0 0
M  V30 17 C -1.7941 -0.7523 0.0 0
M  V30 18 C -3.0818 1.5047 0.0 0
M  V30 19 C -3.1253 0.0578 0.0 0
M  V30 20 F -4.413 2.315 0.0 0
M  V30 21 S -9.6074 6.9451 0.0 0
M  V30 22 C -8.7537 5.7875 0.0 0
M  V30 23 C -11.0687 6.5255 0.0 0
M  V30 24 N -9.6942 4.63 0.0 0
M  V30 25 N -7.3068 5.831 0.0 0
M  V30 26 C -11.1121 5.0786 0.0 0
M  V30 27 C -12.3999 7.3357 0.0 0
M  V30 28 C -12.4433 4.3551 0.0 0
M  V30 29 C -13.731 6.6123 0.0 0
M  V30 30 C -13.7744 5.1654 0.0 0
M  V30 31 O -15.0622 7.4225 0.0 0
M  V30 32 S -4.0513 14.8162 0.0 0
M  V30 33 C -3.1976 13.6587 0.0 0
M  V30 34 C -5.5126 14.3966 0.0 0
M  V30 35 N -4.1381 12.5012 0.0 0
M  V30 36 N -1.7507 13.7021 0.0 0
M  V30 37 C -5.556 12.9497 0.0 0
M  V30 38 C -6.8438 15.2069 0.0 0
M  V30 39 C -6.8872 12.2263 0.0 0
M  V30 40 C -8.1749 14.4834 0.0 0
M  V30 41 C -8.2183 13.0365 0.0 0
M  V30 42 C -9.5061 15.2937 0.0 0
M  V30 43 N 7.4081 -12.3854 0.0 0
M  V30 44 C 8.6524 -13.1089 0.0 0
M  V30 45 C 6.0769 -13.1089 0.0 0
M  V30 46 C 7.3647 -10.8517 0.0 0
M  V30 47 C 9.8967 -12.2986 0.0 0
M  V30 48 C 4.7458 -12.2986 0.0 0
M  V30 49 C 6.0335 -10.0414 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 5 6
M  V30 5 1 5 7
M  V30 6 2 5 8
M  V30 7 2 5 9
M  V30 8 1 10 11
M  V30 9 1 10 12
M  V30 10 2 11 13
M  V30 11 1 11 14
M  V30 12 2 12 15
M  V30 13 1 12 16
M  V30 14 1 15 17
M  V30 15 2 16 18
M  V30 16 2 17 19
M  V30 17 1 18 20
M  V30 18 1 21 22
M  V30 19 1 21 23
M  V30 20 2 22 24
M  V30 21 1 22 25
M  V30 22 2 23 26
M  V30 23 1 23 27
M  V30 24 1 26 28
M  V30 25 2 27 29
M  V30 26 2 28 30
M  V30 27 1 29 31
M  V30 28 1 32 33
M  V30 29 1 32 34
M  V30 30 2 33 35
M  V30 31 1 33 36
M  V30 32 2 34 37
M  V30 33 1 34 38
M  V30 34 1 37 39
M  V30 35 2 38 40
M  V30 36 2 39 41
M  V30 37 1 40 42
M  V30 38 1 43 44
M  V30 39 1 43 45
M  V30 40 1 43 46
M  V30 41 1 44 47
M  V30 42 1 45 48
M  V30 43 1 46 49
M  V30 44 1 13 15
M  V30 45 1 18 19
M  V30 46 1 24 26
M  V30 47 1 29 30
M  V30 48 1 35 37
M  V30 49 1 40 41
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00072001.cdx

>  <name>
US20220000799A1-20220106-C00047

>  <Row No>
871

$$$$
US20220000799A1-20220106-C00048
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 52 53 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 F -1.4431 0.8284 0.0 0
M  V30 3 O -1.1892 -1.109 0.0 0
M  V30 4 O 1.109 -1.109 0.0 0
M  V30 5 O 1.3629 0.8284 0.0 0
M  V30 6 C 2.7259 0.0801 0.0 0
M  V30 7 C 2.6858 -1.4966 0.0 0
M  V30 8 C 4.0889 0.9086 0.0 0
M  V30 9 C 4.0488 -2.2449 0.0 0
M  V30 10 C 5.4519 0.1603 0.0 0
M  V30 11 C 5.4118 -1.4164 0.0 0
M  V30 12 N 6.7748 -2.1647 0.0 0
M  V30 13 C 8.1378 -1.3362 0.0 0
M  V30 14 O 8.0977 0.3207 0.0 0
M  V30 15 N 9.5008 -2.0845 0.0 0
M  V30 16 C 10.8638 -1.256 0.0 0
M  V30 17 C 12.2267 -2.0043 0.0 0
M  V30 18 C 10.8237 0.4008 0.0 0
M  V30 19 C 13.5897 -1.1759 0.0 0
M  V30 20 C 12.1867 1.2293 0.0 0
M  V30 21 N 13.5496 0.481 0.0 0
M  V30 22 C 14.9126 1.3095 0.0 0
M  V30 23 O 14.8725 2.9665 0.0 0
M  V30 24 C 16.2756 0.5612 0.0 0 CFG=2
M  V30 25 C 17.6386 1.3897 0.0 0
M  V30 26 C 16.2355 -1.0155 0.0 0
M  V30 27 C 19.0016 0.6414 0.0 0
M  V30 28 S -0.9621 12.6143 0.0 0
M  V30 29 F -2.2315 13.3492 0.0 0
M  V30 30 O -2.0177 11.6388 0.0 0
M  V30 31 O 0.0133 11.6388 0.0 0
M  V30 32 O 0.2271 13.3492 0.0 0
M  V30 33 C 1.4164 12.6944 0.0 0
M  V30 34 C 1.3763 11.3181 0.0 0
M  V30 35 C 2.6057 13.4294 0.0 0
M  V30 36 C 2.5656 10.6633 0.0 0
M  V30 37 C 3.7949 12.7746 0.0 0
M  V30 38 C 3.7548 11.3983 0.0 0
M  V30 39 N 4.9441 10.7435 0.0 0
M  V30 40 O 13.4695 11.4384 0.0 0
M  V30 41 C 13.4294 10.062 0.0 0
M  V30 42 N 12.1599 9.4072 0.0 0
M  V30 43 C 14.6187 9.4072 0.0 0 CFG=2
M  V30 44 C 10.8905 10.1422 0.0 0
M  V30 45 C 12.1198 8.0309 0.0 0
M  V30 46 C 15.8079 10.1422 0.0 0
M  V30 47 C 14.5786 8.0309 0.0 0
M  V30 48 C 9.621 9.4874 0.0 0
M  V30 49 C 10.8504 7.3761 0.0 0
M  V30 50 C 16.9972 9.4874 0.0 0
M  V30 51 C 9.5809 8.1111 0.0 0
M  V30 52 N 8.3115 7.4563 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 2 6 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 2 9 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 15 16
M  V30 16 1 16 17
M  V30 17 1 16 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 1 19 21
M  V30 21 1 21 22
M  V30 22 2 22 23
M  V30 23 1 22 24
M  V30 24 1 24 25
M  V30 25 1 24 26 CFG=3
M  V30 26 1 25 27
M  V30 27 1 28 29
M  V30 28 2 28 30
M  V30 29 2 28 31
M  V30 30 1 28 32
M  V30 31 1 32 33
M  V30 32 2 33 34
M  V30 33 1 33 35
M  V30 34 1 34 36
M  V30 35 2 35 37
M  V30 36 2 36 38
M  V30 37 1 38 39
M  V30 38 2 40 41
M  V30 39 1 41 42
M  V30 40 1 41 43
M  V30 41 1 42 44
M  V30 42 1 42 45
M  V30 43 1 43 46
M  V30 44 1 43 47 CFG=3
M  V30 45 1 44 48
M  V30 46 1 45 49
M  V30 47 1 46 50
M  V30 48 1 48 51
M  V30 49 1 51 52
M  V30 50 1 10 11
M  V30 51 1 20 21
M  V30 52 1 37 38
M  V30 53 1 49 51
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 24 43)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00073001.cdx

>  <name>
US20220000799A1-20220106-C00048

>  <Row No>
872

$$$$
US20220000799A1-20220106-C00049
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 74 74 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.831 -1.2339 0.0 0
M  V30 3 O 1.4353 0.0755 0.0 0
M  V30 4 O -0.831 1.385 0.0 0
M  V30 5 S 2.216 10.6772 0.0 0
M  V30 6 F 0.831 9.9973 0.0 0
M  V30 7 O 2.8959 9.4433 0.0 0
M  V30 8 O 1.385 12.0622 0.0 0
M  V30 9 O 3.4499 11.5082 0.0 0
M  V30 10 C 3.3744 13.0947 0.0 0
M  V30 11 C 1.9893 13.9257 0.0 0
M  V30 12 C 4.6083 13.9257 0.0 0
M  V30 13 C 1.9138 15.5122 0.0 0
M  V30 14 C 4.5328 15.5122 0.0 0
M  V30 15 C 3.1477 16.3432 0.0 0
M  V30 16 N 3.0722 17.9297 0.0 0
M  V30 17 C 1.6872 18.7607 0.0 0
M  V30 18 O 0.3021 19.5917 0.0 0
M  V30 19 F -4.432 2.4174 0.0 0
M  V30 20 C -3.1981 1.7375 0.0 0
M  V30 21 C -3.2736 0.3021 0.0 0
M  V30 22 C -1.9642 2.5685 0.0 0
M  V30 23 C -2.0397 -0.3777 0.0 0
M  V30 24 C -0.7302 1.8886 0.0 0
M  V30 25 C -0.8058 0.4532 0.0 0
M  V30 26 N 0.428 -0.2266 0.0 0
M  V30 27 C 1.662 0.6043 0.0 0
M  V30 28 O 1.5864 2.1908 0.0 0
M  V30 29 N 2.8959 -0.0755 0.0 0
M  V30 30 C 4.1298 0.7554 0.0 0
M  V30 31 C 5.3638 0.0755 0.0 0
M  V30 32 C 4.0543 2.3419 0.0 0
M  V30 33 C 6.5977 0.9065 0.0 0
M  V30 34 C 5.2882 3.1729 0.0 0
M  V30 35 N 6.5221 2.493 0.0 0
M  V30 36 C 7.7561 3.324 0.0 0
M  V30 37 O 7.6805 4.9105 0.0 0
M  V30 38 C 8.99 2.6441 0.0 0
M  V30 39 C 10.2239 3.4751 0.0 0
M  V30 40 F -0.6043 18.937 0.0 0
M  V30 41 C -0.6799 17.5016 0.0 0
M  V30 42 F -2.0649 18.3326 0.0 0
M  V30 43 F 0.554 18.3326 0.0 0
M  V30 44 C -0.7554 16.0662 0.0 0
M  V30 45 O 0.4784 15.3863 0.0 0
M  V30 46 N -2.1404 15.3863 0.0 0
M  V30 47 C -2.216 13.9509 0.0 0
M  V30 48 C -3.601 13.271 0.0 0
M  V30 49 C -0.9821 13.271 0.0 0
M  V30 50 C -3.6766 11.8356 0.0 0
M  V30 51 C -1.0576 11.8356 0.0 0
M  V30 52 N -2.4426 11.1557 0.0 0
M  V30 53 C -2.5182 9.7203 0.0 0
M  V30 54 O -1.2842 9.0404 0.0 0
M  V30 55 C -3.9032 9.0404 0.0 0
M  V30 56 C -5.2882 9.8714 0.0 0
M  V30 57 O -9.0656 25.7866 0.0 0
M  V30 58 C -7.8316 26.6176 0.0 0
M  V30 59 O -7.9072 28.2041 0.0 0
M  V30 60 N -6.5977 25.9376 0.0 0
M  V30 61 C -9.2922 29.0351 0.0 0
M  V30 62 C -6.6732 24.5023 0.0 0
M  V30 63 C -9.3677 30.6215 0.0 0
M  V30 64 C -10.6772 29.8661 0.0 0
M  V30 65 C -10.6772 28.3551 0.0 0
M  V30 66 C -8.0583 23.8223 0.0 0
M  V30 67 C -5.4393 23.8223 0.0 0
M  V30 68 C -8.1338 22.387 0.0 0
M  V30 69 C -5.5149 22.387 0.0 0
M  V30 70 N -6.8999 21.707 0.0 0
M  V30 71 C -6.9754 20.2716 0.0 0
M  V30 72 O -5.7415 19.5917 0.0 0
M  V30 73 C -8.3605 19.5917 0.0 0
M  V30 74 C -9.7455 20.4227 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 5 6
M  V30 5 2 5 7
M  V30 6 2 5 8
M  V30 7 1 5 9
M  V30 8 1 9 10
M  V30 9 2 10 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 2 12 14
M  V30 13 2 13 15
M  V30 14 1 15 16
M  V30 15 2 16 17
M  V30 16 2 17 18
M  V30 17 1 19 20
M  V30 18 2 20 21
M  V30 19 1 20 22
M  V30 20 1 21 23
M  V30 21 2 22 24
M  V30 22 2 23 25
M  V30 23 1 25 26
M  V30 24 1 26 27
M  V30 25 2 27 28
M  V30 26 1 27 29
M  V30 27 1 29 30
M  V30 28 1 30 31
M  V30 29 1 30 32
M  V30 30 1 31 33
M  V30 31 1 32 34
M  V30 32 1 33 35
M  V30 33 1 35 36
M  V30 34 2 36 37
M  V30 35 1 36 38
M  V30 36 1 38 39
M  V30 37 1 40 41
M  V30 38 1 41 42
M  V30 39 1 41 43
M  V30 40 1 41 44
M  V30 41 2 44 45
M  V30 42 1 44 46
M  V30 43 1 46 47
M  V30 44 1 47 48
M  V30 45 1 47 49
M  V30 46 1 48 50
M  V30 47 1 49 51
M  V30 48 1 50 52
M  V30 49 1 52 53
M  V30 50 2 53 54
M  V30 51 1 53 55
M  V30 52 1 55 56
M  V30 53 2 57 58
M  V30 54 1 58 59
M  V30 55 1 58 60
M  V30 56 1 59 61
M  V30 57 1 60 62
M  V30 58 1 61 63
M  V30 59 1 61 64
M  V30 60 1 61 65
M  V30 61 1 62 66
M  V30 62 1 62 67
M  V30 63 1 66 68
M  V30 64 1 67 69
M  V30 65 1 68 70
M  V30 66 1 70 71
M  V30 67 2 71 72
M  V30 68 1 71 73
M  V30 69 1 73 74
M  V30 70 1 14 15
M  V30 71 1 24 25
M  V30 72 1 34 35
M  V30 73 1 51 52
M  V30 74 1 69 70
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00074001.cdx

>  <name>
US20220000799A1-20220106-C00049

>  <Row No>
873

$$$$
US20220000799A1-20220106-C00050
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 63 64 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.8624 -1.3211 0.0 0
M  V30 3 O 1.5413 0.055 0.0 0
M  V30 4 O -0.8624 1.4312 0.0 0
M  V30 5 S -7.4865 14.6794 0.0 0
M  V30 6 F -8.9177 13.9271 0.0 0
M  V30 7 O -6.7342 13.3583 0.0 0
M  V30 8 O -8.3489 16.1107 0.0 0
M  V30 9 O -6.1653 15.5418 0.0 0
M  V30 10 C -6.2204 17.1933 0.0 0
M  V30 11 C -7.6516 18.0557 0.0 0
M  V30 12 C -4.8992 18.0557 0.0 0
M  V30 13 C -7.7067 19.7071 0.0 0
M  V30 14 C -4.9543 19.7071 0.0 0
M  V30 15 C -6.3855 20.5695 0.0 0
M  V30 16 N -6.4406 22.221 0.0 0
M  V30 17 C -7.8718 23.0834 0.0 0
M  V30 18 O -9.3031 23.9458 0.0 0
M  V30 19 F -4.6974 2.4955 0.0 0
M  V30 20 C -3.5597 1.8349 0.0 0
M  V30 21 C -3.6148 0.4954 0.0 0
M  V30 22 C -2.4037 2.6056 0.0 0
M  V30 23 C -2.4771 -0.1651 0.0 0
M  V30 24 C -1.2661 1.945 0.0 0
M  V30 25 C -1.3211 0.6055 0.0 0
M  V30 26 N -0.1834 -0.055 0.0 0
M  V30 27 C 0.9541 0.7156 0.0 0
M  V30 28 O 0.8991 2.1652 0.0 0
M  V30 29 N 2.0918 0.055 0.0 0
M  V30 30 C 3.2478 0.8257 0.0 0
M  V30 31 C 4.3854 0.1651 0.0 0
M  V30 32 C 3.1927 2.2753 0.0 0
M  V30 33 C 5.5231 0.9358 0.0 0
M  V30 34 C 4.3487 3.0459 0.0 0
M  V30 35 C 5.468 2.3854 0.0 0
M  V30 36 O 6.6057 3.156 0.0 0
M  V30 37 C 7.7617 2.4955 0.0 0
M  V30 38 C 7.7067 1.156 0.0 0
M  V30 39 C 8.8994 3.2661 0.0 0
M  V30 40 C 8.8443 0.4954 0.0 0
M  V30 41 C 10.037 2.6056 0.0 0
M  V30 42 C 10.0003 1.2661 0.0 0
M  V30 43 C 11.138 0.6055 0.0 0
M  V30 44 O 12.4591 1.4679 0.0 0
M  V30 45 O 11.0829 -0.9358 0.0 0
M  V30 46 O -4.1102 3.2294 0.0 0
M  V30 47 C -3.3579 4.6607 0.0 0
M  V30 48 O -4.2203 6.0919 0.0 0
M  V30 49 C -3.468 7.5232 0.0 0
M  V30 50 C -4.3304 8.9544 0.0 0
M  V30 51 C -1.9266 7.5782 0.0 0
M  V30 52 C -3.5781 10.3857 0.0 0
M  V30 53 C -1.1743 9.0095 0.0 0
M  V30 54 C -2.0367 10.4407 0.0 0
M  V30 55 O -1.2844 11.872 0.0 0
M  V30 56 C 0.2568 11.927 0.0 0 CFG=1
M  V30 57 C 1.0092 10.6059 0.0 0
M  V30 58 C 1.0092 13.3583 0.0 0
M  V30 59 C 2.5505 10.6609 0.0 0
M  V30 60 C 2.5505 13.4133 0.0 0
M  V30 61 C 3.3028 12.0922 0.0 0 CFG=1
M  V30 62 N 4.8442 12.1472 0.0 0
M  V30 63 C -3.523 18.7897 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 5 6
M  V30 5 2 5 7
M  V30 6 2 5 8
M  V30 7 1 5 9
M  V30 8 1 9 10
M  V30 9 2 10 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 2 12 14
M  V30 13 2 13 15
M  V30 14 1 15 16
M  V30 15 2 16 17
M  V30 16 2 17 18
M  V30 17 1 19 20
M  V30 18 2 20 21
M  V30 19 1 20 22
M  V30 20 1 21 23
M  V30 21 2 22 24
M  V30 22 2 23 25
M  V30 23 1 25 26
M  V30 24 1 26 27
M  V30 25 2 27 28
M  V30 26 1 27 29
M  V30 27 1 29 30
M  V30 28 1 30 31
M  V30 29 1 30 32
M  V30 30 1 31 33
M  V30 31 1 32 34
M  V30 32 1 33 35
M  V30 33 1 35 36
M  V30 34 1 36 37
M  V30 35 2 37 38
M  V30 36 1 37 39
M  V30 37 1 38 40
M  V30 38 2 39 41
M  V30 39 2 40 42
M  V30 40 1 42 43
M  V30 41 2 43 44
M  V30 42 1 43 45
M  V30 43 2 46 47
M  V30 44 1 47 48
M  V30 45 1 48 49
M  V30 46 2 49 50
M  V30 47 1 49 51
M  V30 48 1 50 52
M  V30 49 2 51 53
M  V30 50 2 52 54
M  V30 51 1 54 55
M  V30 52 1 56 55 CFG=3
M  V30 53 1 56 57
M  V30 54 1 56 58
M  V30 55 1 57 59
M  V30 56 1 58 60
M  V30 57 1 59 61
M  V30 58 1 61 62 CFG=1
M  V30 59 1 14 15
M  V30 60 1 24 25
M  V30 61 1 34 35
M  V30 62 1 41 42
M  V30 63 1 53 54
M  V30 64 1 60 61
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STEABS ATOMS=(2 56 61)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00075001.cdx

>  <name>
US20220000799A1-20220106-C00050

>  <Row No>
874

$$$$
US20220000799A1-20220106-C00051
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 34 34 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 F -1.3104 -0.7067 0.0 0
M  V30 3 O 0.7067 -1.2221 0.0 0
M  V30 4 O -0.7951 1.3104 0.0 0
M  V30 5 O 1.2221 0.7951 0.0 0
M  V30 6 C 1.1779 2.3116 0.0 0
M  V30 7 C -0.1325 3.1067 0.0 0
M  V30 8 C 2.4 3.1067 0.0 0
M  V30 9 C -0.1766 4.6233 0.0 0
M  V30 10 C 2.3558 4.6233 0.0 0
M  V30 11 C 1.0454 5.4184 0.0 0
M  V30 12 N 1.0012 6.935 0.0 0
M  V30 13 C -0.3092 7.7301 0.0 0
M  V30 14 O -1.6196 8.5252 0.0 0
M  V30 15 S -10.3658 0.1177 0.0 0
M  V30 16 F -11.6762 -0.5889 0.0 0
M  V30 17 O -9.659 -1.1043 0.0 0
M  V30 18 O -11.1609 1.4282 0.0 0
M  V30 19 O -9.1437 0.9128 0.0 0
M  V30 20 C -9.1878 2.4294 0.0 0
M  V30 21 C -10.4983 3.2245 0.0 0
M  V30 22 C -7.9657 3.2245 0.0 0
M  V30 23 C -10.5425 4.7411 0.0 0
M  V30 24 C -8.0099 4.7411 0.0 0
M  V30 25 C -9.3203 5.5362 0.0 0
M  V30 26 N -9.3645 7.0528 0.0 0
M  V30 27 O -15.0775 9.1878 0.0 0
M  V30 28 C -15.1217 10.7044 0.0 0
M  V30 29 C -16.4321 11.4995 0.0 0
M  V30 30 C -13.8996 11.4995 0.0 0
M  V30 31 C -16.4763 13.0161 0.0 0
M  V30 32 C -13.9437 13.0161 0.0 0
M  V30 33 C -15.2542 13.8112 0.0 0
M  V30 34 N -15.2984 15.3278 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 2 6 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 2 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 2 13 14
M  V30 14 1 15 16
M  V30 15 2 15 17
M  V30 16 2 15 18
M  V30 17 1 15 19
M  V30 18 1 19 20
M  V30 19 2 20 21
M  V30 20 1 20 22
M  V30 21 1 21 23
M  V30 22 2 22 24
M  V30 23 2 23 25
M  V30 24 1 25 26
M  V30 25 1 27 28
M  V30 26 2 28 29
M  V30 27 1 28 30
M  V30 28 1 29 31
M  V30 29 2 30 32
M  V30 30 2 31 33
M  V30 31 1 33 34
M  V30 32 1 10 11
M  V30 33 1 24 25
M  V30 34 1 32 33
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00076001.cdx

>  <name>
US20220000799A1-20220106-C00051

>  <Row No>
875

$$$$
US20220000799A1-20220106-C00052
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 56 55 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.7712 -1.2653 0.0 0
M  V30 3 O 1.4702 0.0361 0.0 0
M  V30 4 O -0.7712 1.3376 0.0 0
M  V30 5 S -11.3764 7.0379 0.0 0
M  V30 6 F -12.7141 6.3148 0.0 0
M  V30 7 O -10.6533 5.7725 0.0 0
M  V30 8 O -12.1477 8.3756 0.0 0
M  V30 9 O -10.111 7.8092 0.0 0
M  V30 10 C -10.1472 9.3518 0.0 0
M  V30 11 C -11.4849 10.1351 0.0 0
M  V30 12 C -8.8818 10.1351 0.0 0
M  V30 13 C -11.521 11.6777 0.0 0
M  V30 14 C -8.9179 11.6777 0.0 0
M  V30 15 C -10.2556 12.461 0.0 0
M  V30 16 N -10.2918 14.0036 0.0 0
M  V30 17 C -11.6295 14.7749 0.0 0
M  V30 18 O -12.9672 15.5582 0.0 0
M  V30 19 F -4.242 2.121 0.0 0
M  V30 20 C -2.9766 1.3979 0.0 0
M  V30 21 C -3.0128 -0.0723 0.0 0
M  V30 22 C -1.7112 2.1812 0.0 0
M  V30 23 C -1.7474 -0.8074 0.0 0
M  V30 24 C -0.4458 1.4582 0.0 0
M  V30 25 C -0.482 -0.0241 0.0 0
M  V30 26 N 0.7833 -0.7592 0.0 0
M  V30 27 C 2.0487 0.0241 0.0 0
M  V30 28 O 2.0125 1.5666 0.0 0
M  V30 29 N 3.3141 -0.711 0.0 0
M  V30 30 C 4.5795 0.0723 0.0 0
M  V30 31 C 5.8448 -0.6628 0.0 0
M  V30 32 C 4.5433 1.6148 0.0 0
M  V30 33 C 7.1102 0.1205 0.0 0
M  V30 34 C 5.8087 2.3982 0.0 0
M  V30 35 N 7.0741 1.663 0.0 0
M  V30 36 C 8.3395 2.4343 0.0 0
M  V30 37 O 8.3033 3.9769 0.0 0
M  V30 38 O 9.6049 1.7112 0.0 0
M  V30 39 C 10.8702 2.4825 0.0 0
M  V30 40 C 10.8341 4.0251 0.0 0
M  V30 41 C 12.1356 3.2659 0.0 0
M  V30 42 C 12.1356 1.7594 0.0 0
M  V30 43 O -3.5671 7.2307 0.0 0
M  V30 44 C -3.6033 5.7605 0.0 0
M  V30 45 O -2.3379 5.0374 0.0 0
M  V30 46 N -4.941 5.0374 0.0 0
M  V30 47 C -1.0725 5.8087 0.0 0
M  V30 48 C -6.2787 5.8087 0.0 0
M  V30 49 C 0.1928 5.0856 0.0 0
M  V30 50 C 0.1928 6.58 0.0 0
M  V30 51 C -1.1087 7.3513 0.0 0
M  V30 52 C -6.3148 7.3513 0.0 0
M  V30 53 C -5.0495 8.1346 0.0 0 CFG=1
M  V30 54 N -5.0856 9.6772 0.0 0
M  V30 55 C -3.7841 7.4115 0.0 0
M  V30 56 C -3.8202 5.9413 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 5 6
M  V30 5 2 5 7
M  V30 6 2 5 8
M  V30 7 1 5 9
M  V30 8 1 9 10
M  V30 9 2 10 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 2 12 14
M  V30 13 2 13 15
M  V30 14 1 15 16
M  V30 15 2 16 17
M  V30 16 2 17 18
M  V30 17 1 19 20
M  V30 18 2 20 21
M  V30 19 1 20 22
M  V30 20 1 21 23
M  V30 21 2 22 24
M  V30 22 2 23 25
M  V30 23 1 25 26
M  V30 24 1 26 27
M  V30 25 2 27 28
M  V30 26 1 27 29
M  V30 27 1 29 30
M  V30 28 1 30 31
M  V30 29 1 30 32
M  V30 30 1 31 33
M  V30 31 1 32 34
M  V30 32 1 33 35
M  V30 33 1 35 36
M  V30 34 2 36 37
M  V30 35 1 36 38
M  V30 36 1 38 39
M  V30 37 1 39 40
M  V30 38 1 39 41
M  V30 39 1 39 42
M  V30 40 2 43 44
M  V30 41 1 44 45
M  V30 42 1 44 46
M  V30 43 1 45 47
M  V30 44 1 46 48
M  V30 45 1 47 49
M  V30 46 1 47 50
M  V30 47 1 47 51
M  V30 48 1 48 52
M  V30 49 1 52 53
M  V30 50 1 53 54 CFG=1
M  V30 51 1 53 55
M  V30 52 1 55 56
M  V30 53 1 14 15
M  V30 54 1 24 25
M  V30 55 1 34 35
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 53)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00077001.cdx

>  <name>
US20220000799A1-20220106-C00052

>  <Row No>
876

$$$$
US20220000799A1-20220106-C00053
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.7702 -1.2442 0.0 0
M  V30 3 O 1.4457 0.0355 0.0 0
M  V30 4 O -0.7702 1.3153 0.0 0
M  V30 5 S 6.0672 2.0856 0.0 0
M  V30 6 O 6.7782 3.4009 0.0 0
M  V30 7 O 5.2851 0.8413 0.0 0
M  V30 8 N 7.3114 1.3746 0.0 0
M  V30 9 C 4.7518 2.8677 0.0 0
M  V30 10 C 7.2759 -0.0711 0.0 0
M  V30 11 C 5.9961 2.1448 0.0 0
M  V30 12 C 5.9605 -0.7939 0.0 0
M  V30 13 C 4.6807 1.4338 0.0 0
M  V30 14 C 4.6452 -0.0237 0.0 0
M  V30 15 N 3.3298 -0.7465 0.0 0
M  V30 16 C 2.0145 0.0355 0.0 0
M  V30 17 O 1.9789 1.5523 0.0 0
M  V30 18 N 0.6991 -0.6873 0.0 0
M  V30 19 C -0.6162 0.0948 0.0 0
M  V30 20 C -1.9315 -0.628 0.0 0
M  V30 21 C -0.6517 1.6116 0.0 0
M  V30 22 C -3.2469 0.154 0.0 0
M  V30 23 C -1.9671 2.3818 0.0 0
M  V30 24 C -3.2824 1.6708 0.0 0
M  V30 25 F -4.5978 2.4411 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 2 5 6
M  V30 5 2 5 7
M  V30 6 1 5 8
M  V30 7 1 5 9
M  V30 8 1 8 10
M  V30 9 1 8 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 1 12 14
M  V30 13 1 14 15
M  V30 14 1 15 16
M  V30 15 2 16 17
M  V30 16 1 16 18
M  V30 17 1 18 19
M  V30 18 2 19 20
M  V30 19 1 19 21
M  V30 20 1 20 22
M  V30 21 2 21 23
M  V30 22 2 22 24
M  V30 23 1 24 25
M  V30 24 1 13 14
M  V30 25 1 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00078001.cdx

>  <name>
US20220000799A1-20220106-C00053

>  <Row No>
877

$$$$
US20220000799A1-20220106-C00055
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.7702 -1.2442 0.0 0
M  V30 3 O 1.4457 0.0355 0.0 0
M  V30 4 O -0.7702 1.3153 0.0 0
M  V30 5 S 6.0672 2.0856 0.0 0
M  V30 6 F 4.7518 2.8677 0.0 0
M  V30 7 O 6.7782 3.4009 0.0 0
M  V30 8 O 5.2851 0.8413 0.0 0
M  V30 9 N 7.3114 1.3746 0.0 0
M  V30 10 C 7.2759 -0.0711 0.0 0
M  V30 11 C 5.9961 2.1448 0.0 0
M  V30 12 C 5.9605 -0.7939 0.0 0
M  V30 13 C 4.6807 1.4338 0.0 0
M  V30 14 C 4.6452 -0.0237 0.0 0
M  V30 15 N 3.3298 -0.7465 0.0 0
M  V30 16 C 2.0145 0.0355 0.0 0
M  V30 17 O 1.9789 1.5523 0.0 0
M  V30 18 N 0.6991 -0.6873 0.0 0
M  V30 19 C -0.6162 0.0948 0.0 0
M  V30 20 C -1.9315 -0.628 0.0 0
M  V30 21 C -0.6517 1.6116 0.0 0
M  V30 22 C -3.2469 0.154 0.0 0
M  V30 23 C -1.9671 2.3818 0.0 0
M  V30 24 C -3.2824 1.6708 0.0 0
M  V30 25 F -4.5978 2.4411 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 5 6
M  V30 5 2 5 7
M  V30 6 2 5 8
M  V30 7 1 5 9
M  V30 8 1 9 10
M  V30 9 1 9 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 1 12 14
M  V30 13 1 14 15
M  V30 14 1 15 16
M  V30 15 2 16 17
M  V30 16 1 16 18
M  V30 17 1 18 19
M  V30 18 2 19 20
M  V30 19 1 19 21
M  V30 20 1 20 22
M  V30 21 2 21 23
M  V30 22 2 22 24
M  V30 23 1 24 25
M  V30 24 1 13 14
M  V30 25 1 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00079001.cdx

>  <name>
US20220000799A1-20220106-C00055

>  <Row No>
878

$$$$
US20220000799A1-20220106-C00056
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 F -1.3159 0.7587 0.0 0
M  V30 3 O 0.7231 1.3159 0.0 0
M  V30 4 O -0.7587 -1.2448 0.0 0
M  V30 5 N 1.2448 -0.7113 0.0 0
M  V30 6 C 1.2092 -2.1577 0.0 0
M  V30 7 C -0.0711 0.0474 0.0 0
M  V30 8 C -0.1067 -2.869 0.0 0
M  V30 9 C -1.3871 -0.6639 0.0 0
M  V30 10 C -1.4226 -2.0984 0.0 0
M  V30 11 N -2.7386 -2.8097 0.0 0
M  V30 12 C -4.0546 -2.0391 0.0 0
M  V30 13 O -4.0901 -0.5216 0.0 0
M  V30 14 N -5.3706 -2.7505 0.0 0
M  V30 15 C -6.6865 -1.9798 0.0 0
M  V30 16 C -8.0025 -2.6912 0.0 0
M  V30 17 C -6.7221 -0.4623 0.0 0
M  V30 18 C -9.3185 -1.9206 0.0 0
M  V30 19 C -8.0381 0.2963 0.0 0
M  V30 20 C -9.354 -0.403 0.0 0
M  V30 21 C -10.67 0.3556 0.0 0
M  V30 22 C -11.986 1.1262 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 2 17 19
M  V30 19 2 18 20
M  V30 20 1 20 21
M  V30 21 3 21 22
M  V30 22 1 9 10
M  V30 23 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00081001.cdx

>  <name>
US20220000799A1-20220106-C00056

>  <Row No>
879

$$$$
US20220000799A1-20220106-C00057
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 O -0.7702 -1.2442 0.0 0
M  V30 3 O 1.4457 0.0355 0.0 0
M  V30 4 O -0.7702 1.3153 0.0 0
M  V30 5 S 6.0672 2.0856 0.0 0
M  V30 6 F 4.7518 2.8677 0.0 0
M  V30 7 O 6.7782 3.4009 0.0 0
M  V30 8 O 5.2851 0.8413 0.0 0
M  V30 9 N 7.3114 1.3746 0.0 0
M  V30 10 C 7.2759 -0.0711 0.0 0
M  V30 11 C 5.9961 2.1448 0.0 0
M  V30 12 C 5.9605 -0.7939 0.0 0
M  V30 13 C 4.6807 1.4338 0.0 0
M  V30 14 C 4.6452 -0.0237 0.0 0
M  V30 15 N 3.3298 -0.7465 0.0 0
M  V30 16 C 2.0145 0.0355 0.0 0
M  V30 17 O 1.9789 1.5523 0.0 0
M  V30 18 N 0.6991 -0.6873 0.0 0
M  V30 19 C -0.6162 0.0948 0.0 0
M  V30 20 C -1.9315 -0.628 0.0 0
M  V30 21 C -0.6517 1.6116 0.0 0
M  V30 22 C -3.2469 0.154 0.0 0
M  V30 23 C -1.9671 2.3818 0.0 0
M  V30 24 C -3.2824 1.6708 0.0 0
M  V30 25 F -4.5978 2.4411 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 5 6
M  V30 5 2 5 7
M  V30 6 2 5 8
M  V30 7 1 5 9
M  V30 8 1 9 10
M  V30 9 1 9 11
M  V30 10 1 10 12
M  V30 11 1 11 13
M  V30 12 1 12 14
M  V30 13 1 14 15
M  V30 14 1 15 16
M  V30 15 2 16 17
M  V30 16 1 16 18
M  V30 17 1 18 19
M  V30 18 2 19 20
M  V30 19 1 19 21
M  V30 20 1 20 22
M  V30 21 2 21 23
M  V30 22 2 22 24
M  V30 23 1 24 25
M  V30 24 1 13 14
M  V30 25 1 23 24
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00082001.cdx

>  <name>
US20220000799A1-20220106-C00057

>  <Row No>
880

$$$$
US20220000799A1-20220106-C00058
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 46 47 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 F 1.2543 -0.7167 0.0 0
M  V30 3 O 0.7287 1.326 0.0 0
M  V30 4 O -0.7645 -1.2543 0.0 0
M  V30 5 C -1.326 0.7765 0.0 0
M  V30 6 C -2.652 0.0477 0.0 0
M  V30 7 N -3.9781 0.8242 0.0 0
M  V30 8 C -5.3041 0.0955 0.0 0
M  V30 9 C -4.0139 2.3534 0.0 0
M  V30 10 C -6.6301 0.872 0.0 0
M  V30 11 C -5.3399 3.1299 0.0 0
M  V30 12 C -6.666 2.4011 0.0 0
M  V30 13 C -7.992 3.1777 0.0 0
M  V30 14 C -9.318 2.4489 0.0 0
M  V30 15 O -9.3539 0.9915 0.0 0
M  V30 16 C -10.6441 3.2135 0.0 0
M  V30 17 C -11.9701 2.4848 0.0 0
M  V30 18 C -13.2961 3.2493 0.0 0
M  V30 19 C -12.0059 1.0273 0.0 0
M  V30 20 C -14.6222 2.5206 0.0 0
M  V30 21 C -13.332 0.2986 0.0 0
M  V30 22 C -14.658 1.0632 0.0 0
M  V30 23 C -15.984 0.3344 0.0 0
M  V30 24 S -2.1981 10.2259 0.0 0
M  V30 25 F -0.9437 9.4972 0.0 0
M  V30 26 O -1.4693 11.552 0.0 0
M  V30 27 O -2.9746 8.9716 0.0 0
M  V30 28 C -3.5241 10.9905 0.0 0
M  V30 29 C -4.8501 10.2737 0.0 0
M  V30 30 O -11.2772 7.9323 0.0 0
M  V30 31 C -11.3131 9.4614 0.0 0
M  V30 32 C -12.6391 10.2259 0.0 0
M  V30 33 C -10.0587 10.2259 0.0 0
M  V30 34 C -13.9651 9.5092 0.0 0
M  V30 35 C -8.8043 9.5092 0.0 0
M  V30 36 C -15.2912 10.2857 0.0 0
M  V30 37 C -14.001 8.0517 0.0 0
M  V30 38 C -8.8402 8.0517 0.0 0
M  V30 39 C -7.55 10.2857 0.0 0
M  V30 40 C -16.6172 9.5689 0.0 0
M  V30 41 C -15.327 7.323 0.0 0
M  V30 42 C -7.5858 7.323 0.0 0
M  V30 43 C -6.2956 9.5689 0.0 0
M  V30 44 C -16.653 8.1115 0.0 0
M  V30 45 N -6.3315 8.0995 0.0 0
M  V30 46 C -17.9791 7.3827 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 1 6 7
M  V30 7 1 7 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 1 12 13
M  V30 13 1 13 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 16 17
M  V30 17 2 17 18
M  V30 18 1 17 19
M  V30 19 1 18 20
M  V30 20 2 19 21
M  V30 21 2 20 22
M  V30 22 1 22 23
M  V30 23 1 24 25
M  V30 24 2 24 26
M  V30 25 2 24 27
M  V30 26 1 24 28
M  V30 27 1 28 29
M  V30 28 2 30 31
M  V30 29 1 31 32
M  V30 30 1 31 33
M  V30 31 1 32 34
M  V30 32 1 33 35
M  V30 33 2 34 36
M  V30 34 1 34 37
M  V30 35 1 35 38
M  V30 36 1 35 39
M  V30 37 1 36 40
M  V30 38 2 37 41
M  V30 39 1 38 42
M  V30 40 1 39 43
M  V30 41 2 40 44
M  V30 42 1 42 45
M  V30 43 1 44 46
M  V30 44 1 11 12
M  V30 45 1 21 22
M  V30 46 1 41 44
M  V30 47 1 43 45
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00083001.cdx

>  <name>
US20220000799A1-20220106-C00058

>  <Row No>
881

$$$$
US20220000799A1-20220106-C00059
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 53 54 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 S -0.1167 -12.261 0.0 0
M  V30 3 O 0.5692 -13.5163 0.0 0
M  V30 4 O 0.5692 -10.9181 0.0 0
M  V30 5 O -1.664 -12.2172 0.0 0
M  V30 6 F -3.6199 -14.7132 0.0 0
M  V30 7 C -2.3646 -13.9396 0.0 0
M  V30 8 C -1.1093 -14.6257 0.0 0
M  V30 9 C -2.4084 -12.3924 0.0 0
M  V30 10 C 0.1459 -13.852 0.0 0
M  V30 11 C -1.1531 -11.6188 0.0 0
M  V30 12 C 0.1021 -12.3048 0.0 0
M  V30 13 C 1.4012 -14.5381 0.0 0
M  V30 14 C 1.3574 -11.5312 0.0 0
M  V30 15 C 2.6565 -13.7645 0.0 0
M  V30 16 C 2.6127 -12.2172 0.0 0
M  V30 17 C 3.868 -11.4436 0.0 0 CFG=2
M  V30 18 C 5.1233 -12.1297 0.0 0
M  V30 19 C 3.8242 -9.8964 0.0 0
M  V30 20 O 6.3786 -11.356 0.0 0
M  V30 21 O 5.0795 -13.5893 0.0 0
M  V30 22 O 0.8174 -4.087 0.0 0
M  V30 23 C -0.5254 -4.773 0.0 0
M  V30 24 O -0.5692 -6.2327 0.0 0
M  V30 25 C -1.8683 -3.9994 0.0 0 CFG=1
M  V30 26 C -3.2112 -4.6854 0.0 0
M  V30 27 C -1.9121 -2.4522 0.0 0
M  V30 28 C -4.5541 -3.9118 0.0 0
M  V30 29 C -3.255 -6.1451 0.0 0
M  V30 30 C -5.8969 -4.5979 0.0 0
M  V30 31 C -4.5979 -6.8311 0.0 0
M  V30 32 C -5.9407 -6.0575 0.0 0
M  V30 33 C -7.2398 -3.8242 0.0 0
M  V30 34 C -7.2836 -6.7435 0.0 0
M  V30 35 C -8.5827 -4.5103 0.0 0
M  V30 36 C -8.6265 -5.9699 0.0 0
M  V30 37 O -9.9694 -6.656 0.0 0
M  V30 38 O -1.518 1.6348 0.0 0
M  V30 39 C -2.8609 0.9487 0.0 0
M  V30 40 O -2.9047 -0.5108 0.0 0
M  V30 41 C -4.2037 1.7223 0.0 0 CFG=1
M  V30 42 C -5.5466 1.0363 0.0 0
M  V30 43 C -4.2475 3.2696 0.0 0
M  V30 44 C -6.8895 1.8099 0.0 0
M  V30 45 C -5.5904 -0.4232 0.0 0
M  V30 46 C -8.2324 1.1239 0.0 0
M  V30 47 C -6.9333 -1.1093 0.0 0
M  V30 48 C -8.2762 -0.3357 0.0 0
M  V30 49 C -9.5753 1.8975 0.0 0
M  V30 50 C -9.6191 -1.0217 0.0 0
M  V30 51 C -10.9181 1.2115 0.0 0
M  V30 52 C -10.9619 -0.2481 0.0 0
M  V30 53 C -12.3048 -0.9341 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 2 3
M  V30 2 2 2 4
M  V30 3 2 2 5
M  V30 4 1 6 7
M  V30 5 2 7 8
M  V30 6 1 7 9
M  V30 7 1 8 10
M  V30 8 2 9 11
M  V30 9 1 10 12
M  V30 10 2 10 13
M  V30 11 2 12 14
M  V30 12 1 13 15
M  V30 13 1 14 16
M  V30 14 1 16 17
M  V30 15 1 17 18
M  V30 16 1 17 19 CFG=1
M  V30 17 2 18 20
M  V30 18 1 18 21
M  V30 19 2 22 23
M  V30 20 1 23 24
M  V30 21 1 23 25
M  V30 22 1 25 26
M  V30 23 1 25 27 CFG=1
M  V30 24 2 26 28
M  V30 25 1 26 29
M  V30 26 1 28 30
M  V30 27 2 29 31
M  V30 28 1 30 32
M  V30 29 2 30 33
M  V30 30 2 32 34
M  V30 31 1 33 35
M  V30 32 1 34 36
M  V30 33 1 36 37
M  V30 34 2 38 39
M  V30 35 1 39 40
M  V30 36 1 39 41
M  V30 37 1 41 42
M  V30 38 1 41 43 CFG=1
M  V30 39 2 42 44
M  V30 40 1 42 45
M  V30 41 1 44 46
M  V30 42 2 45 47
M  V30 43 1 46 48
M  V30 44 2 46 49
M  V30 45 2 48 50
M  V30 46 1 49 51
M  V30 47 1 50 52
M  V30 48 1 52 53
M  V30 49 1 11 12
M  V30 50 2 15 16
M  V30 51 1 31 32
M  V30 52 2 35 36
M  V30 53 1 47 48
M  V30 54 2 51 52
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 17 25 41)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00084001.cdx

>  <name>
US20220000799A1-20220106-C00059

>  <Row No>
882

$$$$
US20220000799A1-20220106-C00060
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 F -1.3346 0.7695 0.0 0
M  V30 3 O 0.7214 1.3346 0.0 0
M  V30 4 O -0.7695 -1.2625 0.0 0
M  V30 5 O 1.2625 -0.7334 0.0 0
M  V30 6 C 1.2264 -2.2003 0.0 0
M  V30 7 C -0.1082 -2.9217 0.0 0
M  V30 8 C 2.4889 -2.9217 0.0 0
M  V30 9 C -0.1442 -4.3887 0.0 0
M  V30 10 C 2.4528 -4.3887 0.0 0
M  V30 11 C 1.1182 -5.1101 0.0 0
M  V30 12 N 1.0821 -6.577 0.0 0
M  V30 13 C 2.3446 -7.3104 0.0 0
M  V30 14 O 2.3085 -8.7774 0.0 0
M  V30 15 C 3.6071 -6.5289 0.0 0
M  V30 16 O -5.1942 -8.6571 0.0 0
M  V30 17 C -5.2303 -7.1181 0.0 0
M  V30 18 N -6.565 -6.3365 0.0 0
M  V30 19 C -3.9678 -6.3365 0.0 0
M  V30 20 C -6.601 -4.7975 0.0 0
M  V30 21 C -7.9357 -4.0159 0.0 0
M  V30 22 C -5.3385 -4.0159 0.0 0
M  V30 23 C -7.9718 -2.4769 0.0 0
M  V30 24 C -5.3746 -2.4769 0.0 0
M  V30 25 C -6.7093 -1.7073 0.0 0
M  V30 26 O -6.7453 -0.1683 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 1 3
M  V30 3 2 1 4
M  V30 4 1 1 5
M  V30 5 1 5 6
M  V30 6 2 6 7
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 2 9 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 2 16 17
M  V30 16 1 17 18
M  V30 17 1 17 19
M  V30 18 1 18 20
M  V30 19 2 20 21
M  V30 20 1 20 22
M  V30 21 1 21 23
M  V30 22 2 22 24
M  V30 23 2 23 25
M  V30 24 1 25 26
M  V30 25 1 10 11
M  V30 26 1 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00085001.cdx

>  <name>
US20220000799A1-20220106-C00060

>  <Row No>
883

$$$$
US20220000800A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 24 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2601 0.7681 0.0 0
M  V30 3 C 1.2241 2.3043 0.0 0
M  V30 4 C 2.5203 0.036 0.0 0
M  V30 5 C 2.4843 3.0724 0.0 0
M  V30 6 C -0.108 3.0724 0.0 0 CFG=2
M  V30 7 C 3.7805 0.8041 0.0 0
M  V30 8 O 2.4483 4.6087 0.0 0
M  V30 9 C 3.7445 2.3523 0.0 0
M  V30 10 C 0.612 4.4046 0.0 0
M  V30 11 C -1.6442 3.1084 0.0 0 CFG=2
M  V30 12 C 5.0407 0.072 0.0 0
M  V30 13 C -0.156 5.7368 0.0 0
M  V30 14 C -2.4243 1.8482 0.0 0
M  V30 15 C -2.4243 4.4406 0.0 0
M  V30 16 C 6.3009 0.8401 0.0 0
M  V30 17 C -1.6922 5.7728 0.0 0
M  V30 18 C 0.564 7.069 0.0 0
M  V30 19 C -1.6922 0.588 0.0 0
M  V30 20 C -3.9606 1.8842 0.0 0
M  V30 21 C 7.5611 0.108 0.0 0
M  V30 22 C 8.8213 0.8761 0.0 0
M  V30 23 C 10.0815 0.144 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 6 3 CFG=1
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 5 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 2 10 13
M  V30 13 1 11 14 CFG=3
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 2 14 19
M  V30 19 1 14 20
M  V30 20 1 16 21
M  V30 21 1 21 22
M  V30 22 1 22 23
M  V30 23 1 7 9
M  V30 24 1 15 17
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 6 11)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000800A1-20220106-C00001

>  <Row No>
884

$$$$
US20220000800A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4615 0.0 0
M  V30 3 O 1.2219 -2.1803 0.0 0
M  V30 4 C -1.3657 -2.1803 0.0 0
M  V30 5 C -2.6954 -1.4136 0.0 0
M  V30 6 C -1.4016 -3.6418 0.0 0
M  V30 7 O -2.7314 0.1197 0.0 0
M  V30 8 C -4.0252 -2.1324 0.0 0
M  V30 9 C -2.7314 -4.3726 0.0 0
M  V30 10 C -0.1437 -4.3726 0.0 0
M  V30 11 C -4.0611 -3.5939 0.0 0
M  V30 12 C -5.3549 -1.3657 0.0 0 CFG=2
M  V30 13 C 1.1141 -3.6059 0.0 0
M  V30 14 O -5.3909 -4.3247 0.0 0
M  V30 15 C -4.6362 -0.0359 0.0 0
M  V30 16 C -6.8884 -1.3297 0.0 0 CFG=2
M  V30 17 C 2.372 -4.3367 0.0 0
M  V30 18 C -5.4029 1.2938 0.0 0
M  V30 19 C -7.6671 -2.5876 0.0 0
M  V30 20 C -7.6671 0.0 0.0 0
M  V30 21 C 3.6298 -3.5699 0.0 0
M  V30 22 C -6.9363 1.3297 0.0 0
M  V30 23 C -4.6841 2.6235 0.0 0
M  V30 24 C -6.9363 -3.8455 0.0 0
M  V30 25 C -9.2005 -2.5517 0.0 0
M  V30 26 C 4.8877 -4.3007 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 2 8 11
M  V30 11 1 12 8 CFG=1
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 2 15 18
M  V30 18 1 16 19 CFG=3
M  V30 19 1 16 20
M  V30 20 1 17 21
M  V30 21 1 18 22
M  V30 22 1 18 23
M  V30 23 2 19 24
M  V30 24 1 19 25
M  V30 25 1 21 26
M  V30 26 1 9 11
M  V30 27 1 20 22
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 12 16)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000800A1-20220106-C00002

>  <Row No>
885

$$$$
US20220000800A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2567 0.7659 0.0 0
M  V30 3 C 1.2207 2.2979 0.0 0
M  V30 4 C 2.5134 0.0359 0.0 0
M  V30 5 C 2.4775 3.0759 0.0 0
M  V30 6 C -0.1077 3.0759 0.0 0 CFG=2
M  V30 7 C 3.7701 0.8138 0.0 0
M  V30 8 O 2.4415 4.6079 0.0 0
M  V30 9 C 3.7342 2.3578 0.0 0
M  V30 10 C 0.6103 4.4044 0.0 0
M  V30 11 C -1.6396 3.1118 0.0 0 CFG=2
M  V30 12 C 5.0268 0.0837 0.0 0
M  V30 13 C -0.1555 5.7329 0.0 0
M  V30 14 C -2.4176 1.8551 0.0 0
M  V30 15 C -2.4176 4.4403 0.0 0
M  V30 16 C 6.2835 0.8617 0.0 0
M  V30 17 C -1.6875 5.7688 0.0 0
M  V30 18 C 0.5625 7.0614 0.0 0
M  V30 19 C -1.6875 0.5984 0.0 0
M  V30 20 C -3.9496 1.891 0.0 0
M  V30 21 C 7.5402 0.1316 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 6 3 CFG=1
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 5 9
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 7 12
M  V30 12 2 10 13
M  V30 13 1 11 14 CFG=3
M  V30 14 1 11 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 2 14 19
M  V30 19 1 14 20
M  V30 20 1 16 21
M  V30 21 1 7 9
M  V30 22 1 15 17
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 6 11)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000800A1-20220106-C00003

>  <Row No>
886

$$$$
US20220000800A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0358 -1.4582 0.0 0
M  V30 3 O 1.2192 -2.1754 0.0 0
M  V30 4 C -1.3626 -2.1754 0.0 0
M  V30 5 C -2.6894 -1.3985 0.0 0
M  V30 6 C -1.3985 -3.6337 0.0 0
M  V30 7 O -2.7253 0.1314 0.0 0
M  V30 8 C -4.0162 -2.1157 0.0 0
M  V30 9 C -2.7253 -4.3629 0.0 0
M  V30 10 C -0.1434 -4.3629 0.0 0
M  V30 11 C -4.0521 -3.574 0.0 0
M  V30 12 C -5.3431 -1.3507 0.0 0 CFG=2
M  V30 13 C 1.1116 -3.5979 0.0 0
M  V30 14 O -5.3789 -4.3031 0.0 0
M  V30 15 C -4.6139 -0.0239 0.0 0
M  V30 16 C -6.8731 -1.3148 0.0 0 CFG=2
M  V30 17 C 2.3667 -4.327 0.0 0
M  V30 18 C -5.3789 1.3029 0.0 0
M  V30 19 C -7.6381 -2.5699 0.0 0
M  V30 20 C -7.6381 0.0119 0.0 0
M  V30 21 C -6.9089 1.3387 0.0 0
M  V30 22 C -4.6498 2.6297 0.0 0
M  V30 23 C -6.9089 -3.825 0.0 0
M  V30 24 C -9.1681 -2.534 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 4 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 6 10
M  V30 10 2 8 11
M  V30 11 1 12 8 CFG=1
M  V30 12 1 10 13
M  V30 13 1 11 14
M  V30 14 1 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 2 15 18
M  V30 18 1 16 19 CFG=3
M  V30 19 1 16 20
M  V30 20 1 18 21
M  V30 21 1 18 22
M  V30 22 2 19 23
M  V30 23 1 19 24
M  V30 24 1 9 11
M  V30 25 1 20 21
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 12 16)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000800A1-20220106-C00004

>  <Row No>
887

$$$$
US20220000800A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 24 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2563 0.7657 0.0 0
M  V30 3 C -1.328 0.7657 0.0 0
M  V30 4 C 1.2204 2.2972 0.0 0
M  V30 5 C 2.5126 0.0358 0.0 0
M  V30 6 C -1.3639 2.2972 0.0 0 CFG=2
M  V30 7 C -2.8595 0.8016 0.0 0
M  V30 8 C -2.1058 -0.4905 0.0 0
M  V30 9 C 2.4767 3.0749 0.0 0
M  V30 10 C -0.1076 3.0749 0.0 0 CFG=2
M  V30 11 C 3.7689 0.8136 0.0 0
M  V30 12 C -2.692 3.0749 0.0 0
M  V30 13 C -2.692 1.5793 0.0 0
M  V30 14 O 2.4408 4.6064 0.0 0
M  V30 15 C 3.733 2.357 0.0 0
M  V30 16 C -0.1435 4.6064 0.0 0
M  V30 17 C 5.0252 0.0837 0.0 0
M  V30 18 C -2.7279 4.6064 0.0 0
M  V30 19 C -1.4716 5.3841 0.0 0
M  V30 20 C 6.2815 0.8614 0.0 0
M  V30 21 C -1.5075 6.9156 0.0 0
M  V30 22 C 7.5378 0.1316 0.0 0
M  V30 23 C 8.7941 0.9093 0.0 0
M  V30 24 C 10.0504 0.1794 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 3 8
M  V30 8 1 4 9
M  V30 9 1 4 10
M  V30 10 2 5 11
M  V30 11 1 6 12
M  V30 12 1 6 13 CFG=3
M  V30 13 1 9 14
M  V30 14 2 9 15
M  V30 15 1 10 16 CFG=3
M  V30 16 1 11 17
M  V30 17 1 12 18
M  V30 18 2 16 19
M  V30 19 1 17 20
M  V30 20 1 19 21
M  V30 21 1 20 22
M  V30 22 1 22 23
M  V30 23 1 23 24
M  V30 24 1 6 10
M  V30 25 1 11 15
M  V30 26 1 18 19
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 6 10)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00029001.cdx

>  <name>
US20220000800A1-20220106-C00005

>  <Row No>
888

$$$$
US20220000804A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4658 0.0 0
M  V30 3 C -1.3696 -2.1867 0.0 0
M  V30 4 C 1.2255 -2.1867 0.0 0
M  V30 5 C -2.7033 -1.3937 0.0 0
M  V30 6 C 2.487 -1.3937 0.0 0
M  V30 7 C -4.0369 -2.1146 0.0 0
M  V30 8 C 3.7486 -2.1146 0.0 0
M  V30 9 C -5.3706 -1.3216 0.0 0
M  V30 10 C -4.073 -3.5804 0.0 0
M  V30 11 C 5.0101 -1.3216 0.0 0
M  V30 12 C 3.7125 -3.5804 0.0 0
M  V30 13 O -5.4066 0.2162 0.0 0
M  V30 14 C -6.7042 -2.0425 0.0 0
M  V30 15 C -5.4066 -4.3013 0.0 0
M  V30 16 O 4.9741 0.2162 0.0 0
M  V30 17 C 6.2717 -2.0425 0.0 0
M  V30 18 C 4.9741 -4.3013 0.0 0
M  V30 19 C -6.7403 0.9972 0.0 0
M  V30 20 C -6.7403 -3.5083 0.0 0
M  V30 21 C 3.6405 0.9972 0.0 0
M  V30 22 C 6.2357 -3.5083 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 9 14
M  V30 14 2 10 15
M  V30 15 1 11 16
M  V30 16 1 11 17
M  V30 17 2 12 18
M  V30 18 1 13 19
M  V30 19 2 14 20
M  V30 20 1 16 21
M  V30 21 2 17 22
M  V30 22 1 15 20
M  V30 23 1 18 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000804A1-20220106-C00001

>  <Row No>
889

$$$$
US20220000804A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4658 0.0 0
M  V30 3 C 1.2255 -2.1867 0.0 0
M  V30 4 C -1.3696 -2.1867 0.0 0
M  V30 5 C 2.487 -1.3937 0.0 0
M  V30 6 C -2.7033 -1.3937 0.0 0
M  V30 7 C 3.7486 -2.1146 0.0 0
M  V30 8 C -4.0369 -2.1146 0.0 0
M  V30 9 C 5.0101 -1.3216 0.0 0
M  V30 10 C 3.7125 -3.5804 0.0 0
M  V30 11 C -5.3706 -1.3216 0.0 0
M  V30 12 C -4.073 -3.5804 0.0 0
M  V30 13 O 4.9741 0.2162 0.0 0
M  V30 14 C 6.2717 -2.0425 0.0 0
M  V30 15 C 4.9741 -4.3013 0.0 0
M  V30 16 O -5.4066 0.2162 0.0 0
M  V30 17 C -6.7042 -2.0425 0.0 0
M  V30 18 C -5.4066 -4.3013 0.0 0
M  V30 19 C 3.6405 0.9972 0.0 0
M  V30 20 C 6.2357 -3.5083 0.0 0
M  V30 21 C -6.7403 0.9972 0.0 0
M  V30 22 C -6.7403 -3.5083 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 9 14
M  V30 14 2 10 15
M  V30 15 1 11 16
M  V30 16 1 11 17
M  V30 17 2 12 18
M  V30 18 1 13 19
M  V30 19 2 14 20
M  V30 20 1 16 21
M  V30 21 2 17 22
M  V30 22 1 15 20
M  V30 23 1 18 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000804A1-20220106-C00002

>  <Row No>
890

$$$$
US20220000804A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4658 0.0 0
M  V30 3 C -1.3696 -2.1867 0.0 0
M  V30 4 C 1.2255 -2.1867 0.0 0
M  V30 5 C -2.7033 -1.3937 0.0 0
M  V30 6 C 2.487 -1.3937 0.0 0
M  V30 7 C -4.0369 -2.1146 0.0 0
M  V30 8 C 3.7486 -2.1146 0.0 0
M  V30 9 C -5.3706 -1.3216 0.0 0
M  V30 10 C -4.073 -3.5804 0.0 0
M  V30 11 C 5.0101 -1.3216 0.0 0
M  V30 12 C 3.7125 -3.5804 0.0 0
M  V30 13 O -5.4066 0.2162 0.0 0
M  V30 14 C -6.7042 -2.0425 0.0 0
M  V30 15 C -5.4066 -4.3013 0.0 0
M  V30 16 O 4.9741 0.2162 0.0 0
M  V30 17 C 6.2717 -2.0425 0.0 0
M  V30 18 C 4.9741 -4.3013 0.0 0
M  V30 19 C -6.7403 0.9972 0.0 0
M  V30 20 C -6.7403 -3.5083 0.0 0
M  V30 21 C 3.6405 0.9972 0.0 0
M  V30 22 C 6.2357 -3.5083 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 9 14
M  V30 14 2 10 15
M  V30 15 1 11 16
M  V30 16 1 11 17
M  V30 17 2 12 18
M  V30 18 1 13 19
M  V30 19 2 14 20
M  V30 20 1 16 21
M  V30 21 2 17 22
M  V30 22 1 15 20
M  V30 23 1 18 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000804A1-20220106-C00003

>  <Row No>
891

$$$$
US20220000804A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.036 -1.4658 0.0 0
M  V30 3 C -1.3696 -2.1867 0.0 0
M  V30 4 C 1.2255 -2.1867 0.0 0
M  V30 5 C -2.7033 -1.3937 0.0 0
M  V30 6 C 2.487 -1.3937 0.0 0
M  V30 7 C -4.0369 -2.1146 0.0 0
M  V30 8 C 3.7486 -2.1146 0.0 0
M  V30 9 C -5.3706 -1.3216 0.0 0
M  V30 10 C -4.073 -3.5804 0.0 0
M  V30 11 C 5.0101 -1.3216 0.0 0
M  V30 12 C 3.7125 -3.5804 0.0 0
M  V30 13 O -5.4066 0.2162 0.0 0
M  V30 14 C -6.7042 -2.0425 0.0 0
M  V30 15 C -5.4066 -4.3013 0.0 0
M  V30 16 O 4.9741 0.2162 0.0 0
M  V30 17 C 6.2717 -2.0425 0.0 0
M  V30 18 C 4.9741 -4.3013 0.0 0
M  V30 19 C -6.7403 0.9972 0.0 0
M  V30 20 C -6.7403 -3.5083 0.0 0
M  V30 21 C 3.6405 0.9972 0.0 0
M  V30 22 C 6.2357 -3.5083 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 2 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 8 2 7 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 9 14
M  V30 14 2 10 15
M  V30 15 1 11 16
M  V30 16 1 11 17
M  V30 17 2 12 18
M  V30 18 1 13 19
M  V30 19 2 14 20
M  V30 20 1 16 21
M  V30 21 2 17 22
M  V30 22 1 15 20
M  V30 23 1 18 22
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000804A1-20220106-C00004

>  <Row No>
892

$$$$
US20220000805A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 34 40 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.8696 1.5786 0.0 0
M  V30 3 C 0.8696 -1.4181 0.0 0 CFG=2
M  V30 4 C 0.8294 3.1172 0.0 0
M  V30 5 C 2.1272 0.8829 0.0 0
M  V30 6 C 0.8294 -2.8764 0.0 0 CFG=2
M  V30 7 C 2.1272 -0.6421 0.0 0 CFG=1
M  V30 8 O -0.5083 3.8931 0.0 0
M  V30 9 C 2.087 3.8931 0.0 0
M  V30 10 C 3.3847 1.6589 0.0 0
M  V30 11 O -0.5083 -3.572 0.0 0
M  V30 12 C 2.087 -3.572 0.0 0 CFG=2
M  V30 13 C 1.5251 -1.5385 0.0 0
M  V30 14 C 3.3847 -1.3378 0.0 0 CFG=2
M  V30 15 C 3.3847 0.1337 0.0 0
M  V30 16 C 3.3446 3.1974 0.0 0
M  V30 17 C 4.6423 0.9632 0.0 0
M  V30 18 C -1.8462 -2.7961 0.0 0
M  V30 19 C 2.7827 -4.8296 0.0 0 CFG=1
M  V30 20 C 3.3446 -2.7961 0.0 0
M  V30 21 C 2.582 -2.5954 0.0 0
M  V30 22 C 4.6423 -0.5619 0.0 0
M  V30 23 C 5.0705 0.1739 0.0 0
M  V30 24 O 4.0403 -4.0537 0.0 0
M  V30 25 C 2.0067 -6.0872 0.0 0
M  V30 26 C 4.0403 -5.5253 0.0 0
M  V30 27 N 5.8999 -1.2575 0.0 0
M  V30 28 C 0.4682 -6.0471 0.0 0
M  V30 29 C 1.9666 -7.5455 0.0 0
M  V30 30 C 3.2643 -6.7829 0.0 0
M  V30 31 C 5.8598 -2.7158 0.0 0
M  V30 32 C 7.1174 -3.4115 0.0 0
M  V30 33 C 7.8131 -4.6691 0.0 0
M  V30 34 C 8.5757 -3.3714 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 3 1 CFG=1
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 4 9
M  V30 9 2 5 10
M  V30 10 1 6 11 CFG=3
M  V30 11 1 6 12
M  V30 12 1 6 13
M  V30 13 1 7 14
M  V30 14 1 7 15 CFG=3
M  V30 15 2 9 16
M  V30 16 1 10 17
M  V30 17 1 11 18
M  V30 18 1 12 19
M  V30 19 1 12 20 CFG=1
M  V30 20 1 13 21
M  V30 21 1 14 22
M  V30 22 1 15 23
M  V30 23 1 19 24 CFG=1
M  V30 24 1 19 25
M  V30 25 1 19 26
M  V30 26 1 22 27
M  V30 27 1 25 28
M  V30 28 1 25 29
M  V30 29 1 25 30
M  V30 30 1 27 31
M  V30 31 1 31 32
M  V30 32 1 32 33
M  V30 33 1 32 34
M  V30 34 1 5 7
M  V30 35 1 10 16
M  V30 36 1 14 20 CFG=3
M  V30 37 1 14 21
M  V30 38 1 17 22
M  V30 39 1 23 27
M  V30 40 1 33 34
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(6 3 6 7 12 14 19)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000805A1-20220106-C00001

>  <Row No>
893

$$$$
US20220000805A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 16 17 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.4787 0.0352 0.0 0
M  V30 3 C 2.1829 -1.244 0.0 0
M  V30 4 C 2.1829 1.3848 0.0 0
M  V30 5 C 3.6616 -1.2088 0.0 0
M  V30 6 C 1.3848 -2.5232 0.0 0 CFG=1
M  V30 7 C 3.6616 1.42 0.0 0
M  V30 8 C 4.401 0.1408 0.0 0
M  V30 9 N 2.8636 -2.488 0.0 0
M  V30 10 C 1.3496 -4.002 0.0 0
M  V30 11 C 0.0352 -1.7252 0.0 0
M  V30 12 C 3.5677 -3.7673 0.0 0
M  V30 13 O 2.6288 -4.7179 0.0 0
M  V30 14 C 0.0 -4.7179 0.0 0
M  V30 15 C -1.3144 -2.4293 0.0 0
M  V30 16 C -1.3496 -3.9081 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 6 9 CFG=3
M  V30 9 1 6 10
M  V30 10 1 6 11
M  V30 11 1 9 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 1 11 15
M  V30 15 1 14 16
M  V30 16 1 7 8
M  V30 17 1 15 16
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 6)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000805A1-20220106-C00002

>  <Row No>
894

$$$$
US20220000805A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 31 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.4562 -0.4058 0.0 0
M  V30 3 C -2.5782 0.6326 0.0 0
M  V30 4 C -1.8262 -1.8262 0.0 0
M  V30 5 C -4.0344 0.2267 0.0 0
M  V30 6 C -3.2824 -2.232 0.0 0
M  V30 7 S -4.9893 1.4204 0.0 0
M  V30 8 C -4.4045 -1.1936 0.0 0
M  V30 9 O -5.0252 2.9482 0.0 0
M  V30 10 O -3.9748 2.5066 0.0 0
M  V30 11 N -6.5172 1.4562 0.0 0
M  V30 12 C -5.7771 -1.8143 0.0 0 CFG=1
M  V30 13 C -7.4721 0.3342 0.0 0
M  V30 14 C -7.2811 2.7811 0.0 0
M  V30 15 N -5.813 -3.2705 0.0 0
M  V30 16 C -7.1498 -1.122 0.0 0
M  V30 17 C -8.9283 0.8116 0.0 0
M  V30 18 C -7.1379 -3.9867 0.0 0
M  V30 19 C -8.2718 -2.0888 0.0 0
M  V30 20 C -10.0504 -0.1551 0.0 0
M  V30 21 C -7.1737 -5.4429 0.0 0
M  V30 22 C -9.7281 -1.6114 0.0 0
M  V30 23 C -8.4986 -6.1591 0.0 0
M  V30 24 C -8.5344 -7.6153 0.0 0
M  V30 25 C -9.8594 -8.3315 0.0 0
M  V30 26 C -9.8952 -9.7878 0.0 0
M  V30 27 C -11.2201 -10.5039 0.0 0
M  V30 28 O -12.545 -9.7281 0.0 0
M  V30 29 O -11.2559 -11.9602 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 2 7 9
M  V30 9 2 7 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 11 13
M  V30 13 1 11 14
M  V30 14 1 12 15 CFG=1
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 2 17 20
M  V30 20 1 18 21
M  V30 21 2 19 22
M  V30 22 1 21 23
M  V30 23 1 23 24
M  V30 24 1 24 25
M  V30 25 1 25 26
M  V30 26 1 26 27
M  V30 27 2 27 28
M  V30 28 1 27 29
M  V30 29 1 6 8
M  V30 30 2 13 16
M  V30 31 1 20 22
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 12)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000805A1-20220106-C00003

>  <Row No>
895

$$$$
US20220000805A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 18 20 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.5085 0.0364 0.0 0
M  V30 3 C 2.2263 -1.2652 0.0 0
M  V30 4 C 2.2263 1.4112 0.0 0
M  V30 5 C 3.7349 -1.2287 0.0 0
M  V30 6 C 3.7349 1.4477 0.0 0
M  V30 7 C 4.4527 0.1459 0.0 0
M  V30 8 C 4.4527 -2.5305 0.0 0 CFG=2
M  V30 9 C 5.9612 0.1824 0.0 0
M  V30 10 C 5.9612 -2.494 0.0 0 CFG=2
M  V30 11 C 4.6838 -4.0634 0.0 0
M  V30 12 C 2.9319 -2.8833 0.0 0
M  V30 13 C 6.679 -1.1192 0.0 0 CFG=1
M  V30 14 N 6.5574 -3.674 0.0 0
M  V30 15 C 5.9856 -4.9271 0.0 0
M  V30 16 C 7.8104 -1.764 0.0 0
M  V30 17 C 7.4333 -4.623 0.0 0
M  V30 18 C 8.1633 -3.2117 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 1 8 10
M  V30 10 1 8 11
M  V30 11 1 8 12 CFG=1
M  V30 12 1 9 13
M  V30 13 1 10 14 CFG=3
M  V30 14 1 11 15
M  V30 15 1 13 16 CFG=3
M  V30 16 1 15 17
M  V30 17 1 16 18
M  V30 18 1 6 7
M  V30 19 1 10 13
M  V30 20 1 17 18
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 8 10 13)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000805A1-20220106-C00004

>  <Row No>
896

$$$$
US20220000805A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 25 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.8646 1.5811 0.0 0
M  V30 3 C 0.8646 -1.4205 0.0 0 CFG=2
M  V30 4 C 0.8276 3.1129 0.0 0
M  V30 5 C 2.1246 0.8523 0.0 0
M  V30 6 C 2.1246 -0.6176 0.0 0 CFG=2
M  V30 7 C 0.8276 -2.8782 0.0 0 CFG=1
M  V30 8 O -0.5064 3.9034 0.0 0
M  V30 9 C 2.0876 3.9034 0.0 0
M  V30 10 C 3.3846 1.6552 0.0 0
M  V30 11 C 3.3846 -1.3464 0.0 0 CFG=1
M  V30 12 C 2.8534 -1.8776 0.0 0
M  V30 13 O -0.5064 -3.607 0.0 0
M  V30 14 C 2.0876 -3.607 0.0 0
M  V30 15 C 3.3476 3.1746 0.0 0
M  V30 16 C 4.6446 0.9264 0.0 0
M  V30 17 C 3.3476 -2.804 0.0 0
M  V30 18 C 4.6446 -0.5435 0.0 0 CFG=1
M  V30 19 C 4.1134 -2.6064 0.0 0
M  V30 20 N 5.3734 -1.8035 0.0 0
M  V30 21 C 6.7816 -2.1617 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 3 1 CFG=3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 4 8
M  V30 8 1 4 9
M  V30 9 2 5 10
M  V30 10 1 6 11
M  V30 11 1 6 12 CFG=1
M  V30 12 1 7 13 CFG=3
M  V30 13 1 7 14
M  V30 14 2 9 15
M  V30 15 1 10 16
M  V30 16 1 11 17 CFG=3
M  V30 17 1 11 18
M  V30 18 1 12 19
M  V30 19 1 18 20 CFG=1
M  V30 20 1 20 21
M  V30 21 1 5 6
M  V30 22 1 10 15
M  V30 23 2 14 17
M  V30 24 1 16 18
M  V30 25 1 19 20
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(5 3 6 7 11 18)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000805A1-20220106-C00005

>  <Row No>
897

$$$$
US20220000805A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 26 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C -0.0359 -1.4625 0.0 0
M  V30 3 O -1.3666 -2.1817 0.0 0
M  V30 4 C 1.2227 -2.1817 0.0 0
M  V30 5 C -2.1458 -3.4405 0.0 0 CFG=2
M  V30 6 C 2.4814 -1.4025 0.0 0
M  V30 7 C -3.4764 -4.1597 0.0 0
M  V30 8 C -0.8871 -4.1717 0.0 0 CFG=1
M  V30 9 C -2.925 -2.1098 0.0 0
M  V30 10 C -4.8071 -3.3805 0.0 0
M  V30 11 C -3.5124 -5.6223 0.0 0
M  V30 12 C 0.3836 -3.3925 0.0 0
M  V30 13 C -0.923 -5.6342 0.0 0
M  V30 14 C -4.2556 -1.3306 0.0 0
M  V30 15 C -6.1377 -4.0998 0.0 0
M  V30 16 C -4.843 -6.3415 0.0 0
M  V30 17 N 1.6543 -4.0998 0.0 0
M  V30 18 C -5.5863 -2.0499 0.0 0
M  V30 19 C -4.2916 0.2037 0.0 0
M  V30 20 C -6.1737 -5.5623 0.0 0
M  V30 21 C 2.901 -3.3086 0.0 0
M  V30 22 C 1.6183 -5.5623 0.0 0
M  V30 23 C -6.9169 -1.2707 0.0 0
M  V30 24 C -5.6223 0.983 0.0 0
M  V30 25 C -6.9529 0.2637 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 5 3 CFG=1
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 2 7 10
M  V30 10 1 7 11
M  V30 11 1 8 12
M  V30 12 1 8 13 CFG=1
M  V30 13 1 9 14
M  V30 14 1 10 15
M  V30 15 2 11 16
M  V30 16 1 12 17
M  V30 17 2 14 18
M  V30 18 1 14 19
M  V30 19 2 15 20
M  V30 20 1 17 21
M  V30 21 1 17 22
M  V30 22 1 18 23
M  V30 23 2 19 24
M  V30 24 2 23 25
M  V30 25 1 16 20
M  V30 26 1 24 25
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(2 5 8)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000805A1-20220106-C00006

>  <Row No>
898

$$$$
US20220000805A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 23 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2451 0.7812 0.0 0
M  V30 3 C 1.2085 2.295 0.0 0 CFG=1
M  V30 4 C 2.4903 0.061 0.0 0
M  V30 5 O 0.2807 3.7721 0.0 0
M  V30 6 C 2.4537 3.0763 0.0 0 CFG=1
M  V30 7 C 3.7355 0.8423 0.0 0
M  V30 8 C 1.1353 5.3347 0.0 0
M  V30 9 C 2.4171 4.59 0.0 0
M  V30 10 C 3.6989 2.356 0.0 0 CFG=1
M  V30 11 C 3.1739 1.8311 0.0 0
M  V30 12 C 1.0986 6.8484 0.0 0
M  V30 13 C 3.6622 5.3713 0.0 0
M  V30 14 O 3.6622 3.8698 0.0 0
M  V30 15 C 4.944 3.1373 0.0 0 CFG=2
M  V30 16 C 4.4191 1.1108 0.0 0
M  V30 17 O -0.2197 7.6419 0.0 0
M  V30 18 C 2.3438 7.6419 0.0 0
M  V30 19 C 3.6256 6.885 0.0 0
M  V30 20 C 4.9074 4.651 0.0 0
M  V30 21 N 5.6643 1.8921 0.0 0
M  V30 22 C -1.5381 6.9217 0.0 0
M  V30 23 C 7.0559 1.5381 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5 CFG=1
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 6 10
M  V30 10 1 6 11 CFG=3
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 10 14 CFG=3
M  V30 14 1 10 15
M  V30 15 1 11 16
M  V30 16 1 12 17
M  V30 17 2 12 18
M  V30 18 2 13 19
M  V30 19 1 13 20
M  V30 20 1 15 21 CFG=3
M  V30 21 1 17 22
M  V30 22 1 21 23
M  V30 23 1 7 10
M  V30 24 2 8 9
M  V30 25 1 15 20
M  V30 26 1 16 21
M  V30 27 1 18 19
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(4 3 6 10 15)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000805A1-20220106-C00007

>  <Row No>
899

$$$$
US20220000805A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 29 32 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.7813 -1.2452 0.0 0
M  V30 3 O 2.2707 -1.1231 0.0 0
M  V30 4 C 0.0366 -2.5637 0.0 0
M  V30 5 C 3.0521 -2.3684 0.0 0
M  V30 6 C -1.526 -2.6126 0.0 0
M  V30 7 C 0.8179 -3.809 0.0 0 CFG=2
M  V30 8 O -2.2707 -3.9311 0.0 0
M  V30 9 C 0.0732 -5.1275 0.0 0 CFG=1
M  V30 10 C 2.3073 -3.6869 0.0 0
M  V30 11 C -3.8334 -3.9799 0.0 0
M  V30 12 C 0.8545 -6.3728 0.0 0
M  V30 13 C -1.4894 -5.1763 0.0 0
M  V30 14 C 3.0887 -4.9322 0.0 0 CFG=2
M  V30 15 N 2.344 -6.2507 0.0 0
M  V30 16 C -2.2341 -6.4949 0.0 0
M  V30 17 C 4.5781 -4.8101 0.0 0
M  V30 18 C 3.1253 -7.4959 0.0 0
M  V30 19 N 5.4938 -3.5892 0.0 0
M  V30 20 C 5.3595 -6.0553 0.0 0
M  V30 21 C 4.6147 -7.3739 0.0 0
M  V30 22 C 6.8855 -4.1142 0.0 0
M  V30 23 C 6.8001 -5.6158 0.0 0
M  V30 24 C 8.204 -3.3695 0.0 0
M  V30 25 C 8.0453 -6.3972 0.0 0
M  V30 26 C 9.4493 -4.1508 0.0 0
M  V30 27 O 7.9232 -7.8866 0.0 0
M  V30 28 C 9.3638 -5.6525 0.0 0
M  V30 29 C 9.1685 -8.668 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 7 4 CFG=1
M  V30 7 1 6 8
M  V30 8 1 7 9
M  V30 9 1 7 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 1 9 13 CFG=1
M  V30 13 1 10 14
M  V30 14 1 12 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 1 15 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 1 18 21
M  V30 21 1 19 22
M  V30 22 1 20 23
M  V30 23 1 22 24
M  V30 24 1 23 25
M  V30 25 2 24 26
M  V30 26 1 25 27
M  V30 27 2 25 28
M  V30 28 1 27 29
M  V30 29 1 14 15 CFG=1
M  V30 30 1 20 21
M  V30 31 2 22 23
M  V30 32 1 26 28
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 7 9 14)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000805A1-20220106-C00008

>  <Row No>
900

$$$$
US20220000808A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 4 3 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C 1.2932 -0.7389 0.0 0
M  V30 3 C 2.5864 0.0615 0.0 0
M  V30 4 C 3.8797 -0.6774 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000808A1-20220106-C00001

>  <Row No>
901

$$$$
US20220000808A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 7 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 S 1.2778 -0.7122 0.0 0
M  V30 3 C -1.3407 -0.7122 0.0 0
M  V30 4 C 2.5557 0.0628 0.0 0
M  V30 5 C -2.6814 0.0628 0.0 0
M  V30 6 C 3.8335 -0.6494 0.0 0
M  V30 7 N -4.0221 -0.6494 0.0 0
M  V30 8 C 5.1114 0.1256 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 1 5 7
M  V30 7 1 6 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000808A1-20220106-C00002

>  <Row No>
902

$$$$
US20220000808A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 7 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 P 1.2638 0.7666 0.0 0 CFG=2
M  V30 3 C -1.326 0.7666 0.0 0
M  V30 4 O 0.4972 2.0926 0.0 0
M  V30 5 O 1.9683 -0.4972 0.0 0
M  V30 6 C 2.5277 1.5332 0.0 0
M  V30 7 C -2.652 0.0621 0.0 0
M  V30 8 N -3.9781 0.8287 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5 CFG=3
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 7 8
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(1 2)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000808A1-20220106-C00003

>  <Row No>
903

$$$$
US20220000808A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 4 3 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 C -1.3071 0.7557 0.0 0
M  V30 3 C -2.6143 0.0612 0.0 0
M  V30 4 N -3.9215 0.8169 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 2 3
M  V30 3 1 3 4
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000808A1-20220106-C00004

>  <Row No>
904

$$$$
US20220000808A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 8 7 0 0 0
M  V30 BEGIN ATOM
M  V30 1 S 0.0 0.0 0.0 0
M  V30 2 P 1.2638 0.7666 0.0 0
M  V30 3 C -1.326 0.7666 0.0 0
M  V30 4 O 0.4972 2.0926 0.0 0
M  V30 5 O 2.5277 1.5332 0.0 0
M  V30 6 O 1.9683 -0.4972 0.0 0
M  V30 7 C -2.652 0.0621 0.0 0
M  V30 8 N -3.9781 0.8287 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 2 2 4
M  V30 4 1 2 5
M  V30 5 1 2 6
M  V30 6 1 3 7
M  V30 7 1 7 8
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000808A1-20220106-C00005

>  <Row No>
905

$$$$
US20220000810A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 9 8 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C -0.0359 1.5347 0.0 0
M  V30 3 N -1.3668 2.314 0.0 0
M  V30 4 C 1.2229 2.314 0.0 0
M  V30 5 C -2.6977 1.5946 0.0 0
M  V30 6 C -1.4028 3.8487 0.0 0
M  V30 7 C 2.4819 1.5946 0.0 0
M  V30 8 N 2.4459 0.1318 0.0 0
M  V30 9 N 3.7408 2.374 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 7 8
M  V30 8 1 7 9
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000810A1-20220106-C00001

>  <Row No>
906

$$$$
US20220000810A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 15 15 0 0 0
M  V30 BEGIN ATOM
M  V30 1 N 0.0 0.0 0.0 0
M  V30 2 C -0.0356 -1.4509 0.0 0
M  V30 3 N 1.2131 -2.1645 0.0 0
M  V30 4 N -1.3558 -2.1645 0.0 0
M  V30 5 C 2.4619 -1.3796 0.0 0
M  V30 6 C -2.676 -1.3796 0.0 0
M  V30 7 N 2.4262 0.1427 0.0 0
M  V30 8 N 3.7107 -2.0932 0.0 0
M  V30 9 C -3.9961 -2.0932 0.0 0
M  V30 10 C -5.3163 -1.3201 0.0 0
M  V30 11 C -6.6364 -2.0337 0.0 0
M  V30 12 C -5.352 0.2021 0.0 0
M  V30 13 C -7.9566 -1.2488 0.0 0
M  V30 14 C -6.6721 0.9752 0.0 0
M  V30 15 C -7.9923 0.2735 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 1 9 10
M  V30 10 2 10 11
M  V30 11 1 10 12
M  V30 12 1 11 13
M  V30 13 2 12 14
M  V30 14 2 13 15
M  V30 15 1 14 15
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000810A1-20220106-C00002

>  <Row No>
907

$$$$
US20220000810A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 11 11 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 0.7194 -1.259 0.0 0 CFG=1
M  V30 3 C -1.4868 -0.3477 0.0 0
M  V30 4 O 0.6834 -2.7219 0.0 0
M  V30 5 C -0.7554 -0.8393 0.0 0
M  V30 6 C -2.9617 0.0719 0.0 0 CFG=1
M  V30 7 C -2.578 0.7434 0.0 0
M  V30 8 C -2.2422 -1.187 0.0 0 CFG=1
M  V30 9 O -4.2926 -0.3357 0.0 0
M  V30 10 O -2.6139 2.2782 0.0 0
M  V30 11 O -3.777 -1.0072 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 1 1 3
M  V30 3 1 2 4 CFG=1
M  V30 4 1 2 5
M  V30 5 1 3 6
M  V30 6 1 3 7
M  V30 7 1 5 8
M  V30 8 1 6 9 CFG=1
M  V30 9 1 7 10
M  V30 10 1 8 11 CFG=3
M  V30 11 1 6 8
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(3 2 6 8)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00023001.cdx

>  <name>
US20220000810A1-20220106-C00003

>  <Row No>
908

$$$$
US20220000810A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 28 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 P 0.0 0.0 0.0 0
M  V30 2 O -1.3351 0.7698 0.0 0
M  V30 3 O -0.036 -1.4675 0.0 0
M  V30 4 O 1.263 -0.7337 0.0 0
M  V30 5 O 1.263 0.7698 0.0 0
M  V30 6 C -1.3712 -2.1892 0.0 0 CFG=2
M  V30 7 C -1.4073 -3.6567 0.0 0 CFG=1
M  V30 8 C -2.7064 -1.4193 0.0 0 CFG=1
M  V30 9 O -0.1443 -4.3784 0.0 0
M  V30 10 C -2.7425 -4.3784 0.0 0 CFG=2
M  V30 11 O -2.7425 0.1202 0.0 0
M  V30 12 C -4.0416 -2.1411 0.0 0 CFG=2
M  V30 13 P 1.1186 -3.6086 0.0 0
M  V30 14 O -2.7786 -5.8459 0.0 0
M  V30 15 C -4.0777 -3.6086 0.0 0 CFG=2
M  V30 16 P -4.0777 0.9021 0.0 0
M  V30 17 C -5.3768 -1.3712 0.0 0
M  V30 18 O 1.0825 -2.0689 0.0 0
M  V30 19 O 1.0825 -5.0761 0.0 0
M  V30 20 O 2.3816 -4.3303 0.0 0
M  V30 21 P -1.5156 -6.5797 0.0 0
M  V30 22 C -5.4129 -4.3303 0.0 0
M  V30 23 O -5.4129 0.1684 0.0 0
M  V30 24 O -2.8147 1.672 0.0 0
M  V30 25 O -4.1138 2.4418 0.0 0
M  V30 26 O -0.2526 -5.8098 0.0 0
M  V30 27 O -2.8508 -7.3014 0.0 0
M  V30 28 O -1.5517 -8.0472 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 2 1 2
M  V30 2 1 1 3
M  V30 3 1 1 4
M  V30 4 1 1 5
M  V30 5 1 6 3 CFG=3
M  V30 6 1 6 7
M  V30 7 1 6 8
M  V30 8 1 7 9 CFG=1
M  V30 9 1 7 10
M  V30 10 1 8 11 CFG=3
M  V30 11 1 8 12
M  V30 12 1 9 13
M  V30 13 1 10 14 CFG=3
M  V30 14 1 10 15
M  V30 15 1 11 16
M  V30 16 1 12 17 CFG=3
M  V30 17 2 13 18
M  V30 18 1 13 19
M  V30 19 1 13 20
M  V30 20 1 14 21
M  V30 21 1 15 22 CFG=1
M  V30 22 2 16 23
M  V30 23 1 16 24
M  V30 24 1 16 25
M  V30 25 2 21 26
M  V30 26 1 21 27
M  V30 27 1 21 28
M  V30 28 1 12 15
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STERAC1 ATOMS=(6 6 7 8 10 12 15)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000810A1-20220106-C00004

>  <Row No>
909

$$$$
US20220000810A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 12 12 0 0 0
M  V30 BEGIN ATOM
M  V30 1 O 0.0 0.0 0.0 0
M  V30 2 C 1.2831 -0.7332 0.0 0 CFG=1
M  V30 3 C 1.2464 -2.224 0.0 0 CFG=2
M  V30 4 C 2.5662 0.0488 0.0 0 CFG=2
M  V30 5 O -0.1099 -2.9573 0.0 0
M  V30 6 C 2.5295 -2.9573 0.0 0 CFG=1
M  V30 7 O 2.5295 1.613 0.0 0
M  V30 8 C 3.8493 -0.6843 0.0 0 CFG=1
M  V30 9 O 2.4929 -4.4481 0.0 0
M  V30 10 C 3.8127 -2.1752 0.0 0 CFG=1
M  V30 11 O 5.1325 0.0977 0.0 0
M  V30 12 O 5.0958 -2.9084 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 2 1 CFG=3
M  V30 2 1 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5 CFG=1
M  V30 5 1 3 6
M  V30 6 1 4 7 CFG=3
M  V30 7 1 4 8
M  V30 8 1 6 9 CFG=3
M  V30 9 1 6 10
M  V30 10 1 8 11 CFG=3
M  V30 11 1 10 12 CFG=1
M  V30 12 1 8 10
M  V30 END BOND
M  V30 BEGIN COLLECTION
M  V30 MDLV30/STEABS ATOMS=(6 2 3 4 6 8 10)
M  V30 END COLLECTION
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000810A1-20220106-C00005

>  <Row No>
910

$$$$
US20220000811A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000811A1-20220106-C00001

>  <Row No>
911

$$$$
US20220000811A1-20220106-C00002
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 47 47 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3256 0.8006 0.0 0
M  V30 3 C -1.365 2.3362 0.0 0
M  V30 4 C -2.6512 0.0787 0.0 0
M  V30 5 Cl -0.1181 3.1369 0.0 0
M  V30 6 C -2.6906 3.1369 0.0 0
M  V30 7 C -3.9769 0.8793 0.0 0
M  V30 8 C -4.0163 2.415 0.0 0
M  V30 9 C -5.3025 0.1575 0.0 0
M  V30 10 C -6.6282 0.9581 0.0 0
M  V30 11 N -7.9538 0.2362 0.0 0
M  V30 12 C -9.2795 1.0368 0.0 0
M  V30 13 N -9.3189 2.5725 0.0 0
M  V30 14 N -10.6051 0.315 0.0 0
M  V30 15 C -11.9308 1.1156 0.0 0
M  V30 16 N -11.9702 2.6512 0.0 0
M  V30 17 N -13.2564 0.3937 0.0 0
M  V30 18 N -11.3402 11.4452 0.0 0
M  V30 19 C -11.3795 9.9883 0.0 0
M  V30 20 N -12.7052 9.2664 0.0 0
M  V30 21 N -10.1326 9.2664 0.0 0
M  V30 22 C -14.0308 10.067 0.0 0
M  V30 23 C -8.8857 10.067 0.0 0
M  V30 24 N -14.0702 11.6027 0.0 0
M  V30 25 N -15.3565 9.3451 0.0 0
M  V30 26 C -7.6388 9.3451 0.0 0
M  V30 27 C -6.3919 10.1458 0.0 0
M  V30 28 C -6.4313 11.6814 0.0 0
M  V30 29 C -5.145 9.4239 0.0 0
M  V30 30 C -5.1844 12.482 0.0 0
M  V30 31 C -7.757 12.482 0.0 0
M  V30 32 C -3.8981 10.2245 0.0 0
M  V30 33 C -3.9375 11.7602 0.0 0
M  V30 34 N -13.4402 -3.57 0.0 0
M  V30 35 C -13.4796 -5.0269 0.0 0
M  V30 36 N -12.2327 -5.7488 0.0 0
M  V30 37 N -14.8052 -5.7488 0.0 0
M  V30 38 C -10.9858 -4.9482 0.0 0
M  V30 39 C -9.7389 -5.6701 0.0 0
M  V30 40 C -8.492 -4.8694 0.0 0
M  V30 41 C -7.2451 -5.5913 0.0 0
M  V30 42 C -8.5314 -3.3338 0.0 0
M  V30 43 C -5.9982 -4.7907 0.0 0
M  V30 44 C -7.2845 -2.5331 0.0 0
M  V30 45 C -6.0376 -3.255 0.0 0
M  V30 46 C -4.7513 -5.5125 0.0 0
M  V30 47 C -4.7907 -2.4544 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 2 18 19
M  V30 18 1 19 20
M  V30 19 1 19 21
M  V30 20 1 20 22
M  V30 21 1 21 23
M  V30 22 2 22 24
M  V30 23 1 22 25
M  V30 24 1 23 26
M  V30 25 1 26 27
M  V30 26 2 27 28
M  V30 27 1 27 29
M  V30 28 1 28 30
M  V30 29 1 28 31
M  V30 30 2 29 32
M  V30 31 2 30 33
M  V30 32 2 34 35
M  V30 33 1 35 36
M  V30 34 1 35 37
M  V30 35 1 36 38
M  V30 36 1 38 39
M  V30 37 1 39 40
M  V30 38 2 40 41
M  V30 39 1 40 42
M  V30 40 1 41 43
M  V30 41 2 42 44
M  V30 42 2 43 45
M  V30 43 1 43 46
M  V30 44 1 45 47
M  V30 45 1 7 8
M  V30 46 1 32 33
M  V30 47 1 44 45
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00022001.cdx

>  <name>
US20220000811A1-20220106-C00002

>  <Row No>
912

$$$$
US20220000811A1-20220106-C00003
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=2
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000811A1-20220106-C00003

>  <Row No>
913

$$$$
US20220000811A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 47 47 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.3283 0.8022 0.0 0
M  V30 3 C -1.3678 2.3279 0.0 0
M  V30 4 C -2.6567 0.0789 0.0 0
M  V30 5 Cl -0.1183 3.1302 0.0 0
M  V30 6 C -2.6961 3.1302 0.0 0
M  V30 7 C -3.9851 0.8811 0.0 0
M  V30 8 C -4.0245 2.4068 0.0 0
M  V30 9 C -5.3134 0.1578 0.0 0
M  V30 10 C -6.6418 0.9601 0.0 0
M  V30 11 N -7.9702 0.2367 0.0 0
M  V30 12 C -9.2985 1.039 0.0 0
M  V30 13 N -9.338 2.5646 0.0 0
M  V30 14 N -10.6269 0.3156 0.0 0
M  V30 15 C -11.9553 1.1179 0.0 0
M  V30 16 N -11.9947 2.6435 0.0 0
M  V30 17 N -13.2836 0.3945 0.0 0
M  V30 18 N -11.3634 10.5217 0.0 0
M  V30 19 C -11.4029 9.0749 0.0 0
M  V30 20 N -12.7312 8.3516 0.0 0
M  V30 21 N -10.1534 8.3516 0.0 0
M  V30 22 C -14.0596 9.1539 0.0 0
M  V30 23 C -8.904 9.1539 0.0 0
M  V30 24 N -14.0991 10.6795 0.0 0
M  V30 25 N -15.388 8.4305 0.0 0
M  V30 26 C -7.6545 8.4305 0.0 0
M  V30 27 C -6.4051 9.2328 0.0 0
M  V30 28 C -6.4445 10.7584 0.0 0
M  V30 29 C -5.1556 8.5094 0.0 0
M  V30 30 C -5.1951 11.5607 0.0 0
M  V30 31 C -7.7729 11.5607 0.0 0
M  V30 32 C -3.9061 9.3117 0.0 0
M  V30 33 C -3.9456 10.8373 0.0 0
M  V30 34 N -13.4678 -7.8912 0.0 0
M  V30 35 C -13.5072 -9.338 0.0 0
M  V30 36 N -12.2578 -10.0614 0.0 0
M  V30 37 N -14.8356 -10.0614 0.0 0
M  V30 38 C -11.0083 -9.2591 0.0 0
M  V30 39 C -9.7589 -9.9824 0.0 0
M  V30 40 C -8.5094 -9.1802 0.0 0
M  V30 41 C -7.2599 -9.9035 0.0 0
M  V30 42 C -8.5489 -7.6545 0.0 0
M  V30 43 C -6.0105 -9.1012 0.0 0
M  V30 44 C -7.2994 -6.8522 0.0 0
M  V30 45 C -6.0499 -7.5756 0.0 0
M  V30 46 C -4.761 -9.8246 0.0 0
M  V30 47 C -4.8005 -6.7733 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 1 9 10
M  V30 10 1 10 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 14 15
M  V30 15 2 15 16
M  V30 16 1 15 17
M  V30 17 2 18 19
M  V30 18 1 19 20
M  V30 19 1 19 21
M  V30 20 1 20 22
M  V30 21 1 21 23
M  V30 22 2 22 24
M  V30 23 1 22 25
M  V30 24 1 23 26
M  V30 25 1 26 27
M  V30 26 2 27 28
M  V30 27 1 27 29
M  V30 28 1 28 30
M  V30 29 1 28 31
M  V30 30 2 29 32
M  V30 31 2 30 33
M  V30 32 2 34 35
M  V30 33 1 35 36
M  V30 34 1 35 37
M  V30 35 1 36 38
M  V30 36 1 38 39
M  V30 37 1 39 40
M  V30 38 2 40 41
M  V30 39 1 40 42
M  V30 40 1 41 43
M  V30 41 2 42 44
M  V30 42 2 43 45
M  V30 43 1 43 46
M  V30 44 1 45 47
M  V30 45 1 7 8
M  V30 46 1 32 33
M  V30 47 1 44 45
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000811A1-20220106-C00004

>  <Row No>
914

$$$$
US20220000812A1-20220106-C00001
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00021001.cdx

>  <name>
US20220000812A1-20220106-C00001

>  <Row No>
915

$$$$
US20220000812A1-20220106-C00004
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00024001.cdx

>  <name>
US20220000812A1-20220106-C00004

>  <Row No>
916

$$$$
US20220000812A1-20220106-C00005
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00025001.cdx

>  <name>
US20220000812A1-20220106-C00005

>  <Row No>
917

$$$$
US20220000812A1-20220106-C00006
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00026001.cdx

>  <name>
US20220000812A1-20220106-C00006

>  <Row No>
918

$$$$
US20220000812A1-20220106-C00007
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00027001.cdx

>  <name>
US20220000812A1-20220106-C00007

>  <Row No>
919

$$$$
US20220000812A1-20220106-C00008
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00028001.cdx

>  <name>
US20220000812A1-20220106-C00008

>  <Row No>
920

$$$$
US20220000812A1-20220106-C00009
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7641 1.3252 0.0 0
M  V30 3 C -0.0477 2.6505 0.0 0
M  V30 4 C -2.2924 1.3611 0.0 0
M  V30 5 N 1.4088 2.6864 0.0 0
M  V30 6 C -0.8118 3.9758 0.0 0
M  V30 7 C -3.0565 2.6864 0.0 0
M  V30 8 C 2.1252 4.0117 0.0 0
M  V30 9 C -2.3401 4.0117 0.0 0
M  V30 10 N -4.5848 2.7222 0.0 0 CHG=1
M  V30 11 O 1.3611 5.337 0.0 0
M  V30 12 C 3.5818 4.0475 0.0 0
M  V30 13 O -5.3489 4.0475 0.0 0
M  V30 14 O -5.3489 1.4685 0.0 0 CHG=-1
M  V30 15 C 4.3101 5.3728 0.0 0
M  V30 16 C 4.3101 2.7938 0.0 0
M  V30 17 O 3.546 6.6981 0.0 0
M  V30 18 C 5.7668 5.4086 0.0 0
M  V30 19 C 5.7668 2.8296 0.0 0
M  V30 20 Cl 6.4832 6.7339 0.0 0
M  V30 21 C 6.4832 4.1549 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 1 7 9
M  V30 22 1 19 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00030001.cdx

>  <name>
US20220000812A1-20220106-C00009

>  <Row No>
921

$$$$
US20220000812A1-20220106-C00010
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7666 1.3296 0.0 0
M  V30 3 C -0.0479 2.6593 0.0 0
M  V30 4 C -2.2999 1.3656 0.0 0
M  V30 5 N 1.4135 2.6952 0.0 0
M  V30 6 C -0.8145 3.989 0.0 0
M  V30 7 C -3.0666 2.6952 0.0 0
M  V30 8 C 2.1322 4.0249 0.0 0
M  V30 9 N -0.0958 5.3187 0.0 0 CHG=1
M  V30 10 C -2.3478 4.0249 0.0 0
M  V30 11 O 2.0963 5.5582 0.0 0
M  V30 12 C 3.5937 4.0609 0.0 0
M  V30 13 O 1.3656 5.3546 0.0 0
M  V30 14 O -0.8624 6.6483 0.0 0 CHG=-1
M  V30 15 C 4.3124 5.3905 0.0 0
M  V30 16 C 4.3124 2.8031 0.0 0
M  V30 17 O 3.5458 6.7202 0.0 0
M  V30 18 C 5.7739 5.4265 0.0 0
M  V30 19 C 5.7739 2.839 0.0 0
M  V30 20 C 6.4926 4.1687 0.0 0
M  V30 21 Cl 6.4926 1.5812 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 9 13
M  V30 13 1 9 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 1 7 10
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00031001.cdx

>  <name>
US20220000812A1-20220106-C00010

>  <Row No>
922

$$$$
US20220000812A1-20220106-C00011
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7203 1.3325 0.0 0
M  V30 3 C -0.048 2.6651 0.0 0
M  V30 4 C 2.1849 1.3685 0.0 0
M  V30 5 N -1.5846 2.7011 0.0 0 CHG=1
M  V30 6 C 0.6722 3.9977 0.0 0
M  V30 7 C 2.9052 2.7011 0.0 0
M  V30 8 O -2.365 4.0337 0.0 0
M  V30 9 O -2.365 1.4406 0.0 0 CHG=-1
M  V30 10 C 2.1369 4.0337 0.0 0
M  V30 11 N 4.3698 2.7371 0.0 0
M  V30 12 C 5.0901 4.0697 0.0 0
M  V30 13 O 4.3098 5.4022 0.0 0
M  V30 14 C 6.5547 4.1057 0.0 0
M  V30 15 C 7.2871 5.4383 0.0 0
M  V30 16 C 7.2871 2.8452 0.0 0
M  V30 17 O 6.5067 6.7708 0.0 0
M  V30 18 C 8.7517 5.4743 0.0 0
M  V30 19 C 8.7517 2.8812 0.0 0
M  V30 20 C 9.484 4.2137 0.0 0
M  V30 21 Cl 10.9486 4.2498 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 20 21
M  V30 21 1 7 10
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00032001.cdx

>  <name>
US20220000812A1-20220106-C00011

>  <Row No>
923

$$$$
US20220000812A1-20220106-C00012
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7643 1.3256 0.0 0
M  V30 3 C -0.0477 2.6512 0.0 0
M  V30 4 C -2.2929 1.3614 0.0 0
M  V30 5 N 1.4092 2.687 0.0 0
M  V30 6 C -0.824 3.9768 0.0 0
M  V30 7 C -3.0692 2.687 0.0 0
M  V30 8 C 2.1257 4.0126 0.0 0
M  V30 9 C -2.3526 4.0126 0.0 0
M  V30 10 N -4.5978 2.7228 0.0 0 CHG=1
M  V30 11 O 1.3495 5.3383 0.0 0
M  V30 12 C 3.5827 4.0485 0.0 0
M  V30 13 O -5.3741 4.0485 0.0 0
M  V30 14 O -5.3741 1.4689 0.0 0 CHG=-1
M  V30 15 C 4.3112 2.7945 0.0 0
M  V30 16 C 4.3112 5.3741 0.0 0
M  V30 17 Cl 3.5469 1.5405 0.0 0
M  V30 18 C 5.7682 2.8303 0.0 0
M  V30 19 O 3.5469 6.6997 0.0 0
M  V30 20 C 5.7682 5.4099 0.0 0
M  V30 21 C 6.4847 4.156 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 2 16 20
M  V30 20 2 18 21
M  V30 21 1 7 9
M  V30 22 1 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00033001.cdx

>  <name>
US20220000812A1-20220106-C00012

>  <Row No>
924

$$$$
US20220000812A1-20220106-C00013
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7645 1.326 0.0 0
M  V30 3 C -0.0477 2.652 0.0 0
M  V30 4 C -2.2936 1.3618 0.0 0
M  V30 5 N 1.4096 2.6878 0.0 0
M  V30 6 C -0.8123 3.978 0.0 0
M  V30 7 C -3.0582 2.6878 0.0 0
M  V30 8 C 2.1383 4.0139 0.0 0
M  V30 9 C -2.3414 4.0139 0.0 0
M  V30 10 O 1.3618 5.3399 0.0 0
M  V30 11 C 3.5958 4.0497 0.0 0
M  V30 12 N -3.106 5.3399 0.0 0 CHG=1
M  V30 13 C 4.3125 5.3757 0.0 0
M  V30 14 C 4.3125 2.7954 0.0 0
M  V30 15 O -2.3892 6.6659 0.0 0
M  V30 16 O -4.6351 5.3757 0.0 0 CHG=-1
M  V30 17 O 3.536 6.7018 0.0 0
M  V30 18 C 5.77 5.4116 0.0 0
M  V30 19 C 5.77 2.8312 0.0 0
M  V30 20 C 6.4867 4.1572 0.0 0
M  V30 21 Cl 6.4867 1.5769 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 2 14 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 1 7 9
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00034001.cdx

>  <name>
US20220000812A1-20220106-C00013

>  <Row No>
925

$$$$
US20220000812A1-20220106-C00014
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.732 1.3321 0.0 0
M  V30 3 C -0.036 2.6642 0.0 0
M  V30 4 C 2.1961 1.3681 0.0 0
M  V30 5 N -1.5721 2.7002 0.0 0 CHG=1
M  V30 6 C 0.696 3.9963 0.0 0
M  V30 7 C 2.9162 2.7002 0.0 0
M  V30 8 O -2.3521 4.0323 0.0 0
M  V30 9 O -2.3521 1.4401 0.0 0 CHG=-1
M  V30 10 C 2.1601 4.0323 0.0 0
M  V30 11 N 4.3803 2.7362 0.0 0
M  V30 12 C 5.1004 4.0683 0.0 0
M  V30 13 O 4.3203 5.4004 0.0 0
M  V30 14 C 6.5645 4.1043 0.0 0
M  V30 15 C 7.2966 2.8442 0.0 0
M  V30 16 C 7.2966 5.4364 0.0 0
M  V30 17 Cl 6.5165 1.5841 0.0 0
M  V30 18 C 8.7607 2.8802 0.0 0
M  V30 19 O 6.5165 6.7685 0.0 0
M  V30 20 C 8.7607 5.4724 0.0 0
M  V30 21 C 9.4808 4.2123 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 2 16 20
M  V30 20 2 18 21
M  V30 21 1 7 10
M  V30 22 1 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00035001.cdx

>  <name>
US20220000812A1-20220106-C00014

>  <Row No>
926

$$$$
US20220000812A1-20220106-C00015
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.733 1.3338 0.0 0
M  V30 3 C -0.036 2.6677 0.0 0
M  V30 4 C 2.199 1.3699 0.0 0
M  V30 5 N -1.5741 2.7037 0.0 0 CHG=1
M  V30 6 C 0.6969 4.0015 0.0 0
M  V30 7 C 2.92 2.7037 0.0 0
M  V30 8 O -2.3432 4.0376 0.0 0
M  V30 9 O -2.3432 1.442 0.0 0 CHG=-1
M  V30 10 C 2.163 4.0376 0.0 0
M  V30 11 N 4.386 2.7398 0.0 0
M  V30 12 C 5.107 4.0736 0.0 0
M  V30 13 O 4.326 5.4075 0.0 0
M  V30 14 C 6.5731 4.1097 0.0 0
M  V30 15 C 7.3061 5.4435 0.0 0
M  V30 16 C 7.3061 2.8479 0.0 0
M  V30 17 O 6.525 6.7774 0.0 0
M  V30 18 C 8.7721 5.4796 0.0 0
M  V30 19 C 8.7721 2.884 0.0 0
M  V30 20 C 9.4931 4.2178 0.0 0
M  V30 21 Cl 9.4931 1.6222 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 1 7 10
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00036001.cdx

>  <name>
US20220000812A1-20220106-C00015

>  <Row No>
927

$$$$
US20220000812A1-20220106-C00016
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7659 1.3284 0.0 0
M  V30 3 C -0.0478 2.6569 0.0 0
M  V30 4 C -2.2979 1.3644 0.0 0
M  V30 5 N 1.4122 2.6929 0.0 0
M  V30 6 C -0.8258 3.9854 0.0 0
M  V30 7 C -3.0639 2.6929 0.0 0
M  V30 8 C 2.1303 4.0214 0.0 0
M  V30 9 C -2.3577 4.0214 0.0 0
M  V30 10 N -4.5958 2.7288 0.0 0 CHG=1
M  V30 11 O 1.3524 5.3499 0.0 0
M  V30 12 C 3.5905 4.0573 0.0 0
M  V30 13 O -5.3618 4.0573 0.0 0
M  V30 14 O -5.3618 1.4721 0.0 0 CHG=-1
M  V30 15 C 4.3206 2.8006 0.0 0
M  V30 16 C 4.3206 5.3858 0.0 0
M  V30 17 C 5.7807 2.8365 0.0 0
M  V30 18 C 5.7807 5.4217 0.0 0
M  V30 19 Cl 6.4988 1.5798 0.0 0
M  V30 20 C 6.4988 4.165 0.0 0
M  V30 21 O 6.4988 6.7502 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 1 18 21
M  V30 21 1 7 9
M  V30 22 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00037001.cdx

>  <name>
US20220000812A1-20220106-C00016

>  <Row No>
928

$$$$
US20220000812A1-20220106-C00017
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7674 1.331 0.0 0
M  V30 3 C -2.3023 1.367 0.0 0
M  V30 4 C -0.0479 2.6621 0.0 0
M  V30 5 N -3.0698 0.1079 0.0 0 CHG=1
M  V30 6 C -3.0698 2.6981 0.0 0
M  V30 7 N 1.415 2.6981 0.0 0
M  V30 8 C -0.8154 3.9932 0.0 0
M  V30 9 O -4.6047 0.1438 0.0 0
M  V30 10 O -2.3383 -1.1511 0.0 0 CHG=-1
M  V30 11 C -2.3383 4.0291 0.0 0
M  V30 12 C 2.1464 4.0291 0.0 0
M  V30 13 O 1.379 5.3602 0.0 0
M  V30 14 C 3.6094 4.0651 0.0 0
M  V30 15 C 4.3409 5.3962 0.0 0
M  V30 16 C 4.3409 2.806 0.0 0
M  V30 17 O 3.5734 6.7272 0.0 0
M  V30 18 C 5.8039 5.4321 0.0 0
M  V30 19 C 5.8039 2.842 0.0 0
M  V30 20 C 6.5234 4.173 0.0 0
M  V30 21 Cl 6.5234 1.5828 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 7 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 1 8 11
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00038001.cdx

>  <name>
US20220000812A1-20220106-C00017

>  <Row No>
929

$$$$
US20220000812A1-20220106-C00018
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7314 1.331 0.0 0
M  V30 3 C -0.0359 2.6621 0.0 0
M  V30 4 C 2.1944 1.367 0.0 0
M  V30 5 N -1.5708 2.698 0.0 0 CHG=1
M  V30 6 C 0.6955 3.9931 0.0 0
M  V30 7 C 2.9139 2.698 0.0 0
M  V30 8 O -2.3503 4.0291 0.0 0
M  V30 9 O -2.3503 1.4389 0.0 0 CHG=-1
M  V30 10 C 2.1584 4.0291 0.0 0
M  V30 11 N 4.3768 2.734 0.0 0
M  V30 12 C 5.0963 4.0651 0.0 0
M  V30 13 O 4.3169 5.3961 0.0 0
M  V30 14 C 6.5593 4.101 0.0 0
M  V30 15 C 7.2908 5.4321 0.0 0
M  V30 16 C 7.2908 2.8419 0.0 0
M  V30 17 O 6.5233 6.7632 0.0 0
M  V30 18 C 8.7537 5.4681 0.0 0
M  V30 19 C 8.7537 2.8779 0.0 0
M  V30 20 Cl 9.4732 6.7991 0.0 0
M  V30 21 C 9.4732 4.209 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 1 7 10
M  V30 22 1 19 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00039001.cdx

>  <name>
US20220000812A1-20220106-C00018

>  <Row No>
930

$$$$
US20220000812A1-20220106-C00019
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7699 1.3148 0.0 0
M  V30 3 C -0.0473 2.6296 0.0 0
M  V30 4 C -2.2861 1.3503 0.0 0
M  V30 5 O 1.3977 2.6652 0.0 0
M  V30 6 C -0.8173 3.9445 0.0 0
M  V30 7 C -3.0561 2.6652 0.0 0
M  V30 8 C -2.3335 3.98 0.0 0
M  V30 9 C -4.5723 2.7007 0.0 0
M  V30 10 O -5.3422 4.0155 0.0 0
M  V30 11 N -5.3422 1.4569 0.0 0
M  V30 12 C -6.8584 1.4925 0.0 0
M  V30 13 C -7.6284 0.2487 0.0 0
M  V30 14 C -7.6284 2.8073 0.0 0
M  V30 15 Cl -6.9177 -0.995 0.0 0
M  V30 16 C -9.1446 0.2842 0.0 0
M  V30 17 C -9.1446 2.8429 0.0 0
M  V30 18 C -9.9027 1.5991 0.0 0
M  V30 19 N -11.4189 1.6346 0.0 0 CHG=1
M  V30 20 O -12.1889 2.9495 0.0 0
M  V30 21 O -12.1889 0.3908 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 18 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 7 8
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00040001.cdx

>  <name>
US20220000812A1-20220106-C00019

>  <Row No>
931

$$$$
US20220000812A1-20220106-C00020
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.766 1.3285 0.0 0
M  V30 3 C -0.0478 2.6571 0.0 0
M  V30 4 C -2.298 1.3644 0.0 0
M  V30 5 N 1.4123 2.693 0.0 0
M  V30 6 C -0.8138 3.9856 0.0 0
M  V30 7 C -3.064 2.693 0.0 0
M  V30 8 C 2.1304 4.0215 0.0 0
M  V30 9 C -2.3459 4.0215 0.0 0
M  V30 10 N -4.596 2.7289 0.0 0 CHG=1
M  V30 11 O 1.3644 5.3501 0.0 0
M  V30 12 C 3.5906 4.0574 0.0 0
M  V30 13 O -5.374 4.0574 0.0 0
M  V30 14 O -5.374 1.4721 0.0 0 CHG=-1
M  V30 15 C 4.3207 2.8007 0.0 0
M  V30 16 C 4.3207 5.386 0.0 0
M  V30 17 Cl 3.5428 1.5439 0.0 0
M  V30 18 C 5.781 2.8366 0.0 0
M  V30 19 C 5.781 5.4219 0.0 0
M  V30 20 C 6.5111 4.1651 0.0 0
M  V30 21 O 7.9713 4.2011 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 20 21
M  V30 21 1 7 9
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00041001.cdx

>  <name>
US20220000812A1-20220106-C00020

>  <Row No>
932

$$$$
US20220000812A1-20220106-C00021
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.758 1.3148 0.0 0
M  V30 3 C -2.2742 1.3503 0.0 0
M  V30 4 C -0.0473 2.6296 0.0 0
M  V30 5 C -3.0323 2.6651 0.0 0
M  V30 6 C -0.8054 3.9444 0.0 0
M  V30 7 C -2.3098 3.98 0.0 0
M  V30 8 C -4.5485 2.7007 0.0 0
M  V30 9 O -3.0679 5.2948 0.0 0
M  V30 10 O -5.3066 4.0155 0.0 0
M  V30 11 N -5.3066 1.4569 0.0 0
M  V30 12 C -6.8228 1.4925 0.0 0
M  V30 13 C -7.5809 0.2487 0.0 0
M  V30 14 C -7.5809 2.8073 0.0 0
M  V30 15 F -6.8702 -0.995 0.0 0
M  V30 16 C -9.0971 0.2842 0.0 0
M  V30 17 C -9.0971 2.8428 0.0 0
M  V30 18 C -9.8552 1.5991 0.0 0
M  V30 19 N -11.3714 1.6346 0.0 0 CHG=1
M  V30 20 O -12.1295 2.9494 0.0 0
M  V30 21 O -12.1295 0.3908 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 18 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 6 7
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00042001.cdx

>  <name>
US20220000812A1-20220106-C00021

>  <Row No>
933

$$$$
US20220000812A1-20220106-C00022
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7319 -1.2599 0.0 0
M  V30 3 C 2.1958 -1.2239 0.0 0
M  V30 4 C -0.0479 -2.5198 0.0 0
M  V30 5 O 2.9158 0.1079 0.0 0
M  V30 6 C 2.9158 -2.4838 0.0 0
M  V30 7 C -1.5839 -2.4838 0.0 0
M  V30 8 C 0.6719 -3.7798 0.0 0
M  V30 9 C 2.1358 -3.7438 0.0 0
M  V30 10 O -2.3638 -1.1519 0.0 0
M  V30 11 N -2.3638 -3.7438 0.0 0
M  V30 12 C -3.8998 -3.7078 0.0 0
M  V30 13 C -4.6797 -4.9677 0.0 0
M  V30 14 C -4.6797 -2.3758 0.0 0
M  V30 15 Cl -3.9598 -6.2276 0.0 0
M  V30 16 C -6.2156 -4.9317 0.0 0
M  V30 17 C -6.2156 -2.3398 0.0 0
M  V30 18 C -6.9956 -3.5998 0.0 0
M  V30 19 N -8.5315 -3.5638 0.0 0 CHG=1
M  V30 20 O -9.3115 -2.2318 0.0 0
M  V30 21 O -9.3115 -4.8237 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 6 9
M  V30 9 2 7 10
M  V30 10 1 7 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 18 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 8 9
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00043001.cdx

>  <name>
US20220000812A1-20220106-C00022

>  <Row No>
934

$$$$
US20220000812A1-20220106-C00023
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7779 1.3285 0.0 0
M  V30 3 C -2.31 1.3644 0.0 0
M  V30 4 C -0.0478 2.6571 0.0 0
M  V30 5 N -3.088 0.1077 0.0 0 CHG=1
M  V30 6 C -3.088 2.693 0.0 0
M  V30 7 N 1.4123 2.693 0.0 0
M  V30 8 C -0.8258 3.9857 0.0 0
M  V30 9 O -4.62 0.1436 0.0 0
M  V30 10 O -2.3698 -1.149 0.0 0 CHG=-1
M  V30 11 C -2.3698 4.0216 0.0 0
M  V30 12 C 2.1305 4.0216 0.0 0
M  V30 13 O 1.3525 5.3502 0.0 0
M  V30 14 C 3.5907 4.0575 0.0 0
M  V30 15 C 4.3088 5.3861 0.0 0
M  V30 16 C 4.3088 2.8007 0.0 0
M  V30 17 O 3.5309 6.7146 0.0 0
M  V30 18 C 5.7691 5.422 0.0 0
M  V30 19 C 5.7691 2.8366 0.0 0
M  V30 20 C 6.4992 4.1652 0.0 0
M  V30 21 Cl 7.9594 4.2011 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 7 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 20 21
M  V30 21 1 8 11
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00044001.cdx

>  <name>
US20220000812A1-20220106-C00023

>  <Row No>
935

$$$$
US20220000812A1-20220106-C00024
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7653 1.3273 0.0 0
M  V30 3 C -0.0478 2.6546 0.0 0
M  V30 4 C -2.2959 1.3632 0.0 0
M  V30 5 N 1.411 2.6905 0.0 0
M  V30 6 C -0.8131 3.9819 0.0 0
M  V30 7 C -3.0612 2.6905 0.0 0
M  V30 8 C 2.1285 4.0178 0.0 0
M  V30 9 C -2.3437 4.0178 0.0 0
M  V30 10 N -4.5918 2.7264 0.0 0 CHG=1
M  V30 11 O 1.3512 5.3452 0.0 0
M  V30 12 C 3.5873 4.0537 0.0 0
M  V30 13 O -5.3571 4.0537 0.0 0
M  V30 14 O -5.3571 1.4708 0.0 0 CHG=-1
M  V30 15 C 4.3168 5.381 0.0 0
M  V30 16 C 4.3168 2.7981 0.0 0
M  V30 17 O 3.5395 6.7084 0.0 0
M  V30 18 C 5.7756 5.4169 0.0 0
M  V30 19 C 5.7756 2.834 0.0 0
M  V30 20 C 6.4931 4.1613 0.0 0
M  V30 21 F 6.4931 1.5784 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 1 7 9
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00045001.cdx

>  <name>
US20220000812A1-20220106-C00024

>  <Row No>
936

$$$$
US20220000812A1-20220106-C00025
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7654 1.3274 0.0 0
M  V30 3 C -0.0478 2.6549 0.0 0
M  V30 4 C -2.2962 1.3633 0.0 0
M  V30 5 N 1.4112 2.6908 0.0 0
M  V30 6 C -0.8132 3.9824 0.0 0
M  V30 7 C -3.0616 2.6908 0.0 0
M  V30 8 C 2.1287 4.0183 0.0 0
M  V30 9 C -2.344 4.0183 0.0 0
M  V30 10 N -4.5924 2.7267 0.0 0 CHG=1
M  V30 11 O 1.3633 5.3458 0.0 0
M  V30 12 C 3.5878 4.0542 0.0 0
M  V30 13 O -5.3697 4.0542 0.0 0
M  V30 14 O -5.3697 1.471 0.0 0 CHG=-1
M  V30 15 C 4.3054 5.3817 0.0 0
M  V30 16 C 4.3054 2.7985 0.0 0
M  V30 17 C 5.7644 5.4176 0.0 0
M  V30 18 C 5.7644 2.8343 0.0 0
M  V30 19 O 6.4939 6.7451 0.0 0
M  V30 20 C 6.4939 4.1618 0.0 0
M  V30 21 Cl 7.953 4.1977 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 1 20 21
M  V30 21 1 7 9
M  V30 22 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00046001.cdx

>  <name>
US20220000812A1-20220106-C00025

>  <Row No>
937

$$$$
US20220000812A1-20220106-C00026
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7652 1.3273 0.0 0
M  V30 3 C -2.2958 1.3631 0.0 0
M  V30 4 C -0.0478 2.6546 0.0 0
M  V30 5 N -3.0731 0.1076 0.0 0 CHG=1
M  V30 6 C -3.0731 2.6905 0.0 0
M  V30 7 N 1.411 2.6905 0.0 0
M  V30 8 C -0.825 3.9819 0.0 0
M  V30 9 O -4.6037 0.1434 0.0 0
M  V30 10 O -2.3437 -1.1479 0.0 0 CHG=-1
M  V30 11 C -2.3437 4.0178 0.0 0
M  V30 12 C 2.1404 4.0178 0.0 0
M  V30 13 O 1.3631 5.3451 0.0 0
M  V30 14 C 3.5992 4.0536 0.0 0
M  V30 15 C 4.3287 5.381 0.0 0
M  V30 16 C 4.3287 2.7981 0.0 0
M  V30 17 O 3.5514 6.7083 0.0 0
M  V30 18 C 5.7875 5.4168 0.0 0
M  V30 19 C 5.7875 2.8339 0.0 0
M  V30 20 Cl 6.505 6.7442 0.0 0
M  V30 21 C 6.505 4.1613 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 7 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 1 8 11
M  V30 22 1 19 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00047001.cdx

>  <name>
US20220000812A1-20220106-C00026

>  <Row No>
938

$$$$
US20220000812A1-20220106-C00027
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.7653 1.3273 0.0 0
M  V30 3 C -0.0478 2.6546 0.0 0
M  V30 4 C -2.2959 1.3632 0.0 0
M  V30 5 N 1.411 2.6905 0.0 0
M  V30 6 C -0.8131 3.9819 0.0 0
M  V30 7 C -3.0612 2.6905 0.0 0
M  V30 8 C 2.1285 4.0178 0.0 0
M  V30 9 C -2.3437 4.0178 0.0 0
M  V30 10 N -4.5918 2.7264 0.0 0 CHG=1
M  V30 11 O 1.3512 5.3452 0.0 0
M  V30 12 C 3.5873 4.0537 0.0 0
M  V30 13 O -5.3571 4.0537 0.0 0
M  V30 14 O -5.3571 1.4708 0.0 0 CHG=-1
M  V30 15 C 4.3168 5.381 0.0 0
M  V30 16 C 4.3168 2.7981 0.0 0
M  V30 17 O 3.5395 6.7084 0.0 0
M  V30 18 C 5.7756 5.4169 0.0 0
M  V30 19 C 5.7756 2.834 0.0 0
M  V30 20 C 6.4931 4.1613 0.0 0
M  V30 21 Cl 6.4931 1.5784 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 1 7 9
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00048001.cdx

>  <name>
US20220000812A1-20220106-C00027

>  <Row No>
939

$$$$
US20220000812A1-20220106-C00028
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.765 1.3268 0.0 0
M  V30 3 C -0.0478 2.6536 0.0 0
M  V30 4 C -2.295 1.3626 0.0 0
M  V30 5 N 1.4104 2.6894 0.0 0
M  V30 6 C -0.8128 3.9804 0.0 0
M  V30 7 C -3.0719 2.6894 0.0 0
M  V30 8 C 2.1276 4.0162 0.0 0
M  V30 9 C -2.3428 4.0162 0.0 0
M  V30 10 N -4.602 2.7253 0.0 0 CHG=1
M  V30 11 O 1.3626 5.3431 0.0 0
M  V30 12 C 3.5859 4.0521 0.0 0
M  V30 13 O -5.3789 4.0521 0.0 0
M  V30 14 O -5.3789 1.4702 0.0 0 CHG=-1
M  V30 15 C 4.3151 2.797 0.0 0
M  V30 16 C 4.3151 5.3789 0.0 0
M  V30 17 Cl 3.5501 1.5419 0.0 0
M  V30 18 C 5.7734 2.8329 0.0 0
M  V30 19 C 5.7734 5.4148 0.0 0
M  V30 20 C 6.4906 4.1597 0.0 0
M  V30 21 O 6.4906 6.7416 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 1 7 9
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00049001.cdx

>  <name>
US20220000812A1-20220106-C00028

>  <Row No>
940

$$$$
US20220000812A1-20220106-C00029
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7663 1.3291 0.0 0
M  V30 3 C -2.2989 1.365 0.0 0
M  V30 4 C -0.0478 2.6582 0.0 0
M  V30 5 N -3.0772 0.1077 0.0 0 CHG=1
M  V30 6 C -3.0772 2.6941 0.0 0
M  V30 7 N 1.4129 2.6941 0.0 0
M  V30 8 C -0.8262 3.9873 0.0 0
M  V30 9 O -4.6099 0.1436 0.0 0
M  V30 10 O -2.3468 -1.1494 0.0 0 CHG=-1
M  V30 11 C -2.3468 4.0232 0.0 0
M  V30 12 C 2.1433 4.0232 0.0 0
M  V30 13 O 1.365 5.3523 0.0 0
M  V30 14 C 3.6041 4.0591 0.0 0
M  V30 15 C 4.3345 2.8018 0.0 0
M  V30 16 C 4.3345 5.3882 0.0 0
M  V30 17 Cl 3.5682 1.5446 0.0 0
M  V30 18 C 5.7953 2.8378 0.0 0
M  V30 19 O 3.5682 6.7173 0.0 0
M  V30 20 C 5.7953 5.4241 0.0 0
M  V30 21 C 6.5138 4.1669 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 7 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 2 16 20
M  V30 20 2 18 21
M  V30 21 1 8 11
M  V30 22 1 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00050001.cdx

>  <name>
US20220000812A1-20220106-C00029

>  <Row No>
941

$$$$
US20220000812A1-20220106-C00030
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.7664 1.3292 0.0 0
M  V30 3 C -0.0479 2.6585 0.0 0
M  V30 4 C -2.2993 1.3652 0.0 0
M  V30 5 N 1.4131 2.6945 0.0 0
M  V30 6 C -0.8263 3.9878 0.0 0
M  V30 7 C -3.0657 2.6945 0.0 0
M  V30 8 C 2.1316 4.0237 0.0 0
M  V30 9 C -2.3591 4.0237 0.0 0
M  V30 10 N -4.5986 2.7304 0.0 0 CHG=1
M  V30 11 O 1.3532 5.353 0.0 0
M  V30 12 C 3.5926 4.0597 0.0 0
M  V30 13 O -5.377 4.0597 0.0 0
M  V30 14 O -5.377 1.4729 0.0 0 CHG=-1
M  V30 15 C 4.3231 2.8022 0.0 0
M  V30 16 C 4.3231 5.389 0.0 0
M  V30 17 C 5.7842 2.8382 0.0 0
M  V30 18 C 5.7842 5.4249 0.0 0
M  V30 19 Cl 6.5147 1.5807 0.0 0
M  V30 20 C 6.5147 4.1675 0.0 0
M  V30 21 O 7.9757 4.2034 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 1 20 21
M  V30 21 1 7 9
M  V30 22 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00051001.cdx

>  <name>
US20220000812A1-20220106-C00030

>  <Row No>
942

$$$$
US20220000812A1-20220106-C00031
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7666 1.3296 0.0 0
M  V30 3 C -0.0479 2.6592 0.0 0
M  V30 4 C -2.2998 1.3655 0.0 0
M  V30 5 N 1.4134 2.6951 0.0 0
M  V30 6 C -0.8265 3.9888 0.0 0
M  V30 7 C -3.0784 2.6951 0.0 0
M  V30 8 C 2.1321 4.0247 0.0 0
M  V30 9 N -0.1078 5.3184 0.0 0 CHG=1
M  V30 10 C -2.3597 4.0247 0.0 0
M  V30 11 O 1.3535 5.3543 0.0 0
M  V30 12 C 3.5935 4.0606 0.0 0
M  V30 13 O 1.3535 5.3543 0.0 0
M  V30 14 O -0.8864 6.648 0.0 0 CHG=-1
M  V30 15 C 4.3122 2.8029 0.0 0
M  V30 16 C 4.3122 5.3902 0.0 0
M  V30 17 C 5.7735 2.8388 0.0 0
M  V30 18 C 5.7735 5.4262 0.0 0
M  V30 19 Cl 6.4922 1.5811 0.0 0
M  V30 20 C 6.4922 4.1684 0.0 0
M  V30 21 O 6.4922 6.7558 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 9 13
M  V30 13 1 9 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 1 18 21
M  V30 21 1 7 10
M  V30 22 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00052001.cdx

>  <name>
US20220000812A1-20220106-C00031

>  <Row No>
943

$$$$
US20220000812A1-20220106-C00032
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7657 -1.2563 0.0 0
M  V30 3 C -2.2972 -1.2204 0.0 0
M  V30 4 C -0.0478 -2.5126 0.0 0
M  V30 5 O -3.0629 0.1076 0.0 0
M  V30 6 C -3.0629 -2.4767 0.0 0
M  V30 7 C -0.8136 -3.7689 0.0 0
M  V30 8 C -4.5944 -2.4408 0.0 0
M  V30 9 C -2.3451 -3.733 0.0 0
M  V30 10 O -4.6303 -0.9093 0.0 0
M  V30 11 N -5.3602 -3.6971 0.0 0
M  V30 12 C -6.8917 -3.6612 0.0 0
M  V30 13 C -7.6574 -4.9175 0.0 0
M  V30 14 C -7.6574 -2.3331 0.0 0
M  V30 15 Cl -6.9395 -6.1738 0.0 0
M  V30 16 C -9.1889 -4.8816 0.0 0
M  V30 17 N -6.9395 -1.005 0.0 0 CHG=1
M  V30 18 C -9.1889 -2.2972 0.0 0
M  V30 19 C -9.9547 -3.5535 0.0 0
M  V30 20 O -5.4798 -0.9691 0.0 0
M  V30 21 O -7.7173 0.323 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 6 8
M  V30 8 2 6 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 2 14 18
M  V30 18 2 16 19
M  V30 19 2 17 20
M  V30 20 1 17 21
M  V30 21 1 7 9
M  V30 22 1 18 19
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00053001.cdx

>  <name>
US20220000812A1-20220106-C00032

>  <Row No>
944

$$$$
US20220000812A1-20220106-C00033
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.7641 1.3252 0.0 0
M  V30 3 C -0.0477 2.6505 0.0 0
M  V30 4 C -2.2924 1.3611 0.0 0
M  V30 5 N 1.4088 2.6864 0.0 0
M  V30 6 C -0.8118 3.9758 0.0 0
M  V30 7 C -3.0565 2.6864 0.0 0
M  V30 8 C 2.1252 4.0117 0.0 0
M  V30 9 C -2.3401 4.0117 0.0 0
M  V30 10 N -4.5848 2.7222 0.0 0 CHG=1
M  V30 11 O 1.3611 5.337 0.0 0
M  V30 12 C 3.5818 4.0475 0.0 0
M  V30 13 O -5.3489 4.0475 0.0 0
M  V30 14 O -5.3489 1.4685 0.0 0 CHG=-1
M  V30 15 C 4.3101 5.3728 0.0 0
M  V30 16 C 4.3101 2.7938 0.0 0
M  V30 17 O 3.546 6.6981 0.0 0
M  V30 18 C 5.7668 5.4086 0.0 0
M  V30 19 C 5.7668 2.8296 0.0 0
M  V30 20 Cl 6.4832 6.7339 0.0 0
M  V30 21 C 6.4832 4.1549 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 1 7 9
M  V30 22 1 19 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00054001.cdx

>  <name>
US20220000812A1-20220106-C00033

>  <Row No>
945

$$$$
US20220000812A1-20220106-C00034
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 F 0.0 0.0 0.0 0
M  V30 2 C -0.7643 1.3255 0.0 0
M  V30 3 C -0.0477 2.6511 0.0 0
M  V30 4 C -2.2929 1.3614 0.0 0
M  V30 5 N 1.4091 2.687 0.0 0
M  V30 6 C -0.824 3.9767 0.0 0
M  V30 7 C -3.0691 2.687 0.0 0
M  V30 8 C 2.1257 4.0126 0.0 0
M  V30 9 C -2.3526 4.0126 0.0 0
M  V30 10 N -4.5977 2.7228 0.0 0 CHG=1
M  V30 11 O 1.3614 5.3382 0.0 0
M  V30 12 C 3.5827 4.0484 0.0 0
M  V30 13 O -5.374 4.0484 0.0 0
M  V30 14 O -5.374 1.4689 0.0 0 CHG=-1
M  V30 15 C 4.3111 5.374 0.0 0
M  V30 16 C 4.3111 2.7945 0.0 0
M  V30 17 O 3.5349 6.6996 0.0 0
M  V30 18 C 5.7681 5.4098 0.0 0
M  V30 19 C 5.7681 2.8303 0.0 0
M  V30 20 C 6.4966 4.1559 0.0 0
M  V30 21 O 7.9535 4.1917 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 20 21
M  V30 21 1 7 9
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00055001.cdx

>  <name>
US20220000812A1-20220106-C00034

>  <Row No>
946

$$$$
US20220000812A1-20220106-C00035
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7791 1.3304 0.0 0
M  V30 3 C -0.0479 2.6609 0.0 0
M  V30 4 C -2.3133 1.3664 0.0 0
M  V30 5 N 1.4143 2.6969 0.0 0
M  V30 6 C -0.827 3.9914 0.0 0
M  V30 7 C -3.0924 2.6969 0.0 0
M  V30 8 C 2.1335 4.0274 0.0 0
M  V30 9 N -0.0958 5.3219 0.0 0 CHG=1
M  V30 10 C -2.3613 4.0274 0.0 0
M  V30 11 O 2.0976 5.5616 0.0 0
M  V30 12 C 3.5958 4.0633 0.0 0
M  V30 13 O 1.3664 5.3578 0.0 0
M  V30 14 O -0.875 6.6524 0.0 0 CHG=-1
M  V30 15 C 4.327 2.8047 0.0 0
M  V30 16 C 4.327 5.3938 0.0 0
M  V30 17 C 5.7893 2.8407 0.0 0
M  V30 18 C 5.7893 5.4298 0.0 0
M  V30 19 F 6.5085 1.5821 0.0 0
M  V30 20 C 6.5085 4.1712 0.0 0
M  V30 21 O 7.9709 4.2071 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 9 13
M  V30 13 1 9 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 1 20 21
M  V30 21 1 7 10
M  V30 22 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00056001.cdx

>  <name>
US20220000812A1-20220106-C00035

>  <Row No>
947

$$$$
US20220000812A1-20220106-C00036
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7699 1.3148 0.0 0
M  V30 3 C -0.0473 2.6296 0.0 0
M  V30 4 C -2.2861 1.3503 0.0 0
M  V30 5 O 1.3977 2.6652 0.0 0
M  V30 6 C -0.8173 3.9445 0.0 0
M  V30 7 C -3.0561 2.6652 0.0 0
M  V30 8 C -2.3335 3.98 0.0 0
M  V30 9 C -4.5723 2.7007 0.0 0
M  V30 10 O -5.3422 4.0155 0.0 0
M  V30 11 N -5.3422 1.4569 0.0 0
M  V30 12 C -6.8584 1.4925 0.0 0
M  V30 13 C -7.6284 0.2487 0.0 0
M  V30 14 C -7.6284 2.8073 0.0 0
M  V30 15 F -6.9177 -0.995 0.0 0
M  V30 16 C -9.1446 0.2842 0.0 0
M  V30 17 C -9.1446 2.8429 0.0 0
M  V30 18 C -9.9027 1.5991 0.0 0
M  V30 19 N -11.4189 1.6346 0.0 0 CHG=1
M  V30 20 O -12.1889 2.9495 0.0 0
M  V30 21 O -12.1889 0.3908 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 18 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 7 8
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00057001.cdx

>  <name>
US20220000812A1-20220106-C00036

>  <Row No>
948

$$$$
US20220000812A1-20220106-C00037
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.759 1.3164 0.0 0
M  V30 3 C -0.0474 2.6328 0.0 0
M  V30 4 C -2.277 1.352 0.0 0
M  V30 5 O 1.3994 2.6684 0.0 0
M  V30 6 C -0.8064 3.9493 0.0 0
M  V30 7 C -3.0479 2.6684 0.0 0
M  V30 8 C -2.3245 3.9849 0.0 0
M  V30 9 C -4.566 2.704 0.0 0
M  V30 10 O -4.6016 4.2221 0.0 0
M  V30 11 N -5.3369 1.4587 0.0 0
M  V30 12 C -6.8549 1.4943 0.0 0
M  V30 13 C -7.6258 0.249 0.0 0
M  V30 14 C -7.6258 2.8107 0.0 0
M  V30 15 Cl -6.9024 -0.9962 0.0 0
M  V30 16 C -9.1439 0.2846 0.0 0
M  V30 17 N -6.9024 4.1272 0.0 0 CHG=1
M  V30 18 C -9.1439 2.8463 0.0 0
M  V30 19 C -9.9148 1.601 0.0 0
M  V30 20 O -5.4555 4.1628 0.0 0
M  V30 21 O -7.6733 5.4436 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 2 14 18
M  V30 18 2 16 19
M  V30 19 2 17 20
M  V30 20 1 17 21
M  V30 21 1 7 8
M  V30 22 1 18 19
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00058001.cdx

>  <name>
US20220000812A1-20220106-C00037

>  <Row No>
949

$$$$
US20220000812A1-20220106-C00038
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7769 1.3267 0.0 0
M  V30 3 C -0.0478 2.6535 0.0 0
M  V30 4 C -2.3069 1.3626 0.0 0
M  V30 5 N 1.4104 2.6894 0.0 0
M  V30 6 C -0.8247 3.9803 0.0 0
M  V30 7 C -3.0838 2.6894 0.0 0
M  V30 8 C 2.1276 4.0161 0.0 0
M  V30 9 N -0.0956 5.307 0.0 0 CHG=1
M  V30 10 C -2.3547 4.0161 0.0 0
M  V30 11 O 2.0917 5.5461 0.0 0
M  V30 12 C 3.5858 4.052 0.0 0
M  V30 13 O 1.3626 5.3429 0.0 0
M  V30 14 O -0.8725 6.6338 0.0 0 CHG=-1
M  V30 15 C 4.3149 5.3788 0.0 0
M  V30 16 C 4.3149 2.7969 0.0 0
M  V30 17 O 3.538 6.7055 0.0 0
M  V30 18 C 5.7732 5.4146 0.0 0
M  V30 19 C 5.7732 2.8328 0.0 0
M  V30 20 C 6.4904 4.1596 0.0 0
M  V30 21 Cl 7.9486 4.1954 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 6 9
M  V30 9 2 6 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 9 13
M  V30 13 1 9 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 20 21
M  V30 21 1 7 10
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00059001.cdx

>  <name>
US20220000812A1-20220106-C00038

>  <Row No>
950

$$$$
US20220000812A1-20220106-C00039
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7642 -1.2538 0.0 0
M  V30 3 C -2.2926 -1.2179 0.0 0
M  V30 4 C -0.0477 -2.5076 0.0 0
M  V30 5 O -3.0688 0.1074 0.0 0
M  V30 6 C -3.0688 -2.4718 0.0 0
M  V30 7 C -0.8239 -3.7614 0.0 0
M  V30 8 C -4.5973 -2.4359 0.0 0
M  V30 9 C -2.3404 -3.7256 0.0 0
M  V30 10 O -5.3734 -1.1105 0.0 0
M  V30 11 N -5.3734 -3.6897 0.0 0
M  V30 12 C -6.9019 -3.6539 0.0 0
M  V30 13 C -7.6661 -4.9077 0.0 0
M  V30 14 C -7.6661 -2.3285 0.0 0
M  V30 15 F -6.9497 -6.1616 0.0 0
M  V30 16 C -9.1946 -4.8719 0.0 0
M  V30 17 C -9.1946 -2.2926 0.0 0
M  V30 18 C -9.9708 -3.5465 0.0 0
M  V30 19 N -11.4992 -3.5106 0.0 0 CHG=1
M  V30 20 O -12.2635 -2.1852 0.0 0
M  V30 21 O -12.2635 -4.7644 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 6 8
M  V30 8 2 6 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 18 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 7 9
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00060001.cdx

>  <name>
US20220000812A1-20220106-C00039

>  <Row No>
951

$$$$
US20220000812A1-20220106-C00040
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.759 1.3164 0.0 0
M  V30 3 C -0.0474 2.6328 0.0 0
M  V30 4 C -2.277 1.352 0.0 0
M  V30 5 O 1.3994 2.6684 0.0 0
M  V30 6 C -0.8064 3.9493 0.0 0
M  V30 7 C -3.0479 2.6684 0.0 0
M  V30 8 C -2.3245 3.9849 0.0 0
M  V30 9 C -4.566 2.704 0.0 0
M  V30 10 O -4.6016 4.2221 0.0 0
M  V30 11 N -5.3369 1.4587 0.0 0
M  V30 12 C -6.8549 1.4943 0.0 0
M  V30 13 C -7.6258 0.249 0.0 0
M  V30 14 C -7.6258 2.8107 0.0 0
M  V30 15 Cl -6.9024 -0.9962 0.0 0
M  V30 16 C -9.1439 0.2846 0.0 0
M  V30 17 N -6.9024 4.1272 0.0 0 CHG=1
M  V30 18 C -9.1439 2.8463 0.0 0
M  V30 19 C -9.9148 1.601 0.0 0
M  V30 20 O -5.4555 4.1628 0.0 0
M  V30 21 O -7.6733 5.4436 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 1 14 17
M  V30 17 2 14 18
M  V30 18 2 16 19
M  V30 19 2 17 20
M  V30 20 1 17 21
M  V30 21 1 7 8
M  V30 22 1 18 19
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00061001.cdx

>  <name>
US20220000812A1-20220106-C00040

>  <Row No>
952

$$$$
US20220000812A1-20220106-C00041
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.724 1.3175 0.0 0
M  V30 3 C -0.0356 2.635 0.0 0
M  V30 4 C 2.1721 1.3531 0.0 0
M  V30 5 C 0.6884 3.9525 0.0 0
M  V30 6 C -1.5549 2.6706 0.0 0
M  V30 7 C 2.8843 2.6706 0.0 0
M  V30 8 O -0.0712 5.27 0.0 0
M  V30 9 C 2.1365 3.9881 0.0 0
M  V30 10 O -2.3264 3.9881 0.0 0
M  V30 11 N -2.3264 1.4243 0.0 0
M  V30 12 C -3.8457 1.4599 0.0 0
M  V30 13 C -4.6172 0.2136 0.0 0
M  V30 14 C -4.6172 2.7774 0.0 0
M  V30 15 Cl -3.905 -1.0326 0.0 0
M  V30 16 C -6.1365 0.2492 0.0 0
M  V30 17 C -6.1365 2.813 0.0 0
M  V30 18 C -6.908 1.5667 0.0 0
M  V30 19 N -6.908 4.1306 0.0 0 CHG=1
M  V30 20 O -6.184 5.4481 0.0 0
M  V30 21 O -8.4273 4.1662 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 5 9
M  V30 9 2 6 10
M  V30 10 1 6 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 7 9
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00062001.cdx

>  <name>
US20220000812A1-20220106-C00041

>  <Row No>
953

$$$$
US20220000812A1-20220106-C00042
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7323 -1.2606 0.0 0
M  V30 3 C 2.1971 -1.2246 0.0 0
M  V30 4 C -0.036 -2.5213 0.0 0
M  V30 5 O 2.9175 0.108 0.0 0
M  V30 6 C 2.9175 -2.4852 0.0 0
M  V30 7 C -1.5728 -2.4852 0.0 0
M  V30 8 C 0.6963 -3.7819 0.0 0
M  V30 9 C 2.1491 -3.7459 0.0 0
M  V30 10 O -2.3532 -1.1526 0.0 0
M  V30 11 N -2.3532 -3.7459 0.0 0
M  V30 12 C -3.89 -3.7099 0.0 0
M  V30 13 C -4.6584 -4.9705 0.0 0
M  V30 14 C -4.6584 -2.3772 0.0 0
M  V30 15 C -6.1952 -4.9345 0.0 0
M  V30 16 C -6.1952 -2.3412 0.0 0
M  V30 17 Cl -6.9636 -6.1952 0.0 0
M  V30 18 C -6.9636 -3.6018 0.0 0
M  V30 19 N -8.5004 -3.5658 0.0 0 CHG=1
M  V30 20 O -9.2808 -2.2331 0.0 0
M  V30 21 O -9.2808 -4.8265 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 6 9
M  V30 9 2 7 10
M  V30 10 1 7 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 1 15 17
M  V30 17 2 15 18
M  V30 18 1 18 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 8 9
M  V30 22 1 16 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00063001.cdx

>  <name>
US20220000812A1-20220106-C00042

>  <Row No>
954

$$$$
US20220000812A1-20220106-C00043
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7576 1.314 0.0 0
M  V30 3 C -0.0473 2.628 0.0 0
M  V30 4 C -2.2729 1.3495 0.0 0
M  V30 5 C -0.8168 3.9421 0.0 0
M  V30 6 C -3.0305 2.6635 0.0 0
M  V30 7 O -0.1065 5.2561 0.0 0
M  V30 8 C -2.3321 3.9776 0.0 0
M  V30 9 C -4.5458 2.6991 0.0 0
M  V30 10 O -5.3153 4.0131 0.0 0
M  V30 11 N -5.3153 1.456 0.0 0
M  V30 12 C -6.8306 1.4916 0.0 0
M  V30 13 C -7.6001 0.2486 0.0 0
M  V30 14 C -7.6001 2.8056 0.0 0
M  V30 15 F -6.8898 -0.9944 0.0 0
M  V30 16 C -9.1153 0.2841 0.0 0
M  V30 17 C -9.1153 2.8411 0.0 0
M  V30 18 C -9.873 1.5981 0.0 0
M  V30 19 N -11.3883 1.6336 0.0 0 CHG=1
M  V30 20 O -12.1577 2.9477 0.0 0
M  V30 21 O -12.1577 0.3906 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 1 5 7
M  V30 7 2 5 8
M  V30 8 1 6 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 18 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 6 8
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00064001.cdx

>  <name>
US20220000812A1-20220106-C00043

>  <Row No>
955

$$$$
US20220000812A1-20220106-C00044
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.7641 1.3252 0.0 0
M  V30 3 C -0.0477 2.6505 0.0 0
M  V30 4 C -2.2924 1.3611 0.0 0
M  V30 5 N 1.4088 2.6864 0.0 0
M  V30 6 C -0.8118 3.9758 0.0 0
M  V30 7 C -3.0565 2.6864 0.0 0
M  V30 8 C 2.1252 4.0117 0.0 0
M  V30 9 C -2.3401 4.0117 0.0 0
M  V30 10 N -4.5848 2.7222 0.0 0 CHG=1
M  V30 11 O 1.3611 5.337 0.0 0
M  V30 12 C 3.5818 4.0475 0.0 0
M  V30 13 O -5.3489 4.0475 0.0 0
M  V30 14 O -5.3489 1.4685 0.0 0 CHG=-1
M  V30 15 C 4.3101 5.3728 0.0 0
M  V30 16 C 4.3101 2.7938 0.0 0
M  V30 17 Cl 3.546 6.6981 0.0 0
M  V30 18 C 5.7668 5.4086 0.0 0
M  V30 19 C 5.7668 2.8296 0.0 0
M  V30 20 O 6.4832 6.7339 0.0 0
M  V30 21 C 6.4832 4.1549 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 1 7 9
M  V30 22 1 19 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00065001.cdx

>  <name>
US20220000812A1-20220106-C00044

>  <Row No>
956

$$$$
US20220000812A1-20220106-C00045
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.732 -1.2601 0.0 0
M  V30 3 C 2.1962 -1.2241 0.0 0
M  V30 4 C -0.036 -2.5202 0.0 0
M  V30 5 O 2.9163 0.108 0.0 0
M  V30 6 C 2.9163 -2.4842 0.0 0
M  V30 7 C -1.5721 -2.4842 0.0 0
M  V30 8 C 0.696 -3.7804 0.0 0
M  V30 9 C 2.1482 -3.7444 0.0 0
M  V30 10 O -2.3402 -1.1521 0.0 0
M  V30 11 N -2.3402 -3.7444 0.0 0
M  V30 12 C -3.8764 -3.7084 0.0 0
M  V30 13 C -4.6445 -4.9685 0.0 0
M  V30 14 C -4.6445 -2.3762 0.0 0
M  V30 15 Cl -3.9244 -6.2286 0.0 0
M  V30 16 C -6.1806 -4.9325 0.0 0
M  V30 17 C -6.1806 -2.3402 0.0 0
M  V30 18 C -6.9607 -3.6003 0.0 0
M  V30 19 N -6.9607 -1.0081 0.0 0 CHG=1
M  V30 20 O -6.2286 0.324 0.0 0
M  V30 21 O -8.4969 -0.9721 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 6 9
M  V30 9 2 7 10
M  V30 10 1 7 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 8 9
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00066001.cdx

>  <name>
US20220000812A1-20220106-C00045

>  <Row No>
957

$$$$
US20220000812A1-20220106-C00046
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.7643 1.3256 0.0 0
M  V30 3 C -0.0477 2.6512 0.0 0
M  V30 4 C -2.2929 1.3614 0.0 0
M  V30 5 N 1.4092 2.687 0.0 0
M  V30 6 C -0.824 3.9768 0.0 0
M  V30 7 C -3.0692 2.687 0.0 0
M  V30 8 C 2.1257 4.0126 0.0 0
M  V30 9 C -2.3526 4.0126 0.0 0
M  V30 10 N -4.5978 2.7228 0.0 0 CHG=1
M  V30 11 O 1.3495 5.3383 0.0 0
M  V30 12 C 3.5827 4.0485 0.0 0
M  V30 13 O -5.3741 4.0485 0.0 0
M  V30 14 O -5.3741 1.4689 0.0 0 CHG=-1
M  V30 15 C 4.3112 2.7945 0.0 0
M  V30 16 C 4.3112 5.3741 0.0 0
M  V30 17 Cl 3.5469 1.5405 0.0 0
M  V30 18 C 5.7682 2.8303 0.0 0
M  V30 19 O 3.5469 6.6997 0.0 0
M  V30 20 C 5.7682 5.4099 0.0 0
M  V30 21 C 6.4847 4.156 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 1 16 19
M  V30 19 2 16 20
M  V30 20 2 18 21
M  V30 21 1 7 9
M  V30 22 1 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00067001.cdx

>  <name>
US20220000812A1-20220106-C00046

>  <Row No>
958

$$$$
US20220000812A1-20220106-C00047
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7652 1.3273 0.0 0
M  V30 3 C -2.2958 1.3631 0.0 0
M  V30 4 C -0.0478 2.6546 0.0 0
M  V30 5 N -3.0731 0.1076 0.0 0 CHG=1
M  V30 6 C -3.0731 2.6905 0.0 0
M  V30 7 N 1.411 2.6905 0.0 0
M  V30 8 C -0.825 3.9819 0.0 0
M  V30 9 O -4.6037 0.1434 0.0 0
M  V30 10 O -2.3437 -1.1479 0.0 0 CHG=-1
M  V30 11 C -2.3437 4.0178 0.0 0
M  V30 12 C 2.1404 4.0178 0.0 0
M  V30 13 O 1.3631 5.3451 0.0 0
M  V30 14 C 3.5992 4.0536 0.0 0
M  V30 15 C 4.3287 5.381 0.0 0
M  V30 16 C 4.3287 2.7981 0.0 0
M  V30 17 Cl 3.5514 6.7083 0.0 0
M  V30 18 C 5.7875 5.4168 0.0 0
M  V30 19 C 5.7875 2.8339 0.0 0
M  V30 20 O 6.505 6.7442 0.0 0
M  V30 21 C 6.505 4.1613 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 7 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 1 18 20
M  V30 20 2 18 21
M  V30 21 1 8 11
M  V30 22 1 19 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00068001.cdx

>  <name>
US20220000812A1-20220106-C00047

>  <Row No>
959

$$$$
US20220000812A1-20220106-C00048
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.7766 1.3263 0.0 0
M  V30 3 C -0.0597 2.6527 0.0 0
M  V30 4 C -2.3061 1.3621 0.0 0
M  V30 5 N 1.398 2.6885 0.0 0
M  V30 6 C -0.8364 3.979 0.0 0
M  V30 7 C -3.0828 2.6885 0.0 0
M  V30 8 C 2.1149 4.0148 0.0 0
M  V30 9 C -2.3659 4.0148 0.0 0
M  V30 10 N -4.6123 2.7243 0.0 0 CHG=1
M  V30 11 O 2.0791 5.5443 0.0 0
M  V30 12 C 3.5727 4.0507 0.0 0
M  V30 13 O -5.389 4.0507 0.0 0
M  V30 14 O -5.389 1.4697 0.0 0 CHG=-1
M  V30 15 C 4.3016 5.377 0.0 0
M  V30 16 C 4.3016 2.796 0.0 0
M  V30 17 C 5.7594 5.4129 0.0 0
M  V30 18 C 5.7594 2.8319 0.0 0
M  V30 19 O 6.4883 6.7392 0.0 0
M  V30 20 C 6.4883 4.1582 0.0 0
M  V30 21 Cl 7.9461 4.1941 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 1 20 21
M  V30 21 1 7 9
M  V30 22 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00069001.cdx

>  <name>
US20220000812A1-20220106-C00048

>  <Row No>
960

$$$$
US20220000812A1-20220106-C00049
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7251 1.3195 0.0 0
M  V30 3 C -0.0356 2.639 0.0 0
M  V30 4 C 2.1753 1.3551 0.0 0
M  V30 5 C 0.6775 3.9585 0.0 0
M  V30 6 C -1.5572 2.6746 0.0 0
M  V30 7 C 2.8886 2.6746 0.0 0
M  V30 8 O -0.0832 5.278 0.0 0
M  V30 9 C 2.1278 3.9941 0.0 0
M  V30 10 O -2.3299 3.9941 0.0 0
M  V30 11 N -2.3299 1.4264 0.0 0
M  V30 12 C -3.8515 1.4621 0.0 0
M  V30 13 C -4.6242 0.2139 0.0 0
M  V30 14 C -4.6242 2.7816 0.0 0
M  V30 15 F -3.9109 -1.0342 0.0 0
M  V30 16 C -6.1457 0.2496 0.0 0
M  V30 17 C -6.1457 2.8173 0.0 0
M  V30 18 C -6.9065 1.5691 0.0 0
M  V30 19 N -8.4281 1.6048 0.0 0 CHG=1
M  V30 20 O -9.2008 2.9243 0.0 0
M  V30 21 O -9.2008 0.3566 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 5 9
M  V30 9 2 6 10
M  V30 10 1 6 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 18 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 7 9
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00070001.cdx

>  <name>
US20220000812A1-20220106-C00049

>  <Row No>
961

$$$$
US20220000812A1-20220106-C00050
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7319 -1.2599 0.0 0
M  V30 3 C 2.1958 -1.2239 0.0 0
M  V30 4 C -0.0479 -2.5198 0.0 0
M  V30 5 O 2.9158 0.1079 0.0 0
M  V30 6 C 2.9158 -2.4838 0.0 0
M  V30 7 C -1.5839 -2.4838 0.0 0
M  V30 8 C 0.6719 -3.7798 0.0 0
M  V30 9 C 2.1358 -3.7438 0.0 0
M  V30 10 O -2.3638 -1.1519 0.0 0
M  V30 11 N -2.3638 -3.7438 0.0 0
M  V30 12 C -3.8998 -3.7078 0.0 0
M  V30 13 C -4.6797 -4.9677 0.0 0
M  V30 14 C -4.6797 -2.3758 0.0 0
M  V30 15 F -3.9598 -6.2276 0.0 0
M  V30 16 C -6.2156 -4.9317 0.0 0
M  V30 17 C -6.2156 -2.3398 0.0 0
M  V30 18 C -6.9956 -3.5998 0.0 0
M  V30 19 N -8.5315 -3.5638 0.0 0 CHG=1
M  V30 20 O -9.3115 -2.2318 0.0 0
M  V30 21 O -9.3115 -4.8237 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 6 9
M  V30 9 2 7 10
M  V30 10 1 7 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 18 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 8 9
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00071001.cdx

>  <name>
US20220000812A1-20220106-C00050

>  <Row No>
962

$$$$
US20220000812A1-20220106-C00051
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7667 1.3297 0.0 0
M  V30 3 C -2.3001 1.3657 0.0 0
M  V30 4 C -0.0359 2.6595 0.0 0
M  V30 5 N -3.0788 0.1078 0.0 0 CHG=1
M  V30 6 C -3.0788 2.6954 0.0 0
M  V30 7 N 1.4256 2.6954 0.0 0
M  V30 8 C -0.8146 3.9893 0.0 0
M  V30 9 O -4.6122 0.1437 0.0 0
M  V30 10 O -2.36 -1.15 0.0 0 CHG=-1
M  V30 11 C -2.36 4.0252 0.0 0
M  V30 12 C 2.1444 4.0252 0.0 0
M  V30 13 O 1.3657 5.355 0.0 0
M  V30 14 C 3.6059 4.0611 0.0 0
M  V30 15 C 4.3247 5.3909 0.0 0
M  V30 16 C 4.3247 2.8033 0.0 0
M  V30 17 C 5.7862 5.4269 0.0 0
M  V30 18 C 5.7862 2.8392 0.0 0
M  V30 19 O 6.517 6.7566 0.0 0
M  V30 20 C 6.517 4.169 0.0 0
M  V30 21 Cl 7.9786 4.2049 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 7 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 1 20 21
M  V30 21 1 8 11
M  V30 22 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00072001.cdx

>  <name>
US20220000812A1-20220106-C00051

>  <Row No>
963

$$$$
US20220000812A1-20220106-C00052
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7331 1.334 0.0 0
M  V30 3 C -0.036 2.668 0.0 0
M  V30 4 C 2.1993 1.37 0.0 0
M  V30 5 N -1.5744 2.7041 0.0 0 CHG=1
M  V30 6 C 0.697 4.0021 0.0 0
M  V30 7 C 2.9204 2.7041 0.0 0
M  V30 8 O -2.3435 4.0381 0.0 0
M  V30 9 O -2.3435 1.4422 0.0 0 CHG=-1
M  V30 10 C 2.1633 4.0381 0.0 0
M  V30 11 N 4.3867 2.7401 0.0 0
M  V30 12 C 5.1078 4.0742 0.0 0
M  V30 13 O 4.3386 5.4082 0.0 0
M  V30 14 C 6.574 4.1102 0.0 0
M  V30 15 C 7.3071 2.8483 0.0 0
M  V30 16 C 7.3071 5.4443 0.0 0
M  V30 17 Cl 6.526 1.5864 0.0 0
M  V30 18 C 8.7734 2.8844 0.0 0
M  V30 19 C 8.7734 5.4803 0.0 0
M  V30 20 C 9.4945 4.2184 0.0 0
M  V30 21 O 9.4945 6.8144 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 1 7 10
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00073001.cdx

>  <name>
US20220000812A1-20220106-C00052

>  <Row No>
964

$$$$
US20220000812A1-20220106-C00053
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.765 1.3268 0.0 0
M  V30 3 C -0.0478 2.6536 0.0 0
M  V30 4 C -2.295 1.3626 0.0 0
M  V30 5 N 1.4104 2.6894 0.0 0
M  V30 6 C -0.8128 3.9804 0.0 0
M  V30 7 C -3.0719 2.6894 0.0 0
M  V30 8 C 2.1276 4.0162 0.0 0
M  V30 9 C -2.3428 4.0162 0.0 0
M  V30 10 N -4.602 2.7253 0.0 0 CHG=1
M  V30 11 O 1.3626 5.3431 0.0 0
M  V30 12 C 3.5859 4.0521 0.0 0
M  V30 13 O -5.3789 4.0521 0.0 0
M  V30 14 O -5.3789 1.4702 0.0 0 CHG=-1
M  V30 15 C 4.3151 2.797 0.0 0
M  V30 16 C 4.3151 5.3789 0.0 0
M  V30 17 Cl 3.5501 1.5419 0.0 0
M  V30 18 C 5.7734 2.8329 0.0 0
M  V30 19 C 5.7734 5.4148 0.0 0
M  V30 20 C 6.4906 4.1597 0.0 0
M  V30 21 O 6.4906 6.7416 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 1 7 9
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00074001.cdx

>  <name>
US20220000812A1-20220106-C00053

>  <Row No>
965

$$$$
US20220000812A1-20220106-C00054
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.5191 0.0356 0.0 0
M  V30 3 C -2.2905 1.3529 0.0 0
M  V30 4 C -2.2905 -1.2105 0.0 0
M  V30 5 O -1.5666 2.6703 0.0 0
M  V30 6 C -3.8097 1.3885 0.0 0
M  V30 7 C -3.8097 -1.1749 0.0 0
M  V30 8 C -4.5693 0.1424 0.0 0
M  V30 9 C -6.0884 0.178 0.0 0
M  V30 10 O -6.848 1.4954 0.0 0
M  V30 11 N -6.848 -1.0681 0.0 0
M  V30 12 C -8.3671 -1.0325 0.0 0
M  V30 13 C -9.1267 -2.2787 0.0 0
M  V30 14 C -9.1267 0.2848 0.0 0
M  V30 15 F -8.4146 -3.5249 0.0 0
M  V30 16 C -10.6459 -2.2431 0.0 0
M  V30 17 C -10.6459 0.3204 0.0 0
M  V30 18 C -11.4054 -0.9257 0.0 0
M  V30 19 N -12.9246 -0.8901 0.0 0 CHG=1
M  V30 20 O -13.696 0.4272 0.0 0
M  V30 21 O -13.696 -2.1363 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 8 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 18 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 7 8
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00075001.cdx

>  <name>
US20220000812A1-20220106-C00054

>  <Row No>
966

$$$$
US20220000812A1-20220106-C00055
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7642 1.3255 0.0 0
M  V30 3 C -0.0477 2.651 0.0 0
M  V30 4 C -2.2927 1.3613 0.0 0
M  V30 5 N 1.4091 2.6868 0.0 0
M  V30 6 C -0.812 3.9765 0.0 0
M  V30 7 C -3.057 2.6868 0.0 0
M  V30 8 C 2.1375 4.0123 0.0 0
M  V30 9 C -2.3405 4.0123 0.0 0
M  V30 10 O 1.3732 5.3379 0.0 0
M  V30 11 C 3.5944 4.0482 0.0 0
M  V30 12 N -3.1048 5.3379 0.0 0 CHG=1
M  V30 13 C 4.3228 2.7943 0.0 0
M  V30 14 C 4.3228 5.3737 0.0 0
M  V30 15 O -2.3763 6.6634 0.0 0
M  V30 16 O -4.6333 5.3737 0.0 0 CHG=-1
M  V30 17 Cl 3.5466 1.5404 0.0 0
M  V30 18 C 5.7797 2.8301 0.0 0
M  V30 19 C 5.7797 5.4095 0.0 0
M  V30 20 C 6.4962 4.1556 0.0 0
M  V30 21 O 6.4962 6.735 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 2 14 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 1 7 9
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00076001.cdx

>  <name>
US20220000812A1-20220106-C00055

>  <Row No>
967

$$$$
US20220000812A1-20220106-C00056
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7668 1.33 0.0 0
M  V30 3 C -2.3006 1.3659 0.0 0
M  V30 4 C -0.0479 2.66 0.0 0
M  V30 5 N -3.0794 0.1078 0.0 0 CHG=1
M  V30 6 C -3.0794 2.696 0.0 0
M  V30 7 N 1.4139 2.696 0.0 0
M  V30 8 C -0.8148 3.9901 0.0 0
M  V30 9 O -4.6132 0.1437 0.0 0
M  V30 10 O -2.3485 -1.1503 0.0 0 CHG=-1
M  V30 11 C -2.3485 4.026 0.0 0
M  V30 12 C 2.1448 4.026 0.0 0
M  V30 13 O 1.3779 5.3561 0.0 0
M  V30 14 C 3.6067 4.062 0.0 0
M  V30 15 C 4.3376 2.8038 0.0 0
M  V30 16 C 4.3376 5.392 0.0 0
M  V30 17 Cl 3.5707 1.5457 0.0 0
M  V30 18 C 5.7994 2.8398 0.0 0
M  V30 19 C 5.7994 5.428 0.0 0
M  V30 20 C 6.5184 4.1698 0.0 0
M  V30 21 O 6.5184 6.758 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 7 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 1 8 11
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00077001.cdx

>  <name>
US20220000812A1-20220106-C00056

>  <Row No>
968

$$$$
US20220000812A1-20220106-C00057
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7208 1.3335 0.0 0
M  V30 3 C -0.048 2.667 0.0 0
M  V30 4 C 2.1865 1.3695 0.0 0
M  V30 5 N -1.5858 2.703 0.0 0 CHG=1
M  V30 6 C 0.6727 4.0005 0.0 0
M  V30 7 C 2.9073 2.703 0.0 0
M  V30 8 O -2.3667 4.0366 0.0 0
M  V30 9 O -2.3667 1.4416 0.0 0 CHG=-1
M  V30 10 C 2.1384 4.0366 0.0 0
M  V30 11 N 4.373 2.7391 0.0 0
M  V30 12 C 5.0938 4.0726 0.0 0
M  V30 13 O 4.3129 5.4061 0.0 0
M  V30 14 C 6.5595 4.1086 0.0 0
M  V30 15 C 7.2923 5.4422 0.0 0
M  V30 16 C 7.2923 2.8472 0.0 0
M  V30 17 C 8.758 5.4782 0.0 0
M  V30 18 C 8.758 2.8832 0.0 0
M  V30 19 O 9.4908 6.8117 0.0 0
M  V30 20 C 9.4908 4.2168 0.0 0
M  V30 21 Cl 10.9565 4.2528 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 1 20 21
M  V30 21 1 7 10
M  V30 22 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00078001.cdx

>  <name>
US20220000812A1-20220106-C00057

>  <Row No>
969

$$$$
US20220000812A1-20220106-C00058
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7674 1.331 0.0 0
M  V30 3 C -2.3023 1.367 0.0 0
M  V30 4 C -0.0359 2.6621 0.0 0
M  V30 5 N -3.0818 0.1079 0.0 0 CHG=1
M  V30 6 C -3.0818 2.698 0.0 0
M  V30 7 N 1.4269 2.698 0.0 0
M  V30 8 C -0.8034 3.9931 0.0 0
M  V30 9 O -4.6167 0.1438 0.0 0
M  V30 10 O -2.3623 -1.1511 0.0 0 CHG=-1
M  V30 11 C -2.3623 4.0291 0.0 0
M  V30 12 C 2.1464 4.0291 0.0 0
M  V30 13 O 1.367 5.3602 0.0 0
M  V30 14 C 3.6094 4.0651 0.0 0
M  V30 15 C 4.3289 2.806 0.0 0
M  V30 16 C 4.3289 5.3961 0.0 0
M  V30 17 Cl 3.5494 1.5469 0.0 0
M  V30 18 C 5.7919 2.8419 0.0 0
M  V30 19 C 5.7919 5.4321 0.0 0
M  V30 20 C 6.5233 4.173 0.0 0
M  V30 21 O 7.9863 4.209 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 1 4 7
M  V30 7 2 4 8
M  V30 8 2 5 9
M  V30 9 1 5 10
M  V30 10 2 6 11
M  V30 11 1 7 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 20 21
M  V30 21 1 8 11
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00079001.cdx

>  <name>
US20220000812A1-20220106-C00058

>  <Row No>
970

$$$$
US20220000812A1-20220106-C00059
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7141 1.3211 0.0 0
M  V30 3 C -0.0476 2.6422 0.0 0
M  V30 4 C 2.1662 1.3568 0.0 0
M  V30 5 C -1.571 2.6779 0.0 0
M  V30 6 C 0.6665 3.9634 0.0 0
M  V30 7 C 2.8803 2.6779 0.0 0
M  V30 8 O -2.3328 3.9991 0.0 0
M  V30 9 N -2.3328 1.4282 0.0 0
M  V30 10 C 2.1185 3.9991 0.0 0
M  V30 11 C -3.8563 1.4639 0.0 0
M  V30 12 O 2.8327 5.3202 0.0 0
M  V30 13 C -4.618 0.2142 0.0 0
M  V30 14 C -4.618 2.7851 0.0 0
M  V30 15 F -3.9039 -1.0354 0.0 0
M  V30 16 C -6.1415 0.2499 0.0 0
M  V30 17 C -6.1415 2.8208 0.0 0
M  V30 18 C -6.9151 1.571 0.0 0
M  V30 19 N -8.4386 1.6067 0.0 0 CHG=1
M  V30 20 O -9.2123 2.9279 0.0 0
M  V30 21 O -9.2123 0.357 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 9 11
M  V30 11 1 10 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 18 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 7 10
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00080001.cdx

>  <name>
US20220000812A1-20220106-C00059

>  <Row No>
971

$$$$
US20220000812A1-20220106-C00060
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -1.5177 0.0355 0.0 0
M  V30 3 C -2.2765 1.3517 0.0 0
M  V30 4 C -2.2765 -1.2094 0.0 0
M  V30 5 O -1.5532 2.656 0.0 0
M  V30 6 C -3.7942 1.3872 0.0 0
M  V30 7 C -3.7942 -1.1738 0.0 0
M  V30 8 C -4.5531 0.1422 0.0 0
M  V30 9 C -6.0708 0.166 0.0 0
M  V30 10 O -6.8297 1.4821 0.0 0
M  V30 11 N -6.8297 -1.0908 0.0 0
M  V30 12 C -8.3474 -1.0552 0.0 0
M  V30 13 C -9.1181 -2.3002 0.0 0
M  V30 14 C -9.1181 0.2608 0.0 0
M  V30 15 Cl -8.3948 -3.5452 0.0 0
M  V30 16 C -10.6358 -2.2647 0.0 0
M  V30 17 C -10.6358 0.2964 0.0 0
M  V30 18 C -11.3947 -0.9485 0.0 0
M  V30 19 N -11.3947 1.6125 0.0 0 CHG=1
M  V30 20 O -12.9124 1.6362 0.0 0
M  V30 21 O -10.6833 2.9287 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 8 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 7 8
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00081001.cdx

>  <name>
US20220000812A1-20220106-C00060

>  <Row No>
972

$$$$
US20220000812A1-20220106-C00061
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7264 1.3218 0.0 0
M  V30 3 C -0.0357 2.6436 0.0 0
M  V30 4 C 2.1792 1.3575 0.0 0
M  V30 5 C -1.56 2.6794 0.0 0
M  V30 6 C 0.6787 3.9655 0.0 0
M  V30 7 C 2.8937 2.6794 0.0 0
M  V30 8 O -2.3221 4.0012 0.0 0
M  V30 9 N -2.334 1.429 0.0 0
M  V30 10 C 2.1316 4.0012 0.0 0
M  V30 11 O 4.3466 2.7151 0.0 0
M  V30 12 C -3.8583 1.4647 0.0 0
M  V30 13 C -4.6324 0.2143 0.0 0
M  V30 14 C -4.6324 2.7865 0.0 0
M  V30 15 F -3.9179 -1.036 0.0 0
M  V30 16 C -6.1567 0.25 0.0 0
M  V30 17 C -6.1567 2.8223 0.0 0
M  V30 18 C -6.9307 1.5719 0.0 0
M  V30 19 N -8.455 1.6076 0.0 0 CHG=1
M  V30 20 O -9.1457 0.2977 0.0 0
M  V30 21 O -9.3005 2.8818 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 1 9 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 18 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 7 10
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00082001.cdx

>  <name>
US20220000812A1-20220106-C00061

>  <Row No>
973

$$$$
US20220000812A1-20220106-C00062
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.769 1.3133 0.0 0
M  V30 3 C -0.0473 2.6266 0.0 0
M  V30 4 C -2.2835 1.3488 0.0 0
M  V30 5 O 1.3961 2.6621 0.0 0
M  V30 6 C -0.8163 3.94 0.0 0
M  V30 7 C -3.0526 2.6621 0.0 0
M  V30 8 C -2.3308 3.9755 0.0 0
M  V30 9 C -4.567 2.6976 0.0 0
M  V30 10 O -5.3243 4.0109 0.0 0
M  V30 11 N -5.3243 1.4553 0.0 0
M  V30 12 C -6.8388 1.4908 0.0 0
M  V30 13 C -7.6078 0.2484 0.0 0
M  V30 14 C -7.6078 2.8041 0.0 0
M  V30 15 Cl -6.8979 -0.9938 0.0 0
M  V30 16 C -9.1223 0.2839 0.0 0
M  V30 17 C -9.1223 2.8396 0.0 0
M  V30 18 C -9.8914 1.5973 0.0 0
M  V30 19 N -9.8914 4.1529 0.0 0 CHG=1
M  V30 20 O -11.4059 4.2003 0.0 0
M  V30 21 O -9.1696 5.4663 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 6 8
M  V30 8 1 7 9
M  V30 9 2 9 10
M  V30 10 1 9 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 7 8
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00083001.cdx

>  <name>
US20220000812A1-20220106-C00062

>  <Row No>
974

$$$$
US20220000812A1-20220106-C00063
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7749 1.3233 0.0 0
M  V30 3 C -0.0476 2.6467 0.0 0
M  V30 4 C -2.301 1.3591 0.0 0
M  V30 5 N 1.4068 2.6825 0.0 0
M  V30 6 C -0.8226 3.9701 0.0 0
M  V30 7 C -3.0759 2.6825 0.0 0
M  V30 8 C 2.1221 4.0178 0.0 0
M  V30 9 C -2.3487 4.0059 0.0 0
M  V30 10 O 1.3353 5.3293 0.0 0
M  V30 11 C 3.5767 4.0536 0.0 0
M  V30 12 N -3.1355 5.3173 0.0 0 CHG=1
M  V30 13 C 4.3039 5.3769 0.0 0
M  V30 14 C 4.3039 2.8017 0.0 0
M  V30 15 O -4.6616 5.3293 0.0 0
M  V30 16 O -2.4321 6.6526 0.0 0 CHG=-1
M  V30 17 O 3.5171 6.6884 0.0 0
M  V30 18 C 5.7585 5.4127 0.0 0
M  V30 19 C 5.7585 2.8375 0.0 0
M  V30 20 C 6.4857 4.1609 0.0 0
M  V30 21 F 6.4738 1.5737 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 2 14 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 1 7 9
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00084001.cdx

>  <name>
US20220000812A1-20220106-C00063

>  <Row No>
975

$$$$
US20220000812A1-20220106-C00064
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7091 1.3462 0.0 0
M  V30 3 C -0.06 2.6804 0.0 0
M  V30 4 C 2.1756 1.3822 0.0 0
M  V30 5 N -1.5986 2.7165 0.0 0 CHG=1
M  V30 6 C 0.661 4.0146 0.0 0
M  V30 7 C 2.9088 2.7165 0.0 0
M  V30 8 O -2.3799 1.4423 0.0 0
M  V30 9 O -2.3919 4.0387 0.0 0 CHG=-1
M  V30 10 C 2.1275 4.0507 0.0 0
M  V30 11 N 4.3752 2.7525 0.0 0
M  V30 12 C 5.1084 4.0867 0.0 0
M  V30 13 O 4.3392 5.421 0.0 0
M  V30 14 C 6.5749 4.1228 0.0 0
M  V30 15 C 7.3081 2.8607 0.0 0
M  V30 16 C 7.3081 5.457 0.0 0
M  V30 17 Cl 6.5268 1.5866 0.0 0
M  V30 18 C 8.7745 2.8968 0.0 0
M  V30 19 C 8.7745 5.4931 0.0 0
M  V30 20 C 9.4957 4.231 0.0 0
M  V30 21 O 10.9622 4.267 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 2 14 15
M  V30 15 1 14 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 20 21
M  V30 21 1 7 10
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00085001.cdx

>  <name>
US20220000812A1-20220106-C00064

>  <Row No>
976

$$$$
US20220000812A1-20220106-C00065
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7636 -1.2528 0.0 0
M  V30 3 C -2.2908 -1.217 0.0 0
M  V30 4 C -0.0477 -2.5056 0.0 0
M  V30 5 O -3.0545 0.1073 0.0 0
M  V30 6 C -3.0545 -2.4698 0.0 0
M  V30 7 C -0.8232 -3.7585 0.0 0
M  V30 8 C -4.5817 -2.434 0.0 0
M  V30 9 C -2.3266 -3.7227 0.0 0
M  V30 10 O -5.3454 -1.1096 0.0 0
M  V30 11 N -5.3573 -3.6869 0.0 0
M  V30 12 C -6.8846 -3.6511 0.0 0
M  V30 13 C -7.6482 -4.9039 0.0 0
M  V30 14 C -7.6482 -2.3266 0.0 0
M  V30 15 Cl -6.9204 -6.1567 0.0 0
M  V30 16 C -9.1755 -4.8681 0.0 0
M  V30 17 C -9.1755 -2.2908 0.0 0
M  V30 18 C -9.951 -3.5437 0.0 0
M  V30 19 N -9.951 -0.9664 0.0 0 CHG=1
M  V30 20 O -9.2232 0.3579 0.0 0
M  V30 21 O -11.4783 -0.9306 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 6 8
M  V30 8 2 6 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 7 9
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00086001.cdx

>  <name>
US20220000812A1-20220106-C00065

>  <Row No>
977

$$$$
US20220000812A1-20220106-C00066
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.764 1.337 0.0 0
M  V30 3 C -0.0358 2.662 0.0 0
M  V30 4 C -2.292 1.3728 0.0 0
M  V30 5 N 1.4205 2.6979 0.0 0
M  V30 6 C -0.8117 3.9871 0.0 0
M  V30 7 C -3.0679 2.6979 0.0 0
M  V30 8 C 2.1368 4.0349 0.0 0
M  V30 9 C -2.3397 4.0229 0.0 0
M  V30 10 O 1.3608 5.348 0.0 0
M  V30 11 C 3.5932 4.0707 0.0 0
M  V30 12 N -3.1157 5.348 0.0 0 CHG=1
M  V30 13 C 4.3214 2.8172 0.0 0
M  V30 14 C 4.3214 5.3958 0.0 0
M  V30 15 O -4.6437 5.3838 0.0 0
M  V30 16 O -2.3994 6.6731 0.0 0 CHG=-1
M  V30 17 C 5.7778 2.853 0.0 0
M  V30 18 C 5.7778 5.4316 0.0 0
M  V30 19 Cl 6.506 1.5996 0.0 0
M  V30 20 C 6.494 4.1781 0.0 0
M  V30 21 O 6.5179 6.7447 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 2 14 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 1 18 21
M  V30 21 1 7 9
M  V30 22 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00087001.cdx

>  <name>
US20220000812A1-20220106-C00066

>  <Row No>
978

$$$$
US20220000812A1-20220106-C00067
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7142 1.3333 0.0 0
M  V30 3 C -0.0476 2.6547 0.0 0
M  V30 4 C 2.1666 1.369 0.0 0
M  V30 5 C -1.5714 2.6904 0.0 0
M  V30 6 C 0.6666 3.9761 0.0 0
M  V30 7 C 2.8809 2.6904 0.0 0
M  V30 8 O -2.3333 4.0118 0.0 0
M  V30 9 N -2.3452 1.4404 0.0 0
M  V30 10 C 2.119 4.0118 0.0 0
M  V30 11 O 4.3332 2.7261 0.0 0
M  V30 12 C -3.8689 1.4761 0.0 0
M  V30 13 C -4.6427 0.2261 0.0 0
M  V30 14 C -4.6427 2.7975 0.0 0
M  V30 15 Cl -3.9285 -1.0237 0.0 0
M  V30 16 C -6.1665 0.2619 0.0 0
M  V30 17 C -6.1665 2.8332 0.0 0
M  V30 18 C -6.9284 1.5833 0.0 0
M  V30 19 N -6.9284 4.1547 0.0 0 CHG=1
M  V30 20 O -6.2141 5.4761 0.0 0
M  V30 21 O -8.4522 4.1904 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 2 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 1 9 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 7 10
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00088001.cdx

>  <name>
US20220000812A1-20220106-C00067

>  <Row No>
979

$$$$
US20220000812A1-20220106-C00068
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Br 0.0 0.0 0.0 0
M  V30 2 C -0.7564 1.3118 0.0 0
M  V30 3 C -2.2692 1.3473 0.0 0
M  V30 4 C -0.0472 2.6237 0.0 0
M  V30 5 C -3.0256 2.6592 0.0 0
M  V30 6 C -0.8154 3.9356 0.0 0
M  V30 7 C -2.3046 3.9711 0.0 0
M  V30 8 C -4.5384 2.6946 0.0 0
M  V30 9 O -3.0728 5.283 0.0 0
M  V30 10 O -5.2948 4.0065 0.0 0
M  V30 11 N -5.3066 1.4537 0.0 0
M  V30 12 C -6.8194 1.4891 0.0 0
M  V30 13 C -7.5758 0.2481 0.0 0
M  V30 14 C -7.5758 2.801 0.0 0
M  V30 15 Cl -6.8549 -0.9927 0.0 0
M  V30 16 C -9.0886 0.2836 0.0 0
M  V30 17 C -9.0886 2.8365 0.0 0
M  V30 18 C -9.8568 1.5955 0.0 0
M  V30 19 N -9.8568 4.1483 0.0 0 CHG=1
M  V30 20 O -9.1359 5.4602 0.0 0
M  V30 21 O -11.3696 4.1838 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 1 13 16
M  V30 16 2 14 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 19 20
M  V30 20 1 19 21
M  V30 21 1 6 7
M  V30 22 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00089001.cdx

>  <name>
US20220000812A1-20220106-C00068

>  <Row No>
980

$$$$
US20220000812A1-20220106-C00069
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.7643 1.3257 0.0 0
M  V30 3 C -0.0477 2.6514 0.0 0
M  V30 4 C -2.2931 1.3615 0.0 0
M  V30 5 N 1.4093 2.6872 0.0 0
M  V30 6 C -0.8241 3.9771 0.0 0
M  V30 7 C -3.0575 2.6872 0.0 0
M  V30 8 C 2.1378 4.013 0.0 0
M  V30 9 C -2.3528 4.013 0.0 0
M  V30 10 O 1.3735 5.3387 0.0 0
M  V30 11 C 3.5949 4.0488 0.0 0
M  V30 12 N -3.1172 5.3387 0.0 0 CHG=1
M  V30 13 C 4.3115 5.3745 0.0 0
M  V30 14 C 4.3115 2.7947 0.0 0
M  V30 15 O -2.4006 6.6644 0.0 0
M  V30 16 O -4.646 5.3745 0.0 0 CHG=-1
M  V30 17 O 3.5352 6.7002 0.0 0
M  V30 18 C 5.7687 5.4103 0.0 0
M  V30 19 C 5.7687 2.8306 0.0 0
M  V30 20 C 6.4853 4.1563 0.0 0
M  V30 21 Cl 7.9424 4.1921 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 9 12
M  V30 12 2 11 13
M  V30 13 1 11 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 13 17
M  V30 17 1 13 18
M  V30 18 2 14 19
M  V30 19 2 18 20
M  V30 20 1 20 21
M  V30 21 1 7 9
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00090001.cdx

>  <name>
US20220000812A1-20220106-C00069

>  <Row No>
981

$$$$
US20220000812A1-20220106-C00070
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7184 1.329 0.0 0
M  V30 3 C -0.0478 2.6581 0.0 0
M  V30 4 C 2.1792 1.365 0.0 0
M  V30 5 N -1.5805 2.694 0.0 0
M  V30 6 C 0.6705 3.9872 0.0 0
M  V30 7 C 2.8976 2.694 0.0 0
M  V30 8 C -2.3588 1.4368 0.0 0
M  V30 9 C 2.1313 4.0231 0.0 0
M  V30 10 N 4.3584 2.73 0.0 0 CHG=1
M  V30 11 O -1.6403 0.1796 0.0 0
M  V30 12 C -3.8914 1.4727 0.0 0
M  V30 13 O 5.0768 1.4727 0.0 0
M  V30 14 O 5.0768 4.059 0.0 0 CHG=-1
M  V30 15 C -4.6697 0.2155 0.0 0
M  V30 16 C -4.6697 2.8018 0.0 0
M  V30 17 C -6.2023 0.2514 0.0 0
M  V30 18 C -6.2023 2.8377 0.0 0
M  V30 19 Cl -6.9686 -1.0057 0.0 0
M  V30 20 C -6.9686 1.5805 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 1 7 9
M  V30 21 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00093001.cdx

>  <name>
US20220000812A1-20220106-C00070

>  <Row No>
982

$$$$
US20220000812A1-20220106-C00071
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7168 1.3262 0.0 0
M  V30 3 C -0.0477 2.6524 0.0 0
M  V30 4 C 2.1745 1.362 0.0 0
M  V30 5 N -1.5771 2.6883 0.0 0
M  V30 6 C 0.6571 3.9786 0.0 0
M  V30 7 C 2.9033 2.6883 0.0 0
M  V30 8 C -2.3537 1.4337 0.0 0
M  V30 9 C 2.1147 4.0145 0.0 0
M  V30 10 N 4.361 2.7241 0.0 0 CHG=1
M  V30 11 O -1.6368 0.1792 0.0 0
M  V30 12 C -3.8831 1.4696 0.0 0
M  V30 13 O 5.0779 1.4696 0.0 0
M  V30 14 O 5.0779 4.0503 0.0 0 CHG=-1
M  V30 15 C -4.6597 0.215 0.0 0
M  V30 16 C -4.6597 2.7958 0.0 0
M  V30 17 C -6.189 0.2509 0.0 0
M  V30 18 C -6.189 2.8316 0.0 0
M  V30 19 Cl -6.9656 -1.0036 0.0 0
M  V30 20 C -6.9656 1.5771 0.0 0
M  V30 21 O -6.9656 4.1579 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 2 16 18
M  V30 18 1 17 19
M  V30 19 2 17 20
M  V30 20 1 18 21
M  V30 21 1 7 9
M  V30 22 1 18 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00094001.cdx

>  <name>
US20220000812A1-20220106-C00071

>  <Row No>
983

$$$$
US20220000812A1-20220106-C00072
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7169 1.3264 0.0 0
M  V30 3 C -0.0477 2.6528 0.0 0
M  V30 4 C 2.1748 1.3622 0.0 0
M  V30 5 N -1.5773 2.6886 0.0 0
M  V30 6 C 0.6572 3.9792 0.0 0
M  V30 7 C 2.9037 2.6886 0.0 0
M  V30 8 C -2.3421 1.4339 0.0 0
M  V30 9 C 2.115 4.015 0.0 0
M  V30 10 N 4.3616 2.7245 0.0 0 CHG=1
M  V30 11 O -1.6251 0.1792 0.0 0
M  V30 12 C -3.8716 1.4698 0.0 0
M  V30 13 O 5.0785 1.4698 0.0 0
M  V30 14 O 5.0785 4.0509 0.0 0 CHG=-1
M  V30 15 C -4.6484 2.7962 0.0 0
M  V30 16 C -4.6484 0.215 0.0 0
M  V30 17 O -3.9314 4.1226 0.0 0
M  V30 18 C -6.1779 2.832 0.0 0
M  V30 19 C -6.1779 0.2509 0.0 0
M  V30 20 C -4.6962 5.449 0.0 0
M  V30 21 C -6.9546 1.5773 0.0 0
M  V30 22 Cl -6.9546 -1.0037 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 1 17 20
M  V30 20 2 18 21
M  V30 21 1 19 22
M  V30 22 1 7 9
M  V30 23 1 19 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00095001.cdx

>  <name>
US20220000812A1-20220106-C00072

>  <Row No>
984

$$$$
US20220000812A1-20220106-C00073
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 18 19 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7159 1.3245 0.0 0
M  V30 3 C -0.0477 2.6491 0.0 0
M  V30 4 C 2.1718 1.3603 0.0 0
M  V30 5 N -1.5751 2.6849 0.0 0
M  V30 6 C 0.6682 3.9737 0.0 0
M  V30 7 C 2.8878 2.6849 0.0 0
M  V30 8 C -2.3508 1.4319 0.0 0
M  V30 9 C 2.124 4.0095 0.0 0
M  V30 10 O -1.6348 0.1789 0.0 0
M  V30 11 C -3.8782 1.4677 0.0 0
M  V30 12 C -4.6419 2.7923 0.0 0
M  V30 13 C -4.6419 0.2147 0.0 0
M  V30 14 O -3.9259 4.1169 0.0 0
M  V30 15 C -6.1693 2.8281 0.0 0
M  V30 16 C -6.1693 0.2505 0.0 0
M  V30 17 C -6.945 1.5751 0.0 0
M  V30 18 Cl -6.945 -1.0023 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 2 11 12
M  V30 12 1 11 13
M  V30 13 1 12 14
M  V30 14 1 12 15
M  V30 15 2 13 16
M  V30 16 2 15 17
M  V30 17 1 16 18
M  V30 18 1 7 9
M  V30 19 1 16 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00096001.cdx

>  <name>
US20220000812A1-20220106-C00073

>  <Row No>
985

$$$$
US20220000812A1-20220106-C00074
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 0.7169 1.3264 0.0 0
M  V30 3 C -0.0477 2.6528 0.0 0
M  V30 4 C 2.1748 1.3622 0.0 0
M  V30 5 N -1.5773 2.6886 0.0 0
M  V30 6 C 0.6572 3.9792 0.0 0
M  V30 7 C 2.9037 2.6886 0.0 0
M  V30 8 C -2.3421 1.4339 0.0 0
M  V30 9 C -2.3421 4.015 0.0 0
M  V30 10 C 2.115 4.015 0.0 0
M  V30 11 N 4.3616 2.7245 0.0 0 CHG=1
M  V30 12 O -1.6251 0.1792 0.0 0
M  V30 13 C -3.8716 1.4698 0.0 0
M  V30 14 O 5.0785 1.4698 0.0 0
M  V30 15 O 5.0785 4.0509 0.0 0 CHG=-1
M  V30 16 C -4.6484 2.7962 0.0 0
M  V30 17 C -4.6484 0.215 0.0 0
M  V30 18 O -3.9314 4.1226 0.0 0
M  V30 19 C -6.1779 2.832 0.0 0
M  V30 20 C -6.1779 0.2509 0.0 0
M  V30 21 C -6.9546 1.5773 0.0 0
M  V30 22 Cl -6.9546 -1.0037 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 1 5 9
M  V30 9 2 6 10
M  V30 10 1 7 11
M  V30 11 2 8 12
M  V30 12 1 8 13
M  V30 13 2 11 14
M  V30 14 1 11 15
M  V30 15 2 13 16
M  V30 16 1 13 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 2 17 20
M  V30 20 2 19 21
M  V30 21 1 20 22
M  V30 22 1 7 10
M  V30 23 1 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00097001.cdx

>  <name>
US20220000812A1-20220106-C00074

>  <Row No>
986

$$$$
US20220000812A1-20220106-C00075
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 19 20 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C 1.2975 -0.7518 0.0 0
M  V30 3 C 2.595 0.0242 0.0 0
M  V30 4 C 1.2611 -2.2312 0.0 0
M  V30 5 C 3.8925 -0.7154 0.0 0
M  V30 6 C 2.5586 -2.983 0.0 0
M  V30 7 C 3.8561 -2.1948 0.0 0
M  V30 8 C 5.19 0.0606 0.0 0
M  V30 9 O 5.1294 -2.9224 0.0 0
M  V30 10 O 5.1536 1.6128 0.0 0
M  V30 11 N 6.4875 -0.679 0.0 0
M  V30 12 C 7.7851 0.0848 0.0 0
M  V30 13 C 9.0826 -0.6548 0.0 0
M  V30 14 C 9.0705 -2.1584 0.0 0
M  V30 15 C 10.3801 0.1091 0.0 0
M  V30 16 C 10.368 -2.8981 0.0 0
M  V30 17 C 11.6776 -0.6305 0.0 0
M  V30 18 C 11.6655 -2.1221 0.0 0
M  V30 19 ? 12.963 -2.8618 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 1 12 13
M  V30 13 2 13 14
M  V30 14 1 13 15
M  V30 15 1 14 16
M  V30 16 2 15 17
M  V30 17 2 16 18
M  V30 18 1 18 19
M  V30 19 1 6 7
M  V30 20 1 17 18
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00100001.cdx

>  <name>
US20220000812A1-20220106-C00075

>  <Row No>
987

$$$$
US20220000812A1-20220106-C00076
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00101001.cdx

>  <name>
US20220000812A1-20220106-C00076

>  <Row No>
988

$$$$
US20220000812A1-20220106-C00077
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 1 0 0 0 0
M  V30 BEGIN ATOM
M  V30 1 ? 0.0 0.0 0.0 0 MASS=3
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00103001.cdx

>  <name>
US20220000812A1-20220106-C00077

>  <Row No>
989

$$$$
US20220000812A1-20220106-C00080
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0357 1.5234 0.0 0
M  V30 3 C -1.3568 2.2971 0.0 0
M  V30 4 C 1.214 2.2971 0.0 0
M  V30 5 N -2.6542 1.5473 0.0 0
M  V30 6 C -1.3925 3.8206 0.0 0
M  V30 7 C 1.1783 3.8206 0.0 0
M  V30 8 C -3.9872 2.309 0.0 0
M  V30 9 C -0.1428 4.5823 0.0 0
M  V30 10 N 2.4399 4.5823 0.0 0 CHG=1
M  V30 11 O -4.0229 3.8325 0.0 0
M  V30 12 C -5.3203 1.6068 0.0 0
M  V30 13 O 2.428 6.1058 0.0 0
M  V30 14 O 3.6778 3.8444 0.0 0 CHG=-1
M  V30 15 C -6.6414 2.3685 0.0 0
M  V30 16 C -5.356 0.1547 0.0 0
M  V30 17 O -6.701 3.892 0.0 0
M  V30 18 C -7.9626 1.6544 0.0 0
M  V30 19 C -6.6771 -0.5594 0.0 0
M  V30 20 C -7.9983 0.2023 0.0 0
M  V30 21 Cl -6.7129 -2.0114 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 1 10 14
M  V30 14 2 12 15
M  V30 15 1 12 16
M  V30 16 1 15 17
M  V30 17 1 15 18
M  V30 18 2 16 19
M  V30 19 2 18 20
M  V30 20 1 19 21
M  V30 21 1 7 9
M  V30 22 1 19 20
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00107001.cdx

>  <name>
US20220000812A1-20220106-C00080

>  <Row No>
990

$$$$
US20220000812A1-20220106-C00081
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 17 18 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0358 1.5315 0.0 0
M  V30 3 C 1.2204 2.2973 0.0 0
M  V30 4 C -1.364 2.2973 0.0 0
M  V30 5 C 1.1845 3.8289 0.0 0
M  V30 6 C -1.3999 3.8289 0.0 0
M  V30 7 C -0.1435 4.5947 0.0 0
M  V30 8 C 2.4529 4.5947 0.0 0
M  V30 9 O -0.1794 6.1263 0.0 0
M  V30 10 O 2.417 6.1263 0.0 0
M  V30 11 N 3.7093 3.8768 0.0 0
M  V30 12 C 4.9656 4.6426 0.0 0
M  V30 13 C 4.9297 6.1741 0.0 0
M  V30 14 C 6.222 3.9127 0.0 0
M  V30 15 C 6.1861 6.9519 0.0 0
M  V30 16 C 7.4784 4.6785 0.0 0
M  V30 17 C 7.4425 6.222 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 2 15 17
M  V30 17 1 6 7
M  V30 18 1 16 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00108001.cdx

>  <name>
US20220000812A1-20220106-C00081

>  <Row No>
991

$$$$
US20220000812A1-20220106-C00082
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0359 1.5322 0.0 0
M  V30 3 C 1.221 2.3103 0.0 0
M  V30 4 C -1.3646 2.3103 0.0 0
M  V30 5 C 1.1851 3.8426 0.0 0
M  V30 6 C -1.4005 3.8426 0.0 0
M  V30 7 C -0.1436 4.6207 0.0 0
M  V30 8 C 2.442 4.6207 0.0 0
M  V30 9 O -0.1795 6.153 0.0 0
M  V30 10 O 2.4061 6.153 0.0 0
M  V30 11 N 3.699 3.9025 0.0 0
M  V30 12 C 4.9439 4.7045 0.0 0
M  V30 13 C 4.908 6.2368 0.0 0
M  V30 14 C 6.2009 3.9743 0.0 0
M  V30 15 C 6.165 7.0149 0.0 0
M  V30 16 C 7.4578 4.7524 0.0 0
M  V30 17 C 7.4219 6.2847 0.0 0
M  V30 18 N 8.6908 7.0508 0.0 0 CHG=1
M  V30 19 O 8.6789 8.5831 0.0 0
M  V30 20 O 9.9358 6.3086 0.0 0 CHG=-1
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 2 15 17
M  V30 17 1 17 18
M  V30 18 2 18 19
M  V30 19 1 18 20
M  V30 20 1 6 7
M  V30 21 1 16 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00109001.cdx

>  <name>
US20220000812A1-20220106-C00082

>  <Row No>
992

$$$$
US20220000812A1-20220106-C00083
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0359 1.5354 0.0 0
M  V30 3 C 1.2235 2.3031 0.0 0
M  V30 4 C -1.3674 2.3031 0.0 0
M  V30 5 C 1.1875 3.8385 0.0 0
M  V30 6 C -1.4034 3.8385 0.0 0
M  V30 7 C -0.1439 4.6062 0.0 0
M  V30 8 C 2.447 4.6062 0.0 0
M  V30 9 O -0.1799 6.1416 0.0 0
M  V30 10 O 2.411 6.1416 0.0 0
M  V30 11 N 3.7066 3.8865 0.0 0
M  V30 12 C 4.9421 4.7022 0.0 0
M  V30 13 C 4.9061 6.2376 0.0 0
M  V30 14 C 6.2016 3.9824 0.0 0
M  V30 15 C 6.1656 7.0053 0.0 0
M  V30 16 C 7.4611 4.7502 0.0 0
M  V30 17 C 7.4252 6.2856 0.0 0
M  V30 18 C 8.7087 7.0413 0.0 0
M  V30 19 O 8.6727 8.5767 0.0 0
M  V30 20 C 9.9442 6.2976 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 2 15 17
M  V30 17 1 17 18
M  V30 18 2 18 19
M  V30 19 1 18 20
M  V30 20 1 6 7
M  V30 21 1 16 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00110001.cdx

>  <name>
US20220000812A1-20220106-C00083

>  <Row No>
993

$$$$
US20220000812A1-20220106-C00084
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 20 21 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0359 1.5335 0.0 0
M  V30 3 C 1.222 2.3123 0.0 0
M  V30 4 C -1.3658 2.3123 0.0 0
M  V30 5 C 1.1861 3.8459 0.0 0
M  V30 6 C -1.4017 3.8459 0.0 0
M  V30 7 C -0.1437 4.6247 0.0 0
M  V30 8 C 2.4561 4.6007 0.0 0
M  V30 9 O -0.1797 6.1583 0.0 0
M  V30 10 O 2.4201 6.1343 0.0 0
M  V30 11 N 3.7261 3.8818 0.0 0
M  V30 12 C 4.9841 4.6606 0.0 0
M  V30 13 C 4.9482 6.1942 0.0 0
M  V30 14 C 6.2421 3.9417 0.0 0
M  V30 15 C 6.2062 6.973 0.0 0
M  V30 16 C 7.5001 4.7205 0.0 0
M  V30 17 C 7.4642 6.2421 0.0 0
M  V30 18 C 8.7582 6.961 0.0 0
M  V30 19 O 8.7222 8.4946 0.0 0
M  V30 20 N 9.9683 6.1822 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 2 15 17
M  V30 17 1 17 18
M  V30 18 2 18 19
M  V30 19 1 18 20
M  V30 20 1 6 7
M  V30 21 1 16 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00111001.cdx

>  <name>
US20220000812A1-20220106-C00084

>  <Row No>
994

$$$$
US20220000812A1-20220106-C00085
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0357 1.5257 0.0 0
M  V30 3 C -1.3588 2.2886 0.0 0
M  V30 4 C 1.2158 2.2886 0.0 0
M  V30 5 N -2.6224 1.5019 0.0 0
M  V30 6 C -1.3946 3.8144 0.0 0
M  V30 7 C 1.18 3.8144 0.0 0
M  V30 8 C -3.9455 2.2648 0.0 0
M  V30 9 C -0.143 4.5892 0.0 0
M  V30 10 S 2.4316 4.5892 0.0 0
M  V30 11 O -3.9812 3.7905 0.0 0
M  V30 12 C -5.2686 1.5496 0.0 0
M  V30 13 O 2.3959 3.1349 0.0 0
M  V30 14 O 2.3959 6.1149 0.0 0
M  V30 15 C 3.6832 3.862 0.0 0
M  V30 16 C -6.5917 2.3244 0.0 0
M  V30 17 C -5.3044 0.0953 0.0 0
M  V30 18 O -6.6275 3.8501 0.0 0
M  V30 19 C -7.9149 1.6092 0.0 0
M  V30 20 C -6.6275 -0.6317 0.0 0
M  V30 21 C -7.9506 0.1549 0.0 0
M  V30 22 Cl -6.6633 -2.086 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 2 10 13
M  V30 13 2 10 14
M  V30 14 1 10 15
M  V30 15 2 12 16
M  V30 16 1 12 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 2 17 20
M  V30 20 2 19 21
M  V30 21 1 20 22
M  V30 22 1 7 9
M  V30 23 1 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00112001.cdx

>  <name>
US20220000812A1-20220106-C00085

>  <Row No>
995

$$$$
US20220000812A1-20220106-C00086
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 25 27 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0361 1.5437 0.0 0
M  V30 3 C 1.2301 2.3156 0.0 0
M  V30 4 C -1.3749 2.3156 0.0 0
M  V30 5 C 1.194 3.8594 0.0 0
M  V30 6 C -1.411 3.8594 0.0 0
M  V30 7 C -0.1447 4.6312 0.0 0
M  V30 8 C 2.4603 4.6312 0.0 0
M  V30 9 O -0.1809 6.175 0.0 0
M  V30 10 O 2.4241 6.175 0.0 0
M  V30 11 N 3.7267 3.9076 0.0 0
M  V30 12 C 4.9569 4.7519 0.0 0
M  V30 13 C 4.9207 6.2956 0.0 0
M  V30 14 C 6.2233 4.0282 0.0 0
M  V30 15 C 6.1871 7.0675 0.0 0
M  V30 16 C 7.4896 4.8001 0.0 0
M  V30 17 C 7.4534 6.3318 0.0 0
M  V30 18 C 8.7198 7.1037 0.0 0
M  V30 19 O 8.6836 8.6475 0.0 0
M  V30 20 C 10.0103 6.4283 0.0 0
M  V30 21 C 11.2767 7.2122 0.0 0
M  V30 22 C 9.9741 4.9569 0.0 0
M  V30 23 C 12.543 6.4765 0.0 0
M  V30 24 C 11.2405 4.2332 0.0 0
M  V30 25 C 12.5069 5.0051 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 2 15 17
M  V30 17 1 17 18
M  V30 18 2 18 19
M  V30 19 1 18 20
M  V30 20 2 20 21
M  V30 21 1 20 22
M  V30 22 1 21 23
M  V30 23 2 22 24
M  V30 24 2 23 25
M  V30 25 1 6 7
M  V30 26 1 16 17
M  V30 27 1 24 25
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00113001.cdx

>  <name>
US20220000812A1-20220106-C00086

>  <Row No>
996

$$$$
US20220000812A1-20220106-C00087
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 26 28 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.036 1.5377 0.0 0
M  V30 3 C 1.2253 2.3185 0.0 0
M  V30 4 C -1.3695 2.3185 0.0 0
M  V30 5 C 1.1893 3.8563 0.0 0
M  V30 6 C -1.4055 3.8563 0.0 0
M  V30 7 C -0.1441 4.6371 0.0 0
M  V30 8 C 2.4507 4.6371 0.0 0
M  V30 9 O -0.1802 6.1749 0.0 0
M  V30 10 O 2.4147 6.1749 0.0 0
M  V30 11 N 3.7121 3.9163 0.0 0
M  V30 12 C 4.9375 4.7573 0.0 0
M  V30 13 C 4.9014 6.295 0.0 0
M  V30 14 C 6.1989 4.0365 0.0 0
M  V30 15 C 6.1628 7.0639 0.0 0
M  V30 16 C 7.4603 4.8053 0.0 0
M  V30 17 C 7.4243 6.331 0.0 0
M  V30 18 C 8.6857 7.1119 0.0 0
M  V30 19 O 8.6496 8.6496 0.0 0
M  V30 20 N 9.9711 6.4392 0.0 0
M  V30 21 C 11.2325 7.208 0.0 0
M  V30 22 C 12.4939 6.4872 0.0 0
M  V30 23 C 11.1965 8.7457 0.0 0
M  V30 24 C 13.7553 7.2561 0.0 0
M  V30 25 C 12.4579 9.5266 0.0 0
M  V30 26 C 13.7193 8.7938 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 2 15 17
M  V30 17 1 17 18
M  V30 18 2 18 19
M  V30 19 1 18 20
M  V30 20 1 20 21
M  V30 21 2 21 22
M  V30 22 1 21 23
M  V30 23 1 22 24
M  V30 24 2 23 25
M  V30 25 2 24 26
M  V30 26 1 6 7
M  V30 27 1 16 17
M  V30 28 1 25 26
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00114001.cdx

>  <name>
US20220000812A1-20220106-C00087

>  <Row No>
997

$$$$
US20220000812A1-20220106-C00088
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 22 23 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0357 1.5249 0.0 0
M  V30 3 C -1.3581 2.2993 0.0 0
M  V30 4 C 1.2151 2.2993 0.0 0
M  V30 5 N -2.6447 1.5368 0.0 0
M  V30 6 C -1.3938 3.8242 0.0 0
M  V30 7 C 1.1794 3.8242 0.0 0
M  V30 8 C -3.9791 2.2993 0.0 0
M  V30 9 C -0.1429 4.5986 0.0 0
M  V30 10 C 2.4303 4.5986 0.0 0
M  V30 11 O -4.0148 3.8242 0.0 0
M  V30 12 C -5.3014 1.5844 0.0 0
M  V30 13 F 1.6678 5.921 0.0 0
M  V30 14 F 3.6812 5.361 0.0 0
M  V30 15 F 3.157 3.3476 0.0 0
M  V30 16 C -6.6238 2.3469 0.0 0
M  V30 17 C -5.3372 0.131 0.0 0
M  V30 18 O -6.6596 3.8718 0.0 0
M  V30 19 C -7.9462 1.6321 0.0 0
M  V30 20 C -6.6596 -0.5837 0.0 0
M  V30 21 C -7.982 0.1787 0.0 0
M  V30 22 Cl -6.6953 -2.0372 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 1 3 6
M  V30 6 2 4 7
M  V30 7 1 5 8
M  V30 8 2 6 9
M  V30 9 1 7 10
M  V30 10 2 8 11
M  V30 11 1 8 12
M  V30 12 1 10 13
M  V30 13 1 10 14
M  V30 14 1 10 15
M  V30 15 2 12 16
M  V30 16 1 12 17
M  V30 17 1 16 18
M  V30 18 1 16 19
M  V30 19 2 17 20
M  V30 20 2 19 21
M  V30 21 1 20 22
M  V30 22 1 7 9
M  V30 23 1 20 21
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00115001.cdx

>  <name>
US20220000812A1-20220106-C00088

>  <Row No>
998

$$$$
US20220000812A1-20220106-C00089
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.0359 1.5343 0.0 0
M  V30 3 C 1.2227 2.3135 0.0 0
M  V30 4 C -1.3665 2.3135 0.0 0
M  V30 5 C 1.1867 3.8479 0.0 0
M  V30 6 C -1.4025 3.8479 0.0 0
M  V30 7 C -0.1438 4.6151 0.0 0
M  V30 8 C 2.4334 4.6391 0.0 0
M  V30 9 O -0.1798 6.1495 0.0 0
M  V30 10 O 2.3974 6.1734 0.0 0
M  V30 11 N 3.6921 3.9198 0.0 0
M  V30 12 C 4.9028 4.7709 0.0 0
M  V30 13 C 4.8668 6.3053 0.0 0
M  V30 14 C 6.1614 4.0517 0.0 0
M  V30 15 C 6.1255 7.0845 0.0 0
M  V30 16 C 7.4201 4.8189 0.0 0
M  V30 17 C 7.3842 6.3532 0.0 0
M  V30 18 C 8.6428 7.1324 0.0 0
M  V30 19 F 7.8636 8.463 0.0 0
M  V30 20 F 9.9015 7.9116 0.0 0
M  V30 21 F 9.3741 5.8737 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 2 15 17
M  V30 17 1 17 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 6 7
M  V30 22 1 16 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00116001.cdx

>  <name>
US20220000812A1-20220106-C00089

>  <Row No>
999

$$$$
US20220000812A1-20220106-C00090
Actelion Java MolfileCreator 2.0

  0  0  0  0  0  0              0 V3000
M  V30 BEGIN CTAB
M  V30 COUNTS 21 22 0 0 0
M  V30 BEGIN ATOM
M  V30 1 Cl 0.0 0.0 0.0 0
M  V30 2 C -0.036 1.5363 0.0 0
M  V30 3 C 1.2243 2.3045 0.0 0
M  V30 4 C -1.3683 2.3045 0.0 0
M  V30 5 C 1.1883 3.8409 0.0 0
M  V30 6 C -1.4043 3.8409 0.0 0
M  V30 7 C -0.144 4.6211 0.0 0
M  V30 8 C 2.4486 4.6211 0.0 0
M  V30 9 O -0.18 6.1575 0.0 0
M  V30 10 O 2.4126 6.1575 0.0 0
M  V30 11 N 3.7089 3.901 0.0 0
M  V30 12 C 4.9332 4.7412 0.0 0
M  V30 13 C 6.1935 4.021 0.0 0
M  V30 14 C 4.8972 6.2776 0.0 0
M  V30 15 C 7.4539 4.7892 0.0 0
M  V30 16 C 6.1575 7.0578 0.0 0
M  V30 17 C 7.4179 6.3256 0.0 0
M  V30 18 C 8.7142 4.069 0.0 0
M  V30 19 F 9.4464 5.4013 0.0 0
M  V30 20 F 9.9745 3.3488 0.0 0
M  V30 21 F 7.934 2.7967 0.0 0
M  V30 END ATOM
M  V30 BEGIN BOND
M  V30 1 1 1 2
M  V30 2 2 2 3
M  V30 3 1 2 4
M  V30 4 1 3 5
M  V30 5 2 4 6
M  V30 6 2 5 7
M  V30 7 1 5 8
M  V30 8 1 7 9
M  V30 9 2 8 10
M  V30 10 1 8 11
M  V30 11 1 11 12
M  V30 12 2 12 13
M  V30 13 1 12 14
M  V30 14 1 13 15
M  V30 15 2 14 16
M  V30 16 2 15 17
M  V30 17 1 15 18
M  V30 18 1 18 19
M  V30 19 1 18 20
M  V30 20 1 18 21
M  V30 21 1 6 7
M  V30 22 1 16 17
M  V30 END BOND
M  V30 END CTAB
M  END
>  <Molecule Name>
00117001.cdx

>  <name>
US20220000812A1-20220106-C00090

>  <Row No>
1000

$$$$